Itai Benhar - Publications

Affiliations: 
Tel Aviv University, Tel Aviv-Yafo, Tel Aviv District, Israel 

99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Pichinuk E, Chalik M, Benhar I, Ginat-Koton R, Ziv R, Smorodinsky NI, Haran G, Garbar C, Bensussan A, Meeker A, Guillaume T, Rubinstein DB, Wreschner DH. In vivo anti-MUC1 tumor activity and sequences of high-affinity anti-MUC1-SEA antibodies. Cancer Immunology, Immunotherapy : Cii. 69: 1337-1352. PMID 32219500 DOI: 10.1007/S00262-020-02547-2  0.391
2019 Vaisman-Mentesh A, Rosenstein S, Yavzori M, Dror Y, Fudim E, Ungar B, Kopylov U, Picard O, Kigel A, Ben-Horin S, Benhar I, Wine Y. Molecular Landscape of Anti-Drug Antibodies Reveals the Mechanism of the Immune Response Following Treatment With TNFα Antagonists. Frontiers in Immunology. 10: 2921. PMID 31921180 DOI: 10.3389/Fimmu.2019.02921  0.385
2019 Veiga N, Goldsmith M, Diesendruck Y, Ramishetti S, Rosenblum D, Elinav E, Behlke MA, Benhar I, Peer D. Leukocyte-specific siRNA delivery revealing IRF8 as a potential anti-inflammatory target. Journal of Controlled Release. 313: 33-41. PMID 31634546 DOI: 10.1016/J.Jconrel.2019.10.001  0.313
2019 Kon E, Benhar I. Immune checkpoint inhibitor combinations: Current efforts and important aspects for success Drug Resistance Updates. 45: 13-29. PMID 31382144 DOI: 10.1016/J.Drup.2019.07.004  0.329
2019 Birnboim-Perach R, Grinberg Y, Vaks L, Nahary L, Benhar I. Production of Stabilized Antibody Fragments in the E. coli Bacterial Cytoplasm and in Transiently Transfected Mammalian Cells. Methods of Molecular Biology. 1904: 455-480. PMID 30539486 DOI: 10.1007/978-1-4939-8958-4_23  0.403
2019 Litvak-Greenfeld D, Vaks L, Dror S, Nahary L, Benhar I. BIClonals": Production of Bispecific Antibodies in IgG Format in Transiently Transfected Mammalian Cells. Methods of Molecular Biology. 1904: 431-454. PMID 30539485 DOI: 10.1007/978-1-4939-8958-4_22  0.385
2018 Vaks L, Litvak-Greenfeld D, Dror S, Shefet-Carasso L, Matatov G, Nahary L, Shapira S, Hakim R, Alroy I, Benhar I. Design Principles for Bispecific IgGs, Opportunities and Pitfalls of Artificial Disulfide Bonds. Antibodies. 7: 27. PMID 31544879 DOI: 10.3390/Antib7030027  0.352
2018 Kedmi R, Veiga N, Ramishetti S, Goldsmith M, Rosenblum D, Dammes N, Hazan-Halevy I, Nahary L, Leviatan-Ben-Arye S, Harlev M, Behlke M, Benhar I, Lieberman J, Peer D. A modular platform for targeted RNAi therapeutics. Nature Nanotechnology. PMID 29379205 DOI: 10.1038/S41565-017-0043-5  0.406
2018 Krinsky N, Kaduri M, Zinger A, Shainsky-Roitman J, Goldfeder M, Benhar I, Hershkovitz D, Schroeder A. Synthetic Cells Synthesize Therapeutic Proteins inside Tumors. Advanced Healthcare Materials. 7: 1701163. PMID 29283226 DOI: 10.1002/Adhm.201701163  0.318
2018 Bitton A, Nahary L, Benhar I. Antibody Isolation From a Human Synthetic Combinatorial and Other Libraries of Single-Chain Antibodies. Methods of Molecular Biology. 1701: 349-363. PMID 29116515 DOI: 10.1007/978-1-4939-7447-4_19  0.401
