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Trey Hedden - Publications

Affiliations: 
Neurology Icahn School of Medicine at Mount Sinai, New York, NY, United States 
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45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lee H, Fu JF, Gaudet K, Bryant AG, Price JC, Bennett RE, Johnson KA, Hyman BT, Hedden T, Salat DH, Yen YF, Huang SY. Aberrant vascular architecture in the hippocampus correlates with tau burden in mild cognitive impairment and Alzheimer's disease. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X231216144. PMID 38000018 DOI: 10.1177/0271678X231216144  0.359
2022 Eissman JM, Dumitrescu L, Mahoney ER, Smith AN, Mukherjee S, Lee ML, Scollard P, Choi SE, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski CC, ... ... Hedden T, et al. Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease. Brain : a Journal of Neurology. PMID 35552371 DOI: 10.1093/brain/awac177  0.313
2022 Rabin JS, Pruzin J, Scott M, Yang HS, Hampton O, Hsieh S, Schultz AP, Buckley RF, Hedden T, Rentz D, Johnson KA, Sperling RA, Chhatwal JP. Association of β-Amyloid and Vascular Risk on Longitudinal Patterns of Brain Atrophy. Neurology. PMID 35473760 DOI: 10.1212/WNL.0000000000200551  0.331
2020 Rabin JS, Neal TE, Nierle HE, Sikkes SAM, Buckley RF, Amariglio RE, Papp KV, Rentz DM, Schultz AP, Johnson KA, Sperling RA, Hedden T. Multiple markers contribute to risk of progression from normal to mild cognitive impairment. Neuroimage. Clinical. 28: 102400. PMID 32919366 DOI: 10.1016/J.Nicl.2020.102400  0.409
2020 Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski C, Hernandez Saucedo H, Widaman KF, Buckley R, Properzi M, ... ... Hedden T, et al. Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Brain : a Journal of Neurology. 143: 2561-2575. PMID 32844198 DOI: 10.1093/Brain/Awaa209  0.453
2020 Rabin JS, Shirzadi Z, Swardfager W, MacIntosh BJ, Schultz A, Yang HS, Buckley RF, Gatchel JR, Kirn D, Pruzin JJ, Hedden T, Lipsman N, Rentz DM, Black SE, Johnson KA, et al. Amyloid-beta burden predicts prospective decline in body mass index in clinically normal adults. Neurobiology of Aging. PMID 32249013 DOI: 10.1016/J.Neurobiolaging.2020.03.002  0.377
2019 Vannini P, Uquillas FD, Jacobs HIL, Sepulcre J, Gatchel J, Amariglio RE, Hanseeuw B, Papp KV, Hedden T, Rentz DM, Pascual-Leone A, Johnson KA, Sperling RA. Decreased meta-memory is associated with early tauopathy in cognitively unimpaired older adults. Neuroimage. Clinical. 24: 102097. PMID 31795044 DOI: 10.1016/J.Nicl.2019.102097  0.374
2019 Munoz E, Filshtein T, Bettcher BM, McLaren D, Hedden T, Tommet D, Mungas D, Therneau T. Cognitive function and neuropathological outcomes: a forward-looking approach. Journal of Neurology. PMID 31435771 DOI: 10.1007/S00415-019-09516-5  0.46
2019 Rabin JS, Klein H, Kirn DR, Schultz AP, Yang HS, Hampton O, Jiang S, Buckley RF, Viswanathan A, Hedden T, Pruzin J, Yau WW, Guzmán-Vélez E, Quiroz YT, Properzi M, et al. Associations of Physical Activity and β-Amyloid With Longitudinal Cognition and Neurodegeneration in Clinically Normal Older Adults. Jama Neurology. PMID 31312836 DOI: 10.1001/Jamaneurol.2019.1879  0.436
2019 Rabin JS, Perea RD, Buckley RF, Johnson KA, Sperling RA, Hedden T. Synergism between fornix microstructure and beta amyloid accelerates memory decline in clinically normal older adults. Neurobiology of Aging. 81: 38-46. PMID 31207468 DOI: 10.1016/j.neurobiolaging.2019.05.005  0.417
