Jens Wiltfang - Publications

Affiliations: 
Department of Psychiatry and Psychotherapy Georg-August-Universität Göttingen, Göttingen, Niedersachsen, Germany 
 2002-2007 Department of Psychiatry and Psychotherapy University of Erlangen-Nuremberg, Germany 
 2007- Department of Psychiatry and Psychotherapy University of Essen, Duisburg, Nordrhein-Westfalen, Germany 

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Year Citation  Score
2021 Wendel B, Papiol S, Andlauer TFM, Zimmermann J, Wiltfang J, Spitzer C, Senner F, Schulte EC, Schmauß M, Schaupp SK, Repple J, Reininghaus E, Reimer J, Reich-Erkelenz D, Opel N, et al. A genome-wide association study of the longitudinal course of executive functions. Translational Psychiatry. 11: 386. PMID 34247186 DOI: 10.1038/s41398-021-01510-8  0.4
2021 de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, ... ... Wiltfang J, et al. Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature Communications. 12: 3417. PMID 34099642 DOI: 10.1038/s41467-021-22491-8  0.8
2021 Rauchmann BS, Ersoezlue E, Stoecklein S, Keeser D, Brosseron F, Buerger K, Dechent P, Dobisch L, Ertl-Wagner B, Fliessbach K, Haynes JD, Heneka MT, Incesoy EI, Janowitz D, Kilimann I, ... ... Wiltfang J, et al. Resting-State Network Alterations Differ between Alzheimer's Disease Atrophy Subtypes. Cerebral Cortex (New York, N.Y. : 1991). PMID 34080613 DOI: 10.1093/cercor/bhab130  0.44
2021 Hansen N, Luedecke D, Malchow B, Lipp M, Vogelgsang J, Timäus C, Zindler T, Gingele S, Kühn S, Gallinat J, Wiedemann K, Denk J, Moschny N, Fiehler J, Skripuletz T, ... ... Wiltfang J, et al. Autoantibody-associated psychiatric syndromes in children: link to adult psychiatry. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 34057596 DOI: 10.1007/s00702-021-02354-8  0.8
2021 Timäus C, Meiser M, Wiltfang J, Bandelow B, Wedekind D. Efficacy of naltrexone in borderline personality disorder, a retrospective analysis in inpatients. Human Psychopharmacology. e2800. PMID 34029405 DOI: 10.1002/hup.2800  0.32
2021 Hansen N, Singh A, Bartels C, Brosseron F, Buerger K, Cetindag AC, Dobisch L, Dechent P, Ertl-Wagner BB, Fliessbach K, Haynes JD, Heneka MT, Janowitz D, Kilimann I, Laske C, ... ... Wiltfang J, et al. Hippocampal and Hippocampal-Subfield Volumes From Early-Onset Major Depression and Bipolar Disorder to Cognitive Decline. Frontiers in Aging Neuroscience. 13: 626974. PMID 33967736 DOI: 10.3389/fnagi.2021.626974  0.44
2021 Ballarini T, Melo van Lent D, Brunner J, Schröder A, Wolfsgruber S, Altenstein S, Brosseron F, Buerger K, Dechent P, Dobisch L, Duzel E, Ertl-Wagner B, Fliessbach K, Freiesleben SD, Frommann I, ... ... Wiltfang J, et al. Mediterranean Diet, Alzheimer Disease Biomarkers and Brain Atrophy in Old Age. Neurology. PMID 33952652 DOI: 10.1212/WNL.0000000000012067  0.44
2021 Staiger A, Schroeter ML, Ziegler W, Schölderle T, Anderl-Straub S, Danek A, Duning T, Fassbender K, Fliessbach K, Jahn H, Kasper E, Kornhuber J, Landwehrmeyer B, Lauer M, Lombardi J, ... ... Wiltfang J, et al. Motor speech disorders in the nonfluent, semantic and logopenic variants of primary progressive aphasia. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 140: 66-79. PMID 33933931 DOI: 10.1016/j.cortex.2021.03.017  0.8
2021 Lombardi J, Mayer B, Semler E, Anderl-Straub S, Uttner I, Kassubek J, Diehl-Schmid J, Danek A, Levin J, Fassbender K, Fliessbach K, Schneider A, Huppertz HJ, Jahn H, Volk A, ... ... Wiltfang J, et al. Quantifying progression in primary progressive aphasia with structural neuroimaging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33787063 DOI: 10.1002/alz.12323  0.8
2020 Herdick M, Dyrba M, Fritz HJ, Altenstein S, Ballarini T, Brosseron F, Buerger K, Can Cetindag A, Dechent P, Dobisch L, Duezel E, Ertl-Wagner B, Fliessbach K, Dawn Freiesleben S, Frommann I, ... ... Wiltfang J, et al. Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer's disease spectrum. Neuroimage. Clinical. 28: 102495. PMID 33395986 DOI: 10.1016/j.nicl.2020.102495  0.44
2020 Amaefule CO, Dyrba M, Wolfsgruber S, Polcher A, Schneider A, Fliessbach K, Spottke A, Meiberth D, Preis L, Peters O, Incesoy EI, Spruth EJ, Priller J, Altenstein S, Bartels C, ... Wiltfang J, et al. Association between composite scores of domain-specific cognitive functions and regional patterns of atrophy and functional connectivity in the Alzheimer's disease spectrum. Neuroimage. Clinical. 29: 102533. PMID 33360018 DOI: 10.1016/j.nicl.2020.102533  0.44
2020 Sannemann L, Schild AK, Altenstein S, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Freiesleben SD, Glanz W, Heneka MT, Janowitz D, Kilimann I, Kobeleva X, Laske C, ... ... Wiltfang J, et al. Neuropsychiatric symptoms in at-risk groups for AD dementia and their association with worry and AD biomarkers-results from the DELCODE study. Alzheimer's Research & Therapy. 12: 131. PMID 33066827 DOI: 10.1186/s13195-020-00701-7  0.44
2020 Klafki HW, Rieper P, Matzen A, Zampar S, Wirths O, Vogelgsang J, Osterloh D, Rohdenburg L, Oberstein TJ, Jahn O, Beyer I, Lachmann I, Knölker HJ, Wiltfang J. Development and Technical Validation of an Immunoassay for the Detection of APP (Aβ) in Biological Samples. International Journal of Molecular Sciences. 21. PMID 32911706 DOI: 10.3390/Ijms21186564  0.56
2020 Wolfsgruber S, Kleineidam L, Guski J, Polcher A, Frommann I, Roeske S, Spruth EJ, Franke C, Priller J, Kilimann I, Teipel S, Buerger K, Janowitz D, Laske C, Buchmann M, ... ... Wiltfang J, et al. Minor neuropsychological deficits in patients with subjective cognitive decline. Neurology. PMID 32636322 DOI: 10.1212/Wnl.0000000000010142  0.44
2020 Fuentes M, Klostermann A, Kleineidam L, Bauer C, Schuchhardt J, Maier W, Jessen F, Frölich L, Wiltfang J, Kornhuber J, Klöppel S, Schieting V, Teipel SJ, Wagner M, Peters O. Identification of a Cascade of Changes in Activities of Daily Living Preceding Short-Term Clinical Deterioration in Mild Alzheimer's Disease via Lead-Lag Analysis. Journal of Alzheimer's Disease : Jad. PMID 32597807 DOI: 10.3233/Jad-200230  0.8
2020 Zampar S, Klafki HW, Sritharen K, Bayer TA, Wiltfang J, Rostagno A, Ghiso J, A Miles L, Wirths O. N-terminal heterogeneity of parenchymal and vascular amyloid-β deposits in Alzheimer's disease. Neuropathology and Applied Neurobiology. PMID 32497293 DOI: 10.1111/Nan.12637  0.56
2020 Wesselman LMP, van Lent DM, Schröder A, van de Rest O, Peters O, Menne F, Fuentes M, Priller J, Spruth EJ, Altenstein S, Schneider A, Fließbach K, Roeske S, Wolfsgruber S, Kleineidam L, ... ... Wiltfang J, et al. Dietary patterns are related to cognitive functioning in elderly enriched with individuals at increased risk for Alzheimer's disease. European Journal of Nutrition. PMID 32472387 DOI: 10.1007/S00394-020-02257-6  0.44
2020 Maier F, Spottke A, Bach JP, Bartels C, Buerger K, Dodel R, Fellgiebel A, Fliessbach K, Frölich L, Hausner L, Hellmich M, Klöppel S, Klostermann A, Kornhuber J, Laske C, ... ... Wiltfang J, et al. Bupropion for the Treatment of Apathy in Alzheimer Disease: A Randomized Clinical Trial. Jama Network Open. 3: e206027. PMID 32463470 DOI: 10.1001/jamanetworkopen.2020.6027  0.8
2020 Rhein C, Mühle C, Lenz B, Richter-Schmidinger T, Kogias G, Boix F, Lourdusamy A, Dörfler A, Peters O, Ramirez A, Jessen F, Maier W, Hüll M, Frölich L, Teipel S, ... Wiltfang J, et al. Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly. Brain Research Bulletin. 161: 13-20. PMID 32418901 DOI: 10.1016/J.Brainresbull.2020.05.001  0.8
2020 Kleineidam L, Chouraki V, Próchnicki T, van der Lee SJ, Madrid-Márquez L, Wagner-Thelen H, Karaca I, Weinhold L, Wolfsgruber S, Boland A, Martino Adami PV, Lewczuk P, Popp J, Brosseron F, Jansen IE, ... ... Wiltfang J, et al. PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment. Acta Neuropathologica. PMID 32166339 DOI: 10.1007/S00401-020-02138-6  0.8
2020 Dwyer DB, Kalman JL, Budde M, Kambeitz J, Ruef A, Antonucci LA, Kambeitz-Ilankovic L, Hasan A, Kondofersky I, Anderson-Schmidt H, Gade K, Reich-Erkelenz D, Adorjan K, Senner F, Schaupp S, ... ... Wiltfang J, et al. An Investigation of Psychosis Subgroups With Prognostic Validation and Exploration of Genetic Underpinnings: The PsyCourse Study. Jama Psychiatry. PMID 32049274 DOI: 10.1001/Jamapsychiatry.2019.4910  0.4
2020 Comes AL, Czamara D, Adorjan K, Anderson-Schmidt H, Andlauer TFM, Budde M, Gade K, Hake M, Kalman JL, Papiol S, Reich-Erkelenz D, Klöhn-Saghatolislam F, Schaupp SK, Schulte EC, Senner F, ... ... Wiltfang J, et al. The role of environmental stress and DNA methylation in the longitudinal course of bipolar disorder. International Journal of Bipolar Disorders. 8: 9. PMID 32048126 DOI: 10.1186/S40345-019-0176-6  0.4
2020 Besse M, Belz M, Folsche T, Vogelgsang J, Methfessel I, Steinacker P, Otto M, Wiltfang J, Zilles D. Serum neurofilament light chain (NFL) remains unchanged during electroconvulsive therapy. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 21: 148-154. PMID 31818180 DOI: 10.1080/15622975.2019.1702717  0.48
2020 Teuber-Hanselmann S, Rekowski J, Vogelgsang J, von Arnim C, Reetz K, Stang A, Jöckel KH, Wiltfang J, Esselmann H, Otto M, Tumani H, Herring A, Keyvani K. CSF and blood Kallikrein-8: a promising early biomarker for Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 91: 40-48. PMID 31371645 DOI: 10.1136/jnnp-2019-321073  0.8
2020 Basilowski M, Schönfeld B, Esser S, Jatho A, Kownatka M, Signerski-Krieger J, Esselmann H, Grabemann M, Mette C, Strunz L, Zimmermann M, Lajcsak E, Scherbaum N, Wiltfang J, Kis B, et al. From Bones to Brain: 50 Years of Star Trek and Changes in the Stigmatization of Psychological Disorders Current Psychology. 39: 1705-1714. DOI: 10.1007/S12144-018-9868-9  0.8
2019 Timäus C, Meiser M, Bandelow B, Engel KR, Paschke AM, Wiltfang J, Wedekind D. Pharmacotherapy of borderline personality disorder: what has changed over two decades? A retrospective evaluation of clinical practice. Bmc Psychiatry. 19: 393. PMID 31830934 DOI: 10.1186/S12888-019-2377-Z  0.32
2019 Ballarini T, Albrecht F, Mueller K, Jech R, Diehl-Schmid J, Fliessbach K, Kassubek J, Lauer M, Fassbender K, Schneider A, Synofzik M, Wiltfang J, Otto M, et al. Disentangling brain functional network remodeling in corticobasal syndrome - A multimodal MRI study. Neuroimage. Clinical. 25: 102112. PMID 31821953 DOI: 10.1016/J.Nicl.2019.102112  0.48
2019 Raue S, Wedekind D, Wiltfang J, Schmidt U. The Role of Proopiomelanocortin and α-Melanocyte-Stimulating Hormone in the Metabolic Syndrome in Psychiatric Disorders: A Narrative Mini-Review. Frontiers in Psychiatry. 10: 834. PMID 31798479 DOI: 10.3389/Fpsyt.2019.00834  0.32
2019 Teipel SJ, Kuper-Smith JO, Bartels C, Brosseron F, Buchmann M, Buerger K, Catak C, Janowitz D, Dechent P, Dobisch L, Ertl-Wagner B, Fließbach K, Haynes JD, Heneka MT, Kilimann I, ... ... Wiltfang J, et al. Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer's Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness. Journal of Alzheimer's Disease : Jad. PMID 31594223 DOI: 10.3233/Jad-190446  0.4
2019 Jain G, Stuendl A, Rao P, Berulava T, Pena Centeno T, Kaurani L, Burkhardt S, Delalle I, Kornhuber J, Hüll M, Maier W, Peters O, Esselmann H, Schulte C, Deuschle C, ... ... Wiltfang J, et al. A combined miRNA-piRNA signature to detect Alzheimer's disease. Translational Psychiatry. 9: 250. PMID 31591382 DOI: 10.1038/S41398-019-0579-2  0.8
2019 van Maurik IS, Vos SJ, Bos I, Bouwman FH, Teunissen CE, Scheltens P, Barkhof F, Frolich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Nobili F, Frisoni GB, et al. Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study. The Lancet. Neurology. PMID 31526625 DOI: 10.1016/S1474-4422(19)30283-2  0.8
2019 Bainbridge WA, Berron D, Schütze H, Cardenas-Blanco A, Metzger C, Dobisch L, Bittner D, Glanz W, Spottke A, Rudolph J, Brosseron F, Buerger K, Janowitz D, Fliessbach K, Heneka M, ... ... Wiltfang J, et al. Memorability of photographs in subjective cognitive decline and mild cognitive impairment: Implications for cognitive assessment. Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 610-618. PMID 31517023 DOI: 10.1016/J.Dadm.2019.07.005  0.44
2019 Karsak M, Glebov K, Scheffold M, Bajaj T, Kawalia A, Karaca I, Rading S, Kornhuber J, Peters O, Diez-Fairen M, Frölich L, Hüll M, Wiltfang J, Scherer M, Riedel-Heller S, et al. A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2. Human Mutation. PMID 31464095 DOI: 10.1002/Humu.23904  0.8
2019 Comes AL, Senner F, Budde M, Adorjan K, Anderson-Schmidt H, Andlauer TFM, Gade K, Hake M, Heilbronner U, Kalman JL, Reich-Erkelenz D, Klöhn-Saghatolislam F, Schaupp SK, Schulte EC, Juckel G, ... ... Wiltfang J, et al. The genetic relationship between educational attainment and cognitive performance in major psychiatric disorders. Translational Psychiatry. 9: 210. PMID 31462630 DOI: 10.1038/S41398-019-0547-X  0.4
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Wiltfang J, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7  0.48
2019 Miebach L, Wolfsgruber S, Polcher A, Peters O, Menne F, Luther K, Incesoy E, Priller J, Spruth E, Altenstein S, Buerger K, Catak C, Janowitz D, Perneczky R, Utecht J, ... ... Wiltfang J, et al. Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study. Alzheimer's Research & Therapy. 11: 66. PMID 31366409 DOI: 10.1186/S13195-019-0515-Y  0.44
2019 Brueggen K, Dyrba M, Cardenas-Blanco A, Schneider A, Fliessbach K, Buerger K, Janowitz D, Peters O, Menne F, Priller J, Spruth E, Wiltfang J, Vukovich R, Laske C, Buchmann M, et al. Structural integrity in subjective cognitive decline, mild cognitive impairment and Alzheimer's disease based on multicenter diffusion tensor imaging. Journal of Neurology. PMID 31227891 DOI: 10.1007/S00415-019-09429-3  0.44
2019 Vogelgsang J, Vukovich R, Wedekind D, Wiltfang J. Higher Level of Mismatch in APOEε4 Carriers for Amyloid-Beta Peptide Alzheimer's Disease Biomarkers in Cerebrospinal Fluid. Asn Neuro. 11: 1759091419845524. PMID 31104469 DOI: 10.1177/1759091419845524  0.32
2019 Albrecht F, Mueller K, Ballarini T, Lampe L, Diehl-Schmid J, Fassbender K, Fliessbach K, Jahn H, Jech R, Kassubek J, Kornhuber J, Landwehrmeyer B, Lauer M, Ludolph AC, Lyros E, ... ... Wiltfang J, et al. Unraveling corticobasal syndrome and alien limb syndrome with structural brain imaging. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 117: 33-40. PMID 30927559 DOI: 10.1016/J.Cortex.2019.02.015  0.8
2019 Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, ... ... Wiltfang J, et al. The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. Molecular Psychiatry. PMID 30899092 DOI: 10.1038/S41380-019-0404-6  0.44
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Wiltfang J, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.48