2017 Zafir-Lavie I, Miari R, Sherbo S, Krispel S, Tal O, Liran A, Shatil T, Badinter F, Goltsman H, Shapir N, Benhar I, Neil GA, Panet A. Sustained secretion of anti-tumor necrosis factor α monoclonal antibody from ex vivo genetically engineered dermal tissue demonstrates therapeutic activity in mouse model of rheumatoid arthritis. Journal of Gene Medicine. 19. PMID 28658716 DOI: 10.1002/Jgm.2965  0.341
2017 Grinberg Y, Benhar I. Addressing the Immunogenicity of the Cargo and of the Targeting Antibodies with a Focus on Demmunized Bacterial Toxins and on Antibody-Targeted Human Effector Proteins. Biomedicines. 5: 28. PMID 28574434 DOI: 10.3390/Biomedicines5020028  0.43
2017 Diesendruck Y, Benhar I. Novel immune check point inhibiting antibodies in cancer therapy-Opportunities and challenges. Drug Resistance Updates. 30: 39-47. PMID 28363334 DOI: 10.1016/J.Drup.2017.02.001  0.426
2017 Arber N, Shapira S, Karavani VP, Haviv I, Benhar I. A Novel Anti-CD24 Monoclonal Antibody: Unarmed, Conjugated and Bi-specific, for Targeting Human Malignancies: 204 The American Journal of Gastroenterology. 112. DOI: 10.14309/00000434-201710001-00204  0.378
2016 Krinsky N, Kaduri M, Shainsky-Roitman J, Goldfeder M, Ivanir E, Benhar I, Shoham Y, Schroeder A. A Simple and Rapid Method for Preparing a Cell-Free Bacterial Lysate for Protein Synthesis. Plos One. 11: e0165137. PMID 27768741 DOI: 10.1371/Journal.Pone.0165137  0.3
2016 Weiss R, Bitton A, Nahary L, Arango MT, Benhar I, Blank M, Shoenfeld Y, Chapman J. Cross-reactivity between annexin A2 and Beta-2-glycoprotein I in animal models of antiphospholipid syndrome. Immunologic Research. PMID 27449504 DOI: 10.1007/S12026-016-8840-8  0.319
2016 Halperin A, Shadkchan Y, Pisarevsky E, Szpilman AM, Sandovsky H, Osherov N, Benhar I. Novel Water-Soluble Amphotericin B-PEG Conjugates with Low Toxicity and Potent in Vivo Efficacy. Journal of Medicinal Chemistry. 59: 1197-206. PMID 26816333 DOI: 10.1021/Acs.Jmedchem.5B01862  0.35
2016 Shapira S, Kazanov D, Karavani VP, Benhar I, Arber N. Abstract 3805: A novel anti-CD24 monoclonal antibody, humanized and affinity maturated for targeting gastrointestinal cancers Cancer Research. 76: 3805-3805. DOI: 10.1158/1538-7445.Am2016-3805  0.413
2015 Ben-Horin S, Yavzori M, Benhar I, Fudim E, Picard O, Ungar B, Lee S, Kim S, Eliakim R, Chowers Y. Cross-immunogenicity: antibodies to infliximab in Remicade-treated patients with IBD similarly recognise the biosimilar Remsima. Gut. PMID 25897019 DOI: 10.1136/Gutjnl-2015-309290  0.324
2015 Shefet-Carasso L, Benhar I. Antibody-targeted drugs and drug resistance--challenges and solutions. Drug Resistance Updates. 18: 36-46. PMID 25476546 DOI: 10.1016/J.Drup.2014.11.001  0.435
2015 Shapira S, Kazanov D, Kraus S, Benhar I, Arber N. Sa1928 A Humanization and Affinity Maturation of an Anti-CD24 Monoclonal Antibody Targeting Gastrointestinal Cancers Gastroenterology. 148. DOI: 10.1016/S0016-5085(15)31202-6  0.369
2014 Levi O, Shapira A, Tal B, Benhar I, Eliaz N. Isolating EGFR Overexpressing Carcinoma Cells from Human Whole Blood by Bio-Ferrography. Cytometry. Part B, Clinical Cytometry. PMID 25447785 DOI: 10.1002/Cytob.21212  0.335
2014 Mazor R, Eberle JA, Hu X, Vassall AN, Onda M, Beers R, Lee EC, Kreitman RJ, Lee B, Baker D, King C, Hassan R, Benhar I, Pastan I. Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes. Proceedings of the National Academy of Sciences of the United States of America. 111: 8571-6. PMID 24799704 DOI: 10.1073/Pnas.1405153111  0.488
