Joachim Wittbrodt - Publications

EMBL/University of Heidelberg, Heidelberg, Baden-Württemberg, Germany 

138 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Meyer HV, Dawes TJW, Serrani M, Bai W, Tokarczuk P, Cai J, de Marvao A, Henry A, Lumbers RT, Gierten J, Thumberger T, Wittbrodt J, Ware JS, Rueckert D, Matthews PM, et al. Genetic and functional insights into the fractal structure of the heart. Nature. PMID 32814899 DOI: 10.1038/s41586-020-2635-8  0.36
2020 Gierten J, Pylatiuk C, Hammouda OT, Schock C, Stegmaier J, Wittbrodt J, Gehrig J, Loosli F. Automated high-throughput heartbeat quantification in medaka and zebrafish embryos under physiological conditions. Scientific Reports. 10: 2046. PMID 32029752 DOI: 10.1038/s41598-020-58563-w  0.6
2018 Weinhardt V, Shkarin R, Wernet T, Wittbrodt J, Baumbach T, Loosli F. Quantitative morphometric analysis of adult teleost fish by X-ray computed tomography. Scientific Reports. 8: 16531. PMID 30410001 DOI: 10.1038/s41598-018-34848-z  0.6
2017 Mateo JL, van den Berg DLC, Haeussler M, Drechsel D, Gaber ZB, Castro DS, Robson P, Lu QR, Crawford GE, Flicek P, Ettwiller L, Wittbrodt J, Guillemot F, Martynoga B. Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal. Genome Research. 27: 2129. PMID 29196563 DOI: 10.1101/gr.231845.117  0.36
2017 Pereiro L, Loosli F, Fernández J, Härtel S, Wittbrodt J, Concha ML. Gastrulation in an annual killifish: Molecular and cellular events during germ layer formation in Austrolebias. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 28249357 DOI: 10.1002/dvdy.24496  0.6
2016 Mateo JL, van den Berg DL, Haeussler M, Drechsel D, Gaber ZB, Castro DS, Robson P, Lu QR, Crawford GE, Flicek P, Ettwiller L, Wittbrodt J, Guillemot F, Martynoga B. Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal. Genome Research. 26: 1626. PMID 27803196 DOI: 10.1101/gr.216044.116  0.36
2016 Aghaallaei N, Gruhl F, Schaefer CQ, Wernet T, Weinhardt V, Centanin L, Loosli F, Baumbach T, Wittbrodt J. Identification, visualization and clonal analysis of intestinal stem cells in fish. Development (Cambridge, England). PMID 27578784 DOI: 10.1242/dev.134098  0.6
2016 Kromm D, Thumberger T, Wittbrodt J. An eye on light-sheet microscopy Methods in Cell Biology. DOI: 10.1016/bs.mcb.2016.01.001  1
2015 Dolle D, Mateo JL, Eichenlaub MP, Sinn R, Reinhardt R, Höckendorf B, Inoue D, Centanin L, Ettwiller L, Wittbrodt J. Handling Permutation in Sequence Comparison: Genome-Wide Enhancer Prediction in Vertebrates by a Novel Non-Linear Alignment Scoring Principle. Plos One. 10: e0141487. PMID 26505748 DOI: 10.1371/Journal.Pone.0141487  1
2015 Hameed LS, Berg DA, Belnoue L, Jensen LD, Cao Y, Simon A. Environmental changes in oxygen tension reveal ROS-dependent neurogenesis and regeneration in the adult newt brain. Elife. 4. PMID 26485032 DOI: 10.7554/Elife.08422  1
2015 Zhang P, Kratz AS, Salama M, Elabd S, Heinrich T, Wittbrodt J, Blattner C, Davidson G. Expression screening using a Medaka cDNA library identifies evolutionarily conserved regulators of the p53/Mdm2 pathway. Bmc Biotechnology. 15: 92. PMID 26450685 DOI: 10.1186/s12896-015-0208-y  1
2015 Bajoghli B, Kuri P, Inoue D, Aghaallaei N, Hanelt M, Thumberger T, Rauzi M, Wittbrodt J, Leptin M. Noninvasive In Toto Imaging of the Thymus Reveals Heterogeneous Migratory Behavior of Developing T Cells. Journal of Immunology (Baltimore, Md. : 1950). 195: 2177-86. PMID 26188059 DOI: 10.4049/jimmunol.1500361  1
2015 Auer TO, Xiao T, Bercier V, Gebhardt C, Duroure K, Concordet JP, Wyart C, Suster M, Kawakami K, Wittbrodt J, Baier H, Del Bene F. Deletion of a kinesin I motor unmasks a mechanism of homeostatic branching control by neurotrophin-3. Elife. 4. PMID 26076409 DOI: 10.7554/Elife.05061  1
2015 Stemmer M, Thumberger T, Del Sol Keyer M, Wittbrodt J, Mateo JL. CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool. Plos One. 10: e0124633. PMID 25909470 DOI: 10.1371/journal.pone.0124633  1
2015 Reinhardt R, Centanin L, Tavhelidse T, Inoue D, Wittbrodt B, Concordet JP, Martinez-Morales JR, Wittbrodt J. Sox2, Tlx, Gli3, and Her9 converge on Rx2 to define retinal stem cells in vivo. The Embo Journal. 34: 1572-88. PMID 25908840 DOI: 10.15252/embj.201490706  1
2015 Kirchmaier S, Naruse K, Wittbrodt J, Loosli F. The genomic and genetic toolbox of the teleost medaka (Oryzias latipes). Genetics. 199: 905-18. PMID 25855651 DOI: 10.1534/genetics.114.173849  1
