Lei Cao, PhD - Publications

Molecular Virology, Immunology, and Molecular Genetics Ohio State University, Columbus, Columbus, OH 
Neuroscience, Cancer, Gene therapy, Virology, Metabolism

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Queen NJ, Boardman AA, Patel RS, Siu JJ, Mo X, Cao L. Environmental enrichment improves metabolic and behavioral health in the BTBR mouse model of autism. Psychoneuroendocrinology. 111: 104476. PMID 31648110 DOI: 10.1016/j.psyneuen.2019.104476  0.52
2019 Zhao F, Siu JJ, Huang W, Askwith C, Cao L. Insulin Modulates Excitatory Synaptic Transmission and Synaptic Plasticity in the Mouse Hippocampus. Neuroscience. PMID 31146008 DOI: 10.1016/j.neuroscience.2019.05.033  0.52
2019 Ali S, Liu X, Queen NJ, Patel RS, Wilkins RK, Mo X, Cao L. Long-term environmental enrichment affects microglial morphology in middle age mice. Aging. PMID 31039130 DOI: 10.18632/aging.101923  0.52
2019 Foglesong G, Queen N, Huang W, Widstrom K, Cao L. Enriched environment inhibits breast cancer progression in obese models with intact leptin signaling. Endocrine-Related Cancer. PMID 30856610 DOI: 10.1530/ERC-19-0075  0.44
2019 Xiao R, Mansour AG, Huang W, Chrislip LA, Wilkins RK, Queen NJ, Youssef Y, Mao HC, Caligiuri MA, Cao L. Adipocytes: A Novel Target for IL-15/IL-15Rα Cancer Gene Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30833178 DOI: 10.1016/j.ymthe.2019.02.011  0.52
2019 Huang W, Queen NJ, Cao L. rAAV-Mediated Gene Delivery to Adipose Tissue. Methods in Molecular Biology (Clifton, N.J.). 1950: 389-405. PMID 30783987 DOI: 10.1007/978-1-4939-9139-6_23  0.52
2018 McMurphy T, Huang W, Liu X, Siu JJ, Queen NJ, Xiao R, Cao L. Hypothalamic gene transfer of BDNF promotes healthy aging in mice. Aging Cell. e12846. PMID 30585393 DOI: 10.1111/acel.12846  0.52
2018 Shao P, Guo N, Wang C, Zhao M, Yi L, Liu C, Kang L, Cao L, Lv P, Xing L, Zhang X, Shen H. Aflatoxin G induced TNF-α-dependent lung inflammation to enhance DNA damage in alveolar epithelial cells. Journal of Cellular Physiology. PMID 30478833 DOI: 10.1002/jcp.27596  0.32
2018 Xiao R, Bergin SM, Huang W, Mansour AG, Liu X, Judd RT, Widstrom KJ, Queen N, Wilkins R, Siu JJ, Ali S, Caligiuri MA, Cao L. Enriched environment regulates thymocyte development and alleviates experimental autoimmune encephalomyelitis in mice. Brain, Behavior, and Immunity. PMID 30287389 DOI: 10.1016/j.bbi.2018.09.028  0.52
2018 Liu F, Zhou H, Cao L, Guo Z, Dong C, Yu L, Wang Y, Liu C, Qiu J, Xue Y, Liu X, Xu Y. Risk of reduced platelet counts in patients with nonalcoholic fatty liver disease (NAFLD): a prospective cohort study. Lipids in Health and Disease. 17: 221. PMID 30227874 DOI: 10.1186/s12944-018-0865-7  0.44
2018 McMurphy T, Huang W, Queen NJ, Ali S, Widstrom KJ, Liu X, Xiao R, Siu JJ, Cao L. Implementation of environmental enrichment after middle age promotes healthy aging. Aging. PMID 30036185 DOI: 10.18632/aging.101502  0.52
2017 Siu JJ, Queen NJ, Liu X, Huang W, McMurphy T, Cao L. Molecular Therapy of Melanocortin-4-Receptor Obesity by an Autoregulatory BDNF Vector. Molecular Therapy. Methods & Clinical Development. 7: 83-95. PMID 29296625 DOI: 10.1016/j.omtm.2017.09.005  0.52
2017 Huang W, Liu X, Queen NJ, Cao L. Targeting Visceral Fat by Intraperitoneal Delivery of Novel AAV Serotype Vector Restricting Off-Target Transduction in Liver. Molecular Therapy. Methods & Clinical Development. 6: 68-78. PMID 28702474 DOI: 10.1016/j.omtm.2017.06.002  0.52
