Lutz Birnbaumer - Publications

Affiliations: 
1971-1974 Northwestern University, Evanston, IL 
 1975-1994 Baylor College of Medicine, Houston, TX 
 1994-2001 University of California, Los Angeles, Los Angeles, CA 
 2001-2013 National Institute of Environmental Health Sciences (NIEHS), Durham, NC, United States 
Website:
https://www.niehs.nih.gov/news/newsroom/releases/2001/july09/index.cfm

341 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Egorov AV, Schumacher D, Medert R, Birnbaumer L, Freichel M, Draguhn A. TRPC channels are not required for graded persistent activity in entorhinal cortex neurons. Hippocampus. PMID 31002217 DOI: 10.1002/hipo.23094  0.36
2019 Tiapko O, Shrestha N, Lindinger S, Guedes de la Cruz G, Graziani A, Klec C, Butorac C, Graier WF, Kubista H, Freichel M, Birnbaumer L, Romanin C, Glasnov T, Groschner K. Lipid-independent control of endothelial and neuronal TRPC3 channels by light. Chemical Science. 10: 2837-2842. PMID 30997005 DOI: 10.1039/c8sc05536j  0.36
2019 Li ZW, Sun B, Gong T, Guo S, Zhang J, Wang J, Sugawara A, Jiang M, Yan J, Gurary A, Zhen X, Gao B, Xiao SY, Chen W, Ma C, ... ... Birnbaumer L, et al. GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Downregulating Expression of GNAI2. Gastroenterology. PMID 30836096 DOI: 10.1053/j.gastro.2019.02.040  0.4
2018 Hou X, Xiao H, Zhang Y, Zeng X, Huang M, Chen X, Birnbaumer L, Liao Y. Transient receptor potential channel 6 knockdown prevents apoptosis of renal tubular epithelial cells upon oxidative stress via autophagy activation. Cell Death & Disease. 9: 1015. PMID 30282964 DOI: 10.1038/s41419-018-1052-5  0.52
2018 Sachdeva R, Schlotterer A, Schumacher D, Matka C, Mathar I, Dietrich N, Medert R, Kriebs U, Lin J, Nawroth P, Birnbaumer L, Fleming T, Hammes HP, Freichel M. TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation. Molecular Metabolism. PMID 29373286 DOI: 10.1016/j.molmet.2018.01.003  0.36
2017 Liu B, He X, Li S, Xu B, Birnbaumer L, Liao Y. Deletion of diacylglycerol-responsive TRPC genes attenuates diabetic nephropathy by inhibiting activation of the TGFβ1 signaling pathway. American Journal of Translational Research. 9: 5619-5630. PMID 29312514  0.52
2017 Belkacemi T, Niermann A, Hofmann L, Wissenbach U, Birnbaumer L, Leidinger P, Backes C, Meese E, Keller A, Bai X, Scheller A, Kirchhoff F, Philipp SE, Weissgerber P, Flockerzi V, et al. TRPC1- and TRPC3-dependent Ca(2+) signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo. Glia. PMID 28636132 DOI: 10.1002/glia.23180  0.36
2017 He X, Li S, Liu B, Susperreguy S, Formoso K, Yao J, Kang J, Shi A, Birnbaumer L, Liao Y. Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries. Proceedings of the National Academy of Sciences of the United States of America. PMID 28526717 DOI: 10.1073/pnas.1621384114  0.52
2017 Danielczok J, Hertz L, Ruppenthal S, Kaiser E, Petkova-Kirova P, Bogdanova A, Krause E, Lipp P, Freichel M, Kaestner L, Birnbaumer L. Does Erythropoietin Regulate TRPC Channels in Red Blood Cells? Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 41: 1219-1228. PMID 28268218 DOI: 10.1159/000464384  0.36
2016 Chrétien C, Fenech C, Liénard F, Grall S, Chevalier C, Chaudy S, Brenachot X, Berges R, Louche K, Stark R, Nédélec E, Laderrière A, Andrews ZB, Benani A, Flockerzi V, ... ... Birnbaumer L, et al. Transient Receptor Potential Canonical 3 (TRPC3) Channels are Required for Hypothalamic Glucose Detection and Energy Homeostasis. Diabetes. PMID 27899482 DOI: 10.2337/db16-1114  0.36
2016 Chen X, Lu M, He X, Ma L, Birnbaumer L, Liao Y. TRPC3/6/7 Knockdown Protects the Brain from Cerebral Ischemia Injury via Astrocyte Apoptosis Inhibition and Effects on NF-кB Translocation. Molecular Neurobiology. PMID 27826749 DOI: 10.1007/s12035-016-0227-2  0.52
2016 Choi JM, Kim SS, Choi CI, Cha HL, Oh HH, Ghil S, Lee YD, Birnbaumer L, Suh-Kim H. Development of the main olfactory system and main olfactory epithelium-dependent male mating behavior are altered in Go-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 27625425 DOI: 10.1073/pnas.1613026113  1
2016 Han JW, Lee YH, Yoen SI, Abramowitz J, Birnbaumer L, Lee MG, Kim JY. Resistance to pathologic cardiac hypertrophy and reduced expression of CaV1.2 in Trpc3-depleted mice. Molecular and Cellular Biochemistry. PMID 27522668 DOI: 10.1007/s11010-016-2784-0  1
2016 Chaudhuri P, Rosenbaum MA, Sinharoy P, Damron DS, Birnbaumer L, Graham LM. Membrane translocation of TRPC6 channels and endothelial migration are regulated by calmodulin and PI3 kinase activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858457 DOI: 10.1073/pnas.1600371113  1
2015 Riazanski V, Gabdoulkhakova AG, Boynton LS, Eguchi RR, Deriy LV, Hogarth DK, Loaëc N, Oumata N, Galons H, Brown ME, Shevchenko P, Gallan AJ, Yoo SG, Naren AP, Villereal ML, ... ... Birnbaumer L, et al. TRPC6 channel translocation into phagosomal membrane augments phagosomal function. Proceedings of the National Academy of Sciences of the United States of America. 112: E6486-95. PMID 26604306 DOI: 10.1073/pnas.1518966112  1
2015 Keller K, Maaß M, Dizayee S, Leiss V, Annala S, Köth J, Seemann W, Müller-Ehmsen J, Mohr K, Nürnberg B, Engelhardt S, Herzig S, Birnbaumer L, Matthes J. Lack of Gαi2 leads to dilative cardiomyopathy and increased mortality in β1-adrenoceptor overexpressing mice. Cardiovascular Research. PMID 26464333 DOI: 10.1093/cvr/cvv235  1
2015 Birnbaumer L. From GTP and G proteins to TRPC channels: a personal account. Journal of Molecular Medicine (Berlin, Germany). 93: 941-53. PMID 26377676 DOI: 10.1007/s00109-015-1328-5  1
2015 Villanueva H, Visbal AP, Obeid NF, Ta AQ, Faruki AA, Wu MF, Hilsenbeck SG, Shaw CA, Yu P, Plummer NW, Birnbaumer L, Lewis MT. An essential role for Gαi2 in Smoothened-stimulated epithelial cell proliferation in the mammary gland. Science Signaling. 8: ra92. PMID 26373672 DOI: 10.1126/scisignal.aaa7355  1
2015 Camacho Londoño JE, Tian Q, Hammer K, Schröder L, Camacho Londoño J, Reil JC, He T, Oberhofer M, Mannebach S, Mathar I, Philipp SE, Tabellion W, Schweda F, Dietrich A, Kaestner L, ... ... Birnbaumer L, et al. A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling. European Heart Journal. PMID 26069213 DOI: 10.1093/eurheartj/ehv250  1
2015 Zhou X, Ye Y, Sun Y, Li X, Wang W, Privratsky B, Tan S, Zhou Z, Huang C, Wei YQ, Birnbaumer L, Singh BB, Wu M. Transient Receptor Potential Channel 1 Deficiency Impairs Host Defense and Proinflammatory Responses to Bacterial Infection by Regulating Protein Kinase Cα Signaling. Molecular and Cellular Biology. 35: 2729-39. PMID 26031335 DOI: 10.1128/MCB.00256-15  1
2015 Devanathan V, Hagedorn I, Köhler D, Pexa K, Cherpokova D, Kraft P, Singh M, Rosenberger P, Stoll G, Birnbaumer L, Piekorz RP, Beer-Hammer S, Nieswandt B, Nürnberg B. Platelet Gi protein Gαi2 is an essential mediator of thrombo-inflammatory organ damage in mice. Proceedings of the National Academy of Sciences of the United States of America. 112: 6491-6. PMID 25944935 DOI: 10.1073/pnas.1505887112  1
2015 Sun Y, Birnbaumer L, Singh BB. TRPC1 Regulates Calcium-Activated Chloride Channels in Salivary Gland Cells. Journal of Cellular Physiology. PMID 25899321 DOI: 10.1002/jcp.25017  1
2015 Smedlund KB, Birnbaumer L, Vazquez G. Increased size and cellularity of advanced atherosclerotic lesions in mice with endothelial overexpression of the human TRPC3 channel. Proceedings of the National Academy of Sciences of the United States of America. 112: E2201-6. PMID 25870279 DOI: 10.1073/pnas.1505410112  1
2015 Li X, Wang D, Chen Z, Lu E, Wang Z, Duan J, Tian W, Wang Y, You L, Zou Y, Cheng Y, Zhu Q, Wan X, Xi T, Birnbaumer L, et al. Gαi1 and Gαi3 regulate macrophage polarization by forming a complex containing CD14 and Gab1. Proceedings of the National Academy of Sciences of the United States of America. 112: 4731-6. PMID 25825741 DOI: 10.1073/pnas.1503779112  0.4
2014 Domes K, Patrucco E, Loga F, Dietrich A, Birnbaumer L, Wegener JW, Hofmann F. Murine cardiac growth, TRPC channels, and cGMP kinase I. Pflugers Archiv : European Journal of Physiology. PMID 25547873 DOI: 10.1007/s00424-014-1682-0  1
2014 Lutas A, Birnbaumer L, Yellen G. Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 16336-47. PMID 25471572 DOI: 10.1523/JNEUROSCI.1357-14.2014  1
2014 Yeon SI, Kim JY, Yeon DS, Abramowitz J, Birnbaumer L, Muallem S, Lee YH. Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries. Plos One. 9: e110413. PMID 25310225 DOI: 10.1371/journal.pone.0110413  1
2014 Leiss V, Flockerzie K, Novakovic A, Rath M, Schönsiegel A, Birnbaumer L, Schürmann A, Harteneck C, Nürnberg B. Insulin secretion stimulated by L-arginine and its metabolite L-ornithine depends on Gα(i2). American Journal of Physiology. Endocrinology and Metabolism. 307: E800-12. PMID 25205820 DOI: 10.1152/ajpendo.00337.2014  1
2014 Kochukov MY, Balasubramanian A, Abramowitz J, Birnbaumer L, Marrelli SP. Activation of endothelial transient receptor potential C3 channel is required for small conductance calcium-activated potassium channel activation and sustained endothelial hyperpolarization and vasodilation of cerebral artery. Journal of the American Heart Association. 3. PMID 25142058 DOI: 10.1161/JAHA.114.000913  1
2014 Du J, Ma X, Shen B, Huang Y, Birnbaumer L, Yao X. TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric channel. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4677-85. PMID 25114176 DOI: 10.1096/fj.14-251652  1
2014 Phelan KD, Shwe UT, Abramowitz J, Birnbaumer L, Zheng F. Critical role of canonical transient receptor potential channel 7 in initiation of seizures. Proceedings of the National Academy of Sciences of the United States of America. 111: 11533-8. PMID 25049394 DOI: 10.1073/pnas.1411442111  1
2014 Solanki S, Dube PR, Tano JY, Birnbaumer L, Vazquez G. Reduced endoplasmic reticulum stress-induced apoptosis and impaired unfolded protein response in TRPC3-deficient M1 macrophages. American Journal of Physiology. Cell Physiology. 307: C521-31. PMID 25031020 DOI: 10.1152/ajpcell.00369.2013  1
2014 Liao Y, Abramowitz J, Birnbaumer L. The TRPC family of TRP channels: roles inferred (mostly) from knockout mice and relationship to ORAI proteins. Handbook of Experimental Pharmacology. 223: 1055-75. PMID 24961980 DOI: 10.1007/978-3-319-05161-1_14  1
2014 Oboti L, Pérez-Gómez A, Keller M, Jacobi E, Birnbaumer L, Leinders-Zufall T, Zufall F, Chamero P. A wide range of pheromone-stimulated sexual and reproductive behaviors in female mice depend on G protein Gαo. Bmc Biology. 12: 31. PMID 24886577 DOI: 10.1186/1741-7007-12-31  1
2014 Köhler D, Devanathan V, Bernardo de Oliveira Franz C, Eldh T, Novakovic A, Roth JM, Granja T, Birnbaumer L, Rosenberger P, Beer-Hammer S, Nürnberg B. Gαi2- and Gαi3-deficient mice display opposite severity of myocardial ischemia reperfusion injury. Plos One. 9: e98325. PMID 24858945 DOI: 10.1371/journal.pone.0098325  1
2014 Ball CB, Rodriguez KF, Stumpo DJ, Ribeiro-Neto F, Korach KS, Blackshear PJ, Birnbaumer L, Ramos SB. The RNA-binding protein, ZFP36L2, influences ovulation and oocyte maturation. Plos One. 9: e97324. PMID 24830504 DOI: 10.1371/journal.pone.0097324  1
2014 Choi CI, Yoon SP, Choi JM, Kim SS, Lee YD, Birnbaumer L, Suh-Kim H. Simultaneous deletion of floxed genes mediated by CaMKIIα-Cre in the brain and in male germ cells: application to conditional and conventional disruption of Goα. Experimental & Molecular Medicine. 46: e93. PMID 24787734 DOI: 10.1038/emm.2014.14  1
