Risheng Xu, MD/PhD - Publications

Affiliations: 
2003-2007 Chemistry Harvard College 
 2007-2015 Pharmacology Johns Hopkins University School of Medicine, Baltimore, MD, United States 
 2015-2022 Neurosurgery Johns Hopkins University School of Medicine, Baltimore, MD, United States 

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Rao F, Cha J, Xu J, Xu R, Vandiver MS, Tyagi R, Tokhunts R, Koldobskiy MA, Fu C, Barrow R, Wu M, Fiedler D, Barrow JC, Snyder SH. Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2. Molecular Cell. 79: 702. PMID 32822581 DOI: 10.1016/j.molcel.2020.07.021  1
2019 Vasavda C, Kothari R, Malla AP, Tokhunts R, Lin A, Ji M, Ricco C, Xu R, Saavedra HG, Sbodio JI, Snowman AM, Albacarys L, Hester L, Sedlak TW, Paul BD, et al. Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide. Cell Chemical Biology. PMID 31353321 DOI: 10.1016/J.Chembiol.2019.07.006  1
2019 Guha P, Tyagi R, Chowdhury S, Reilly L, Fu C, Xu R, Resnick AC, Snyder SH. IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration. Cell Reports. 26: 2692-2703.e7. PMID 30840891 DOI: 10.1016/J.Celrep.2019.02.013  1
2017 Fu C, Tyagi R, Chin AC, Rojas T, Li RJ, Guha P, Bernstein IA, Rao F, Xu R, Cha JY, Xu J, Snowman AM, Semenza GL, Snyder SH. Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation. Circulation Research. PMID 29279301 DOI: 10.1161/Circresaha.117.311983  1
2016 Yang W, Porras JL, Garzon-Muvdi T, Xu R, Caplan JM, Hung AL, Braileanu M, Rong X, Colby GP, Coon AL, Tamargo RJ, Huang J. Management Outcome of Brainstem Arteriovenous Malformations (AVMs): The Role of Radiosurgery. World Neurosurgery. PMID 27368509 DOI: 10.1016/J.Wneu.2016.06.082  1
2015 Ahmed I, Sbodio JI, Harraz MM, Tyagi R, Grima JC, Albacarys LK, Hubbi ME, Xu R, Kim S, Paul BD, Snyder SH. Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase. Proceedings of the National Academy of Sciences of the United States of America. 112: 9751-6. PMID 26195796 DOI: 10.1073/Pnas.1511810112  1
2015 Liu J, Deng H, Long X, Chen X, Xu R, Liu Z. A comparative study of perioperative complications between transforaminal versus posterior lumbar interbody fusion in degenerative lumbar spondylolisthesis. European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. PMID 26126415 DOI: 10.1007/s00586-015-4086-8  1
2015 Rao F, Xu J, Fu C, Cha JY, Gadalla MM, Xu R, Barrow JC, Snyder SH. Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1. Proceedings of the National Academy of Sciences of the United States of America. 112: 1773-8. PMID 25617365 DOI: 10.1073/Pnas.1424642112  0.64
2015 Ahmed I, Sbodio JI, Harraz MM, Tyagi R, Grima JC, Albacarys LK, Hubbi ME, Xu R, Kim S, Paul BD, Snyder SH. Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase Proceedings of the National Academy of Sciences of the United States of America. 112: 9751-9756. DOI: 10.1073/pnas.1511810112  1
2014 Rao F, Xu J, Khan AB, Gadalla MM, Cha JY, Xu R, Tyagi R, Dang Y, Chakraborty A, Snyder SH. Inositol hexakisphosphate kinase-1 mediates assembly/disassembly of the CRL4-signalosome complex to regulate DNA repair and cell death. Proceedings of the National Academy of Sciences of the United States of America. 111: 16005-10. PMID 25349427 DOI: 10.1073/Pnas.1417900111  1
2014 Xu R, Bydon M, Macki M, Belkoff SM, Langdale ER, McGovern K, Wolinsky JP, Gokalsan ZL, Bydon A. Biomechanical impact of C2 pedicle screw length in an atlantoaxial fusion construct. Surgical Neurology International. 5: S343-6. PMID 25289157 DOI: 10.4103/2152-7806.139664  1
2014 Paul BD, Sbodio JI, Xu R, Vandiver MS, Cha JY, Snowman AM, Snyder SH. Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease. Nature. 509: 96-100. PMID 24670645 DOI: 10.1038/Nature13136  1
2014 Rao F, Cha J, Xu J, Xu R, Vandiver MS, Tyagi R, Tokhunts R, Koldobskiy MA, Fu C, Barrow R, Wu M, Fiedler D, Barrow JC, Snyder SH. Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2. Molecular Cell. 54: 119-32. PMID 24657168 DOI: 10.1016/J.Molcel.2014.02.020  1
2014 Bydon M, Macki M, Xu R, Ain MC, Ahn ES, Jallo GI. Spinal decompression in achondroplastic patients using high-speed drill versus ultrasonic bone curette: Technical note and outcomes in 30 cases Journal of Pediatric Orthopaedics. DOI: 10.1097/BPO.0000000000000211  1
2013 Xu R, Paul BD, Smith DR, Tyagi R, Rao F, Khan AB, Blech DJ, Vandiver MS, Harraz MM, Guha P, Ahmed I, Sen N, Gallagher M, Snyder SH. Inositol polyphosphate multikinase is a transcriptional coactivator required for immediate early gene induction. Proceedings of the National Academy of Sciences of the United States of America. 110: 16181-6. PMID 24043835 DOI: 10.1073/Pnas.1315551110  1