2014 Artzy-Schnirman A, Abu-Shah E, Dishon M, Soifer H, Sivan Y, Reiter Y, Benhar I, Sivan U. On the limited recognition of inorganic surfaces by short peptides compared with antibodies. Journal of Peptide Science : An Official Publication of the European Peptide Society. 20: 446-50. PMID 24733719 DOI: 10.1002/Psc.2636  0.338
2014 Vaks L, Benhar I. Production of Stabilized scFv Antibody Fragments in the E. coli Bacterial Cytoplasm Methods of Molecular Biology. 1060: 171-184. PMID 24037842 DOI: 10.1007/978-1-62703-586-6_10  0.385
2013 Shimoni M, Herschhorn A, Britan-Rosich Y, Kotler M, Benhar I, Hizi A. The Isolation of Novel Phage Display-Derived Human Recombinant Antibodies Against CCR5, the Major Co-Receptor of HIV Viral Immunology. 26: 277-290. PMID 23941674 DOI: 10.1089/Vim.2012.0029  0.369
2013 Barnea I, Ben-Yosef R, Karaush V, Benhar I, Vexler A. Targeting EGFR-positive cancer cells with cetuximab–ZZ-PE38: Results of in vitro and in vivo studies Head and Neck-Journal For the Sciences and Specialties of the Head and Neck. 35: 1171-1177. PMID 22965815 DOI: 10.1002/Hed.23093  0.341
2013 Mazor R, Vassall AN, Eberle JA, Beers R, Hu X, Benhar I, Pastan I. Abstract 4334: Identification and elimination of T-cell epitopes in recombinant immunotoxins used to treat cancer. Cancer Research. 73: 4334-4334. DOI: 10.1158/1538-7445.Am2013-4334  0.467
2012 Mazor R, Vassall AN, Eberle JA, Beers R, Weldon JE, Venzon DJ, Tsang KY, Benhar I, Pastan I. Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A. Proceedings of the National Academy of Sciences of the United States of America. 109: E3597-603. PMID 23213206 DOI: 10.1073/Pnas.1218138109  0.479
2012 Saggy I, Wine Y, Shefet-Carasso L, Nahary L, Georgiou G, Benhar I. Antibody isolation from immunized animals: comparison of phage display and antibody discovery via V gene repertoire mining. Protein Engineering, Design & Selection : Peds. 25: 539-49. PMID 22988130 DOI: 10.1093/Protein/Gzs060  0.386
2012 Litvak-Greenfeld D, Benhar I. Risks and untoward toxicities of antibody-based immunoconjugates. Advanced Drug Delivery Reviews. 64: 1782-1799. PMID 22659123 DOI: 10.1016/J.Addr.2012.05.013  0.428
2012 Luria Y, Raichlin D, Benhar I. Fluorescent IgG fusion proteins made in E. coli Mabs. 4: 373-384. PMID 22531449 DOI: 10.4161/Mabs.19581  0.36
2012 Pichinuk E, Benhar I, Jacobi O, Chalik M, Weiss L, Ziv R, Sympson C, Karwa A, Smorodinsky NI, Rubinstein DB, Wreschner DH. Antibody targeting of cell-bound MUC1 SEA domain kills tumor cells. Cancer Research. 72: 3324-36. PMID 22507854 DOI: 10.1158/0008-5472.Can-12-0067  0.414
2012 Shapira A, Shapira S, Gal-Tanamy M, Zemel R, Tur-Kaspa R, Benhar I. Removal of hepatitis C virus-infected cells by a zymogenized bacterial toxin Plos One. 7. PMID 22359682 DOI: 10.1371/Journal.Pone.0032320  0.324
2012 Inbar NH, Benhar I. Selection of antibodies from synthetic antibody libraries. Archives of Biochemistry and Biophysics. 526: 87-98. PMID 22244834 DOI: 10.1016/J.Abb.2011.12.028  0.382
2012 Becker N, Benhar I. Antibody-Based Immunotoxins for the Treatment of Cancer Antibodies. 1: 39-69. DOI: 10.3390/Antib1010039  0.447
