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Robert G. Spiro - Publications

Affiliations: 
Biological Chemistry Harvard Medical School, Boston, MA, United States 
Area:
glycoproteins
Website:
http://home.comcast.net/~robertgspiro/

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2004 Spiro RG. Role of N-linked polymannose oligosaccharides in targeting glycoproteins for endoplasmic reticulum-associated degradation Cellular and Molecular Life Sciences. 61: 1025-1041. PMID 15112051 DOI: 10.1007/s00018-004-4037-8  0.305
2002 Spiro RG. Protein glycosylation: Nature, distribution, enzymatic formation, and disease implications of glycopeptide bonds Glycobiology. 12: 43R-56R. PMID 12042244 DOI: 10.1093/Glycob/12.4.43R  0.366
2001 Spiro MJ, Spiro RG. Release of polymannose oligosaccharides from vesicular stomatitis virus G protein during endoplasmic reticulum-associated degradation Glycobiology. 11: 803-811. PMID 11588156 DOI: 10.1093/Glycob/11.10.803  0.341
2000 Dong Z, Zuber C, Spiro MJ, Spiro RG, Roth J. Immunohistochemical evaluation of endomannosidase distribution in rat tissues: Evidence for cell type-specific expression Histochemistry and Cell Biology. 114: 461-467. PMID 11201607 DOI: 10.1007/S004180000216  0.316
2000 Zuber C, Spiro MJ, Guhl B, Spiro RG, Roth J. Golgi apparatus immunolocalization of endomannosidase suggests post-endoplasmic reticulum glucose trimming: Implications for quality control Molecular Biology of the Cell. 11: 4227-4240. PMID 11102520 DOI: 10.1091/Mbc.11.12.4227  0.35
2000 Spiro MJ, Spiro RG. Sulfation of the N-linked oligosaccharides of influenza virus hemagglutinin: Temporal relationships and localization of sulfotransferases Glycobiology. 10: 1235-1242. PMID 11087716 DOI: 10.1093/Glycob/10.11.1235  0.398
2000 Spiro RG. Glucose residues as key determinants in the biosynthesis and quality control of glycoproteins with N-linked oligosaccharides Journal of Biological Chemistry. 275: 35657-35660. PMID 11007802 DOI: 10.1074/Jbc.R000022200  0.317
2000 Edge AS, Spiro RG. A specific structural alteration in the heparan sulphate of human glomerular basement membrane in diabetes. Diabetologia. 43: 1056-9. PMID 10990084 DOI: 10.1007/S001250051489  0.574
2000 Karaivanova VK, Spiro RG. Effect of proteasome inhibitors on the release into the cytosol of free polymannose oligosaccharides from glycoproteins Glycobiology. 10: 727-735. PMID 10910976 DOI: 10.1093/Glycob/10.7.727  0.388
2000 Spiro MJ, Spiro RG. Use of recombinant endomannosidase for evaluation of the processing of N-linked oligosaccharides of glycoproteins and their oligosaccharide-lipid precursors Glycobiology. 10: 521-529. PMID 10764841 DOI: 10.1093/Glycob/10.5.521  0.437
1998 Chandra NC, Spiro MJ, Spiro RG. Identification of a glycoprotein from rat liver mitochondrial inner membrane and demonstration of its origin in the endoplasmic reticulum. The Journal of Biological Chemistry. 273: 19715-21. PMID 9677401 DOI: 10.1074/Jbc.273.31.19715  0.388
1998 Karaivanova VK, Luan P, Spiro RG. Processing of viral envelope glycoprotein by the endomannosidase pathway: Evaluation of host cell specificity Glycobiology. 8: 725-730. PMID 9621113 DOI: 10.1093/Glycob/8.7.725  0.359
1998 Spiro RG, Bhoyroo VD. Characterization of a spleen sulphotransferase responsible for the 6-O-sulphation of the galactose residue in sialyl-N-acetyl-lactosamine sequences Biochemical Journal. 331: 265-271. PMID 9512489 DOI: 10.1042/Bj3310265  0.403
