Simon Kaja - Publications

Affiliations: 
Molecular Pharmacology and Neuroscience Loyola University Chicago, Chicago, IL, United States 

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ghosh AK, Rao VR, Wisniewski VJ, Zigrossi AD, Floss J, Koulen P, Stubbs EB, Kaja S. Differential Activation of Glioprotective Intracellular Signaling Pathways in Primary Optic Nerve Head Astrocytes after Treatment with Different Classes of Antioxidants. Antioxidants (Basel, Switzerland). 9. PMID 32316287 DOI: 10.3390/antiox9040324  0.556
2019 Žiniauskaitė A, Ragauskas S, Ghosh AK, Thapa R, Roessler AE, Koulen P, Kalesnykas G, Hakkarainen JJ, Kaja S. Manganese(III) tetrakis(1-methyl-4-pyridyl) porphyrin, a superoxide dismutase mimetic, reduces disease severity in in vitro and in vivo models for dry-eye disease. The Ocular Surface. PMID 30807830 DOI: 10.1016/J.Jtos.2019.02.006  0.571
2017 Sandoval A, Duran P, Gandini MA, Andrade A, Almanza A, Kaja S, Felix R. Regulation of L-type CaV1.3 channel activity and insulin secretion by the cGMP-PKG signaling pathway. Cell Calcium. 66: 1-9. PMID 28807144 DOI: 10.1016/J.Ceca.2017.05.008  0.318
2017 Kaja S, Payne AJ, Naumchuk Y, Koulen P. Quantification of Lactate Dehydrogenase for Cell Viability Testing Using Cell Lines and Primary Cultured Astrocytes. Current Protocols in Toxicology. 72: 2.26.1-2.26.10. PMID 28463416 DOI: 10.1002/Cptx.21  0.734
2017 Maciulaitiene R, Pakuliene G, Kaja S, Pauza DH, Kalesnykas G, Januleviciene I. Glioprotection of Retinal Astrocytes After Intravitreal Administration of Memantine in the Mouse Optic Nerve Crush Model. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 23: 1173-1179. PMID 28265105 DOI: 10.12659/Msm.899699  0.308
2017 Naumchuk YA, Maksymenko VB, Kaja S. Optimization of Cell Viability Assays for Screening Glioprotective Compounds in Primary Rat Optic Nerve Head Astrocytes Research Bulletin of the National Technical University of Ukraine "Kyiv Politechnic Institute. 20-26. DOI: 10.20535/1810-0546.2017.6.119387  0.337
2016 Means JC, Gerdes BC, Kaja S, Sumien N, Payne AJ, Stark DA, Borden PK, Price JL, Koulen P. Caspase-3-Dependent Proteolytic Cleavage of Tau Causes Neurofibrillary Tangles and Results in Cognitive Impairment During Normal Aging. Neurochemical Research. PMID 27220334 DOI: 10.1007/S11064-016-1942-9  0.705
2016 Richter F, Koulen P, Kaja S. N-Palmitoylethanolamine Prevents the Run-down of Amplitudes in Cortical Spreading Depression Possibly Implicating Proinflammatory Cytokine Release. Scientific Reports. 6: 23481. PMID 27004851 DOI: 10.1038/Srep23481  0.575
2015 Kaja S, Payne AJ, Nielsen EØ, Thompson CL, van den Maagdenberg AM, Koulen P, Snutch TP. Differential cerebellar GABAA receptor expression in mice with mutations in CaV2.1 (P/Q-type) calcium channels. Neuroscience. PMID 26208839 DOI: 10.1016/J.Neuroscience.2015.07.044  0.581
2015 Kaja S, Payne AJ, Naumchuk Y, Levy D, Zaidi DH, Altman AM, Nawazish S, Ghuman JK, Gerdes BC, Moore MA, Koulen P. Plate reader-based cell viability assays for glioprotection using primary rat optic nerve head astrocytes. Experimental Eye Research. PMID 26048476 DOI: 10.1016/J.Exer.2015.05.023  0.751
2015 Rao VR, Perez-Neut M, Kaja S, Gentile S. Voltage-gated ion channels in cancer cell proliferation. Cancers. 7: 849-75. PMID 26010603 DOI: 10.3390/Cancers7020813  0.301
