| Year |
Citation |
Score |
| 2023 |
Faleschini T, Syafni N, Schulte HL, Garifulina A, Hering S, Espindola LS, Hamburger M. A neolignan from Connarus tuberosus as an allosteric GABA receptor modulator at the neurosteroid binding site. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 161: 114498. PMID 36906973 DOI: 10.1016/j.biopha.2023.114498 |
0.505 |
|
| 2022 |
Heider J, Kilian J, Garifulina A, Hering S, Langer T, Seidel T. : A Versatile Workflow for the Generation of Receptor-based Pharmacophore Models for Virtual Screening. Journal of Chemical Information and Modeling. 63: 101-110. PMID 36526584 DOI: 10.1021/acs.jcim.2c00814 |
0.314 |
|
| 2022 |
Garifulina A, Friesacher T, Stadler M, Zangerl-Plessl EM, Ernst M, Stary-Weinzinger A, Willam A, Hering S. β subunits of GABA receptors form proton-gated chloride channels: Insights into the molecular basis. Communications Biology. 5: 784. PMID 35922471 DOI: 10.1038/s42003-022-03720-2 |
0.308 |
|
| 2022 |
Syafni N, Faleschini MT, Garifulina A, Danton O, Gupta MP, Hering S, Hamburger M. Clerodane Diterpenes from as Allosteric GABA Receptor Modulators. Journal of Natural Products. PMID 35475609 DOI: 10.1021/acs.jnatprod.1c00840 |
0.547 |
|
| 2019 |
Syafni N, Moradi-Afrapoli F, Danton O, Wilhelm A, Stadler M, Hering S, Potterat O, Hamburger M. HPLC-Based Activity Profiling for GABAA Receptor Modulators in Murraya exotica Natural Product Communications. 14: 1934578X1901400. DOI: 10.1177/1934578X1901400112 |
0.546 |
|
| 2018 |
Stadler M, Monticelli S, Seidel T, Luger D, Salzer I, Boehm S, Holzer W, Schwarzer C, Urban E, Khom S, Langer T, Pace V, Hering S. Design, synthesis and pharmacological evaluation of novel β2/3 subunit-selective γ-Aminobutyric Acid Type A (GABAA) receptor modulators. Journal of Medicinal Chemistry. PMID 30289721 DOI: 10.1021/acs.jmedchem.8b00859 |
0.762 |
|
| 2017 |
Moradi-Afrapoli F, van der Merwe H, De Mieri M, Wilhelm A, Stadler M, Zietsman PC, Hering S, Swart K, Hamburger M. HPLC-Based Activity Profiling for GABAA Receptor Modulators in Searsia pyroides Using a Larval Zebrafish Locomotor Assay. Planta Medica. PMID 28511229 DOI: 10.1055/s-0043-110768 |
0.374 |
|
| 2016 |
Khom S, Hintersteiner J, Luger D, Haider M, Pototschnig G, Mihovilovic MD, Schwarzer C, Hering S. Analysis of β-Subunit-dependent GABAA Receptor Modulation and Behavioral Effects of Valerenic Acid Derivatives. The Journal of Pharmacology and Experimental Therapeutics. 357: 580-90. PMID 27190170 DOI: 10.1124/jpet.116.232983 |
0.691 |
|
| 2015 |
Bernaskova M, Schoeffmann A, Schuehly W, Hufner A, Baburin I, Hering S. Nitrogenated honokiol derivatives allosterically modulate GABAA receptors and act as strong partial agonists. Bioorganic & Medicinal Chemistry. 23: 6757-62. PMID 26410663 DOI: 10.1016/j.bmc.2015.08.034 |
0.374 |
|
| 2015 |
Luger D, Poli G, Wieder M, Stadler M, Ke S, Ernst M, Hohaus A, Linder T, Seidel T, Langer T, Khom S, Hering S. Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site-directed mutagenesis. British Journal of Pharmacology. PMID 26375408 DOI: 10.1111/bph.13329 |
0.699 |
|
| 2015 |
Wimmer L, Schönbauer D, Pakfeifer P, Schöffmann A, Khom S, Hering S, Mihovilovic MD. Developing piperine towards TRPV1 and GABAA receptor ligands--synthesis of piperine analogs via Heck-coupling of conjugated dienes. Organic & Biomolecular Chemistry. 13: 990-4. PMID 25438036 DOI: 10.1039/c4ob02242d |
