Frederick Livesey - Publications

Affiliations: 
University of Cambridge, Cambridge, England, United Kingdom 
Area:
Cortical development
Website:
http://www.gurdon.cam.ac.uk/~liveseylab/fjlhome/index.html

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 St George-Hyslop F, Haneklaus M, Kivisild T, Livesey FJ. Loss of CNTNAP2 alters human cortical excitatory neuron differentiation and neural network development. Biological Psychiatry. PMID 37001843 DOI: 10.1016/j.biopsych.2023.03.014  0.305
2022 Ampartzidis I, Efstathiou C, Paonessa F, Thompson EM, Wilson T, McCann CJ, Greene N, Copp AJ, Livesey FJ, Elvassore N, Giobbe GG, De Coppi P, Maniou E, Galea GL. Synchronisation of apical constriction and cell cycle progression is a conserved behaviour of pseudostratified neuroepithelia informed by their tissue geometry. Developmental Biology. PMID 36509125 DOI: 10.1016/j.ydbio.2022.12.002  0.327
2021 Hung C, Livesey FJ. Endolysosome and autophagy dysfunction in Alzheimer disease. Autophagy. 1-2. PMID 34429033 DOI: 10.1080/15548627.2021.1963630  0.316
2020 Strano A, Tuck E, Stubbs VE, Livesey FJ. Variable Outcomes in Neural Differentiation of Human PSCs Arise from Intrinsic Differences in Developmental Signaling Pathways. Cell Reports. 31: 107732. PMID 32521257 DOI: 10.1016/j.celrep.2020.107732  0.396
2019 Krieger TG, Moran CM, Frangini A, Visser WE, Schoenmakers E, Muntoni F, Clark CA, Gadian D, Chong WK, Kuczynski A, Dattani M, Lyons G, Efthymiadou A, Varga-Khadem F, Simons BD, ... ... Livesey FJ, et al. Mutations in thyroid hormone receptor α1 cause premature neurogenesis and progenitor cell depletion in human cortical development. Proceedings of the National Academy of Sciences of the United States of America. PMID 31628250 DOI: 10.1073/Pnas.1908762116  0.4
2018 Real R, Peter M, Trabalza A, Khan S, Smith MA, Dopp J, Barnes SJ, Momoh A, Strano A, Volpi E, Knott G, Livesey FJ, De Paola V. In vivo modeling of human neuron dynamics and Down syndrome. Science (New York, N.Y.). PMID 30309905 DOI: 10.1126/science.aau1810  0.341
2018 Brownjohn PW, Smith J, Solanki R, Lohmann E, Houlden H, Hardy J, Dietmann S, Livesey FJ. Functional Studies of Missense TREM2 Mutations in Human Stem Cell-Derived Microglia. Stem Cell Reports. PMID 29606617 DOI: 10.1016/J.Stemcr.2018.03.003  0.323
2017 Brownjohn PW, Smith J, Portelius E, Serneels L, Kvartsberg H, De Strooper B, Blennow K, Zetterberg H, Livesey FJ. Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer's Disease. Stem Cell Reports. PMID 28285880 DOI: 10.1016/j.stemcr.2017.02.006  0.309
2016 Otani T, Marchetto MC, Gage FH, Simons BD, Livesey FJ. 2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size. Cell Stem Cell. 18: 467-80. PMID 27049876 DOI: 10.1016/J.Stem.2016.03.003  0.397
2016 Saurat NG, Livesey FJ, Moore S. Cortical Differentiation of Human Pluripotent Cells for In Vitro Modeling of Alzheimer's Disease. Methods in Molecular Biology (Clifton, N.J.). 1303: 267-78. PMID 26235073 DOI: 10.1007/978-1-4939-2627-5_16  0.774
2016 Saurat NG, Livesey FJ, Moore S. Cortical differentiation of human pluripotent cells for in vitro modeling of Alzheimer’s disease Methods in Molecular Biology. 1303: 267-278. DOI: 10.1007/978-1-4939-2627-5_16  0.755
2015 Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, et al. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. PMID 26610635 DOI: 10.1016/J.Stemcr.2015.10.011  0.603
2015 Kirwan P, Turner-Bridger B, Peter M, Momoh A, Arambepola D, Robinson HP, Livesey FJ. Development and function of human cerebral cortex neural networks from pluripotent stem cells in vitro. Development (Cambridge, England). 142: 3178-87. PMID 26395144 DOI: 10.1242/Dev.123851  0.589
2015 Sposito T, Preza E, Mahoney CJ, Setó-Salvia N, Ryan NS, Morris HR, Arber C, Devine MJ, Houlden H, Warner TT, Bushell TJ, Zagnoni M, Kunath T, Livesey FJ, Fox NC, et al. Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT. Human Molecular Genetics. PMID 26136155 DOI: 10.1093/Hmg/Ddv246  0.36
2015 Knock E, Pereira J, Lombard PD, Dimond A, Leaford D, Livesey FJ, Hendrich B. The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Development. 10: 13. PMID 25934499 DOI: 10.1186/S13064-015-0040-Z  0.455