2014 Ilatovskaya DV, Palygin O, Chubinskiy-Nadezhdin V, Negulyaev YA, Ma R, Birnbaumer L, Staruschenko A. Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli. Kidney International. 86: 506-14. PMID 24646854 DOI: 10.1038/ki.2014.71  1
2014 Wang Z, Dela Cruz R, Ji F, Guo S, Zhang J, Wang Y, Feng GS, Birnbaumer L, Jiang M, Chu WM. G(i)α proteins exhibit functional differences in the activation of ERK1/2, Akt and mTORC1 by growth factors in normal and breast cancer cells. Cell Communication and Signaling : Ccs. 12: 10. PMID 24521094 DOI: 10.1186/1478-811X-12-10  1
2014 Seo K, Rainer PP, Shalkey Hahn V, Lee DI, Jo SH, Andersen A, Liu T, Xu X, Willette RN, Lepore JJ, Marino JP, Birnbaumer L, Schnackenberg CG, Kass DA. Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. 111: 1551-6. PMID 24453217 DOI: 10.1073/pnas.1308963111  1
2014 Seo K, Rainer PP, Lee DI, Hao S, Bedja D, Birnbaumer L, Cingolani OH, Kass DA. Hyperactive adverse mechanical stress responses in dystrophic heart are coupled to transient receptor potential canonical 6 and blocked by cGMP-protein kinase G modulation. Circulation Research. 114: 823-32. PMID 24449818 DOI: 10.1161/CIRCRESAHA.114.302614  1
2014 Minetti GC, Feige JN, Bombard F, Heier A, Morvan F, Nürnberg B, Leiss V, Birnbaumer L, Glass DJ, Fornaro M. Gαi2 signaling is required for skeletal muscle growth, regeneration, and satellite cell proliferation and differentiation. Molecular and Cellular Biology. 34: 619-30. PMID 24298018 DOI: 10.1128/MCB.00957-13  1
2014 Xia Y, Yang XR, Fu Z, Paudel O, Abramowitz J, Birnbaumer L, Sham JS. Classical transient receptor potential 1 and 6 contribute to hypoxic pulmonary hypertension through differential regulation of pulmonary vascular functions. Hypertension. 63: 173-80. PMID 24144647 DOI: 10.1161/HYPERTENSIONAHA.113.01902  1
2014 Tano JY, Solanki S, Lee RH, Smedlund K, Birnbaumer L, Vazquez G. Bone marrow deficiency of TRPC3 channel reduces early lesion burden and necrotic core of advanced plaques in a mouse model of atherosclerosis. Cardiovascular Research. 101: 138-44. PMID 24101197 DOI: 10.1093/cvr/cvt231  1
2014 Shi J, Birnbaumer L, Large WA, Albert AP. Myristoylated alanine-rich C kinase substrate coordinates native TRPC1 channel activation by phosphatidylinositol 4,5-bisphosphate and protein kinase C in vascular smooth muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 244-55. PMID 24022404 DOI: 10.1096/fj.13-238022  1
2014 Seo K, Rainer PP, Hahn VS, Lee DI, Jo SH, Andersen A, Liu T, Xu X, Willette RN, Lepore JJ, Marino JP, Birnbaumer L, Schnackenberg CG, Kass DA. Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy (Proceedings of the National Academy of Sciences of the United States of America (2014) 111, 4, (1551-1556) doi:10.1073/pnas.1308963111) Proceedings of the National Academy of Sciences of the United States of America. 111: 6115. DOI: 10.1073/pnas.1405263111  1
2013 Sekerková G, Kim JA, Nigro MJ, Becker EB, Hartmann J, Birnbaumer L, Mugnaini E, Martina M. Early onset of ataxia in moonwalker mice is accompanied by complete ablation of type II unipolar brush cells and Purkinje cell dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 19689-94. PMID 24336732 DOI: 10.1523/JNEUROSCI.2294-13.2013  1
2013 Colaneri A, Wang T, Pagadala V, Kittur J, Staffa NG, Peddada SD, Isganaitis E, Patti ME, Birnbaumer L. A minimal set of tissue-specific hypomethylated CpGs constitute epigenetic signatures of developmental programming. Plos One. 8: e72670. PMID 24069155 DOI: 10.1371/journal.pone.0072670  1
2013 Hwang IY, Park C, Luong T, Harrison KA, Birnbaumer L, Kehrl JH. The loss of Gnai2 and Gnai3 in B cells eliminates B lymphocyte compartments and leads to a hyper-IgM like syndrome. Plos One. 8: e72596. PMID 23977324 DOI: 10.1371/journal.pone.0072596  1
2013 Ezan J, Lasvaux L, Gezer A, Novakovic A, May-Simera H, Belotti E, Lhoumeau AC, Birnbaumer L, Beer-Hammer S, Borg JP, Le Bivic A, Nürnberg B, Sans N, Montcouquiol M. Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton. Nature Cell Biology. 15: 1107-15. PMID 23934215 DOI: 10.1038/ncb2819  1
2013 Boudes M, Uvin P, Pinto S, Freichel M, Birnbaumer L, Voets T, De Ridder D, Vennekens R. Crucial role of TRPC1 and TRPC4 in cystitis-induced neuronal sprouting and bladder overactivity. Plos One. 8: e69550. PMID 23922735 DOI: 10.1371/journal.pone.0069550  1
2013 Loga F, Domes K, Freichel M, Flockerzi V, Dietrich A, Birnbaumer L, Hofmann F, Wegener JW. The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone. Cardiovascular Research. 100: 280-7. PMID 23832809 DOI: 10.1093/cvr/cvt176  1
2013 Harper MT, Londoño JE, Quick K, Londoño JC, Flockerzi V, Philipp SE, Birnbaumer L, Freichel M, Poole AW. Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure. Science Signaling. 6: ra50. PMID 23800468 DOI: 10.1126/scisignal.2003701  1
2013 Feng S, Li H, Tai Y, Huang J, Su Y, Abramowitz J, Zhu MX, Birnbaumer L, Wang Y. Canonical transient receptor potential 3 channels regulate mitochondrial calcium uptake. Proceedings of the National Academy of Sciences of the United States of America. 110: 11011-6. PMID 23776229 DOI: 10.1073/pnas.1309531110  1
2013 Ong EC, Nesin V, Long CL, Bai CX, Guz JL, Ivanov IP, Abramowitz J, Birnbaumer L, Humphrey MB, Tsiokas L. A TRPC1 protein-dependent pathway regulates osteoclast formation and function. The Journal of Biological Chemistry. 288: 22219-32. PMID 23770672 DOI: 10.1074/jbc.M113.459826  1
2013 Sebastian S, Ang R, Abramowitz J, Weinstein LS, Chen M, Ludwig A, Birnbaumer L, Tinker A. The in vivo regulation of heart rate in the murine sinoatrial node by stimulatory and inhibitory heterotrimeric G proteins. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 305: R435-42. PMID 23697798 DOI: 10.1152/ajpregu.00037.2013  1
2013 Dasari S, Abramowitz J, Birnbaumer L, Gulledge AT. Do canonical transient receptor potential channels mediate cholinergic excitation of cortical pyramidal neurons? Neuroreport. 24: 550-4. PMID 23652155 DOI: 10.1097/WNR.0b013e3283621344  1
2013 Medic N, Desai A, Olivera A, Abramowitz J, Birnbaumer L, Beaven MA, Gilfillan AM, Metcalfe DD. Knockout of the Trpc1 gene reveals that TRPC1 can promote recovery from anaphylaxis by negatively regulating mast cell TNF-α production. Cell Calcium. 53: 315-26. PMID 23489970 DOI: 10.1016/j.ceca.2013.02.001  1
2013 Wong AC, Birnbaumer L, Housley GD. Canonical transient receptor potential channel subtype 3-mediated hair cell Ca(2+) entry regulates sound transduction and auditory neurotransmission. The European Journal of Neuroscience. 37: 1478-86. PMID 23442051 DOI: 10.1111/ejn.12158  1
2013 Yeo M, Berglund K, Hanna M, Guo JU, Kittur J, Torres MD, Abramowitz J, Busciglio J, Gao Y, Birnbaumer L, Liedtke WB. Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter. Proceedings of the National Academy of Sciences of the United States of America. 110: 4315-20. PMID 23440186 DOI: 10.1073/pnas.1300959110  1
2013 Baron J, Blex C, Rohrbeck A, Rachakonda SK, Birnbaumer L, Ahnert-Hilger G, Brunk I. The α-subunit of the trimeric GTPase Go2 regulates axonal growth. Journal of Neurochemistry. 124: 782-94. PMID 23373526 DOI: 10.1111/jnc.12123  1
2013 Phelan KD, Shwe UT, Abramowitz J, Wu H, Rhee SW, Howell MD, Gottschall PE, Freichel M, Flockerzi V, Birnbaumer L, Zheng F. Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms. Molecular Pharmacology. 83: 429-38. PMID 23188715 DOI: 10.1124/mol.112.082271  1
2012 Plummer NW, Spicher K, Malphurs J, Akiyama H, Abramowitz J, Nürnberg B, Birnbaumer L. Development of the mammalian axial skeleton requires signaling through the Gα(i) subfamily of heterotrimeric G proteins. Proceedings of the National Academy of Sciences of the United States of America. 109: 21366-71. PMID 23236180 DOI: 10.1073/pnas.1219810110  1
2012 Suresh Babu S, Wojtowicz A, Freichel M, Birnbaumer L, Hecker M, Cattaruzza M. Mechanism of stretch-induced activation of the mechanotransducer zyxin in vascular cells. Science Signaling. 5: ra91. PMID 23233529 DOI: 10.1126/scisignal.2003173  1
2012 Xie J, Cha SK, An SW, Kuro-O M, Birnbaumer L, Huang CL. Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart. Nature Communications. 3: 1238. PMID 23212367 DOI: 10.1038/ncomms2240  1
2012 Liu Y, Zheng X, Mueller GA, Sobhany M, DeRose EF, Zhang Y, London RE, Birnbaumer L. Crystal structure of calmodulin binding domain of orai1 in complex with Ca2+ calmodulin displays a unique binding mode. The Journal of Biological Chemistry. 287: 43030-41. PMID 23109337 DOI: 10.1074/jbc.M112.380964  1
2012 Tauseef M, Knezevic N, Chava KR, Smith M, Sukriti S, Gianaris N, Obukhov AG, Vogel SM, Schraufnagel DE, Dietrich A, Birnbaumer L, Malik AB, Mehta D. TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation. The Journal of Experimental Medicine. 209: 1953-68. PMID 23045603 DOI: 10.1084/jem.20111355  1
2012 Davis J, Burr AR, Davis GF, Birnbaumer L, Molkentin JD. A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo. Developmental Cell. 23: 705-15. PMID 23022034 DOI: 10.1016/j.devcel.2012.08.017  1
2012 Peters M, Trembovler V, Alexandrovich A, Parnas M, Birnbaumer L, Minke B, Shohami E. Carvacrol together with TRPC1 elimination improve functional recovery after traumatic brain injury in mice. Journal of Neurotrauma. 29: 2831-4. PMID 22994850 DOI: 10.1089/neu.2012.2575  1
2012 Yildirim E, Carey MA, Card JW, Dietrich A, Flake GP, Zhang Y, Bradbury JA, Rebolloso Y, Germolec DR, Morgan DL, Zeldin DC, Birnbaumer L. Severely blunted allergen-induced pulmonary Th2 cell response and lung hyperresponsiveness in type 1 transient receptor potential channel-deficient mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L539-49. PMID 22797250 DOI: 10.1152/ajplung.00389.2011  1
2012 Quick K, Zhao J, Eijkelkamp N, Linley JE, Rugiero F, Cox JJ, Raouf R, Gringhuis M, Sexton JE, Abramowitz J, Taylor R, Forge A, Ashmore J, Kirkwood N, Kros CJ, ... ... Birnbaumer L, et al. TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells. Open Biology. 2: 120068. PMID 22724068 DOI: 10.1098/rsob.120068  1
2012 Senadheera S, Kim Y, Grayson TH, Toemoe S, Kochukov MY, Abramowitz J, Housley GD, Bertrand RL, Chadha PS, Bertrand PP, Murphy TV, Tare M, Birnbaumer L, Marrelli SP, Sandow SL. Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity. Cardiovascular Research. 95: 439-47. PMID 22721989 DOI: 10.1093/cvr/cvs208  1
2012 Molnar T, Barabas P, Birnbaumer L, Punzo C, Kefalov V, Križaj D. Store-operated channels regulate intracellular calcium in mammalian rods. The Journal of Physiology. 590: 3465-81. PMID 22674725 DOI: 10.1113/jphysiol.2012.234641  1
2012 Ustyugova IV, Zhi L, Abramowitz J, Birnbaumer L, Wu MX. IEX-1 deficiency protects against colonic cancer. Molecular Cancer Research : McR. 10: 760-7. PMID 22550081 DOI: 10.1158/1541-7786.MCR-11-0556  1
2012 Stroh O, Freichel M, Kretz O, Birnbaumer L, Hartmann J, Egger V. NMDA receptor-dependent synaptic activation of TRPC channels in olfactory bulb granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5737-46. PMID 22539836 DOI: 10.1523/JNEUROSCI.3753-11.2012  1
2012 Selvaraj S, Sun Y, Watt JA, Wang S, Lei S, Birnbaumer L, Singh BB. Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling. The Journal of Clinical Investigation. 122: 1354-67. PMID 22446186 DOI: 10.1172/JCI61332  1
2012 Zanou N, Schakman O, Louis P, Ruegg UT, Dietrich A, Birnbaumer L, Gailly P. Trpc1 ion channel modulates phosphatidylinositol 3-kinase/Akt pathway during myoblast differentiation and muscle regeneration. The Journal of Biological Chemistry. 287: 14524-34. PMID 22399301 DOI: 10.1074/jbc.M112.341784  1