2015 Zhang P, Elabd S, Hammer S, Solozobova V, Yan H, Bartel F, Inoue S, Henrich T, Wittbrodt J, Loosli F, Davidson G, Blattner C. TRIM25 has a dual function in the p53/Mdm2 circuit. Oncogene. PMID 25728675 DOI: 10.1038/onc.2015.21  1
2015 Heermann S, Schütz L, Lemke S, Krieglstein K, Wittbrodt J. Eye morphogenesis driven by epithelial flow into the optic cup facilitated by modulation of bone morphogenetic protein. Elife. 4. PMID 25719386 DOI: 10.7554/eLife.05216  1
2015 Stemmer M, Schuhmacher LN, Foulkes NS, Bertolucci C, Wittbrodt J. Cavefish eye loss in response to an early block in retinal differentiation progression. Development (Cambridge, England). 142: 743-52. PMID 25617433 DOI: 10.1242/Dev.114629  1
2015 Mateo JL, van den Berg DL, Haeussler M, Drechsel D, Gaber ZB, Castro DS, Robson P, Crawford GE, Flicek P, Ettwiller L, Wittbrodt J, Guillemot F, Martynoga B. Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal. Genome Research. 25: 41-56. PMID 25294244 DOI: 10.1101/Gr.173435.114  1
2014 Chen Q, Su Y, Wesslowski J, Hagemann AI, Ramialison M, Wittbrodt J, Scholpp S, Davidson G. Tyrosine phosphorylation of LRP6 by Src and Fer inhibits Wnt/β-catenin signalling. Embo Reports. 15: 1254-67. PMID 25391905 DOI: 10.15252/embr.201439644  1
2014 Crespo CL, Vernieri C, Keller PJ, Garrè M, Bender JR, Wittbrodt J, Pardi R. The PAR complex controls the spatiotemporal dynamics of F-actin and the MTOC in directionally migrating leukocytes. Journal of Cell Science. 127: 4381-95. PMID 25179599 DOI: 10.1242/Jcs.146217  1
2014 Sinn R, Peravali R, Heermann S, Wittbrodt J. Differential responsiveness of distinct retinal domains to Atoh7. Mechanisms of Development. 133: 218-29. PMID 25151399 DOI: 10.1016/j.mod.2014.08.002  1
2014 Centanin L, Ander JJ, Hoeckendorf B, Lust K, Kellner T, Kraemer I, Urbany C, Hasel E, Harris WA, Simons BD, Wittbrodt J. Exclusive multipotency and preferential asymmetric divisions in post-embryonic neural stem cells of the fish retina. Development (Cambridge, England). 141: 3472-82. PMID 25142461 DOI: 10.1242/Dev.109892  1
2014 Tena JJ, González-Aguilera C, Fernández-Miñán A, Vázquez-Marín J, Parra-Acero H, Cross JW, Rigby PW, Carvajal JJ, Wittbrodt J, Gómez-Skarmeta JL, Martínez-Morales JR. Comparative epigenomics in distantly related teleost species identifies conserved cis-regulatory nodes active during the vertebrate phylotypic period. Genome Research. 24: 1075-85. PMID 24709821 DOI: 10.1101/gr.163915.113  1
2014 Spivakov M, Auer TO, Peravali R, Dunham I, Dolle D, Fujiyama A, Toyoda A, Aizu T, Minakuchi Y, Loosli F, Naruse K, Birney E, Wittbrodt J. Genomic and phenotypic characterization of a wild medaka population: towards the establishment of an isogenic population genetic resource in fish. G3 (Bethesda, Md.). 4: 433-45. PMID 24408034 DOI: 10.1534/G3.113.008722  1
2014 Centanin L, Wittbrodt J. Retinal neurogenesis. Development (Cambridge, England). 141: 241-4. PMID 24381194 DOI: 10.1242/dev.083642  1
2013 Müller C, Maeso I, Wittbrodt J, Martínez-Morales JR. The medaka mutation tintachina sheds light on the evolution of V-ATPase B subunits in vertebrates. Scientific Reports. 3: 3217. PMID 24225653 DOI: 10.1038/srep03217  1
2013 Kirchmaier S, Lust K, Wittbrodt J. Golden GATEway cloning--a combinatorial approach to generate fusion and recombination constructs. Plos One. 8: e76117. PMID 24116091 DOI: 10.1371/journal.pone.0076117  1
2013 Kirchmaier S, Höckendorf B, Möller EK, Bornhorst D, Spitz F, Wittbrodt J. Efficient site-specific transgenesis and enhancer activity tests in medaka using PhiC31 integrase. Development (Cambridge, England). 140: 4287-95. PMID 24048591 DOI: 10.1242/Dev.096081  1
2013 Martynoga B, Mateo JL, Zhou B, Andersen J, Achimastou A, Urbán N, van den Berg D, Georgopoulou D, Hadjur S, Wittbrodt J, Ettwiller L, Piper M, Gronostajski RM, Guillemot F. Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence. Genes & Development. 27: 1769-86. PMID 23964093 DOI: 10.1101/Gad.216804.113  1
2013 Schaafhausen MK, Yang WJ, Centanin L, Wittbrodt J, Bosserhoff A, Fischer A, Schartl M, Meierjohann S. Tumor angiogenesis is caused by single melanoma cells in a manner dependent on reactive oxygen species and NF-κB. Journal of Cell Science. 126: 3862-72. PMID 23843609 DOI: 10.1242/Jcs.125021  1
