Jonathan M Gibbins - Publications

Affiliations: 
Institute for Cardiovascular and Metabolic Research University of Reading, Earley, England, United Kingdom 

187 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bozbas E, Zhou R, Soyama S, Allen-Redpath K, Mitchell JL, Fisk HL, Calder PC, Jones C, Gibbins JM, Fischer R, Hester S, Yaqoob P. Dietary n-3 polyunsaturated fatty acids alter the number, fatty acid profile and coagulatory activity of circulating and platelet-derived extracellular vesicles: a randomized, controlled crossover trial. The American Journal of Clinical Nutrition. PMID 38484976 DOI: 10.1016/j.ajcnut.2024.03.008  0.503
2024 Authi KS, Khan S, Gibbins JM, Brain SD. Evidence that inositol 1,4,5-trisphosphate 3-kinase and inositol 1,3,4,5-tetrakisphosphate are negative regulators of platelet function. Research and Practice in Thrombosis and Haemostasis. 8: 102326. PMID 38404940 DOI: 10.1016/j.rpth.2024.102326  0.572
2024 Provenzale I, Solari FA, Schönichen C, Brouns SLN, Fernández DI, Kuijpers MJE, van der Meijden PEJ, Gibbins JM, Sickmann A, Jones C, Heemskerk JWM. Endothelium-mediated regulation of platelet activation: Involvement of multiple protein kinases. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 38: e23468. PMID 38334433 DOI: 10.1096/fj.202300360RR  0.714
2023 Seefried L, Alzahrani A, Arango Sancho P, Bacchetta J, Crowley R, Emma F, Gibbins J, Grandone A, Javaid MK, Mindler G, Raimann A, Rothenbuhler A, Tucker I, Zeitlin L, Linglart A. XLH Matters 2022: Insights and recommendations to improve outcomes for people living with X-linked hypophosphataemia (XLH). Orphanet Journal of Rare Diseases. 18: 333. PMID 37885021 DOI: 10.1186/s13023-023-02883-3  0.429
2023 Mitchell JL, Khan D, Rana RH, Kriek N, Unsworth AJ, Sage T, Bye AP, Laffan M, Shapiro S, Thakurta A, Grech H, Ramasamy K, Gibbins JM. Multiple myeloma and its treatment contribute to increased platelet reactivity. Platelets. 34: 2264940. PMID 37822056 DOI: 10.1080/09537104.2023.2264940  0.666
2023 AlOuda SK, Sasikumar P, AlThunayan T, Alaajam F, Khan S, Sahli KA, Abohassan MS, Pollitt A, Jung SM, Gibbins JM. Role of heat shock protein 47 in platelet glycoprotein VI dimerization and signaling. Research and Practice in Thrombosis and Haemostasis. 7: 102177. PMID 37767064 DOI: 10.1016/j.rpth.2023.102177  0.685
2023 Geyer CE, Chen HJ, Bye AP, Manz XD, Guerra D, Caniels TG, Bijl TP, Griffith GR, Hoepel W, de Taeye SW, Veth J, Vlaar AP, Vidarsson G, Bogaard HJ, Aman J, ... Gibbins JM, et al. Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19. Life Science Alliance. 6. PMID 37699657 DOI: 10.26508/lsa.202302106  0.528
2023 Provenzale I, De Simone I, Gibbins JM, Heemskerk JWM, van der Meijden PEJ, Jones CI. Regulation of Glycoprotein VI-Dependent Platelet Activation and Thrombus Formation by Heparan Sulfate Proteoglycan Perlecan. International Journal of Molecular Sciences. 24. PMID 37686158 DOI: 10.3390/ijms241713352  0.723
