Marc Diamond, M.D. - Publications

Neurology Washington University School of Medicine, St. Louis, MO, United States 

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Eskandari-Sedighi G, Daude N, Gapeshina H, Sanders DW, Kamali-Jamil R, Yang J, Shi B, Wille H, Ghetti B, Diamond MI, Janus C, Westaway D. The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition. Molecular Neurodegeneration. 12: 72. PMID 28978354 DOI: 10.1186/s13024-017-0215-7  0.4
2016 Sanders DW, Kaufman SK, Holmes BB, Diamond MI. Prions and Protein Assemblies that Convey Biological Information in Health and Disease. Neuron. 89: 433-48. PMID 26844828 DOI: 10.1016/j.neuron.2016.01.026  1
2015 Schindler SE, McCall JG, Yan P, Hyrc KL, Li M, Tucker CL, Lee JM, Bruchas MR, Diamond MI. Photo-activatable Cre recombinase regulates gene expression in vivo. Scientific Reports. 5: 13627. PMID 26350769 DOI: 10.1038/srep13627  1
2015 Funk KE, Mirbaha H, Jiang H, Holtzman DM, Diamond MI. Distinct Therapeutic Mechanisms of Tau Antibodies: Promoting Microglial Clearance Versus Blocking Neuronal Uptake. The Journal of Biological Chemistry. 290: 21652-62. PMID 26126828 DOI: 10.1074/jbc.M115.657924  1
2015 Mirbaha H, Holmes BB, Sanders DW, Bieschke J, Diamond MI. Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation. The Journal of Biological Chemistry. 290: 14893-903. PMID 25887395 DOI: 10.1074/jbc.M115.652693  1
2015 Diamond MI, Cai S, Boudreau A, Carey CJ, Lyle N, Pappu RV, Swamidass SJ, Bissell M, Piwnica-Worms H, Shao J. Subcellular localization and Ser-137 phosphorylation regulate tumor-suppressive activity of profilin-1. The Journal of Biological Chemistry. 290: 9075-86. PMID 25681442 DOI: 10.1074/jbc.M114.619874  1
2015 Gu X, Cantle JP, Greiner ER, Lee CY, Barth AM, Gao F, Park CS, Zhang Z, Sandoval-Miller S, Zhang RL, Diamond M, Mody I, Coppola G, Yang XW. N17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic mice. Neuron. 85: 726-41. PMID 25661181 DOI: 10.1016/j.neuron.2015.01.008  1
2015 Wobst HJ, Sharma A, Diamond MI, Wanker EE, Bieschke J. The green tea polyphenol (-)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios. Febs Letters. 589: 77-83. PMID 25436420 DOI: 10.1016/j.febslet.2014.11.026  1
2014 Holmes BB, Furman JL, Mahan TE, Yamasaki TR, Mirbaha H, Eades WC, Belaygorod L, Cairns NJ, Holtzman DM, Diamond MI. Proteopathic tau seeding predicts tauopathy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 111: E4376-85. PMID 25261551 DOI: 10.1073/pnas.1411649111  1
2014 Kim W, Jones JO, Diamond M, Haqq C, Molina A, Small EJ, Ryan CJ. Inhibition of the androgen receptor by mineralocorticoids at levels physiologically achieved in serum in patients treated with abiraterone acetate. Prostate Cancer and Prostatic Diseases. 17: 292-9. PMID 25047002 DOI: 10.1038/pcan.2014.27  1
2014 Holmes BB, Diamond MI. Prion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic target. The Journal of Biological Chemistry. 289: 19855-61. PMID 24860099 DOI: 10.1074/jbc.R114.549295  1
2014 Sanders DW, Kaufman SK, DeVos SL, Sharma AM, Mirbaha H, Li A, Barker SJ, Foley AC, Thorpe JR, Serpell LC, Miller TM, Grinberg LT, Seeley WW, Diamond MI. Distinct tau prion strains propagate in cells and mice and define different tauopathies. Neuron. 82: 1271-88. PMID 24857020 DOI: 10.1016/j.neuron.2014.04.047  1