0.711 |
|
| 2014 |
Rueda DC, Raith M, De Mieri M, Schöffmann A, Hering S, Hamburger M. Identification of dehydroabietc acid from Boswellia thurifera resin as a positive GABAA receptor modulator. Fitoterapia. 99: 28-34. PMID 25200370 DOI: 10.1016/j.fitote.2014.09.002 |
0.491 |
|
| 2014 |
Strommer B, Khom S, Kastenberger I, Cicek SS, Stuppner H, Schwarzer C, Hering S. A cycloartane glycoside derived from Actaea racemosa L. modulates GABAA receptors and induces pronounced sedation in mice. The Journal of Pharmacology and Experimental Therapeutics. 351: 234-42. PMID 25161170 DOI: 10.1124/jpet.114.218024 |
0.757 |
|
| 2014 |
Schöffmann A, Wimmer L, Goldmann D, Khom S, Hintersteiner J, Baburin I, Schwarz T, Hintersteininger M, Pakfeifer P, Oufir M, Hamburger M, Erker T, Ecker GF, Mihovilovic MD, Hering S. Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives. Journal of Medicinal Chemistry. 57: 5602-19. PMID 24905252 DOI: 10.1021/Jm5002277 |
0.68 |
|
| 2014 |
Hintersteiner J, Haider M, Luger D, Schwarzer C, Reznicek G, Jäger W, Khom S, Mihovilovic MD, Hering S. Esters of valerenic acid as potential prodrugs. European Journal of Pharmacology. 735: 123-31. PMID 24680924 DOI: 10.1016/j.ejphar.2014.03.019 |
0.763 |
|
| 2014 |
Rueda DC, De Mieri M, Hering S, Hamburger M. HPLC-based activity profiling for GABAA receptor modulators in Adenocarpus cincinnatus. Journal of Natural Products. 77: 640-9. PMID 24571311 DOI: 10.1021/np500016z |
0.47 |
|
| 2014 |
Rueda DC, Schöffmann A, De Mieri M, Raith M, Jähne EA, Hering S, Hamburger M. Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators. Bioorganic & Medicinal Chemistry. 22: 1276-84. PMID 24462176 DOI: 10.1016/j.bmc.2014.01.008 |
0.568 |
|
| 2013 |
Schramm A, Ebrahimi SN, Raith M, Zaugg J, Rueda DC, Hering S, Hamburger M. Phytochemical profiling of Curcuma kwangsiensis rhizome extract, and identification of labdane diterpenoids as positive GABAA receptor modulators. Phytochemistry. 96: 318-29. PMID 24011802 DOI: 10.1016/j.phytochem.2013.08.004 |
0.408 |
|
| 2013 |
Khom S, Strommer B, Schöffmann A, Hintersteiner J, Baburin I, Erker T, Schwarz T, Schwarzer C, Zaugg J, Hamburger M, Hering S. GABAA receptor modulation by piperine and a non-TRPV1 activating derivative. Biochemical Pharmacology. 85: 1827-36. PMID 23623790 DOI: 10.1016/J.Bcp.2013.04.017 |
0.8 |
|
| 2013 |
Rueda D, de Mieri M, Hering S, Hamburger M. Isoflavonoid derivatives from Adenocarpus cincinnatus as positive GABAA receptor modulators Planta Medica. 79. DOI: 10.1055/S-0033-1352179 |
0.389 |
|
| 2013 |
Rueda D, Schöffmann A, de Mieri M, Raith M, Jähne E, Hering S, Hamburger M. Identification of dihydrostilbenes as a new scaffold for GABAA receptor modulators in Pholidota chinensis stems and roots Planta Medica. 79. DOI: 10.1055/s-0033-1351811 |
0.3 |
|
| 2012 |
Kim HJ, Baburin I, Zaugg J, Ebrahimi SN, Hering S, Hamburger M. HPLC-based activity profiling--discovery of sanggenons as GABAA receptor modulators in the traditional Chinese drug Sang bai pi (Morus alba root bark). Planta Medica. 78: 440-7. PMID 22294264 DOI: 10.1055/s-0031-1298229 |
0.575 |
|
| 2012 |
