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James T. Murray, MA, MPP - Publications

Affiliations: 
2013-2015 Philosophy Queen's University, Kingston, ON, Canada 
Area:
Self-Defense ethics, desert considerations
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Maragno AL, Mistry P, Kotschy A, Szlavik Z, Murray J, Davidson J, Toumelin-Braizat GL, Chanrion M, Bruno A, Claperon A, Maacke H, Morris E, Wang Y, Derreal A, Csekei M, et al. Abstract 4482: S64315 (MIK665) is a potent and selective Mcl1 inhibitor with strong antitumor activity across a diverse range of hematologic tumor models Cancer Research. 79: 4482-4482. DOI: 10.1158/1538-7445.Am2019-4482  0.307
2018 Murray JT, Tee AR. Mechanistic Target of Rapamycin (mTOR) in the Cancer Setting. Cancers. 10. PMID 29848950 DOI: 10.3390/Cancers10060168  0.344
2018 Rad E, Murray JT, Tee AR. Oncogenic Signalling through Mechanistic Target of Rapamycin (mTOR): A Driver of Metabolic Transformation and Cancer Progression. Cancers. 10. PMID 29301334 DOI: 10.3390/Cancers10010005  0.326
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Murray JT, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.312
2015 Diez-Cecilia E, Carson R, Kelly B, van Schaeybroeck S, Murray JT, Rozas I. Probing a 3,4'-bis-guanidinium diaryl derivative as an allosteric inhibitor of the Ras pathway. Bioorganic & Medicinal Chemistry Letters. 25: 4287-92. PMID 26318998 DOI: 10.1016/J.Bmcl.2015.07.082  0.341
2014 Moore JD, Staniszewska A, Shaw T, D'Alessandro J, Davis B, Surgenor A, Baker L, Matassova N, Murray J, Macias A, Brough P, Wood M, Mahon PC. VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells. Oncotarget. 5: 12862-76. PMID 25404640 DOI: 10.18632/Oncotarget.2656  0.347
2014 Huang YH, Al-Aidaroos AQ, Yuen HF, Zhang SD, Shen HM, Rozycka E, McCrudden CM, Tergaonkar V, Gupta A, Lin YB, Thiery JP, Murray JT, Zeng Q. A role of autophagy in PTP4A3-driven cancer progression. Autophagy. 10: 1787-800. PMID 25136802 DOI: 10.4161/Auto.29989  0.356
2014 Dunlop EA, Seifan S, Claessens T, Behrends C, Kamps MA, Rozycka E, Kemp AJ, Nookala RK, Blenis J, Coull BJ, Murray JT, van Steensel MA, Wilkinson S, Tee AR. FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation. Autophagy. 10: 1749-60. PMID 25126726 DOI: 10.4161/Auto.29640  0.351
2014 D'Costa ZC, Higgins C, Ong CW, Irwin GW, Boyle D, McArt DG, McCloskey K, Buckley NE, Crawford NT, Thiagarajan L, Murray JT, Kennedy RD, Mulligan KA, Harkin DP, Waugh DJ, et al. TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities. Oncotarget. 5: 1609-20. PMID 24742492 DOI: 10.18632/Oncotarget.1707  0.316
2014 Matchett KB, McFarlane S, Hamilton SE, Eltuhamy YS, Davidson MA, Murray JT, Faheem AM, El-Tanani M. Ran GTPase in nuclear envelope formation and cancer metastasis. Advances in Experimental Medicine and Biology. 773: 323-51. PMID 24563355 DOI: 10.1007/978-1-4899-8032-8_15  0.326
2013 Sahin P, Mccaig C, Jeevahan J, Murray JT, Hainsworth AH. The cell survival kinase SGK1 and its targets FOXO3a and NDRG1 in aged human brain Neuropathology and Applied Neurobiology. 39: 623-633. PMID 23363009 DOI: 10.1111/Nan.12023  0.308
2013 Pike LR, Singleton DC, Buffa F, Abramczyk O, Phadwal K, Li JL, Simon AK, Murray JT, Harris AL. Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival. The Biochemical Journal. 449: 389-400. PMID 23078367 DOI: 10.1042/Bj20120972  0.353
2013 Moore J, Staniszewska A, Shaw T, D'Alessandro J, Davis B, Surgenor A, Baker L, Massanova N, Murray J, Macias A, Brough P, Wood M, Mahon PC. Abstract B155: VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and demonstrates context-dependent cytotoxicity to cancer cells. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B155  0.381
2012 Yuen HF, Abramczykd O, Montgomery G, Chan KK, Huang YH, Sasazuki T, Shirasawa S, Gopesh S, Chan KW, Fennell D, Janne P, El-Tanani M, Murray JT. Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells Bioscience Reports. 32: 413-422. PMID 22668349 DOI: 10.1042/Bsr20120050  0.353
2012 Yuen HF, Chan KK, Grills C, Murray JT, Platt-Higgins A, Eldin OS, O'Byrne K, Janne P, Fennell DA, Johnston PG, Rudland PS, El-Tanani M. Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways Clinical Cancer Research. 18: 380-391. PMID 22090358 DOI: 10.1158/1078-0432.Ccr-11-2035  0.36