2013 Bärenz F, Inoue D, Yokoyama H, Tegha-Dunghu J, Freiss S, Draeger S, Mayilo D, Cado I, Merker S, Klinger M, Hoeckendorf B, Pilz S, Hupfeld K, Steinbeisser H, Lorenz H, ... ... Wittbrodt J, et al. The centriolar satellite protein SSX2IP promotes centrosome maturation. The Journal of Cell Biology. 202: 81-95. PMID 23816619 DOI: 10.1083/jcb.201302122  1
2013 Herder C, Swiercz JM, Müller C, Peravali R, Quiring R, Offermanns S, Wittbrodt J, Loosli F. ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation. Development (Cambridge, England). 140: 2787-97. PMID 23698346 DOI: 10.1242/dev.096487  1
2013 Sinn R, Wittbrodt J. An eye on eye development. Mechanisms of Development. 130: 347-58. PMID 23684892 DOI: 10.1016/j.mod.2013.05.001  1
2013 Volbehr U, Wittbrodt J. MoD special issue on molecular and cellular bases of neural development Mechanisms of Development. 130: 323. DOI: 10.1016/j.mod.2013.05.003  1
2012 Höckendorf B, Thumberger T, Wittbrodt J. Quantitative analysis of embryogenesis: a perspective for light sheet microscopy. Developmental Cell. 23: 1111-20. PMID 23237945 DOI: 10.1016/j.devcel.2012.10.008  1
2012 Alten L, Schuster-Gossler K, Eichenlaub MP, Wittbrodt B, Wittbrodt J, Gossler A. A novel mammal-specific three partite enhancer element regulates node and notochord-specific Noto expression. Plos One. 7: e47785. PMID 23110100 DOI: 10.1371/journal.pone.0047785  1
2012 Bogdanović O, Delfino-Machín M, Nicolás-Pérez M, Gavilán MP, Gago-Rodrigues I, Fernández-Miñán A, Lillo C, Ríos RM, Wittbrodt J, Martínez-Morales JR. Numb/Numbl-Opo antagonism controls retinal epithelium morphogenesis by regulating integrin endocytosis. Developmental Cell. 23: 782-95. PMID 23041384 DOI: 10.1016/j.devcel.2012.09.004  1
2012 Schulz S, Chachami G, Kozaczkiewicz L, Winter U, Stankovic-Valentin N, Haas P, Hofmann K, Urlaub H, Ovaa H, Wittbrodt J, Meulmeester E, Melchior F. Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions. Embo Reports. 13: 930-8. PMID 22878415 DOI: 10.1038/embor.2012.125  1
2012 Ramialison M, Reinhardt R, Henrich T, Wittbrodt B, Kellner T, Lowy CM, Wittbrodt J. Cis-regulatory properties of medaka synexpression groups. Development (Cambridge, England). 139: 917-28. PMID 22318626 DOI: 10.1242/dev.071803  1
2012 Fangerau J, Höckendorf B, Wittbrodt J, Leitte H. Similarity analysis of cell movements in video microscopy Ieee Symposium On Biological Data Visualization 2012, Biovis 2012 - Proceedings. 69-76. DOI: 10.1109/BioVis.2012.6378595  1
2011 Centanin L, Hoeckendorf B, Wittbrodt J. Fate restriction and multipotency in retinal stem cells. Cell Stem Cell. 9: 553-62. PMID 22136930 DOI: 10.1016/j.stem.2011.11.004  1
2011 Mongin E, Auer TO, Bourrat F, Gruhl F, Dewar K, Blanchette M, Wittbrodt J, Ettwiller L. Combining computational prediction of cis-regulatory elements with a new enhancer assay to efficiently label neuronal structures in the medaka fish. Plos One. 6: e19747. PMID 21637758 DOI: 10.1371/Journal.Pone.0019747  1
2011 Inoue D, Wittbrodt J. One for all--a highly efficient and versatile method for fluorescent immunostaining in fish embryos. Plos One. 6: e19713. PMID 21603650 DOI: 10.1371/journal.pone.0019713  1
2011 Maurya AK, Tan H, Souren M, Wang X, Wittbrodt J, Ingham PW. Integration of Hedgehog and BMP signalling by the engrailed2a gene in the zebrafish myotome. Development (Cambridge, England). 138: 755-65. PMID 21266411 DOI: 10.1242/dev.062521  1
2010 Keller PJ, Schmidt AD, Santella A, Khairy K, Bao Z, Wittbrodt J, Stelzer EH. Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy. Nature Methods. 7: 637-42. PMID 20601950 DOI: 10.1038/Nmeth.1476  1
2010 Haudry Y, Ramialison M, Paten B, Wittbrodt J, Ettwiller L. Using Trawler_standalone to discover overrepresented motifs in DNA and RNA sequences derived from various experiments including chromatin immunoprecipitation. Nature Protocols. 5: 323-34. PMID 20134431 DOI: 10.1038/Nprot.2009.158  1
2010 Brown KE, Keller PJ, Ramialison M, Rembold M, Stelzer EH, Loosli F, Wittbrodt J. Nlcam modulates midline convergence during anterior neural plate morphogenesis. Developmental Biology. 339: 14-25. PMID 20005219 DOI: 10.1016/J.Ydbio.2009.12.003  0.76
2009 Martinez-Morales JR, Wittbrodt J. Shaping the vertebrate eye. Current Opinion in Genetics & Development. 19: 511-7. PMID 19819125 DOI: 10.1016/j.gde.2009.08.003  1
