Akihiro Yamanaka, Ph.D. - Publications

Affiliations: 
Nagoya University, Nagoya-shi, Aichi-ken, Japan 

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Yamaguchi H, Murphy KR, Fukatsu N, Sato K, Yamanaka A, de Lecea L. Dorsomedial and preoptic hypothalamic circuits control torpor. Current Biology : Cb. PMID 37992720 DOI: 10.1016/j.cub.2023.10.076  0.305
2023 Mukai Y, Okubo TS, Lazarus M, Ono D, Tanaka KF, Yamanaka A. Prostaglandin E Induces Long-Lasting Inhibition of Noradrenergic Neurons in the Locus Coeruleus and Moderates the Behavioral Response to Stressors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 43: 7982-7999. PMID 37734949 DOI: 10.1523/JNEUROSCI.0353-23.2023  0.396
2023 Li WR, Nakano T, Mizutani K, Matsubara T, Kawatani M, Mukai Y, Danjo T, Ito H, Aizawa H, Yamanaka A, Petersen CCH, Yoshimoto J, Yamashita T. Neural mechanisms underlying uninstructed orofacial movements during reward-based learning behaviors. Current Biology : Cb. 33: 3436-3451.e7. PMID 37536343 DOI: 10.1016/j.cub.2023.07.013  0.787
2023 Miyazaki T, Chowdhury S, Yamashita T, Matsubara T, Yawo H, Yuasa H, Yamanaka A. Retraction Notice to: Large Timescale Interrogation of Neuronal Function by Fiberless Optogenetics Using Lanthanide Micro-particles. Cell Reports. 42: 112564. PMID 37204927 DOI: 10.1016/j.celrep.2023.112564  0.774
2023 Hung C, Yamanaka A. The role of orexin neuron activity in sleep/wakefulness regulation. Peptides. 165: 171007. PMID 37030519 DOI: 10.1016/j.peptides.2023.171007  0.403
2023 Mukai Y, Li Y, Nakamura A, Fukatsu N, Iijima D, Abe M, Sakimura K, Itoi K, Yamanaka A. Cre-dependent ACR2-expressing reporter mouse strain for efficient long-lasting inhibition of neuronal activity. Scientific Reports. 13: 3966. PMID 36894577 DOI: 10.1038/s41598-023-30907-2  0.34
2022 Rahaman SM, Chowdhury S, Mukai Y, Ono D, Yamaguchi H, Yamanaka A. Functional Interaction Between GABAergic Neurons in the Ventral Tegmental Area and Serotonergic Neurons in the Dorsal Raphe Nucleus. Frontiers in Neuroscience. 16: 877054. PMID 35663550 DOI: 10.3389/fnins.2022.877054  0.827
2022 Matsubara T, Yanagida T, Kawaguchi N, Nakano T, Yoshimoto J, Sezaki M, Takizawa H, Tsunoda SP, Horigane SI, Ueda S, Takemoto-Kimura S, Kandori H, Yamanaka A, Yamashita T. Author Correction: Remote control of neural function by X-ray-induced scintillation. Nature Communications. 13: 1950. PMID 35388020 DOI: 10.1038/s41467-022-29664-z  0.744
2022 Hung CJ, Yamanaka A, Ono D. Conditional Knockout of in Corticotropin-Releasing Factor Neurons Does Not Alter Sleep-Wake Rhythm in Mice. Frontiers in Neuroscience. 15: 808754. PMID 35250437 DOI: 10.3389/fnins.2021.808754  0.39
2022 Zhou S, Yamashita A, Su J, Zhang Y, Wang W, Hao L, Yamanaka A, Kuwaki T. Activity of putative orexin neurons during cataplexy. Molecular Brain. 15: 21. PMID 35246205 DOI: 10.1186/s13041-022-00907-w  0.393
2021 Kawatani M, de Groat WC, Itoi K, Uchida K, Sakimura K, Yamanaka A, Yamashita T, Kawatani M. Downstream projection of Barrington's nucleus to the spinal cord in mice. Journal of Neurophysiology. 126: 1959-1977. PMID 34731061 DOI: 10.1152/jn.00026.2021  0.554
2021 Moriya R, Kanamaru M, Okuma N, Yoshikawa A, Tanaka KF, Hokari S, Ohshima Y, Yamanaka A, Honma M, Onimaru H, Kikuchi T, Izumizaki M. Optogenetic activation of DRN 5-HT neurons induced active wakefulness, not quiet wakefulness. Brain Research Bulletin. 177: 129-142. PMID 34563634 DOI: 10.1016/j.brainresbull.2021.09.019  0.351
2021 Matsubara T, Yanagida T, Kawaguchi N, Nakano T, Yoshimoto J, Sezaki M, Takizawa H, Tsunoda SP, Horigane SI, Ueda S, Takemoto-Kimura S, Kandori H, Yamanaka A, Yamashita T. Remote control of neural function by X-ray-induced scintillation. Nature Communications. 12: 4478. PMID 34294698 DOI: 10.1038/s41467-021-24717-1  0.772
2021 Yamashita A, Moriya S, Nishi R, Kaminosono J, Yamanaka A, Kuwaki T. Aversive emotion rapidly activates orexin neurons and increases heart rate in freely moving mice. Molecular Brain. 14: 104. PMID 34193206 DOI: 10.1186/s13041-021-00818-2  0.359
2021 Izawa S, Yoneshiro T, Kondoh K, Nakagiri S, Okamatsu-Ogura Y, Terao A, Minokoshi Y, Yamanaka A, Kimura K. Melanin-concentrating hormone-producing neurons in the hypothalamus regulate brown adipose tissue and thus contribute to energy expenditure. The Journal of Physiology. PMID 33899241 DOI: 10.1113/JP281241  0.353