2015 Kaja S, Shah AA, Haji SA, Patel KB, Naumchuk Y, Zabaneh A, Gerdes BC, Kunjukunju N, Sabates NR, Cassell MA, Lord RK, Pikey KP, Poulose A, Koulen P. Nampt/PBEF/visfatin serum levels: a new biomarker for retinal blood vessel occlusions. Clinical Ophthalmology (Auckland, N.Z.). 9: 611-8. PMID 25897200 DOI: 10.2147/Opth.S80784  0.751
2015 Kaja S, Payne AJ, Singh T, Ghuman JK, Sieck EG, Koulen P. An optimized lactate dehydrogenase release assay for screening of drug candidates in neuroscience. Journal of Pharmacological and Toxicological Methods. 73: 1-6. PMID 25681780 DOI: 10.1016/J.Vascn.2015.02.001  0.725
2015 Payne AJ, Kaja S, Koulen P. Regulation of ryanodine receptor-mediated calcium signaling by presenilins. Receptors & Clinical Investigation. 2: e449. PMID 25646163 DOI: 10.14800/Rci.449  0.766
2015 Kaja S, Payne AJ, Patel KR, Naumchuk Y, Koulen P. Differential subcellular Ca2+ signaling in a highly specialized subpopulation of astrocytes. Experimental Neurology. 265: 59-68. PMID 25542978 DOI: 10.1016/J.Expneurol.2014.12.014  0.751
2015 Kaja S, Sumien N, Shah VV, Puthawala I, Maynard AN, Khullar N, Payne AJ, Forster MJ, Koulen P. Loss of Spatial Memory, Learning, and Motor Function During Normal Aging Is Accompanied by Changes in Brain Presenilin 1 and 2 Expression Levels. Molecular Neurobiology. 52: 545-54. PMID 25204494 DOI: 10.1007/S12035-014-8877-4  0.74
2014 Nielsen EO, Kaja S. GABAA Receptor Expression in the Forebrain of Ataxic Rolling Nagoya Mice. Biology and Medicine (Aligarh). 6. PMID 25309056 DOI: 10.4172/1234-3425.1000198  0.322
2014 McCalley AE, Kaja S, Payne AJ, Koulen P. Resveratrol and calcium signaling: molecular mechanisms and clinical relevance. Molecules (Basel, Switzerland). 19: 7327-40. PMID 24905603 DOI: 10.3390/Molecules19067327  0.751
2014 Payne AJ, Kaja S, Naumchuk Y, Kunjukunju N, Koulen P. Antioxidant drug therapy approaches for neuroprotection in chronic diseases of the retina. International Journal of Molecular Sciences. 15: 1865-86. PMID 24473138 DOI: 10.3390/Ijms15021865  0.747
2014 Kaja S, Naumchuk Y, Grillo SL, Borden PK, Koulen P. Differential up-regulation of Vesl-1/Homer 1 protein isoforms associated with decline in visual performance in a preclinical glaucoma model. Vision Research. 94: 16-23. PMID 24219919 DOI: 10.1016/J.Visres.2013.10.018  0.781
2014 Kaja S. Presenilins: A novel class of calcium modulators Journal of Neurology and Neurophysiology. DOI: 10.4172/2155-9562.S1.016  0.39
2014 Kaja S, Payne AJ. Novel Treatment Strategies for Neurological and Neurodegenerative Diseases Biology and Medicine. 1. DOI: 10.4172/0974-8369.S1-E101  0.351
2013 Payne AJ, Gerdes BC, Kaja S, Koulen P. Insert sequence length determines transfection efficiency and gene expression levels in bicistronic mammalian expression vectors. International Journal of Biochemistry and Molecular Biology. 4: 201-8. PMID 24380024  0.727
2013 Payne AJ, Kaja S, Sabates NR, Koulen P. A case for neuroprotection in ophthalmology: developments in translational research. Missouri Medicine. 110: 429-36. PMID 24279196  0.728
2013 Payne AJ, Gerdes BC, Naumchuk Y, McCalley AE, Kaja S, Koulen P. Presenilins regulate the cellular activity of ryanodine receptors differentially through isotype-specific N-terminal cysteines. Experimental Neurology. 250: 143-50. PMID 24029002 DOI: 10.1016/J.Expneurol.2013.09.001  0.76
2013 Kaja S, Sumien N, Borden PK, Khullar N, Iqbal M, Collins JL, Forster MJ, Koulen P. Homer-1a immediate early gene expression correlates with better cognitive performance in aging. Age (Dordrecht, Netherlands). 35: 1799-808. PMID 23054826 DOI: 10.1007/S11357-012-9479-6  0.588