2019 Santos JRF, Bauer C, Schuchhardt J, Wedekind D, Waniek K, Lachmann I, Wiltfang J, Vogelgsang J. Validation of a prototype tau Thr231 phosphorylation CSF ELISA as a potential biomarker for Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 30767082 DOI: 10.1007/S00702-019-01982-5  0.44
2019 Hornung K, Zampar S, Engel N, Klafki H, Liepold T, Bayer TA, Wiltfang J, Jahn O, Wirths O. N-Terminal Truncated Aβ4-42 Is a Substrate for Neprilysin Degradation in vitro and in vivo. Journal of Alzheimer's Disease : Jad. 67: 849-858. PMID 30664509 DOI: 10.3233/Jad-181134  0.56
2019 Wolfsgruber S, Molinuevo JL, Wagner M, Teunissen CE, Rami L, Coll-Padrós N, Bouwman FH, Slot RER, Wesselman LMP, Peters O, Luther K, Buerger K, Priller J, Laske C, Teipel S, ... ... Wiltfang J, et al. Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples. Alzheimer's Research & Therapy. 11: 8. PMID 30654834 DOI: 10.1186/S13195-018-0463-Y  0.44
2019 Anderson-Schmidt H, Gade K, Malzahn D, Papiol S, Budde M, Heilbronner U, Reich-Erkelenz D, Adorjan K, Kalman JL, Senner F, Comes AL, Flatau L, Gryaznova A, Hake M, Reitt M, ... ... Wiltfang J, et al. The influence of religious activity and polygenic schizophrenia risk on religious delusions in schizophrenia. Schizophrenia Research. PMID 30611655 DOI: 10.1016/J.Schres.2018.12.025  0.4
2019 Meiberth DU, Hu X, Schild A, Spottke A, Brosseron F, Buerger K, Fliessbach K, Heneka MT, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Teipel SJ, Wiltfang J, et al. P1-339: Cortical Thickness And Alzheimer'S Related Biomarkers In Subjective Cognitive Decline - Data From The Delcode-Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.894  0.44
2019 Miebach L, Kleineidam L, Peters O, Priller J, Buerger K, Perneczky R, Laske C, Schneider A, Heneka MT, Spottke A, Teipel SJ, Wiltfang J, Düzel E, Jessen F, Wagner M. P1-326: Anosognosia And Csf-Biomarkers In Nondemented Older Adults: Results From The Delcode-Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.881  0.44
2019 Hu X, Lee HL, Spottke A, Peters O, Priller J, Bürger K, Teipel SJ, Laske C, Wiltfang J, Düzel E, Jessen F. Ic-P-122: Alterations Of Intrinsic Connectivity In Posterior Default Mode Network Across At Risk Stages Of Alzheimer'S Dementia Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3980  0.44
2019 Sannemann L, Spottke A, Brosseron F, Buerger K, Fließbach K, Heneka MT, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Teipel SJ, Wiltfang J, Wagner M, Düzel E, et al. P4-236: The Association Of Ad Pathology With Neuropsychiatric Symptoms And Worry In Subjective Cognitive Decline - Data From The Delcode Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3899  0.44
2019 Wolfsgruber S, Kleineidam L, Peters O, Buerger K, Ewers M, Priller J, Laske C, Teipel SJ, Schneider A, Spottke A, Heneka MT, Wiltfang J, Jessen F, Wagner M. P3-447: Minor Neuropsychological Deficits In Cognitively Normal Older Individuals With Subjective Cognitive Decline: Results From The Delcode Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3481  0.44
2019 Marzban EN, Teipel SJ, Buerger K, Fliessbach K, Heneka MT, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Spottke A, Wagner M, Wiltfang J, Düzel E, Jessen F, et al. P3-361: Explainable Convolutional Networks And Multimodal Imaging Data: The Next Step Towards Using Artificial Intelligence As Diagnostic Tool For Early Detection Of Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3394  0.44
2019 Metzger CD, Dyrba M, Bittner D, Hu X, Teipel SJ, Grothe MJ, Peters O, Menne F, Fuentes M, Priller J, Spruth E, Franke C, Schneider A, Fliessbach K, Kofler B, ... Wiltfang J, et al. P1-407: Relationship Between Global Connectivity, Amyloid And Tau In Different Stages During The Development Of Alzheimer'S Disease As Demonstrated In The Dzne Delcode Cohort Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.1012  0.44
2018 Düzel E, Berron D, Schütze H, Cardenas-Blanco A, Metzger C, Betts M, Ziegler G, Chen Y, Dobisch L, Bittner D, Glanz W, Reuter M, Spottke A, Rudolph J, Brosseron F, ... ... Wiltfang J, et al. CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 782-790. PMID 30555890 DOI: 10.1016/J.Dadm.2018.10.003  0.44
2018 Shahpasand-Kroner H, Klafki HW, Bauer C, Schuchhardt J, Hüttenrauch M, Stazi M, Bouter C, Wirths O, Vogelgsang J, Wiltfang J. A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer's disease. Alzheimer's Research & Therapy. 10: 121. PMID 30526652 DOI: 10.1186/S13195-018-0448-X  0.56
2018 Walter S, Jumpertz T, Hüttenrauch M, Ogorek I, Gerber H, Storck SE, Zampar S, Dimitrov M, Lehmann S, Lepka K, Berndt C, Wiltfang J, Becker-Pauly C, Beher D, Pietrzik CU, et al. The metalloprotease ADAMTS4 generates N-truncated Aβ4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease. Acta Neuropathologica. PMID 30426203 DOI: 10.1007/S00401-018-1929-5  0.32
2018 Espinosa A, Hernández-Olasagarre B, Moreno-Grau S, Kleineidam L, Heilmann-Heimbach S, Hernández I, Wolfsgruber S, Wagner H, Rosende-Roca M, Mauleón A, Vargas L, Lafuente A, Rodríguez-Gómez O, Abdelnour C, Gil S, ... ... Wiltfang J, et al. Exploring Genetic Associations of Alzheimer's Disease Loci With Mild Cognitive Impairment Neurocognitive Endophenotypes. Frontiers in Aging Neuroscience. 10: 340. PMID 30425636 DOI: 10.3389/Fnagi.2018.00340  0.8
2018 Hüttenrauch M, Ogorek I, Klafki H, Otto M, Stadelmann C, Weggen S, Wiltfang J, Wirths O. Glycoprotein NMB: a novel Alzheimer's disease associated marker expressed in a subset of activated microglia. Acta Neuropathologica Communications. 6: 108. PMID 30340518 DOI: 10.1186/S40478-018-0612-3  0.56
2018 Steinacker P, Anderl-Straub S, Diehl-Schmid J, Semler E, Uttner I, von Arnim CAF, Barthel H, Danek A, Fassbender K, Fliessbach K, Foerstl H, Grimmer T, Huppertz HJ, Jahn H, Kassubek J, ... ... Wiltfang J, et al. Serum neurofilament light chain in behavioral variant frontotemporal dementia. Neurology. PMID 30209235 DOI: 10.1212/WNL.0000000000006318  0.8
2018 Bibl M, Gallus M, Welge V, Esselmann H, Wolf S, Rüther E, Wiltfang J. Correction to: Cerebrospinal fluid amyloid-β 2-42 is decreased in Alzheimer's, but not in frontotemporal dementia. Journal of Neural Transmission (Vienna, Austria : 1996). 125: 1515-1516. PMID 30159607 DOI: 10.1007/S00702-018-1914-0  0.8
2018 Budde M, Anderson-Schmidt H, Gade K, Reich-Erkelenz D, Adorjan K, Kalman JL, Senner F, Papiol S, Andlauer TFM, Comes AL, Schulte EC, Klöhn-Saghatolislam F, Gryaznova A, Hake M, Bartholdi K, ... ... Wiltfang J, et al. A longitudinal approach to biological psychiatric research: The PsyCourse study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 30070057 DOI: 10.1002/Ajmg.B.32639  0.4
2018 Joachim LK, Frölich L, Rüther E, Wiltfang J, Maier W, Kornhuber J, Bauer C, Heuser I, Peters O. Correlation of CSF- and MRI-Biomarkers and Progression of Cognitive Decline in an Open Label MCI Trial. The Journal of Prevention of Alzheimer's Disease. 5: 202-206. PMID 29972214 DOI: 10.14283/jpad.2018.5  0.8
2018 Kalman JL, Papiol S, Forstner AJ, Heilbronner U, Degenhardt F, Strohmaier J, Adli M, Adorjan K, Akula N, Alda M, Anderson-Schmidt H, Andlauer TF, Anghelescu IG, Ardau R, Arias B, ... ... Wiltfang J, et al. Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study. Bipolar Disorders. PMID 29956436 DOI: 10.1111/Bdi.12659  0.4
2018 Denk J, Oberhauser F, Kornhuber J, Wiltfang J, Fassbender K, Schroeter ML, Volk AE, Diehl-Schmid J, Prudlo J, Danek A, Landwehrmeyer B, Lauer M, Otto M, Jahn H. Specific serum and CSF microRNA profiles distinguish sporadic behavioural variant of frontotemporal dementia compared with Alzheimer patients and cognitively healthy controls. Plos One. 13: e0197329. PMID 29746584 DOI: 10.1371/Journal.Pone.0197329  0.8
2018 Mattsson N, Groot C, Jansen WJ, Landau S, Villemagne V, Engelborghs S, Mintun M, Lleo A, Molinuevo JL, Jagust W, Frisoni GB, Ivanoiu A, Chételat G, Resende de Oliveira C, Rodrigue KM, ... ... Wiltfang J, et al. Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29601787 DOI: 10.1016/J.Jalz.2018.02.009  0.8
2018 Teunissen CE, Otto M, Engelborghs S, Herukka SK, Lehmann S, Lewczuk P, Lleó A, Perret-Liaudet A, Tumani H, Turner MR, Verbeek MM, Wiltfang J, Zetterberg H, Parnetti L, Blennow K. White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation. Alzheimer's Research & Therapy. 10: 30. PMID 29544527 DOI: 10.1186/S13195-018-0359-X  0.8
2018 Vogelgsang J, Wiltfang J, Klafki HW. Validation of a Chemiluminescence Immunoassay for Measuring Amyloid-β in Human Blood Plasma. Methods in Molecular Biology (Clifton, N.J.). 1750: 111-124. PMID 29512068 DOI: 10.1007/978-1-4939-7704-8_7  0.56
2018 Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, ... ... Wiltfang J, et al. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain : a Journal of Neurology. PMID 29462334 DOI: 10.1093/Brain/Awy008  0.44
2018 Vogelgsang J, Wedekind D, Bouter C, Klafki HW, Wiltfang J. Reproducibility of Alzheimer's Disease Cerebrospinal Fluid-Biomarker Measurements under Clinical Routine Conditions. Journal of Alzheimer's Disease : Jad. 62: 203-212. PMID 29439341 DOI: 10.3233/Jad-170793  0.56
2018 Jessen F, Spottke A, Boecker H, Brosseron F, Buerger K, Catak C, Fliessbach K, Franke C, Fuentes M, Heneka MT, Janowitz D, Kilimann I, Laske C, Menne F, Nestor P, ... ... Wiltfang J, et al. Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE). Alzheimer's Research & Therapy. 10: 15. PMID 29415768 DOI: 10.1186/S13195-017-0314-2  0.44
2018 Meiberth DU, Hu X, Schild A, Spottke A, Brosseron F, Buerger K, Fliessbach K, Heneka MT, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Teipel SJ, Wiltfang J, et al. P1-379: Cortical Thinning In Subjective Cognitive Decline With And Without Ad Pathology: Data From The Delcode Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.387  0.44
2018 Miebach L, Wolfsgruber S, Frommann I, Roeske S, Oliver P, Buerger K, Nestor P, Ewers M, Laske C, Priller J, Schneider A, Spottke A, Heneka M, Teipel SJ, Wiltfang J, et al. F4-08-04: Subjective Cognitive Decline, As Measured With A Structured Interview, Is Related To Amyloid Pathology In Cognitively Healthy Older Adults Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2895  0.4
2018 Schipke CG, Menne F, Teipel SJ, Buerger K, Schneider A, Priller J, Christoph L, Wiltfang J, Spottke A, Heneka M, Brosseron F, Wagner M, Düzel E, Jessen F, Peters O. P4-068: Levels Of The Astrocyte-Derived Proteins Gfap And S100B In The Cerebrospinal Fluid Of Healthy Individuals And Alzheimer'S Disease Patients At Different Disease Stages Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2471  0.44
2018 Roeske S, Wolfsgruber S, Kleineidam L, Zulka L, Buerger K, Ewers M, Laske C, Nestor P, Peters O, Priller J, Schneider A, Spottke A, Ramirez A, Heneka M, Teipel SJ, ... Wiltfang J, et al. P3-591: A German Version Of The Lifetime Of Experiences Questionnaire (Leq) To Measure Cognitive Reserve: Validation Results From The Delcode Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1957  0.44
2018 Sannemann L, Hu X, Spottke A, Brosseron F, Buerger K, Fliessbach K, Heneka M, Kilimann I, Laske C, Peters O, Priller J, Schneider A, Teipel SJ, Wiltfang J, Wagner M, et al. P3-327: Neuropsychiatric Symptoms In At-Risk Groups For Ad Dementia And Their Relation To Ad Biomarkers: Data From The Delcode Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1688  0.44
2018 Brueggen K, Dyrba M, Cardenas-Blanco A, Nestor P, Schneider A, Buerger K, Peters O, Priller J, Wiltfang J, Laske C, Wagner M, Spottke A, Düzel E, Jessen F, Teipel SJ. Ic-P-155: Structural Integrity In Subjective Cognitive Decline, Mild Cognitive Impairment And Alzheimer'S Disease Based On Multicenter Diffusion Tensor Imaging: Results From The Delcode Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1148  0.44
2018 Kuper-Smith JO, Dyrba M, Brueggen K, Cardenas-Blanco A, Spottke A, Nestor P, Buerger K, Schneider A, Peters O, Priller J, Wiltfang J, Laske C, Düzel E, Jessen F, Teipel SJ. Ic-P-163: Microstructural Changes In Alzheimer'S Disease, Mild Cognitive Impairment, And Subjective Cognitive Decline Based On Multicenter Diffusion Tensor Imaging: A Tbss Analysis Of Delcode Data Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1139  0.44
2018 Wolfsgruber S, Kleineidam L, Roeske S, Zulka L, Buerger K, Ewers M, Christoph L, Peters O, Priller J, Nestor P, Schneider A, Spottke A, Ramirez A, Heneka M, Wiltfang J, et al. P1-028: Occupational Cognitive Requirements Are An Important Proxy Measure Of Cognitive Reserve: Evidence From The Agecode And Delcode Studies Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.029  0.44
2017 Jansen WJ, Ossenkoppele R, Tijms BM, Fagan AM, Hansson O, Klunk WE, van der Flier WM, Villemagne VL, Frisoni GB, Fleisher AS, Lleó A, Mintun MA, Wallin A, Engelborghs S, Na DL, ... ... Wiltfang J, et al. Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia. Jama Psychiatry. PMID 29188296 DOI: 10.1001/Jamapsychiatry.2017.3391  0.8
2017 Lewczuk P, Riederer P, O'Bryant SE, Verbeek MM, Dubois B, Visser PJ, Jellinger KA, Engelborghs S, Ramirez A, Parnetti L, Jack CR, Teunissen CE, Hampel H, Lleó A, Jessen F, ... ... Wiltfang J, et al. Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-85. PMID 29076399 DOI: 10.1080/15622975.2017.1375556  0.8
2017 Frölich L, Peters O, Lewczuk P, Gruber O, Teipel SJ, Gertz HJ, Jahn H, Jessen F, Kurz A, Luckhaus C, Hüll M, Pantel J, Reischies FM, Schröder J, Wagner M, ... ... Wiltfang J, et al. Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer's dementia. Alzheimer's Research & Therapy. 9: 84. PMID 29017593 DOI: 10.1186/S13195-017-0301-7  0.8
2017 Wirths O, Walter S, Kraus I, Klafki HW, Stazi M, Oberstein TJ, Ghiso J, Wiltfang J, Bayer TA, Weggen S. N-truncated Aβ4-x peptides in sporadic Alzheimer's disease cases and transgenic Alzheimer mouse models. Alzheimer's Research & Therapy. 9: 80. PMID 28978359 DOI: 10.1186/S13195-017-0309-Z  0.56
2017 Müller S, Preische O, Göpfert JC, Yañez VAC, Joos TO, Boecker H, Düzel E, Falkai P, Priller J, Buerger K, Catak C, Janowitz D, Heneka MT, Brosseron F, Nestor P, ... ... Wiltfang J, et al. Tau plasma levels in subjective cognitive decline: Results from the DELCODE study. Scientific Reports. 7: 9529. PMID 28842559 DOI: 10.1038/S41598-017-08779-0  0.44
2017 Wolfsgruber S, Polcher A, Koppara A, Kleineidam L, Frölich L, Peters O, Hüll M, Rüther E, Wiltfang J, Maier W, Kornhuber J, Lewczuk P, Jessen F, Wagner M. Cerebrospinal Fluid Biomarkers and Clinical Progression in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 28527210 DOI: 10.3233/Jad-161252  0.8
