| Year |
Citation |
Score |
| 2022 |
Kim G, Nakayama L, Blum JA, Akiyama T, Boeynaems S, Chakraborty M, Couthouis J, Tassoni-Tsuchida E, Rodriguez CM, Bassik MC, Gitler AD. Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2. Cell Reports. 41: 111508. PMID 36288714 DOI: 10.1016/j.celrep.2022.111508 |
0.686 |
|
| 2022 |
Guo W, Wang H, Kumar Tharkeshwar A, Couthouis J, Braems E, Masrori P, Van Schoor E, Fan Y, Ahuja K, Moisse M, Jacquemyn M, Furtado Madeiro da Costa R, Gajjar M, Balusu S, Tricot T, et al. CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35993441 DOI: 10.1002/alz.12760 |
0.405 |
|
| 2022 |
Napolioni V, Fredericks CA, Kim Y, Channappa D, Khan RR, Kim LH, Zafar F, Couthouis J, Davidzon GA, Mormino EC, Gitler AD, Montine TJ, Schüle B, Greicius MD. Phenotypic Heterogeneity among p.R202X Carriers in Lewy Body Spectrum Disorders. Biomedicines. 10. PMID 35052839 DOI: 10.3390/biomedicines10010160 |
0.541 |
|
| 2022 |
Eger SJ, Le Guen Y, Khan RR, Hall JN, Kennedy G, Zaharchuk G, Couthouis J, Brooks WS, Velakoulis D, Napolioni V, Belloy ME, Dalgard CL, Mormino EC, Gitler AD, Greicius MD. Confirming Pathogenicity of the F386L Variant in a South Asian Family With Early-Onset Alzheimer Disease. Neurology. Genetics. 8: e647. PMID 34901437 DOI: 10.1212/NXG.0000000000000647 |
0.517 |
|
| 2021 |
Maor-Nof M, Shipony Z, Lopez-Gonzalez R, Nakayama L, Zhang YJ, Couthouis J, Blum JA, Castruita PA, Linares GR, Ruan K, Ramaswami G, Simon DJ, Nof A, Santana M, Han K, et al. p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR). Cell. PMID 33482083 DOI: 10.1016/j.cell.2020.12.025 |
0.756 |
|
| 2020 |
Course MM, Gudsnuk K, Smukowski SN, Winston K, Desai N, Ross JP, Sulovari A, Bourassa CV, Spiegelman D, Couthouis J, Yu CE, Tsuang DW, Jayadev S, Kay MA, Gitler AD, et al. Evolution of a Human-Specific Tandem Repeat Associated with ALS. American Journal of Human Genetics. PMID 32750315 DOI: 10.1016/J.Ajhg.2020.07.004 |
0.614 |
|
| 2020 |
Guttenplan KA, Weigel MK, Adler DI, Couthouis J, Liddelow SA, Gitler AD, Barres BA. Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model. Nature Communications. 11: 3753. PMID 32719333 DOI: 10.1038/S41467-020-17514-9 |
0.767 |
|
| 2020 |
Johnson AG, Flynn RA, Lapointe CP, Ooi YS, Zhao ML, Richards CM, Qiao W, Yamada SB, Couthouis J, Gitler AD, Carette JE, Puglisi JD. A memory of eS25 loss drives resistance phenotypes. Nucleic Acids Research. PMID 32463448 DOI: 10.1093/Nar/Gkaa444 |
0.747 |
|
| 2019 |
Chai N, Haney MS, Couthouis J, Morgens DW, Benjamin A, Wu K, Ousey J, Fang S, Finer S, Bassik MC, Gitler AD. Genome-wide synthetic lethal CRISPR screen identifies FIS1 as a genetic interactor of ALS-linked C9ORF72. Brain Research. 146601. PMID 31843624 DOI: 10.1016/J.Brainres.2019.146601 |
0.736 |
|
| 2019 |