1997 Spiro MJ, Bhoyroo VD, Spiro RG. Molecular cloning and expression of rat liver endo-α-mannosidase, an N- linked oligosaccharide processing enzyme Journal of Biological Chemistry. 272: 29356-29363. PMID 9361017 DOI: 10.1074/Jbc.272.46.29356  0.391
1997 Edge AS, Spiro RG. Structure of the O-linked oligosaccharides from a major thyroid cell surface glycoprotein. Archives of Biochemistry and Biophysics. 343: 73-80. PMID 9210648 DOI: 10.1006/Abbi.1997.0143  0.601
1997 Dairaku K, Spiro RG. Phylogenetic survey of endomannosidase indicates late evolutionary appearance of this N-linked oligosaccharide processing enzyme Glycobiology. 7: 579-586. PMID 9184840 DOI: 10.1093/Glycob/7.4.579  0.385
1997 Weng S, Spiro RG. Demonstration of a peptide: N-glycosidase in the endoplasmic reticulum of rat liver Biochemical Journal. 322: 655-661. PMID 9065790 DOI: 10.1042/Bj3220655  0.397
1996 Weng S, Spiro RG. Evaluation of the early processing routes of N-linked oligosaccharides of glycoproteins through the characterization of Man8GlcNAc2 isomers: Evidence that endomannosidase functions in vivo in the absence of a glucosidase blockade Glycobiology. 6: 861-868. PMID 9023549 DOI: 10.1093/Glycob/6.8.861  0.412
1996 Spiro RG, Yasumoto Y, Bhoyroo V. Characterization of a rat liver Golgi sulphotransferase responsible for the 6-O-sulphation of N-acetylglucosamine residues in β-linkage to mannose: Role in assembly of sialyl-galactosyl-N-acetylglucosamine 6-sulphate sequence of N-linked oligosaccharides Biochemical Journal. 319: 209-216. PMID 8870671 DOI: 10.1042/Bj3190209  0.447
1996 Spiro RG, Zhu Q, Bhoyroo V, Söling HD. Definition of the lectin-like properties of the molecular chaperone, calreticulin, and demonstration of its copurification with endomannosidase from rat liver Golgi. The Journal of Biological Chemistry. 271: 11588-94. PMID 8626722 DOI: 10.1074/Jbc.271.19.11588  0.394
1996 Weng S, Spiro RG. Endoplasmic reticulum kifunensine-resistant α-mannosidase is enzymatically and immunologically related to the cytosolic α-mannosidase Archives of Biochemistry and Biophysics. 325: 113-123. PMID 8554335 DOI: 10.1006/Abbi.1996.0014  0.356
1994 Wakisaka M, Spiro MJ, Spiro RG. Synthesis of type VI collagen by cultured glomerular cells and comparison of its regulation by glucose and other factors with that of type IV collagen Diabetes. 43: 95-103. PMID 8262324 DOI: 10.2337/Diab.43.1.95  0.306
1994 Moore SEH, Spiro RG. Intracellular compartmentalization and degradation of free polymannose oligosaccharides released during glycoprotein biosynthesis Journal of Biological Chemistry. 269: 12715-12721. PMID 8175683  0.34
1994 Hiraizumi S, Spohr U, Spiro RG. Ligand affinity chromatographic purification of rat liver Golgi- endomannosidase Journal of Biological Chemistry. 269: 4697-4700. PMID 8106437  0.304
1993 Danne T, Spiro MJ, Spiro RG. Effect of high glucose on type IV collagen production by cultured glomerular epithelial, endothelial, and mesangial cells Diabetes. 42: 170-177. PMID 8420814 DOI: 10.2337/Diab.42.1.170  0.332
1992 Woodrow D, Moss J, Shore I, Spiro RG. Diabetic glomerulosclerosis - Immunogold ultrastructural studies on the glomerular distribution of type IV collagen and heparan sulphate proteoglycan Journal of Pathology. 167: 49-58. PMID 1625058 DOI: 10.1002/Path.1711670109  0.307