2021 Ohmura Y, Iwami K, Chowdhury S, Sasamori H, Sugiura C, Bouchekioua Y, Nishitani N, Yamanaka A, Yoshioka M. Disruption of model-based decision making by silencing of serotonin neurons in the dorsal raphe nucleus. Current Biology : Cb. PMID 33838101 DOI: 10.1016/j.cub.2021.03.048  0.771
2021 Chowdhury S, Yamanaka A. Fiberless Optogenetics. Advances in Experimental Medicine and Biology. 1293: 407-416. PMID 33398829 DOI: 10.1007/978-981-15-8763-4_26  0.778
2021 Horii-Hayashi N, Nomoto K, Endo N, Yamanaka A, Kikusui T, Nishi M. Hypothalamic perifornical Urocortin-3 neurons modulate defensive responses to a potential threat stimulus. Iscience. 24: 101908. PMID 33385113 DOI: 10.1016/j.isci.2020.101908  0.302
2020 Setsu T, Hamada Y, Oikawa D, Mori T, Ishiuji Y, Sato D, Narita M, Miyazaki S, Furuta E, Suda Y, Sakai H, Ochiya T, Tezuka H, Iseki M, Inada E, ... Yamanaka A, et al. Direct evidence that the brain reward system is involved in the control of scratching behaviors induced by acute and chronic itch. Biochemical and Biophysical Research Communications. PMID 33220930 DOI: 10.1016/j.bbrc.2020.11.030  0.33
2020 Ono D, Mukai Y, Hung CJ, Chowdhury S, Sugiyama T, Yamanaka A. The mammalian circadian pacemaker regulates wakefulness via CRF neurons in the paraventricular nucleus of the hypothalamus. Science Advances. 6. PMID 33158870 DOI: 10.1126/sciadv.abd0384  0.825
2020 Mukai Y, Nagayama A, Itoi K, Yamanaka A. Identification of substances which regulate activity of corticotropin-releasing factor-producing neurons in the paraventricular nucleus of the hypothalamus. Scientific Reports. 10: 13639. PMID 32788592 DOI: 10.1038/S41598-020-70481-5  0.473
2020 Kojima K, Miyoshi N, Shibukawa A, Chowdhury S, Tsujimura M, Noji T, Ishikita H, Yamanaka A, Sudo Y. Green-Sensitive, Long-Lived, Step-Functional Anion Channelrhodopsin-2 Variant as a High-Potential Neural Silencing Tool. The Journal of Physical Chemistry Letters. 6214-6218. PMID 32697087 DOI: 10.1021/Acs.Jpclett.0C01406  0.753
2020 Yoshida K, Tsutsui-Kimura I, Kono A, Yamanaka A, Kobayashi K, Watanabe M, Mimura M, Tanaka KF. Opposing Ventral Striatal Medium Spiny Neuron Activities Shaped by Striatal Parvalbumin-Expressing Interneurons during Goal-Directed Behaviors. Cell Reports. 31: 107829. PMID 32610130 DOI: 10.1016/J.Celrep.2020.107829  0.399
2020 Hung CJ, Ono D, Kilduff TS, Yamanaka A. Dual orexin and MCH neuron-ablated mice display severe sleep attacks and cataplexy. Elife. 9. PMID 32314734 DOI: 10.7554/Elife.54275  0.5
2020 Moriya S, Yamashita A, Masukawa D, Setoyama H, Hwang Y, Yamanaka A, Kuwaki T. Involvement of A13 dopaminergic neurons located in the zona incerta in nociceptive processing: a fiber photometry study. Molecular Brain. 13: 60. PMID 32290851 DOI: 10.1186/S13041-020-00600-W  0.36
2020 Flanigan ME, Aleyasin H, Li L, Burnett CJ, Chan KL, LeClair KB, Lucas EK, Matikainen-Ankney B, Durand-de Cuttoli R, Takahashi A, Menard C, Pfau ML, Golden SA, Bouchard S, Calipari ES, ... ... Yamanaka A, et al. Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice. Nature Neuroscience. PMID 32284606 DOI: 10.1038/S41593-020-0617-7  0.461
2020 Nagai Y, Takayama K, Nishitani N, Andoh C, Koda M, Shirakawa H, Nakagawa T, Nagayasu K, Yamanaka A, Kaneko S. The Role of Dorsal Raphe Serotonin Neurons in the Balance between Reward and Aversion. International Journal of Molecular Sciences. 21. PMID 32245184 DOI: 10.3390/Ijms21062160  0.427
2020 Imayoshi I, Tabuchi S, Matsumoto M, Kitano S, Miyachi H, Kageyama R, Yamanaka A. Light-induced silencing of neural activity in Rosa26 knock-in and BAC transgenic mice conditionally expressing the microbial halorhodopsin eNpHR3. Scientific Reports. 10: 3191. PMID 32081938 DOI: 10.1038/S41598-020-59984-3  0.441
2020 Moriya S, Yamashita A, Masukawa D, Kambe Y, Sakaguchi J, Setoyama H, Yamanaka A, Kuwaki T. Involvement of supralemniscal nucleus (B9) 5-HT neuronal system in nociceptive processing: a fiber photometry study. Molecular Brain. 13: 14. PMID 32005128 DOI: 10.1186/S13041-020-0553-1  0.355
2020 Hung CJ, Ono D, Kilduff TS, Yamanaka A. Author response: Dual orexin and MCH neuron-ablated mice display severe sleep attacks and cataplexy Elife. DOI: 10.7554/Elife.54275.Sa2  0.455