2015 Moore S, Evans LD, Andersson T, Portelius E, Smith J, Dias TB, Saurat N, McGlade A, Kirwan P, Blennow K, Hardy J, Zetterberg H, Livesey FJ. APP metabolism regulates tau proteostasis in human cerebral cortex neurons. Cell Reports. 11: 689-96. PMID 25921538 DOI: 10.1016/J.Celrep.2015.03.068  0.71
2015 Macaulay IC, Haerty W, Kumar P, Li YI, Hu TX, Teng MJ, Goolam M, Saurat N, Coupland P, Shirley LM, Smith M, Van der Aa N, Banerjee R, Ellis PD, Quail MA, ... ... Livesey FJ, et al. G&T-seq: parallel sequencing of single-cell genomes and transcriptomes. Nature Methods. 12: 519-22. PMID 25915121 DOI: 10.1038/Nmeth.3370  0.712
2015 Medvinsky A, Livesey FJ. On human development: lessons from stem cell systems. Development (Cambridge, England). 142: 17-20. PMID 25516966 DOI: 10.1242/dev.114868  0.359
2014 Livesey FJ. Human stem cell models of dementia. Human Molecular Genetics. 23: R35-9. PMID 24939911 DOI: 10.1093/hmg/ddu302  0.34
2014 Ali FR, Cheng K, Kirwan P, Metcalfe S, Livesey FJ, Barker RA, Philpott A. The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro. Development (Cambridge, England). 141: 2216-24. PMID 24821983 DOI: 10.1242/Dev.106377  0.631
2013 Saurat N, Andersson T, Vasistha NA, Molnár Z, Livesey FJ. Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development. Neural Development. 8: 14. PMID 23895693 DOI: 10.1186/1749-8104-8-14  0.765
2013 Mi D, Carr CB, Georgala PA, Huang YT, Manuel MN, Jeanes E, Niisato E, Sansom SN, Livesey FJ, Theil T, Hasenpusch-Theil K, Simpson TI, Mason JO, Price DJ. Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb. Neuron. 78: 269-84. PMID 23622063 DOI: 10.1016/J.Neuron.2013.02.012  0.307
2013 Alsiö JM, Tarchini B, Cayouette M, Livesey FJ. Ikaros promotes early-born neuronal fates in the cerebral cortex. Proceedings of the National Academy of Sciences of the United States of America. 110: E716-25. PMID 23382203 DOI: 10.1073/Pnas.1215707110  0.384
2012 Livesey FJ. Stem cell models of Alzheimer's disease and related neurological disorders. Alzheimer's Research & Therapy. 4: 44. PMID 23131128 DOI: 10.1186/alzrt147  0.301
2012 Livesey FJ. A potential link between obesity and neural stem cell dysfunction. Nature Cell Biology. 14: 987-9. PMID 23033050 DOI: 10.1038/ncb2599  0.326
2012 Shi Y, Kirwan P, Livesey FJ. Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks. Nature Protocols. 7: 1836-46. PMID 22976355 DOI: 10.1038/Nprot.2012.116  0.685
2012 Shi Y, Kirwan P, Smith J, MacLean G, Orkin SH, Livesey FJ. A human stem cell model of early Alzheimer's disease pathology in Down syndrome. Science Translational Medicine. 4: 124ra29. PMID 22344463 DOI: 10.1126/Scitranslmed.3003771  0.645
2012 Shi Y, Kirwan P, Smith J, Robinson HP, Livesey FJ. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nature Neuroscience. 15: 477-86, S1. PMID 22306606 DOI: 10.1038/Nn.3041  0.673
2011 Brand AH, Livesey FJ. Neural stem cell biology in vertebrates and invertebrates: more alike than different? Neuron. 70: 719-29. PMID 21609827 DOI: 10.1016/J.Neuron.2011.05.016  0.375
2010 Andersson T, Rahman S, Sansom SN, Alsiö JM, Kaneda M, Smith J, O'Carroll D, Tarakhovsky A, Livesey FJ. Reversible block of mouse neural stem cell differentiation in the absence of dicer and microRNAs. Plos One. 5: e13453. PMID 20976144 DOI: 10.1371/journal.pone.0013453  0.695
2010 Pereira JD, Sansom SN, Smith J, Dobenecker MW, Tarakhovsky A, Livesey FJ. Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Proceedings of the National Academy of Sciences of the United States of America. 107: 15957-62. PMID 20798045 DOI: 10.1073/pnas.1002530107  0.396
2010 Subkhankulova T, Yano K, Robinson HP, Livesey FJ. Grouping and classifying electrophysiologically-defined classes of neocortical neurons by single cell, whole-genome expression profiling. Frontiers in Molecular Neuroscience. 3: 10. PMID 20428506 DOI: 10.3389/fnmol.2010.00010  0.349
2009 Sansom SN, Livesey FJ. Gradients in the brain: the control of the development of form and function in the cerebral cortex. Cold Spring Harbor Perspectives in Biology. 1: a002519. PMID 20066088 DOI: 10.1101/cshperspect.a002519  0.332
