| Year |
Citation |
Score |
| 2024 |
Martínez-González B, Soria ME, Mínguez P, Lorenzo-Redondo R, Salar-Vidal L, López-García A, Esteban-Muñoz M, Durán-Pastor A, Somovilla P, García-Crespo C, de Ávila AI, Gómez J, Esteban J, Fernández-Roblas R, Gadea I, ... Domingo E, et al. SARS-CoV-2 mutant spectra as variant of concern nurseries: endless variation? Frontiers in Microbiology. 15: 1358258. PMID 38559344 DOI: 10.3389/fmicb.2024.1358258 |
0.358 |
|
| 2024 |
Delgado S, Somovilla P, Ferrer-Orta C, Martínez-González B, Vázquez-Monteagudo S, Muñoz-Flores J, Soria ME, García-Crespo C, de Ávila AI, Durán-Pastor A, Gadea I, López-Galíndez C, Moran F, Lorenzo-Redondo R, Verdaguer N, ... ... Domingo E, et al. Incipient functional SARS-CoV-2 diversification identified through neural network haplotype maps. Proceedings of the National Academy of Sciences of the United States of America. 121: e2317851121. PMID 38416684 DOI: 10.1073/pnas.2317851121 |
0.365 |
|
| 2023 |
Domingo E, Martínez-González B, García-Crespo C, Somovilla P, de Ávila AI, Soria ME, Durán-Pastor A, Perales C. Puzzles, challenges, and information reservoir of SARS-CoV-2 quasispecies. Journal of Virology. 97: e0151123. PMID 38092661 DOI: 10.1128/jvi.01511-23 |
0.372 |
|
| 2023 |
Ariza-Mateos A, Briones C, Perales C, Bayo-Jiménez MT, Domingo E, Gómez J. Viruses as archaeological tools for uncovering ancient molecular relationships. Annals of the New York Academy of Sciences. PMID 37801367 DOI: 10.1111/nyas.15071 |
0.36 |
|
| 2023 |
Martínez-González B, Gallego I, Gregori J, Soria ME, Somovilla P, de Ávila AI, García-Crespo C, Durán-Pastor A, Briones C, Gómez J, Quer J, Domingo E, Perales C. Fitness-Dependent, Mild Mutagenic Activity of Sofosbuvir for Hepatitis C Virus. Antimicrobial Agents and Chemotherapy. 67: e0039423. PMID 37367486 DOI: 10.1128/aac.00394-23 |
0.303 |
|
| 2023 |
Somovilla P, García-Crespo C, Martínez-González B, Soria ME, de Ávila AI, Gallego I, Mínguez P, Durán-Pastor A, Ferrer-Orta C, Salar-Vidal L, Esteban-Muñoz M, Zuñiga S, Sola I, Enjuanes L, Esteban J, ... ... Domingo E, et al. Atypical Mutational Spectrum of SARS-CoV-2 Replicating in the Presence of Ribavirin. Antimicrobial Agents and Chemotherapy. 67: e0131522. PMID 36602354 DOI: 10.1128/aac.01315-22 |
0.559 |
|
| 2023 |
Domingo E, García-Crespo C, Soria ME, Perales C. Viral Fitness, Population Complexity, Host Interactions, and Resistance to Antiviral Agents. Current Topics in Microbiology and Immunology. 439: 197-235. PMID 36592247 DOI: 10.1007/978-3-031-15640-3_6 |
0.404 |
|
| 2022 |
Gregori J, Colomer-Castell S, Campos C, Ibañez-Lligoña M, Garcia-Cehic D, Rando-Segura A, Adombie CM, Pintó R, Guix S, Bosch A, Domingo E, Gallego I, Perales C, Cortese MF, Tabernero D, et al. Quasispecies Fitness Partition to Characterize the Molecular Status of a Viral Population. Negative Effect of Early Ribavirin Discontinuation in a Chronically Infected HEV Patient. International Journal of Molecular Sciences. 23. PMID 36498981 DOI: 10.3390/ijms232314654 |
0.353 |
|
| 2022 |
Ariza-Mateos A, Perales C, Domingo E, Gómez J. Application of archaeological concepts to the interpretation of RNA virus quasi species evolution. Theoretical Biology Forum. 115: 133-143. PMID 36325936 DOI: 10.19272/202211402009 |
0.443 |
|
| 2022 |
Martínez-González B, Soria ME, Vázquez-Sirvent L, Ferrer-Orta C, Lobo-Vega R, Mínguez P, de la Fuente L, Llorens C, Soriano B, Ramos-Ruíz R, Cortón M, López-Rodríguez R, García-Crespo C, Somovilla P, Durán-Pastor A, ... ... Domingo E, et al. SARS-CoV-2 Mutant Spectra at Different Depth Levels Reveal an Overwhelming Abundance of Low Frequency Mutations. Pathogens (Basel, Switzerland). 11. PMID 35745516 DOI: 10.3390/pathogens11060662 |
0.568 |
|
| 2022 |
Martínez-González B, Soria ME, Vázquez-Sirvent L, Ferrer-Orta C, Lobo-Vega R, Mínguez P, de la Fuente L, Llorens C, Soriano B, Ramos R, Cortón M, López-Rodríguez R, García-Crespo C, Gallego I, de Ávila AI, ... ... Domingo E, et al. SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes. Microbiology Spectrum. 10: e0022122. PMID 35348367 DOI: 10.1128/spectrum.00221-22 |
0.561 |
|
| 2022 |