2011 McCaig C, Potter L, Abramczyk O, Murray JT. Phosphorylation of NDRG1 is temporally and spatially controlled during the cell cycle Biochemical and Biophysical Research Communications. 411: 227-234. PMID 21708134 DOI: 10.1016/J.Bbrc.2011.06.092  0.366
2010 McCoy F, Hurwitz J, McTavish N, Paul I, Barnes C, O'Hagan B, Odrzywol K, Murray J, Longley D, McKerr G, Fennell DA. Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK Cell Death and Disease. 1. PMID 21368880 DOI: 10.1038/Cddis.2010.86  0.343
2009 Marusich MF, Murray J, Xie J, Capaldi RA. Novel antibody-based strategies for the rapid diagnosis of mitochondrial disease and dysfunction. The International Journal of Biochemistry & Cell Biology. 41: 2081-8. PMID 19460456 DOI: 10.1016/J.Biocel.2009.05.009  0.323
2009 Inglis SK, Gallacher M, Brown SG, McTavish N, Getty J, Husband EM, Murray JT, Wilson SM. SGK1 activity in Na+ absorbing airway epithelial cells monitored by assaying NDRG1-Thr346/356/366 phosphorylation. Pflã¼Gers Archiv : European Journal of Physiology. 457: 1287-301. PMID 18787837 DOI: 10.1007/S00424-008-0587-1  0.339
2009 McCoy FGP, Paul I, Hurwitz JL, O'Hagan B, Odrzywol K, Murray JT, McKerr G, Fennell DA. Abstract B30: Phosphorylation of c‐jun N terminal kinase (JNK) regulates induction of mitochondrial apoptosis by pro‐suvival BCL‐2 antagoinist obatoclax Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B30  0.393
2008 Murray J, Capaldi RA. Screening for the metabolic basis of neurodegeneration: developing a focused proteomic approach. Annals of the New York Academy of Sciences. 1147: 348-57. PMID 19076456 DOI: 10.1196/Annals.1427.025  0.306
2007 MacKenzie MG, Hamilton DL, Murray JT, Baar K. mVps34 is activated by an acute bout of resistance exercise Biochemical Society Transactions. 35: 1314-1316. PMID 17956340 DOI: 10.1042/Bst0351314  0.309
2005 Murray JT, Backer JM. Analysis of hVps34/hVps15 interactions with Rab5 in Vivo and in Vitro Methods in Enzymology. 403: 789-799. PMID 16473639 DOI: 10.1016/S0076-6879(05)03068-5  0.326
2005 Byfield MP, Murray JT, Backer JM. hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase Journal of Biological Chemistry. 280: 33076-33082. PMID 16049009 DOI: 10.1074/Jbc.M507201200  0.361
2005 Rixon HWM, Brown G, Murray JT, Sugrue RJ. The respiratory syncytial virus small hydrophobic protein is phosphorylated via a mitogen-activated protein kinase p38-dependent tyrosine kinase activity during virus infection Journal of General Virology. 86: 375-384. PMID 15659757 DOI: 10.1099/Vir.0.80563-0  0.353
2004 Murray JT, Campbell DG, Morrice N, Auld GC, Shpiro N, Marquez R, Peggie M, Bain J, Bloomberg GB, Grahammer F, Lang F, Wulff P, Kuhl D, Cohen P. Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3. The Biochemical Journal. 384: 477-88. PMID 15461589 DOI: 10.1042/Bj20041057  0.342
2004 Murray JT, Campbell DG, Peggie M, Alfonso M, Cohen P. Identification of filamin C as a new physiological substrate of PKβα using KESTREL Biochemical Journal. 384: 489-494. PMID 15461588 DOI: 10.1042/Bj20041058  0.35
2004 Murray J, Marusich MF, Capaldi RA, Aggeler R. Focused proteomics: monoclonal antibody-based isolation of the oxidative phosphorylation machinery and detection of phosphoproteins using a fluorescent phosphoprotein gel stain. Electrophoresis. 25: 2520-5. PMID 15300771 DOI: 10.1002/Elps.200406006  0.3
2000 Murray JT, Craggs G, Wilson L, Kellie S. Mechanism of phosphatidylinositol 3-kinase-dependent increases in BAC1.2F5 macrophage-like cell density in response to M-CSF: Phosphatidylinositol 3-kinase inhibitors increase the rate of apoptosis rather than inhibit DNA synthesis Inflammation Research. 49: 610-618. PMID 11131301 DOI: 10.1007/S000110050638  0.356
2000 Hill K, Welti S, Yu J, Murray JT, Yip SC, Condeelis JS, Segall JE, Backer JM. Specific requirement for the p85-p110alpha phosphatidylinositol 3-kinase during epidermal growth factor-stimulated actin nucleation in breast cancer cells. The Journal of Biological Chemistry. 275: 3741-4. PMID 10660520 DOI: 10.1074/Jbc.275.6.3741  0.334
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