2017 Bos I, Vos SJ, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Engelborghs S, Niemantsverdriet E, De Roeck EE, Tsolaki M, Freund-Levi Y, Johannsen P, Vandenberghe R, et al. The frequency and influence of dementia risk factors in prodromal Alzheimer's disease. Neurobiology of Aging. 56: 33-40. PMID 28482212 DOI: 10.1016/J.Neurobiolaging.2017.03.034  0.8
2017 Vogelgsang J, Klafki H, Wedekind D, Bouter C, Wiltfang J. Reproducibility of Alzheimer's Disease CSF-Biomarker Measurements under Clinical Routine Conditions Pharmacopsychiatry. 50. DOI: 10.1055/S-0037-1606415  0.56
2017 Bainbridge WA, Berron D, Schütze H, Jessen F, Spottke A, Nestor P, Buerger K, Schneider A, Peters O, Priller J, Wiltfang J, Laske C, Teipel SJ, Baker CI, Düzel E. What Is Memorable Is Conserved Across Healthy Aging, Early Alzheimer’S Disease, And Neural Networks Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.189  0.44
2016 Jordan W, Dobrowolny H, Bahn S, Bernstein HG, Brigadski T, Frodl T, Isermann B, Lessmann V, Pilz J, Rodenbeck A, Schiltz K, Schwedhelm E, Tumani H, Wiltfang J, Guest PC, et al. Oxidative stress in drug-naïve first episode patients with schizophrenia and major depression: effects of disease acuity and potential confounders. European Archives of Psychiatry and Clinical Neuroscience. PMID 27913877 DOI: 10.1007/S00406-016-0749-7  0.36
2016 Wiltfang J, Lewczuk P, Otto M. Biomarker bei Demenzen und anderen neurodegenerativen Erkrankungen: Aktuelle Entwicklungen Nervenarzt. 87: 1305-1309. PMID 27844089 DOI: 10.1007/S00115-016-0238-2  0.8
2016 Gronewold J, Todica O, Klafki HW, Seidel UK, Kaltwasser B, Wiltfang J, Kribben A, Bruck H, Hermann DM. Association of Plasma β-Amyloid with Cognitive Performance and Decline in Chronic Kidney Disease. Molecular Neurobiology. PMID 27796755 DOI: 10.1007/s12035-016-0243-2  0.56
2016 Radenbach K, Retzlik J, Meyer-Rötz SH, Wolff-Menzler C, Wolff J, Esselmann H, Godemann F, Riemenschneider M, Wiltfang J, Jessen F. [Guideline-adherent inpatient psychiatric psychotherapeutic treatment of behavioral and psychological symptoms of dementia : Normative definition of personnel requirements]. Der Nervenarzt. PMID 27581115 DOI: 10.1007/S00115-016-0195-9  0.8
2016 Klafki HW, Hafermann H, Bauer C, Haussmann U, Kraus I, Schuchhardt J, Muck S, Scherbaum N, Wiltfang J. Validation of a Commercial Chemiluminescence Immunoassay for the Simultaneous Measurement of Three Different Amyloid-β Peptides in Human Cerebrospinal Fluid and Application to a Clinical Cohort. Journal of Alzheimer's Disease : Jad. PMID 27567847 DOI: 10.3233/Jad-160398  0.56
2016 Halbgebauer S, Nagl M, Klafki H, Haußmann U, Steinacker P, Oeckl P, Kassubek J, Pinkhardt E, Ludolph AC, Soininen H, Herukka SK, Wiltfang J, Otto M. Modified serpinA1 as risk marker for Parkinson's disease dementia: Analysis of baseline data. Scientific Reports. 6: 26145. PMID 27184740 DOI: 10.1038/Srep26145  0.56
2016 Beyer I, Rezaei-Ghaleh N, Klafki HW, Jahn O, Haußmann U, Wiltfang J, Zweckstetter M, Knölker HJ. Solid-Phase Synthesis and Characterization of N-Terminally Elongated Aβ-3-x -Peptides. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27167300 DOI: 10.1002/Chem.201600892  0.56
2016 Hüttenrauch M, Brauß A, Kurdakova A, Borgers H, Klinker F, Liebetanz D, Salinas-Riester G, Wiltfang J, Klafki HW, Wirths O. Physical activity delays hippocampal neurodegeneration and rescues memory deficits in an Alzheimer disease mouse model. Translational Psychiatry. 6. PMID 27138799 DOI: 10.1038/Tp.2016.65  0.56
2016 Bey K, Wolfsgruber S, Karaca I, Wagner H, Lardenoije R, Becker J, Milz E, Kornhuber J, Peters O, Frölich L, Hüll M, Rüther E, Wiltfang J, Riedel-Heller S, Scherer M, et al. No association of the variant rs11887120 in DNMT3A with cognitive decline in individuals with mild cognitive impairment. Epigenomics. PMID 27092400 DOI: 10.2217/epi-2015-0014  0.8
2016 Peters O, Heuser I, Frölich L, Rüther E, Rienhoff O, Kornhuber J, Wiltfang J, Maier W. [Dementia Competence Network. Results and outlook]. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 59: 438-43. PMID 26979717 DOI: 10.1007/S00103-016-2314-Y  0.8
2016 Lacour A, Espinosa A, Louwersheimer E, Heilmann S, Hernández I, Wolfsgruber S, Fernández V, Wagner H, Rosende-Roca M, Mauleón A, Moreno-Grau S, Vargas L, Pijnenburg YA, Koene T, Rodríguez-Gómez O, ... ... Wiltfang J, et al. Genome-wide significant risk factors for Alzheimer's disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment. Molecular Psychiatry. PMID 26976043 DOI: 10.1038/Mp.2016.18  0.8
2016 Lelental N, Brandner S, Kofanova O, Blennow K, Zetterberg H, Andreasson U, Engelborghs S, Mroczko B, Gabryelewicz T, Teunissen C, Mollenhauer B, Parnetti L, Chiasserini D, Molinuevo JL, Perret-Liaudet A, ... ... Wiltfang J, et al. Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics. Journal of Alzheimer's Disease : Jad. PMID 26967210 DOI: 10.3233/Jad-150883  0.8
2016 Reinert J, Richard BC, Klafki HW, Friedrich B, Bayer TA, Wiltfang J, Kovacs GG, Ingelsson M, Lannfelt L, Paetau A, Bergquist J, Wirths O. Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer's disease and transgenic mouse models. Acta Neuropathologica Communications. 4: 24. PMID 26955942 DOI: 10.1186/S40478-016-0294-7  0.56
2016 Louwersheimer E, Wolfsgruber S, Espinosa A, Lacour A, Heilmann-Heimbach S, Alegret M, Hernández I, Rosende-Roca M, Tárraga L, Boada M, Kornhuber J, Peters O, Frölich L, Hüll M, Rüther E, ... Wiltfang J, et al. Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26921674 DOI: 10.1016/J.Jalz.2016.01.006  0.8
2016 Nabers A, Ollesch J, Schartner J, Kötting C, Genius J, Hafermann H, Klafki H, Gerwert K, Wiltfang J. Amyloid-β-Secondary Structure Distribution in Cerebrospinal Fluid and Blood Measured by an Immuno-Infrared-Sensor: A Biomarker Candidate for Alzheimer's Disease. Analytical Chemistry. 88: 2755-62. PMID 26828829 DOI: 10.1021/acs.analchem.5b04286  0.56
2016 van Waalwijk van Doorn LJ, Koel-Simmelink MJ, Haußmann U, Klafki H, Struyfs H, Linning P, Knölker HJ, Twaalfhoven H, Kuiperij HB, Engelborghs S, Scheltens P, Verbeek MM, Vanmechelen E, Wiltfang J, Teunissen CE. Validation of soluble APP assays as diagnostic CSF biomarkers for neurodegenerative diseases. Journal of Neurochemistry. PMID 26748905 DOI: 10.1111/Jnc.13527  0.8
2016 Nabers A, Ollesch J, Schartner J, Kötting C, Genius J, Haußmann U, Klafki H, Wiltfang J, Gerwert K. An infrared sensor analysing label-free the secondary structure of the Abeta peptide in presence of complex fluids. Journal of Biophotonics. 9: 224-34. PMID 25808829 DOI: 10.1002/Jbio.201400145  0.56
2016 Zerr I, Bandelow B, Wedekind D, Schneider A, Radenbach K, Wiltfang J, Bähr M. Neuropsychiatric Disorders and Dementia: An Interdisciplinary Concept Aktuelle Neurologie. 43: 369-371. DOI: 10.1055/S-0042-106719  0.32
2016 Suppa P, Schipke CG, Spies L, Wiltfang J, Peters O. P4-174: Evaluation of Cutoff Values For Fully Automated Hippocampus Volumetry With Fsl-First For Prediction Of Alzheimer's Disease Dementia In Mci Subjects Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.2266  0.44
2016 Bos I, Vos S, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Engelborghs S, Niemantsverdriet E, Roeck ED, Tsolaki M, Freund-Levi Y, Johannsen P, Vandenberghe R, et al. Prevalence of vasculare risk factors in different stages of prodromal Alzheimer’s disease and its influence on cognitive decline Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.2213  0.8
2015 Peters O, Fuentes M, Joachim LK, Jessen F, Luckhaus C, Kornhuber J, Pantel J, Hüll M, Schmidtke K, Rüther E, Möller HJ, Kurz A, Wiltfang J, Maier W, Wiese B, et al. Combined treatment with memantine and galantamine-CR compared with galantamine-CR only in antidementia drug naïve patients with mild-to-moderate Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 1: 198-204. PMID 29854939 DOI: 10.1016/J.Trci.2015.10.001  0.8
2015 Lewczuk P, Kornhuber J, Toledo JB, Trojanowski JQ, Knapik-Czajka M, Peters O, Wiltfang J, Shaw LM. Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer's Disease in Pre-Dementia Subjects. Journal of Alzheimer's Disease : Jad. 49: 887. PMID 26682863 DOI: 10.3233/JAD-159006  0.8
2015 Savastano A, Klafki H, Haußmann U, Oberstein TJ, Muller P, Wirths O, Wiltfang J, Bayer TA. N-Truncated Aβ2-X Starting with Position Two in Sporadic Alzheimer's Disease Cases and Two Alzheimer Mouse Models. Journal of Alzheimer's Disease : Jad. 49: 101-10. PMID 26529393 DOI: 10.3233/Jad-150394  0.8
2015 Koppara A, Wolfsgruber S, Kleineidam L, Schmidtke K, Frölich L, Kurz A, Schulz S, Hampel H, Heuser I, Peters O, Reischies FM, Jahn H, Luckhaus C, Hüll M, Gertz HJ, ... ... Wiltfang J, et al. The Latent Dementia Phenotype δ is Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Predicts Conversion to Dementia in Subjects with Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 26484902 DOI: 10.3233/Jad-150257  0.8
2015 Savastano A, Klafki H, Haußmann U, Oberstein TJ, Muller P, Wirths O, Wiltfang J, Bayer TA. N-Truncated Aβ 2-X Starting with Position Two in Sporadic Alzheimer's Disease Cases and Two Alzheimer Mouse Models. Journal of Alzheimer's Disease : Jad. PMID 26444772 DOI: 10.3233/JAD-150349  0.56
2015 Lewczuk P, Kornhuber J, Toledo JB, Trojanowski JQ, Knapik-Czajka M, Peters O, Wiltfang J, Shaw LM. Validation of the Erlangen Score Algorithm for the Prediction of the Development of Dementia due to Alzheimer's Disease in Pre-Dementia Subjects. Journal of Alzheimer's Disease : Jad. 48: 433-41. PMID 26402007 DOI: 10.3233/Jad-150342  0.8
2015 Kraus I, Besong Agbo D, Otto M, Wiltfang J, Klafki H. Detection and Differentiation of Threonine- and Tyrosine-Monophosphorylated Forms of ERK1/2 by Capillary Isoelectric Focusing-Immunoassay. Scientific Reports. 5: 12767. PMID 26235103 DOI: 10.1038/Srep12767  0.56
2015 Mette C, Grabemann M, Zimmermann M, Strunz L, Scherbaum N, Wiltfang J, Kis B. No Clear Association between Impaired Short-Term or Working Memory Storage and Time Reproduction Capacity in Adult ADHD Patients. Plos One. 10: e0133714. PMID 26221955 DOI: 10.1371/journal.pone.0133714  0.8
2015 Gronewold J, Klafki HW, Baldelli E, Kaltwasser B, Seidel UK, Todica O, Volsek M, Haußmann U, Wiltfang J, Kribben A, Bruck H, Hermann DM. Factors Responsible for Plasma β-Amyloid Accumulation in Chronic Kidney Disease. Molecular Neurobiology. PMID 26019016 DOI: 10.1007/s12035-015-9218-y  0.56
2015 Morgen K, Schneider M, Frölich L, Tost H, Plichta MM, Kölsch H, Rakebrandt F, Rienhoff O, Jessen F, Peters O, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, ... ... Wiltfang J, et al. Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer's disease: a voxel-based lesion mapping study. Alzheimer's Research & Therapy. 7: 27. PMID 25984242 DOI: 10.1186/S13195-015-0111-8  0.8
2015 Moreno F, Rabinovici GD, Karydas A, Miller Z, Hsu SC, Legati A, Fong J, Schonhaut D, Esselmann H, Watson C, Stephens ML, Kramer J, Wiltfang J, Seeley WW, Miller BL, et al. A novel mutation P112H in the TARDBP gene associated with frontotemporal lobar degeneration without motor neuron disease and abundant neuritic amyloid plaques. Acta Neuropathologica Communications. 3: 19. PMID 25853458 DOI: 10.1186/S40478-015-0190-6  0.8
2015 Heilmann S, Drichel D, Clarimon J, Fernández V, Lacour A, Wagner H, Thelen M, Hernández I, Fortea J, Alegret M, Blesa R, Mauleón A, Roca MR, Kornhuber J, Peters O, ... ... Wiltfang J, et al. PLD3 in non-familial Alzheimer's disease. Nature. 520: E3-5. PMID 25832411 DOI: 10.1038/Nature14039  0.8
2015 Wolfsgruber S, Jessen F, Koppara A, Kleineidam L, Schmidtke K, Frölich L, Kurz A, Schulz S, Hampel H, Heuser I, Peters O, Reischies FM, Jahn H, Luckhaus C, Hüll M, ... ... Wiltfang J, et al. Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI. Neurology. 84: 1261-8. PMID 25716354 DOI: 10.1212/Wnl.0000000000001399  0.8
2015 Vos SJ, Verhey F, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Nobili F, Morbelli S, Frisoni GB, Drzezga A, Didic M, van Berckel BN, Simmons A, et al. Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage. Brain : a Journal of Neurology. 138: 1327-38. PMID 25693589 DOI: 10.1093/Brain/Awv029  0.8
2015 Louwersheimer E, Ramirez A, Cruchaga C, Becker T, Kornhuber J, Peters O, Heilmann S, Wiltfang J, Jessen F, Visser PJ, Scheltens P, Pijnenburg YA, Teunissen CE, Barkhof F, van Swieten JC, et al. The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease. Neurobiology of Aging. 36: 1605.e13-20. PMID 25659857 DOI: 10.1016/J.Neurobiolaging.2014.12.007  0.8
2015 Popp J, Wolfsgruber S, Heuser I, Peters O, Hüll M, Schröder J, Möller HJ, Lewczuk P, Schneider A, Jahn H, Luckhaus C, Perneczky R, Frölich L, Wagner M, Maier W, ... Wiltfang J, et al. Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type. Neurobiology of Aging. 36: 601-7. PMID 25435336 DOI: 10.1016/J.Neurobiolaging.2014.10.031  0.8
2015 Halbgebauer S, Haußmann U, Klafki H, Tumani H, Wiltfang J, Otto M. Capillary isoelectric focusing immunoassay as a new nanoscale approach for the detection of oligoclonal bands. Electrophoresis. 36: 355-62. PMID 25348366 DOI: 10.1002/Elps.201400339  0.56
2015 Oberstein TJ, Spitzer P, Klafki HW, Linning P, Neff F, Knölker HJ, Lewczuk P, Wiltfang J, Kornhuber J, Maler JM. Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides. Neurobiology of Disease. 73: 24-35. PMID 25204716 DOI: 10.1016/J.Nbd.2014.08.031  0.8
2015 Hüttenrauch M, Brauß A, Kurdakova A, Klafki H, Wiltfang J, Wirths O. Physical activity ameliorates neuron loss and memory deficits in Tg4-42 mice Pharmacopsychiatry. 25. DOI: 10.1055/S-0035-1557976  0.56
2015 Kraus I, Besong-Agbo D, Otto M, Klafki H, Wiltfang J. Measurement of ERK1/2 isoform distribution in peripheral blood mononuclear cells derived from whole blood from patients with different neuropsychiatric disorders Pharmacopsychiatry. 25. DOI: 10.1055/S-0035-1557965  0.56
2015 Esselmann H, Hafermann C, Jahn O, Kraus I, Vogelgsang J, Haußmann U, Uecker M, Liepold T, Klafki H, Wiltfang J. Analytical methods to explore Amyloid-β-Peptide variants beyond Aβ1-40 and Aβ1-42 Pharmacopsychiatry. 25. DOI: 10.1055/S-0035-1557950  0.8
2015 Bleich S, Wiltfang J, Wedekind D. Editorial/Opening Words Pharmacopsychiatry. 25. DOI: 10.1055/S-0035-1557938  0.8
2015 Peters O, Fuentes M, Joachim LK, Jessen F, Luckhaus C, Kornhuber J, Pantel J, Hüll M, Schmidtke K, Rüther E, Möller HJ, Kurz A, Wiltfang J, Maier W, Wiese B, et al. Combined treatment with memantine and galantamine-CR compared with galantamine-CR only in antidementia drug naïve patients with mild-to-moderate Alzheimer's disease Alzheimer's and Dementia: Translational Research and Clinical Interventions. 1: 198-204. DOI: 10.1016/j.trci.2015.10.001  0.8
2015 Wolfsgruber S, Polcher AA, Koppara A, Kleineidam L, Schmidtke K, Frölich L, Hampel H, Heuser I, Peters O, Jahn H, Luckhaus C, Reischies FM, Hüll M, Gertz H, Schröder J, ... ... Wiltfang J, et al. Using neuropsychological criteria to distinguish between memory clinic patients with subjective cognitive decline and MCI Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.08.102  0.8