Martínez-González B, Vázquez-Sirvent L, Soria ME, Mínguez P, Salar-Vidal L, García-Crespo C, Gallego I, Ávila A, Llorens C, Soriano B, Ramos-Ruiz R, Esteban J, Fernandez-Roblas R, Gadea I, Ayuso C, ... ... Domingo E, et al. Vaccine-breakthrough infections with SARS-CoV-2 Alpha mirror mutations in Delta Plus, Iota and Omicron. The Journal of Clinical Investigation. PMID 35259127 DOI: 10.1172/JCI157700 |
0.397 |
|
| 2022 |
Torres-Vázquez B, de Lucas AM, García-Crespo C, García-Martín JA, Fragoso A, Fernández-Algar M, Perales C, Domingo E, Moreno M, Briones C. In vitro Selection of High Affinity DNA and RNA Aptamers that Detect Hepatitis C Virus Core Protein of Genotypes 1 to 4 and Inhibit Virus Production in Cell Culture. Journal of Molecular Biology. 434: 167501. PMID 35183559 DOI: 10.1016/j.jmb.2022.167501 |
0.341 |
|
| 2022 |
Sabariegos R, Ortega-Prieto AM, Díaz-Martínez L, Grande-Pérez A, García Crespo C, Gallego I, de Ávila AI, Albentosa-González L, Soria ME, Gastaminza P, Domingo E, Perales C, Mas A. Guanosine inhibits hepatitis C virus replication and increases indel frequencies, associated with altered intracellular nucleotide pools. Plos Pathogens. 18: e1010210. PMID 35085375 DOI: 10.1371/journal.ppat.1010210 |
0.391 |
|
| 2021 |
Caridi F, Cañas-Arranz R, Vázquez-Calvo Á, de León P, Calderón KI, Domingo E, Sobrino F, Martín-Acebes MA. Adaptive value of foot-and-mouth disease virus capsid substitutions with opposite effects on particle acid stability. Scientific Reports. 11: 23494. PMID 34873184 DOI: 10.1038/s41598-021-02757-3 |
0.375 |
|
| 2021 |
Delgado S, Perales C, García-Crespo C, Soria ME, Gallego I, de Ávila AI, Martínez-González B, Vázquez-Sirvent L, López-Galíndez C, Morán F, Domingo E. A Two-Level, Intramutant Spectrum Haplotype Profile of Hepatitis C Virus Revealed by Self-Organized Maps. Microbiology Spectrum. e0145921. PMID 34756074 DOI: 10.1128/Spectrum.01459-21 |
0.437 |
|
| 2021 |
Sabariegos R, Albentosa-González L, Palmero B, Clemente-Casares P, Ramírez E, García-Crespo C, Gallego I, de Ávila AI, Perales C, Domingo E, Mas A. Akt Phosphorylation of Hepatitis C Virus NS5B Regulates Polymerase Activity and Hepatitis C Virus Infection. Frontiers in Microbiology. 12: 754664. PMID 34745059 DOI: 10.3389/fmicb.2021.754664 |
0.417 |
|
| 2021 |
Domingo E, García-Crespo C, Perales C. Historical Perspective on the Discovery of the Quasispecies Concept. Annual Review of Virology. 8: 51-72. PMID 34586874 DOI: 10.1146/annurev-virology-091919-105900 |
0.436 |
|
| 2021 |
Domingo E, García-Crespo C, Lobo-Vega R, Perales C. Mutation Rates, Mutation Frequencies, and Proofreading-Repair Activities in RNA Virus Genetics. Viruses. 13. PMID 34578463 DOI: 10.3390/v13091882 |
0.428 |
|
| 2021 |
García-Crespo C, Gallego I, Soria ME, de Ávila AI, Martínez-González B, Vázquez-Sirvent L, Lobo-Vega R, Moreno E, Gómez J, Briones C, Gregori J, Quer J, Domingo E, Perales C. Population Disequilibrium as Promoter of Adaptive Explorations in Hepatitis C Virus. Viruses. 13. PMID 33916702 DOI: 10.3390/v13040616 |
0.481 |
|
| 2021 |
Domingo E. Quasispecies Theory in Virology. Journal of Virology. 76: 463-465. PMID 33739796 DOI: 10.1128/JVI.76.1.463-465.2002 |
0.344 |
|
| 2020 |
García-Crespo C, Soria ME, Gallego I, Ávila AI, Martínez-González B, Vázquez-Sirvent L, Gómez J, Briones C, Gregori J, Quer J, Perales C, Domingo E. Dissimilar Conservation Pattern in Hepatitis C Virus Mutant Spectra, Consensus Sequences, and Data Banks. Journal of Clinical Medicine. 9. PMID 33121037 DOI: 10.3390/jcm9113450 |
0.467 |
|
| 2020 |
Soria ME, García-Crespo C, Martínez-Gónzalez B, Vázquez-Sirvent L, Lobo-Vega R, de Ávila AI, Gallego I, Chen Q, García-Cehic D, Llorens-Revull M, Briones C, Gómez J, Ferrer-Orta C, Verdaguer N, Gregori J, ... ... Domingo E, et al. Amino acid substitutions associated with treatment failure of hepatitis C virus infection. Journal of Clinical Microbiology. PMID 32999010 DOI: 10.1128/JCM.01985-20 |
0.335 |
|
| 2020 |
Domingo E, Soria ME, Gallego I, de Ávila AI, García-Crespo C, Martínez-González B, Gómez J, Briones C, Gregori J, Quer J, Perales C. A new implication of quasispecies dynamics: Broad virus diversification in absence of external perturbations. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 104278. PMID 32165244 DOI: 10.1016/J.Meegid.2020.104278 |