2012 Tang G, Wang Y, Park S, Bajpayee NS, Vi D, Nagaoka Y, Birnbaumer L, Jiang M. Go2 G protein mediates galanin inhibitory effects on insulin release from pancreatic β cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 2636-41. PMID 22308501 DOI: 10.1073/pnas.1200100109  1
2012 Gugger OS, Hartmann J, Birnbaumer L, Kapfhammer JP. P/Q-type and T-type calcium channels, but not type 3 transient receptor potential cation channels, are involved in inhibition of dendritic growth after chronic metabotropic glutamate receptor type 1 and protein kinase C activation in cerebellar Purkinje cells. The European Journal of Neuroscience. 35: 20-33. PMID 22188405 DOI: 10.1111/j.1460-9568.2011.07942.x  1
2012 Phelan KD, Mock MM, Kretz O, Shwe UT, Kozhemyakin M, Greenfield LJ, Dietrich A, Birnbaumer L, Freichel M, Flockerzi V, Zheng F. Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration. Molecular Pharmacology. 81: 384-92. PMID 22144671 DOI: 10.1124/mol.111.075341  1
2012 Shi J, Ju M, Abramowitz J, Large WA, Birnbaumer L, Albert AP. TRPC1 proteins confer PKC and phosphoinositol activation on native heteromeric TRPC1/C5 channels in vascular smooth muscle: comparative study of wild-type and TRPC1-/- mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 409-19. PMID 21968068 DOI: 10.1096/fj.11-185611  1
2011 Klaiber M, Dankworth B, Kruse M, Hartmann M, Nikolaev VO, Yang RB, Völker K, Gassner B, Oberwinkler H, Feil R, Freichel M, Groschner K, Skryabin BV, Frantz S, Birnbaumer L, et al. A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide. Proceedings of the National Academy of Sciences of the United States of America. 108: 18500-5. PMID 22027011 DOI: 10.1073/pnas.1103300108  1
2011 Young A, Jiang M, Wang Y, Ahmedli NB, Ramirez J, Reese BE, Birnbaumer L, Farber DB. Specific interaction of Gαi3 with the Oa1 G-protein coupled receptor controls the size and density of melanosomes in retinal pigment epithelium. Plos One. 6: e24376. PMID 21931697 DOI: 10.1371/journal.pone.0024376  1
2011 Ma X, Cheng KT, Wong CO, O'Neil RG, Birnbaumer L, Ambudkar IS, Yao X. Heteromeric TRPV4-C1 channels contribute to store-operated Ca(2+) entry in vascular endothelial cells. Cell Calcium. 50: 502-9. PMID 21930300 DOI: 10.1016/j.ceca.2011.08.006  1
2011 Chamero P, Katsoulidou V, Hendrix P, Bufe B, Roberts R, Matsunami H, Abramowitz J, Birnbaumer L, Zufall F, Leinders-Zufall T. G protein G(alpha)o is essential for vomeronasal function and aggressive behavior in mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 12898-903. PMID 21768373 DOI: 10.1073/pnas.1107770108  1
2011 Ding Y, Winters A, Ding M, Graham S, Akopova I, Muallem S, Wang Y, Hong JH, Gryczynski Z, Yang SH, Birnbaumer L, Ma R. Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone. The Journal of Biological Chemistry. 286: 31799-809. PMID 21768109 DOI: 10.1074/jbc.M111.248344  1
2011 Tano JY, Smedlund K, Lee R, Abramowitz J, Birnbaumer L, Vazquez G. Impairment of survival signaling and efferocytosis in TRPC3-deficient macrophages. Biochemical and Biophysical Research Communications. 410: 643-7. PMID 21684255 DOI: 10.1016/j.bbrc.2011.06.045  1
2011 Marom M, Birnbaumer L, Atlas D. Membrane depolarization combined with Gq-activated G-protein-coupled receptors induce transient receptor potential channel 1 (TRPC1)- dependent potentiation of catecholamine release. Neuroscience. 189: 132-45. PMID 21621591 DOI: 10.1016/j.neuroscience.2011.05.007  1
2011 Colaneri A, Staffa N, Fargo DC, Gao Y, Wang T, Peddada SD, Birnbaumer L. Expanded methyl-sensitive cut counting reveals hypomethylation as an epigenetic state that highlights functional sequences of the genome. Proceedings of the National Academy of Sciences of the United States of America. 108: 9715-20. PMID 21602498 DOI: 10.1073/pnas.1105713108  1
2011 Kim MS, Lee KP, Yang D, Shin DM, Abramowitz J, Kiyonaka S, Birnbaumer L, Mori Y, Muallem S. Genetic and pharmacologic inhibition of the Ca2+ influx channel TRPC3 protects secretory epithelia from Ca2+-dependent toxicity. Gastroenterology. 140: 2107-15, 2115.e1-4. PMID 21354153 DOI: 10.1053/j.gastro.2011.02.052  1
2011 Perez-Leighton CE, Schmidt TM, Abramowitz J, Birnbaumer L, Kofuji P. Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC subunits. The European Journal of Neuroscience. 33: 856-67. PMID 21261756 DOI: 10.1111/j.1460-9568.2010.07583.x  1
2011 Fan H, Li P, Zingarelli B, Borg K, Halushka PV, Birnbaumer L, Cook JA. Heterotrimeric Gα(i) proteins are regulated by lipopolysaccharide and are anti-inflammatory in endotoxemia and polymicrobial sepsis. Biochimica Et Biophysica Acta. 1813: 466-72. PMID 21255617 DOI: 10.1016/j.bbamcr.2011.01.012  1
2011 Wang Y, Park S, Bajpayee NS, Nagaoka Y, Boulay G, Birnbaumer L, Jiang M. Augmented glucose-induced insulin release in mice lacking G(o2), but not G(o1) or G(i) proteins. Proceedings of the National Academy of Sciences of the United States of America. 108: 1693-8. PMID 21220323 DOI: 10.1073/pnas.1018903108  1
2011 Hong JH, Li Q, Kim MS, Shin DM, Feske S, Birnbaumer L, Cheng KT, Ambudkar IS, Muallem S. Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells. Traffic (Copenhagen, Denmark). 12: 232-45. PMID 21054717 DOI: 10.1111/j.1600-0854.2010.01138.x  1
2010 Okawa H, Pahlberg J, Rieke F, Birnbaumer L, Sampath AP. Coordinated control of sensitivity by two splice variants of Gα(o) in retinal ON bipolar cells. The Journal of General Physiology. 136: 443-54. PMID 20837674 DOI: 10.1085/jgp.201010477  1
2010 Birnbaumer L, Zurita AR. On the roles of Mg in the activation of G proteins. Journal of Receptor and Signal Transduction Research. 30: 372-5. PMID 20731539 DOI: 10.3109/10799893.2010.508165  1
2010 Zhao A, Ohara-Imaizumi M, Brissova M, Benninger RK, Xu Y, Hao Y, Abramowitz J, Boulay G, Powers AC, Piston D, Jiang M, Nagamatsu S, Birnbaumer L, Gu G. Gαo represses insulin secretion by reducing vesicular docking in pancreatic beta-cells. Diabetes. 59: 2522-9. PMID 20622165 DOI: 10.2337/db09-1719  1
2010 Zuberi Z, Nobles M, Sebastian S, Dyson A, Lim SY, Breckenridge R, Birnbaumer L, Tinker A. Absence of the inhibitory G-protein Galphai2 predisposes to ventricular cardiac arrhythmia. Circulation. Arrhythmia and Electrophysiology. 3: 391-400. PMID 20495013 DOI: 10.1161/CIRCEP.109.894329  1
2010 Zurita A, Zhang Y, Pedersen L, Darden T, Birnbaumer L. Obligatory role in GTP hydrolysis for the amide carbonyl oxygen of the Mg(2+)-coordinating Thr of regulatory GTPases. Proceedings of the National Academy of Sciences of the United States of America. 107: 9596-601. PMID 20457940 DOI: 10.1073/pnas.1004803107  1
2010 Klaiber M, Kruse M, Völker K, Schröter J, Feil R, Freichel M, Gerling A, Feil S, Dietrich A, Londoño JE, Baba HA, Abramowitz J, Birnbaumer L, Penninger JM, Pongs O, et al. Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2. Basic Research in Cardiology. 105: 583-95. PMID 20352235 DOI: 10.1007/s00395-010-0098-z  1
2010 Phan PA, Tadros SF, Kim Y, Birnbaumer L, Housley GD. Developmental regulation of TRPC3 ion channel expression in the mouse cochlea. Histochemistry and Cell Biology. 133: 437-48. PMID 20229053 DOI: 10.1007/s00418-010-0686-x  1
2010 Li Y, Birnbaumer L, Teng CT. Regulation of ERRalpha gene expression by estrogen receptor agonists and antagonists in SKBR3 breast cancer cells: differential molecular mechanisms mediated by g protein-coupled receptor GPR30/GPER-1. Molecular Endocrinology (Baltimore, Md.). 24: 969-80. PMID 20211987 DOI: 10.1210/me.2009-0148  1
2010 Tadros SF, Kim Y, Phan PA, Birnbaumer L, Housley GD. TRPC3 ion channel subunit immunolocalization in the cochlea. Histochemistry and Cell Biology. 133: 137-47. PMID 19882163 DOI: 10.1007/s00418-009-0653-6  1
2010 Zanou N, Shapovalov G, Louis M, Tajeddine N, Gallo C, Van Schoor M, Anguish I, Cao ML, Schakman O, Dietrich A, Lebacq J, Ruegg U, Roulet E, Birnbaumer L, Gailly P. Role of TRPC1 channel in skeletal muscle function. American Journal of Physiology. Cell Physiology. 298: C149-62. PMID 19846750 DOI: 10.1152/ajpcell.00241.2009  1
2010 Birnbaumer L. Signal transduction by G proteins. basic principles, molecular diversity, and structural basis of their actions Handbook of Cell Signaling, 2/E. 2: 1597-1614. DOI: 10.1016/B978-0-12-374145-5.00197-2  1
2010 Albarrán-Juárez J, Gilsbach R, Piekorz R, Pexa K, Beetz N, Schneider J, Nürnberg B, Birnbaumer L, Birnbaumer HL. Correction to "modulation of α2-adrenoceptor functions by heterotrimeric Gαi protein isoforms" (The Journal of Pharmacology and Experimental Therapeutics (2009) 331, (35-34)) Journal of Pharmacology and Experimental Therapeutics. 333: 351.  1
2009 Boknik P, Grote-Wessels S, Barteska G, Jiang M, Müller FU, Schmitz W, Neumann J, Birnbaumer L. Genetic disruption of G proteins, G(i2)alpha or G(o)alpha, does not abolish inotropic and chronotropic effects of stimulating muscarinic cholinoceptors in atrium. British Journal of Pharmacology. 158: 1557-64. PMID 19906118 DOI: 10.1111/j.1476-5381.2009.00441.x  1
2009 Seth M, Zhang ZS, Mao L, Graham V, Burch J, Stiber J, Tsiokas L, Winn M, Abramowitz J, Rockman HA, Birnbaumer L, Rosenberg P. TRPC1 channels are critical for hypertrophic signaling in the heart. Circulation Research. 105: 1023-30. PMID 19797170 DOI: 10.1161/CIRCRESAHA.109.206581  1
2009 Edwards RA, Witherspoon M, Wang K, Afrasiabi K, Pham T, Birnbaumer L, Lipkin SM. Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer. Cancer Research. 69: 6423-9. PMID 19638594 DOI: 10.1158/0008-5472.CAN-09-1285  1
2009 Kim MS, Hong JH, Li Q, Shin DM, Abramowitz J, Birnbaumer L, Muallem S. Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis. Gastroenterology. 137: 1509-17. PMID 19622358 DOI: 10.1053/j.gastro.2009.07.042  1
2009 Tsvilovskyy VV, Zholos AV, Aberle T, Philipp SE, Dietrich A, Zhu MX, Birnbaumer L, Freichel M, Flockerzi V. Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo. Gastroenterology. 137: 1415-24. PMID 19549525 DOI: 10.1053/j.gastro.2009.06.046  1
2009 Cao C, Huang X, Han Y, Wan Y, Birnbaumer L, Feng GS, Marshall J, Jiang M, Chu WM. Galpha(i1) and Galpha(i3) are required for epidermal growth factor-mediated activation of the Akt-mTORC1 pathway. Science Signaling. 2: ra17. PMID 19401591 DOI: 10.1126/scisignal.2000118  1
2009 Birnbaumer L. The TRPC class of ion channels: a critical review of their roles in slow, sustained increases in intracellular Ca(2+) concentrations. Annual Review of Pharmacology and Toxicology. 49: 395-426. PMID 19281310 DOI: 10.1146/annurev.pharmtox.48.113006.094928  1
2009 Liao Y, Plummer NW, George MD, Abramowitz J, Zhu MX, Birnbaumer L. A role for Orai in TRPC-mediated Ca2+ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca2+ entry. Proceedings of the National Academy of Sciences of the United States of America. 106: 3202-6. PMID 19221033 DOI: 10.1073/pnas.0813346106  1
2009 Abramowitz J, Birnbaumer L. Physiology and pathophysiology of canonical transient receptor potential channels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 297-328. PMID 18940894 DOI: 10.1096/fj.08-119495  1
2008 Taranova AG, Maldonado D, Vachon CM, Jacobsen EA, Abdala-Valencia H, McGarry MP, Ochkur SI, Protheroe CA, Doyle A, Grant CS, Cook-Mills J, Birnbaumer L, Lee NA, Lee JJ. Allergic pulmonary inflammation promotes the recruitment of circulating tumor cells to the lung. Cancer Research. 68: 8582-9. PMID 18922934 DOI: 10.1158/0008-5472.CAN-08-1673  1
2008 Zuberi Z, Birnbaumer L, Tinker A. The role of inhibitory heterotrimeric G proteins in the control of in vivo heart rate dynamics. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R1822-30. PMID 18832081 DOI: 10.1152/ajpregu.90625.2008  1