2009 Bajoghli B, Ramialison M, Aghaallaei N, Czerny T, Wittbrodt J. Identification of starmaker-like in medaka as a putative target gene of Pax2 in the otic vesicle. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 2860-6. PMID 19795520 DOI: 10.1002/dvdy.22093  1
2009 Mertes F, Martinez-Morales JR, Nolden T, Spörle R, Wittbrodt J, Lehrach H, Himmelbauer H. Cloning of mouse ojoplano, a reticular cytoplasmic protein expressed during embryonic development. Gene Expression Patterns : Gep. 9: 562-7. PMID 19766735 DOI: 10.1016/J.Gep.2009.09.003  1
2009 Souren M, Martinez-Morales JR, Makri P, Wittbrodt B, Wittbrodt J. A global survey identifies novel upstream components of the Ath5 neurogenic network. Genome Biology. 10: R92. PMID 19735568 DOI: 10.1186/gb-2009-10-9-r92  1
2009 Martinez-Morales JR, Rembold M, Greger K, Simpson JC, Brown KE, Quiring R, Pepperkok R, Martin-Bermudo MD, Himmelbauer H, Wittbrodt J. ojoplano-mediated basal constriction is essential for optic cup morphogenesis. Development (Cambridge, England). 136: 2165-75. PMID 19502481 DOI: 10.1242/dev.033563  1
2009 Sano S, Takashima S, Niwa H, Yokoi H, Shimada A, Arenz A, Wittbrodt J, Takeda H. Characterization of teleost Mdga1 using a gene-trap approach in medaka (Oryzias latipes). Genesis (New York, N.Y. : 2000). 47: 505-13. PMID 19422017 DOI: 10.1002/Dvg.20528  1
2009 Signore IA, Guerrero N, Loosli F, Colombo A, Villalón A, Wittbrodt J, Concha ML. Zebrafish and medaka: model organisms for a comparative developmental approach of brain asymmetry. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 364: 991-1003. PMID 19064351 DOI: 10.1098/rstb.2008.0260  1
2009 Keller PJ, Schmidt AD, Wittbrodt J, Stelzer EHK. The zebrafish digital embryo: In toto reconstruction of zebrafish early embryonic development with digital scanned laser light sheet fluorescence microscopy Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7367. DOI: 10.1117/12.831496  1
2008 Ettwiller L, Budd A, Spitz F, Wittbrodt J. Analysis of mammalian gene batteries reveals both stable ancestral cores and highly dynamic regulatory sequences. Genome Biology. 9: R172. PMID 19087242 DOI: 10.1186/Gb-2008-9-12-R172  1
2008 Grabher C, Wittbrodt J. Recent advances in meganuclease-and transposon-mediated transgenesis of medaka and zebrafish. Methods in Molecular Biology (Clifton, N.J.). 461: 521-39. PMID 19030821 DOI: 10.1007/978-1-60327-483-8_36  1
2008 Keller PJ, Schmidt AD, Wittbrodt J, Stelzer EH. Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy. Science (New York, N.Y.). 322: 1065-9. PMID 18845710 DOI: 10.1126/Science.1162493  1
2008 Ramialison M, Bajoghli B, Aghaallaei N, Ettwiller L, Gaudan S, Wittbrodt B, Czerny T, Wittbrodt J. Rapid identification of PAX2/5/8 direct downstream targets in the otic vesicle by combinatorial use of bioinformatics tools. Genome Biology. 9: R145. PMID 18828907 DOI: 10.1186/Gb-2008-9-10-R145  1
2008 Haudry Y, Berube H, Letunic I, Weeber PD, Gagneur J, Girardot C, Kapushesky M, Arendt D, Bork P, Brazma A, Furlong EE, Wittbrodt J, Henrich T. 4DXpress: a database for cross-species expression pattern comparisons. Nucleic Acids Research. 36: D847-53. PMID 17916571 DOI: 10.1093/Nar/Gkm797  1
2008 Del Bene F, Wittbrodt J. Eye Development Cell Signaling and Growth Factors in Development: From Molecules to Organogenesis. 2: 440-485. DOI: 10.1002/9783527619689.ch13  1
2008 Haudry Y, Ong CK, Ettwiller L, Berube H, Letunic I, Kapushesky M, Weeber PD, Wang X, Gagneur J, Girardot C, Arendt D, Bork P, Brazma A, Furlong E, Wittbrodt J, et al. Comparing and analysing gene expression patterns across animal species using 4DXpress Series On Advances in Bioinformatics and Computational Biology. 6: 373-382.  1
2007 Grabher C, Wittbrodt J. Meganuclease and transposon mediated transgenesis in medaka. Genome Biology. 8: S10. PMID 18047687 DOI: 10.1186/gb-2007-8-s1-s10  1
2007 Del Bene F, Ettwiller L, Skowronska-Krawczyk D, Baier H, Matter JM, Birney E, Wittbrodt J. In vivo validation of a computationally predicted conserved Ath5 target gene set. Plos Genetics. 3: 1661-71. PMID 17892326 DOI: 10.1371/Journal.Pgen.0030159  1
2007 Ettwiller L, Paten B, Ramialison M, Birney E, Wittbrodt J. Trawler: de novo regulatory motif discovery pipeline for chromatin immunoprecipitation. Nature Methods. 4: 563-5. PMID 17589518 DOI: 10.1038/Nmeth1061  1