2012 Pichinuk E, Benhar I, Jacobi O, Ziv R, Smorodinsky N, Rubinstein DB, Wreschner DH. Targeting of tumor cells and tumor stem cells by antibodies specific for the cell-bound alpha/beta junction of MUC1. Journal of Clinical Oncology. 30. DOI: 10.1200/Jco.2012.30.15_Suppl.E13018  0.346
2011 Vaks L, Benhar I. In vivo characteristics of targeted drug-carrying filamentous bacteriophage nanomedicines Journal of Nanobiotechnology. 9: 58-58. PMID 22185583 DOI: 10.1186/1477-3155-9-58  0.399
2011 Vaks L, Benhar I. Antibacterial Application of Engineered Bacteriophage Nanomedicines: Antibody-Targeted, Chloramphenicol Prodrug Loaded Bacteriophages for Inhibiting the Growth of Staphylococcus aureus Bacteria Methods of Molecular Biology. 726: 187-206. PMID 21424451 DOI: 10.1007/978-1-61779-052-2_13  0.429
2011 Shapira A, Gal-Tanamy M, Nahary L, Litvak-Greenfeld D, Zemel R, Tur-Kaspa R, Benhar I. Engineered toxins "zymoxins" are activated by the HCV NS3 protease by removal of an inhibitory protein domain Plos One. 6. PMID 21264238 DOI: 10.1371/Journal.Pone.0015916  0.312
2011 Shapira S, Shapira A, Starr A, Kazanov D, Kraus S, Benhar I, Arber N. An immunoconjugate of anti-CD24 and Pseudomonas exotoxin selectively kills human colorectal tumors in mice. Gastroenterology. 140: 935-46. PMID 21147107 DOI: 10.1053/J.Gastro.2010.12.004  0.306
2011 Shapira S, Kraus S, Kazanov D, Benhar I, Arber N. Novel Anti-CD24 Fluorescent Whole-IgG Antibody (Fluobody Derivative): A Valuable Tool for Research and Diagnosis Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)61435-2  0.315
2010 Shapira A, Benhar I. Toxin-based therapeutic approaches Toxins. 2: 2519-2583. PMID 22069564 DOI: 10.3390/Toxins2112519  0.32
2010 Dälken B, Jabulowsky RA, Oberoi P, Benhar I, Wels WS. Maltose-Binding Protein Enhances Secretion of Recombinant Human Granzyme B Accompanied by In Vivo Processing of a Precursor MBP Fusion Protein Plos One. 5. PMID 21203542 DOI: 10.1371/Journal.Pone.0014404  0.343
2010 Bourbeillon J, Orchard S, Benhar I, Borrebaeck C, de Daruvar A, Dübel S, Frank R, Gibson F, Gloriam D, Haslam N, Hiltker T, Humphrey-Smith I, Hust M, Juncker D, Koegl M, et al. Minimum information about a protein affinity reagent (MIAPAR). Nature Biotechnology. 28: 650-3. PMID 20622827 DOI: 10.1038/Nbt0710-650  0.31
2010 Hartmann C, Müller N, Blaukat A, Koch J, Benhar I, Wels WS. Peptide mimotopes recognized by antibodies cetuximab and matuzumab induce a functionally equivalent anti-EGFR immune response. Oncogene. 29: 4517-27. PMID 20514015 DOI: 10.1038/Onc.2010.195  0.377
2010 Orgad S, Dimant H, Dor-On E, Azriel-Rosenfeld R, Benhar I, Solomon B. TAR1, a human anti-p53 single-chain antibody, restores tumor suppressor function to mutant p53 variants. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 146-54. PMID 20139776 DOI: 10.1097/Cji.0B013E3181Be14Dc  0.3
2010 Giterman-Galam T, Gal-Tanamy M, Bachmatov L, Yi M, Lemon S, Benhar I, Zemel R, Tur-Kaspa R. 773 SINGLE-CHAIN ANTIBODIES INHIBIT HCV INFECTIOUS VIRUS REPLICATION BY PROTEIN DELIVERY Journal of Hepatology. 52: S300. DOI: 10.1016/S0168-8278(10)60775-1  0.327