2014 Udan-Johns M, Bengoechea R, Bell S, Shao J, Diamond MI, True HL, Weihl CC, Baloh RH. Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones. Human Molecular Genetics. 23: 157-70. PMID 23962724 DOI: 10.1093/hmg/ddt408  1
2013 Schindler SE, McConathy J, Ances BM, Diamond MI. Advances in diagnostic testing for Alzheimer disease. Missouri Medicine. 110: 401-5. PMID 24279191  1
2013 Yanamandra K, Kfoury N, Jiang H, Mahan TE, Ma S, Maloney SE, Wozniak DF, Diamond MI, Holtzman DM. Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo. Neuron. 80: 402-14. PMID 24075978 DOI: 10.1016/j.neuron.2013.07.046  1
2013 Holmes BB, DeVos SL, Kfoury N, Li M, Jacks R, Yanamandra K, Ouidja MO, Brodsky FM, Marasa J, Bagchi DP, Kotzbauer PT, Miller TM, Papy-Garcia D, Diamond MI. Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds. Proceedings of the National Academy of Sciences of the United States of America. 110: E3138-47. PMID 23898162 DOI: 10.1073/pnas.1301440110  1
2013 Kaufman SK, Diamond MI. Prion-like propagation of protein aggregation and related therapeutic strategies. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 371-82. PMID 23801258 DOI: 10.1007/s13311-013-0196-3  1
2013 Diamond MI. A strong consensus has emerged around the role of protein misfolding and aggregation in the pathogenesis of neurodegeneration. Introduction. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 369-70. PMID 23794177 DOI: 10.1007/s13311-013-0197-2  1
2013 Walker LC, Diamond MI, Duff KE, Hyman BT. Mechanisms of protein seeding in neurodegenerative diseases. Jama Neurology. 70: 304-10. PMID 23599928 DOI: 10.1001/jamaneurol.2013.1453  1
2013 Li M, Yasumura D, Ma AA, Matthes MT, Yang H, Nielson G, Huang Y, Szoka FC, Lavail MM, Diamond MI. Intravitreal administration of HA-1077, a ROCK inhibitor, improves retinal function in a mouse model of huntington disease. Plos One. 8: e56026. PMID 23409115 DOI: 10.1371/journal.pone.0056026  1
2013 Zheng Z, Li A, Holmes BB, Marasa JC, Diamond MI. An N-terminal nuclear export signal regulates trafficking and aggregation of Huntingtin (Htt) protein exon 1. The Journal of Biological Chemistry. 288: 6063-71. PMID 23319588 DOI: 10.1074/jbc.M112.413575  1
2012 Holmes BB, Diamond MI. Amyotrophic lateral sclerosis and organ donation: is there risk of disease transmission? Annals of Neurology. 72: 832-6. PMID 23280834 DOI: 10.1002/ana.23684  1
2012 Holmes BB, Diamond MI. Cellular mechanisms of protein aggregate propagation. Current Opinion in Neurology. 25: 721-6. PMID 23108252 DOI: 10.1097/WCO.0b013e32835a3ee0  1
2012 Zheng Z, Diamond MI. Huntington disease and the huntingtin protein. Progress in Molecular Biology and Translational Science. 107: 189-214. PMID 22482451 DOI: 10.1016/B978-0-12-385883-2.00010-2  1
2012 Shao J, Diamond MI. Protein phosphatase 1 dephosphorylates profilin-1 at Ser-137. Plos One. 7: e32802. PMID 22479341 DOI: 10.1371/journal.pone.0032802  1
2012 Kfoury N, Holmes BB, Jiang H, Holtzman DM, Diamond MI. Trans-cellular propagation of Tau aggregation by fibrillar species. The Journal of Biological Chemistry. 287: 19440-51. PMID 22461630 DOI: 10.1074/jbc.M112.346072  1
2012 Fuentealba RA, Marasa J, Diamond MI, Piwnica-Worms D, Weihl CC. An aggregation sensing reporter identifies leflunomide and teriflunomide as polyglutamine aggregate inhibitors. Human Molecular Genetics. 21: 664-80. PMID 22052286 DOI: 10.1093/hmg/ddr500  1