Ullah I, Kakar N, Schrauwen I, Hussain S, Chakchouk I, Liaqat K, Acharya A, Wasif N, Santos-Cortez RLP, Khan S, Aziz A, Lee K, Couthouis J, Horn D, Kragesteen BK, et al. Variants in KIAA0825 underlie autosomal recessive postaxial polydactyly. Human Genetics. PMID 30982135 DOI: 10.1007/S00439-019-02000-0 |
0.607 |
|
| 2019 |
Bieri G, Brahic M, Bousset L, Couthouis J, Kramer NJ, Ma R, Nakayama L, Monbureau M, Defensor E, Schüle B, Shamloo M, Melki R, Gitler AD. LRRK2 modifies α-syn pathology and spread in mouse models and human neurons. Acta Neuropathologica. PMID 30927072 DOI: 10.1007/S00401-019-01995-0 |
0.585 |
|
| 2018 |
Couthouis J, Gitler AD. These violent repeats have violent extends. Neurology. Genetics. 4: e247. PMID 30109264 DOI: 10.1212/Nxg.0000000000000247 |
0.628 |
|
| 2018 |
Kramer NJ, Haney MS, Morgens DW, Jovičić A, Couthouis J, Li A, Ousey J, Ma R, Bieri G, Tsui CK, Shi Y, Hertz NT, Tessier-Lavigne M, Ichida JK, Bassik MC, et al. CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. Nature Genetics. PMID 29507424 DOI: 10.1038/S41588-018-0070-7 |
0.782 |
|
| 2018 |
Tsai PI, Lin CH, Hsieh CH, Papakyrikos AM, Kim MJ, Napolioni V, Schoor C, Couthouis J, Wu RM, Wszolek ZK, Winter D, Greicius MD, Ross OA, Wang X. PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions. Molecular Cell. PMID 29456190 DOI: 10.1016/J.Molcel.2018.01.026 |
0.331 |
|
| 2018 |
Kim Y, Khan RR, Kim LH, Couthouis J, Gitler AD, Channappa D, Plowey ED, Napolioni V, Greicius MD. P1-135: Rare Missense Variants On Znf679 And Ctd-3214H19.16 Segregate In A Family With A History Of Synucleinopathy Alzheimers & Dementia. 14: 324. DOI: 10.1016/J.Jalz.2018.06.138 |
0.527 |
|
| 2017 |
Joly P, Vignaud H, Di Martino J, Ruiz M, Garin R, Restier L, Belmalih A, Marchal C, Cullin C, Arveiler B, Fergelot P, Gitler AD, Lachaux A, Couthouis J, Bouchecareilh M. ERAD defects and the HFE-H63D variant are associated with increased risk of liver damages in Alpha 1-Antitrypsin Deficiency. Plos One. 12: e0179369. PMID 28617828 DOI: 10.1371/Journal.Pone.0179369 |
0.567 |
|
| 2017 |
Khan RR, Napolioni V, Altmann A, Seeley WW, Montine TJ, Coppola G, Chen JA, Plowey ED, Channappa D, Gitler AD, Couthouis J, Flanagan ME, Greicius MD. IDENTIFICATION OF AN ITGA7 VARIANT ASSOCIATED WITH ALZHEIMER’S DISEASE AND MULTIPLE OTHER NEURODEGENERATIVE DISEASES Alzheimer's & Dementia. 13: P193-P194. DOI: 10.1016/J.Jalz.2017.07.050 |
0.583 |
|
| 2017 |
Khan RR, Altmann A, Kim LH, Couthouis J, Napolioni V, Gitler AD, Greicius MD. Novel Missense Variant On Epha1 In A Protected Apoe4 Family Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.745 |
0.542 |
|
| 2016 |
Kramer NJ, Carlomagno Y, Zhang YJ, Almeida S, Cook CN, Gendron TF, Prudencio M, Van Blitterswijk M, Belzil V, Couthouis J, Paul JW, Goodman LD, Daughrity L, Chew J, Garrett A, et al. Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts. Science (New York, N.Y.). 353: 708-12. PMID 27516603 DOI: 10.1126/Science.Aaf7791 |