2019 Hanseeuw BJ, Betensky RA, Jacobs HIL, Schultz AP, Sepulcre J, Becker JA, Cosio DMO, Farrell M, Quiroz YT, Mormino EC, Buckley RF, Papp KV, Amariglio RA, Dewachter I, Ivanoiu A, ... ... Hedden T, et al. Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study. Jama Neurology. PMID 31157827 DOI: 10.1001/Jamaneurol.2019.1424  0.377
2019 Yang HS, Chhatwal JP, Xu J, White CC, Hanseeuw B, Rabin JS, Papp KV, Buckley RF, Schultz AP, Properzi MJ, Gatchel JR, Amariglio RE, Donovan NJ, Mormino EC, Hedden T, et al. An UNC5C Allele Predicts Cognitive Decline and Hippocampal Atrophy in Clinically Normal Older Adults. Journal of Alzheimer's Disease : Jad. PMID 30883345 DOI: 10.3233/Jad-180788  0.436
2018 Rabin JS, Yang HS, Schultz AP, Hanseeuw BJ, Hedden T, Viswanathan A, Gatchel JR, Marshall GA, Kilpatrick E, Klein H, Rao V, Buckley RF, Yau WW, Kirn DR, Rentz DM, et al. Vascular risk and β-amyloid are synergistically associated with cortical tau. Annals of Neurology. PMID 30565287 DOI: 10.1002/Ana.25399  0.33
2018 Sperling RA, Mormino EC, Schultz AP, Betensky RA, Papp KV, Amariglio RE, Hanseeuw BJ, Buckley R, Chhatwal J, Hedden T, Marshall GA, Quiroz YT, Donovan NJ, Jackson J, Gatchel JR, et al. The impact of Aβ and tau on prospective cognitive decline in older individuals. Annals of Neurology. PMID 30549303 DOI: 10.1002/Ana.25395  0.458
2018 Huijbers W, Schultz AP, Papp KV, LaPoint MR, Hanseeuw B, Chhatwal JP, Hedden T, Johnson KA, Sperling RA. Tau accumulation in clinically normal older adults is associated with hippocampal hyperactivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30482786 DOI: 10.1523/Jneurosci.1397-18.2018  0.352
2018 Rieckmann A, Johnson KA, Sperling RA, Buckner RL, Hedden T. Dedifferentiation of caudate functional connectivity and striatal dopamine transporter density predict memory change in normal aging. Proceedings of the National Academy of Sciences of the United States of America. PMID 30224467 DOI: 10.1073/pnas.1804641115  0.304
2018 Buckley RF, Mormino EC, Amariglio RE, Properzi MJ, Rabin JS, Lim YY, Papp KV, Jacobs HIL, Burnham S, Hanseeuw BJ, Doré V, Dobson A, Masters CL, Waller M, Rowe CC, ... ... Hedden T, et al. Sex, amyloid, and APOE ε4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29803541 DOI: 10.1016/J.Jalz.2018.04.010  0.426
2018 Rabin JS, Schultz AP, Hedden T, Viswanathan A, Marshall GA, Kilpatrick E, Klein H, Buckley RF, Yang HS, Properzi M, Rao V, Kirn DR, Papp KV, Rentz DM, Johnson KA, et al. Interactive Associations of Vascular Risk and β-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study. Jama Neurology. PMID 29799986 DOI: 10.1001/Jamaneurol.2018.1123  0.476
2018 Orlovsky I, Huijbers W, Hanseeuw BJ, Mormino EC, Hedden T, Buckley RF, LaPoint M, Rabin JS, Rentz DM, Johnson KA, Sperling RA, Papp KV. The relationship between recall of recently versus remotely encoded famous faces and amyloidosis in clinically normal older adults. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 121-129. PMID 29780861 DOI: 10.1016/J.Dadm.2017.11.003  0.345
2018 Chhatwal JP, Schultz AP, Johnson KA, Hedden T, Jaimes S, Benzinger TLS, Jack C, Ances BM, Ringman JM, Marcus DS, Ghetti B, Farlow MR, Danek A, Levin J, Yakushev I, et al. Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing. Brain : a Journal of Neurology. PMID 29522171 DOI: 10.1093/Brain/Awy053  0.339
2018 Rabin JS, Perea RD, Buckley RF, Neal TE, Buckner RL, Johnson KA, Sperling RA, Hedden T. Global White Matter Diffusion Characteristics Predict Longitudinal Cognitive Change Independently of Amyloid Status in Clinically Normal Older Adults. Cerebral Cortex (New York, N.Y. : 1991). PMID 29425267 DOI: 10.1093/cercor/bhy031  0.395