2007 Martinez-Morales JR, Henrich T, Ramialison M, Wittbrodt J. New genes in the evolution of the neural crest differentiation program. Genome Biology. 8: R36. PMID 17352807 DOI: 10.1186/gb-2007-8-3-r36  1
2007 Steinmetz PR, Zelada-Gonzáles F, Burgtorf C, Wittbrodt J, Arendt D. Polychaete trunk neuroectoderm converges and extends by mediolateral cell intercalation. Proceedings of the National Academy of Sciences of the United States of America. 104: 2727-32. PMID 17301244 DOI: 10.1073/Pnas.0606589104  1
2007 Yokoi H, Shimada A, Carl M, Takashima S, Kobayashi D, Narita T, Jindo T, Kimura T, Kitagawa T, Kage T, Sawada A, Naruse K, Asakawa S, Shimizu N, Mitani H, ... ... Wittbrodt J, et al. Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships. Developmental Biology. 304: 326-37. PMID 17261279 DOI: 10.1016/J.Ydbio.2006.12.043  1
2007 Grabher C, Cliffe A, Miura K, Hayflick J, Pepperkok R, Rørth P, Wittbrodt J. Birth and life of tissue macrophages and their migration in embryogenesis and inflammation in medaka. Journal of Leukocyte Biology. 81: 263-71. PMID 17046968 DOI: 10.1189/jlb.0806526  1
2006 Rembold M, Lahiri K, Foulkes NS, Wittbrodt J. Transgenesis in fish: efficient selection of transgenic fish by co-injection with a fluorescent reporter construct. Nature Protocols. 1: 1133-9. PMID 17406394 DOI: 10.1038/nprot.2006.165  1
2006 Rembold M, Loosli F, Adams RJ, Wittbrodt J. Individual cell migration serves as the driving force for optic vesicle evagination. Science (New York, N.Y.). 313: 1130-4. PMID 16931763 DOI: 10.1126/science.1127144  1
2006 Swindell EC, Bailey TJ, Loosli F, Liu C, Amaya-Manzanares F, Mahon KA, Wittbrodt J, Jamrich M. Rx-Cre, a tool for inactivation of gene expression in the developing retina. Genesis (New York, N.Y. : 2000). 44: 361-3. PMID 16850473 DOI: 10.1002/dvg.20225  1
2006 Nakamura S, Kobayashi D, Aoki Y, Yokoi H, Ebe Y, Wittbrodt J, Tanaka M. Identification and lineage tracing of two populations of somatic gonadal precursors in medaka embryos. Developmental Biology. 295: 678-88. PMID 16682019 DOI: 10.1016/j.ydbio.2006.03.052  1
2005 Fritzsch B, Piatigorsky J, Tessmar-Raible K, Jékely G, Guy K, Raible F, Wittbrodt J, Arendt D. Ancestry of Photic and Mechanic Sensation? Science (New York, N.Y.). 308: 1113-1114. PMID 15908343 DOI: 10.1126/Science.308.5725.1113  1
2005 Henrich T, Ramialison M, Wittbrodt B, Assouline B, Bourrat F, Berger A, Himmelbauer H, Sasaki T, Shimizu N, Westerfield M, Kondoh H, Wittbrodt J. MEPD: a resource for medaka gene expression patterns. Bioinformatics (Oxford, England). 21: 3195-7. PMID 15879458 DOI: 10.1093/Bioinformatics/Bti478  1
2005 Del Bene F, Wittbrodt J. Cell cycle control by homeobox genes in development and disease. Seminars in Cell & Developmental Biology. 16: 449-60. PMID 15840452 DOI: 10.1016/j.semcdb.2005.02.001  1
2005 Schäfer M, Rembold M, Wittbrodt J, Schartl M, Winkler C. Medial floor plate formation in zebrafish consists of two phases and requires trunk-derived Midkine-a. Genes & Development. 19: 897-902. PMID 15833916 DOI: 10.1101/Gad.336305  1
2005 Martinez-Morales JR, Del Bene F, Nica G, Hammerschmidt M, Bovolenta P, Wittbrodt J. Differentiation of the vertebrate retina is coordinated by an FGF signaling center. Developmental Cell. 8: 565-74. PMID 15809038 DOI: 10.1016/j.devcel.2005.01.022  1
2004 Grabher C, Joly JS, Wittbrodt J. Highly efficient zebrafish transgenesis mediated by the meganuclease I-SceI. Methods in Cell Biology. 77: 381-401. PMID 15602923 DOI: 10.1016/S0091-679X(04)77021-1  1
2004 Schartl M, Nanda I, Kondo M, Schmid M, Asakawa S, Sasaki T, Shimizu N, Henrich T, Wittbrodt J, Furutani-Seiki M, Kondoh H, Himmelbauer H, Hong Y, Koga A, Nonaka M, et al. Current status of medaka genetics and genomics. The Medaka Genome Initiative (MGI). Methods in Cell Biology. 77: 173-99. PMID 15602912 DOI: 10.1016/S0091-679X(04)77010-7  1
2004 Arendt D, Tessmar-Raible K, Snyman H, Dorresteijn AW, Wittbrodt J. Ciliary photoreceptors with a vertebrate-type opsin in an invertebrate brain. Science (New York, N.Y.). 306: 869-71. PMID 15514158 DOI: 10.1515/Nf-2005-0106  1
2004 Grabher C, Wittbrodt J. Efficient activation of gene expression using a heat-shock inducible Gal4/Vp16-UAS system in medaka. Bmc Biotechnology. 4: 26. PMID 15507134 DOI: 10.1186/1472-6750-4-26  1