2015 Koppara A, Wolfsgruber S, Kleineidam L, Schmidtke K, Frölich L, Kurz A, Schulz S, Hampel H, Heuser I, Peters O, Reischies FM, Jahn H, Luckhaus C, Hüll M, Gertz H, ... ... Wiltfang J, et al. The latent dementia phenotype δ is associated with the CSF Alzheimer's disease biomarker signature in subjects with mild cognitive impairment Alzheimers & Dementia. 11: 176. DOI: 10.1016/J.Jalz.2015.07.139  0.8
2015 Doorn LJCvWv, Koel-Simmelink MJ, Hausmann U, Klafki H, Struyfs H, Linning P, Knoelker H, Twaalfhoven H, Kuiperij HB, Vanmechelen E, Verbeek M, Engelborghs S, Wiltfang J, Teunissen CE. Standardization of a method for diagnostic biomarker validation for neurodegenerative diseases: App assays as example Alzheimers & Dementia. 11: 387. DOI: 10.1016/J.Jalz.2015.06.318  0.56
2014 Thelen M, Razquin C, Hernández I, Gorostidi A, Sánchez-Valle R, Ortega-Cubero S, Wolfsgruber S, Drichel D, Fliessbach K, Duenkel T, Damian M, Heilmann S, Slotosch A, Lennarz M, Seijo-Martínez M, ... ... Wiltfang J, et al. Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes. Neurobiology of Aging. 35: 2657.e13-9. PMID 25042114 DOI: 10.1016/J.Neurobiolaging.2014.06.018  0.8
2014 Ramirez A, van der Flier WM, Herold C, Ramonet D, Heilmann S, Lewczuk P, Popp J, Lacour A, Drichel D, Louwersheimer E, Kummer MP, Cruchaga C, Hoffmann P, Teunissen C, Holstege H, ... ... Wiltfang J, et al. SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease. Human Molecular Genetics. 23: 6644-58. PMID 25027320 DOI: 10.1093/Hmg/Ddu372  0.8
2014 Wolfsgruber S, Wagner M, Schmidtke K, Frölich L, Kurz A, Schulz S, Hampel H, Heuser I, Peters O, Reischies FM, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, ... ... Wiltfang J, et al. Memory concerns, memory performance and risk of dementia in patients with mild cognitive impairment. Plos One. 9: e100812. PMID 25019225 DOI: 10.1371/Journal.Pone.0100812  0.8
2014 Brauner JM, Groemer TW, Stroebel A, Grosse-Holz S, Oberstein T, Wiltfang J, Kornhuber J, Maler JM. Spot quantification in two dimensional gel electrophoresis image analysis: comparison of different approaches and presentation of a novel compound fitting algorithm. Bmc Bioinformatics. 15: 181. PMID 24915860 DOI: 10.1186/1471-2105-15-181  0.8
2014 Poschmann G, Seyfarth K, Besong Agbo D, Klafki HW, Rozman J, Wurst W, Wiltfang J, Meyer HE, Klingenspor M, Stühler K. High-fat diet induced isoform changes of the Parkinson's disease protein DJ-1. Journal of Proteome Research. 13: 2339-51. PMID 24646099 DOI: 10.1021/Pr401157K  0.56
2014 Deuschle M, Schilling C, Leweke FM, Enning F, Pollmächer T, Esselmann H, Wiltfang J, Frölich L, Heuser I. Hypocretin in cerebrospinal fluid is positively correlated with Tau and pTau. Neuroscience Letters. 561: 41-5. PMID 24373987 DOI: 10.1016/J.Neulet.2013.12.036  0.8
2014 Fritschi SK, Langer F, Kaeser SA, Maia LF, Portelius E, Pinotsi D, Kaminski CF, Winkler DT, Maetzler W, Keyvani K, Spitzer P, Wiltfang J, Kaminski Schierle GS, Zetterberg H, Staufenbiel M, et al. Highly potent soluble amyloid-β seeds in human Alzheimer brain but not cerebrospinal fluid Brain. 137: 2909-2915. DOI: 10.1093/brain/awu255  0.56
2014 Fritschi SK, Langer F, Kaeser SA, Maia LF, Maetzler W, Keyvani K, Spitzer P, Wiltfang J, Staufenbiel M, Jucker M. HIGHLY POTENT SOLUBLE Aβ SEEDS IN HUMAN ALZHEIMER BRAIN BUT NOT CEREBROSPINAL FLUID Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.1580  0.56
2013 Schrötter A, Magraoui FE, Gröttrup B, Wiltfang J, Heinsen H, Marcus K, Meyer HE, Grinberg LT, Park YM. Early diagnosis of neurodegenerative diseases - the long awaited Holy Grail and bottleneck of modern brain research - 19th HUPO BPP workshop: May 22-24, 2013, Dortmund, Germany. Proteomics. 13: 2938-41. PMID 24108682 DOI: 10.1002/Pmic.201370164  0.44
2013 Baumann R, Rabaszowski M, Stenin I, Tilgner L, Gaertner-Akerboom M, Scheckenbach K, Wiltfang J, Chaker A, Schipper J, Wagenmann M. Nasal levels of soluble IL-33R ST2 and IL-16 in allergic rhinitis: inverse correlation trends with disease severity. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 43: 1134-43. PMID 24074331 DOI: 10.1111/cea.12148  0.8
2013 Besong Agbo D, Klafki H, Poschmann G, Seyfarth K, Genius J, Janßen C, Stühler K, Wurst W, Meyer HE, Klingenspor M, Wiltfang J. Development of a capillary isoelectric focusing immunoassay to measure DJ-1 isoforms in biological samples. Analytical Biochemistry. 443: 197-204. PMID 24055619 DOI: 10.1016/J.Ab.2013.09.013  0.56
2013 Morgen K, Frölich L, Tost H, Plichta MM, Kölsch H, Rakebrandt F, Rienhoff O, Jessen F, Peters O, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, Hampel H, ... ... Wiltfang J, et al. APOE-dependent phenotypes in subjects with mild cognitive impairment converting to Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 37: 389-401. PMID 23948881 DOI: 10.3233/Jad-130326  0.8
2013 Baumann R, Rabaszowski M, Stenin I, Tilgner L, Scheckenbach K, Wiltfang J, Schipper J, Chaker A, Wagenmann M. Comparison of the nasal release of IL-4, IL-10, IL-17, CCL13/MCP-4, and CCL26/eotaxin-3 in allergic rhinitis during season and after allergen challenge. American Journal of Rhinology & Allergy. 27: 266-72. PMID 23883806 DOI: 10.2500/ajra.2013.27.3913  0.8
2013 Grabemann M, Mette C, Zimmermann M, Heinrich V, Uekermann J, Wiltfang J, Abdel-Hamid M, Zepf FD, Kis B. No clear effects of acute tryptophan depletion on processing affective prosody in male adults with ADHD Acta Psychiatrica Scandinavica. 128: 142-148. PMID 23581825 DOI: 10.1111/acps.12130  0.8
2013 Gröttrup B, Esselmann H, May C, Schrötter A, Woitalla D, Heinsen H, Marcus K, Wiltfang J, Meyer HE, Grinberg LT, Park YM. Challenges in modern biomarker discovery--17th HUPO BPP workshop: May 24-25, 2012, Sao Paulo, Brazil. Proteomics. 13: 210-6. PMID 23341064 DOI: 10.1002/Pmic.201370025  0.8
2013 Kraemer M, Herold M, Uekermann J, Kis B, Daum I, Wiltfang J, Berlit P, Diehl RR, Abdel-Hamid M. Perception of affective prosody in patients at an early stage of relapsing-remitting multiple sclerosis. Journal of Neuropsychology. 7: 91-106. PMID 23126275 DOI: 10.1111/J.1748-6653.2012.02037.X  0.8
2013 Benninghoff J, Grunze H, Schindler C, Genius J, Schloesser RJ, Van Der Ven A, Dehning S, Wiltfang J, Möller HJ, Rujescu D. Ziprasidone - Not haloperidol - Induces more de-novo neurogenesis of adult neural stem cells derived from murine hippocampus Pharmacopsychiatry. 46: 10-15. PMID 22592505 DOI: 10.1055/S-0032-1311607  0.8
2013 Christiansen H, Hirsch O, Philipsen A, Oades RD, Matthies S, Hebebrand J, Ueckermann J, Abdel-Hamid M, Kraemer M, Wiltfang J, Graf E, Colla M, Sobanski E, Alm B, Rösler M, et al. German validation of the conners adult ADHD rating scale-self-report: confirmation of factor structure in a large sample of participants with ADHD. Journal of Attention Disorders. 17: 690-8. PMID 22441889 DOI: 10.1177/1087054711435680  0.8
2013 Abdel-Hamid M, Grabemann M, Kownatka M, Zwarg T, Esselmann H, Zimmermann M, Mette C, Wiltfang J, Kis B. “The Star Trek Universe”: The change in perception of mental disease and its treatment during the last five decades Pharmacopsychiatry. 46. DOI: 10.1055/S-0033-1353358  0.8
2012 Jesse S, Lehnert S, Jahn O, Parnetti L, Soininen H, Herukka SK, Steinacker P, Tawfik S, Tumani H, von Arnim CA, Neumann M, Kretzschmar HA, Kulaksiz H, Lenter M, Wiltfang J, et al. Differential sialylation of serpin A1 in the early diagnosis of Parkinson's disease dementia. Plos One. 7: e48783. PMID 23144969 DOI: 10.1371/journal.pone.0048783  0.8
2012 Genius J, Klafki H, Benninghoff J, Esselmann H, Wiltfang J. Current application of neurochemical biomarkers in the prediction and differential diagnosis of Alzheimer's disease and other neurodegenerative dementias. European Archives of Psychiatry and Clinical Neuroscience. 262: 71-77. PMID 22986448 DOI: 10.1007/S00406-012-0362-3  0.8
2012 Bibl M, Welge V, Schmidt H, Esselmann H, Mollenhauer B, Lewczuk P, Otto M, Kornhuber J, Wiltfang J. Plasma amyloid-beta peptides in acute cerebral ischemia: a pilot study. Journal of Clinical Laboratory Analysis. 26: 238-45. PMID 22811355 DOI: 10.1002/Jcla.21511  0.8
2012 Svobodova Z, Reza Mohamadi M, Jankovicova B, Esselmann H, Verpillot R, Otto M, Taverna M, Wiltfang J, Viovy JL, Bilkova Z. Development of a magnetic immunosorbent for on-chip preconcentration of amyloid β isoforms: Representatives of Alzheimer's disease biomarkers. Biomicrofluidics. 6: 24126-2412612. PMID 22712037 DOI: 10.1063/1.4722588  0.8
2012 Bibl M, Gallus M, Welge V, Lehmann S, Sparbier K, Esselmann H, Wiltfang J. Characterization of cerebrospinal fluid aminoterminally truncated and oxidized amyloid-β peptides. Proteomics. Clinical Applications. 6: 163-9. PMID 22532452 DOI: 10.1002/prca.201100082  0.8
2012 Bibl M, Gallus M, Welge V, Esselmann H, Wolf S, Rüther E, Wiltfang J. Cerebrospinal fluid amyloid-β 2-42 is decreased in Alzheimer's, but not in frontotemporal dementia. Journal of Neural Transmission (Vienna, Austria : 1996). 119: 805-13. PMID 22527776 DOI: 10.1007/S00702-012-0801-3  0.8
2012 Koch P, Tamboli IY, Mertens J, Wunderlich P, Ladewig J, Stüber K, Esselmann H, Wiltfang J, Brüstle O, Walter J. Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation. The American Journal of Pathology. 180: 2404-16. PMID 22510327 DOI: 10.1016/J.Ajpath.2012.02.012  0.8
2012 Chávez-Gutiérrez L, Bammens L, Benilova I, Vandersteen A, Benurwar M, Borgers M, Lismont S, Zhou L, Van Cleynenbreugel S, Esselmann H, Wiltfang J, Serneels L, Karran E, Gijsen H, Schymkowitz J, et al. The mechanism of γ-Secretase dysfunction in familial Alzheimer disease. The Embo Journal. 31: 2261-74. PMID 22505025 DOI: 10.1038/emboj.2012.79  0.8
2012 Henkel AW, Müller K, Lewczuk P, Müller T, Marcus K, Kornhuber J, Wiltfang J. Multidimensional plasma protein separation technique for identification of potential Alzheimer's disease plasma biomarkers: a pilot study. Journal of Neural Transmission (Vienna, Austria : 1996). 119: 779-88. PMID 22415063 DOI: 10.1007/S00702-012-0781-3  0.8
2012 Wagner M, Wolf S, Reischies FM, Daerr M, Wolfsgruber S, Jessen F, Popp J, Maier W, Hüll M, Frölich L, Hampel H, Perneczky R, Peters O, Jahn H, Luckhaus C, ... ... Wiltfang J, et al. Biomarker validation of a cued recall memory deficit in prodromal Alzheimer disease. Neurology. 78: 379-86. PMID 22238414 DOI: 10.1212/Wnl.0B013E318245F447  0.8
2012 Raaz-Schrauder D, Klinghammer L, Baum C, Frank T, Lewczuk P, Achenbach S, Cicha I, Stumpf C, Wiltfang J, Kornhuber J, Daniel WG, Garlichs CD. Association of systemic inflammation markers with the presence and extent of coronary artery calcification. Cytokine. 57: 251-7. PMID 22172511 DOI: 10.1016/J.Cyto.2011.11.015  0.8
2012 Schrijvers EM, Schürmann B, Koudstaal PJ, van den Bussche H, Van Duijn CM, Hentschel F, Heun R, Hofman A, Jessen F, Kölsch H, Kornhuber J, Peters O, Rivadeneira F, Rüther E, Uitterlinden AG, ... ... Wiltfang J, et al. Genome-wide association study of vascular dementia. Stroke; a Journal of Cerebral Circulation. 43: 315-9. PMID 22116812 DOI: 10.1161/Strokeaha.111.628768  0.8
2012 Gerrish A, Russo G, Richards A, Moskvina V, Ivanov D, Harold D, Sims R, Abraham R, Hollingworth P, Chapman J, Hamshere M, Pahwa JS, Dowzell K, Williams A, Jones N, ... ... Wiltfang J, et al. The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 28: 377-87. PMID 22027014 DOI: 10.3233/Jad-2011-110824  0.8
2012 Christiansen H, Kis B, Hirsch O, Matthies S, Hebebrand J, Uekermann J, Abdel-Hamid M, Kraemer M, Wiltfang J, Graf E, Colla M, Sobanski E, Alm B, Rösler M, Jacob C, et al. German validation of the Conners Adult ADHD Rating Scales (CAARS) II: reliability, validity, diagnostic sensitivity and specificity. European Psychiatry : the Journal of the Association of European Psychiatrists. 27: 321-8. PMID 21392946 DOI: 10.1016/j.eurpsy.2010.12.010  0.8
2011 Spitzer P, Schieb H, Kamrowski-Kruck H, Otto M, Chiasserini D, Parnetti L, Herukka SK, Schuchhardt J, Wiltfang J, Klafki HW. Evidence for Elevated Cerebrospinal Fluid ERK1/2 Levels in Alzheimer Dementia. International Journal of Alzheimer's Disease. 2011: 739847. PMID 22145083 DOI: 10.4061/2011/739847  0.56
2011 Gröttrup B, Böckmann M, Marcus K, Wiltfang J, Grinberg LT, Meyer HE, Park YM. Clinical aspects of neurodegenerative diseases - 15th HUPO BPP Workshop April 8-9, 2011, Bochum, Germany. Proteomics. 11: 4279-83. PMID 22045679 DOI: 10.1002/Pmic.201190116  0.44
2011 Teipel SJ, Peters O, Heuser I, Jessen F, Maier W, Froelich L, Arlt S, Hüll M, Gertz HJ, Kornhuber J, Wiltfang J, Thome J, Rienhoff O, Meindl T, Hampel H, et al. Atrophy outcomes in multicentre clinical trials on Alzheimer's disease: effect of different processing and analysis approaches on sample sizes. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 12: 109-13. PMID 21906007 DOI: 10.3109/15622975.2011.603222  0.8
2011 Jessen F, Lewczuk P, Gür O, Block W, Ende G, Frölich L, Hammen T, Arlt S, Kornhuber J, Kucinski T, Popp J, Peters O, Maier W, Träber F, Wiltfang J. Association of N-acetylaspartate and cerebrospinal fluid Aβ42 in dementia. Journal of Alzheimer's Disease : Jad. 27: 393-9. PMID 21841259 DOI: 10.3233/Jad-2011-110398  0.8
2011 Schieb H, Kratzin H, Jahn O, Möbius W, Rabe S, Staufenbiel M, Wiltfang J, Klafki HW. Beta-amyloid peptide variants in brains and cerebrospinal fluid from amyloid precursor protein (APP) transgenic mice: comparison with human Alzheimer amyloid. The Journal of Biological Chemistry. 286: 33747-58. PMID 21795681 DOI: 10.1074/jbc.M111.246561  0.56
2011 Hermann DM, Keyvani K, van de Nes J, Weimar C, Wiltfang J, Nitsch RM, Szodorai A. Brain-reactive β-amyloid antibodies in primary CNS angiitis with cerebral amyloid angiopathy. Neurology. 77: 503-5. PMID 21775736 DOI: 10.1212/Wnl.0B013E318227B250  0.8
2011 Gröttrup B, Stephan C, Marcus K, Grinberg LT, Wiltfang J, Lee SK, Kim YH, Meyer HE, Park YM. Creating a human brain proteome atlas--13th HUPO BPP Workshop March 30-31, 2010, Ochang, Korea. Proteomics. 11: 2759-62. PMID 21717571 DOI: 10.1002/Pmic.201190063  0.44
2011 Urraca JL, Aureliano CS, Schillinger E, Esselmann H, Wiltfang J, Sellergren B. Polymeric complements to the Alzheimer's disease biomarker β-amyloid isoforms Aβ1-40 and Aβ1-42 for blood serum analysis under denaturing conditions. Journal of the American Chemical Society. 133: 9220-3. PMID 21630636 DOI: 10.1021/Ja202908Z  0.8
2011 Schipke CG, Jessen F, Teipel S, Luckhaus C, Wiltfang J, Esselmann H, Frölich L, Maier W, Rüther E, Heppner FL, Prokop S, Heuser I, Peters O. Long-term stability of Alzheimer's disease biomarker proteins in cerebrospinal fluid. Journal of Alzheimer's Disease : Jad. 26: 255-62. PMID 21606567 DOI: 10.3233/Jad-2011-110329  0.8