2008 Hartmann J, Dragicevic E, Adelsberger H, Henning HA, Sumser M, Abramowitz J, Blum R, Dietrich A, Freichel M, Flockerzi V, Birnbaumer L, Konnerth A. TRPC3 channels are required for synaptic transmission and motor coordination. Neuron. 59: 392-8. PMID 18701065 DOI: 10.1016/j.neuron.2008.06.009  1
2008 Brunk I, Blex C, Sanchis-Segura C, Sternberg J, Perreau-Lenz S, Bilbao A, Hörtnagl H, Baron J, Juranek J, Laube G, Birnbaumer L, Spanagel R, Ahnert-Hilger G. Deletion of Go2alpha abolishes cocaine-induced behavioral sensitization by disturbing the striatal dopamine system. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3736-46. PMID 18606864 DOI: 10.1096/fj.08-111245  1
2008 Jin YZ, Thompson BD, Zhou ZY, Fu Y, Birnbaumer L, Wu MX. Reciprocal function of Galphai2 and Galphai3 in graft-versus-host disease. European Journal of Immunology. 38: 1988-98. PMID 18521956 DOI: 10.1002/eji.200737738  1
2008 Chaudhuri P, Colles SM, Bhat M, Van Wagoner DR, Birnbaumer L, Graham LM. Elucidation of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement. Molecular Biology of the Cell. 19: 3203-11. PMID 18495872 DOI: 10.1091/mbc.E07-08-0765  1
2008 Young A, Powelson EB, Whitney IE, Raven MA, Nusinowitz S, Jiang M, Birnbaumer L, Reese BE, Farber DB. Involvement of OA1, an intracellular GPCR, and G alpha i3, its binding protein, in melanosomal biogenesis and optic pathway formation. Investigative Ophthalmology & Visual Science. 49: 3245-52. PMID 18378571 DOI: 10.1167/iovs.08-1806  1
2008 Edwards RA, Wang K, Davis JS, Birnbaumer L. Role for epithelial dysregulation in early-onset colitis-associated colon cancer in Gi2-alpha-/- mice. Inflammatory Bowel Diseases. 14: 898-907. PMID 18340649 DOI: 10.1002/ibd.20414  1
2008 Liao Y, Erxleben C, Abramowitz J, Flockerzi V, Zhu MX, Armstrong DL, Birnbaumer L. Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels. Proceedings of the National Academy of Sciences of the United States of America. 105: 2895-900. PMID 18287061 DOI: 10.1073/pnas.0712288105  1
2008 Zurita AR, Birnbaumer L. The same mutation in Gsalpha and transducin alpha reveals behavioral differences between these highly homologous G protein alpha-subunits. Proceedings of the National Academy of Sciences of the United States of America. 105: 2363-8. PMID 18258741 DOI: 10.1073/pnas.0712261105  1
2008 Foller M, Kasinathan RS, Koka S, Lang C, Shumilina E, Birnbaumer L, Lang F, Huber SM. TRPC6 contributes to the Ca(2+) leak of human erythrocytes. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 21: 183-92. PMID 18209485 DOI: 10.1159/000113760  1
2008 Cuthbertson BJ, Liao Y, Birnbaumer L, Blackshear PJ. Characterization of zfs1 as an mRNA-binding and -destabilizing protein in Schizosaccharomyces pombe. The Journal of Biological Chemistry. 283: 2586-94. PMID 18042546 DOI: 10.1074/jbc.M707154200  1
2007 Liu X, Cheng KT, Bandyopadhyay BC, Pani B, Dietrich A, Paria BC, Swaim WD, Beech D, Yildrim E, Singh BB, Birnbaumer L, Ambudkar IS. Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 17542-7. PMID 17956991 DOI: 10.1073/pnas.0701254104  1
2007 Dietrich A, Kalwa H, Storch U, Mederos y Schnitzler M, Salanova B, Pinkenburg O, Dubrovska G, Essin K, Gollasch M, Birnbaumer L, Gudermann T. Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1. PflüGers Archiv : European Journal of Physiology. 455: 465-77. PMID 17647013 DOI: 10.1007/s00424-007-0314-3  1
2007 Fan H, Williams DL, Zingarelli B, Breuel KF, Teti G, Tempel GE, Spicher K, Boulay G, Birnbaumer L, Halushka PV, Cook JA. Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in macrophages by Galpha(i) proteins. Immunology. 122: 116-23. PMID 17484771 DOI: 10.1111/j.1365-2567.2007.02619.x  1
2007 Liao Y, Erxleben C, Yildirim E, Abramowitz J, Armstrong DL, Birnbaumer L. Orai proteins interact with TRPC channels and confer responsiveness to store depletion. Proceedings of the National Academy of Sciences of the United States of America. 104: 4682-7. PMID 17360584 DOI: 10.1073/pnas.0611692104  1
2007 Pero RS, Borchers MT, Spicher K, Ochkur SI, Sikora L, Rao SP, Abdala-Valencia H, O'Neill KR, Shen H, McGarry MP, Lee NA, Cook-Mills JM, Sriramarao P, Simon MI, Birnbaumer L, et al. Galphai2-mediated signaling events in the endothelium are involved in controlling leukocyte extravasation. Proceedings of the National Academy of Sciences of the United States of America. 104: 4371-6. PMID 17360531 DOI: 10.1073/pnas.0700185104  1
2007 Gohla A, Klement K, Piekorz RP, Pexa K, vom Dahl S, Spicher K, Dreval V, Häussinger D, Birnbaumer L, Nürnberg B. An obligatory requirement for the heterotrimeric G protein Gi3 in the antiautophagic action of insulin in the liver. Proceedings of the National Academy of Sciences of the United States of America. 104: 3003-8. PMID 17296938 DOI: 10.1073/pnas.0611434104  1
2007 Thompson BD, Jin Y, Wu KH, Colvin RA, Luster AD, Birnbaumer L, Wu MX. Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling. The Journal of Biological Chemistry. 282: 9547-55. PMID 17289675 DOI: 10.1074/jbc.M610931200  1
2007 Birnbaumer L. Expansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimers. Biochimica Et Biophysica Acta. 1768: 772-93. PMID 17258171 DOI: 10.1016/j.bbamem.2006.12.002  1
2007 Padigel UM, Stein L, Redding K, Lee JJ, Nolan TJ, Schad GA, Birnbaumer L, Abraham D. Signaling through Galphai2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice. Journal of Leukocyte Biology. 81: 1120-6. PMID 17242370 DOI: 10.1189/jlb.1106695  1
2007 Abramowitz J, Birnbaumer L. Know thy neighbor: a survey of diseases and complex syndromes that map to chromosomal regions encoding TRP channels. Handbook of Experimental Pharmacology. 379-408. PMID 17225326 DOI: 10.1007/978-3-540-34891-7_23  1
2007 Yildirim E, Birnbaumer L. TRPC2: molecular biology and functional importance. Handbook of Experimental Pharmacology. 53-75. PMID 17217050 DOI: 10.1007/978-3-540-34891-7_3  1
2007 Birnbaumer L. The discovery of signal transduction by G proteins: a personal account and an overview of the initial findings and contributions that led to our present understanding. Biochimica Et Biophysica Acta. 1768: 756-71. PMID 17141178 DOI: 10.1016/j.bbamem.2006.09.027  1
2006 Ghil S, Choi JM, Kim SS, Lee YD, Liao Y, Birnbaumer L, Suh-Kim H. Compartmentalization of protein kinase A signaling by the heterotrimeric G protein Go. Proceedings of the National Academy of Sciences of the United States of America. 103: 19158-63. PMID 17148597 DOI: 10.1073/pnas.0609392103  1
2006 Fan H, Williams DL, Zingarelli B, Breuel KF, Teti G, Tempel GE, Spicher K, Boulay G, Birnbaumer L, Halushka PV, Cook JA. Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in splenocytes by Galphai proteins. Biochimica Et Biophysica Acta. 1763: 1051-8. PMID 16962188 DOI: 10.1016/j.bbamcr.2006.08.003  1
2006 Erxleben C, Liao Y, Gentile S, Chin D, Gomez-Alegria C, Mori Y, Birnbaumer L, Armstrong DL. Cyclosporin and Timothy syndrome increase mode 2 gating of CaV1.2 calcium channels through aberrant phosphorylation of S6 helices. Proceedings of the National Academy of Sciences of the United States of America. 103: 3932-7. PMID 16537462 DOI: 10.1073/pnas.0511322103  1
2006 Kawasaki BT, Liao Y, Birnbaumer L. Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor- and store-operated Ca2+ entry channels. Proceedings of the National Academy of Sciences of the United States of America. 103: 335-40. PMID 16407161 DOI: 10.1073/pnas.0508030102  1
2005 Dietrich A, Mederos Y Schnitzler M, Gollasch M, Gross V, Storch U, Dubrovska G, Obst M, Yildirim E, Salanova B, Kalwa H, Essin K, Pinkenburg O, Luft FC, Gudermann T, Birnbaumer L. Increased vascular smooth muscle contractility in TRPC6-/- mice. Molecular and Cellular Biology. 25: 6980-9. PMID 16055711 DOI: 10.1128/MCB.25.16.6980-6989.2005  1
2005 Winter S, Brunk I, Walther DJ, Höltje M, Jiang M, Peter JU, Takamori S, Jahn R, Birnbaumer L, Ahnert-Hilger G. Galphao2 regulates vesicular glutamate transporter activity by changing its chloride dependence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4672-80. PMID 15872115 DOI: 10.1523/JNEUROSCI.0549-05.2005  1
2005 Fan H, Zingarelli B, Peck OM, Teti G, Tempel GE, Halushka PV, Spicher K, Boulay G, Birnbaumer L, Cook JA. Lipopolysaccharide- and gram-positive bacteria-induced cellular inflammatory responses: role of heterotrimeric Galpha(i) proteins. American Journal of Physiology. Cell Physiology. 289: C293-301. PMID 15788486 DOI: 10.1152/ajpcell.00394.2004  0.4
2005 Skokowa J, Ali SR, Felda O, Kumar V, Konrad S, Shushakova N, Schmidt RE, Piekorz RP, Nürnberg B, Spicher K, Birnbaumer L, Zwirner J, Claassens JW, Verbeek JS, van Rooijen N, et al. Macrophages induce the inflammatory response in the pulmonary Arthus reaction through G alpha i2 activation that controls C5aR and Fc receptor cooperation. Journal of Immunology (Baltimore, Md. : 1950). 174: 3041-50. PMID 15728518  1
2005 Yildirim E, Kawasaki BT, Birnbaumer L. Molecular cloning of TRPC3a, an N-terminally extended, store-operated variant of the human C3 transient receptor potential channel. Proceedings of the National Academy of Sciences of the United States of America. 102: 3307-11. PMID 15728370 DOI: 10.1073/pnas.0409908102  1
2005 Wei B, Velazquez P, Turovskaya O, Spricher K, Aranda R, Kronenberg M, Birnbaumer L, Braun J. Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets. Proceedings of the National Academy of Sciences of the United States of America. 102: 2010-5. PMID 15684084 DOI: 10.1073/pnas.0409449102  1
2004 Abramowitz J, Grenet D, Birnbaumer M, Torres HN, Birnbaumer L. XLalphas, the extra-long form of the alpha-subunit of the Gs G protein, is significantly longer than suspected, and so is its companion Alex. Proceedings of the National Academy of Sciences of the United States of America. 101: 8366-71. PMID 15148396 DOI: 10.1073/pnas.0308758101  1
2004 Pineda VV, Athos JI, Wang H, Celver J, Ippolito D, Boulay G, Birnbaumer L, Storm DR. Removal of G(ialpha1) constraints on adenylyl cyclase in the hippocampus enhances LTP and impairs memory formation. Neuron. 41: 153-63. PMID 14715142 DOI: 10.1016/S0896-6273(03)00813-4  1
2004 D'Angelo MA, Sanguineti S, Reece JM, Birnbaumer L, Torres HN, Flawiá MM. Identification, characterization and subcellular localization of TcPDE1, a novel cAMP-specific phosphodiesterase from Trypanosoma cruzi. The Biochemical Journal. 378: 63-72. PMID 14556647 DOI: 10.1042/BJ20031147  1
2003 Foerster K, Groner F, Matthes J, Koch WJ, Birnbaumer L, Herzig S. Cardioprotection specific for the G protein Gi2 in chronic adrenergic signaling through beta 2-adrenoceptors. Proceedings of the National Academy of Sciences of the United States of America. 100: 14475-80. PMID 14612574 DOI: 10.1073/pnas.1936026100  1
2003 Huang TT, Zong Y, Dalwadi H, Chung C, Miceli MC, Spicher K, Birnbaumer L, Braun J, Aranda R. TCR-mediated hyper-responsiveness of autoimmune Galphai2(-/-) mice is an intrinsic naïve CD4(+) T cell disorder selective for the Galphai2 subunit. International Immunology. 15: 1359-67. PMID 14565934 DOI: 10.1093/intimm/dxg135  1
2003 Pio BS, Byrne FR, Aranda R, Boulay G, Spicher K, Song MH, Birnbaumer L, Phelps ME, Czernin J, Silverman DH. Noninvasive quantification of bowel inflammation through positron emission tomography imaging of 2-deoxy-2-[18F]fluoro-D-glucose-labeled white blood cells. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 5: 271-7. PMID 14499142 DOI: 10.1016/S1536-1632(03)00103-3  1