2019 Williams RH, Tsunematsu T, Thomas AM, Bogyo K, Yamanaka A, Kilduff TS. Transgenic Archaerhodopsin-3 Expression in Hypocretin/Orexin Neurons Engenders Cellular Dysfunction and Features of Type 2 Narcolepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31628177 DOI: 10.1523/Jneurosci.0311-19.2019  0.506
2019 Izawa S, Chowdhury S, Miyazaki T, Mukai Y, Ono D, Inoue R, Ohmura Y, Mizoguchi H, Kimura K, Yoshioka M, Terao A, Kilduff TS, Yamanaka A. REM sleep-active MCH neurons are involved in forgetting hippocampus-dependent memories. Science (New York, N.Y.). 365: 1308-1313. PMID 31604241 DOI: 10.1126/Science.Aax9238  0.813
2019 Matsubara T, Hayashi K, Wakatsuki K, Abe M, Ozaki N, Yamanaka A, Mizumura K, Taguchi T. Thin-fibre receptors expressing acid-sensing ion channel 3 contribute to muscular mechanical hypersensitivity after exercise. European Journal of Pain (London, England). PMID 31314951 DOI: 10.1002/Ejp.1454  0.749
2019 Ohmura Y, Tsutsui-Kimura I, Sasamori H, Nebuka M, Nishitani N, Tanaka KF, Yamanaka A, Yoshioka M. Different roles of distinct serotonergic pathways in anxiety-like behavior, antidepressant-like, and anti-impulsive effects. Neuropharmacology. 107703. PMID 31299228 DOI: 10.1016/J.Neuropharm.2019.107703  0.316
2019 Nishitani N, Ohmura Y, Nagayasu K, Shibui N, Kaneko S, Ohashi A, Yoshida T, Yamanaka A, Yoshioka M. CRISPR/Cas9-mediated in vivo gene editing reveals that neuronal 5-HT receptors in the dorsal raphe nucleus contribute to body temperature regulation in mice. Brain Research. PMID 31194947 DOI: 10.1016/J.Brainres.2019.06.009  0.356
2019 Moriya S, Yamashita A, Nishi R, Ikoma Y, Yamanaka A, Kuwaki T. Acute nociceptive stimuli rapidly induce the activity of serotonin and noradrenalin neurons in the brain stem of awake mice. Ibro Reports. 7: 1-9. PMID 31194165 DOI: 10.1016/J.Ibror.2019.05.005  0.454
2019 Chowdhury S, Matsubara T, Miyazaki T, Ono D, Fukatsu N, Abe M, Sakimura K, Sudo Y, Yamanaka A. GABA neurons in the ventral tegmental area regulate non-rapid eye movement sleep in mice. Elife. 8. PMID 31159923 DOI: 10.7554/Elife.44928  0.763
2019 Chowdhury S, Hung CJ, Izawa S, Inutsuka A, Kawamura M, Kawashima T, Bito H, Imayoshi I, Abe M, Sakimura K, Yamanaka A. Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice. Elife. 8. PMID 31159922 DOI: 10.7554/Elife.44927  0.824
2019 Yamanashi T, Maki M, Kojima K, Shibukawa A, Tsukamoto T, Chowdhury S, Yamanaka A, Takagi S, Sudo Y. Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination. Scientific Reports. 9: 7863. PMID 31133660 DOI: 10.1038/S41598-019-44308-X  0.773
2019 Murata K, Kinoshita T, Fukazawa Y, Kobayashi K, Yamanaka A, Hikida T, Manabe H, Yamaguchi M. Opposing Roles of Dopamine Receptor D1- and D2-Expressing Neurons in the Anteromedial Olfactory Tubercle in Acquisition of Place Preference in Mice. Frontiers in Behavioral Neuroscience. 13: 50. PMID 30930757 DOI: 10.3389/Fnbeh.2019.00050  0.417
2019 Liang L, Teh DBL, Dinh ND, Chen W, Chen Q, Wu Y, Chowdhury S, Yamanaka A, Sum TC, Chen CH, Thakor NV, All AH, Liu X. Upconversion amplification through dielectric superlensing modulation. Nature Communications. 10: 1391. PMID 30918264 DOI: 10.1038/S41467-019-09345-0  0.743
2019 Macpherson T, Mizoguchi H, Yamanaka A, Hikida T. Preproenkephalin-expressing ventral pallidal neurons control inhibitory avoidance learning. Neurochemistry International. PMID 30797970 DOI: 10.1016/J.Neuint.2019.02.011  0.419
2019 Zhang T, Yanagida J, Kamii H, Wada S, Domoto M, Sasase H, Deyama S, Takarada T, Hinoi E, Sakimura K, Yamanaka A, Maejima T, Mieda M, Sakurai T, Nishitani N, et al. Glutamatergic neurons in the medial prefrontal cortex mediate the formation and retrieval of cocaine-associated memories in mice. Addiction Biology. PMID 30734456 DOI: 10.1111/Adb.12723  0.388
2019 Miyazaki T, Chowdhury S, Yamashita T, Matsubara T, Yawo H, Yuasa H, Yamanaka A. Large Timescale Interrogation of Neuronal Function by Fiberless Optogenetics Using Lanthanide Micro-particles. Cell Reports. 26: 1033-1043.e5. PMID 30673599 DOI: 10.1016/J.Celrep.2019.01.001  0.776
2019 Chowdhury S, Matsubara T, Miyazaki T, Ono D, Fukatsu N, Abe M, Sakimura K, Sudo Y, Yamanaka A. Author response: GABA neurons in the ventral tegmental area regulate non-rapid eye movement sleep in mice Elife. DOI: 10.7554/Elife.44928.037  0.794