2017 Zhang Y, Xie L, Gunasekar SK, Tong D, Mishra A, Gibson WJ, Wang C, Fidler T, Marthaler B, Klingelhutz A, Abel ED, Samuel I, Smith JK, Cao L, Sah R. Erratum: SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis. Nature Cell Biology. 19: 873. PMID 28659636 DOI: 10.1038/ncb3556  0.32
2017 Zhang Y, Xie L, Gunasekar SK, Tong D, Mishra A, Gibson WJ, Wang C, Fidler T, Marthaler B, Klingelhutz A, Abel ED, Samuel I, Smith JK, Cao L, Sah R. Erratum: SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis. Nature Cell Biology. 19: 740. PMID 28561048 DOI: 10.1038/ncb3536  0.32
2017 Zhang Y, Xie L, Gunasekar SK, Tong D, Mishra A, Gibson WJ, Wang C, Fidler T, Marthaler B, Klingelhutz A, Dale Abel E, Samuel I, Smith JK, Cao L, Sah R. SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis. Nature Cell Biology. PMID 28436964 DOI: 10.1038/ncb3514  0.32
2016 Xiao R, Bergin SM, Zhang M, Cao L. Anticancer Molecules in Brain: Implication for Novel Strategy for Cancer Immunotherapy. Immunotherapy (Los Angeles, Calif.). 2. PMID 28299372 DOI: 10.4172/2471-9552.1000e104  0.44
2016 McMurphy TB, Huang W, Xiao R, Liu X, Dhurandhar NV, Cao L. Hepatic Expression of Adenovirus 36 E4ORF1 Improves Glycemic Control and Promotes Glucose Metabolism via AKT Activation. Diabetes. PMID 27903748 DOI: 10.2337/db16-0876  0.44
2016 Ou Z, Sun Y, Lin L, You N, Liu X, Li H, Ma Y, Cao L, Han Y, Liu M, Deng Y, Yao L, Lu QR, Chen Y. Olig2-Targeted G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Survival in Response to Lysolecithin-Induced Demyelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 10560-10573. PMID 27733608 DOI: 10.1523/JNEUROSCI.0898-16.2016  0.44
2016 Zhu Y, Gao Y, Tao C, Shao M, Zhao S, Huang W, Yao T, Johnson JA, Liu T, Cypess AM, Gupta O, Holland WL, Gupta RK, Spray DC, Tanowitz HB, ... Cao L, et al. Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals. Cell Metabolism. 24: 420-433. PMID 27626200 DOI: 10.1016/j.cmet.2016.08.005  0.44
2016 Xiao R, Bergin SM, Huang W, Slater AM, Liu X, Judd RT, Lin ED, Widstrom KJ, Scoville SD, Yu J, Caligiuri M, Cao L. Environmental and genetic activation of hypothalamic BDNF modulates T-cell immunity to exert an anticancer phenotype. Cancer Immunology Research. PMID 27045020 DOI: 10.1158/2326-6066.CIR-15-0297  0.92
2016 Ke Z, Zhang X, Cao Z, Ding Y, Li N, Cao L, Wang T, Zhang C, Ding G, Wang Z, Xu X, Xiao W. Drug discovery of neurodegenerative disease through network pharmacology approach in herbs. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 78: 272-9. PMID 26898452 DOI: 10.1016/j.biopha.2016.01.021  0.48
2016 Huang W, McMurphy T, Liu X, Wang C, Cao L. Genetic manipulation of brown fat via oral administration of an engineered recombinant adeno-associated viral serotype vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26857843 DOI: 10.1038/mt.2016.34  0.44
2016 Wang HF, Tan L, Cao L, Zhu XC, Jiang T, Tan MS, Liu Y, Wang C, Tsai RM, Jia JP, Yu JT. Application of the IWG-2 Diagnostic Criteria for Alzheimer's Disease to the ADNI. Journal of Alzheimer's Disease : Jad. PMID 26836176 DOI: 10.3233/JAD-150824  0.32
2016 Wang X, Lu T, Wen J, Xu L, Zeng D, Wu Q, Cao L, Lin S, Liu X, Jiang X. Selective responses of human gingival fibroblasts and bacteria on carbon fiber reinforced polyetheretherketone with multilevel nanostructured TiO2. Biomaterials. 83: 207-218. PMID 26774566 DOI: 10.1016/j.biomaterials.2016.01.001  0.44