0.442 |
|
| 2019 |
Gallego I, Soria ME, García-Crespo C, Chen Q, Martínez-Barragán P, Khalfaoui S, Martínez-González B, Sanchez-Martin I, Palacios-Blanco I, de Ávila AI, García-Cehic D, Esteban JI, Gómez J, Briones C, Gregori J, ... ... Domingo E, et al. Broad and dynamic diversification of infectious hepatitis C virus in a cell culture environment. Journal of Virology. PMID 31852791 DOI: 10.1128/Jvi.01856-19 |
0.519 |
|
| 2019 |
Domingo E, Perales C. Viral quasispecies. Plos Genetics. 15: e1008271. PMID 31622336 DOI: 10.1371/journal.pgen.1008271 |
0.52 |
|
| 2019 |
Gallego I, Soria ME, Gregori J, de Ávila AI, García-Crespo C, Moreno E, Gadea I, Esteban J, Fernández-Roblas R, Esteban JI, Gómez J, Quer J, Domingo E, Perales C. Synergistic lethal mutagenesis of hepatitis C virus. Antimicrobial Agents and Chemotherapy. PMID 31570400 DOI: 10.1128/Aac.01653-19 |
0.437 |
|
| 2019 |
Borrego B, de Ávila AI, Domingo E, Brun A. Lethal Mutagenesis of Rift Valley Fever Virus Induced by Favipiravir. Antimicrobial Agents and Chemotherapy. 63. PMID 31085519 DOI: 10.1128/AAC.00669-19 |
0.345 |
|
| 2019 |
Domingo E, Ávila AId, Gallego I, Sheldon J, Perales C. Viral fitness: history and relevance for viral pathogenesis and antiviral interventions. Pathogens and Disease. 77. PMID 30980658 DOI: 10.1093/Femspd/Ftz021 |
0.423 |
|
| 2019 |
Altan-Bonnet N, Perales C, Domingo E. Extracellular vesicles: Vehicles of en bloc viral transmission Virus Research. 265: 143-149. PMID 30928427 DOI: 10.1016/J.Virusres.2019.03.023 |
0.362 |
|
| 2018 |
Gregori J, Soria ME, Gallego I, Guerrero-Murillo M, Esteban JI, Quer J, Perales C, Domingo E. Rare haplotype load as marker for lethal mutagenesis. Plos One. 13. PMID 30281674 DOI: 10.1371/Journal.Pone.0204877 |
0.534 |
|
| 2018 |
Gallego I, Gregori J, Soria ME, García-Crespo C, García-Álvarez M, Gómez-González A, Valiergue R, Gómez J, Esteban JI, Quer J, Domingo E, Perales C. Resistance of high fitness hepatitis C virus to lethal mutagenesis. Virology. 523: 100-109. PMID 30107298 DOI: 10.1016/J.Virol.2018.07.030 |
0.457 |
|
| 2018 |
de la Higuera I, Ferrer-Orta C, Moreno E, de Ávila AI, Soria ME, Singh K, Caridi F, Sobrino F, Sarafianos SG, Perales C, Verdaguer N, Domingo E. Contribution of a multifunctional polymerase region of foot-and-mouth disease virus to lethal mutagenesis. Journal of Virology. PMID 30068642 DOI: 10.1128/Jvi.01119-18 |
0.461 |
|
| 2018 |
Domingo E, Perales C. Quasispecies and virus. European Biophysics Journal : Ebj. PMID 29397419 DOI: 10.1007/S00249-018-1282-6 |
0.471 |
|
| 2017 |
Escribano-Romero E, Jiménez de Oya N, Domingo E, Saiz JC. Extinction of West Nile Virus by Favipiravir through Lethal Mutagenesis. Antimicrobial Agents and Chemotherapy. 61. PMID 28848019 DOI: 10.1128/AAC.01400-17 |
0.392 |
|
| 2017 |
de la Higuera I, Ferrer-Orta C, de Ávila AI, Perales C, Sierra M, Singh K, Sarafianos SG, Dehouck Y, Bastolla U, Verdaguer N, Domingo E. Molecular and functional bases of selection against a mutation bias in an RNA virus. Genome Biology and Evolution. PMID 28460010 DOI: 10.1093/Gbe/Evx075 |
0.539 |
|
| 2017 |
de Avila AI, Moreno E, Perales C, Domingo E. Favipiravir can evoke lethal mutagenesis and extinction of foot-and-mouth disease virus. Virus Research. PMID 28322918 DOI: 10.1016/J.Virusres.2017.03.014 |
0.428 |
|
| 2017 |
Moreno E, Gallego I, Gregori J, Lucía-Sanz A, Soria ME, Castro V, Beach NM, Manrubia SC, Quer J, Esteban JI, Rice CM, Gómez J, Gastaminza P, Domingo E, Perales C. Internal disequilibria and phenotypic diversification during replication of hepatitis C virus in a non-coevolving cellular environment. Journal of Virology. PMID 28275194 DOI: 10.1128/Jvi.02505-16 |
0.435 |
|
| 2017 |
Quer J, Rodríguez-Frias F, Gregori J, Tabernero D, Soria ME, García-Cehic D, Homs M, Bosch A, Pintó RM, Esteban JI, Domingo E, Perales C. Deep sequencing in the management of hepatitis virus infections Virus Research. 239: 115-125. PMID 28040474 DOI: 10.1016/J.Virusres.2016.12.020 |
0.401 |
|
| 2016 |
de Ávila AI, Gallego I, Soria ME, Gregori J, Quer J, Esteban JI, Rice CM, Domingo E, Perales C. Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir. Plos One. 11: e0164691. PMID 27755573 DOI: 10.1371/Journal.Pone.0164691 |