2018 Jacobs HIL, Hedden T, Schultz AP, Sepulcre J, Perea RD, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. Structural tract alterations predict downstream tau accumulation in amyloid-positive older individuals. Nature Neuroscience. PMID 29403032 DOI: 10.1038/s41593-018-0070-z  0.364
2017 Buckley RF, Schultz AP, Hedden T, Papp KV, Hanseeuw BJ, Marshall G, Sepulcre J, Smith EE, Rentz DM, Johnson KA, Sperling RA, Chhatwal JP. Functional network integrity presages cognitive decline in preclinical Alzheimer disease. Neurology. PMID 28592457 DOI: 10.1212/Wnl.0000000000004059  0.417
2016 Mormino EC, Papp KV, Rentz DM, Schultz AP, LaPoint M, Amariglio R, Hanseeuw B, Marshall GA, Hedden T, Johnson KA, Sperling RA. Heterogeneity in Suspected Non-Alzheimer Disease Pathophysiology Among Clinically Normal Older Individuals. Jama Neurology. PMID 27548655 DOI: 10.1001/jamaneurol.2016.2237  0.337
2016 Fotiadis P, van Rooden S, van der Grond J, Schultz A, Martinez-Ramirez S, Auriel E, Reijmer Y, van Opstal AM, Ayres A, Schwab KM, Alzheimer's Disease Neuroimaging Initiative Adni, Hedden T, Rosand J, Viswanathan A, Wermer M, et al. Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study. The Lancet. Neurology. PMID 27180034 DOI: 10.1016/S1474-4422(16)30030-8  0.327
2016 Rieckmann A, Van Dijk KR, Sperling RA, Johnson KA, Buckner RL, Hedden T. Accelerated decline in white matter integrity in clinically normal individuals at risk for Alzheimer's disease. Neurobiology of Aging. 42: 177-88. PMID 27143434 DOI: 10.1016/j.neurobiolaging.2016.03.016  0.333
2015 Gidicsin CM, Maye JE, Locascio JJ, Pepin LC, Philiossaint M, Becker JA, Younger AP, Dekhtyar M, Schultz AP, Amariglio RE, Marshall GA, Rentz DM, Hedden T, Sperling RA, Johnson KA. Cognitive activity relates to cognitive performance but not to Alzheimer disease biomarkers. Neurology. 85: 48-55. PMID 26062627 DOI: 10.1212/Wnl.0000000000001704  0.439
2015 Papp KV, Amariglio RE, Mormino EC, Hedden T, Dekhytar M, Johnson KA, Sperling RA, Rentz DM. Free and cued memory in relation to biomarker-defined abnormalities in clinically normal older adults and those at risk for Alzheimer's disease. Neuropsychologia. 73: 169-75. PMID 26002757 DOI: 10.1016/j.neuropsychologia.2015.04.034  0.411
2015 Shaw EE, Schultz AP, Sperling RA, Hedden T. Functional Connectivity in Multiple Cortical Networks Is Associated with Performance Across Cognitive Domains in Older Adults. Brain Connectivity. PMID 25827242 DOI: 10.1089/brain.2014.0327  0.319
2015 Hedden T, Growdon JH. Challenges and opportunities in linking brain-based biomarkers to person-specific variation in cognition: pumping up the volume. Jama Neurology. 72: 149-51. PMID 25485512 DOI: 10.1001/jamaneurol.2014.3832  0.31
2014 Hedden T, Schultz AP, Rieckmann A, Mormino EC, Johnson KA, Sperling RA, Buckner RL. Multiple Brain Markers are Linked to Age-Related Variation in Cognition. Cerebral Cortex (New York, N.Y. : 1991). PMID 25316342 DOI: 10.1093/cercor/bhu238  0.389
2014 Mormino EC, Betensky RA, Hedden T, Schultz AP, Amariglio RE, Rentz DM, Johnson KA, Sperling RA. Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals. Jama Neurology. 71: 1379-85. PMID 25222039 DOI: 10.1001/jamaneurol.2014.2031  0.433
2014 Mormino EC, Betensky RA, Hedden T, Schultz AP, Ward A, Huijbers W, Rentz DM, Johnson KA, Sperling RA. Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease. Neurology. 82: 1760-7. PMID 24748674 DOI: 10.1212/Wnl.0000000000000431  0.396