2019 Chowdhury S, Hung CJ, Izawa S, Inutsuka A, Kawamura M, Kawashima T, Bito H, Imayoshi I, Abe M, Sakimura K, Yamanaka A. Author response: Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice Elife. DOI: 10.7554/Elife.44927.026  0.806
2019 Hung CJ, Ono D, Yamanaka A. Orexin- and MCH-Neurons Double-Ablated Mice Display Severe Sleep Attacks and Cataplexy Ibro Reports. 6. DOI: 10.2139/Ssrn.3363761  0.509
2018 Matsui S, Sasaki T, Kohno D, Yaku K, Inutsuka A, Yokota-Hashimoto H, Kikuchi O, Suga T, Kobayashi M, Yamanaka A, Harada A, Nakagawa T, Onaka T, Kitamura T. Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice. Nature Communications. 9: 4604. PMID 30389922 DOI: 10.1038/S41467-018-07033-Z  0.439
2018 Heiss JE, Yamanaka A, Kilduff TS. Parallel Arousal Pathways in the Lateral Hypothalamus. Eneuro. 5. PMID 30225361 DOI: 10.1523/ENEURO.0228-18.2018  0.426
2018 Kondo T, Saito R, Otaka M, Yoshino-Saito K, Yamanaka A, Yamamori T, Watakabe A, Mizukami H, Schnitzer MJ, Tanaka KF, Ushiba J, Okano H. Calcium Transient Dynamics of Neural Ensembles in the Primary Motor Cortex of Naturally Behaving Monkeys. Cell Reports. 24: 2191-2195.e4. PMID 30134178 DOI: 10.1016/J.Celrep.2018.07.057  0.393
2018 Ikoma Y, Kusumoto-Yoshida I, Yamanaka A, Ootsuka Y, Kuwaki T. Inactivation of Serotonergic Neurons in the Rostral Medullary Raphé Attenuates Stress-Induced Tachypnea and Tachycardia in Mice. Frontiers in Physiology. 9: 832. PMID 30050449 DOI: 10.3389/Fphys.2018.00832  0.398
2018 Moriya S, Yamashita A, Kawashima S, Nishi R, Yamanaka A, Kuwaki T. Acute aversive stimuli rapidly increase the activity of ventral tegmental area dopamine neurons in awake mice. Neuroscience. PMID 29958943 DOI: 10.1016/J.Neuroscience.2018.06.027  0.443
2018 Thannickal TC, John J, Shan L, Swaab DF, Wu MF, Ramanathan L, McGregor R, Chew KT, Cornford M, Yamanaka A, Inutsuka A, Fronczek R, Lammers GJ, Worley PF, Siegel JM. Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy. Science Translational Medicine. 10. PMID 29950444 DOI: 10.1126/Scitranslmed.Aao4953  0.43
2018 Black SW, Sun JD, Santiago P, Laihsu A, Kimura N, Yamanaka A, Bersot R, Humphries PS. Partial ablation of the orexin field induces a sub narcoleptic phenotype in a conditional mouse model of orexin neurodegeneration. Sleep. PMID 29860347 DOI: 10.1093/Sleep/Zsy116  0.391
2018 Miyazaki K, Miyazaki KW, Yamanaka A, Tokuda T, Tanaka KF, Doya K. Reward probability and timing uncertainty alter the effect of dorsal raphe serotonin neurons on patience. Nature Communications. 9: 2048. PMID 29858574 DOI: 10.1038/S41467-018-04496-Y  0.411
2018 Koizumi K, Inoue M, Chowdhury S, Bito H, Yamanaka A, Ishizuka T, Yawo H. Functional emergence of a column-like architecture in layer 5 of mouse somatosensory cortex in vivo. The Journal of Physiological Sciences : Jps. PMID 29761270 DOI: 10.1007/S12576-018-0618-4  0.756
2018 Ono D, Honma KI, Yanagawa Y, Yamanaka A, Honma S. Role of GABA in the regulation of the central circadian clock of the suprachiasmatic nucleus. The Journal of Physiological Sciences : Jps. PMID 29560549 DOI: 10.1007/S12576-018-0604-X  0.349
2018 Hashimoto M, Yamanaka A, Kato S, Tanifuji M, Kobayashi K, Yaginuma H. Anatomical Evidence for a Direct Projection from Purkinje Cells in the Mouse Cerebellar Vermis to Medial Parabrachial Nucleus. Frontiers in Neural Circuits. 12: 6. PMID 29467628 DOI: 10.3389/Fncir.2018.00006  0.347
2018 Futatsuki T, Yamashita A, Ikbar KN, Yamanaka A, Arita K, Kakihana Y, Kuwaki T. Involvement of orexin neurons in fasting- and central adenosine-induced hypothermia. Scientific Reports. 8: 2717. PMID 29426934 DOI: 10.1038/S41598-018-21252-W  0.441
2018 Suda Y, Kuzumaki N, Narita M, Hamada Y, Shibasaki M, Tanaka K, Tamura H, Kawamura T, Kondo T, Yamanaka A, Narita M. Effect of ghrelin on the motor deficit caused by the ablation of nigrostriatal dopaminergic cells or the inhibition of striatal dopamine receptors. Biochemical and Biophysical Research Communications. PMID 29378186 DOI: 10.1016/J.Bbrc.2018.01.145  0.371