0.343 |
|
| 2016 |
Agudo R, de la Higuera I, Arias A, Grande-Pérez A, Domingo E. Involvement of a joker mutation in a polymerase-independent lethal mutagenesis escape mechanism. Virology. 494: 257-66. PMID 27136067 DOI: 10.1016/j.virol.2016.04.023 |
0.385 |
|
| 2016 |
Gallego I, Sheldon J, Moreno E, Gregori J, Quer J, Esteban JI, Rice CM, Domingo E, Perales C. Barrier-Independent, Fitness-Associated Differences in Sofosbuvir Efficacy against Hepatitis C Virus. Antimicrobial Agents and Chemotherapy. 60: 3786-93. PMID 27067341 DOI: 10.1128/Aac.00581-16 |
0.365 |
|
| 2016 |
Gregori J, Perales C, Rodriguez-Frias F, Esteban JI, Quer J, Domingo E. Viral quasispecies complexity measures Virology. 493: 227-237. PMID 27060566 DOI: 10.1016/J.Virol.2016.03.017 |
0.389 |
|
| 2015 |
Perales C, Quer J, Gregori JM, Esteban JI, Domingo E. Resistance of Hepatitis C Virus to Inhibitors: Complexity and Clinical Implications. Viruses. 7: 5746-5766. PMID 26561827 DOI: 10.3390/V7112902 |
0.317 |
|
| 2015 |
Perales C, Domingo E. Antiviral Strategies Based on Lethal Mutagenesis and Error Threshold. Current Topics in Microbiology and Immunology. 392: 323-339. PMID 26294225 DOI: 10.1007/82_2015_459 |
0.369 |
|
| 2015 |
Perales C, Moreno E, Domingo E. Clonality and intracellular polyploidy in virus evolution and pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: 8887-92. PMID 26195777 DOI: 10.1073/Pnas.1501715112 |
0.421 |
|
| 2015 |
Ferrer-Orta C, de la Higuera I, Caridi F, Sánchez-Aparicio MT, Moreno E, Perales C, Singh K, Sarafianos SG, Sobrino F, Domingo E, Verdaguer N. Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. Journal of Virology. 89: 6848-59. PMID 25903341 DOI: 10.1128/Jvi.03283-14 |
0.303 |
|
| 2015 |
Andino R, Domingo E. Viral quasispecies. Virology. 479: 46-51. PMID 25824477 DOI: 10.1016/j.virol.2015.03.022 |
0.499 |
|
| 2014 |
Sheldon J, Beach NM, Moreno E, Gallego I, Piñeiro D, Martínez-Salas E, Gregori J, Quer J, Esteban JI, Rice CM, Domingo E, Perales C. Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus. Journal of Virology. 88: 12098-111. PMID 25122776 DOI: 10.1128/Jvi.01860-14 |
0.379 |
|
| 2014 |
Perales C, Beach NM, Sheldon J, Domingo E. Molecular basis of interferon resistance in hepatitis C virus. Current Opinion in Virology. 8: 38-44. PMID 24968186 DOI: 10.1016/J.Coviro.2014.05.003 |
0.363 |
|
| 2014 |
Moreno E, Ojosnegros S, García-Arriaza J, Escarmís C, Domingo E, Perales C. Exploration of sequence space as the basis of viral RNA genome segmentation. Proceedings of the National Academy of Sciences of the United States of America. 111: 6678-83. PMID 24757055 DOI: 10.1073/Pnas.1323136111 |
0.363 |
|
| 2013 |
Gregori J, Esteban JI, Cubero M, Garcia-Cehic D, Perales C, Casillas R, Alvarez-Tejado M, Rodríguez-Frías F, Guardia J, Domingo E, Quer J. Ultra-deep pyrosequencing (UDPS) data treatment to study amplicon HCV minor variants Plos One. 8. PMID 24391758 DOI: 10.1371/Journal.Pone.0083361 |
0.405 |
|
| 2013 |
Ortega-Prieto AM, Sheldon J, Grande-Pérez A, Tejero H, Gregori J, Quer J, Esteban JI, Domingo E, Perales C. Extinction of Hepatitis C Virus by Ribavirin in Hepatoma Cells Involves Lethal Mutagenesis Plos One. 8. PMID 23976977 DOI: 10.1371/Journal.Pone.0071039 |
0.379 |
|
| 2013 |
Ramezani F, Norouzi M, Sarizade GR, Poortahmasebi V, Kalantar E, Magnius L, Norder H, Domingo E, Jazayeri SM. Mutation hot spots in hepatitis B surface antigen in chronic carriers from Khoozestan province, southern of Iran. Iranian Journal of Allergy, Asthma, and Immunology. 12: 269-75. PMID 23893811 |
0.382 |
|
| 2013 |
Perales C, Beach NM, Gallego I, Soria ME, Quer J, Esteban JI, Rice C, Domingo E, Sheldon J. Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype. Journal of Virology. 87: 7593-607. PMID 23637397 DOI: 10.1128/Jvi.02824-12 |
0.304 |
|
| 2013 |
Arias A, Isabel de Ávila A, Sanz-Ramos M, Agudo R, Escarmís C, Domingo E. Molecular dissection of a viral quasispecies under mutagenic treatment: positive correlation between fitness loss and mutational load. The Journal of General Virology. 94: 817-830. PMID 23239576 DOI: 10.1099/vir.0.049171-0 |
0.501 |
|
| 2013 |