2011 Frings L, Klöppel S, Teipel S, Peters O, Frölich L, Pantel J, Schröder J, Gertz HJ, Arlt S, Heuser I, Kornhuber J, Wiltfang J, Maier W, Jessen F, Hampel H, et al. Left anterior temporal lobe sustains naming in Alzheimer's dementia and mild cognitive impairment. Current Alzheimer Research. 8: 893-901. PMID 21592050 DOI: 10.2174/156720511798192673  0.8
2011 Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, ... ... Wiltfang J, et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nature Genetics. 43: 429-35. PMID 21460840 DOI: 10.1038/Ng.803  0.8
2011 Verpillot R, Esselmann H, Mohamadi MR, Klafki H, Poirier F, Lehnert S, Otto M, Wiltfang J, Jean-Louis V, Taverna M. Analysis of amyloid-β peptides in cerebrospinal fluid samples by capillary electrophoresis coupled with LIF detection. Analytical Chemistry. 83: 1696-703. PMID 21314132 DOI: 10.1021/ac102828f  0.8
2011 Mollenhauer B, Esselmann H, Trenkwalder C, Schulz-Schaeffer W, Kretzschmar H, Otto M, Wiltfang J, Bibl M. CSF amyloid-β peptides in neuropathologically diagnosed dementia with Lewy bodies and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 24: 383-91. PMID 21297274 DOI: 10.3233/JAD-2011-101551  0.8
2011 Mollenhauer B, Esselmann H, Roeber S, Schulz-Schaeffer WJ, Trenkwalder C, Bibl M, Steinacker P, Kretzschmar HA, Wiltfang J, Otto M. Different CSF β-amyloid processing in Alzheimer's and Creutzfeldt-Jakob disease. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 691-7. PMID 21210287 DOI: 10.1007/s00702-010-0543-z  0.8
2011 Bibl M, Mollenhauer B, Lewczuk P, Esselmann H, Wolf S, Otto M, Kornhuber J, Rüther E, Wiltfang J. Cerebrospinal fluid tau, p-tau 181 and amyloid-β38/40/42 in frontotemporal dementias and primary progressive aphasias. Dementia and Geriatric Cognitive Disorders. 31: 37-44. PMID 21135556 DOI: 10.1159/000322370  0.8
2011 Ott S, Henkel AW, Henkel MK, Redzic ZB, Kornhuber J, Wiltfang J. Pre-aggregated Aβ1-42 peptide increases tau aggregation and hyperphosphorylation after short-term application. Molecular and Cellular Biochemistry. 349: 169-77. PMID 21113648 DOI: 10.1007/S11010-010-0671-7  0.8
2011 Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, ... ... Wiltfang J, et al. Correction: Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease Plos One. 6. DOI: 10.1371/annotation/a0bb886d-d345-4a20-a82e-adce9b047798  0.8
2010 Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, ... ... Wiltfang J, et al. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. Plos One. 5: e13950. PMID 21085570 DOI: 10.1371/Journal.Pone.0013950  0.8
2010 Vieira SI, Rebelo S, Esselmann H, Wiltfang J, Lah J, Lane R, Small SA, Gandy S, da Cruz E Silva EF, da Cruz E Silva OA. Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated. Molecular Neurodegeneration. 5: 40. PMID 20937087 DOI: 10.1186/1750-1326-5-40  0.8
2010 Spitzer P, Herrmann M, Klafki HW, Smirnov A, Lewczuk P, Kornhuber J, Wiltfang J, Maler JM. Phagocytosis and LPS alter the maturation state of β-amyloid precursor protein and induce different Aβ peptide release signatures in human mononuclear phagocytes. Journal of Neuroinflammation. 7: 59. PMID 20929546 DOI: 10.1186/1742-2094-7-59  0.8
2010 Spitzer P, Klafki HW, Blennow K, Buée L, Esselmann H, Herruka SK, Jimenez C, Klivenyi P, Lewczuk P, Maler JM, Markus K, Meyer HE, Morris C, Müller T, Otto M, ... ... Wiltfang J, et al. cNEUPRO: Novel Biomarkers for Neurodegenerative Diseases. International Journal of Alzheimer's Disease. 2010. PMID 20886057 DOI: 10.4061/2010/548145  0.8
2010 Bibl M, Esselmann H, Lewczuk P, Trenkwalder C, Otto M, Kornhuber J, Wiltfang J, Mollenhauer B. Combined Analysis of CSF Tau, Aβ42, Aβ1-42% and Aβ1-40% in Alzheimer's Disease, Dementia with Lewy Bodies and Parkinson's Disease Dementia. International Journal of Alzheimer's Disease. 2010. PMID 20862375 DOI: 10.4061/2010/761571  0.8
2010 Steinacker P, Klafki H, Lehnert S, Jesse S, Arnim CA, Tumani H, Pabst A, Kretzschmar HA, Wiltfang J, Otto M. ERK2 is increased in cerebrospinal fluid of Creutzfeldt-Jakob disease patients. Journal of Alzheimer's Disease : Jad. 22: 119-28. PMID 20847405 DOI: 10.3233/JAD-2010-100030  0.8
2010 Mohamadi MR, Svobodova Z, Verpillot R, Esselmann H, Wiltfang J, Otto M, Taverna M, Bilkova Z, Viovy JL. Microchip electrophoresis profiling of Aβ peptides in the cerebrospinal fluid of patients with Alzheimer's disease. Analytical Chemistry. 82: 7611-7. PMID 20722394 DOI: 10.1021/Ac101337N  0.8
2010 Schmidt D, Zimmermann R, Lewczuk P, Schaller G, Degirmenci U, Kreil S, Wiltfang J, Kuwert T, Kornhuber J, Weih M. Confirmation rate of blinded (99m)Tc-SPECT compared to neurochemical dementia biomarkers in CSF in patients with Alzheimer disease. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 1111-4. PMID 20694486 DOI: 10.1007/S00702-010-0459-7  0.8
2010 Alexopoulos P, Kurz A, Lewczuk P, Kornhuber J, Wiltfang J, Maier W, Förstl H, Perneczky R. The sortilin-related receptor SORL1 and the amyloid cascade: a possible explanation for the concurrent elevation of CSF soluble APPalpha and APPbeta in Alzheimer's disease. International Journal of Geriatric Psychiatry. 25: 542-3. PMID 20391590 DOI: 10.1002/Gps.2349  0.8
2010 Zimmermann R, Beck G, Knispel S, Maler JM, Weih M, Wiltfang J, Kornhuber J, Lewczuk P. Intrathecal IgG synthesis in patients with alterations in the neurochemical dementia diagnostics. Journal of Alzheimer's Disease. 19: 1199-1203. PMID 20308786 DOI: 10.3233/Jad-2010-1313  0.8
2010 Steinacker P, Rist W, Swiatek-de-Lange M, Lehnert S, Jesse S, Pabst A, Tumani H, von Arnim CA, Mitrova E, Kretzschmar HA, Lenter M, Wiltfang J, Otto M. Ubiquitin as potential cerebrospinal fluid marker of Creutzfeldt-Jakob disease. Proteomics. 10: 81-9. PMID 19882659 DOI: 10.1002/pmic.200900246  0.8
2010 Ebert S, Goos M, Rollwagen L, Baake D, Zech WD, Esselmann H, Wiltfang J, Mollenhauer B, Schliebs R, Gerber J, Nau R. Recurrent systemic infections with Streptococcus pneumoniae do not aggravate the course of experimental neurodegenerative diseases. Journal of Neuroscience Research. 88: 1124-36. PMID 19859962 DOI: 10.1002/jnr.22270  0.8
2010 Lewczuk P, Kornhuber J, Vanmechelen E, Peters O, Heuser I, Maier W, Jessen F, Bürger K, Hampel H, Frölich L, Henn F, Falkai P, Rüther E, Jahn H, Luckhaus Ch, ... ... Wiltfang J, et al. Amyloid beta peptides in plasma in early diagnosis of Alzheimer's disease: A multicenter study with multiplexing. Experimental Neurology. 223: 366-70. PMID 19664622 DOI: 10.1016/J.Expneurol.2009.07.024  0.8
2010 Lewczuk P, Kamrowski-Kruck H, Peters O, Heuser I, Jessen F, Popp J, Bürger K, Hampel H, Frölich L, Wolf S, Prinz B, Jahn H, Luckhaus Ch, Perneczky R, Hüll M, ... ... Wiltfang J, et al. Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study. Molecular Psychiatry. 15: 138-45. PMID 18663368 DOI: 10.1038/Mp.2008.84  0.8
2009 Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, ... ... Wiltfang J, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nature Genetics. 41: 1088-93. PMID 19734902 DOI: 10.1038/Ng.440  0.8
2009 Lewczuk P, Zimmermann R, Wiltfang J, Kornhuber J. Neurochemical dementia diagnostics: a simple algorithm for interpretation of the CSF biomarkers Journal of Neural Transmission. 116: 1163-1167. PMID 19653063 DOI: 10.1007/S00702-009-0277-Y  0.8
2009 Klafki HW, Lewczuk P, Kamrowski-Kruck H, Maler JM, Müller K, Peters O, Heuser I, Jessen F, Popp J, Frölich L, Wolf S, Prinz B, Luckhaus C, Schröder J, Pantel J, ... ... Wiltfang J, et al. Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form. Journal of Alzheimer's Disease : Jad. 18: 613-22. PMID 19625747 DOI: 10.3233/Jad-2009-1167  0.8
2009 Linka T, Sartory G, Wiltfang J, Müller BW. Treatment effects of serotonergic and noradrenergic antidepressants on the intensity dependence of auditory ERP components in major depression. Neuroscience Letters. 463: 26-30. PMID 19616062 DOI: 10.1016/j.neulet.2009.07.038  0.8
2009 Weih M, Krinninger M, Zimmermann R, Lewczuk P, Svitek J, Schaller G, Degirmenci Ü, Richter-Schmidinger T, Wiltfang J, Kuwert T, Kornhuber J, Schmidt D. [Sensitivity of neurochemical dementia diagnostics in CSF compared to 99mTc-SPECT in Alzheimer's dementia]. Fortschritte Der Neurologie Psychiatrie. 77: 407-411. PMID 19582652 DOI: 10.1055/S-0028-1109493  0.8
2009 Verwey NA, Veerhuis R, Twaalfhoven HA, Wouters D, Hoozemans JJ, Bollen YJ, Killestein J, Bibl M, Wiltfang J, Hack CE, Scheltens P, Blankenstein MA. Quantification of amyloid-beta 40 in cerebrospinal fluid. Journal of Immunological Methods. 348: 57-66. PMID 19576899 DOI: 10.1016/J.Jim.2009.06.011  0.8
2009 Alexopoulos P, Günther F, Popp J, Jessen F, Peters O, Wolf S, Kneib T, Kurz A, Richter-Schmidinger T, Lewczuk P, Bleich S, Wiltfang J, Kornhuber J. Plasma homocysteine and cerebrospinal fluid neurodegeneration biomarkers in mild cognitive impairment and dementia. Journal of the American Geriatrics Society. 57: 737-9. PMID 19405180 DOI: 10.1111/J.1532-5415.2009.02212.X  0.8
2009 Kölsch H, Jessen F, Wiltfang J, Lewczuk P, Dichgans M, Teipel SJ, Kornhuber J, Frölich L, Heuser I, Peters O, Wiese B, Kaduszkiewicz H, van den Bussche H, Hüll M, Kurz A, et al. Association of SORL1 gene variants with Alzheimer's disease. Brain Research. 1264: 1-6. PMID 19368828 DOI: 10.1016/J.Brainres.2009.01.044  0.8
2009 Verwey NA, van der Flier WM, Blennow K, Clark C, Sokolow S, De Deyn PP, Galasko D, Hampel H, Hartmann T, Kapaki E, Lannfelt L, Mehta PD, Parnetti L, Petzold A, Pirttila T, ... ... Wiltfang J, et al. A worldwide multicentre comparison of assays for cerebrospinal fluid biomarkers in Alzheimer's disease. Annals of Clinical Biochemistry. 46: 235-40. PMID 19342441 DOI: 10.1258/Acb.2009.008232  0.8
2009 Kornhuber J, Schmidtke K, Frolich L, Perneczky R, Wolf S, Hampel H, Jessen F, Heuser I, Peters O, Weih M, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J, ... ... Wiltfang J, et al. Early and differential diagnosis of dementia and mild cognitive impairment: design and cohort baseline characteristics of the German Dementia Competence Network. Dementia and Geriatric Cognitive Disorders. 27: 404-17. PMID 19339779 DOI: 10.1159/000210388  0.8
2009 Serneels L, Van Biervliet J, Craessaerts K, Dejaegere T, Horré K, Van Houtvin T, Esselmann H, Paul S, Schäfer MK, Berezovska O, Hyman BT, Sprangers B, Sciot R, Moons L, Jucker M, ... ... Wiltfang J, et al. gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease. Science (New York, N.Y.). 324: 639-42. PMID 19299585 DOI: 10.1126/Science.1171176  0.8
2009 Weih M, Abu-Omar K, Esselmann H, Gelbrich G, Lewczuk P, Rütten A, Wiltfang J, Kornhuber J. Physical activity and prevention of Alzheimer's dementia: current evidence and feasibility of an interventional trial Fortschritte Der Neurologie-Psychiatrie. 77: 146-151. PMID 19283649 DOI: 10.1055/S-0028-1109068  0.8
2009 Blennow K, De Meyer G, Hansson O, Minthon L, Wallin A, Zetterberg H, Lewczuk P, Vanderstichele H, Vanmechelen E, Kornhuber J, Wiltfang J, Heuser I, Maier W, Luckhaus C, et al. Evolution of Abeta42 and Abeta40 levels and Abeta42/Abeta40 ratio in plasma during progression of Alzheimer's disease: a multicenter assessment. The Journal of Nutrition, Health & Aging. 13: 205-8. PMID 19262954 DOI: 10.1007/S12603-009-0059-0  0.8
2009 Kornhuber J, Terfloth L, Bleich S, Wiltfang J, Rupprecht R. Molecular properties of psychopharmacological drugs determining non-competitive inhibition of 5-HT3A receptors European Journal of Medicinal Chemistry. 44: 2667-2672. PMID 19144451 DOI: 10.1016/J.Ejmech.2008.12.003  0.8
2009 Welge V, Fiege O, Lewczuk P, Mollenhauer B, Esselmann H, Klafki H, Wolf S, Trenkwalder C, Otto M, Kornhuber J, Wiltfang J, Bibl M. Combined CSF tau, p-tau181 and amyloid-β 38/40/42 for diagnosing Alzheimer’s disease Journal of Neural Transmission. 116: 203-212. PMID 19142572 DOI: 10.1007/S00702-008-0177-6  0.8
2009 Maler JM, Spitzer P, Klafki H, Esselmann H, Lewczuk P, Kornhuber J, Herrmann M, Wiltfang J. Distinct fractional Aβ release patterns in human mononuclear phagocytes Journal of Neuroimmunology. 206: 1-4. PMID 18824266 DOI: 10.1016/J.Jneuroim.2008.08.010  0.8
2009 Leuchtenberger S, Maler J, Czirr E, Ness J, Lichtenthaler SF, Esselmann H, Pietrzik CU, Wiltfang J, Weggen S. Nonsteroidal anti-inflammatory drugs and ectodomain shedding of the amyloid precursor protein. Neuro-Degenerative Diseases. 6: 1-8. PMID 18349521 DOI: 10.1159/000121391  0.8
2009 Smirnov A, Trupp A, Henkel AW, Bloch E, Reulbach U, Lewczuk P, Riggert J, Kornhuber J, Wiltfang J. Differential processing and secretion of Abeta peptides and sAPPalpha in human platelets is regulated by thrombin and prostaglandine 2. Neurobiology of Aging. 30: 1552-62. PMID 18255193 DOI: 10.1016/J.Neurobiolaging.2007.12.009  0.8
2009 Wiltfang J, Lewczuk P, Riederer P, Grünblatt E, Hock C, Scheltens P, Hampel H, Vanderstichele H, Iqbal K, Galasko D, Lannfelt L, Otto M, Esselman H, Henkel AW, Kornhuber J, et al. Consensus paper of the WFSBP task force on biological markers of dementia: The role of CSF and blood analysis in the early and differential diagnosis of dementia | Trabalho de consenso de força-tarefa da WFSBP sobre marcadores biológicos das demências: Contribuição da análise do LCR e do sangue para o diagnóstico precoce e diferencial das demências Revista De Psiquiatria Clinica. 36: 1-16. DOI: 10.1590/S0101-60832009000700001  0.8
2009 Hofmann A, Welge V, Fiege O, Lewczuk P, Wolf S, Mollenhauer B, Wiltfang J, Bibl M. CSF Tau, phospho-Tau181 and amyloid-β 38/40/42 in frontotemporal dementia and pimary progressive aphasia Aktuelle Neurologie. 36. DOI: 10.1055/S-0029-1238452  0.8
2009 Maler J, Klafki H, Spitzer P, Esselmann H, Lewczuk P, Kornhuber J, Wiltfang J. Nachweis komplexer Aβ-Peptidmuster in humanem Plasma Aktuelle Neurologie. 36. DOI: 10.1055/S-0029-1238337  0.8
2009 Jessen F, Träber F, Block W, Gür O, Frölich L, Ende G, Hammen T, Kucinski T, Jahn H, Kornhuber J, Lewczuk P, Wiltfang J. Correlation of CSF biomarkers with 1H-MRS metabolites of the medial temporal lobe in Alzheimer's Disease Alzheimers & Dementia. 5: 126. DOI: 10.1016/J.Jalz.2009.05.425  0.8
2009 Lewczuk P, Zimmermann R, Wiltfang J, Kornhuber J. CSF biomarkers of Alzheimer's disease: An algorithm for interpretation of neurochemical dementia diagnostics analysis Alzheimers & Dementia. 5: 347. DOI: 10.1016/J.Jalz.2009.04.1200  0.8
2009 Kim YH, Marcus K, Grinberg LT, Goehler H, Wiltfang J, Stephan C, Eisenacher M, Hardt T, Martens L, Dunn MJ, Park YM, Meyer HE. Toward a successful clinical neuroproteomics: The 11th HUPO Brain Proteome Project workshop 3 March 2009, Kolymbari, Greece Proteomics - Clinical Applications. 3: 1012-1016. DOI: 10.1002/prca.200900100  0.8