2023 Mitchell JL, Little G, Bye AP, Gaspar RS, Unsworth AJ, Kriek N, Sage T, Stainer A, Sangowawa I, Morrow GB, Bastos RN, Shapiro S, Desborough MJR, Curry N, Gibbins JM, et al. Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability. Research and Practice in Thrombosis and Haemostasis. 7: 100200. PMID 37601014 DOI: 10.1016/j.rpth.2023.100200  0.84
2023 Kuravi SJ, Ahmed NS, Taylor KA, Capes EM, Bye A, Unsworth AJ, Gibbins JM, Pugh N. Delineating Zinc Influx Mechanisms during Platelet Activation. International Journal of Molecular Sciences. 24. PMID 37511448 DOI: 10.3390/ijms241411689  0.672
2023 Ranjbar J, Njoroge W, Gibbins JM, Roach P, Yang Y, Harper AGS. Developing Biomimetic Hydrogels of the Arterial Wall as a Prothrombotic Substrate for In Vitro Human Thrombosis Models. Gels (Basel, Switzerland). 9. PMID 37367147 DOI: 10.3390/gels9060477  0.57
2023 Gibbins JM. Adding fuel to the flames in preeclampsia: the platelet connection. Journal of Thrombosis and Haemostasis : Jth. 21: 1750-1752. PMID 37330264 DOI: 10.1016/j.jtha.2023.03.031  0.58
2023 Mitchell JL, Dunster JL, Kriek N, Unsworth AJ, Sage T, Mohammed YMM, De Simone I, Taylor KA, Bye AP, Ólafsson G, Brunton M, Mark S, Dymott LD, Whyte A, Ruparelia N, ... ... Gibbins JM, et al. The rate of platelet activation determines thrombus size and structure at arterial shear. Journal of Thrombosis and Haemostasis : Jth. PMID 37085037 DOI: 10.1016/j.jtha.2023.03.044  0.695
2023 Thienel M, Müller-Reif JB, Zhang Z, Ehreiser V, Huth J, Shchurovska K, Kilani B, Schweizer L, Geyer PE, Zwiebel M, Novotny J, Lüsebrink E, Little G, Orban M, Nicolai L, ... ... Gibbins JM, et al. Immobility-associated thromboprotection is conserved across mammalian species from bear to human. Science (New York, N.Y.). 380: 178-187. PMID 37053338 DOI: 10.1126/science.abo5044  0.561
2023 Tantiwong C, Dunster JL, Cavill R, Tomlinson MG, Wierling C, Heemskerk JWM, Gibbins JM. An agent-based approach for modelling and simulation of glycoprotein VI receptor diffusion, localisation and dimerisation in platelet lipid rafts. Scientific Reports. 13: 3906. PMID 36890261 DOI: 10.1038/s41598-023-30884-6  0.535
2023 De Simone I, Baaten CCFMJ, Gibbins JM, Ten Cate H, Heemskerk JWM, Jones CI, van der Meijden PEJ. Repeated platelet activation and the potential of previously activated platelets to contribute to thrombus formation. Journal of Thrombosis and Haemostasis : Jth. PMID 36754678 DOI: 10.1016/j.jtha.2023.01.006  0.69
2022 Bye AP, Kriek N, Sage T, Rawlings SJ, Prodger C, Kesavan M, Lees C, Booth S, Cowen LG, Shefferd K, Desborough MJ, Gibbins JM, Eyre TA. Pirtobrutinib results in reversible platelet dysfunction compared to ibrutinib and acalabrutinib. Haematologica. PMID 36519322 DOI: 10.3324/haematol.2022.281402  0.694
2022 Waller AK, Birch K, Gibbins JM, Clarke SR. Activation of Human Platelets by Secreted Protease Staphopain A. Pathogens (Basel, Switzerland). 11. PMID 36364988 DOI: 10.3390/pathogens11111237  0.714
2022 Dunster JL, Gibbins JM, Nelson MR. Exploring the constituent mechanisms of hepatitis: a dynamical systems approach. Mathematical Medicine and Biology : a Journal of the Ima. PMID 36197900 DOI: 10.1093/imammb/dqac013  0.466