2003 Birnbaumer L, Yildirim E, Abramowitz J, Yidirim E. A comparison of the genes coding for canonical TRP channels and their M, V and P relatives. Cell Calcium. 33: 419-32. PMID 12765687 DOI: 10.1016/S0143-4160(03)00068-X  1
2003 Kim BJ, Ghil SH, Kim MJ, Yun Park S, Kim DS, Hwan Kim S, Chin H, Birnbaumer L, Jiang M, Hong SY, Suh-Kim H, Lee YD. Modulation of the N-type calcium channel gene expression by the alpha subunit of Go. Brain Research. Molecular Brain Research. 112: 95-102. PMID 12670707 DOI: 10.1016/S0169-328X(03)00053-6  1
2003 Trebak M, St J Bird G, McKay RR, Birnbaumer L, Putney JW. Signaling mechanism for receptor-activated canonical transient receptor potential 3 (TRPC3) channels. The Journal of Biological Chemistry. 278: 16244-52. PMID 12606542 DOI: 10.1074/jbc.M300544200  1
2003 Yildirim E, Dietrich A, Birnbaumer L. The mouse C-type transient receptor potential 2 (TRPC2) channel: alternative splicing and calmodulin binding to its N terminus. Proceedings of the National Academy of Sciences of the United States of America. 100: 2220-5. PMID 12601176 DOI: 10.1073/pnas.0438036100  1
2003 Erxleben C, Gomez-Alegria C, Darden T, Mori Y, Birnbaumer L, Armstrong DL. Modulation of cardiac Ca(V)1.2 channels by dihydropyridine and phosphatase inhibitor requires Ser-1142 in the domain III pore loop. Proceedings of the National Academy of Sciences of the United States of America. 100: 2929-34. PMID 12601159 DOI: 10.1073/pnas.2628046100  1
2003 Birnbaumer L. Signal Transduction by G Proteins-Basic Principles, Molecular Diversity, and Structural Basis of Their Actions Handbook of Cell Signaling. 2: 557-569. DOI: 10.1016/B978-012124546-7/50574-X  1
2002 Ohman L, Franzén L, Rudolph U, Birnbaumer L, Hörnquist EH. Regression of Peyer's patches in G alpha i2 deficient mice prior to colitis is associated with reduced expression of Bcl-2 and increased apoptosis. Gut. 51: 392-7. PMID 12171962 DOI: 10.1136/gut.51.3.392  1
2002 Chu X, Cheung JY, Barber DL, Birnbaumer L, Rothblum LI, Conrad K, Abrasonis V, Chan YM, Stahl R, Carey DJ, Miller BA. Erythropoietin modulates calcium influx through TRPC2. The Journal of Biological Chemistry. 277: 34375-82. PMID 12167663 DOI: 10.1074/jbc.M205541200  1
2002 Birnbaumer L. TRPC4 knockout mice: the coming of age of TRP channels as gates of calcium entry responsible for cellular responses. Circulation Research. 91: 1-3. PMID 12114313 DOI: 10.1161/01.RES.0000026600.67226.92  1
2002 Dhingra A, Jiang M, Wang TL, Lyubarsky A, Savchenko A, Bar-Yehuda T, Sterling P, Birnbaumer L, Vardi N. Light response of retinal ON bipolar cells requires a specific splice variant of Galpha(o). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4878-84. PMID 12077185  1
2002 Montell C, Birnbaumer L, Flockerzi V. The TRP channels, a remarkably functional family. Cell. 108: 595-8. PMID 11893331 DOI: 10.1016/S0092-8674(02)00670-0  1
2002 Mukherjee S, Gurevich VV, Preninger A, Hamm HE, Bader MF, Fazleabas AT, Birnbaumer L, Hunzicker-Dunn M. Aspartic acid 564 in the third cytoplasmic loop of the luteinizing hormone/choriogonadotropin receptor is crucial for phosphorylation-independent interaction with arrestin2. The Journal of Biological Chemistry. 277: 17916-27. PMID 11867621 DOI: 10.1074/jbc.M110479200  1
2002 Montell C, Birnbaumer L, Flockerzi V, Bindels RJ, Bruford EA, Caterina MJ, Clapham DE, Harteneck C, Heller S, Julius D, Kojima I, Mori Y, Penner R, Prawitt D, Scharenberg AM, et al. A unified nomenclature for the superfamily of TRP cation channels. Molecular Cell. 9: 229-31. PMID 11864597 DOI: 10.1016/S1097-2765(02)00448-3  1
2002 Jiang M, Spicher K, Boulay G, Martín-Requero A, Dye CA, Rudolph U, Birnbaumer L. Mouse gene knockout and knockin strategies in application to alpha subunits of Gi/Go family of G proteins. Methods in Enzymology. 344: 277-98. PMID 11771389 DOI: 10.1016/S0076-6879(02)44721-0  1
2002 Hunzicker-Dunn M, Birnbaumer L. Cell-free membrane desensitization assay for G protein-coupled receptors. Methods in Enzymology. 343: 394-404. PMID 11665580 DOI: 10.1016/S0076-6879(02)43147-3  1
2001 Uhlig HH, Hultgren Hörnquist E, Ohman Bache L, Rudolph U, Birnbaumer L, Mothes T. Antibody response to dietary and autoantigens in G alpha i2-deficient mice. European Journal of Gastroenterology & Hepatology. 13: 1421-9. PMID 11742190 DOI: 10.1097/00042737-200112000-00005  1
2001 Singh BB, Zheng C, Liu X, Lockwich T, Liao D, Zhu MX, Birnbaumer L, Ambudkar IS. Trp1-dependent enhancement of salivary gland fluid secretion: role of store-operated calcium entry. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1652-4. PMID 11427516  1
2001 Jungnickel MK, Marrero H, Birnbaumer L, Lémos JR, Florman HM. Trp2 regulates entry of Ca2+ into mouse sperm triggered by egg ZP3. Nature Cell Biology. 3: 499-502. PMID 11331878 DOI: 10.1038/35074570  1
2001 Chen F, Spicher K, Jiang M, Birnbaumer L, Wetzel GT. Lack of muscarinic regulation of Ca(2+) channels in G(i2)alpha gene knockout mouse hearts. American Journal of Physiology. Heart and Circulatory Physiology. 280: H1989-95. PMID 11299198  1
2001 Tang J, Lin Y, Zhang Z, Tikunova S, Birnbaumer L, Zhu MX. Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels. The Journal of Biological Chemistry. 276: 21303-10. PMID 11290752 DOI: 10.1074/jbc.M102316200  1
2001 Jiang M, Spicher K, Boulay G, Wang Y, Birnbaumer L. Most central nervous system D2 dopamine receptors are coupled to their effectors by Go. Proceedings of the National Academy of Sciences of the United States of America. 98: 3577-82. PMID 11248120 DOI: 10.1073/pnas.051632598  1
2001 Zhang Z, Tang J, Tikunova S, Johnson JD, Chen Z, Qin N, Dietrich A, Stefani E, Birnbaumer L, Zhu MX. Activation of Trp3 by inositol 1,4,5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain. Proceedings of the National Academy of Sciences of the United States of America. 98: 3168-73. PMID 11248050 DOI: 10.1073/pnas.051632698  1
2000 Dhingra A, Lyubarsky A, Jiang M, Pugh EN, Birnbaumer L, Sterling P, Vardi N. The light response of ON bipolar neurons requires G[alpha]o. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 9053-8. PMID 11124982  1
2000 Birnbaumer L, Boulay G, Brown D, Jiang M, Dietrich A, Mikoshiba K, Zhu X, Qin N. Mechanism of capacitative Ca2+ entry (CCE): interaction between IP3 receptor and TRP links the internal calcium storage compartment to plasma membrane CCE channels. Recent Progress in Hormone Research. 55: 127-61; discussion 1. PMID 11036936  1
2000 Birnbaumer L. Citation for the 2000 Distinguished Educator Award of The Endocrine Society to Dr. Stanley Korenman. Endocrine Reviews. 21: 453-4. PMID 10950168  1
2000 Platano D, Qin N, Noceti F, Birnbaumer L, Stefani E, Olcese R. Expression of the alpha(2)delta subunit interferes with prepulse facilitation in cardiac L-type calcium channels. Biophysical Journal. 78: 2959-72. PMID 10827975 DOI: 10.1016/S0006-3495(00)76835-4  1
2000 Ertel EA, Campbell KP, Harpold MM, Hofmann F, Mori Y, Perez-Reyes E, Schwartz A, Snutch TP, Tanabe T, Birnbaumer L, Tsien RW, Catterall WA. Nomenclature of voltage-gated calcium channels. Neuron. 25: 533-5. PMID 10774722  1
2000 Ma HT, Patterson RL, van Rossum DB, Birnbaumer L, Mikoshiba K, Gill DL. Requirement of the inositol trisphosphate receptor for activation of store-operated Ca2+ channels. Science (New York, N.Y.). 287: 1647-51. PMID 10698739 DOI: 10.1126/science.287.5458.1647  1
1999 Boulay G, Brown DM, Qin N, Jiang M, Dietrich A, Zhu MX, Chen Z, Birnbaumer M, Mikoshiba K, Birnbaumer L. Modulation of Ca(2+) entry by polypeptides of the inositol 1,4, 5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca(2+) entry. Proceedings of the National Academy of Sciences of the United States of America. 96: 14955-60. PMID 10611319 DOI: 10.1073/pnas.96.26.14955  1
1999 Costantin JL, Qin N, Waxham MN, Birnbaumer L, Stefani E. Complete reversal of run-down in rabbit cardiac Ca2+ channels by patch-cramming in Xenopus oocytes; partial reversal by protein kinase A. PflüGers Archiv : European Journal of Physiology. 437: 888-94. PMID 10370067 DOI: 10.1007/s004240050859  1
1999 Wang W, O'Connell B, Dykeman R, Sakai T, Delporte C, Swaim W, Zhu X, Birnbaumer L, Ambudkar IS. Cloning of Trp1beta isoform from rat brain: immunodetection and localization of the endogenous Trp1 protein. The American Journal of Physiology. 276: C969-79. PMID 10199829  1
1999 Birnbaumer L. Martin Rodbell (1925-1998). Science (New York, N.Y.). 283: 1656. PMID 10189319  1
1999 Rajagopalan-Gupta RM, Mukherjee S, Zhu X, Ho YK, Hamm H, Birnbaumer M, Birnbaumer L, Hunzicker-Dunn M. Roles of Gi and Gq/11 in mediating desensitization of the luteinizing hormone/choriogonadotropin receptor in porcine ovarian follicular membranes. Endocrinology. 140: 1612-21. PMID 10098495 DOI: 10.1210/endo.140.4.6657  1
1999 Qin N, Olcese R, Bransby M, Lin T, Birnbaumer L. Ca2+-induced inhibition of the cardiac Ca2+ channel depends on calmodulin. Proceedings of the National Academy of Sciences of the United States of America. 96: 2435-8. PMID 10051660 DOI: 10.1073/pnas.96.5.2435  1
1999 Vannier B, Peyton M, Boulay G, Brown D, Qin N, Jiang M, Zhu X, Birnbaumer L. Mouse trp2, the homologue of the human trpc2 pseudogene, encodes mTrp2, a store depletion-activated capacitative Ca2+ entry channel. Proceedings of the National Academy of Sciences of the United States of America. 96: 2060-4. PMID 10051594 DOI: 10.1073/pnas.96.5.2060  1
1998 Qin N, Olcese R, Stefani E, Birnbaumer L. Modulation of human neuronal α-type calcium channel by αδ-subunit. American Journal of Physiology. Cell Physiology. 274: C1324-C1331. PMID 29591061 DOI: 10.1152/ajpcell.1998.274.5.C1324  0.4
1998 Zhu X, Birnbaumer L. Calcium Channels Formed by Mammalian Trp Homologues. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 13: 211-217. PMID 11390792  1
1998 Kiselyov K, Xu X, Mozhayeva G, Kuo T, Pessah I, Mignery G, Zhu X, Birnbaumer L, Muallem S. Functional interaction between InsP3 receptors and store-operated Htrp3 channels. Nature. 396: 478-82. PMID 9853757 DOI: 10.1038/24890  1
1998 Birnbaumer L, Qin N, Olcese R, Tareilus E, Platano D, Costantin J, Stefani E. Structures and functions of calcium channel beta subunits. Journal of Bioenergetics and Biomembranes. 30: 357-75. PMID 9758332 DOI: 10.1023/A:1021989622656  1
1998 Ottolia M, Platano D, Qin N, Noceti F, Birnbaumer M, Toro L, Birnbaumer L, Stefani E, Olcese R. Functional coupling between human E-type Ca2+ channels and mu opioid receptors expressed in Xenopus oocytes. Febs Letters. 427: 96-102. PMID 9613607 DOI: 10.1016/S0014-5793(98)00401-3  1
1998 Qin N, Olcese R, Stefani E, Birnbaumer L. Modulation of human neuronal alpha 1E-type calcium channel by alpha 2 delta-subunit. The American Journal of Physiology. 274: C1324-31. PMID 9612220  1
1998 Qin N, Platano D, Olcese R, Costantin JL, Stefani E, Birnbaumer L. Unique regulatory properties of the type 2a Ca2+ channel beta subunit caused by palmitoylation. Proceedings of the National Academy of Sciences of the United States of America. 95: 4690-5. PMID 9539800 DOI: 10.1073/pnas.95.8.4690  1
1998 Vannier B, Zhu X, Brown D, Birnbaumer L. The membrane topology of human transient receptor potential 3 as inferred from glycosylation-scanning mutagenesis and epitope immunocytochemistry. The Journal of Biological Chemistry. 273: 8675-9. PMID 9535843 DOI: 10.1074/jbc.273.15.8675  1