2016 Foglesong GD, Huang W, Liu X, Slater AM, Siu J, Yildiz V, Salton SR, Cao L. Role of Hypothalamic VGF in Energy Balance and Metabolic Adaption to Environmental Enrichment in Mice. Endocrinology. en20151627. PMID 26730934 DOI: 10.1210/en.2015-1627  0.92
2016 Zheng X, Wang W, Liu S, Wu J, Li F, Cao L, Liu XD, Mo X, Fan C. Enhancement of chondrogenic differentiation of rabbit mesenchymal stem cells by oriented nanofiber yarn-collagen type I/hyaluronate hybrid. Materials Science & Engineering. C, Materials For Biological Applications. 58: 1071-6. PMID 26478405 DOI: 10.1016/j.msec.2015.07.066  0.52
2016 Cao LZ, Liu X, Zhao JQ, Yang Y, Li YD, Wang XQ, Lu HX. Evolutions of two-qubit entangled system in different noisy environments and channels Wuli Xuebao/Acta Physica Sinica. 65. DOI: 10.7498/aps.65.030303  0.44
2016 Chen Z, Wang C, Luo H, Wang H, Chen Y, Wen C, Yu Y, Cao L, Li J. Vehicle Detection in High-Resolution Aerial Images Based on Fast Sparse Representation Classification and Multiorder Feature Ieee Transactions On Intelligent Transportation Systems. DOI: 10.1109/TITS.2016.2517826  0.32
2016 Liu X, Cao L, Sun W, Zhou Z, Yang J. A P/N type compounded Cu2O/TiO2 photo-catalytic membrane for organic pollutant degradation Research On Chemical Intermediates. 1-12. DOI: 10.1007/s11164-016-2461-7  0.44
2015 Jiang YP, Wu X, Li N, Cao L, Ding G, Wang ZZ, Xiao W. [Research on immune-modulation effects and its mechanisms of Guizhi Fuling capsule and its active ingredient combination]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 40: 3068-71. PMID 26677713  0.48
2015 Ke ZP, Zhang XZ, Ding Y, Cao L, Li N, Ding G, Wang ZZ, Xiao W. [Study on effective substance basis and molecular mechanism of Qigui Tongfeng tablet using network pharmacology method]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 40: 2837-42. PMID 26666036  0.48
2015 Cao ZY, Ding Y, Su ZZ, Li N, Cao L, Ding G, Wang ZZ, Xiao W. [Study on contribution of main components in Guizhi Fuling capsule based on molecular imprinting technique and activity screening]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 40: 2420-7. PMID 26591536  0.48
2015 Shan Y, Wang DD, Xu YX, Wang C, Cao L, Liu YS, Zhu CQ. Aging as a Precipitating Factor in Chronic Restraint Stress-Induced Tau Aggregation Pathology, and the Protective Effects of Rosmarinic Acid. Journal of Alzheimer's Disease : Jad. PMID 26577520 DOI: 10.3233/JAD-150486  0.32
2015 Heng QQ, Cao L, Li N, Ding G, Wang ZZ, Xiao W. [Effect of Guizhi Fuling capsule and combination of active ingredients on rats with uterine myoma]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 40: 2206-9. PMID 26552182 DOI: 10.4268/cjcmm20151126  0.48
2015 Meng F, Li S, Cao L, Peng Q, Li M, Wang C, Zhang W. Designing Fatigue Warning Systems: The perspective of professional drivers. Applied Ergonomics. PMID 26482894 DOI: 10.1016/j.apergo.2015.08.003  0.32
2015 Zhang X, Ren X, Zhang Q, Li Z, Ma S, Bao J, Li Z, Bai X, Zheng L, Zhang Z, Shang S, Zhang C, Wang C, Cao L, Wang Q, et al. PGC-1α/ERRα-Sirt3 pathway regulates DAergic neuronal death by directly deacetylating SOD2 and ATP synthase β. Antioxidants & Redox Signaling. PMID 26421366 DOI: 10.1089/ars.2015.6403  0.32