2009 Hakim R, Benhar I. "Inclonals": IgGs and IgG-enzyme fusion proteins produced in an E. coli expression-refolding system Mabs. 1: 281-287. PMID 20065645 DOI: 10.4161/Mabs.1.3.8492  0.409
2009 Trahtenherts A, Benhar I. An internalizing antibody specific for the human asialoglycoprotein receptor. Hybridoma. 28: 225-233. PMID 19663694 DOI: 10.1089/Hyb.2009.0019  0.335
2009 Nahary L, Trahtenherts A, Benhar I. Isolation of scFvs that inhibit the NS3 protease of hepatitis C virus by a combination of phage display and a bacterial genetic screen. Methods of Molecular Biology. 562: 115-132. PMID 19554291 DOI: 10.1007/978-1-60327-302-2_9  0.347
2009 Nahary L, Benhar I. Design of a Human Synthetic Combinatorial Library of Single-Chain Antibodies Methods of Molecular Biology. 525: 61-80. PMID 19252839 DOI: 10.1007/978-1-59745-554-1_3  0.405
2009 Rubinstein DB, Karmely M, Pichinuk E, Ziv R, Benhar I, Feng N, Smorodinsky NI, Wreschner DH. The MUC1 oncoprotein as a functional target: Immunotoxin binding to α/βjunction mediates cell killing International Journal of Cancer. 124: 46-54. PMID 18821582 DOI: 10.1002/Ijc.23910  0.345
2008 Karmely M, Rubinstein DB, Pichinuk E, Ziv R, Benhar I, Feng N, Wreschner DH. Inhibiting MUC1 a/b chain interaction mediates cytotoxicity of cells expressing MUC1: The MUC1 dyad oncoprotein as a functional target. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 14000. PMID 27948199 DOI: 10.1200/Jco.2008.26.15_Suppl.14000  0.39
2008 Artzy-Schnirman A, Brod E, Epel M, Dines M, Hammer T, Benhar I, Reiter Y, Sivan U. A two-state electronic antigen and an antibody selected to discriminate between these states. Nano Letters. 8: 3398-403. PMID 18788790 DOI: 10.1021/Nl8020895  0.323
2008 Nahary L, Tamarkin A, Kayam N, Sela S, Fry L, Baker B, Powles A, Rogers S, Benhar I. An investigation of antistreptococcal antibody responses in guttate psoriasis. Archives of Dermatological Research. 300: 441-9. PMID 18648827 DOI: 10.1007/S00403-008-0866-X  0.347
2008 Yacoby I, Benhar I. Antibacterial nanomedicine. Nanomedicine (London, England). 3: 329-41. PMID 18510428 DOI: 10.2217/17435889.3.3.329  0.633
2008 Bar H, Yacoby I, Benhar I. Killing cancer cells by targeted drug-carrying phage nanomedicines. Bmc Biotechnology. 8: 37-37. PMID 18387177 DOI: 10.1186/1472-6750-8-37  0.691
2008 Yacoby I, Benhar I. Targeted filamentous bacteriophages as therapeutic agents Expert Opinion On Drug Delivery. 5: 321-329. PMID 18318653 DOI: 10.1517/17425247.5.3.321  0.704
2008 Trahtenherts A, Gal-Tanamy M, Zemel R, Bachmatov L, Loewenstein S, Tur-Kaspa R, Benhar I. Inhibition of hepatitis C virus RNA replicons by peptide aptamers. Antiviral Research. 77: 195-205. PMID 18243349 DOI: 10.1016/J.Antiviral.2007.12.013  0.319
2007 Yacoby I, Benhar I. Targeted anti bacterial therapy. Infectious Disorders Drug Targets. 7: 221-229. PMID 17897058 DOI: 10.2174/187152607782109998  0.708
2007 Mazor Y, Noy R, Wels WS, Benhar I. chFRP5-ZZ-PE38, a large IgG-toxin immunoconjugate outperforms the corresponding smaller FRP5(Fv)-ETA immunotoxin in eradicating ErbB2-expressing tumor xenografts. Cancer Letters. 257: 124-135. PMID 17698286 DOI: 10.1016/J.Canlet.2007.07.009  0.427