0.621 |
|
| 2015 |
Cirulli ET, Lasseigne BN, Petrovski S, Sapp PC, Dion PA, Leblond CS, Couthouis J, Lu YF, Wang Q, Krueger BJ, Ren Z, Keebler J, Han Y, Levy SE, Boone BE, et al. Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways. Science (New York, N.Y.). 347: 1436-41. PMID 25700176 DOI: 10.1126/Science.Aaa3650 |
0.669 |
|
| 2014 |
Couthouis J, Raphael AR, Daneshjou R, Gitler AD. Targeted exon capture and sequencing in sporadic amyotrophic lateral sclerosis. Plos Genetics. 10: e1004704. PMID 25299611 DOI: 10.1371/Journal.Pgen.1004704 |
0.686 |
|
| 2014 |
Raphael AR, Couthouis J, Sakamuri S, Siskind C, Vogel H, Day JW, Gitler AD. Congenital muscular dystrophy and generalized epilepsy caused by GMPPB mutations. Brain Research. 1575: 66-71. PMID 24780531 DOI: 10.1016/J.Brainres.2014.04.028 |
0.577 |
|
| 2014 |
Couthouis J, Raphael AR, Siskind C, Findlay AR, Buenrostro JD, Greenleaf WJ, Vogel H, Day JW, Flanigan KM, Gitler AD. Exome sequencing identifies a DNAJB6 mutation in a family with dominantly-inherited limb-girdle muscular dystrophy. Neuromuscular Disorders : Nmd. 24: 431-5. PMID 24594375 DOI: 10.1016/J.Nmd.2014.01.014 |
0.592 |
|
| 2013 |
Chesi A, Staahl BT, JoviÄić A, Couthouis J, Fasolino M, Raphael AR, Yamazaki T, Elias L, Polak M, Kelly C, Williams KL, Fifita JA, Maragakis NJ, Nicholson GA, King OD, et al. Exome sequencing to identify de novo mutations in sporadic ALS trios. Nature Neuroscience. 16: 851-5. PMID 23708140 DOI: 10.1038/Nn.3412 |
0.691 |
|
| 2012 |
Couthouis J, Hart MP, Erion R, King OD, Diaz Z, Nakaya T, Ibrahim F, Kim HJ, Mojsilovic-Petrovic J, Panossian S, Kim CE, Frackelton EC, Solski JA, Williams KL, Clay-Falcone D, et al. Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. Human Molecular Genetics. 21: 2899-911. PMID 22454397 DOI: 10.1093/Hmg/Dds116 |
0.785 |
|
| 2011 |
Couthouis J, Hart MP, Shorter J, DeJesus-Hernandez M, Erion R, Oristano R, Liu AX, Ramos D, Jethava N, Hosangadi D, Epstein J, Chiang A, Diaz Z, Nakaya T, Ibrahim F, et al. A yeast functional screen predicts new candidate ALS disease genes. Proceedings of the National Academy of Sciences of the United States of America. 108: 20881-90. PMID 22065782 DOI: 10.1073/Pnas.1109434108 |
0.783 |
|
| 2010 |
Couthouis J, Marchal C, D’Angelo F, Berthelot K, Cullin C. The toxicity of an "artificial" amyloid is related to how it interacts with membranes Prion. 4: 283-291. PMID 21057225 DOI: 10.4161/Pri.4.4.13126 |
0.333 |
|
| 2009 |
Couthouis J, Rébora K, Immel F, Berthelot K, Castroviejo M, Cullin C. Screening for Toxic Amyloid in Yeast Exemplifies the Role of Alternative Pathway Responsible for Cytotoxicity Plos One. 4: 4539. PMID 19262694 DOI: 10.1371/Journal.Pone.0004539 |
0.312 |
|
| Show low-probability matches. |