2008 Lewczuk P, Hornegger J, Zimmermann R, Otto M, Wiltfang J, Kornhuber J. Neurochemical dementia diagnostics: assays in CSF and blood. European Archives of Psychiatry and Clinical Neuroscience. 258: 44-49. PMID 18985294 DOI: 10.1007/S00406-008-5005-3  0.8
2008 Kessler H, Pajonk FG, Bach D, Schneider-Axmann T, Falkai P, Herrmann W, Multhaup G, Wiltfang J, Schäfer S, Wirths O, Bayer TA. Effect of copper intake on CSF parameters in patients with mild Alzheimer's disease: a pilot phase 2 clinical trial. Journal of Neural Transmission (Vienna, Austria : 1996). 115: 1651-9. PMID 18972062 DOI: 10.1007/s00702-008-0136-2  0.8
2008 Brechlin P, Jahn O, Steinacker P, Cepek L, Kratzin H, Lehnert S, Jesse S, Mollenhauer B, Kretzschmar HA, Wiltfang J, Otto M. Cerebrospinal fluid-optimized two-dimensional difference gel electrophoresis (2-D DIGE) facilitates the differential diagnosis of Creutzfeldt-Jakob disease. Proteomics. 8: 4357-66. PMID 18814332 DOI: 10.1002/pmic.200800375  0.8
2008 Mamo JCL, Jian l, James AP, Flicker L, Esselmann H, Wiltfang J. Plasma lipoprotein β-amyloid in subjects with Alzheimer's disease or mild cognitive impairment: Annals of Clinical Biochemistry. 45: 395-403. PMID 18583625 DOI: 10.1258/Acb.2008.007214  0.8
2008 Kölsch H, Jessen F, Wiltfang J, Lewczuk P, Dichgans M, Kornhuber J, Frölich L, Heuser I, Peters O, Schulz JB, Schwab SG, Maier W. Influence of SORL1 gene variants: association with CSF amyloid-beta products in probable Alzheimer's disease. Neuroscience Letters. 440: 68-71. PMID 18541377 DOI: 10.1016/J.Neulet.2008.05.049  0.8
2008 Maler JM, Spitzer P, Klafki H, Esselmann H, Bibl M, Lewczuk P, Kornhuber J, Herrmann M, Wiltfang J. Adherence-dependent shifts in the patterns of β-amyloid peptides secreted by human mononuclear phagocytes Brain Behavior and Immunity. 22: 1044-1048. PMID 18511234 DOI: 10.1016/J.Bbi.2008.04.003  0.8
2008 Hamacher M, Eisenacher M, Tribl F, Stephan C, Marcus K, Hardt T, Wiltfang J, Martens L, Desiderio D, Gutstein H, Young MP, Meyer HE. The HUPO brain proteome project wish list - Summary of the 9th HUPO BPP workshop: 9-10 January 2008, Barbados Proteomics. 8: 2160-2164. PMID 18452233 DOI: 10.1002/Pmic.200800090  0.8
2008 Czirr E, Cottrell BA, Leuchtenberger S, Kukar T, Ladd TB, Esselmann H, Paul S, Schubenel R, Torpey JW, Pietrzik CU, Golde TE, Wiltfang J, Baumann K, Koo EH, Weggen S. Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretase. The Journal of Biological Chemistry. 283: 17049-54. PMID 18426795 DOI: 10.1074/Jbc.M802912200  0.8
2008 Hamacher M, Stephan C, Hardt T, Eisenacher M, Henkel A, Wiltfang J, Jimenez CR, Park YM, Marcus K, Meyer HE. Applications in brain proteomics: 8(th) HUPO Brain Proteome Project Workshop 7 October 2007, Seoul, Korea. Proteomics. 8: 1750-3. PMID 18384107 DOI: 10.1002/pmic.200701120  0.44
2008 Henkel AW, Sperling W, Rotter A, Reulbach U, Reichardt C, Bönsch D, Maler JM, Kornhuber J, Wiltfang J. Antidepressant drugs modulate growth factors in cultured cells. Bmc Pharmacology. 8: 6. PMID 18318898 DOI: 10.1186/1471-2210-8-6  0.8
2008 Hoglund K, Hansson O, Buchhave P, Zetterberg H, Lewczuk P, Londos E, Blennow K, Minthon L, Wiltfang J. Prediction of Alzheimer's disease using a cerebrospinal fluid pattern of C-terminally truncated beta-amyloid peptides Neurodegenerative Diseases. 5: 268-276. PMID 18309230 DOI: 10.1159/000119457  0.8
2008 Lewczuk P, Wiltfang J. Neurochemical dementia diagnostics: State of the art and research perspectives. Proteomics. 8: 1292-301. PMID 18271068 DOI: 10.1002/pmic.200700703  0.32
2008 Bibl M, Mollenhauer B, Esselmann H, Schneider M, Lewczuk P, Welge V, Gross M, Falkai P, Kornhuber J, Wiltfang J. Cerebrospinal fluid neurochemical phenotypes in vascular dementias: original data and mini-review. Dementia and Geriatric Cognitive Disorders. 25: 256-265. PMID 18270488 DOI: 10.1159/000115975  0.8
2008 Svitek J, Heberlein A, Bleich S, Wiltfang J, Kornhuber J, Hillemacher T. Extensive craving in high dose zolpidem dependency. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 32: 591-592. PMID 18068286 DOI: 10.1016/J.Pnpbp.2007.11.001  0.8
2008 Kornhuber J, Tripal P, Reichel M, Terfloth L, Bleich S, Wiltfang J, Gulbins E. Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of Medicinal Chemistry. 51: 219-37. PMID 18027916 DOI: 10.1021/Jm070524A  0.8
2008 Lewczuk P, Kornhuber J, Vanderstichele H, Vanmechelen E, Esselmann H, Bibl M, Wolf S, Otto M, Reulbach U, Kölsch H, Jessen F, Schröder J, Schönknecht P, Hampel H, Peters O, ... ... Wiltfang J, et al. Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study. Neurobiology of Aging. 29: 812-8. PMID 17239996 DOI: 10.1016/J.Neurobiolaging.2006.12.010  0.8
2008 Alexopoulos P, Guenther F, Schmidinger TR, Gruss B, Wiltfang J, Bleich S, Kornhuber J. Plasma homocystein levels in relation to β Amyloid and Tau Protein in cerebrospinal fluid of patients with Mild Cognitive Impairment and Alzheimer's Disease Annals of General Psychiatry. 7: 1-1. DOI: 10.1186/1744-859X-7-S1-S185  0.8
2008 Gabelle A, Roche S, Gény C, Portet F, Touchon J, Lehmann S, Meyer GD, Shapiro F, Vanderstichele H, Vanmechelen E, Engelborghs S, Deyn PPD, Shaw L, Trojanowski J, Nestor SM, ... ... Wiltfang J, et al. 1st Conference Clinical Trials on Alzheimer’s Disease September 17-18-19, 2008 School of Medecine Montpellier, France Journal of Nutrition Health & Aging. 12: 531-543. DOI: 10.1007/Bf02983205  0.8
2007 Waltereit R, Schulte-Brochterbeck G, Wiltfang J, Frölich L. AIDS dementia complex and Hashimoto encephalopathy in a senescent woman. International Journal of Geriatric Psychiatry. 22: 1267-8. PMID 18033678 DOI: 10.1002/Gps.1820  0.8
2007 Maler JM, Klafki HW, Paul S, Spitzer P, Groemer TW, Henkel AW, Esselmann H, Lewczuk P, Kornhuber J, Wiltfang J. Urea-based two-dimensional electrophoresis of beta-amyloid peptides in human plasma: evidence for novel Abeta species. Proteomics. 7: 3815-20. PMID 17924594 DOI: 10.1002/Pmic.200700311  0.8
2007 Englund H, Annerén G, Gustafsson J, Wester U, Wiltfang J, Lannfelt L, Blennow K, Höglund K. Increase in beta-amyloid levels in cerebrospinal fluid of children with Down syndrome. Dementia and Geriatric Cognitive Disorders. 24: 369-74. PMID 17914261 DOI: 10.1159/000109215  0.8
2007 Rebelo S, Vieira SI, Esselmann H, Wiltfang J, da Cruz e Silva EF, da Cruz e Silva OA. Tyr687 dependent APP endocytosis and Abeta production. Journal of Molecular Neuroscience : Mn. 32: 1-8. PMID 17873282 DOI: 10.1007/S12031-007-0001-Z  0.8
2007 Mollenhauer B, Steinacker P, Bahn E, Bibl M, Brechlin P, Schlossmacher MG, Locascio JJ, Wiltfang J, Kretzschmar HA, Poser S, Trenkwalder C, Otto M. Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: marker candidates for dementia with Lewy bodies. Neuro-Degenerative Diseases. 4: 366-75. PMID 17622779 DOI: 10.1159/000105157  0.8
2007 Hamacher M, Stephan C, Eisenacher M, Lewczuk P, Wiltfang J, Martens L, Vizcaíno JA, Kwon KH, Yoo JS, Park YM, Beckers J, Horsch M, de Angelis MH, Cho ZH, Apweiler R, et al. High Performance Proteomics: 7th HUPO Brain Proteome Project Workshop March 7-9, 2007 Wellcome Trust Conference Centre, Hinxton, UK. Proteomics. 7: 2490-6. PMID 17610211 DOI: 10.1002/Pmic.200700449  0.8
2007 Rebelo S, Vieira SI, Esselmann H, Wiltfang J, da Cruz e Silva EF, da Cruz e Silva OA. Tyrosine 687 phosphorylated Alzheimer's amyloid precursor protein is retained intracellularly and exhibits a decreased turnover rate. Neuro-Degenerative Diseases. 4: 78-87. PMID 17596701 DOI: 10.1159/000101831  0.8
2007 Kornhuber J, Kennepohl EM, Bleich S, Wiltfang J, Kraus T, Reulbach U, Meineke I. Memantine pharmacotherapy: a naturalistic study using a population pharmacokinetic approach. Clinical Pharmacokinectics. 46: 599-612. PMID 17596105 DOI: 10.2165/00003088-200746070-00005  0.8
2007 Weih M, Wiltfang J, Kornhuber J. Non-pharmacologic prevention of Alzheimer's disease: nutritional and life-style risk factors. Journal of Neural Transmission. 114: 1187-1197. PMID 17557131 DOI: 10.1007/S00702-007-0704-X  0.8
2007 Popp J, Thal DR, Lewczuk P, Wiltfang J, Jessen F. Histologically confirmed amyloid deposition and low CSF Aβ42 in a cognitively normal subject Journal of Neurology. 254: 970-971. PMID 17361344 DOI: 10.1007/S00415-006-0445-Z  0.8
2007 Bibl M, Mollenhauer B, Lewczuk P, Esselmann H, Wolf S, Trenkwalder C, Otto M, Stiens G, Rüther E, Kornhuber J, Wiltfang J. Validation of amyloid-beta peptides in CSF diagnosis of neurodegenerative dementias. Molecular Psychiatry. 12: 671-680. PMID 17339876 DOI: 10.1038/Sj.Mp.4001967  0.8
2007 Sperling W, Kornhuber J, Wiltfang J, Bleich S. Combined VNS-rTMS treatment in a patient with therapy resistant depression. Pharmacopsychiatry. 40: 39-40. PMID 17327961 DOI: 10.1055/S-2006-958524  0.8
2007 Mollenhauer B, Bibl M, Esselmann H, Steinacker P, Trenkwalder C, Wiltfang J, Otto M. Tauopathies and synucleinopathies: Do cerebrospinal fluid β-amyloid peptides reflect disease-specific pathogenesis? Journal of Neural Transmission. 114: 919-927. PMID 17318305 DOI: 10.1007/S00702-007-0629-4  0.8
2007 Bibl M, Esselmann H, Mollenhauer B, Wiltfang J. Aminoterminally truncated and oxidized amyloid-beta peptide species in Alzheimer's disease. Neuroscience. 146: 17-18. PMID 17317020 DOI: 10.1016/J.Neuroscience.2007.01.010  0.8
2007 Henkel AW, Dittrich PS, Groemer TW, Lemke EA, Klingauf J, Klafki HW, Lewczuk P, Esselmann H, Schwille P, Kornhuber J, Wiltfang J. Immune complexes of auto-antibodies against Aβ1-42 peptides patrol cerebrospinal fluid of non-Alzheimer's patients Molecular Psychiatry. 12: 601-610. PMID 17279093 DOI: 10.1038/Sj.Mp.4001947  0.8
2007 Wiltfang J, Esselmann H, Bibl M, Hüll M, Hampel H, Kessler H, Frölich L, Schröder J, Peters O, Jessen F, Luckhaus C, Perneczky R, Jahn H, Fiszer M, Maler JM, et al. Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load. Journal of Neurochemistry. 101: 1053-9. PMID 17254013 DOI: 10.1111/J.1471-4159.2006.04404.X  0.8
2007 Bibl M, Mollenhauer B, Wolf S, Esselmann H, Lewczuk P, Kornhuber J, Wiltfang J. Reduced CSF carboxyterminally truncated Aβ peptides in frontotemporal lobe degenerations Journal of Neural Transmission. 114: 621-628. PMID 17245538 DOI: 10.1007/S00702-006-0618-Z  0.8
2007 Lehrl S, Gerstmeyer K, Jacob JH, Frieling H, Henkel AW, Meyrer R, Wiltfang J, Kornhuber J, Bleich S. Blue light improves cognitive performance Journal of Neural Transmission. 114: 457-460. PMID 17245536 DOI: 10.1007/S00702-006-0621-4  0.8
2007 Maihöfner C, Sperling W, Kaltenhäuser M, Bleich S, de Zwaan M, Wiltfang J, Thürauf N, Elstner S, Reulbach U, Lewczuk P, Kornhuber J, Ropohl A. Spontaneous magnetoencephalographic activity in patients with obsessive-compulsive disorder Brain Research. 1129: 200-205. PMID 17156764 DOI: 10.1016/J.Brainres.2006.10.048  0.8
2007 Cepek L, Brechlin P, Steinacker P, Mollenhauer B, Klingebiel E, Bibl M, Kretzschmar HA, Wiltfang J, Otto M. Proteomic analysis of the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Dementia and Geriatric Cognitive Disorders. 23: 22-8. PMID 17068393 DOI: 10.1159/000096589  0.8
2007 Thuerauf N, Lunkenheimer J, Lunkenheimer B, Sperling W, Bleich S, Schlabeck M, Wiltfang J, Kornhuber J. Memantine fails to facilitate partial cigarette deprivation in smokers--no role of Memantine in the treatment of nicotine dependency? Journal of Neural Transmission. 114: 351-357. PMID 17043926 DOI: 10.1007/S00702-006-0570-Y  0.8
2007 Maler J, Spitzer P, Lewczuk P, Kornhuber J, Herrmann M, Wiltfang J. Decreases of hematopoietic stem cells in early Alzheimer's disease Pharmacopsychiatry. 40. DOI: 10.1055/S-2007-991811  0.8
2007 Klafki H, Paul S, Esselmann H, Leuthäusser S, Staufenbiel M, Wiltfang J. A-beta peptide signatures in brains, CSF and blood plasma from APP23 transgenic mice Pharmacopsychiatry. 40. DOI: 10.1055/S-2007-991810  0.8
2007 Wiltfang J, Bibl M, Maler M, Klafki H-, Esselmann H, Kornhuber J, Lewczuk P. Neurochemische Demenzdiagnostik – Quo vadis? Nervenheilkunde. 26: 861-866. DOI: 10.1055/S-0038-1626937  0.8
2007 Wiltfang J, Bibl M, Maler M, Klafki H-, Esselmann H, Kornhuber J, Lewczuk P. Neurochemische Frühdiagnostik und klinische Neuroproteomik demenzieller Erkrankungen Nervenheilkunde. 26: 853-860. DOI: 10.1055/S-0038-1626936  0.8
2006 Lewczuk P, Beck G, Ganslandt O, Esselmann H, Deisenhammer F, Regeniter A, Petereit HF, Tumani H, Gerritzen A, Oschmann P, Schröder J, Schönknecht P, Zimmermann K, Hampel H, Bürger K, ... ... Wiltfang J, et al. International quality control survey of neurochemical dementia diagnostics. Neuroscience Letters. 409: 1-4. PMID 17045397 DOI: 10.1016/J.Neulet.2006.07.009  0.8
2006 Kornhuber J, Riederer P, Bleich S, Wiltfang J, Kraus T, Meineke I. Pharmacokinetic characterization of amantadine in human brain tissue. Therapeutic Drug Monitoring. 28: 693-695. PMID 17038888 DOI: 10.1097/01.Ftd.0000245390.48552.04  0.8
2006 Maler JM, Spitzer P, Lewczuk P, Kornhuber J, Herrmann M, Wiltfang J. Decreased circulating CD34+ stem cells in early Alzheimer's disease: Evidence for a deficient hematopoietic brain support? Molecular Psychiatry. 11: 1113-1115. PMID 17033629 DOI: 10.1038/Sj.Mp.4001913  0.8
2006 Klafki H, Staufenbiel M, Kornhuber J, Wiltfang J. Therapeutic approaches to Alzheimer's disease. Brain. 129: 2840-2855. PMID 17018549 DOI: 10.1093/Brain/Awl280  0.8
2006 Hamacher M, Apweiler R, Arnold G, Becker A, Blüggel M, Carrette O, Colvis C, Dunn MJ, Fröhlich T, Fountoulakis M, van Hall A, Herberg F, Ji J, Ji J, Kretzschmar H, ... ... Wiltfang J, et al. HUPO Brain Proteome Project: summary of the pilot phase and introduction of a comprehensive data reprocessing strategy. Proteomics. 6: 4890-8. PMID 16927433 DOI: 10.1002/Pmic.200600295  0.8
2006 Bibl M, Mollenhauer B, Esselmann H, Lewczuk P, Trenkwalder C, Brechlin P, Rüther E, Kornhuber J, Otto M, Wiltfang J. CSF diagnosis of Alzheimer’s disease and dementia with Lewy bodies Journal of Neural Transmission. 113: 1771-1778. PMID 16906356 DOI: 10.1007/S00702-006-0537-Z  0.8
2006 Mollenhauer B, Trenkwalder C, Von Ahsen N, Bibl M, Steinacker P, Brechlin P, Schindehuette J, Poser S, Wiltfang J, Otto M. Beta-amlyoid 1-42 and tau-protein in cerebrospinal fluid of patients with Parkinson's disease dementia Dementia and Geriatric Cognitive Disorders. 22: 200-208. PMID 16899997 DOI: 10.1159/000094871  0.8
2006 Lewczuk P, Kornhuber J, Wiltfang J. The German Competence Net Dementias: Standard operating procedures for the neurochemical dementia diagnostics Journal of Neural Transmission. 113: 1075-1080. PMID 16835693 DOI: 10.1007/S00702-006-0511-9  0.8
2006 Kornhuber J, Wiltfang J, Riederer P, Bleich S. Neuroleptic drugs in the human brain: clinical impact of persistence and region-specific distribution. European Archives of Psychiatry and Clinical Neuroscience. 256: 274-280. PMID 16788768 DOI: 10.1007/S00406-006-0661-7  0.8