2012 Kaja S, Hilgenberg JD, Collins JL, Shah AA, Wawro D, Zimmerman S, Magnusson R, Koulen P. Detection of novel biomarkers for ovarian cancer with an optical nanotechnology detection system enabling label-free diagnostics. Journal of Biomedical Optics. 17: 081412-1. PMID 23224173 DOI: 10.1117/1.Jbo.17.8.081412  0.559
2012 Romero-Suarez S, Mo C, Touchberry C, Lara N, Baker K, Craig R, Brotto L, Andresen J, Wacker M, Kaja S, Abreu E, Dillmann W, Mestril R, Brotto M, Nosek T. Hyperthermia: From diagnostic and treatments to new discoveries Recent Patents On Biotechnology. 6: 172-183. PMID 23092438 DOI: 10.2174/1872208311206030172  0.592
2012 Kaja S, Goad DL, Ali F, Abraham A, Rebenitsch RL, Teymoorian S, Krishna R, Koulen P. Evaluation of tensile strength of tissue adhesives and sutures for clear corneal incisions using porcine and bovine eyes, with a novel standardized testing platform. Clinical Ophthalmology (Auckland, N.Z.). 6: 305-9. PMID 22399842 DOI: 10.2147/Opth.S29859  0.731
2012 Kaja S, Mafe OA, Parikh RA, Kandula P, Reddy CA, Gregg EV, Xin H, Mitchell P, Grillo MA, Koulen P. Distribution and function of polycystin-2 in mouse retinal ganglion cells Neuroscience. 202: 99-107. PMID 22155264 DOI: 10.1016/J.Neuroscience.2011.11.047  0.603
2012 Burroughs SL, Duncan RS, Rayudu P, Kandula P, Payne AJ, Clark JL, Koulen P, Kaja S. Plate reader-based assays for measuring cell viability, neuroprotection and calcium in primary neuronal cultures. Journal of Neuroscience Methods. 203: 141-5. PMID 21968036 DOI: 10.1016/J.Jneumeth.2011.09.007  0.765
2011 Kaja S, Hilgenberg JD, Everett E, Olitsky SE, Gossage J, Koulen P. Effects of dilution and prolonged storage with preservative in a polyethylene container on Bevacizumab (Avastin™) for topical delivery as a nasal spray in anti-hereditary hemorrhagic telangiectasia and related therapies. Human Antibodies. 20: 95-101. PMID 22129679 DOI: 10.3233/Hab-2011-0244  0.578
2011 Kaja S, Hilgenberg JD, Rybalchenko V, Medina-Ortiz WE, Gregg EV, Koulen P. Polycystin-2 expression and function in adult mouse lacrimal acinar cells. Investigative Ophthalmology & Visual Science. 52: 5605-11. PMID 21508103 DOI: 10.1167/Iovs.10-7114  0.609
2011 Burroughs SL, Kaja S, Koulen P. Quantification of deficits in spatial visual function of mouse models for glaucoma. Investigative Ophthalmology & Visual Science. 52: 3654-9. PMID 21330670 DOI: 10.1167/Iovs.10-7106  0.571
2011 Garg P, Duncan RS, Kaja S, Zabaneh A, Chapman KD, Koulen P. Lauroylethanolamide and linoleoylethanolamide improve functional outcome in a rodent model for stroke. Neuroscience Letters. 492: 134-8. PMID 21296126 DOI: 10.1016/J.Neulet.2011.01.073  0.736
2011 Kaja S, Duncan RS, Longoria S, Hilgenberg JD, Payne AJ, Desai NM, Parikh RA, Burroughs SL, Gregg EV, Goad DL, Koulen P. Novel mechanism of increased Ca2+ release following oxidative stress in neuronal cells involves type 2 inositol-1,4,5-trisphosphate receptors. Neuroscience. 175: 281-91. PMID 21075175 DOI: 10.1016/J.Neuroscience.2010.11.010  0.752
2010 Kaja S, Van de Ven RC, Broos LA, Frants RR, Ferrari MD, Van den Maagdenberg AM, Plomp JJ. Severe and progressive neurotransmitter release aberrations in familial hemiplegic migraine type 1 Cacna1a S218L knock-in mice. Journal of Neurophysiology. 104: 1445-55. PMID 20631222 DOI: 10.1152/Jn.00012.2010  0.329