2011 Yamada K, Cirrito JR, Stewart FR, Jiang H, Finn MB, Holmes BB, Binder LI, Mandelkow EM, Diamond MI, Lee VM, Holtzman DM. In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13110-7. PMID 21917794 DOI: 10.1523/JNEUROSCI.2569-11.2011  1
2010 Fuentealba RA, Udan M, Bell S, Wegorzewska I, Shao J, Diamond MI, Weihl CC, Baloh RH. Interaction with polyglutamine aggregates reveals a Q/N-rich domain in TDP-43. The Journal of Biological Chemistry. 285: 26304-14. PMID 20554523 DOI: 10.1074/jbc.M110.125039  1
2010 Angeli S, Shao J, Diamond MI. F-actin binding regions on the androgen receptor and huntingtin increase aggregation and alter aggregate characteristics. Plos One. 5: e9053. PMID 20140226 DOI: 10.1371/journal.pone.0009053  1
2010 Frost B, Diamond MI. Prion-like mechanisms in neurodegenerative diseases. Nature Reviews. Neuroscience. 11: 155-9. PMID 20029438 DOI: 10.1038/nrn2786  1
2009 Li M, Huang Y, Ma AA, Lin E, Diamond MI. Y-27632 improves rotarod performance and reduces huntingtin levels in R6/2 mice. Neurobiology of Disease. 36: 413-20. PMID 19591939 DOI: 10.1016/j.nbd.2009.06.011  1
2009 Frost B, Diamond MI. The expanding realm of prion phenomena in neurodegenerative disease. Prion. 3: 74-7. PMID 19448400  1
2009 Jones JO, Bolton EC, Huang Y, Feau C, Guy RK, Yamamoto KR, Hann B, Diamond MI. Non-competitive androgen receptor inhibition in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 7233-8. PMID 19363158 DOI: 10.1073/pnas.0807282106  1
2009 Frost B, Jacks RL, Diamond MI. Propagation of tau misfolding from the outside to the inside of a cell. The Journal of Biological Chemistry. 284: 12845-52. PMID 19282288 DOI: 10.1074/jbc.M808759200  1
2009 Gerber AN, Masuno K, Diamond MI. Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening. Proceedings of the National Academy of Sciences of the United States of America. 106: 4929-34. PMID 19255438 DOI: 10.1073/pnas.0812308106  1
2009 Jones JO, An WF, Diamond MI. AR inhibitors identified by high-throughput microscopy detection of conformational change and subcellular localization. Acs Chemical Biology. 4: 199-208. PMID 19236099 DOI: 10.1021/cb900024z  1
2009 Frost B, Ollesch J, Wille H, Diamond MI. Conformational diversity of wild-type Tau fibrils specified by templated conformation change. The Journal of Biological Chemistry. 284: 3546-51. PMID 19010781 DOI: 10.1074/jbc.M805627200  1
2008 Chandra S, Shao J, Li JX, Li M, Longo FM, Diamond MI. A common motif targets huntingtin and the androgen receptor to the proteasome. The Journal of Biological Chemistry. 283: 23950-5. PMID 18586675 DOI: 10.1074/jbc.M800467200  1
2008 Jones JO, Diamond MI. A cellular conformation-based screen for androgen receptor inhibitors. Acs Chemical Biology. 3: 412-8. PMID 18582038 DOI: 10.1021/cb800054w  1
2008 Shao J, Welch WJ, Diprospero NA, Diamond MI. Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation. Molecular and Cellular Biology. 28: 5196-208. PMID 18573880 DOI: 10.1128/MCB.00079-08  1
2008 Ryan CJ, Zavodovskaya M, Youngren JF, Campbell M, Diamond M, Jones J, Shiry L, Allan G, Maddux BA, Goldfine ID. Inhibitory effects of nordihydroguaiaretic acid (NDGA) on the IGF-1 receptor and androgen dependent growth of LAPC-4 prostate cancer cells. The Prostate. 68: 1232-40. PMID 18491370 DOI: 10.1002/pros.20789  1
2008 Shao J, Welch WJ, Diamond MI. ROCK and PRK-2 mediate the inhibitory effect of Y-27632 on polyglutamine aggregation. Febs Letters. 582: 1637-42. PMID 18423405 DOI: 10.1016/j.febslet.2008.04.009  1