Rueda DC, Zaugg J, Quitschau M, Reich E, Hering S, Hamburger M. Discovery of GABA(A) receptor modulator aristolactone in a commercial sample of the Chinese herbal drug "Chaihu" (Bupleurum chinense roots) unravels adulteration by nephrotoxic Aristolochia manshuriensis roots. Planta Medica. 78: 207-10. PMID 22271081 DOI: 10.1055/s-0031-1298171 |
0.33 |
|
| 2012 |
Singhuber J, Baburin I, Khom S, Zehl M, Urban E, Hering S, Kopp B. GABA(A) receptor modulators from the Chinese herbal drug Junci Medulla--the pith of Juncus effusus. Planta Medica. 78: 455-8. PMID 22271080 DOI: 10.1055/s-0031-1298174 |
0.786 |
|
| 2012 |
Singhuber J, Baburin I, Kählig H, Urban E, Kopp B, Hering S. GABA(A) receptor modulators from Chinese herbal medicines traditionally applied against insomnia and anxiety. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 19: 334-40. PMID 22118921 DOI: 10.1016/j.phymed.2011.10.009 |
0.547 |
|
| 2011 |
Zaugg J, Ebrahimi SN, Smiesko M, Baburin I, Hering S, Hamburger M. Identification of GABA A receptor modulators in Kadsura longipedunculata and assignment of absolute configurations by quantum-chemical ECD calculations. Phytochemistry. 72: 2385-95. PMID 21889177 DOI: 10.1016/j.phytochem.2011.08.014 |
0.544 |
|
| 2011 |
Zaugg J, Khom S, Eigenmann D, Baburin I, Hamburger M, Hering S. Identification and characterization of GABA(A) receptor modulatory diterpenes from Biota orientalis that decrease locomotor activity in mice. Journal of Natural Products. 74: 1764-72. PMID 21793559 DOI: 10.1021/np200317p |
0.75 |
|
| 2011 |
Singhuber J, Baburin I, Ecker GF, Kopp B, Hering S. Insights into structure-activity relationship of GABAA receptor modulating coumarins and furanocoumarins. European Journal of Pharmacology. 668: 57-64. PMID 21749864 DOI: 10.1016/J.Ejphar.2011.06.034 |
0.415 |
|
| 2011 |
Taferner B, Schuehly W, Huefner A, Baburin I, Wiesner K, Ecker GF, Hering S. Modulation of GABAA-receptors by honokiol and derivatives: subtype selectivity and structure-activity relationship. Journal of Medicinal Chemistry. 54: 5349-61. PMID 21699169 DOI: 10.1021/Jm200186N |
0.366 |
|
| 2011 |
Zaugg J, Eickmeier E, Ebrahimi SN, Baburin I, Hering S, Hamburger M. Positive GABA(A) receptor modulators from Acorus calamus and structural analysis of (+)-dioxosarcoguaiacol by 1D and 2D NMR and molecular modeling. Journal of Natural Products. 74: 1437-43. PMID 21563811 DOI: 10.1021/np200181d |
0.393 |
|
| 2011 |
Yang X, Baburin I, Plitzko I, Hering S, Hamburger M. HPLC-based activity profiling for GABAA receptor modulators from the traditional Chinese herbal drug Kushen (Sophora flavescens root). Molecular Diversity. 15: 361-72. PMID 21207144 DOI: 10.1007/s11030-010-9297-7 |
0.572 |
|
| 2011 |
Zaugg J, Eickmeier E, Rueda DC, Hering S, Hamburger M. HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes. Fitoterapia. 82: 434-40. PMID 21147202 DOI: 10.1016/j.fitote.2010.12.001 |
0.586 |
|
| 2010 |
Cicek SS, Khom S, Taferner B, Hering S, Stuppner H. Bioactivity-guided isolation of GABA(A) receptor modulating constituents from the rhizomes of Actaea racemosa. Journal of Natural Products. 73: 2024-8. PMID 21082802 DOI: 10.1021/np100479w |
0.771 |
|
| 2010 |
Khom S, Strommer B, Ramharter J, Schwarz T, Schwarzer C, Erker T, Ecker GF, Mulzer J, Hering S. Valerenic acid derivatives as novel subunit-selective GABAA receptor ligands - in vitro and in vivo characterization. British Journal of Pharmacology. 161: 65-78. PMID 20718740 DOI: 10.1111/J.1476-5381.2010.00865.X |