2007 Benhar I. Design of synthetic antibody libraries. Expert Opinion On Biological Therapy. 7: 763-779. PMID 17477812 DOI: 10.1517/14712598.7.5.763  0.384
2007 Yacoby I, Bar H, Benhar I. Targeted drug-carrying bacteriophages as antibacterial nanomedicines. Antimicrobial Agents and Chemotherapy. 51: 2156-2163. PMID 17404004 DOI: 10.1128/Aac.00163-07  0.701
2007 Mazor Y, Barnea I, Keydar I, Benhar I. Antibody internalization studied using a novel IgG binding toxin fusion Journal of Immunological Methods. 321: 41-59. PMID 17336321 DOI: 10.1016/J.Jim.2007.01.008  0.458
2007 Machlenkin A, Azriel-Rosenfeld R, Volovitz I, Vadai E, Lev A, Paz A, Goldberger O, Reiter Y, Tzehoval E, Benhar I, Eisenbach L. Preventive and therapeutic vaccination with PAP-3, a novel human prostate cancer peptide, inhibits carcinoma development in HLA transgenic mice. Cancer Immunology, Immunotherapy : Cii. 56: 217-26. PMID 16738849 DOI: 10.1007/S00262-006-0184-0  0.313
2006 Rubinstein DB, Karmely M, Ziv R, Benhar I, Leitner O, Baron S, Katz BZ, Wreschner DH. MUC1/X protein immunization enhances cDNA immunization in generating anti-MUC1 alpha/beta junction antibodies that target malignant cells. Cancer Research. 66: 11247-53. PMID 17145869 DOI: 10.1158/0008-5472.Can-06-1486  0.39
2006 Schnirman AA, Zahavi E, Yeger H, Rosenfeld R, Benhar I, Reiter Y, Sivan U. Antibody Molecules Discriminate between Crystalline Facets of a Gallium Arsenide Semiconductor Nano Letters. 6: 1870-1874. PMID 16967993 DOI: 10.1021/Nl0607636  0.356
2006 Yacoby I, Shamis M, Bar H, Shabat D, Benhar I. Targeting antibacterial agents by using drug-carrying filamentous bacteriophages. Antimicrobial Agents and Chemotherapy. 50: 2087-97. PMID 16723570 DOI: 10.1128/Aac.00169-06  0.703
2005 Shaki-Loewenstein S, Zfania R, Hyland S, Wels WS, Benhar I. A universal strategy for stable intracellular antibodies Journal of Immunological Methods. 303: 19-39. PMID 16045924 DOI: 10.1016/J.Jim.2005.05.004  0.403
2005 Ofir K, Berdichevsky Y, Benhar I, Azriel-Rosenfeld R, Lamed R, Barak Y, Bayer EA, Morag E. Versatile protein microarray based on carbohydrate-binding modules. Proteomics. 5: 1806-14. PMID 15825150 DOI: 10.1002/Pmic.200401078  0.332
2005 Gal-Tanamy M, Zemel R, Berdichevsky Y, Bachmatov L, Tur-Kaspa R, Benhar I. HCV NS3 serine protease-neutralizing single-chain antibodies isolated by a novel genetic screen. Journal of Molecular Biology. 347: 991-1003. PMID 15784258 DOI: 10.1016/J.Jmb.2005.02.020  0.382
2005 Mazor Y, Keydar I, Benhar I. Humanization and epitope mapping of the H23 anti-MUC1 monoclonal antibody reveals a dual epitope specificity. Molecular Immunology. 42: 55-69. PMID 15488944 DOI: 10.1016/J.Molimm.2004.07.013  0.377
2004 Zemel R, Berdichevsky Y, Bachmatov L, Benhar I, Tur-Kaspa R. Inhibition of hepatitis C virus NS3-mediated cell transformation by recombinant intracellular antibodies. Journal of Hepatology. 40: 1000-7. PMID 15158342 DOI: 10.1016/J.Jhep.2004.02.026  0.36
2004 Haus-Cohen M, Assaraf YG, Binyamin L, Benhar I, Reiter Y. Disruption of P-glycoprotein anticancer drug efflux activity by a small recombinant single-chain Fv antibody fragment targeted to an extracellular epitope. International Journal of Cancer. 109: 750-758. PMID 14999785 DOI: 10.1002/Ijc.20037  0.451