2007 Jones JO, Diamond MI. Design and implementation of cell-based assays to model human disease. Acs Chemical Biology. 2: 718-24. PMID 18030988 DOI: 10.1021/cb700177u  1
2007 Shao J, Diamond MI. Polyglutamine diseases: emerging concepts in pathogenesis and therapy. Human Molecular Genetics. 16: R115-23. PMID 17911155 DOI: 10.1093/hmg/ddm213  1
2007 Li M, Chevalier-Larsen ES, Merry DE, Diamond MI. Soluble androgen receptor oligomers underlie pathology in a mouse model of spinobulbar muscular atrophy. The Journal of Biological Chemistry. 282: 3157-64. PMID 17121819 DOI: 10.1074/jbc.M609972200  1
2007 Cvoro A, Paruthiyil S, Jones JO, Tzagarakis-Foster C, Clegg NJ, Tatomer D, Medina RT, Tagliaferri M, Schaufele F, Scanlan TS, Diamond MI, Cohen I, Leitman DC. Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extract. Endocrinology. 148: 538-47. PMID 17095596 DOI: 10.1210/en.2006-0803  1
2006 Desai UA, Pallos J, Ma AA, Stockwell BR, Thompson LM, Marsh JL, Diamond MI. Biologically active molecules that reduce polyglutamine aggregation and toxicity. Human Molecular Genetics. 15: 2114-24. PMID 16720620 DOI: 10.1093/hmg/ddl135  1
2005 Schaufele F, Carbonell X, Guerbadot M, Borngraeber S, Chapman MS, Ma AA, Miner JN, Diamond MI. The structural basis of androgen receptor activation: intramolecular and intermolecular amino-carboxy interactions. Proceedings of the National Academy of Sciences of the United States of America. 102: 9802-7. PMID 15994236 DOI: 10.1073/pnas.0408819102  1
2003 Pollitt SK, Pallos J, Shao J, Desai UA, Ma AA, Thompson LM, Marsh JL, Diamond MI. A rapid cellular FRET assay of polyglutamine aggregation identifies a novel inhibitor. Neuron. 40: 685-94. PMID 14622574 DOI: 10.1016/S0896-6273(03)00697-4  1
2003 Cowan KJ, Diamond MI, Welch WJ. Polyglutamine protein aggregation and toxicity are linked to the cellular stress response. Human Molecular Genetics. 12: 1377-91. PMID 12783846  1
2001 Welch WJ, Diamond MI. Glucocorticoid modulation of androgen receptor nuclear aggregation and cellular toxicity is associated with distinct forms of soluble expanded polyglutamine protein. Human Molecular Genetics. 10: 3063-74. PMID 11751688  1
2000 Diamond MI, Robinson MR, Yamamoto KR. Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor. Proceedings of the National Academy of Sciences of the United States of America. 97: 657-61. PMID 10639135 DOI: 10.1073/pnas.97.2.657  1
1991 Miner JN, Diamond MI, Yamamoto KR. Joints in the regulatory lattice: composite regulation by steroid receptor-AP1 complexes. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 2: 525-30. PMID 1751408  1
1990 Diamond MI, Miner JN, Yoshinaga SK, Yamamoto KR. Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. Science (New York, N.Y.). 249: 1266-72. PMID 2119054  1
1990 Boylan KB, Takahashi N, Paty DW, Sadovnick AD, Diamond M, Hood LE, Prusiner SB. DNA length polymorphism 5' to the myelin basic protein gene is associated with multiple sclerosis. Annals of Neurology. 27: 291-7. PMID 1691612 DOI: 10.1002/ana.410270311  1
1987 Boylan KB, Takahashi N, Diamond M, Hood LE, Prusiner SB. DNA length polymorphism located 5' to the human myelin basic protein gene. American Journal of Human Genetics. 40: 387-400. PMID 2437796  1
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