Jaramillo N, Domingo E, Muñoz-Egea MC, Tabarés E, Gadea I. Evidence of Muller's ratchet in herpes simplex virus type 1. The Journal of General Virology. 94: 366-375. PMID 23100362 DOI: 10.1099/vir.0.044685-0 |
0.411 |
|
| 2012 |
Moreno H, Grande-Pérez A, Domingo E, MartÃn V. Arenaviruses and lethal mutagenesis. Prospects for new ribavirin-based interventions. Viruses. 4: 2786-805. PMID 23202505 DOI: 10.3390/v4112786 |
0.31 |
|
| 2012 |
Domingo E, Sheldon J, Perales C. Viral Quasispecies Evolution Microbiology and Molecular Biology Reviews. 76: 159-216. PMID 22688811 DOI: 10.1128/Mmbr.05023-11 |
0.451 |
|
| 2012 |
Moreno H, Tejero H, de la Torre JC, Domingo E, MartÃn V. Mutagenesis-mediated virus extinction: virus-dependent effect of viral load on sensitivity to lethal defection. Plos One. 7: e32550. PMID 22442668 DOI: 10.1371/journal.pone.0032550 |
0.43 |
|
| 2011 |
Simmonds P, Domingo E. Virus evolution. Current Opinion in Virology. 1: 410-2. PMID 22440843 DOI: 10.1016/j.coviro.2011.10.021 |
0.317 |
|
| 2011 |
Domingo E. Paradoxical interplay of viral and cellular functions. Viruses. 3: 272-7. PMID 21994731 DOI: 10.3390/v3030272 |
0.355 |
|
| 2011 |
Ojosnegros S, Perales C, Mas A, Domingo E. Quasispecies as a matter of fact: viruses and beyond. Virus Research. 162: 203-15. PMID 21945638 DOI: 10.1016/J.Virusres.2011.09.018 |
0.331 |
|
| 2011 |
Perales C, Henry M, Domingo E, Wain-Hobson S, Vartanian J. Lethal Mutagenesis of Foot-and-Mouth Disease Virus Involves Shifts in Sequence Space Journal of Virology. 85: 12227-12240. PMID 21917974 DOI: 10.1128/Jvi.00716-11 |
0.502 |
|
| 2011 |
Perales C, Agudo R, Manrubia SC, Domingo E. Influence of mutagenesis and viral load on the sustained low-level replication of an RNA virus. Journal of Molecular Biology. 407: 60-78. PMID 21256131 DOI: 10.1016/J.Jmb.2011.01.026 |
0.43 |
|
| 2010 |
Agudo R, Ferrer-Orta C, Arias A, Higuera Idl, Perales C, Pérez-Luque R, Verdaguer N, Domingo E. A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape Plos Pathogens. 6. PMID 20865120 DOI: 10.1371/Journal.Ppat.1001072 |
0.498 |
|
| 2010 |
Ojosnegros S, Beerenwinkel N, Domingo E. Competition-colonization dynamics: An ecology approach to quasispecies dynamics and virulence evolution in RNA viruses. Communicative & Integrative Biology. 3: 333-6. PMID 20798818 DOI: 10.4161/Cib.3.4.11658 |
0.317 |
|
| 2010 |
Arias A, Perales C, Escarmís C, Domingo E. Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus. Plos One. 5. PMID 20505767 DOI: 10.1371/Journal.Pone.0010735 |
0.451 |
|
| 2010 |
Manrubia SC, Domingo E, Lázaro E. Pathways to extinction: beyond the error threshold. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 365: 1943-52. PMID 20478889 DOI: 10.1098/rstb.2010.0076 |
0.438 |
|
| 2010 |
Domingo E. Mechanisms of viral emergence. Veterinary Research. 41: 38. PMID 20167200 DOI: 10.1051/vetres/2010010 |
0.377 |
|
| 2010 |
Ojosnegros S, Beerenwinkel N, Antal T, Nowak MA, Escarmís C, Domingo E. Competition-colonization dynamics in an RNA virus. Proceedings of the National Academy of Sciences of the United States of America. 107: 2108-12. PMID 20080701 DOI: 10.1073/Pnas.0909787107 |
0.379 |
|
| 2010 |
Martín V, Abia D, Domingo E, Grande-Pérez A. An interfering activity against lymphocytic choriomeningitis virus replication associated with enhanced mutagenesis. The Journal of General Virology. 91: 990-1003. PMID 20007356 DOI: 10.1099/vir.0.017053-0 |
0.392 |
|
| 2009 |
Agudo R, Arias A, Domingo E. 5-fluorouracil in lethal mutagenesis of foot-and-mouth disease virus. Future Medicinal Chemistry. 1: 529-39. PMID 21426129 DOI: 10.4155/fmc.09.26 |
0.478 |
|
| 2009 |
Perales C, Agudo R, Tejero H, Manrubia SC, Domingo E. Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections. Plos Pathogens. 5. PMID 19911056 DOI: 10.1371/Journal.Ppat.1000658 |
0.382 |
|
| 2009 |
Escarmís C, Perales C, Domingo E. Biological Effect of Muller's Ratchet: Distant Capsid Site Can Affect Picornavirus Protein Processing Journal of Virology. 83: 6748-6756. PMID 19403672 DOI: 10.1128/Jvi.00538-09 |
0.332 |
|
| 2008 |
Cases-González C, Arribas M, Domingo E, Lázaro E. Beneficial Effects of Population Bottlenecks in an RNA Virus Evolving at Increased Error Rate Journal of Molecular Biology. 384: 1120-1129. PMID 18951905 DOI: 10.1016/j.jmb.2008.10.014 |