2014 Huijbers W, Mormino EC, Wigman SE, Ward AM, Vannini P, McLaren DG, Becker JA, Schultz AP, Hedden T, Johnson KA, Sperling RA. Amyloid deposition is linked to aberrant entorhinal activity among cognitively normal older adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5200-10. PMID 24719099 DOI: 10.1523/Jneurosci.3579-13.2014  0.42
2013 Ward AM, McLaren DG, Schultz AP, Chhatwal J, Boot BP, Hedden T, Sperling RA. Daytime sleepiness is associated with decreased default mode network connectivity in both young and cognitively intact elderly subjects. Sleep. 36: 1609-15. PMID 24179292 DOI: 10.5665/Sleep.3108  0.363
2013 Hedden T, Oh H, Younger AP, Patel TA. Meta-analysis of amyloid-cognition relations in cognitively normal older adults. Neurology. 80: 1341-8. PMID 23547267 DOI: 10.1212/Wnl.0B013E31828Ab35D  0.444
2013 Vannini P, Hedden T, Huijbers W, Ward A, Johnson KA, Sperling RA. The ups and downs of the posteromedial cortex: age- and amyloid-related functional alterations of the encoding/retrieval flip in cognitively normal older adults. Cerebral Cortex (New York, N.Y. : 1991). 23: 1317-28. PMID 22586140 DOI: 10.1093/Cercor/Bhs108  0.422
2012 Hedden T, Mormino EC, Amariglio RE, Younger AP, Schultz AP, Becker JA, Buckner RL, Johnson KA, Sperling RA, Rentz DM. Cognitive profile of amyloid burden and white matter hyperintensities in cognitively normal older adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16233-42. PMID 23152607 DOI: 10.1523/JNEUROSCI.2462-12.2012  0.492
2012 Vannini P, Hedden T, Becker JA, Sullivan C, Putcha D, Rentz D, Johnson KA, Sperling RA. Age and amyloid-related alterations in default network habituation to stimulus repetition. Neurobiology of Aging. 33: 1237-52. PMID 21334099 DOI: 10.1016/j.neurobiolaging.2011.01.003  0.369
2011 Becker JA, Hedden T, Carmasin J, Maye J, Rentz DM, Putcha D, Fischl B, Greve DN, Marshall GA, Salloway S, Marks D, Buckner RL, Sperling RA, Johnson KA. Amyloid-β associated cortical thinning in clinically normal elderly. Annals of Neurology. 69: 1032-42. PMID 21437929 DOI: 10.1002/Ana.22333  0.344
2010 Sperling RA, Dickerson BC, Pihlajamaki M, Vannini P, LaViolette PS, Vitolo OV, Hedden T, Becker JA, Rentz DM, Selkoe DJ, Johnson KA. Functional alterations in memory networks in early Alzheimer's disease. Neuromolecular Medicine. 12: 27-43. PMID 20069392 DOI: 10.1007/S12017-009-8109-7  0.392
2009 Hedden T, Van Dijk KR, Becker JA, Mehta A, Sperling RA, Johnson KA, Buckner RL. Disruption of functional connectivity in clinically normal older adults harboring amyloid burden. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12686-94. PMID 19812343 DOI: 10.1523/JNEUROSCI.3189-09.2009  0.31
2009 Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, Pihlajamaki M, Marshall G, Hyman BT, Selkoe DJ, Hedden T, Buckner RL, Becker JA, Johnson KA. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron. 63: 178-88. PMID 19640477 DOI: 10.1016/J.Neuron.2009.07.003  0.374
2005 Hedden T, Gabrieli JD. Healthy and pathological processes in adult development: new evidence from neuroimaging of the aging brain. Current Opinion in Neurology. 18: 740-7. PMID 16280688 DOI: 10.1097/01.Wco.0000189875.29852.48  0.46
2004 Hedden T, Gabrieli JD. Insights into the ageing mind: a view from cognitive neuroscience. Nature Reviews. Neuroscience. 5: 87-96. PMID 14735112 DOI: 10.1038/nrn1323  0.404
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