2015 Li C, Kan L, Chen Y, Zheng X, Li W, Zhang W, Cao L, Lin X, Ji S, Huang S, Zhang G, Liu X, Tao Y, Wu S, Chen D. Ci antagonizes Hippo signaling in the somatic cells of the ovary to drive germline stem cell differentiation. Cell Research. PMID 26403189 DOI: 10.1038/cr.2015.114  0.44
2015 Slater AM, Cao L. A Protocol for Housing Mice in an Enriched Environment. Journal of Visualized Experiments : Jove. e52874. PMID 26131694 DOI: 10.3791/52874  0.92
2015 Wang G, Song Y, Liu T, Wang C, Zhang Q, Liu F, Cai X, Miao Z, Xu H, Xu H, Cao L, Li F. PAK1-mediated MORC2 phosphorylation promotes gastric tumorigenesis. Oncotarget. 6: 9877-86. PMID 25888627  0.32
2015 Zhu XC, Tan L, Wang HF, Jiang T, Cao L, Wang C, Wang J, Tan CC, Meng XF, Yu JT. Rate of early onset Alzheimer's disease: a systematic review and meta-analysis. Annals of Translational Medicine. 3: 38. PMID 25815299 DOI: 10.3978/j.issn.2305-5839.2015.01.19  0.32
2015 Wang C, Dong X, Zhou F, Cao L, Chi CH. Coupled attribute similarity learning on categorical data. Ieee Transactions On Neural Networks and Learning Systems. 26: 781-97. PMID 25794382 DOI: 10.1109/TNNLS.2014.2325872  0.32
2015 During MJ, Liu X, Huang W, Magee D, Slater A, McMurphy T, Wang C, Cao L. Adipose VEGF Links the White-to-Brown Fat Switch With Environmental, Genetic, and Pharmacological Stimuli in Male Mice. Endocrinology. 156: 2059-73. PMID 25763639 DOI: 10.1210/en.2014-1905  0.92
2015 Zhu XC, Yu Y, Wang HF, Jiang T, Cao L, Wang C, Wang J, Tan CC, Meng XF, Tan L, Yu JT. Physiotherapy intervention in Alzheimer's disease: systematic review and meta-analysis. Journal of Alzheimer's Disease : Jad. 44: 163-74. PMID 25201787 DOI: 10.3233/JAD-141377  0.32
2014 Liu X, Magee D, Wang C, McMurphy T, Slater A, During M, Cao L. Adipose tissue insulin receptor knockdown via a new primate-derived hybrid recombinant AAV serotype. Molecular Therapy. Methods & Clinical Development. 1. PMID 25383359 DOI: 10.1038/mtm.2013.8  0.48
2014 Liu DX, Wang J, Pan K, Qiu J, Canova M, Cao LR, Co AC. In situ quantification and visualization of lithium transport with neutrons. Angewandte Chemie (International Ed. in English). 53: 9498-502. PMID 25044527 DOI: 10.1002/anie.201404197  1
2014 Liu X, Mcmurphy T, Xiao R, Slater A, Huang W, Cao L. Hypothalamic gene transfer of BDNF inhibits breast cancer progression and metastasis in middle age obese mice Molecular Therapy. 22: 1275-1284. PMID 24637454 DOI: 10.1038/mt.2014.45  0.92
2014 McMurphy T, Xiao R, Magee D, Slater A, Zabeau L, Tavernier J, Cao L. The anti-tumor activity of a neutralizing nanobody targeting leptin receptor in a mouse model of melanoma Plos One. 9. PMID 24587106 DOI: 10.1371/journal.pone.0089895  0.92
2012 Mulligan PL, Cao LR, Turkoglu D. A multi-detector, digitizer based neutron depth profiling device for characterizing thin film materials. The Review of Scientific Instruments. 83: 073303. PMID 22852681 DOI: 10.1063/1.4732168  1
2012 Cao L, During MJ. What is the brain-cancer connection? Annual Review of Neuroscience. 35: 331-45. PMID 22462541 DOI: 10.1146/annurev-neuro-062111-150546  0.92
2011 Cao L, Choi EY, Liu X, Martin A, Wang C, Xu X, During MJ. White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis. Cell Metabolism. 14: 324-38. PMID 21907139 DOI: 10.1016/j.cmet.2011.06.020  0.92