2018 Watanabe M, Narita M, Hamada Y, Yamashita A, Tamura H, Ikegami D, Kondo T, Shinzato T, Shimizu T, Fukuchi Y, Muto A, Okano H, Yamanaka A, Tawfik V, Kuzumaki N, et al. [EXPRESS] Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer. Molecular Pain. 1744806918756406. PMID 29357732 DOI: 10.1177/1744806918756406  0.4
2017 Kikusui T, Kajita M, Otsuka N, Hattori T, Kumazawa K, Watarai A, Nagasawa M, Inutsuka A, Yamanaka A, Matsuo N, Covington HE, Mogi K. Sex differences in olfactory-induced neural activation of the amygdala. Behavioural Brain Research. PMID 29203334 DOI: 10.1016/J.Bbr.2017.11.034  0.327
2017 Nasanbuyan N, Yoshida M, Takayanagi Y, Inutsuka A, Nishimori K, Yamanaka A, Onaka T. Oxytocin-oxytocin receptor systems facilitate social defeat posture in male mice. Endocrinology. PMID 29186377 DOI: 10.1210/En.2017-00606  0.396
2017 Ono D, Yamanaka A. Hypothalamic regulation of the sleep/wake cycle. Neuroscience Research. PMID 28526553 DOI: 10.1016/J.Neures.2017.03.013  0.485
2017 Yamashita T, Yamanaka A. Lateral hypothalamic circuits for sleep-wake control. Current Opinion in Neurobiology. 44: 94-100. PMID 28427008 DOI: 10.1016/J.Conb.2017.03.020  0.659
2017 Dergacheva O, Yamanaka A, Schwartz AR, Polotsky VY, Mendelowitz D. Optogenetic identification of hypothalamic orexin neuron projections to paraventricular spinally projecting neurons. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00572.2016. PMID 28159808 DOI: 10.1152/Ajpheart.00572.2016  0.494
2017 Terao A, Ueno T, Okamatsu-Ogura Y, Kimura K, Tsunematsu T, Yamanaka A. 0104 Temporally Controlled Cell-Specific Ablation Of Melanin-Concentrating Hormone (Mch) Neurons Attenuate Non-Rem Sleep In Mice Sleep. 40. DOI: 10.1093/Sleepj/Zsx050.103  0.441
2017 Heiss J, Yamanaka A, Kilduff T. 0100 LATERAL HYPOTHALAMIC HYPOCRETIN AND NON-HYPOCRETIN NEURONS ACTIVATE PARALLEL AROUSAL PATHWAYS Sleep. 40: A37-A38. DOI: 10.1093/Sleepj/Zsx050.099  0.467
2016 Chowdhury S, Yamanaka A. Optogenetic activation of serotonergic terminals facilitates GABAergic inhibitory input to orexin/hypocretin neurons. Scientific Reports. 6: 36039. PMID 27824065 DOI: 10.1038/Srep36039  0.806
2016 Dergacheva O, Yamanaka A, Schwartz AR, Polotsky VY, Mendelowitz D. Direct projections from hypothalamic orexin neurons to brainstem cardiac vagal neurons. Neuroscience. PMID 27693474 DOI: 10.1016/J.Neuroscience.2016.09.038  0.489
2016 Dergacheva O, Yamanaka A, Schwartz AR, Polotsky VY, Mendelowitz D. Hypoxia and hypercapnia inhibit hypothalamic orexin neurons in rats. Journal of Neurophysiology. jn.00196.2016. PMID 27559138 DOI: 10.1152/Jn.00196.2016  0.38
2016 Inutsuka A, Yamashita A, Chowdhury S, Nakai J, Ohkura M, Taguchi T, Yamanaka A. The integrative role of orexin/hypocretin neurons in nociceptive perception and analgesic regulation. Scientific Reports. 6: 29480. PMID 27385517 DOI: 10.1038/Srep29480  0.812
2016 Miyamoto D, Hirai D, Fung CC, Inutsuka A, Odagawa M, Suzuki T, Boehringer R, Adaikkan C, Matsubara C, Matsuki N, Fukai T, McHugh TJ, Yamanaka A, Murayama M. Top-down cortical input during NREM sleep consolidates perceptual memory. Science (New York, N.Y.). PMID 27229145 DOI: 10.1126/Science.Aaf0902  0.757
2015 Fuller PM, Yamanaka A, Lazarus M. How genetically engineered systems are helping to define, and in some cases redefine, the neurobiological basis of sleep and wake. Temperature (Austin, Tex.). 2: 406-17. PMID 27227054 DOI: 10.1080/23328940.2015.1075095  0.311
2015 Black SW, Yamanaka A, Kilduff TS. CHALLENGES IN THE DEVELOPMENT OF THERAPEUTICS FOR NARCOLEPSY. Progress in Neurobiology. PMID 26721620 DOI: 10.1016/J.Pneurobio.2015.12.002  0.351
2015 Hososhima S, Yuasa H, Ishizuka T, Hoque MR, Yamashita T, Yamanaka A, Sugano E, Tomita H, Yawo H. Near-infrared (NIR) up-conversion optogenetics. Scientific Reports. 5: 16533. PMID 26552717 DOI: 10.1038/Srep16533  0.588
2015 Branch AF, Navidi W, Tabuchi S, Terao A, Yamanaka A, Scammell TE, Behn CD. Progressive Loss of the Orexin Neurons Reveals Dual Effects on Wakefulness. Sleep. PMID 26446125 DOI: 10.5665/sleep.5446  0.404
2015 Yamanaka A. Controlling sleep/wakefulness using optogenetics Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 35: 97-102. PMID 26434098  0.458