1998 Costantin JL, Qin N, Zhou J, Platano D, Birnbaumer L, Stefani E. Long lasting facilitation of the rabbit cardiac Ca2+ channel: correlation with the coupling efficiency between charge movement and pore opening. Febs Letters. 423: 213-7. PMID 9512359 DOI: 10.1016/S0014-5793(98)00092-1  1
1998 Jiang M, Gold MS, Boulay G, Spicher K, Peyton M, Brabet P, Srinivasan Y, Rudolph U, Ellison G, Birnbaumer L. Multiple neurological abnormalities in mice deficient in the G protein Go. Proceedings of the National Academy of Sciences of the United States of America. 95: 3269-74. PMID 9501252 DOI: 10.1073/pnas.95.6.3269  1
1998 Hurst RS, Zhu X, Boulay G, Birnbaumer L, Stefani E. Ionic currents underlying HTRP3 mediated agonist-dependent Ca2+ influx in stably transfected HEK293 cells. Febs Letters. 422: 333-8. PMID 9498810 DOI: 10.1016/S0014-5793(98)00035-0  1
1998 Costantin J, Noceti F, Qin N, Wei X, Birnbaumer L, Stefani E. Facilitation by the beta2a subunit of pore openings in cardiac Ca2+ channels. The Journal of Physiology. 507: 93-103. PMID 9490822  1
1998 Zhu X, Jiang M, Birnbaumer L. Receptor-activated Ca2+ influx via human Trp3 stably expressed in human embryonic kidney (HEK)293 cells. Evidence for a non-capacitative Ca2+ entry. The Journal of Biological Chemistry. 273: 133-42. PMID 9417057  0.4
1998 Costantin J, Noceti F, Qin N, Wei X, Birnbaumer L, Stefani E. Facilitation by the β(2a) subunit of pore openings in cardiac Ca2+ channels Journal of Physiology. 507: 93-103. DOI: 10.1111/j.1469-7793.1998.093bu.x  1
1997 Jiang M, Boulay G, Spicher K, Peyton MJ, Brabet P, Birnbaumer L, Rudolph U. Inactivation of the G alpha i2 and G alpha o genes by homologous recombination. Receptors & Channels. 5: 187-92. PMID 9606722  1
1997 Boulay G, Zhu X, Peyton M, Jiang M, Hurst R, Stefani E, Birnbaumer L. Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein. The Journal of Biological Chemistry. 272: 29672-80. PMID 9368034 DOI: 10.1074/jbc.272.47.29672  1
1997 Qin N, Platano D, Olcese R, Stefani E, Birnbaumer L. Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America. 94: 8866-71. PMID 9238069 DOI: 10.1073/pnas.94.16.8866  1
1997 Zhou J, Olcese R, Qin N, Noceti F, Birnbaumer L, Stefani E. Feedback inhibition of Ca2+ channels by Ca2+ depends on a short sequence of the C terminus that does not include the Ca2+ -binding function of a motif with similarity to Ca2+ -binding domains. Proceedings of the National Academy of Sciences of the United States of America. 94: 2301-5. PMID 9122189 DOI: 10.1073/pnas.94.6.2301  1
1997 Tareilus E, Roux M, Qin N, Olcese R, Zhou J, Stefani E, Birnbaumer L. A Xenopus oocyte beta subunit: evidence for a role in the assembly/expression of voltage-gated calcium channels that is separate from its role as a regulatory subunit. Proceedings of the National Academy of Sciences of the United States of America. 94: 1703-8. PMID 9050842 DOI: 10.1073/pnas.94.5.1703  1
1997 Hörnquist CE, Lu X, Rogers-Fani PM, Rudolph U, Shappell S, Birnbaumer L, Harriman GR. G(alpha)i2-deficient mice with colitis exhibit a local increase in memory CD4+ T cells and proinflammatory Th1-type cytokines. Journal of Immunology (Baltimore, Md. : 1950). 158: 1068-77. PMID 9013944  1
1996 Suh-Kim H, Wei X, Klos A, Pan S, Ruth P, Flockerzi V, Hofmann F, Perez-Reyes E, Birnbaumer L. Reconstitution of the skeletal muscle dihydropyridine receptor. Functional interaction among alpha 1, beta, gamma and alpha 2 delta subunits. Receptors & Channels. 4: 217-25. PMID 9065970  1
1996 Wei X, Neely A, Olcese R, Lang W, Stefani E, Birnbaumer L. Increase in Ca2+ channel expression by deletions at the amino terminus of the cardiac alpha 1C subunit. Receptors & Channels. 4: 205-15. PMID 9065969  1
1996 Olcese R, Neely A, Qin N, Wei X, Birnbaumer L, Stefani E. Coupling between charge movement and pore opening in vertebrate neuronal alpha 1E calcium channels. The Journal of Physiology. 497: 675-86. PMID 9003553  1
1996 Birnbaumer L, Zhu X, Jiang M, Boulay G, Peyton M, Vannier B, Brown D, Platano D, Sadeghi H, Stefani E, Birnbaumer M. On the molecular basis and regulation of cellular capacitative calcium entry: roles for Trp proteins. Proceedings of the National Academy of Sciences of the United States of America. 93: 15195-202. PMID 8986787  0.68
1996 Qin N, Olcese R, Zhou J, Cabello OA, Birnbaumer L, Stefani E. Identification of a second region of the beta-subunit involved in regulation of calcium channel inactivation. The American Journal of Physiology. 271: C1539-45. PMID 8944637  1
1996 Suh-Kim H, Wei X, Birnbaumer L. Subunit composition is a major determinant in high affinity binding of a Ca2+ channel blocker. Molecular Pharmacology. 50: 1330-7. PMID 8913365  0.44
1996 Noceti F, Baldelli P, Wei X, Qin N, Toro L, Birnbaumer L, Stefani E. Effective gating charges per channel in voltage-dependent K+ and Ca2+ channels. The Journal of General Physiology. 108: 143-55. PMID 8882860  1
1996 Zhu X, Jiang M, Peyton M, Boulay G, Hurst R, Stefani E, Birnbaumer L. trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry. Cell. 85: 661-71. PMID 8646775  0.4
1996 Rudolph U, Spicher K, Birnbaumer L. Adenylyl cyclase inhibition and altered G protein subunit expression and ADP-ribosylation patterns in tissues and cells from Gi2 alpha-/-mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 3209-14. PMID 8622915  1
1996 Zhu X, Birnbaumer L. G protein subunits and the stimulation of phospholipase C by Gs-and Gi-coupled receptors: Lack of receptor selectivity of Galpha(16) and evidence for a synergic interaction between Gbeta gamma and the alpha subunit of a receptor activated G protein. Proceedings of the National Academy of Sciences of the United States of America. 93: 2827-31. PMID 8610126  0.32
1995 Birnbaumer L, Birnbaumer M. Signal transduction by G proteins: 1994 edition. Journal of Receptor and Signal Transduction Research. 15: 213-52. PMID 8903942 DOI: 10.3109/10799899509045218  0.68
1995 Rudolph U, Finegold MJ, Rich SS, Harriman GR, Srinivasan Y, Brabet P, Bradley A, Birnbaumer L. Gi2 alpha protein deficiency: a model of inflammatory bowel disease. Journal of Clinical Immunology. 15: 101S-105S. PMID 8613481 DOI: 10.1007/BF01540899  1
1995 Day NS, Ge T, Codina J, Birnbaumer L, Vanhoutte PM, Boulanger CM. Gi proteins and the response to 5-hydroxytryptamine in porcine cultured endothelial cells with impaired release of EDRF. British Journal of Pharmacology. 115: 822-7. PMID 8548182  0.52
1995 Neely A, Olcese R, Baldelli P, Wei X, Birnbaumer L, Stefani E. Dual activation of the cardiac Ca2+ channel alpha 1C-subunit and its modulation by the beta-subunit. The American Journal of Physiology. 268: C732-40. PMID 7900777  1
1995 Gudermann T, Birnbaumer M, Birnbaumer L. Homologous desensitization of the murine luteinizing hormone receptor expressed in L cells. Molecular and Cellular Endocrinology. 110: 125-35. PMID 7672443 DOI: 10.1016/0303-7207(95)03538-I  1
1995 Rudolph U, Finegold MJ, Rich SS, Harriman GR, Srinivasan Y, Brabet P, Boulay G, Bradley A, Birnbaumer L. Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice. Nature Genetics. 10: 143-50. PMID 7663509 DOI: 10.1038/ng0695-143  1
1995 Wei X, Pan S, Lang W, Kim H, Schneider T, Perez-Reyes E, Birnbaumer L. Molecular determinants of cardiac Ca2+ channel pharmacology. Subunit requirement for the high affinity and allosteric regulation of dihydropyridine binding. The Journal of Biological Chemistry. 270: 27106-11. PMID 7592963  1
1995 Zhu X, Chu PB, Peyton M, Birnbaumer L. Molecular cloning of a widely expressed human homologue for the Drosophila trp gene. Febs Letters. 373: 193-8. PMID 7589464  0.32
1995 Schneider T, Perez-Reyes E, Nyormoi O, Wei X, Crawford GD, Smith RG, Appel SH, Birnbaumer L. Alpha-1 subunits of voltage gated Ca2+ channels in the mesencephalon x neuroblastoma hybrid cell line MES23.5. Neuroscience. 68: 479-85. PMID 7477958 DOI: 10.1016/0306-4522(95)00147-B  1
1994 Birnbaumer L, Levy FO, Zhu X, Kaumann AJ. Studies on the intrinsic activity (efficacy) of human adrenergic receptors. Co-expression of beta 1 and beta 2 reveals a lower efficacy for the beta 1 receptor. Texas Heart Institute Journal / From the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital. 21: 16-21. PMID 8180506  0.52
1994 Antonelli M, Birnbaumer L, Allende JE, Olate J. Human-Xenopus chimeras of Gs alpha reveal a new region important for its activation of adenylyl cyclase. Febs Letters. 340: 249-54. PMID 8131853 DOI: 10.1016/0014-5793(94)80148-7  1
1994 Shibano T, Codina J, Birnbaumer L, Vanhoutte PM. Pertussis toxin-sensitive G proteins in regenerated endothelial cells of porcine coronary artery. The American Journal of Physiology. 267: H979-81. PMID 8092301  0.52
1994 Neely A, Olcese R, Wei X, Birnbaumer L, Stefani E. Ca(2+)-dependent inactivation of a cloned cardiac Ca2+ channel alpha 1 subunit (alpha 1C) expressed in Xenopus oocytes. Biophysical Journal. 66: 1895-903. PMID 8075326 DOI: 10.1016/S0006-3495(94)80983-X  1
1994 Olcese R, Qin N, Schneider T, Neely A, Wei X, Stefani E, Birnbaumer L. The amino terminus of a calcium channel beta subunit sets rates of channel inactivation independently of the subunit's effect on activation. Neuron. 13: 1433-8. PMID 7993634 DOI: 10.1016/0896-6273(94)90428-6  1
1994 Codina J, Birnbaumer L. Requirement for intramolecular domain interaction in activation of G protein alpha subunit by aluminum fluoride and GDP but not by GTP gamma S. The Journal of Biological Chemistry. 269: 29339-42. PMID 7961906  0.52
1994 Zhu X, Gilbert S, Birnbaumer M, Birnbaumer L. Dual signaling potential is common among Gs-coupled receptors and dependent on receptor density. Molecular Pharmacology. 46: 460-9. PMID 7935326  0.68
1994 Birnbaumer L, Grenet D, Ribeiro-Neto F, Codina J. )Preparation of activated alpha subunits of Gs and Gis: from erythrocyte to activated subunit. Methods in Enzymology. 237: 110-30. PMID 7934989  0.52
1994 Birnbaumer L, Campbell KP, Catterall WA, Harpold MM, Hofmann F, Horne WA, Mori Y, Schwartz A, Snutch TP, Tanabe T. The naming of voltage-gated calcium channels. Neuron. 13: 505-6. PMID 7917287  1
1994 Hu Y, Vaca L, Zhu X, Birnbaumer L, Kunze DL, Schilling WP. Appearance of a novel Ca2+ influx pathway in Sf9 insect cells following expression of the transient receptor potential-like (trpl) protein of Drosophila. Biochemical and Biophysical Research Communications. 201: 1050-6. PMID 7516156 DOI: 10.1006/bbrc.1994.1808  1
1994 Wei X, Neely A, Lacerda AE, Olcese R, Stefani E, Perez-Reyes E, Birnbaumer L. Modification of Ca2+ channel activity by deletions at the carboxyl terminus of the cardiac alpha 1 subunit. The Journal of Biological Chemistry. 269: 1635-40. PMID 7507480  1
1993 Gudermann T, Levy FO, Birnbaumer M, Birnbaumer L, Kaumann AJ. Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor. Molecular Pharmacology. 43: 412-8. PMID 8450834  1
1993 Zhu X, Gudermann T, Birnbaumer M, Birnbaumer L. A luteinizing hormone receptor with a severely truncated cytoplasmic tail (LHR-ct628) desensitizes to the same degree as the full-length receptor. The Journal of Biological Chemistry. 268: 1723-8. PMID 8420950  1
1993 Rosenthal W, Gudermann T, Antaramian A, Seibold A, Lonergan M, Arthus MF, Hendy GN, Birnbaumer L, Bichet DG, Birnbaumer M. Gs-activating receptors: modes of transmembrane signalling and genetic defects. Advances in Second Messenger and Phosphoprotein Research. 28: 47-55. PMID 8398417  1
1993 Blitzer RD, Omri G, De Vivo M, Carty DJ, Premont RT, Codina J, Birnbaumer L, Cotecchia S, Caron MG, Lefkowitz RJ. Coupling of the expressed alpha 1B-adrenergic receptor to the phospholipase C pathway in Xenopus oocytes. The role of Go. The Journal of Biological Chemistry. 268: 7532-7. PMID 8385110  1