2009 Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ. The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. Plos Genetics. 5: e1000511. PMID 19521500 DOI: 10.1371/journal.pgen.1000511  0.407
2008 Subkhankulova T, Gilchrist MJ, Livesey FJ. Modelling and measuring single cell RNA expression levels find considerable transcriptional differences among phenotypically identical cells. Bmc Genomics. 9: 268. PMID 18522723 DOI: 10.1186/1471-2164-9-268  0.334
2006 Yano K, Subkhankulova T, Livesey FJ, Robinson HP. Electrophysiological and gene expression profiling of neuronal cell types in mammalian neocortex. The Journal of Physiology. 575: 361-5. PMID 16840515 DOI: 10.1113/jphysiol.2006.113712  0.372
2005 Sansom SN, Hébert JM, Thammongkol U, Smith J, Nisbet G, Surani MA, McConnell SK, Livesey FJ. Genomic characterisation of a Fgf-regulated gradient-based neocortical protomap. Development (Cambridge, England). 132: 3947-61. PMID 16079153 DOI: 10.1242/dev.01968  0.322
2005 Brand AH, Livesey FJ. Cell differentiation: Editorial overview Current Opinion in Cell Biology. 17: 637-638. DOI: 10.1016/J.Ceb.2005.10.007  0.353
2004 Perry P, Sauer S, Billon N, Richardson WD, Spivakov M, Warnes G, Livesey FJ, Merkenschlager M, Fisher AG, Azuara V. A dynamic switch in the replication timing of key regulator genes in embryonic stem cells upon neural induction. Cell Cycle (Georgetown, Tex.). 3: 1645-50. PMID 15611653 DOI: 10.4161/Cc.3.12.1346  0.364
2004 Robinson M, Parsons Perez MC, Tébar L, Palmer J, Patel A, Marks D, Sheasby A, De Felipe C, Coffin R, Livesey FJ, Hunt SP. FLRT3 is expressed in sensory neurons after peripheral nerve injury and regulates neurite outgrowth. Molecular and Cellular Neurosciences. 27: 202-14. PMID 15485775 DOI: 10.1016/j.mcn.2004.06.008  0.504
2004 Livesey FJ, Young TL, Cepko CL. An analysis of the gene expression program of mammalian neural progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 1374-9. PMID 14734810 DOI: 10.1073/pnas.0307014101  0.606
2003 Dyer MA, Livesey FJ, Cepko CL, Oliver G. Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nature Genetics. 34: 53-8. PMID 12692551 DOI: 10.1038/ng1144  0.668
2001 Livesey FJ, Hunt SP. Differential display of mRNA by PCR. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 11.5. PMID 18428247 DOI: 10.1002/0471142905.hg1105s10  0.471
2001 Livesey FJ, Cepko CL. Vertebrate neural cell-fate determination: lessons from the retina. Nature Reviews. Neuroscience. 2: 109-18. PMID 11252990 DOI: 10.1038/35053522  0.585
2000 Livesey FJ, Furukawa T, Steffen MA, Church GM, Cepko CL. Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene Crx. Current Biology : Cb. 10: 301-10. PMID 10744971 DOI: 10.1016/S0960-9822(00)00379-1  0.5
1999 Livesey F, Gustincich S, Steffen M, Cheung V, Raviola E, Church G, Cepko C. Clustering cell types and identifying cell-type specific transcripts by gene expression profiling in single neurons Nature Genetics. 23: 59-59. DOI: 10.1038/14354  0.55
1998 Livesey FJ, Hunt SP. Differential display cloning of genes induced in regenerating neurons. Methods (San Diego, Calif.). 16: 386-95. PMID 10049646 DOI: 10.1006/meth.1998.0693  0.509
1997 Livesey FJ, O'Brien JA, Li M, Smith AG, Murphy LJ, Hunt SP. A Schwann cell mitogen accompanying regeneration of motor neurons. Nature. 390: 614-8. PMID 9403691 DOI: 10.1038/37615  0.511
1997 Livesey FJ, Hunt SP. Netrin and netrin receptor expression in the embryonic mammalian nervous system suggests roles in retinal, striatal, nigral, and cerebellar development. Molecular and Cellular Neurosciences. 8: 417-29. PMID 9143559 DOI: 10.1006/mcne.1997.0598  0.475
1996 Livesey FJ, Hunt SP. Identifying changes in gene expression in the nervous system: mRNA differential display. Trends in Neurosciences. 19: 84-8. PMID 9054059 DOI: 10.1016/S0166-2236(96)80032-4  0.472
1996 Thomas KL, Livesey FJ, Hunt SP, Bliss TVP. Identifying changes in gene expression during long-term potentiation using differential display analysis Journal of Physiology Paris. 90: 429-430.  0.435
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