1992 Rabouille C, Spiro RG. Nonselective utilization of the endomannosidase pathway for processing glycoproteins by human hepatoma (HepG2) cells Journal of Biological Chemistry. 267: 11573-11578. PMID 1317871  0.301
1991 Mohan PS, Spiro RG. Characterization of heparan sulfate proteoglycan from calf lens capsule and proteoglycans synthesized by cultured lens epithelial cells: Comparison with other basement membrane proteoglycans Journal of Biological Chemistry. 266: 8567-8575. PMID 2022669  0.313
1991 Nayak BR, Spiro RG. Localization and structure of the asparagine-linked oligosaccharides of type IV collagen from glomerular basement membrane and lens capsule Journal of Biological Chemistry. 266: 13978-13987. PMID 1856226  0.335
1990 Edge AS, Spiro RG. Characterization of novel sequences containing 3-O-sulfated glucosamine in glomerular basement membrane heparan sulfate and localization of sulfated disaccharides to a peripheral domain. The Journal of Biological Chemistry. 265: 15874-81. PMID 2144291  0.585
1990 Moss J, Woodrow DF, Shore I, Gower P, Phillips M, Spiro RG. Ultrastructural immunogold studies of heparan sulphate proteoglycan in normal human glomeruli and glomerulonephritis Journal of Pathology. 161: 137-143. PMID 2143222 DOI: 10.1002/Path.1711610208  0.316
1990 Edge AS, Kahn CR, Spiro RG. Insulin receptor carbohydrate units contain poly-N-acetyllactosamine chains. Endocrinology. 127: 1887-95. PMID 2119296 DOI: 10.1210/Endo-127-4-1887  0.593
1989 Kato Y, Spiro RG. Characterization of a thyroid sulfotransferase responsible for the 3-O-sulfation of terminal β-D-galactosyl residues in N-linked carbohydrate units Journal of Biological Chemistry. 264: 3364-3371. PMID 2914955  0.353
1988 Spiro MJ, Spiro RG. Biosynthesis of sulfated asparagine-linked complex carbohydrate units of calf thyroglobulin Endocrinology. 123: 56-65. PMID 3383787 DOI: 10.1210/Endo-123-1-56  0.431
1988 Lubas WA, Spiro RG. Evaluation of the role of rat liver golgi endo-α-D-mannosidase in processing N-linked oligosaccharides Journal of Biological Chemistry. 263: 3990-3998. PMID 3346233  0.338
1988 Spiro RG, Bhoyroo VD. Occurrence of sulfate in the asparagine-linked complex carbohydrate units of thyroglobulin. Identification and localization of galactose 3-sulfate and N-acetylglucosamine 6-sulfate residues in the human and calf proteins Journal of Biological Chemistry. 263: 14351-14358. PMID 3170547  0.351
1988 Garlick RL, Bunn HF, Spiro RG. Nonenzymatic glycation of basement membranes from human glomeruli and bovine sources. Effect of diabetes and age Diabetes. 37: 1144-1150. PMID 3134265  0.326
1987 Edge AS, Spiro RG. Selective deglycosylation of the heparan sulfate proteoglycan of bovine glomerular basement membrane and identification of the core protein. The Journal of Biological Chemistry. 262: 6893-8. PMID 2952658  0.586
1987 Shimomura H, Spiro RG. Studies on macromolecular components of human glomerular basement membrane and alterations in diabetes. Decreased levels of heparan sulfate proteoglycan and laminin Diabetes. 36: 374-381. PMID 2948855 DOI: 10.2337/Diab.36.3.374  0.409
1987 Edge AS, Spiro RG. Presence of an O-glycosidically linked hexasaccharide in fetuin. The Journal of Biological Chemistry. 262: 16135-41. PMID 2445744  0.569