0.377 |
|
| 2008 |
Arias A, Arnold JJ, Sierra M, Smidansky ED, Domingo E, Cameron CE. Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin. Journal of Virology. 82: 12346-55. PMID 18829745 DOI: 10.1128/Jvi.01297-08 |
0.39 |
|
| 2008 |
Domingo E, Grande-Pérez A, Martín V. Future prospects for the treatment of rapidly evolving viral pathogens: insights from evolutionary biology. Expert Opinion On Biological Therapy. 8: 1455-60. PMID 18774914 DOI: 10.1517/14712598.8.10.1455 |
0.378 |
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| 2008 |
Sanz-Ramos M, Díaz-San Segundo F, Escarmís C, Domingo E, Sevilla N. Hidden virulence determinants in a viral quasispecies in vivo. Journal of Virology. 82: 10465-76. PMID 18715925 DOI: 10.1128/JVI.00825-08 |
0.455 |
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| 2008 |
Agudo R, Arias A, Pariente N, Perales C, Escarmís C, Jorge A, Marina A, Domingo E. Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis. Journal of Molecular Biology. 382: 652-666. PMID 18662697 DOI: 10.1016/J.Jmb.2008.07.033 |
0.42 |
|
| 2008 |
Briones C, Domingo E. Minority report: hidden memory genomes in HIV-1 quasispecies and possible clinical implications. Aids Reviews. 10: 93-109. PMID 18615120 |
0.345 |
|
| 2008 |
Martín V, Grande-Pérez A, Domingo E. No evidence of selection for mutational robustness during lethal mutagenesis of lymphocytic choriomeningitis virus. Virology. 378: 185-92. PMID 18572218 DOI: 10.1016/j.virol.2008.05.016 |
0.485 |
|
| 2008 |
Martín V, Domingo E. Influence of the mutant spectrum in viral evolution: focused selection of antigenic variants in a reconstructed viral quasispecies. Molecular Biology and Evolution. 25: 1544-54. PMID 18436553 DOI: 10.1093/molbev/msn099 |
0.387 |
|
| 2008 |
Escarmís C, Lázaro E, Arias A, Domingo E. Repeated bottleneck transfers can lead to non-cytocidal forms of a cytopathic virus: implications for viral extinction. Journal of Molecular Biology. 376: 367-79. PMID 18158159 DOI: 10.1016/j.jmb.2007.11.042 |
0.469 |
|
| 2008 |
Herrera M, Grande-Pérez A, Perales C, Domingo E. Persistence of foot-and-mouth disease virus in cell culture revisited : implications for contingency in evolution Journal of General Virology. 89: 232-244. PMID 18089747 DOI: 10.1099/Vir.0.83312-0 |
0.305 |
|
| 2007 |
García-Arriaza J, Domingo E, Briones C. Characterization of minority subpopulations in the mutant spectrum of HIV-1 quasispecies by successive specific amplifications. Virus Research. 129: 123-34. PMID 17706828 DOI: 10.1016/j.virusres.2007.07.001 |
0.341 |
|
| 2007 |
Núñez JI, Molina N, Baranowski E, Domingo E, Clark S, Burman A, Berryman S, Jackson T, Sobrino F. Guinea pig-adapted foot-and-mouth disease virus with altered receptor recognition can productively infect a natural host. Journal of Virology. 81: 8497-506. PMID 17522230 DOI: 10.1128/JVI.00340-07 |
0.313 |
|
| 2007 |
Ferrer-Orta C, Arias A, Pérez-Luque R, Escarmís C, Domingo E, Verdaguer N. Sequential structures provide insights into the fidelity of RNA replication. Proceedings of the National Academy of Sciences of the United States of America. 104: 9463-8. PMID 17517631 DOI: 10.1073/pnas.0700518104 |
0.362 |
|
| 2007 |
Perales C, Mateo R, Mateu MG, Domingo E. Insights into RNA Virus Mutant Spectrum and Lethal Mutagenesis Events: Replicative Interference and Complementation by Multiple Point Mutants Journal of Molecular Biology. 369: 985-1000. PMID 17481660 DOI: 10.1016/J.Jmb.2007.03.074 |
0.461 |
|
| 2007 |
Herrera M, García-Arriaza J, Pariente N, Escarmís C, Domingo E. Molecular basis for a lack of correlation between viral fitness and cell killing capacity. Plos Pathogens. 3: e53. PMID 17432933 DOI: 10.1371/journal.ppat.0030053 |
0.424 |
|
| 2007 |
Domingo E, Gomez J. Quasispecies and its impact on viral hepatitis. Virus Research. 127: 131-50. PMID 17349710 DOI: 10.1016/j.virusres.2007.02.001 |
0.441 |
|
| 2006 |
Martín V, Perales C, Dávila M, Domingo E. Viral fitness can influence the repertoire of virus variants selected by antibodies. Journal of Molecular Biology. 362: 44-54. PMID 16890952 DOI: 10.1016/J.Jmb.2006.06.077 |
0.373 |
|
| 2006 |