2004 Azriel-Rosenfeld R, Valensi M, Benhar I. A human synthetic combinatorial library of arrayable single-chain antibodies based on shuffling in vivo formed CDRs into general framework regions. Journal of Molecular Biology. 335: 177-92. PMID 14659749 DOI: 10.1016/J.Jmb.2003.10.053  0.411
2004 Gal-Tanamy M, Ben-Zeev E, Zemel R, Bachmatov L, Berdichevsky Y, Eisestein M, Benhar I, Tur-Kaspa R. 396 Hepatitis C virus NS3 serine protease-neutralizing single-chain antibodies; isolation and characterization Journal of Hepatology. 40: 118. DOI: 10.1016/S0168-8278(04)90396-0  0.319
2003 Denkberg G, Lev A, Eisenbach L, Benhar I, Reiter Y. Selective targeting of melanoma and APCs using a recombinant antibody with TCR-like specificity directed toward a melanoma differentiation antigen. Journal of Immunology (Baltimore, Md. : 1950). 171: 2197-207. PMID 12928363 DOI: 10.4049/Jimmunol.171.5.2197  0.379
2003 Berdichevsky Y, Zemel R, Bachmatov L, Abramovich A, Koren R, Sathiyamoorthy P, Golan-Goldhirsh A, Tur-Kaspa R, Benhar I. A novel high throughput screening assay for HCV NS3 serine protease inhibitors. Journal of Virological Methods. 107: 245-55. PMID 12505640 DOI: 10.1016/S0166-0934(02)00255-0  0.305
2003 Benhar I, Berdichevsky Y. Large scale production of recombinant antibodies by utilizing cellulose-binding domains. Methods in Molecular Biology (Clifton, N.J.). 207: 443-54. PMID 12412491 DOI: 10.1385/1-59259-334-8:443  0.321
2003 Gal-Tanamy M, Zemel R, Bachmatov L, Berdichevsky Y, Benhar I, Tur-Kaspa R. 299 A novel genetic screen for isolation of neutralizing HCV serine protease single-chain antibodies Hepatology. 38: 300-300. DOI: 10.1016/S0270-9139(03)80342-7  0.318
2002 Benhar I, Reiter Y. Phage display of single-chain antibody constructs. Current Protocols in Immunology. 48. PMID 18432867 DOI: 10.1002/0471142735.Im1019Bs48  0.408
2002 Mazor Y, Gilead S, Benhar I, Gazit E. Identification and characterization of a novel molecular-recognition and self-assembly domain within the islet amyloid polypeptide. Journal of Molecular Biology. 322: 1013-24. PMID 12367525 DOI: 10.1016/S0022-2836(02)00887-2  0.461
2001 Benhar I, Eshkenazi I, Neufeld T, Opatowsky J, Shaky S, Rishpon J. Recombinant single chain antibodies in bioelectrochemical sensors. Talanta. 55: 899-907. PMID 18968440 DOI: 10.1016/S0039-9140(01)00497-0  0.395
2001 Benhar I. Biotechnological applications of phage and cell display Biotechnology Advances. 19: 1-33. PMID 14538090 DOI: 10.1016/S0734-9750(00)00054-9  0.395
2001 Bach H, Mazor Y, Shaky S, Shoham-Lev A, Berdichevsky Y, Gutnick DL, Benhar I. Escherichia coli maltose-binding protein as a molecular chaperone for recombinant intracellular cytoplasmic single-chain antibodies Journal of Molecular Biology. 312: 79-93. PMID 11545587 DOI: 10.1006/Jmbi.2001.4914  0.377
2000 Benhar I, Azriel R, Nahary L, Shaky S, Berdichevsky Y, Tamarkin A, Wels W. Highly efficient selection of phage antibodies mediated by display of antigen as Lpp-OmpA' fusions on live bacteria Journal of Molecular Biology. 301: 893-904. PMID 10966794 DOI: 10.1006/Jmbi.2000.4021  0.413