1986 Kress BC, Spiro RG. Studies on the glycoprotein nature of the thyrotropin receptor: Interaction with lectins and purification of the bovine protein with the use of Bandeiraea (Griffonia) simplicifolia I affinity chromatography Endocrinology. 118: 974-979. PMID 3004903 DOI: 10.1210/Endo-118-3-974  0.343
1985 Edge AS, Spiro RG. Thyroid cell surface glycoproteins. Nature and disposition of carbohydrate units and evaluation of their blood group I activity. The Journal of Biological Chemistry. 260: 15332-8. PMID 4066673  0.581
1985 Edge AS, Spiro RG. Structural elucidation of glycosaminoglycans through characterization of disaccharides obtained after fragmentation by hydrazine-nitrous acid treatment. Archives of Biochemistry and Biophysics. 240: 560-72. PMID 3927841 DOI: 10.1016/0003-9861(85)90063-3  0.6
1985 Cammarata PR, Spiro RG. Identification of noncollagenous components of calf lens capsule: Evaluation of their adhesion-promoting activity Journal of Cellular Physiology. 125: 393-402. PMID 3905828 DOI: 10.1002/Jcp.1041250306  0.369
1985 Herzberg VL, Grigorescu F, Edge AS, Spiro RG, Kahn CR. Characterization of insulin receptor carbohydrate by comparison of chemical and enzymatic deglycosylation. Biochemical and Biophysical Research Communications. 129: 789-96. PMID 2990467 DOI: 10.1016/0006-291X(85)91961-8  0.599
1984 Edge AS, Spiro RG. Presence of sulfate in N-glycosidically linked carbohydrate units of calf thyroid plasma membrane glycoproteins. The Journal of Biological Chemistry. 259: 4710-3. PMID 6715317  0.586
1984 Chalifour RJ, Spiro RG. Cleavage of dolichyl pyrophosphoryl oligosaccharides by endo-β-N-acetylglucosaminidase H: Comparison of enzymatic and acid hydrolysis techniques for saccharide release Archives of Biochemistry and Biophysics. 229: 386-394. PMID 6422852 DOI: 10.1016/0003-9861(84)90166-8  0.387
1984 Parthasarathy N, Spiro RG. Isolation and characterization of the heparan sulfate proteoglycan of the bovine glomerular basement membrane Journal of Biological Chemistry. 259: 12749-12755. PMID 6238029  0.338
1982 Cammarata PR, Spiro RG. Lens epithelial cell adhesion to lens capsule: A model system for cell-basement membrane interaction Journal of Cellular Physiology. 113: 273-280. PMID 7174730 DOI: 10.1002/Jcp.1041130215  0.308
1982 Parthasarathy N, Spiro RG. Basement membrane glycosaminoglycans: Examination of several membranes and evaluation of the effect of sonic treatment Archives of Biochemistry and Biophysics. 213: 504-511. PMID 7073288 DOI: 10.1016/0003-9861(82)90576-8  0.394
1982 Parthasarathy N, Spiro RG. Effect of diabetes on the glycosaminoglycan component of the human glomerular basement membrane Diabetes. 31: 738-741. PMID 6219021 DOI: 10.2337/Diab.31.8.738  0.365
1982 Spiro RG, Spiro MJ. Studies on the synthesis and processing of the asparagine-linked carbohydrate units of glycoproteins. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 300: 117-127. PMID 6131453 DOI: 10.1098/Rstb.1982.0160  0.394
1980 Kidroni G, Spiro MJ, Spiro RG. Studies on thyroid cell surface glycoproteins: isolation of plasma membranes and characterization of carbohydrate units Archives of Biochemistry and Biophysics. 203: 151-160. PMID 7406497 DOI: 10.1016/0003-9861(80)90163-0  0.399
1980 Kawai Y, Spiro RG. Isolation of the major glycoprotein from fat cell plasma membranes Archives of Biochemistry and Biophysics. 199: 84-91. PMID 7356341 DOI: 10.1016/0003-9861(80)90259-3  0.426