2004 Huisken J, Swoger J, Del Bene F, Wittbrodt J, Stelzer EH. Optical sectioning deep inside live embryos by selective plane illumination microscopy. Science (New York, N.Y.). 305: 1007-9. PMID 15310904 DOI: 10.1126/science.1100035  1
2004 Quiring R, Wittbrodt B, Henrich T, Ramialison M, Burgtorf C, Lehrach H, Wittbrodt J. Large-scale expression screening by automated whole-mount in situ hybridization. Mechanisms of Development. 121: 971-6. PMID 15210201 DOI: 10.1016/J.Mod.2004.03.031  1
2004 Rembold M, Wittbrodt J. In vivo time-lapse imaging in medaka--n-heptanol blocks contractile rhythmical movements. Mechanisms of Development. 121: 965-70. PMID 15210200 DOI: 10.1016/j.mod.2004.03.016  1
2004 Henrich T, Ramialison M, Segerdell E, Westerfield M, Furutani-Seiki M, Wittbrodt J, Kondoh H. GSD: a genetic screen database. Mechanisms of Development. 121: 959-63. PMID 15210199 DOI: 10.1016/J.Mod.2004.02.006  1
2004 Watanabe T, Asaka S, Kitagawa D, Saito K, Kurashige R, Sasado T, Morinaga C, Suwa H, Niwa K, Henrich T, Hirose Y, Yasuoka A, Yoda H, Deguchi T, Iwanami N, ... ... Wittbrodt J, et al. Mutations affecting liver development and function in Medaka, Oryzias latipes, screened by multiple criteria. Mechanisms of Development. 121: 791-802. PMID 15210186 DOI: 10.1016/j.mod.2004.04.004  1
2004 Yoda H, Hirose Y, Yasuoka A, Sasado T, Morinaga C, Deguchi T, Henrich T, Iwanami N, Watanabe T, Osakada M, Kunimatsu S, Wittbrodt J, Suwa H, Niwa K, Okamoto Y, et al. Mutations affecting retinotectal axonal pathfinding in Medaka, Oryzias latipes. Mechanisms of Development. 121: 715-28. PMID 15210179 DOI: 10.1016/j.mod.2004.03.021  1
2004 Loosli F, Del Bene F, Quiring R, Rembold M, Martinez-Morales JR, Carl M, Grabher C, Iquel C, Krone A, Wittbrodt B, Winkler S, Sasado T, Morinaga C, Suwa H, Niwa K, ... ... Wittbrodt J, et al. Mutations affecting retina development in Medaka. Mechanisms of Development. 121: 703-14. PMID 15210178 DOI: 10.1016/J.Mod.2004.03.004  1
2004 Kitagawa D, Watanabe T, Saito K, Asaka S, Sasado T, Morinaga C, Suwa H, Niwa K, Yasuoka A, Deguchi T, Yoda H, Hirose Y, Henrich T, Iwanami N, Kunimatsu S, ... ... Wittbrodt J, et al. Genetic dissection of the formation of the forebrain in Medaka, Oryzias latipes. Mechanisms of Development. 121: 673-85. PMID 15210176 DOI: 10.1016/j.mod.2004.03.010  1
2004 Elmasri H, Winkler C, Liedtke D, Sasado T, Morinaga C, Suwa H, Niwa K, Henrich T, Hirose Y, Yasuoka A, Yoda H, Watanabe T, Deguchi T, Iwanami N, Kunimatsu S, ... ... Wittbrodt J, et al. Mutations affecting somite formation in the Medaka (Oryzias latipes). Mechanisms of Development. 121: 659-71. PMID 15210175 DOI: 10.1016/j.mod.2004.04.003  1
2004 Furutani-Seiki M, Sasado T, Morinaga C, Suwa H, Niwa K, Yoda H, Deguchi T, Hirose Y, Yasuoka A, Henrich T, Watanabe T, Iwanami N, Kitagawa D, Saito K, Asaka S, ... ... Wittbrodt J, et al. A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes. Mechanisms of Development. 121: 647-58. PMID 15210174 DOI: 10.1016/j.mod.2004.04.016  1
2004 Furutani-Seiki M, Wittbrodt J. Medaka and zebrafish, an evolutionary twin study. Mechanisms of Development. 121: 629-37. PMID 15210172 DOI: 10.1016/j.mod.2004.05.010  1
2004 Poggi L, Vottari T, Barsacchi G, Wittbrodt J, Vignali R. The homeobox gene Xbh1 cooperates with proneural genes to specify ganglion cell fate within the Xenopus neural retina. Development (Cambridge, England). 131: 2305-15. PMID 15102701 DOI: 10.1242/Dev.01099  1
2004 Martinez-Morales JR, Naruse K, Mitani H, Shima A, Wittbrodt J. Rapid chromosomal assignment of medaka mutants by bulked segregant analysis. Gene. 329: 159-65. PMID 15033538 DOI: 10.1016/j.gene.2003.12.028  1
2004 Del Bene F, Tessmar-Raible K, Wittbrodt J. Direct interaction of geminin and Six3 in eye development. Nature. 427: 745-9. PMID 14973488 DOI: 10.1038/Nature02292  1
2003 Grabher C, Henrich T, Sasado T, Arenz A, Wittbrodt J, Furutani-Seiki M. Transposon-mediated enhancer trapping in medaka. Gene. 322: 57-66. PMID 14644497 DOI: 10.1016/J.Gene.2003.09.009  1
2003 Prud'homme B, de Rosa R, Arendt D, Julien JF, Pajaziti R, Dorresteijn AW, Adoutte A, Wittbrodt J, Balavoine G. Arthropod-like expression patterns of engrailed and wingless in the annelid Platynereis dumerilii suggest a role in segment formation. Current Biology : Cb. 13: 1876-81. PMID 14588243 DOI: 10.1016/J.Cub.2003.10.006  1