2015 Ishii K, Kubo K, Endo T, Yoshida K, Benner S, Ito Y, Aizawa H, Aramaki M, Yamanaka A, Tanaka K, Takata N, Tanaka KF, Mimura M, Tohyama C, Kakeyama M, et al. Neuronal Heterotopias Affect the Activities of Distant Brain Areas and Lead to Behavioral Deficits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12432-45. PMID 26354912 DOI: 10.1523/Jneurosci.3648-14.2015  0.409
2015 Shibasaki K, Sugio S, Takao K, Yamanaka A, Miyakawa T, Tominaga M, Ishizaki Y. TRPV4 activation at the physiological temperature is a critical determinant of neuronal excitability and behavior. Pflugers Archiv : European Journal of Physiology. PMID 26250433 DOI: 10.1007/S00424-015-1726-0  0.442
2015 Manita S, Suzuki T, Homma C, Matsumoto T, Odagawa M, Yamada K, Ota K, Matsubara C, Inutsuka A, Sato M, Ohkura M, Yamanaka A, Yanagawa Y, Nakai J, Hayashi Y, et al. A Top-Down Cortical Circuit for Accurate Sensory Perception. Neuron. 86: 1304-16. PMID 26004915 DOI: 10.1016/J.Neuron.2015.05.006  0.497
2015 Kato HE, Kamiya M, Sugo S, Ito J, Taniguchi R, Orito A, Hirata K, Inutsuka A, Yamanaka A, Maturana AD, Ishitani R, Sudo Y, Hayashi S, Nureki O. Atomistic design of microbial opsin-based blue-shifted optogenetics tools. Nature Communications. 6: 7177. PMID 25975962 DOI: 10.1038/Ncomms8177  0.305
2015 Yamanaka A, Tsunematsu T. Elucidation of neuronal circuitry involved in the regulation of sleep/wakefulness using optogenetics Orexin and Sleep: Molecular, Functional and Clinical Aspects. 81-92. DOI: 10.1007/978-3-319-23078-8_6  0.359
2014 Miyazaki KW, Miyazaki K, Tanaka KF, Yamanaka A, Takahashi A, Tabuchi S, Doya K. Optogenetic activation of dorsal raphe serotonin neurons enhances patience for future rewards. Current Biology : Cb. 24: 2033-40. PMID 25155504 DOI: 10.1016/J.Cub.2014.07.041  0.45
2014 Inutsuka A, Inui A, Tabuchi S, Tsunematsu T, Lazarus M, Yamanaka A. Concurrent and robust regulation of feeding behaviors and metabolism by orexin neurons. Neuropharmacology. 85: 451-60. PMID 24951857 DOI: 10.1016/J.Neuropharm.2014.06.015  0.491
2014 Ohmura Y, Tanaka KF, Tsunematsu T, Yamanaka A, Yoshioka M. Optogenetic activation of serotonergic neurons enhances anxiety-like behaviour in mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 1777-83. PMID 24834486 DOI: 10.1017/S1461145714000637  0.392
2014 Tsunematsu T, Ueno T, Tabuchi S, Inutsuka A, Tanaka KF, Hasuwa H, Kilduff TS, Terao A, Yamanaka A. Optogenetic manipulation of activity and temporally controlled cell-specific ablation reveal a role for MCH neurons in sleep/wake regulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6896-909. PMID 24828644 DOI: 10.1523/Jneurosci.5344-13.2014  0.477
2014 Tabuchi S, Tsunematsu T, Black SW, Tominaga M, Maruyama M, Takagi K, Minokoshi Y, Sakurai T, Kilduff TS, Yamanaka A. Conditional ablation of orexin/hypocretin neurons: a new mouse model for the study of narcolepsy and orexin system function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6495-509. PMID 24806676 DOI: 10.1523/Jneurosci.0073-14.2014  0.498
2014 Black SW, Morairty SR, Chen TM, Leung AK, Wisor JP, Yamanaka A, Kilduff TS. GABAB agonism promotes sleep and reduces cataplexy in murine narcolepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6485-94. PMID 24806675 DOI: 10.1523/Jneurosci.0080-14.2014  0.303
2013 Tabuchi S, Tsunematsu T, Kilduff TS, Sugio S, Xu M, Tanaka KF, Takahashi S, Tominaga M, Yamanaka A. Influence of inhibitory serotonergic inputs to orexin/hypocretin neurons on the diurnal rhythm of sleep and wakefulness. Sleep. 36: 1391-404. PMID 23997373 DOI: 10.5665/Sleep.2972  0.509
2013 Tsujino N, Tsunematsu T, Uchigashima M, Konno K, Yamanaka A, Kobayashi K, Watanabe M, Koyama Y, Sakurai T. Chronic alterations in monoaminergic cells in the locus coeruleus in orexin neuron-ablated narcoleptic mice. Plos One. 8: e70012. PMID 23922890 DOI: 10.1371/Journal.Pone.0070012  0.521
2013 Tsunematsu T, Tabuchi S, Tanaka KF, Boyden ES, Tominaga M, Yamanaka A. Long-lasting silencing of orexin/hypocretin neurons using archaerhodopsin induces slow-wave sleep in mice. Behavioural Brain Research. 255: 64-74. PMID 23707248 DOI: 10.1016/J.Bbr.2013.05.021  0.529
2013 Inutsuka A, Yamanaka A. The regulation of sleep and wakefulness by the hypothalamic neuropeptide orexin/hypocretin. Nagoya Journal of Medical Science. 75: 29-36. PMID 23544265 DOI: 10.18999/Nagjms.75.1-2.29  0.498