2010 Cao L, Liu X, Lin EJ, Wang C, Choi EY, Riban V, Lin B, During MJ. Environmental and genetic activation of a brain-adipocyte BDNF/leptin axis causes cancer remission and inhibition. Cell. 142: 52-64. PMID 20603014 DOI: 10.1016/j.cell.2010.05.029  0.92
2009 Cao L, Lin EJ, Cahill MC, Wang C, Liu X, During MJ. Molecular therapy of obesity and diabetes by a physiological autoregulatory approach. Nature Medicine. 15: 447-54. PMID 19270710 DOI: 10.1038/nm.1933  0.92
2006 During MJ, Cao L. VEGF, a mediator of the effect of experience on hippocampal neurogenesis. Current Alzheimer Research. 3: 29-33. PMID 16472200 DOI: 10.2174/156720506775697133  0.92
2004 Cao L, Jiao X, Zuzga DS, Liu Y, Fong DM, Young D, During MJ. VEGF links hippocampal activity with neurogenesis, learning and memory. Nature Genetics. 36: 827-35. PMID 15258583 DOI: 10.1038/ng1395  0.92
2003 Zhuo M, Xu DH, Cao L, Xu LF, Yu FR, Zheng ZC, Liu XY. Long term gene therapy of Parkinson's disease using immortalized rat glial cell line with tyrosine hydroxylase gene. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao Acta Biochimica Et Biophysica Sinica. 35: 1066-71. PMID 14673496  0.92
2003 During MJ, Cao L, Zuzga DS, Francis JS, Fitzsimons HL, Jiao X, Bland RJ, Klugmann M, Banks WA, Drucker DJ, Haile CN. Glucagon-like peptide-1 receptor is involved in learning and neuroprotection. Nature Medicine. 9: 1173-9. PMID 12925848 DOI: 10.1038/nm919  0.92
2002 Cao L, During M, Xiao W. Replication competent helper functions for recombinant AAV vector generation. Gene Therapy. 9: 1199-206. PMID 12215886 DOI: 10.1038/sj.gt.3301710  0.92
2001 Xu DH, Chen XW, Xu LF, Cao L, Chen SD, Liu XY, Zheng ZC. Treatment of Parkinson's disease by genetically modified immortalized fibroblasts Acta Biochimica Et Biophysica Sinica. 33: 121-122.  0.92
2000 Cao L, Liu Y, During MJ, Xiao W. High-titer, wild-type free recombinant adeno-associated virus vector production using intron-containing helper plasmids. Journal of Virology. 74: 11456-63. PMID 11090141 DOI: 10.1128/JVI.74.24.11456-11463.2000  0.92
2000 Cao L, Zhao YC, Jiang ZH, Xu DH, Liu ZG, Chen SD, Liu XY, Zheng ZC. Long-term phenotypic correction of rodent hemiparkinsonism by gene therapy using genetically modified myoblasts Gene Therapy. 7: 445-449. PMID 10694827  0.92
2000 Xu DH, Xu LF, Shi CG, Zhuo M, Cao L, Liu XY, Zheng ZC. Adenovirus-mediated th gene therapy of parkinson's disease in experimental rat model Acta Biochimica Et Biophysica Sinica. 32: 349-350.  0.92
1999 Cao L, Rosenthal F, Jiao XY, Tanczos E, Mertelsmann R, Stark GB, Kulmburg P. Continuous delivery of epidermal growth factor to wounds in vivo by genetically modified fibroblasts transfected with a novel chimeric construct Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi = Zhongguo Xiufu Chongjian Waike Zazhi = Chinese Journal of Reparative and Reconstructive Surgery. 13: 263-269. PMID 12080815  0.92
1997 Jiang ZH, Ni ZM, Zhou CF, Cao L, Zheng ZC, Liu XY, Zhao YC, Chen SD. [Expression of foreign tyrosine hydroxylase gene in the rat model of Parkinson's disease]. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 49: 141-5. PMID 9812848  0.92
1995 Cao L, Zheng ZC, Zha YC, Jiang ZH, Liu ZG, Chen SD, Zhou CF, Liu XY. Gene therapy of Parkinson disease model rat by direct injection of plasmid DNA-lipofectin complex Human Gene Therapy. 6: 1497-1501. PMID 8573622  0.92
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