2003 Loosli F, Staub W, Finger-Baier KC, Ober EA, Verkade H, Wittbrodt J, Baier H. Loss of eyes in zebrafish caused by mutation of chokh/rx3. Embo Reports. 4: 894-9. PMID 12947416 DOI: 10.1038/sj.embor.embor919  1
2003 Hammerschmidt M, Kramer C, Nowak M, Herzog W, Wittbrodt J. Loss of maternal Smad5 in zebrafish embryos affects patterning and morphogenesis of optic primordia. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 227: 128-33. PMID 12701105 DOI: 10.1002/dvdy.10281  1
2003 Shima A, Himmelbauer H, Mitani H, Furutani-Seiki M, Wittbrodt J, Schartl M. Fish genomes flying. Symposium on Medaka Genomics. Embo Reports. 4: 121-5. PMID 12612598 DOI: 10.1038/Sj.Embor.Embor743  1
2003 Henrich T, Ramialison M, Quiring R, Wittbrodt B, Furutani-Seiki M, Wittbrodt J, Kondoh H. MEPD: a Medaka gene expression pattern database. Nucleic Acids Research. 31: 72-4. PMID 12519950 DOI: 10.1093/nar/gkg017  1
2003 López-Ríos J, Tessmar K, Loosli F, Wittbrodt J, Bovolenta P. Six3 and Six6 activity is modulated by members of the groucho family. Development (Cambridge, England). 130: 185-95. PMID 12441302 DOI: 10.1242/dev.00185  1
2002 Tessmar K, Loosli F, Wittbrodt J. A screen for co-factors of Six3. Mechanisms of Development. 117: 103-13. PMID 12204251 DOI: 10.1016/S0925-4773(02)00185-5  1
2002 Poggi L, Carl M, Vignali R, Barsacchi G, Wittbrodt J. Expression of a medaka (Oryzias latipes) Bar homologue in the differentiating central nervous system and retina. Mechanisms of Development. 114: 193-6. PMID 12175510 DOI: 10.1016/S0925-4773(02)00054-0  1
2002 Carl M, Loosli F, Wittbrodt J. Six3 inactivation reveals its essential role for the formation and patterning of the vertebrate eye. Development (Cambridge, England). 129: 4057-63. PMID 12163408  1
2002 Arendt D, Tessmar K, de Campos-Baptista MI, Dorresteijn A, Wittbrodt J. Development of pigment-cup eyes in the polychaete Platynereis dumerilii and evolutionary conservation of larval eyes in Bilateria. Development (Cambridge, England). 129: 1143-54. PMID 11874910  1
2002 Loosli F, Mardon G, Wittbrodt J. Cloning and expression of medaka Dachshund. Mechanisms of Development. 112: 203-6. PMID 11850196 DOI: 10.1016/S0925-4773(01)00649-9  1
2002 Wittbrodt J, Shima A, Schartl M. Medaka--a model organism from the far East. Nature Reviews. Genetics. 3: 53-64. PMID 11823791 DOI: 10.1038/Nrg704  1
2001 Loosli F, Winkler S, Burgtorf C, Wurmbach E, Ansorge W, Henrich T, Grabher C, Arendt D, Carl M, Krone A, Grzebisz E, Wittbrodt J. Medaka eyeless is the key factor linking retinal determination and eye growth. Development (Cambridge, England). 128: 4035-44. PMID 11641226  1
2001 Arendt D, Wittbrodt J. Reconstructing the eyes of Urbilateria. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 1545-63. PMID 11604122 DOI: 10.1098/Rstb.2001.0971  1
2001 Adamska M, Wolff A, Kreusler M, Wittbrodt J, Braun T, Bober E. Five Nkx5 genes show differential expression patterns in anlagen of sensory organs in medaka: insight into the evolution of the gene family. Development Genes and Evolution. 211: 338-49. PMID 11466530 DOI: 10.1007/s004270100162  1
2001 Arendt D, Technau U, Wittbrodt J. Evolution of the bilaterian larval foregut. Nature. 409: 81-5. PMID 11343117 DOI: 10.1038/35051075  1
2000 Loosli F, Köster RW, Carl M, Kühnlein R, Henrich T, Mücke M, Krone A, Wittbrodt J. A genetic screen for mutations affecting embryonic development in medaka fish (Oryzias latipes). Mechanisms of Development. 97: 133-9. PMID 11025214 DOI: 10.1016/S0925-4773(00)00406-8  1
2000 Köster RW, Kühnlein RP, Wittbrodt J. Ectopic Sox3 activity elicits sensory placode formation. Mechanisms of Development. 95: 175-87. PMID 10906460 DOI: 10.1016/S0925-4773(00)00356-7  1
2000 Winkler S, Loosli F, Henrich T, Wakamatsu Y, Wittbrodt J. The conditional medaka mutation eyeless uncouples patterning and morphogenesis of the eye. Development (Cambridge, England). 127: 1911-9. PMID 10751179  1
1999 Carl M, Wittbrodt J. Graded interference with FGF signalling reveals its dorsoventral asymmetry at the mid-hindbrain boundary. Development (Cambridge, England). 126: 5659-67. PMID 10572042  1
1999 Schartl M, Hornung U, Gutbrod H, Volff JN, Wittbrodt J. Melanoma loss-of-function mutants in Xiphophorus caused by Xmrk-oncogene deletion and gene disruption by a transposable element. Genetics. 153: 1385-94. PMID 10545466  1