2010 Duncan RS, Goad DL, Grillo MA, Kaja S, Payne AJ, Koulen P. Control of intracellular calcium signaling as a neuroprotective strategy. Molecules (Basel, Switzerland). 15: 1168-95. PMID 20335972 DOI: 10.3390/Molecules15031168  0.723
2010 van den Maagdenberg AM, Pizzorusso T, Kaja S, Terpolilli N, Shapovalova M, Hoebeek FE, Barrett CF, Gherardini L, van de Ven RC, Todorov B, Broos LA, Tottene A, Gao Z, Fodor M, De Zeeuw CI, et al. High cortical spreading depression susceptibility and migraine-associated symptoms in Ca(v)2.1 S218L mice. Annals of Neurology. 67: 85-98. PMID 20186955 DOI: 10.1002/Ana.21815  0.305
2010 Garg P, Duncan RS, Kaja S, Koulen P. Intracellular mechanisms of N-acylethanolamine-mediated neuroprotection in a rat model of stroke. Neuroscience. 166: 252-62. PMID 19963043 DOI: 10.1016/J.Neuroscience.2009.11.069  0.743
2009 Plomp JJ, Maagdenberg AMJMvd, Kaja S. The ataxic Cacna1a-mutant mouse rolling nagoya: an overview of neuromorphological and electrophysiological findings. The Cerebellum. 8: 222-230. PMID 19484318 DOI: 10.1007/S12311-009-0117-5  0.332
2007 Kaja S, Hann V, Payne HL, Thompson CL. Aberrant cerebellar granule cell-specific GABAA receptor expression in the epileptic and ataxic mouse mutant, Tottering Neuroscience. 148: 115-125. PMID 17614209 DOI: 10.1016/J.Neuroscience.2007.03.055  0.311
2007 Kaja S, van de Ven RC, van Dijk JG, Verschuuren JJ, Arahata K, Frants RR, Ferrari MD, van den Maagdenberg AM, Plomp JJ. Severely impaired neuromuscular synaptic transmission causes muscle weakness in the Cacna1a-mutant mouse rolling Nagoya. The European Journal of Neuroscience. 25: 2009-20. PMID 17439489 DOI: 10.1111/J.1460-9568.2007.05438.X  0.312
2007 Kaja S, Ven RCGvd, Broos LAM, Frants RR, Ferrari MD, Maagdenberg AMJMvd, Plomp JJ. Characterization of acetylcholine release and the compensatory contribution of non-Cav2.1 channels at motor nerve terminals of leaner Cav2.1-mutant mice Neuroscience. 144: 1278-1287. PMID 17161543 DOI: 10.1016/J.Neuroscience.2006.11.006  0.304
2006 Todorov B, van de Ven RC, Kaja S, Broos LA, Verbeek SJ, Plomp JJ, Ferrari MD, Frants RR, van den Maagdenberg AM. Conditional inactivation of the Cacna1a gene in transgenic mice. Genesis (New York, N.Y. : 2000). 44: 589-94. PMID 17146767 DOI: 10.1002/Dvg.20255  0.312
2005 Kaja S, van de Ven RC, Broos LA, Veldman H, van Dijk JG, Verschuuren JJ, Frants RR, Ferrari MD, van den Maagdenberg AM, Plomp JJ. Gene dosage-dependent transmitter release changes at neuromuscular synapses of CACNA1A R192Q knockin mice are non-progressive and do not lead to morphological changes or muscle weakness. Neuroscience. 135: 81-95. PMID 16111830 DOI: 10.1016/J.Neuroscience.2005.04.069  0.324
2004 van den Maagdenberg AM, Pietrobon D, Pizzorusso T, Kaja S, Broos LA, Cesetti T, van de Ven RC, Tottene A, van der Kaa J, Plomp JJ, Frants RR, Ferrari MD. A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression. Neuron. 41: 701-10. PMID 15003170 DOI: 10.1016/S0896-6273(04)00085-6  0.311
2003 Kaja S, Yang SH, Wei J, Fujitani K, Liu R, Brun-Zinkernagel AM, Simpkins JW, Inokuchi K, Koulen P. Estrogen protects the inner retina from apoptosis and ischemia-induced loss of Vesl-1L/Homer 1c immunoreactive synaptic connections. Investigative Ophthalmology & Visual Science. 44: 3155-62. PMID 12824266 DOI: 10.1167/Iovs.02-1204  0.707
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