Bess Frost - Publications

Affiliations: 
Harvard Medical School/Brigham and Women's Hospital 
Area:
Neurodegeneration, epigenetics

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Whitson HE, Banks WA, Diaz MM, Frost B, Kellis M, Lathe R, Schmader KE, Spudich SS, Tanzi R, Garden G. New approaches for understanding the potential role of microbes in Alzheimer's disease. Brain, Behavior, & Immunity - Health. 36: 100743. PMID 38435720 DOI: 10.1016/j.bbih.2024.100743  0.371
2024 Atrian F, Ramirez P, De Mange J, Marquez M, Gonzalez EM, Minaya M, Karch CM, Frost B. m6A-dependent circular RNA formation mediates tau-induced neurotoxicity. Biorxiv : the Preprint Server For Biology. PMID 38328044 DOI: 10.1101/2024.01.25.577211  0.329
2023 Frost B. Alzheimer's disease and related tauopathies: disorders of disrupted neuronal identity. Trends in Neurosciences. PMID 37591720 DOI: 10.1016/j.tins.2023.07.006  0.437
2023 Beckmann A, Ramirez P, Gamez M, Gonzalez E, De Mange J, Bieniek KF, Ray WJ, Frost B. Moesin is an effector of tau-induced actin overstabilization, cell cycle activation, and neurotoxicity in Alzheimer's disease. Iscience. 26: 106152. PMID 36879821 DOI: 10.1016/j.isci.2023.106152  0.414
2023 Sohn C, Ma J, Ray WJ, Frost B. Pathogenic tau decreases nuclear tension in cultured neurons. Frontiers in Aging. 4: 1058968. PMID 36756194 DOI: 10.3389/fragi.2023.1058968  0.474
2023 Ochoa E, Ramirez P, Gonzalez E, De Mange J, Ray WJ, Bieniek KF, Frost B. Pathogenic tau-induced transposable element-derived dsRNA drives neuroinflammation. Science Advances. 9: eabq5423. PMID 36608133 DOI: 10.1126/sciadv.abq5423  0.465
2022 Levy SA, Zuniga G, Gonzalez EM, Butler D, Temple S, Frost B. Tau, an sensor of tau multimerization, identifies neuroprotective interventions in tauopathy. Cell Reports Methods. 2: 100292. PMID 36160048 DOI: 10.1016/j.crmeth.2022.100292  0.428
2022 Schulz L, Ramirez P, Lemieux A, Gonzalez E, Thomson T, Frost B. Tau-Induced Elevation of the Activity-Regulated Cytoskeleton Associated Protein Arc1 Causally Mediates Neurodegeneration in the Adult Drosophila Brain. Neuroscience. PMID 35487302 DOI: 10.1016/j.neuroscience.2022.04.017  0.437
2022 Zuniga G, Levy S, Ramirez P, De Mange J, Gonzalez E, Gamez M, Frost B. Tau-induced deficits in nonsense-mediated mRNA decay contribute to neurodegeneration. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35416419 DOI: 10.1002/alz.12653  0.322
2021 Dehkordi SK, Walker J, Sah E, Bennett E, Atrian F, Frost B, Woost B, Bennett RE, Orr TC, Zhou Y, Andhey PS, Colonna M, Sudmant PH, Xu P, Wang M, et al. Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology. Nature Aging. 1: 1107-1116. PMID 35531351 DOI: 10.1038/s43587-021-00142-3  0.373
2021 Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, ... ... Frost B, et al. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathologica. PMID 34719765 DOI: 10.1007/s00401-021-02379-z  0.426
2021 Ramirez P, Zuniga G, Sun W, Beckmann A, Ochoa E, DeVos SL, Hyman B, Chiu G, Roy ER, Cao W, Orr M, Buggia-Prevot V, Ray WJ, Frost B. Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system. Progress in Neurobiology. 102181. PMID 34670118 DOI: 10.1016/j.pneurobio.2021.102181  0.337
2021 Sexton C, Snyder H, Beher D, Boxer AL, Brannelly P, Brion JP, Buée L, Cacace AM, Chételat G, Citron M, DeVos SL, Diaz K, Feldman HH, Frost B, Goate AM, et al. Current directions in tau research: Highlights from Tau 2020. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34581500 DOI: 10.1002/alz.12452  0.337