1999 Ristoratore F, Carl M, Deschet K, Richard-Parpaillon L, Boujard D, Wittbrodt J, Chourrout D, Bourrat F, Joly JS. The midbrain-hindbrain boundary genetic cascade is activated ectopically in the diencephalon in response to the widespread expression of one of its components, the medaka gene Ol-eng2. Development (Cambridge, England). 126: 3769-79. PMID 10433907  1
1999 Loosli F, Winkler S, Wittbrodt J. Six3 overexpression initiates the formation of ectopic retina. Genes & Development. 13: 649-54. PMID 10090721 DOI: 10.1101/Gad.13.6.649  1
1999 Engel W, Wittbrodt J. The 2nd Symposium of the SFB 271 'Molecular genetic morphoregulatory processes' on the topic 'Morphoregulation', 10-11 October 1998 in Gottingen | 2. Symposium des SFB 271 'Molekulare genetic morphoregulatorischer prozesses' zum Thema 'morphoregulation' Gottingen, 10.-11.10.1998 Medizinische Genetik. 11: 341-342.  1
1998 Loosli F, Köster RW, Carl M, Krone A, Wittbrodt J. Six3, a medaka homologue of the Drosophila homeobox gene sine oculis is expressed in the anterior embryonic shield and the developing eye. Mechanisms of Development. 74: 159-64. PMID 9651515 DOI: 10.1016/S0925-4773(98)00055-0  1
1998 Wittbrodt J, Meyer A, Schartl M. More genes in fish? Bioessays. 20: 511-515. DOI: 10.1002/(Sici)1521-1878(199806)20:6<511::Aid-Bies10>3.0.Co;2-3  1
1997 Koster R, Stick R, Loosli F, Wittbrodt J. Medaka spalt acts as a target gene of hedgehog signaling. Development (Cambridge, England). 124: 3147-56. PMID 9272955  1
1997 Gruss P, Stoykova A, Grtz M, Price J, Tones M, Loosli F, Wittbrodt J, Oliver G. Pax and six genes in vertebrate eye development Faseb Journal. 11: A1015.  1
1996 Oliver G, Loosli F, Köster R, Wittbrodt J, Gruss P. Ectopic lens induction in fish in response to the murine homeobox gene Six3. Mechanisms of Development. 60: 233-9. PMID 9025075 DOI: 10.1016/S0925-4773(96)00632-6  1
1994 Winkler C, Wittbrodt J, Lammers R, Ullrich A, Schartl M. Ligand-dependent tumor induction in medakafish embryos by a Xmrk receptor tyrosine kinase transgene. Oncogene. 9: 1517-25. PMID 8183545  1
1994 Malitschek B, Wittbrodt J, Fischer P, Lammers R, Ullrich A, Schartl M. Autocrine stimulation of the Xmrk receptor tyrosine kinase in Xiphophorus melanoma cells and identification of a source for the physiological ligand. The Journal of Biological Chemistry. 269: 10423-30. PMID 8144625  1
1994 Wittbrodt J, Rosa FM. Disruption of mesoderm and axis formation in fish by ectopic expression of activin variants: the role of maternal activin. Genes & Development. 8: 1448-62. PMID 7926744 DOI: 10.1101/Gad.8.12.1448  1
1992 Winkler C, Hong Y, Wittbrodt J, Schartl M. Analysis of heterologous and homologous promoters and enhancers in vitro and in vivo by gene transfer into Japanese medaka (Oryzias latipes) Xiphophorus. Molecular Marine Biology and Biotechnology. 1: 326-37. PMID 1339229  1
1992 Wittbrodt J, Lammers R, Malitschek B, Ullrich A, Schartl M. The Xmrk receptor tyrosine kinase is activated in Xiphophorus malignant melanoma. The Embo Journal. 11: 4239-46. PMID 1327761 DOI: 10.1002/J.1460-2075.1992.Tb05518.X  1
1991 Wiesmüller L, Wittbrodt J, Noegel AA, Schleicher M. Purification and cDNA-derived sequence of adenylosuccinate synthetase from Dictyostelium discoideum. The Journal of Biological Chemistry. 266: 2480-5. PMID 1989999  1
1991 Förnzler D, Wittbrodt J, Schartl M. Analysis of an esterase linked to a locus involved in the regulation of the melanoma oncogene and isolation of polymorphic marker sequences in Xiphophorus. Biochemical Genetics. 29: 509-24. PMID 1687910 DOI: 10.1007/Bf02426867  1
1989 Wittbrodt J, Adam D, Malitschek B, Mäueler W, Raulf F, Telling A, Robertson SM, Schartl M. Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus. Nature. 341: 415-21. PMID 2797166 DOI: 10.1038/341415A0  1
1989 Wittbrodt J, Erhardt W. An inexpensive and versatile computer-controlled PCR machine using a Peltier Element as a thermoelectric heat pump. Trends in Genetics : Tig. 5: 202-3. PMID 2781606 DOI: 10.1016/0168-9525(89)90081-4  1
1988 Adam D, Wittbrodt J, Telling A, Schartl M. RFLP for an EGF-receptor related gene associated with the melanoma oncogene locus of Xiphophorus maculatus. Nucleic Acids Research. 16: 7212. PMID 2900499 DOI: 10.1093/Nar/16.14.7212  1
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