1993 Levy FO, Zhu X, Kaumann AJ, Birnbaumer L. Efficacy of beta 1-adrenergic receptors is lower than that of beta 2-adrenergic receptors. Proceedings of the National Academy of Sciences of the United States of America. 90: 10798-802. PMID 8248173  0.52
1993 Scornik FS, Codina J, Birnbaumer L, Toro L. Modulation of coronary smooth muscle KCa channels by Gs alpha independent of phosphorylation by protein kinase A. The American Journal of Physiology. 265: H1460-5. PMID 8238435  1
1993 Neely A, Wei X, Olcese R, Birnbaumer L, Stefani E. Potentiation by the beta subunit of the ratio of the ionic current to the charge movement in the cardiac calcium channel. Science (New York, N.Y.). 262: 575-8. PMID 8211185  1
1993 Castellano A, Wei X, Birnbaumer L, Perez-Reyes E. Cloning and expression of a neuronal calcium channel beta subunit. The Journal of Biological Chemistry. 268: 12359-66. PMID 7685340  1
1993 Castellano A, Wei X, Birnbaumer L, Perez-Reyes E. Cloning and expression of a third calcium channel beta subunit. The Journal of Biological Chemistry. 268: 3450-5. PMID 7679112  1
1992 Levy FO, Gudermann T, Birnbaumer M, Kaumann AJ, Birnbaumer L. Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase. Febs Letters. 296: 201-6. PMID 1733778 DOI: 10.1016/0014-5793(92)80379-U  1
1992 Levy FO, Gudermann T, Perez-Reyes E, Birnbaumer M, Kaumann AJ, Birnbaumer L. Molecular cloning of a human serotonin receptor (S12) with a pharmacological profile resembling that of the 5-HT1D subtype. The Journal of Biological Chemistry. 267: 7553-62. PMID 1559993  1
1992 Graf R, Mattera R, Codina J, Evans T, Ho YK, Estes MK, Birnbaumer L. Studies on the interaction of alpha subunits of GTP-binding proteins with beta gamma dimers. European Journal of Biochemistry / Febs. 210: 609-19. PMID 1459143  0.52
1992 Shibano T, Codina J, Birnbaumer L, Vanhoutte PM. Guanosine 5'-O-(3-thiotriphosphate) causes endothelium-dependent, pertussis toxin-sensitive relaxations in porcine coronary arteries. Biochemical and Biophysical Research Communications. 189: 324-9. PMID 1449486  0.52
1992 Graf R, Codina J, Birnbaumer L. Peptide inhibitors of ADP-ribosylation by pertussis toxin are substrates with affinities comparable to those of the trimeric GTP-binding proteins. Molecular Pharmacology. 42: 760-4. PMID 1435750  0.52
1992 Perez-Reyes E, Castellano A, Kim HS, Bertrand P, Baggstrom E, Lacerda AE, Wei XY, Birnbaumer L. Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel. The Journal of Biological Chemistry. 267: 1792-7. PMID 1370480  1
1992 Yaney GC, Wheeler MB, Wei X, Perez-Reyes E, Birnbaumer L, Boyd AE, Moss LG. Cloning of a novel alpha 1-subunit of the voltage-dependent calcium channel from the beta-cell. Molecular Endocrinology (Baltimore, Md.). 6: 2143-52. PMID 1337146 DOI: 10.1210/mend.6.12.1337146  1
1992 Graf R, Mattera R, Codina J, Estes MK, Birnbaumer L. A truncated recombinant alpha subunit of Gi3 with a reduced affinity for beta gamma dimers and altered guanosine 5'-3-O-(thio)triphosphate binding. The Journal of Biological Chemistry. 267: 24307-14. PMID 1332951  0.52
1992 Smith RG, Hamilton S, Hofmann F, Schneider T, Nastainczyk W, Birnbaumer L, Stefani E, Appel SH. Serum antibodies to L-type calcium channels in patients with amyotrophic lateral sclerosis. The New England Journal of Medicine. 327: 1721-8. PMID 1331790 DOI: 10.1056/NEJM199212103272405  0.4
1992 Gudermann T, Nichols C, Levy FO, Birnbaumer M, Birnbaumer L. Ca2+ mobilization by the LH receptor expressed in Xenopus oocytes independent of 3',5'-cyclic adenosine monophosphate formation: evidence for parallel activation of two signaling pathways. Molecular Endocrinology (Baltimore, Md.). 6: 272-8. PMID 1314958 DOI: 10.1210/mend.6.2.1314958  1
1992 Gudermann T, Birnbaumer M, Birnbaumer L. Evidence for dual coupling of the murine luteinizing hormone receptor to adenylyl cyclase and phosphoinositide breakdown and Ca2+ mobilization. Studies with the cloned murine luteinizing hormone receptor expressed in L cells. The Journal of Biological Chemistry. 267: 4479-88. PMID 1311310  1
1991 Brown AM, Yatani A, Kirsch G, Okabe K, VanDongen AM, Birnbaumer L. Control of K+ channels by G proteins. Journal of Bioenergetics and Biomembranes. 23: 499-507. PMID 1917906  0.36
1991 Codina J, Grenet D, Chang KJ, Birnbaumer L. Urea gradient/SDS-PAGE; a useful tool in the investigation of signal transducing G proteins. Journal of Receptor Research. 11: 587-601. PMID 1909362  0.52
1991 Sanford J, Codina J, Birnbaumer L. Gamma-subunits of G proteins, but not their alpha- or beta-subunits, are polyisoprenylated. Studies on post-translational modifications using in vitro translation with rabbit reticulocyte lysates. The Journal of Biological Chemistry. 266: 9570-9. PMID 1903391  0.52
1991 Spicher K, Klinz FJ, Rudolph U, Codina J, Birnbaumer L, Schultz G, Rosenthal W. Identification of the G-protein alpha-subunit encoded by alpha o2 cDNA as a 39 kDa pertussis toxin substrate. Biochemical and Biophysical Research Communications. 175: 473-9. PMID 1902093  0.52
1991 Davies AO, Su CJ, Balasubramanyam A, Codina J, Birnbaumer L. Abnormal guanine nucleotide regulatory protein in MVP dysautonomia: evidence from reconstitution of Gs. The Journal of Clinical Endocrinology and Metabolism. 72: 867-75. PMID 1900864 DOI: 10.1210/jcem-72-4-867  1
1991 Codina J, Carty DJ, Birnbaumer L, Iyengar R. Purification of G proteins. Methods in Enzymology. 195: 177-88. PMID 1851927  0.52
1991 Birnbaumer L, Perez-Reyes E, Bertrand P, Gudermann T, Wei XY, Kim H, Castellano A, Codina J. Molecular diversity and function of G proteins and calcium channels. Biology of Reproduction. 44: 207-24. PMID 1849023 DOI: 10.1095/biolreprod44.2.207  1
1991 Balasubramanyam A, Davies AO, Codina J, Birnbaumer L. Abnormal Gs function in mitral valve prolapse dysautonomia is not associated with abnormal alpha S cDNA sequence. Life Sciences. 48: 789-93. PMID 1847232  0.52
1991 Brown AM, Yatani A, Kirsch G, VanDongen AM, Schubert B, Codina J, Birnbaumer L. Regulation of ionic channels by G proteins. Advances in Experimental Medicine and Biology. 308: 119-34. PMID 1724872  0.52
1991 Wei XY, Perez-Reyes E, Lacerda AE, Schuster G, Brown AM, Birnbaumer L. Heterologous regulation of the cardiac Ca2+ channel alpha 1 subunit by skeletal muscle beta and gamma subunits. Implications for the structure of cardiac L-type Ca2+ channels. The Journal of Biological Chemistry. 266: 21943-7. PMID 1718988  1
1991 Perez-Reyes E, Wei XY, Gudermann T, Birnbaumer L. The use of PCR to probe calcium channel diversity. Journal of Receptor Research. 11: 553-76. PMID 1715921 DOI: 10.3109/10799899109066427  1
1991 Schmidt A, Hescheler J, Offermanns S, Spicher K, Hinsch KD, Klinz FJ, Codina J, Birnbaumer L, Gausepohl H, Frank R. Involvement of pertussis toxin-sensitive G-proteins in the hormonal inhibition of dihydropyridine-sensitive Ca2+ currents in an insulin-secreting cell line (RINm5F). The Journal of Biological Chemistry. 266: 18025-33. PMID 1680855  0.52
1991 Lacerda AE, Kim HS, Ruth P, Perez-Reyes E, Flockerzi V, Hofmann F, Birnbaumer L, Brown AM. Normalization of current kinetics by interaction between the alpha 1 and beta subunits of the skeletal muscle dihydropyridine-sensitive Ca2+ channel. Nature. 352: 527-30. PMID 1650913 DOI: 10.1038/352527a0  1
1990 Cantiello HF, Patenaude CR, Codina J, Birnbaumer L, Ausiello DA. G alpha i-3 regulates epithelial Na+ channels by activation of phospholipase A2 and lipoxygenase pathways. The Journal of Biological Chemistry. 265: 21624-8. PMID 2174882  1
1990 Perez-Reyes E, Wei XY, Castellano A, Birnbaumer L. Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes. The Journal of Biological Chemistry. 265: 20430-6. PMID 2173707  1
1990 Birnbaumer L, Abramowitz J, Yatani A, Okabe K, Mattera R, Graf R, Sanford J, Codina J, Brown AM. Roles of G proteins in coupling of receptors to ionic channels and other effector systems. Critical Reviews in Biochemistry and Molecular Biology. 25: 225-44. PMID 2171876 DOI: 10.3109/10409239009090610  0.52
1990 Yatani A, Birnbaumer L, Brown AM. Direct coupling of the somatostatin receptor to potassium channels by a G protein. Metabolism: Clinical and Experimental. 39: 91-5. PMID 2169576  0.36
1990 Pelzer S, Shuba YM, Asai T, Codina J, Birnbaumer L, McDonald TF, Pelzer D. Membrane-delimited stimulation of heart cell calcium current by beta-adrenergic signal-transducing Gs protein. The American Journal of Physiology. 259: H264-7. PMID 2165365  1
1990 Kim HS, Wei XY, Ruth P, Perez-Reyes E, Flockerzi V, Hofmann F, Birnbaumer L. Studies on the structural requirements for the activity of the skeletal muscle dihydropyridine receptor/slow Ca2+ channel. Allosteric regulation of dihydropyridine binding in the absence of alpha 2 and beta components of the purified protein complex. The Journal of Biological Chemistry. 265: 11858-63. PMID 2164019  1
1990 Rampe D, Kim HS, Lacerda AE, Birnbaumer L, Brown AM. [3H]PN200-110 binding in a fibroblast cell line transformed with the alpha 1 subunit of the skeletal muscle L-type Ca2+ channel. Biochemical and Biophysical Research Communications. 169: 825-31. PMID 2163635  0.36
1990 Liao CF, Schilling WP, Birnbaumer M, Birnbaumer L. Cellular responses to stimulation of the M5 muscarinic acetylcholine receptor as seen in murine L cells. The Journal of Biological Chemistry. 265: 11273-84. PMID 2162842  1
1990 Birnbaumer L, Abramowitz J, Brown AM. Receptor-effector coupling by G proteins. Biochimica Et Biophysica Acta. 1031: 163-224. PMID 2160274 DOI: 10.1016/0304-4157(90)90007-Y  1
1990 Iyengar R, Birnbaumer L. Roles of G proteins and G protein subunits in signal transduction. Lymphokine Research. 9: 533-7. PMID 2128642  1
1990 Bertrand P, Sanford J, Rudolph U, Codina J, Birnbaumer L. At least three alternatively spliced mRNAs encoding two alpha subunits of the Go GTP-binding protein can be expressed in a single tissue. The Journal of Biological Chemistry. 265: 18576-80. PMID 2120235  0.52
1990 Kirsch GE, Codina J, Birnbaumer L, Brown AM. Coupling of ATP-sensitive K+ channels to A1 receptors by G proteins in rat ventricular myocytes. The American Journal of Physiology. 259: H820-6. PMID 2118729  0.52
1990 Olate J, Martinez S, Purcell P, Jorquera H, Codina J, Birnbaumer L, Allende J. Molecular cloning and sequence determination of four different cDNA species coding for alpha-subunits of G proteins from Xenopus laevis oocytes. Febs Letters. 268: 27-31. PMID 2116977 DOI: 10.1016/0014-5793(90)80964-K  0.36
1990 Okabe K, Yatani A, Evans T, Ho YK, Codina J, Birnbaumer L, Brown AM. Beta gamma dimers of G proteins inhibit atrial muscarinic K+ channels. The Journal of Biological Chemistry. 265: 12854-8. PMID 2115883  0.52
1990 Hsu WH, Rudolph U, Sanford J, Bertrand P, Olate J, Nelson C, Moss LG, Boyd AE, Codina J, Birnbaumer L. Molecular cloning of a novel splice variant of the alpha subunit of the mammalian Go protein. The Journal of Biological Chemistry. 265: 11220-6. PMID 2113531  1
1990 Birnbaumer L. G proteins in signal transduction. Annual Review of Pharmacology and Toxicology. 30: 675-705. PMID 2111655 DOI: 10.1146/annurev.pa.30.040190.003331  1
1990 Yatani A, Okabe K, Birnbaumer L, Brown AM. Detergents, dimeric G beta gamma, and eicosanoid pathways to muscarinic atrial K+ channels. The American Journal of Physiology. 258: H1507-14. PMID 2110781  0.36