2000 Frenkel D, Solomon B, Benhar I. Modulation of Alzheimer’s β-amyloid neurotoxicity by site-directed single-chain antibody Journal of Neuroimmunology. 106: 23-31. PMID 10814779 DOI: 10.1016/S0165-5728(99)00232-5  0.367
1999 Berdichevsky Y, Ben-Zeev E, Lamed R, Benhar I. Phage display of a cellulose binding domain from Clostridium thermocellum and its application as a tool for antibody engineering Journal of Immunological Methods. 228: 151-162. PMID 10556552 DOI: 10.1016/S0022-1759(99)00096-4  0.409
1999 Berdichevsky Y, Lamed R, Frenkel D, Gophna U, Bayer EA, Yaron S, Shoham Y, Benhar I. Matrix-assisted refolding of single-chain Fv - Cellulose binding domain fusion proteins Protein Expression and Purification. 17: 249-259. PMID 10545273 DOI: 10.1006/Prep.1999.1125  0.35
1998 Almog O, Benhar I, Vasmatzis G, Tordova M, Lee B, Pastan I, Gilliland GL. Crystal structure of the disulfide-stabilized Fv fragment of anticancer antibody B1: conformational influence of an engineered disulfide bond. Proteins. 31: 128-38. PMID 9593187 DOI: 10.1002/(Sici)1097-0134(19980501)31:2<128::Aid-Prot3>3.0.Co;2-I  0.462
1996 Li M, Dyda F, Benhar I, Pastan I, Davies DR. Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation. Proceedings of the National Academy of Sciences of the United States of America. 93: 6902-6. PMID 8692916 DOI: 10.1073/Pnas.93.14.6902  0.397
1995 Benhar I, Padlan EA, Jung SH, Lee B, Pastan I. Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38. Proceedings of the National Academy of Sciences of the United States of America. 91: 12051-5. PMID 7991583 DOI: 10.1073/Pnas.91.25.12051  0.469
1995 Benhar I, Pastan I. Cloning, expression and characterization of the Fv fragments of the anti-carbohydrate mAbs B1 and B5 as single-chain immunotoxins. Protein Engineering. 7: 1509-15. PMID 7716163 DOI: 10.1093/Protein/7.12.1509  0.458
1995 Benhar I, Reiter Y, Pai LH, Pastan I. Administration of disulfide-stabilized Fv-immunotoxins B1(dsFv)-PE38 and B3(dsFv)-PE38 by continuous infusion increases their efficacy in curing large tumor xenografts in nude mice. International Journal of Cancer. 62: 351-5. PMID 7628878 DOI: 10.1002/Ijc.2910620320  0.424
1995 Li M, Dyda F, Benhar I, Pastan I, Davies DR. The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin. Proceedings of the National Academy of Sciences of the United States of America. 92: 9308-12. PMID 7568123 DOI: 10.1073/Pnas.92.20.9308  0.397
1995 Benhar I, Pastan I. Identification of residues that stabilize the single-chain Fv of monoclonal antibodies B3. The Journal of Biological Chemistry. 270: 23373-80. PMID 7559495 DOI: 10.1074/Jbc.270.40.23373  0.486
1994 Benhar I, Brinkmann U, Webber KO, Pastan I. Mutations of two lysine residues in the CDR loops of a recombinant immunotoxin that reduce its sensitivity to chemical derivatization. Bioconjugate Chemistry. 5: 321-326. PMID 7948099 DOI: 10.1021/Bc00028A007  0.486
1994 Roscoe DM, Jung SH, Benhar I, Pai L, Lee BK, Pastan I. Primate antibody response to immunotoxin: serological and computer-aided analysis of epitopes on a truncated form of Pseudomonas exotoxin. Infection and Immunity. 62: 5055-65. PMID 7927788 DOI: 10.1128/Iai.62.11.5055-5065.1994  0.472
Show low-probability matches.