2006 Bibl M, Mollenhauer B, Esselmann H, Lewczuk P, Klafki HW, Sparbier K, Smirnov A, Cepek L, Trenkwalder C, Rüther E, Kornhuber J, Otto M, Wiltfang J. CSF amyloid-beta-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementia. Brain : a Journal of Neurology. 129: 1177-87. PMID 16600985 DOI: 10.1093/Brain/Awl063  0.8
2006 Lewczuk P, Beck G, Esselmann H, Bruckmoser R, Zimmermann R, Fiszer M, Bibl M, Maler JM, Kornhuber J, Wiltfang J. Effect of Sample Collection Tubes on Cerebrospinal Fluid Concentrations of Tau Proteins and Amyloid β Peptides Clinical Chemistry. 52: 332-334. PMID 16449222 DOI: 10.1373/Clinchem.2005.058776  0.8
2006 Hillemacher T, Bleich S, Wiltfang J, Weber M, Kornhuber J, Frieling H. Should aspirin be discontinued for diagnostic lumbar puncture Journal of the American Geriatrics Society. 54: 181-182. PMID 16420229 DOI: 10.1111/J.1532-5415.2005.00575_12.X  0.8
2006 Bentahir M, Nyabi O, Verhamme J, Tolia A, Horré K, Wiltfang J, Esselmann H, De Strooper B. Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms. Journal of Neurochemistry. 96: 732-42. PMID 16405513 DOI: 10.1111/J.1471-4159.2005.03578.X  0.8
2006 Henkel AW, Upmann I, Bartl CR, Bönsch D, Reichardt C, Maler JM, Nürnberger M, Umstätter R, Reulbach U, Kornhuber J, Wiltfang J. Light-induced exocytosis in cell development and differentiation. Journal of Cellular Biochemistry. 97: 1393-406. PMID 16365884 DOI: 10.1002/Jcb.20751  0.8
2006 Buerger K, Otto M, Teipel SJ, Zinkowski R, Blennow K, DeBernardis J, Kerkman D, Schröder J, Schönknecht P, Cepek L, McCulloch C, Möller H, Wiltfang J, Kretzschmar H, Hampel H. Dissociation between CSF total tau and tau protein phosphorylated at threonine 231 in Creutzfeldt-Jakob disease. Neurobiology of Aging. 27: 10-15. PMID 16298235 DOI: 10.1016/J.Neurobiolaging.2004.12.003  0.48
2006 Kornhuber J, Weigmann H, Röhrich J, Wiltfang J, Bleich S, Meineke I, Zöchling R, Härtter S, Riederer P, Hiemke C. Region specific distribution of levomepromazine in the human brain. Journal of Neural Transmission. 113: 387-397. PMID 15997416 DOI: 10.1007/S00702-005-0331-3  0.8
2006 Mollenhauer B, Steinacker P, Schlossmacher M, Locascio JJ, Wiltfang J, Trenkwalder C, Otto M. H-FABP und Tau Protein: Biomarker Kandidaten für die Demenz mit Lewy Bodies Aktuelle Neurologie. 33: 555. DOI: 10.1055/S-2006-953379  0.48
2006 Bibl M, Mollenhauer B, Esselmann H, Lewczuk P, Klafki H, Sparbier K, Smirnov A, Cepek L, Trenkwalder C, Ruther E, Kornhuber J, Otto M, Wiltfang J. P2-157: Expression of CSF amyloid beta peptide patterns Alzheimer’s disease, dementia with Lewy bodies and Parkinson’s disease dementia Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.995  0.8
2006 Lewczuk P, Vanderstichele H, Vanmechelen E, Esselmann H, Bibl M, Maler JM, Kornhuber J, Wiltfang J. P2-146: Multiplexed quantification of dementia biomarkers in the cerebrospinal fluid: A multicenter study Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.984  0.8
2006 Maler JM, Klafki HW, Esselmann H, Kunz N, Paul S, Kornhuber J, Wiltfang J. P2-052: Chicken primary neuronal cells as a powerful model for studying tau phosphorylation, APP processing and Aβ generation Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.889  0.8
2006 Svitek J, Lewczuk P, Kornhuber J, Kuwert T, Wiltfang J. P2-219: Mild cognitive impairment: Correlation of Alzheimer‘s disease neurochemical biomarkers with SPECT findings Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1058  0.8
2005 Kornhuber J, Medlin A, Bleich S, Jendrossek V, Henkel AW, Wiltfang J, Gulbins E. High activity of acid sphingomyelinase in major depression Journal of Neural Transmission. 112: 1583-1590. PMID 16245071 DOI: 10.1007/S00702-005-0374-5  0.8
2005 Wiltfang J, Lewczuk P, Riederer P, Grünblatt E, Hock C, Scheltens P, Hampel H, Vanderstichele H, Iqbal K, Galasko D, Lannfelt L, Otto M, Esselmann H, Henkel AW, Kornhuber J, et al. Consensus paper of the WFSBP Task Force on Biological Markers of Dementia: the role of CSF and blood analysis in the early and differential diagnosis of dementia. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 6: 69-84. PMID 16156480 DOI: 10.1080/15622970510029786  0.8
2005 Maler JM, Esselmann H, Wiltfang J, Kunz N, Lewczuk P, Reulbach U, Bleich S, Rüther E, Kornhuber J. Memantine inhibits ethanol-induced NMDA receptor up-regulation in rat hippocampal neurons. Brain Research. 1052: 156-62. PMID 16009352 DOI: 10.1016/J.Brainres.2005.06.017  0.8
2005 Lotz M, Ebert S, Esselmann H, Iliev AI, Prinz M, Wiazewicz N, Wiltfang J, Gerber J, Nau R. Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures Journal of Neurochemistry. 94: 289-298. PMID 15998280 DOI: 10.1111/J.1471-4159.2005.03188.X  0.8
2005 Höglund K, Syversen S, Lewczuk P, Wallin A, Wiltfang J, Blennow K. Statin treatment and a disease-specific pattern of beta-amyloid peptides in Alzheimer's disease. Experimental Brain Research. 164: 205-14. PMID 15937702 DOI: 10.1007/S00221-005-2243-8  0.8
2005 Mollenhauer B, Bibl M, Trenkwalder C, Stiens G, Cepek L, Steinacker P, Ciesielczyk B, Neubert K, Wiltfang J, Kretzschmar HA, Poser S, Otto M. Follow-up investigations in cerebrospinal fluid of patients with dementia with Lewy bodies and Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 112: 933-48. PMID 15937638 DOI: 10.1007/S00702-004-0235-7  0.8
2005 Bahn E, Wiltfang J, Nolte W, Ramadori G, Steinhoff B, Rüther E, Kurth C. Quantification of changes in electroencephalographic power spectra in a patient with Budd-Chiari-syndrome after implantation of a transjugular intrahepatic portosystemic stent shunt (TIPSS). Metabolic Brain Disease. 20: 1-6. PMID 15918545 DOI: 10.1007/S11011-005-2471-4  0.8
2005 Cepek L, Steinacker P, Mollenhauer B, Wiese B, Ciesielczyk B, Bibl M, Wiltfang J, Zerr I, Schulz-Schaeffer W, Kretzschmar HA, Poser S, Otto M. Follow-up investigations of tau protein and S-100B levels in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Dementia and Geriatric Cognitive Disorders. 19: 376-82. PMID 15802913 DOI: 10.1159/000084708  0.8
2005 Bleich S, Otto M, Zerr I, Kropp S, Kretzschmar HA, Wiltfang J. Creutzfeldt-Jakob disease and homocysteine levels in plasma and cerebrospinal fluid. Gerontology. 51: 142-4. PMID 15711082 DOI: 10.1159/000082200  0.8
2005 Steinacker P, Schwarz P, Reim K, Brechlin P, Jahn O, Kratzin H, Aitken A, Wiltfang J, Aguzzi A, Bahn E, Baxter HC, Brose N, Otto M. Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein. Molecular and Cellular Biology. 25: 1339-46. PMID 15684385 DOI: 10.1128/Mcb.25.4.1339-1346.2005  0.8
2005 Mollenhauer B, Cepek L, Bibl M, Wiltfang J, Schulz-Schaeffer WJ, Ciesielczyk B, Neumann M, Steinacker P, Kretzschmar HA, Poser S, Trenkwalder C, Otto M. Tau protein, Abeta42 and S-100B protein in cerebrospinal fluid of patients with dementia with Lewy bodies. Dementia and Geriatric Cognitive Disorders. 19: 164-70. PMID 15637452 DOI: 10.1159/000083178  0.8
2005 Bordet R, Lin KN, Salmon E, Perani D, Holthoff V, Sorbi S, Elsner A, Weisenbach S, Brand M, Lenz O, Kessler J, Luedecke S, Ortelli P, Herholz K, Scheltens P, ... ... Wiltfang J, et al. Contents Vol. 19, 2005 Dementia and Geriatric Cognitive Disorders. 19: 401-403. DOI: 10.1159/000085638  0.8
2005 Bordet R, Lin KN, Salmon E, Perani D, Holthoff V, Sorbi S, Elsner A, Weisenbach S, Brand M, Lenz O, Kessler J, Luedecke S, Ortelli P, Herholz K, Scheltens P, ... ... Wiltfang J, et al. Subject Index Vol. 19, 2005 Dementia and Geriatric Cognitive Disorders. 19: 399-400. DOI: 10.1159/000085637  0.8
2005 Mollenhauer B, Bibl M, Esselmann H, Steinacker P, Trenkwalder C, Wiltfang J, Otto M. Beta-amyloid-Peptid-Spektrum im Liquor von Patienten mit Chorea Huntington Aktuelle Neurologie. 32: 486. DOI: 10.1055/S-2005-919518  0.8
2005 Maler JM, Spitzer P, Herrmann M, Esselmann H, Lewczuk P, Kornhuber J, Wiltfang J. β-Amyloid secretion by human monocytes Pharmacopsychiatry. 38. DOI: 10.1055/S-2005-918776  0.8
2005 Maler JM, Esselmann H, Dyrks T, Klafki H, Fiszer M, Paul S, Reulbach U, Lewczuk P, Rüther E, Kornhuber J, Wiltfang J. Specific inhibition of β-amyloid peptide secretion by ZK808762 mimicks the effect of non-steroidal anti-inflammatory drugs Pharmacopsychiatry. 38. DOI: 10.1055/S-2005-918775  0.8
2005 Lewczuk P, Esselmann H, Maler JM, Bibl M, Kornhuber J, Wiltfang J. The concentrations of amyloid beta 1–42, total Tau and phospho-Tau181 in the CSF of patients with early dementia and MCI as measured with multiplexing technology Pharmacopsychiatry. 38. DOI: 10.1055/S-2005-918764  0.8
2005 Mollenhauer B, Trenkwalder C, Sixel-Döring F, Bibl M, Wiltfang J, Poser S, Otto M. Tau-protein und Beta-amyloid (1–42) im Liquor bei Lewy-Body- und Parkinson-Demenz Aktuelle Neurologie. 32: 36. DOI: 10.1055/S-2005-866643  0.8
2004 Esselmann H, Maler JM, Kunz N, Otto M, Paul S, Lewczuk P, Rüther E, Kornhuber J, Wiltfang J. Lithium decreases secretion of Abeta1-42 and C-truncated species Abeta1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Abeta1-38. Neurodegenerative Diseases. 1: 236-241. PMID 16908996 DOI: 10.1159/000080992  0.8
2004 Kornhuber J, Wiltfang J, Bleich S. The etiopathogenesis of schizophrenias. Pharmacopsychiatry. 37: 103-112. PMID 15546061 DOI: 10.1055/S-2004-832663  0.8
2004 Lewczuk P, Esselmann H, Bibl M, Paul S, Svitek J, Miertschischk J, Meyrer R, Smirnov A, Maler JM, Klein C, Otto M, Bleich S, Sperling W, Kornhuber J, Rüther E, ... Wiltfang J, et al. Electrophoretic separation of amyloid β peptides in plasma Electrophoresis. 25: 3336-3343. PMID 15490456 DOI: 10.1002/Elps.200406068  0.8
2004 Bibl M, Esselmann H, Otto M, Lewczuk P, Cepek L, Rüther E, Kornhuber J, Wiltfang J. Cerebrospinal fluid amyloid beta peptide patterns in Alzheimer's disease patients and nondemented controls depend on sample pretreatment: indication of carrier-mediated epitope masking of amyloid beta peptides. Electrophoresis. 25: 2912-8. PMID 15349929 DOI: 10.1002/Elps.200305992  0.8
2004 Lewczuk P, Esselmann H, Bibl M, Beck G, Maler JM, Otto M, Kornhuber J, Wiltfang J. Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer’s disease Journal of Molecular Neuroscience. 23: 115-122. PMID 15126697 DOI: 10.1385/Jmn:23:1-2:115  0.8
2004 Lewczuk P, Esselmann H, Otto M, Maler JM, Henkel AW, Henkel MK, Eikenberg O, Antz C, Krause WR, Reulbach U, Kornhuber J, Wiltfang J. Neurochemical diagnosis of Alzheimer's dementia by CSF Abeta42, Abeta42/Abeta40 ratio and total tau. Neurobiology of Aging. 25: 273-81. PMID 15123331 DOI: 10.1016/S0197-4580(03)00086-1  0.8
2004 Lewczuk P, Esselmann H, Groemer TW, Bibl M, Maler JM, Steinacker P, Otto M, Kornhuber J, Wiltfang J. Amyloid β peptides in cerebrospinal fluid as profiled with surface enhanced laser desorption/ionization time-of-flight mass spectrometry: evidence of novel biomarkers in Alzheimer's disease Biological Psychiatry. 55: 524-530. PMID 15023581 DOI: 10.1016/J.Biopsych.2003.10.014  0.8
2004 Otto M, Cepek L, Ratzka P, Doehlinger S, Boekhoff I, Wiltfang J, Irle E, Pergande G, Ellers-Lenz B, Windl O, Kretzschmar HA, Poser S, Prange H. Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study. Neurology. 62: 714-8. PMID 15007119 DOI: 10.1212/01.Wnl.0000113764.35026.Ef  0.8
2004 Hampel H, Teipel SJ, Fuchsberger T, Andreasen N, Wiltfang J, Otto M, Shen Y, Dodel R, Du Y, Farlow M, Möller HJ, Blennow K, Buerger K. Value of CSF β-amyloid1-42 and tau as predictors of Alzheimer's disease in patients with mild cognitive impairment Molecular Psychiatry. 9: 705-710. PMID 14699432 DOI: 10.1038/Sj.Mp.4001473  0.8
2004 Braungart E, Gerlach M, Riederer P, Baumeister R, Hoener MC, Silva OABdCe, Vieira SI, Silva EFdCe, Froelich-Fabre S, Skoglund L, Ostojic J, Kilander L, Lindau M, Rebelo S, Hartmann D, ... ... Wiltfang J, et al. DIADEM / Participants Directory Neurodegenerative Diseases. 1: 243-244. DOI: 10.1159/000082213  0.8
2004 Wiltfang J, Lewczuk P, Maler M, Smirnov A, Kornhuber J. Neurochemical early and differential diagnosis of Alzheimer’s dementia Pharmacopsychiatry. 36: 314. DOI: 10.1055/S-2003-825557  0.8
2004 Thürauf N, Lunkenheimer J, Sperling W, Bleich S, Wiltfang J, Plodeck V, Wuttke H, Rau T, Eschenhagen T, Kornhuber J. CYP2D6-Genotyping in clinical practice: Impact of Genotyp on serum concentrations of psychiatric relevant CYP2D6-substrates Pharmacopsychiatry. 36. DOI: 10.1055/S-2003-825532  0.8
2004 Esselmann H, Kunz N, Maler JM, Lewczuk P, Otto M, Ruether E, Kornhuber J, Wiltfang J. O4-04-03 Lithium decreases secretion of Abeta 1–42 and C-truncated species Abeta 1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Abeta 1–38 Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80274-4  0.8
2004 Wiltfang J, Esselmann H, Bibl M, Kornhuber J, Lewczuk P. S1-02-03 Neuroproteomic profiling of amyloid beta peptides in human CSF with SELDI-TOF MS Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80012-5  0.8
2003 Bleich S, Römer K, Wiltfang J, Kornhuber J. Glutamate and the glutamate receptor system: a target for drug action International Journal of Geriatric Psychiatry. 18. PMID 12973748 DOI: 10.1002/Gps.933  0.8
2003 Bleich S, Sperling W, Wiltfang J, Maler JM, Kornhuber J. [Excitatory neurotransmission in alcoholism]. Fortschritte Der Neurologie-Psychiatrie. 71: S36-44. PMID 12947542 DOI: 10.1055/s-2003-40504  0.8
2003 Bleich S, Wiltfang J, Kornhuber J. Memantine in moderate-to-severe Alzheimer's disease. The New England Journal of Medicine. 349: 609. PMID 12904528 DOI: 10.1056/Nejm200308073490616  0.8
2003 Wiltfang J, Esselmann H, Smirnov A, Bibl M, Cepek L, Steinacker P, Mollenhauer B, Buerger K, Hampel H, Paul S, Neumann M, Maler M, Zerr I, Kornhuber J, Kretzschmar HA, et al. Beta-amyloid peptides in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Annals of Neurology. 54: 263-7. PMID 12891683 DOI: 10.1002/Ana.10661  0.8
2003 Maler JM, Seifert W, Hüther G, Wiltfang J, Rüther E, Kornhuber J, Bleich S. Homocysteine induces cell death of rat astrocytes in vitro. Neuroscience Letters. 347: 85-8. PMID 12873734 DOI: 10.1016/S0304-3940(03)00655-4  0.8
2003 Lewczuk P, Esselmann H, Meyer M, Wollscheid V, Neumann M, Otto M, Maler JM, Rüther E, Kornhuber J, Wiltfang J. The amyloid-beta (Abeta) peptide pattern in cerebrospinal fluid in Alzheimer's disease: evidence of a novel carboxyterminally elongated Abeta peptide. Rapid Communications in Mass Spectrometry : Rcm. 17: 1291-6. PMID 12811752 DOI: 10.1002/Rcm.1048  0.8
2003 Gräsel E, Wiltfang J, Kornhuber J. Non-Drug Therapies for Dementia: An Overview of the Current Situation with Regard to Proof of Effectiveness Dementia and Geriatric Cognitive Disorders. 15: 115-125. PMID 12584426 DOI: 10.1159/000068477  0.8