1980 Okada Y, Spiro RG. Isolation and characterization of three major glycoproteins from thyroid plasma membranes Journal of Biological Chemistry. 255: 8865-8872. PMID 6773952  0.325
1979 Brownlee M, Spiro RG. Glomerular basement membrane metabolism in the diabetic rat. In vivo studies Diabetes. 28: 121-125. PMID 421969 DOI: 10.2337/Diab.28.2.121  0.38
1979 Brownlee M, Spiro RG. Biochemistry of the basement membrane in diabetes mellitus. Advances in Experimental Medicine and Biology. 124: 141-156. PMID 388998 DOI: 10.1007/978-1-4684-8508-0_8  0.346
1978 Hoyer JR, Spiro RG. Studies on the rat glomerular basement membrane: Age-related changes in composition Archives of Biochemistry and Biophysics. 185: 496-503. PMID 626506 DOI: 10.1016/0003-9861(78)90194-7  0.333
1978 Spiro RG. Nature of the glycoprotein components of basement membranes Annals of the New York Academy of Sciences. 106-121. PMID 386880 DOI: 10.1111/J.1749-6632.1978.Tb16796.X  0.324
1977 Ito S, Yamashita K, Spiro RG, Kobata A. Structure of a carbohydrate moiety of a unit A glycopeptide of calf thyroglobulin Journal of Biochemistry. 81: 1621-1631. PMID 893367 DOI: 10.1093/Oxfordjournals.Jbchem.A131621  0.329
1976 Spiro RG, Spiro MJ, Bhoyroo VD. Lipid-saccharide intermediates in glycoprotein biosynthesis. II. Studies on the structure of an oligosaccharide-lipid from thyroid. The Journal of Biological Chemistry. 251: 6409-19. PMID 977579  0.308
1976 Sato T, Spiro RG. Studies on the subunit composition of the renal glomerular basement membrane. The Journal of Biological Chemistry. 251: 4062-70. PMID 932022  0.306
1976 Spiro RG. Search for a biochemical basis of diabetic microangiopathy Diabetologia. 12: 1-14. PMID 767187 DOI: 10.1007/Bf01221959  0.344
1973 Beisswenger PJ, Spiro RG. Studies on the human glomerular basement membrane. Composition, nature of the carbohydrate units and chemical changes in diabetes mellitus. Diabetes. 22: 180-93. PMID 4347583 DOI: 10.2337/Diab.22.3.180  0.414
1972 Spiro RG, Spiro MJ. [84] Synthesis of the hydroxylysine-linked carbohydrate units of collagens and basement membranes Methods in Enzymology. 28: 625-637. DOI: 10.1016/0076-6879(72)28087-9  0.347
1971 Spiro RG, Lucas F, Rudall KM. Glycosylation of hydroxylysine in collagens. Nature: New Biology. 231: 54-5. PMID 5283389 DOI: 10.1038/Newbio231054A0  0.314
1971 Spiro RG, Spiro MJ. Effect of diabetes on the biosynthesis of the renal glomerular basement membrane. Studies on the glucosyltransferase Diabetes. 20: 641-648. PMID 5110695 DOI: 10.2337/Diab.20.10.641  0.369
1970 Beisswenger PJ, Spiro RG. Human glomerular basement membrane: Chemical alteration in diabetes mellitus Science. 168: 596-598. PMID 5436594 DOI: 10.1126/Science.168.3931.596  0.381
1958 SPIRO RG, ASHMORE J, HASTINGS AB. Studies on carbohydrate metabolism in rat liver slices. XII. Sequence of metabolic events following acute insulin deprivation. The Journal of Biological Chemistry. 230: 761-71. PMID 13525393  0.414
1958 SPIRO RG, HASTINGS AB. Studies on carbohydrate metabolism in rat liver slices. XI. Effect of prolonged insulin administration to the alloxan-diabetic animal. The Journal of Biological Chemistry. 230: 751-9. PMID 13525392  0.434
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