2013 Inutsuka A, Yamanaka A. The physiological role of orexin/hypocretin neurons in the regulation of sleep/wakefulness and neuroendocrine functions. Frontiers in Endocrinology. 4: 18. PMID 23508038 DOI: 10.3389/Fendo.2013.00018  0.509
2013 Koizumi A, Tanaka KF, Yamanaka A. The manipulation of neural and cellular activities by ectopic expression of melanopsin. Neuroscience Research. 75: 3-5. PMID 22982474 DOI: 10.1016/J.Neures.2012.07.010  0.357
2013 Tsunematsu T, Tanaka KF, Yamanaka A, Koizumi A. Ectopic expression of melanopsin in orexin/hypocretin neurons enables control of wakefulness of mice in vivo by blue light. Neuroscience Research. 75: 23-8. PMID 22868039 DOI: 10.1016/J.Neures.2012.07.005  0.494
2013 Imayoshi I, Tabuchi S, Hirano K, Sakamoto M, Kitano S, Miyachi H, Yamanaka A, Kageyama R. Light-induced silencing of neural activity in Rosa26 knock-in mice conditionally expressing the microbial halorhodopsin eNpHR2.0. Neuroscience Research. 75: 53-8. PMID 22465523 DOI: 10.1016/J.Neures.2012.03.008  0.361
2013 Yamanaka A. Control of Sleep/Wakefulness by Using Optogenetics for Study of Sleep Disease The Review of Laser Engineering. 41: 92. DOI: 10.2184/Lsj.41.2_92  0.308
2012 Yamanaka A. [Optogenetical approach to control the activity of specific types of neurons in vivo]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 140: 280-4. PMID 23229635 DOI: DN/JST.JSTAGE/fpj/140.280  0.325
2012 Tanaka KF, Matsui K, Sasaki T, Sano H, Sugio S, Fan K, Hen R, Nakai J, Yanagawa Y, Hasuwa H, Okabe M, Deisseroth K, Ikenaka K, Yamanaka A. Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Reports. 2: 397-406. PMID 22854021 DOI: 10.1016/J.Celrep.2012.06.011  0.349
2012 Tsunematsu T, Yamanaka A. The role of orexin/hypocretin in the central nervous system and peripheral tissues. Vitamins and Hormones. 89: 19-33. PMID 22640606 DOI: 10.1016/B978-0-12-394623-2.00002-0  0.41
2011 Tsunematsu T, Kilduff TS, Boyden ES, Takahashi S, Tominaga M, Yamanaka A. Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10529-39. PMID 21775598 DOI: 10.1523/Jneurosci.0784-11.2011  0.545
2011 Hirashima N, Tsunematsu T, Ichiki K, Tanaka H, Kilduff TS, Yamanaka A. Neuropeptide B induces slow wave sleep in mice. Sleep. 34: 31-7. PMID 21203369 DOI: 10.1093/Sleep/34.1.31  0.371
2011 Tsujino N, Tsunematsu T, Yamanaka A, Koyama Y, Sakurai T. Alterations in noradrenergic neurons in orexin neuron-deficient mice Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.735  0.489
2011 Tabuchi S, Tsunematsu T, Sugio S, Tanaka K, Tominaga M, Yamanaka A. Reversible gene expression control of serotonin receptor 1A in orexin neurons reveals physiological significance of serotonergic inhibitory inputs to orexin neurons Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.223  0.453
2011 Tanaka K, Yamanaka A, Koizumi A. Manipulation of neuronal activity by ectopic expression of melanopsin Neuroscience Research. 71: e25. DOI: 10.1016/J.Neures.2011.07.104  0.47
2010 Mihara H, Boudaka A, Shibasaki K, Yamanaka A, Sugiyama T, Tominaga M. Involvement of TRPV2 activation in intestinal movement through nitric oxide production in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16536-44. PMID 21147993 DOI: 10.1523/Jneurosci.4426-10.2010  0.382
2010 Yamanaka A, Tabuchi S, Tsunematsu T, Fukazawa Y, Tominaga M. Orexin directly excites orexin neurons through orexin 2 receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 12642-52. PMID 20861370 DOI: 10.1523/Jneurosci.2120-10.2010  0.526
2010 Yamanaka A, Tsunematsu T. New approaches for the study of orexin function. Journal of Neuroendocrinology. 22: 818-24. PMID 20456607 DOI: 10.1111/J.1365-2826.2010.02015.X  0.535
2010 Tabuchi S, Tsunematsu T, Tominaga M, Fukazawa Y, Yamanaka A. Orexin 2 receptor positively regulates the activity of orexin neurons Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.110  0.435
2009 Yamanaka A, Tsunematsu T, Tominaga M. The transcriptome analysis of orexin neurons Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.1291  0.473
2009 Tsujino N, Tsunematsu T, Yamanaka A, Koyama Y, Sakurai T. Alterations in monoaminergic neurons in orexin neuron-ablated mice Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.1289  0.492