2003 Maler M, Wiltfang J, Degner D, Kornhuber J, Bleich S. P.4.050 Homocysteine induces cell death of astrocytes in vitro European Neuropsychopharmacology. 13. DOI: 10.1016/S0924-977X(03)92244-9  0.8
2002 Sommer M, Dieterich A, Rüther E, Paulus W, Wiltfang J. Increased transcranial magnetic motor threshold after ECT. A case report. European Archives of Psychiatry and Clinical Neuroscience. 252: 250-2. PMID 12451468 DOI: 10.1007/S00406-002-0387-0  0.76
2002 Maeck L, Meller J, Otto M, Stiens G, Wiltfang J, Stoppe G. Abeta peptide 1-42, Tau protein and S-100B protein level in cerebrospinal fluid of three patients with primary progressive aphasia. Neuroscience Letters. 333: 33-6. PMID 12401554 DOI: 10.1016/S0304-3940(02)00968-0  0.8
2002 Baxter HC, Fraser JR, Liu WG, Forster JL, Clokie S, Steinacker P, Otto M, Bahn E, Wiltfang J, Aitken A. Specific 14-3-3 isoform detection and immunolocalization in prion diseases Biochemical Society Transactions. 30: 387-391. PMID 12196100 DOI: 10.1042/Bst0300387  0.8
2002 Nolte W, Rädisch C, Rodenbeck A, Wiltfang J, Hüfner M. Polysomnographic findings in five adult patients with pituitary insufficiency before and after cessation of human growth hormone replacement therapy Clinical Endocrinology. 56: 805-810. PMID 12072052 DOI: 10.1046/J.1365-2265.2002.01531.X  0.36
2002 Wiltfang J, Esselmann H, Bibl M, Smirnov A, Otto M, Paul S, Schmidt B, Klafki H-, Maler M, Dyrks T, Bienert M, Beyermann M, Rüther E, Kornhuber J. Highly conserved and disease‐specific patterns of carboxyterminally truncated Aβ peptides 1–37/38/39 in addition to 1–40/42 in Alzheimer's disease and in patients with chronic neuroinflammation Journal of Neurochemistry. 81: 481-496. PMID 12065657 DOI: 10.1046/J.1471-4159.2002.00818.X  0.8
2002 Scheschonka A, Bleich S, Buchwald AB, Ruther E, Wiltfang J. Development of obsessive-compulsive behaviour following cortisone treatment. Pharmacopsychiatry. 35: 72-4. PMID 11951148 DOI: 10.1055/S-2002-25022  0.8
2002 Bahn E, Nolte W, Kurth C, Ramadori G, Rüther E, Wiltfang J. Quantification of the electroencephalographic theta/alpha ratio for the assessment of portal-systemic encephalopathy following implantation of transjugular intrahepatic portosystemic stent shunt (TIPSS). Metabolic Brain Disease. 17: 19-28. PMID 11893005 DOI: 10.1023/A:1014048229754  0.8
2002 Otto M, Wiltfang J, Cepek L, Neumann M, Mollenhauer B, Steinacker P, Ciesielczyk B, Schulz-Schaeffer W, Kretzschmar HA, Poser S. Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt-Jakob disease. Neurology. 58: 192-7. PMID 11805244 DOI: 10.1212/Wnl.58.2.192  0.8
2002 Zhou D, Huether G, Wiltfang J, Hajak G, Rüther E. Serotonin Transporters in the Rat Frontal Cortex: Lack of Circadian Rhythmicity but Down‐Regulation by Food Restriction Journal of Neurochemistry. 67: 656-661. PMID 8764592 DOI: 10.1046/J.1471-4159.1996.67020656.X  0.76
2002 Kornhuber J, Wiltfang J. Women and dementia European Psychiatry. 17: 28. DOI: 10.1016/S0924-9338(02)80126-2  0.8
2001 Wiltfang J, Schenk-Daprá B, Stiens G, Bleich S, Bandelow B, Müller P, Niedmann PD, Armstrong VW, Rüther E. Clozapine-associated elevation of plasma cholinesterase. European Archives of Psychiatry and Clinical Neuroscience. 251: 269-71. PMID 11881840 DOI: 10.1007/Pl00007544  0.8
2001 Ratzka P, Schröter A, Cepek L, Henkel K, Wiltfang J, Kretzschmar HA, Prange H, Poser S, Otto M. Unaltered apoptotic behaviour of mononuclear cells from patients with sporadic Creutzfeldt-Jakob disease. Journal of Neurology. 248: 690-4. PMID 11569898 DOI: 10.1007/Pl00007834  0.8
2001 Bleich S, Bleich K, Wiltfang J, Maler JM, Kornhuber J. Glutamaterge Neurotransmission bei Schizophrenien Fortschritte Der Neurologie Psychiatrie. 69: 56-61. PMID 11533851 DOI: 10.1055/S-2001-16531  0.8
2001 Wiltfang J, Esselmann H, Cupers P, Neumann M, Kretzschmar H, Beyermann M, Schleuder D, Jahn H, Rüther E, Kornhuber J, Annaert W, De Strooper B, Saftig P. Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells. The Journal of Biological Chemistry. 276: 42645-57. PMID 11526104 DOI: 10.1074/Jbc.M102790200  0.8
2001 Sommer M, Dieterich A, Krause C, Rüther E, Wiltfang J. Subclinical pancreatitis related to mirtazapine - a case report. Pharmacopsychiatry. 34: 158-159. PMID 11518479 DOI: 10.1055/S-2001-15877  0.76
2001 Itoh N, Arai H, Urakami K, Ishiguro K, Ohno H, Hampel H, Buerger K, Wiltfang J, Otto M, Kretzschmar H, Moeller HJ, Imagawa M, Kohno H, Nakashima K, Kuzuhara S, et al. Large-scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimer's disease. Annals of Neurology. 50: 150-6. PMID 11506396 DOI: 10.1002/Ana.1054  0.48
2001 Wiltfang J, Esselmann H, Maler JM, Bleich S, Hüther G, Kornhuber J. Molecular biology of Alzheimer's dementia and its clinical relevance to early diagnosis and new therapeutic strategies. Gerontology. 47: 65-71. PMID 11287729 DOI: 10.1159/000052775  0.8
2001 Tschampa HJ, Schulz-Schaeffer W, Wiltfang J, Poser S, Otto M, Neumann M, Kretzschmar HA. Decreased CSF amyloid beta42 and normal tau levels in dementia with Lewy bodies. Neurology. 56: 576. PMID 11222819  0.8
2000 Otto M, Holthusen S, Bahn E, Sohnchen N, Wiltfang J, Geese R, Fischer A, Reimers CD. Boxing and running lead to a rise in serum levels of S-100B protein International Journal of Sports Medicine. 21: 551-555. PMID 11156273 DOI: 10.1055/s-2000-8480  0.8
2000 Bleich S, Spilker K, Kurth C, Degner D, Quintela-Schneider M, Javaheripour K, Rüther E, Kornhuber J, Wiltfang J. Oxidative stress and an altered methionine metabolism in alcoholism. Neuroscience Letters. 293: 171-4. PMID 11036188 DOI: 10.1016/S0304-3940(00)01505-6  0.8
2000 Bleich S, Kropp S, Degner D, Zerr I, Pilz J, Gleiter CH, Otto M, Rüther E, Kretzschmar HA, Wiltfang J, Kornhuber J, Poser S. Creutzfeldt-Jakob disease and oxidative stress. Acta Neurologica Scandinavica. 101: 332-4. PMID 10987323 DOI: 10.1034/J.1600-0404.2000.9S290A.X  0.8
2000 Kropp S, Schlimme J, Bleich S, Wiltfang J, Dietrich DE, Emrich HM. Diagnostische Schritte bei Alzheimer-Demenz vor Therapiebeginn mit neuen Antidementiva Fortschritte Der Neurologie Psychiatrie. 68: 257-261. PMID 10923250 DOI: 10.1055/S-2000-11808  0.8
2000 Bleich S, Degner D, Wiltfang J, Maler JM, Niedmann P, Cohrs S, Mangholz A, Porzig J, Sprung R, Rüther E, Kornhuber J. Elevated homocysteine levels in alcohol withdrawal. Alcohol and Alcoholism. 35: 351-354. PMID 10905999 DOI: 10.1093/Alcalc/35.4.351  0.8
2000 Nolte W, Ehrenreich H, Wiltfang J, Pahl K, Unterberg K, Kamrowski-Kruck H, Schindler CG, Figulla HR, Buchwald AB, Hartmann H, Ramadori G. Systemic and splanchnic endothelin-1 plasma levels in liver cirrhosis before and after transjugular intrahepatic portosystemic shunt (TIPS). Liver. 20: 60-5. PMID 10726962 DOI: 10.1034/J.1600-0676.2000.020001060.X  0.8
2000 Otto M, Esselmann H, Schulz-Shaeffer W, Neumann M, Schröter A, Ratzka P, Cepek L, Zerr I, Steinacker P, Windl O, Kornhuber J, Kretzschmar HA, Poser S, Wiltfang J. Decreased beta-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Neurology. 54: 1099-102. PMID 10720281 DOI: 10.1212/Wnl.54.5.1099  0.8
2000 Kornhuber J, Bleich S, Wiltfang J. PCP-site ligands and the glutamate hypothesis of schizophrenia European Neuropsychopharmacology. 10: 211. DOI: 10.1016/S0924-977X(00)80124-8  0.8
1999 Wiltfang J, Nolte W, Otto M, Wildberg J, Bahn E, Figulla HR, Pralle L, Hartmann H, Rüther E, Ramadori G. Elevated Serum Levels of Astroglial S100β in Patients with Liver Cirrhosis Indicate Early and Subclinical Portal-Systemic Encephalopathy Metabolic Brain Disease. 14: 239-251. PMID 10850551 DOI: 10.1023/A:1020785009005  0.76
1999 Wiltfang J, Nolte W, Heppe Jv, Bahn E, Pilz J, Hajak G, Rüther E, Ramadori G. Sleep Disorders and Portal-Systemic Encephalopathy Following Transjugular Intrahepatic Portosystemic Stent Shunt in Patients with Liver Cirrhosis Advances in Experimental Medicine and Biology. 467: 169-176. PMID 10721053 DOI: 10.1007/978-1-4615-4709-9_22  0.76
1999 Kornhuber J, Bleich S, Wiltfang J, Maler M, Parsons CG. Flupirtine shows functional NMDA receptor antagonism by enhancing Mg2+ block via activation of voltage independent potassium channels Journal of Neural Transmission. 106: 857-867. PMID 10599868 DOI: 10.1007/S007020050206  0.8
1999 Kornhuber J, Maler M, Wiltfang J, Bleich S, Degner D, Rüther E. Neuronale Kaliumkanalöffnung durch Flupirtin Fortschritte Der Neurologie Psychiatrie. 67: 466-475. PMID 10596368 DOI: 10.1055/S-2007-994997  0.8
1999 Wiltfang J, Otto M, Baxter HC, Bodemer M, Steinacker P, Bahn E, Zerr I, Kornhuber J, Kretzschmar HA, Poser S, Rüther E, Aitken A. Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Journal of Neurochemistry. 73: 2485-90. PMID 10582609 DOI: 10.1046/J.1471-4159.1999.0732485.X  0.8
1999 Steinhoff BJ, Tumani H, Otto M, Mursch K, Wiltfang J, Herrendorf G, Bittermann HJ, Felgenhauer K, Paulus W, Markakis E. Cisternal S100 protein and neuron-specific enolase are elevated and site-specific markers in intractable temporal lobe epilepsy. Epilepsy Research. 36: 75-82. PMID 10463853 DOI: 10.1016/S0920-1211(99)00026-1  0.8
1999 Otto M, Wiltfang J, Poser S, Kornhuber J, Burger K, Padberg F, Moller HJ, Hampel H. Tau protein: A potential biological indicator for early recognition of Alzheimer's disease [1] (multiple letters) Nervenarzt. 70: 668-670. PMID 10434268 DOI: 10.1007/S001150050494  0.8
1999 Kornhuber J, Jellinger K, Wiltfang J, Leblhuber F, Riederer P. The N-methyl-D-aspartate receptor channel blocker amantadine does not cause histopathological alterations in human brain tissue. Acta Neuropathologica. 98: 85-90. PMID 10412804 DOI: 10.1007/S004010051054  0.8
1999 Beekes M, Otto M, Wiltfang J, Bahn E, Poser S, Baier M. Late increase of serum S100 β protein levels in hamsters after oral or intraperitoneal infection with scrapie Journal of Infectious Diseases. 180: 518-520. PMID 10395873 DOI: 10.1086/314907  0.8
1999 Tumani H, Otto M, Gefeller O, Wiltfang J, Herrendorf G, Mogge S, Steinhoff BJ. Kinetics Of Serum Neuron-Specific Enolase And Prolactin In Patients After Single Epileptic Seizures Epilepsia. 40: 713-718. PMID 10368068 DOI: 10.1111/J.1528-1157.1999.Tb00768.X  0.48
1999 Kornhuber J, Schultz A, Wiltfang J, Meineke I, Gleiter CH, Zöchling R, Boissl K, Leblhuber F, Riederer P. Persistence of haloperidol in human brain tissue. American Journal of Psychiatry. 156: 885-890. PMID 10360127 DOI: 10.1176/Ajp.156.6.885  0.8
1999 Hulstaert F, Blennow K, Ivanoiu A, Schoonderwaldt HC, Riemenschneider M, De Deyn PP, Bancher C, Cras P, Wiltfang J, Mehta PD, Iqbal K, Pottel H, Vanmechelen E, Vanderstichele H. Improved discrimination of AD patients using beta-amyloid(1-42) and tau levels in CSF. Neurology. 52: 1555-62. PMID 10331678 DOI: 10.1212/Wnl.52.8.1555  0.8
1999 Wiltfang J, Klotz S, Jordan W, Cohrs S, Engelbe W, Hajak G. First results on daytime submandibular electrostimulation of suprahyoidal muscles to prevent night-time hypopharyngeal collapse in obstructive sleep apnea syndrome International Journal of Oral and Maxillofacial Surgery. 28: 21-25. DOI: 10.1016/S0901-5027(99)80670-5  0.36
1998 Wiltfang J, Nolte W, Weissenborn K, Kornhuber J, Rüther E. Psychiatric aspects of portal-systemic encephalopathy. Metabolic Brain Disease. 13: 379-389. PMID 10206828 DOI: 10.1023/A:1020697127718  0.8
1998 Otto M, Beekes M, Wiltfang J, Bahn E, Poser S, Diringer H. Elevated levels of serum S100 beta protein in scrapie hamsters [1] Journal of Neurovirology. 4: 572-573. PMID 9839656 DOI: 10.3109/13550289809113503  0.8
1998 Nolte W, Wiltfang J, Schindler C, Münke H, Unterberg K, Zumhasch U, Figulla HR, Werner G, Hartmann H, Ramadori G. Portosystemic hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in patients with cirrhosis: Clinical, laboratory, psychometric, and electroencephalographic investigations Hepatology. 28: 1215-1225. PMID 9794904 DOI: 10.1002/Hep.510280508  0.36
1998 Nolte W, Wiltfang J, Schindler CG, Unterberg K, Finkenstaedt M, Niedmann PD, Hartmann H, Ramadori G. Bright basal ganglia in T1-weighted magnetic resonance images are frequent in patients with portal vein thrombosis without liver cirrhosis and not suggestive of hepatic encephalopathy. Journal of Hepatology. 29: 443-449. PMID 9764992 DOI: 10.1016/S0168-8278(98)80063-9  0.36
1998 Kornhuber J, Wiltfang J, Kornbuber J. The role of glutamate in dementia. Journal of Neural Transmission. Supplementum. 53: 277-87. PMID 9700664 DOI: 10.1007/978-3-7091-6467-9_24  0.4
1998 Otto M, Wiltfang J, Schütz E, Zerr I, Otto A, Pfahlberg A, Gefeller O, Uhr M, Giese A, Weber T, Kretzschmar HA, Poser S. Diagnosis of Creutzfeldt-Jakob disease by measurement of S100 protein in serum: prospective case-control study. Bmj (Clinical Research Ed.). 316: 577-82. PMID 9518907  0.8
1998 Otto M, Bahn E, Wiltfang J, Boekhoff I, Beuche W. Decrease of S100 beta protein in serum of patients with amyotrophic lateral sclerosis Neuroscience Letters. 240: 171-173. PMID 9502231 DOI: 10.1016/S0304-3940(97)00947-6  0.48
1998 Zerr I, Bodemer M, Gefeller O, Otto M, Poser S, Wiltfang J, Windl O, Kretzschmar HA, Weber T. Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease. Annals of Neurology. 43: 32-40. PMID 9450766 DOI: 10.1002/Ana.410430109  0.8
1997 Huether G, Zhou D, Schmidt S, Wiltfang J, Rüther E. Long-term food restriction down-regulates the density of serotonin transporters in the rat frontal cortex Biological Psychiatry. 41: 1174-1180. PMID 9171908 DOI: 10.1016/S0006-3223(96)00265-X  0.76
1997 Wiltfang J, Smirnov A, Schnierstein B, Kelemen G, Matthies U, Klafki H, Staufenbiel M, Hüther G, Rüther E, Kornhuber J. Improved electrophoretic separation and immunoblotting of beta‐amyloid (Aβ) peptides 1–40, 1–42, and 1–43 Electrophoresis. 18: 527-532. PMID 9150936 DOI: 10.1002/Elps.1150180332  0.8
1997 Otto M, Wiltfang J, Tumani H, Zerr I, Lantsch M, Kornhuber J, Weber T, Kretzschmar HA, Poser S. Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Neuroscience Letters. 225: 210-2. PMID 9147407 DOI: 10.1016/S0304-3940(97)00215-2  0.8
1996 Michel U, Schneider O, Kirchhof C, Meisel S, Smirnov A, Wiltfang J, Rieckmann P. Production Of Follistatin In Porcine Endothelial Cells : Differential Regulation By Bacterial Compounds And The Synthetic Glucocorticoid Ru 28362 Endocrinology. 137: 4925-4934. PMID 8895365 DOI: 10.1210/Endo.137.11.8895365  0.56
1996 Klafki H, Wiltfang J, Staufenbiel M. Electrophoretic Separation of βA4 Peptides (1–40) and (1–42) Analytical Biochemistry. 237: 24-29. PMID 8660532 DOI: 10.1006/Abio.1996.0195  0.56
1991 Müller-Spahn F, Hüther G, Schinschke S, Stoppe G, Wiltfang J. Serum melatonin, 5-HT and tryptophan levels in blood and CSF in the diagnosis of early dementia and depressive pseudodementia European Neuropsychopharmacology. 1: 458. DOI: 10.1016/0924-977X(91)90675-K  0.64
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