García-Arriaza J, Ojosnegros S, Dávila M, Domingo E, Escarmís C. Dynamics of mutation and recombination in a replicating population of complementing, defective viral genomes. Journal of Molecular Biology. 360: 558-72. PMID 16797586 DOI: 10.1016/j.jmb.2006.05.027 |
0.426 |
|
| 2006 |
Martín V, Perales C, Abia D, Ortíz AR, Domingo E, Briones C. Microarray-based identification of antigenic variants of foot-and-mouth disease virus: a bioinformatics quality assessment Bmc Genomics. 7: 117-117. PMID 16709242 DOI: 10.1186/1471-2164-7-117 |
0.326 |
|
| 2006 |
Costa-Mattioli M, Domingo E, Cristina J. Analysis of sequential hepatitis A virus strains reveals coexistence of distinct viral subpopulations. The Journal of General Virology. 87: 115-8. PMID 16361423 DOI: 10.1099/Vir.0.81286-0 |
0.323 |
|
| 2005 |
Greene IP, Wang E, Deardorff ER, Milleron R, Domingo E, Weaver SC. Effect of alternating passage on adaptation of sindbis virus to vertebrate and invertebrate cells. Journal of Virology. 79: 14253-60. PMID 16254360 DOI: 10.1128/Jvi.79.22.14253-14260.2005 |
0.427 |
|
| 2005 |
Arias A, Agudo R, Ferrer-Orta C, Pérez-Luque R, Airaksinen A, Brocchi E, Domingo E, Verdaguer N, Escarmís C. Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding. Journal of Molecular Biology. 353: 1021-32. PMID 16216271 DOI: 10.1016/j.jmb.2005.09.022 |
0.381 |
|
| 2005 |
Grande-Pérez A, Gómez-Mariano G, Lowenstein PR, Domingo E. Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence. Journal of Virology. 79: 10451-9. PMID 16051837 DOI: 10.1128/Jvi.79.16.10451-10459.2005 |
0.398 |
|
| 2005 |
González-López C, Gómez-Mariano G, Escarmís C, Domingo E. Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 5: 366-74. PMID 16002345 DOI: 10.1016/j.meegid.2005.05.001 |
0.459 |
|
| 2005 |
García-Arriaza J, Domingo E, Escarmís C. A segmented form of foot-and-mouth disease virus interferes with standard virus: a link between interference and competitive fitness. Virology. 335: 155-64. PMID 15840515 DOI: 10.1016/j.virol.2005.02.012 |
0.411 |
|
| 2005 |
Yuste E, Bordería AV, Domingo E, López-Galíndez C. Few mutations in the 5' leader region mediate fitness recovery of debilitated human immunodeficiency type 1 viruses. Journal of Virology. 79: 5421-7. PMID 15827156 DOI: 10.1128/JVI.79.9.5421-5427.2005 |
0.469 |
|
| 2005 |
Manrubia SC, Escarmís C, Domingo E, Lázaro E. High mutation rates, bottlenecks, and robustness of RNA viral quasispecies. Gene. 347: 273-82. PMID 15777632 DOI: 10.1016/j.gene.2004.12.033 |
0.403 |
|
| 2005 |
Grande-Pérez A, Lázaro E, Lowenstein P, Domingo E, Manrubia SC. Suppression of viral infectivity through lethal defection. Proceedings of the National Academy of Sciences of the United States of America. 102: 4448-52. PMID 15767582 DOI: 10.1073/Pnas.0408871102 |
0.399 |
|
| 2005 |
Domingo E, Escarmís C, Lázaro E, Manrubia SC. Quasispecies dynamics and RNA virus extinction. Virus Research. 107: 129-39. PMID 15649559 DOI: 10.1016/j.virusres.2004.11.003 |
0.465 |
|
| 2005 |
Perales C, Martín V, Ruiz-Jarabo CM, Domingo E. Monitoring sequence space as a test for the target of selection in viruses. Journal of Molecular Biology. 345: 451-459. PMID 15581890 DOI: 10.1016/J.Jmb.2004.10.066 |
0.412 |
|
| 2004 |
García-Arriaza J, Manrubia SC, Toja M, Domingo E, Escarmís C. Evolutionary transition toward defective RNAs that are infectious by complementation. Journal of Virology. 78: 11678-85. PMID 15479809 DOI: 10.1128/JVI.78.21.11678-11685.2004 |
0.345 |
|
| 2004 |
Ferrer-Orta C, Arias A, Perez-Luque R, Escarmís C, Domingo E, Verdaguer N. Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA. The Journal of Biological Chemistry. 279: 47212-21. PMID 15294895 DOI: 10.1074/jbc.M405465200 |
0.317 |
|
| 2004 |
Ruiz-Jarabo CM, Pariente N, Baranowski E, Dávila M, Gómez-Mariano G, Domingo E. Expansion of host-cell tropism of foot-and-mouth disease virus despite replication in a constant environment. The Journal of General Virology. 85: 2289-2297. PMID 15269370 DOI: 10.1099/vir.0.80126-0 |
0.371 |
|
| 2004 |