2008 Xie X, Wisor JP, Hara J, Crowder TL, LeWinter R, Khroyan TV, Yamanaka A, Diano S, Horvath TL, Sakurai T, Toll L, Kilduff TS. Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. The Journal of Clinical Investigation. 118: 2471-81. PMID 18551194 DOI: 10.1172/Jci35115  0.433
2008 Tsunematsu T, Fu LY, Yamanaka A, Ichiki K, Tanoue A, Sakurai T, van den Pol AN. Vasopressin increases locomotion through a V1a receptor in orexin/hypocretin neurons: implications for water homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 228-38. PMID 18171940 DOI: 10.1523/Jneurosci.3490-07.2008  0.432
2006 Xie X, Crowder TL, Yamanaka A, Morairty SR, Lewinter RD, Sakurai T, Kilduff TS. GABA(B) receptor-mediated modulation of hypocretin/orexin neurones in mouse hypothalamus. The Journal of Physiology. 574: 399-414. PMID 16627567 DOI: 10.1113/Jphysiol.2006.108266  0.304
2006 Yamanaka A, Muraki Y, Ichiki K, Tsujino N, Kilduff TS, Goto K, Sakurai T. Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner. Journal of Neurophysiology. 96: 284-98. PMID 16611835 DOI: 10.1152/Jn.01361.2005  0.409
2006 Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M. Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor. Endocrinology. 147: 2306-14. PMID 16484324 DOI: 10.1210/En.2005-1357  0.393
2005 Tsujino N, Yamanaka A, Ichiki K, Muraki Y, Kilduff TS, Yagami K, Takahashi S, Goto K, Sakurai T. Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7459-69. PMID 16093397 DOI: 10.1523/Jneurosci.1193-05.2005  0.437
2005 Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M. Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice. Neuron. 46: 297-308. PMID 15848807 DOI: 10.1016/J.Neuron.2005.03.010  0.53
2005 Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M. Erratum: Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice (Neuron (April 21, 2005) 46 (297-308) PII: S0896-6273(05)00205-9 and DOI: 10.1016/j.neuron.2005.03.010) Neuron. 46. DOI: 10.1016/J.Neuron.2005.04.029  0.487
2004 Winsky-Sommerer R, Yamanaka A, Diano S, Borok E, Roberts AJ, Sakurai T, Kilduff TS, Horvath TL, de Lecea L. Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11439-48. PMID 15601950 DOI: 10.1523/Jneurosci.3459-04.2004  0.419
2004 Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T. Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7159-66. PMID 15306649 DOI: 10.1523/Jneurosci.1027-04.2004  0.456
2004 Muroya S, Funahashi H, Yamanaka A, Kohno D, Uramura K, Nambu T, Shibahara M, Kuramochi M, Takigawa M, Yanagisawa M, Sakurai T, Shioda S, Yada T. Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose-responsive neurons to regulate Ca 2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus. The European Journal of Neuroscience. 19: 1524-34. PMID 15066149 DOI: 10.1111/J.1460-9568.2004.03255.X  0.42
2004 Yamanaka A, Muraki Y, Tsujino N, Goto K, Sakurai T. Regulation of orexin neurons by the monoaminergic and cholinergic systems Sleep and Biological Rhythms. 2. DOI: 10.1111/J.1479-8425.2004.00119.X  0.44
2004 Yamanaka A, Beuckmann CT, Willie JT, Hara J, Tsujino N, Goto K, Yanagisawa M, Sakurai T. Role of hypothalamic orexin neurons in the regulation of arousal according to energy balance Sleep and Biological Rhythms. 2: S57. DOI: 10.1111/J.1479-8425.2004.00116.X  0.427
2003 Zhu Y, Miwa Y, Yamanaka A, Yada T, Shibahara M, Abe Y, Sakurai T, Goto K. Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins. Journal of Pharmacological Sciences. 92: 259-66. PMID 12890892 DOI: 10.1254/Jphs.92.259  0.353
2003 Yamanaka A, Beuckmann CT, Willie JT, Hara J, Tsujino N, Mieda M, Tominaga M, Yagami Ki, Sugiyama F, Goto K, Yanagisawa M, Sakurai T. Hypothalamic orexin neurons regulate arousal according to energy balance in mice. Neuron. 38: 701-13. PMID 12797956 DOI: 10.1016/S0896-6273(03)00331-3  0.452
2003 Yamanaka A, Muraki Y, Tsujino N, Goto K, Sakurai T. Regulation of orexin neurons by the monoaminergic and cholinergic systems. Biochemical and Biophysical Research Communications. 303: 120-9. PMID 12646175 DOI: 10.1016/S0006-291X(03)00299-7  0.531
2002 Yamanaka A, Tsujino N, Funahashi H, Honda K, Guan JL, Wang QP, Tominaga M, Goto K, Shioda S, Sakurai T. Orexins activate histaminergic neurons via the orexin 2 receptor. Biochemical and Biophysical Research Communications. 290: 1237-45. PMID 11811995 DOI: 10.1006/Bbrc.2001.6318  0.486
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