0.793 |
|
| 2010 |
Li Y, Plitzko I, Zaugg J, Hering S, Hamburger M. HPLC-based activity profiling for GABA(A) receptor modulators: a new dihydroisocoumarin from Haloxylon scoparium. Journal of Natural Products. 73: 768-70. PMID 20210326 DOI: 10.1021/np900803w |
0.554 |
|
| 2010 |
Zaugg J, Baburin I, Strommer B, Kim H, Hering S, Hamburger M. HPLC-Based Activity Profiling: Discovery of Piperine as a Positive GABAA Receptor Modulator Targeting a Benzodiazepine-Independent Binding Site Journal of Natural Products. 73: 185-191. PMID 20085307 DOI: 10.1021/Np900656G |
0.467 |
|
| 2010 |
Rueda D, Zaugg J, Hering S, Hamburger M. Identification of γ-aminobutyric acid type A (GABAA) receptor modulators: HPLC-based activity profiling of Asarum heterotropoides Planta Medica. 76. DOI: 10.1055/S-0030-1264920 |
0.449 |
|
| 2009 |
Baburin I, Khom S, Timin E, Hohaus A, Sieghart W, Hering S. Benzodiazepines modulate GABAA receptors by reducing a gamma-subunit-mediated inhibition of GABA sensitivity Bmc Pharmacology. 9: A23. DOI: 10.1186/1471-2210-9-S2-A23 |
0.768 |
|
| 2009 |
Zaugg J, Baburin I, Hering S, Hamburger M. Identifying GABAA receptor ligands in black pepper by activity profiling, LC-TOFMS, and offline microprobe NMR Planta Medica. 75. DOI: 10.1055/S-0029-1234276 |
0.317 |
|
| 2008 |
Baburin I, Khom S, Timin E, Hohaus A, Sieghart W, Hering S. Estimating the efficiency of benzodiazepines on GABA(A) receptors comprising gamma1 or gamma2 subunits. British Journal of Pharmacology. 155: 424-33. PMID 18604239 DOI: 10.1038/bjp.2008.271 |
0.768 |
|
| 2008 |
Kim HJ, Baburin I, Khom S, Hering S, Hamburger M. HPLC-based activity profiling approach for the discovery of GABAA receptor ligands using an automated two microelectrode voltage clamp assay on Xenopus oocytes. Planta Medica. 74: 521-6. PMID 18543148 DOI: 10.1055/s-2008-1074491 |
0.76 |
|
| 2008 |
Trauner G, Khom S, Baburin I, Benedek B, Hering S, Kopp B. Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid. Planta Medica. 74: 19-24. PMID 18095218 DOI: 10.1055/s-2007-993761 |
0.733 |
|
| 2007 |
Khom S, Baburin I, Timin E, Hohaus A, Trauner G, Kopp B, Hering S. Valerenic acid potentiates and inhibits GABA(A) receptors: molecular mechanism and subunit specificity. Neuropharmacology. 53: 178-87. PMID 17585957 DOI: 10.1016/j.neuropharm.2007.04.018 |
0.754 |
|
| 2007 |
Kim H, Khom S, Baburin I, Hering S, Hamburger M. HPLC-based activity profiling of plant and fungal extracts for GABAA receptor ligands using a functional assay with Xenopus oocytes Planta Medica. 73. DOI: 10.1055/s-2007-986720 |
0.679 |
|
| 2006 |
Khom S, Baburin I, Timin EN, Hohaus A, Sieghart W, Hering S. Pharmacological properties of GABAA receptors containing gamma1 subunits. Molecular Pharmacology. 69: 640-9. PMID 16272224 DOI: 10.1124/mol.105.017236 |
0.749 |
|
| 2006 |
Brattström A, Baburin I, Khom S, Hering S, Koetter U. Valerian extract modulates the GABAA-action on its receptors Planta Medica. 72. DOI: 10.1055/S-2006-950024 |
0.72 |
|
| 2006 |
Trauner G, Khom S, Benedek B, Hering S, Kopp B. Identification of GABAA-modulators obtained from Valeriana officinalis L Planta Medica. 72. DOI: 10.1055/S-2006-949848 |
0.628 |
|
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