1990 Carty DJ, Padrell E, Codina J, Birnbaumer L, Hildebrandt JD, Iyengar R. Distinct guanine nucleotide binding and release properties of the three Gi proteins. The Journal of Biological Chemistry. 265: 6268-73. PMID 2108158  0.52
1990 Brown AM, Yatani A, Codina J, Birnbaumer L. Gating of atrial muscarinic K+ channels by G proteins. Progress in Clinical and Biological Research. 334: 303-12. PMID 2106695  0.52
1990 Birnbaumer L, Brown AM. G proteins and the mechanism of action of hormones, neurotransmitters, and autocrine and paracrine regulatory factors. The American Review of Respiratory Disease. 141: S106-14. PMID 1968735 DOI: 10.1164/ajrccm/141.3_Pt_2.S106  0.36
1990 Birnbaumer L, Yatani A, VanDongen AM, Graf R, Codina J, Okabe K, Mattera R, Brown AM. G protein coupling of receptors to ionic channels and other effector systems. British Journal of Clinical Pharmacology. 30: 13S-22S. PMID 1702677  0.52
1990 Yatani A, Okabe K, Codina J, Birnbaumer L, Brown AM. Heart rate regulation by G proteins acting on the cardiac pacemaker channel. Science (New York, N.Y.). 249: 1163-6. PMID 1697697  0.52
1990 Birnbaumer L, Yatani A, VanDongen AM, Graf R, Codina J, Okabe K, Mattera R, Brown AM. G protein coupling of receptors to ionic channels and other effector systems. Society of General Physiologists Series. 45: 169-83. PMID 1696032  1
1990 Brown AM, Yatani A, VanDongen AM, Kirsch GE, Codina J, Birnbaumer L. Networking ionic channels by G proteins. Society of General Physiologists Series. 45: 1-9. PMID 1696031  1
1990 Brown AM, Birnbaumer L. Ionic channels and their regulation by G protein subunits. Annual Review of Physiology. 52: 197-213. PMID 1691904 DOI: 10.1146/annurev.ph.52.030190.001213  0.36
1989 Liao CF, Themmen AP, Joho R, Barberis C, Birnbaumer M, Birnbaumer L. Molecular cloning and expression of a fifth muscarinic acetylcholine receptor. The Journal of Biological Chemistry. 264: 7328-37. PMID 2540186  0.68
1989 Mattera R, Graziano MP, Yatani A, Zhou Z, Graf R, Codina J, Birnbaumer L, Gilman AG, Brown AM. Splice variants of the alpha subunit of the G protein Gs activate both adenylyl cyclase and calcium channels. Science (New York, N.Y.). 243: 804-7. PMID 2536957  1
1989 Mattera R, Yatani A, Kirsch GE, Graf R, Okabe K, Olate J, Codina J, Brown AM, Birnbaumer L. Recombinant alpha i-3 subunit of G protein activates Gk-gated K+ channels. The Journal of Biological Chemistry. 264: 465-71. PMID 2535845  0.52
1989 Sunyer T, Monastirsky B, Codina J, Birnbaumer L. Studies on nucleotide and receptor regulation of Gi proteins: effects of pertussis toxin. Molecular Endocrinology (Baltimore, Md.). 3: 1115-24. PMID 2507904 DOI: 10.1210/mend-3-7-1115  0.52
1989 Olate J, Jorquera H, Purcell P, Codina J, Birnbaumer L, Allende JE. Molecular cloning and sequence determination of a cDNA coding for the alpha-subunit of a Go-type protein of Xenopus laevis oocytes. Febs Letters. 244: 188-92. PMID 2494063 DOI: 10.1016/0014-5793(89)81190-1  1
1989 Birnbaumer L, Codina J, Yatani A, Mattera R, Graf R, Olate J, Themmen AP, Liao CF, Sanford J, Okabe K. Molecular basis of regulation of ionic channels by G proteins. Recent Progress in Hormone Research. 45: 121-206; discussion . PMID 2479060  1
1989 Birnbaumer L, VanDongen AM, Codina J, Yatani A, Mattera R, Graf R, Brown AM. Identification of G protein-gated and G protein-modulated ionic channels. Molecular basis for G protein action. Society of General Physiologists Series. 44: 17-54. PMID 2476853  1
1989 Perez-Reyes E, Kim HS, Lacerda AE, Horne W, Wei XY, Rampe D, Campbell KP, Brown AM, Birnbaumer L. Induction of calcium currents by the expression of the alpha 1-subunit of the dihydropyridine receptor from skeletal muscle. Nature. 340: 233-6. PMID 2474131 DOI: 10.1038/340233a0  1
1989 Brown AM, Birnbaumer L. Ion channels and G proteins. Hospital Practice (Office Ed.). 24: 189-93, 198, 202-4. PMID 2473087  0.36
1989 Brown AM, Yatani A, Imoto Y, Codina J, Mattera R, Birnbaumer L. Direct G-protein regulation of Ca2+ channels. Annals of the New York Academy of Sciences. 560: 373-86. PMID 2472766  0.52
1989 Brown AM, Yatani A, Codina J, Birnbaumer L. G protein-gated channels. A third major category of ionic channels. American Journal of Hypertension. 2: 124-7. PMID 2465009  0.52
1988 Brown AM, Yatani A, Imoto Y, Kirsch G, Hamm H, Codina J, Mattera R, Birnbaumer L. Direct coupling of G proteins to ionic channels. Cold Spring Harbor Symposia On Quantitative Biology. 53: 365-73. PMID 3151174  0.52
1988 VanDongen AM, Codina J, Olate J, Mattera R, Joho R, Birnbaumer L, Brown AM. Newly identified brain potassium channels gated by the guanine nucleotide binding protein Go. Science (New York, N.Y.). 242: 1433-7. PMID 3144040  0.52
1988 Yatani A, Mattera R, Codina J, Graf R, Okabe K, Padrell E, Iyengar R, Brown AM, Birnbaumer L. The G protein-gated atrial K+ channel is stimulated by three distinct Gi alpha-subunits. Nature. 336: 680-2. PMID 3143915 DOI: 10.1038/336680a0  0.52
1988 Imoto Y, Yatani A, Reeves JP, Codina J, Birnbaumer L, Brown AM. Alpha-subunit of Gs directly activates cardiac calcium channels in lipid bilayers. The American Journal of Physiology. 255: H722-8. PMID 2845814 DOI: 10.1152/ajpheart.1988.255.4.H722  0.52
1988 Olate J, Mattera R, Codina J, Birnbaumer L. Reticulocyte lysates synthesize an active alpha subunit of the stimulatory G protein Gs. The Journal of Biological Chemistry. 263: 10394-400. PMID 2839488  0.52
1988 Abramowitz J, Mattera R, Liao CF, Olate J, Perez-Ripoll E, Birnbaumer L, Codina J. Screening of cDNA libraries with oligonucleotides as applied to signal transducing G proteins, receptors and effectors. Journal of Receptor Research. 8: 561-88. PMID 2838629  0.52
1988 Birnbaumer L, Codina J, Mattera R, Yatani A, Graf R, Olate J, Sanford J, Brown AM. Receptor-effector coupling by G proteins: purification of human erythrocyte Gi-2 and Gi-3 and analysis of effector regulation using recombinant alpha subunits synthesized in Escherichia coli. Cold Spring Harbor Symposia On Quantitative Biology. 53: 229-39. PMID 2474404  0.52
1988 Yatani A, Hamm H, Codina J, Mazzoni MR, Birnbaumer L, Brown AM. A monoclonal antibody to the alpha subunit of Gk blocks muscarinic activation of atrial K+ channels. Science (New York, N.Y.). 241: 828-31. PMID 2457252  0.52
1988 Yatani A, Imoto Y, Codina J, Hamilton SL, Brown AM, Birnbaumer L. The stimulatory G protein of adenylyl cyclase, G(s), also stimulates dihydropyridine-sensitive Ca2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist Journal of Biological Chemistry. 263: 9887-9895. PMID 2454923  1
1988 Kirsch GE, Yatani A, Codina J, Birnbaumer L, Brown AM. Alpha-subunit of Gk activates atrial K+ channels of chick, rat, and guinea pig. The American Journal of Physiology. 254: H1200-5. PMID 2454586 DOI: 10.1152/ajpheart.1988.254.6.H1200  0.52
1988 Codina J, Olate J, Abramowitz J, Mattera R, Cook RG, Birnbaumer L. Alpha i-3 cDNA encodes the alpha subunit of Gk, the stimulatory G protein of receptor-regulated K+ channels. The Journal of Biological Chemistry. 263: 6746-50. PMID 2452165  0.52
1988 Brown AM, Birnbaumer L. Direct G protein gating of ion channels. The American Journal of Physiology. 254: H401-10. PMID 2450476 DOI: 10.1152/ajpheart.1988.254.3.H401  0.36
1987 Ribeiro-Neto F, Birnbaumer L, Field JB. Incubation of bovine thyroid slices with thyrotropin is associated with a decrease in the ability of pertussus toxin to adenosine diphosphate-ribosylate guanine nucleotide regulatory component(s) Molecular Endocrinology. 1: 482-490. PMID 3155264  1
1987 Birnbaumer L, Codina J, Mattera R, Yatani A, Scherer N, Toro MJ, Brown AM. Signal transduction by G proteins. Kidney International. Supplement. 23: S14-42. PMID 2450220  0.52
1987 Yatani A, Codina J, Imoto Y, Reeves JP, Birnbaumer L, Brown AM. A G protein directly regulates mammalian cardiac calcium channels. Science (New York, N.Y.). 238: 1288-92. PMID 2446390  0.52
1972 Birnbaumer L, Pohl SL, Rodbell M, Sundby F. The glucagon-sensitive adenylate cyclase system in plasma membranes of rat liver. VII. Hormonal stimulation: reversibility and dependence on concentration of free hormone. The Journal of Biological Chemistry. 247: 2038-43. PMID 5016642  1
1972 Pohl SL, Krans HM, Birnbaumer L, Rodbell M. Inactivation of glucagon by plasma membranes of rat liver. The Journal of Biological Chemistry. 247: 2295-301. PMID 4337268  1
1971 Rodbell M, Birnbaumer L, Pohl SL, Sundby F. The reaction of glucagon with its receptor: evidence for discrete regions of activity and binding in the glucagon molecule. Proceedings of the National Academy of Sciences of the United States of America. 68: 909-13. PMID 5280527  1
1971 Rodbell M, Birnbaumer L, Pohl SL. Characteristics of glucagon action on the hepatic adenylate cyclase system. The Biochemical Journal. 125: 58P-59P. PMID 5145874  1
1971 Rodbell M, Krans HM, Pohl SL, Birnbaumer L. The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. IV. Effects of guanylnucleotides on binding of 125I-glucagon. The Journal of Biological Chemistry. 246: 1872-6. PMID 4993962  1
1971 Pohl SL, Birnbaumer L, Rodbell M. The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. I. Properties. The Journal of Biological Chemistry. 246: 1849-56. PMID 4993961  1
1971 Rodbell M, Birnbaumer L, Pohl SL, Krans HM. The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. V. An obligatory role of guanylnucleotides in glucagon action. The Journal of Biological Chemistry. 246: 1877-82. PMID 4926550  1
1971 Pohl SL, Krans HM, Kozyreff V, Birnbaumer L, Rodbell M. The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. VI. Evidence for a role of membrane lipids. The Journal of Biological Chemistry. 246: 4447-54. PMID 4328442  1
1971 Rodbell M, Krans HM, Pohl SL, Birnbaumer L. The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. 3. Binding of glucagon: method of assay and specificity. The Journal of Biological Chemistry. 246: 1861-71. PMID 4323237  1
1971 Birnbaumer L, Pohl SL, Rodbell M. The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. II. Comparison between glucagon- and fluoride-stimulated activities. The Journal of Biological Chemistry. 246: 1857-60. PMID 4323236  1
1970 Rodbell M, Birnbaumer L, Pohl SL, Krans HM. [Properties of the adenyl cyclase systems in liver and adipose cells: the mode of action of hormones]. Acta Diabetologica Latina. 7: 9-63. PMID 5474742  1
1970 Birnbaumer L, Pohl SL, Michiel H, Krans MJ, Rodbell M. The actions of hormones on the adenyl cyclase system. Advances in Biochemical Psychopharmacology. 3: 185-208. PMID 4399634  1
1970 Rodbell M, Birnbaumer L, Pohl SL. Adenyl cyclase in fat cells. 3. Stimulation by secretin and the effects of trypsin on the receptors for lipolytic hormones. The Journal of Biological Chemistry. 245: 718-22. PMID 4313606  1
1969 Birnbaumer L, Rodbell M. Adenyl cyclase in fat cells. II. Hormone receptors. The Journal of Biological Chemistry. 244: 3477-82. PMID 4307453  1
1969 Birnbaumer L, Pohl SL, Rodbell M. Adenyl cyclase in fat cells. 1. Properties and the effects of adrenocorticotropin and fluoride. The Journal of Biological Chemistry. 244: 3468-76. PMID 4307452  1
1969 Pohl SL, Birnbaumer L, Rodbell M. Glucagon-sensitive adenyl cylase in plasma membrane of hepatic parenchymal cells. Science (New York, N.Y.). 164: 566-7. PMID 4305077  1
1968 Rodbell M, Jones AB, Chiappe de Cingolani GE, Birnbaumer L. The actions of insulin and catabolic hormones on the plasma membrane of the fat cells. Recent Progress in Hormone Research. 24: 215-54. PMID 4302429  1
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