2021 Mozolewski P, Jeziorek M, Schuster CM, Bading H, Frost B, Dobrowolski R. The role of nuclear Ca2+ in maintaining neuronal homeostasis and brain health. Journal of Cell Science. 134. PMID 33912918 DOI: 10.1242/jcs.254904  0.312
2020 Lohr KM, Frost B, Scherzer C, Feany MB. Biotin rescues mitochondrial dysfunction and neurotoxicity in a tauopathy model. Proceedings of the National Academy of Sciences of the United States of America. PMID 33318181 DOI: 10.1073/pnas.1922392117  0.713
2020 Mahoney R, Ochoa Thomas E, Ramirez P, Miller HE, Beckmann A, Zuniga G, Dobrowolski R, Frost B. Pathogenic Tau Causes a Toxic Depletion of Nuclear Calcium. Cell Reports. 32: 107900. PMID 32668249 DOI: 10.1016/J.Celrep.2020.107900  0.475
2020 Ochoa Thomas E, Zuniga G, Sun W, Frost B. Awakening the dark side: retrotransposon activation in neurodegenerative disorders. Current Opinion in Neurobiology. 61: 65-72. PMID 32092528 DOI: 10.1016/J.Conb.2020.01.012  0.353
2018 Cornelison GL, Levy SA, Jenson T, Frost B. Tau-induced nuclear envelope invagination causes a toxic accumulation of mRNA in Drosophila. Aging Cell. e12847. PMID 30411463 DOI: 10.1111/Acel.12847  0.39
2018 Sun W, Samimi H, Gamez M, Zare H, Frost B. Pathogenic tau-induced piRNA depletion promotes neuronal death through transposable element dysregulation in neurodegenerative tauopathies. Nature Neuroscience. 21: 1038-1048. PMID 30038280 DOI: 10.1038/S41593-018-0194-1  0.448
2018 Beckmann PA, Zare H, Frost B. P3-177: Investigating The Loss Of Terminal Neuronal Differentiation As A Novel Mechanism Driving Neuronal Death In Alzheimer'S Disease And Related Tauopathies Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1535  0.46
2017 Orr ME, Sullivan AC, Frost B. A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies. Trends in Pharmacological Sciences. PMID 28455089 DOI: 10.1016/J.Tips.2017.03.011  0.545
2016 Frost B. Alzheimer's Disease: An Acquired Neurodegenerative Laminopathy. Nucleus (Austin, Tex.). 0. PMID 27167528 DOI: 10.1080/19491034.2016.1183859  0.526
2015 Frost B, Bardai FH, Feany MB. Lamin Dysfunction Mediates Neurodegeneration in Tauopathies. Current Biology : Cb. PMID 26725200 DOI: 10.1016/J.Cub.2015.11.039  0.643
2015 Frost B, Götz J, Feany MB. Connecting the dots between tau dysfunction and neurodegeneration. Trends in Cell Biology. 25: 46-53. PMID 25172552 DOI: 10.1016/J.Tcb.2014.07.005  0.697
2014 Merlo P, Frost B, Peng S, Yang YJ, Park PJ, Feany M. p53 prevents neurodegeneration by regulating synaptic genes. Proceedings of the National Academy of Sciences of the United States of America. 111: 18055-60. PMID 25453105 DOI: 10.1073/Pnas.1419083111  0.617
2014 Frost B, Hemberg M, Lewis J, Feany MB. Tau promotes neurodegeneration through global chromatin relaxation. Nature Neuroscience. 17: 357-66. PMID 24464041 DOI: 10.1038/Nn.3639  0.713
2010 Frost B, Diamond MI. Prion-like mechanisms in neurodegenerative diseases. Nature Reviews. Neuroscience. 11: 155-9. PMID 20029438 DOI: 10.1038/Nrn2786  0.639
2009 Frost B, Diamond MI. The expanding realm of prion phenomena in neurodegenerative disease. Prion. 3: 74-7. PMID 19448400 DOI: 10.4161/Pri.3.2.8754  0.631
2009 Frost B, Jacks RL, Diamond MI. Propagation of tau misfolding from the outside to the inside of a cell. The Journal of Biological Chemistry. 284: 12845-52. PMID 19282288 DOI: 10.1074/Jbc.M808759200  0.657
2009 Frost B, Ollesch J, Wille H, Diamond MI. Conformational diversity of wild-type Tau fibrils specified by templated conformation change. The Journal of Biological Chemistry. 284: 3546-51. PMID 19010781 DOI: 10.1074/Jbc.M805627200  0.626
Show low-probability matches.