Pariente N, Pernas M, de la Rosa R, Gómez-Mariano G, Fernández G, Rubio A, López M, Benito JM, López-Galíndez C, Leal M, Domingo E, Martinez MA, Mas A. Long-term suppression of plasma viremia with highly active antiretroviral therapy despite virus evolution and very limited selection of drug-resistant genotypes. Journal of Medical Virology. 73: 350-61. PMID 15170628 DOI: 10.1002/jmv.20098 |
0.343 |
|
| 2004 |
González-López C, Arias A, Pariente N, Gómez-Mariano G, Domingo E. Preextinction viral RNA can interfere with infectivity. Journal of Virology. 78: 3319-24. PMID 15016853 DOI: 10.1128/jvi.78.7.3319-3324.2004 |
0.379 |
|
| 2003 |
Sánchez G, Bosch A, Gómez-Mariano G, Domingo E, Pintó RM. Evidence for quasispecies distributions in the human hepatitis A virus genome. Virology. 315: 34-42. PMID 14592757 |
0.504 |
|
| 2003 |
Lázaro E, Escarmís C, Pérez-Mercader J, Manrubia SC, Domingo E. Resistance of virus to extinction on bottleneck passages: study of a decaying and fluctuating pattern of fitness loss. Proceedings of the National Academy of Sciences of the United States of America. 100: 10830-5. PMID 12960384 DOI: 10.1073/pnas.1332668100 |
0.448 |
|
| 2003 |
Airaksinen A, Pariente N, Menéndez-Arias L, Domingo E. Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis. Virology. 311: 339-49. PMID 12842623 DOI: 10.1016/s0042-6822(03)00144-2 |
0.497 |
|
| 2003 |
Domingo E. Quasispecies and the development of new antiviral strategies. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. Progres Des Recherches Pharmaceutiques. 60: 133-58. PMID 12790341 DOI: 10.1007/978-3-0348-8012-1_4 |
0.435 |
|
| 2003 |
Pariente N, Airaksinen A, Domingo E. Mutagenesis versus inhibition in the efficiency of extinction of foot-and-mouth disease virus. Journal of Virology. 77: 7131-8. PMID 12768034 DOI: 10.1128/jvi.77.12.7131-7138.2003 |
0.462 |
|
| 2003 |
Ruiz-Jarabo CM, Ly C, Domingo E, de la Torre JC. Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV). Virology. 308: 37-47. PMID 12706088 DOI: 10.1016/S0042-6822(02)00046-6 |
0.467 |
|
| 2003 |
Domingo E, Escarmís C, Baranowski E, Ruiz-Jarabo CM, Carrillo E, Núñez JI, Sobrino F. Evolution of foot-and-mouth disease virus. Virus Research. 91: 47-63. PMID 12527437 DOI: 10.1016/s0168-1702(02)00259-9 |
0.429 |
|
| 2003 |
Tami C, Taboga O, Berinstein A, Núñez JI, Palma EL, Domingo E, Sobrino F, Carrillo E. Evidence of the coevolution of antigenicity and host cell tropism of foot-and-mouth disease virus in vivo. Journal of Virology. 77: 1219-26. PMID 12502839 |
0.369 |
|
| 2003 |
Domingo E, Baranowski E, Escarmís C, Sobrino F. Foot-and-mouth disease virus. Comparative Immunology, Microbiology and Infectious Diseases. 25: 297-308. PMID 12365806 DOI: 10.1016/s0147-9571(02)00027-9 |
0.323 |
|
| 2002 |
Quiñones-Mateu ME, Tadele M, Parera M, Mas A, Weber J, Rangel HR, Chakraborty B, Clotet B, Domingo E, Menéndez-Arias L, Martínez MA. Insertions in the reverse transcriptase increase both drug resistance and viral fitness in a human immunodeficiency virus type 1 isolate harboring the multi-nucleoside reverse transcriptase inhibitor resistance 69 insertion complex mutation. Journal of Virology. 76: 10546-52. PMID 12239335 |
0.46 |
|
| 2002 |
Lázaro E, Escarmís C, Domingo E, Manrubia SC. Modeling viral genome fitness evolution associated with serial bottleneck events: evidence of stationary states of fitness. Journal of Virology. 76: 8675-81. PMID 12163587 DOI: 10.1128/jvi.76.17.8675-8681.2002 |
0.306 |
|
| 2002 |
Escarmís C, Gómez-Mariano G, Dávila M, Lázaro E, Domingo E. Resistance to extinction of low fitness virus subjected to plaque-to-plaque transfers: diversification by mutation clustering. Journal of Molecular Biology. 315: 647-61. PMID 11812137 DOI: 10.1006/jmbi.2001.5259 |
0.432 |
|
| 2001 |
Arias A, Lázaro E, Escarmís C, Domingo E. Molecular intermediates of fitness gain of an RNA virus: characterization of a mutant spectrum by biological and molecular cloning. The Journal of General Virology. 82: 1049-1060. PMID 11297679 DOI: 10.1099/0022-1317-82-5-1049 |
0.554 |
|
| 1998 |
Elena SF, Dávila M, Novella IS, Holland JJ, Domingo E, Moya A. EVOLUTIONARY DYNAMICS OF FITNESS RECOVERY FROM THE DEBILITATING EFFECTS OF MULLER'S RATCHET. Evolution; International Journal of Organic Evolution. 52: 309-314. PMID 28568345 DOI: 10.1111/J.1558-5646.1998.Tb01633.X |
0.365 |
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