2013 Roppenser B, Kwon H, Canadien V, Xu R, Devreotes PN, Grinstein S, Brumell JH. Multiple host kinases contribute to Akt activation during Salmonella infection. Plos One. 8: e71015. PMID 23990921 DOI: 10.1371/Journal.Pone.0071015  1
2013 Xu R, Serritella AV, Sen T, Farook JM, Sedlak TW, Baraban J, Snyder SH, Sen N. Behavioral effects of cocaine mediated by nitric oxide-GAPDH transcriptional signaling. Neuron. 78: 623-30. PMID 23719162 DOI: 10.1016/j.neuron.2013.03.021  1
2013 Xu R, Snyder SH. Gene transcription by p53 requires inositol polyphosphate multikinase as a co-activator. Cell Cycle (Georgetown, Tex.). 12: 1819-20. PMID 23708509 DOI: 10.4161/cc.25119  1
2013 Xu R, Sen N, Paul BD, Snowman AM, Rao F, Vandiver MS, Xu J, Snyder SH. Inositol polyphosphate multikinase is a coactivator of p53-mediated transcription and cell death. Science Signaling. 6: ra22. PMID 23550211 DOI: 10.1126/Scisignal.2003405  1
2013 Vandiver MS, Paul BD, Xu R, Karuppagounder S, Rao F, Snowman AM, Ko HS, Lee YI, Dawson VL, Dawson TM, Sen N, Snyder SH. Sulfhydration mediates neuroprotective actions of parkin. Nature Communications. 4: 1626. PMID 23535647 DOI: 10.1038/Ncomms2623  1
2013 Xu R, Serritella A, Sen T, Farook J, Sedlak T, Baraban J, Snyder S, Sen N. Behavioral Effects of Cocaine Mediated by Nitric Oxide-GAPDH Transcriptional Signaling Neuron. 79: 206. DOI: 10.1016/j.neuron.2013.06.032  1
2012 Sen N, Paul BD, Gadalla MM, Mustafa AK, Sen T, Xu R, Kim S, Snyder SH. Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions. Molecular Cell. 45: 13-24. PMID 22244329 DOI: 10.1016/J.Molcel.2011.10.021  1
2011 Maag D, Maxwell MJ, Hardesty DA, Boucher KL, Choudhari N, Hanno AG, Ma JF, Snowman AS, Pietropaoli JW, Xu R, Storm PB, Saiardi A, Snyder SH, Resnick AC. Inositol polyphosphate multikinase is a physiologic PI3-kinase that activates Akt/PKB. Proceedings of the National Academy of Sciences of the United States of America. 108: 1391-6. PMID 21220345 DOI: 10.1073/Pnas.1017831108  1
2010 Xu R, McGirt MJ, Sutter EG, Sciubba DM, Wolinsky JP, Witham TF, Gokaslan ZL, Bydon A. Biomechanical comparison between C-7 lateral mass and pedicle screws in subaxial cervical constructs. Presented at the 2009 Joint Spine Meeting. Laboratory investigation. Journal of Neurosurgery. Spine. 13: 688-94. PMID 21121745 DOI: 10.3171/2010.5.Spine09712  1
2010 Bydon A, Xu R, Parker SL, McGirt MJ, Bydon M, Gokaslan ZL, Witham TF. Recurrent back and leg pain and cyst reformation after surgical resection of spinal synovial cysts: Systematic review of reported postoperative outcomes Spine Journal. 10: 820-826. PMID 20488765 DOI: 10.1016/J.Spinee.2010.04.010  1
2010 Xu R, McGirt MJ, Parker SL, Bydon M, Olivi A, Wolinsky JP, Witham TF, Gokaslan ZL, Bydon A. Factors associated with recurrent back pain and cyst recurrence after surgical resection of one hundred ninety-five spinal synovial cysts: Analysis of one hundred sixty-seven consecutive cases Spine. 35: 1044-1053. PMID 20173680 DOI: 10.1097/Brs.0B013E3181Bdafed  1
2010 Parker SL, Xu R, McGirt MJ, Witham TF, Long DM, Bydon A. Long-term back pain after a single-level discectomy for radiculopathy: Incidence and health care cost analysis - Clinical article Journal of Neurosurgery: Spine. 12: 178-182. PMID 20121353 DOI: 10.3171/2009.9.SPINE09410  1
2009 McGirt MJ, Sutter EG, Xu R, Sciubba DM, Wolinsky JP, Witham TF, Gokaslan ZL, Bydon A. Biomechanical comparison of translaminar versus pedicle screws at T1 and T2 in long subaxial cervical constructs. Neurosurgery. 65: 167-72; discussion 1. PMID 19934991 DOI: 10.1227/01.Neu.0000345642.50726.A3  1
2007 Evans DA, Fandrick KR, Song HJ, Scheidt KA, Xu R. Enantioselective Friedel-Crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes. Journal of the American Chemical Society. 129: 10029-41. PMID 17658808 DOI: 10.1021/Ja072976I  0.92
2007 Evans DA, Nagorny P, McRae KJ, Reynolds DJ, Sonntag LS, Vounatsos F, Xu R. Enantioselective synthesis of oasomycin a, part I: synthesis of the C1-C12 and C13-C28 subunits. Angewandte Chemie (International Ed. in English). 46: 537-40. PMID 17154211 DOI: 10.1002/Anie.200603653  0.92
2006 Evans DA, Nagorny P, Xu R. Ceric ammonium nitrate promoted oxidation of oxazoles. Organic Letters. 8: 5669-71. PMID 17107099 DOI: 10.1021/Ol0624530  0.92
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