2022 De Simone I, Baaten CCFMJ, Jandrot-Perrus M, Gibbins JM, Ten Cate H, Heemskerk JWM, Jones CI, van der Meijden PEJ. Coagulation Factor XIIIa and Activated Protein C Activate Platelets via GPVI and PAR1. International Journal of Molecular Sciences. 23. PMID 36142125 DOI: 10.3390/ijms231810203  0.718
2022 Kempster C, Butler G, Kuznecova E, Taylor KA, Kriek N, Little G, Sowa MA, Sage T, Johnson LJ, Gibbins JM, Pollitt AY. Fully automated platelet differential interference contrast image analysis via deep learning. Scientific Reports. 12: 4614. PMID 35301400 DOI: 10.1038/s41598-022-08613-2  0.68
2022 Kriek N, Nock S, Sage T, Khalifa B, Bye A, Mitchell JL, Thomson S, McLaughlin MG, Jones S, Gibbins JM, Unsworth A. Cucurbitacins elicit anti-platelet activity via perturbation of the actin cytoskeleton and integrin function. Thrombosis and Haemostasis. PMID 35253142 DOI: 10.1055/a-1788-5322  0.704
2021 Savarirayan R, Ireland P, Irving M, Thompson D, Alves I, Baratela WAR, Betts J, Bober MB, Boero S, Briddell J, Campbell J, Campeau PM, Carl-Innig P, Cheung MS, Cobourne M, ... ... Gibbins J, et al. International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia. Nature Reviews. Endocrinology. PMID 34837063 DOI: 10.1038/s41574-021-00595-x  0.463
2021 Dunster JL, Mitchell JL, Mohammed YMM, Taylor KA, Gibbins JM, Jones CI. Kinetx: A Combined Flow Cytometry Assay and Analysis Software Framework to Quantitatively Measure and Categorize Platelet Activation in Real-time. Journal of Visualized Experiments : Jove. PMID 34694288 DOI: 10.3791/62947  0.681
2021 Downes K, Zhao X, Gleadall NS, McKinney H, Kempster C, Batista J, Thomas P, Cooper M, Michael JV, Kreuzhuber R, Wedderburn K, Waller K, Varney B, Verdier H, Kriek N, ... ... Gibbins JM, et al. G protein-coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1. Blood Advances. PMID 34581777 DOI: 10.1182/bloodadvances.2021005453  0.701
2021 Dunster JL, Bye AP, Kriek N, Sage T, Mitchell JL, Kempster C, Batista J, McKinney H, Thomas P, Jones CI, Downes K, Unsworth AJ, Gibbins JM. Multi-parameter phenotyping of platelet reactivity for stratification of human cohorts. Blood Advances. PMID 34474473 DOI: 10.1182/bloodadvances.2020003261  0.702
2021 Cai H, Sasikumar P, Little G, Bihan D, Hamaia SW, Zhou A, Gibbins JM, Farndale RW. Identification of HSP47 Binding Site on Native Collagen and Its Implications for the Development of HSP47 Inhibitors. Biomolecules. 11. PMID 34356607 DOI: 10.3390/biom11070983  0.498
2021 Wright JR, Jones S, Parvathy S, Kaczmarek LK, Forsythe I, Farndale RW, Gibbins JM, Mahaut-Smith MP. The voltage-gated K channel Kv1.3 modulates platelet motility and αβ integrin-dependent adhesion to collagen. Platelets. 1-11. PMID 34348571 DOI: 10.1080/09537104.2021.1942818  0.691
2021 Bye AP, Hoepel W, Mitchell JL, Jégouic SM, Loureiro S, Sage T, Vidarsson G, Nouta J, Wuhrer M, de Taeye SW, van Gils M, Kriek N, Cooper N, Jones I, den Dunnen J, ... Gibbins JM, et al. Aberrant glycosylation of anti-SARS-CoV-2 IgG is a pro-thrombotic stimulus for platelets. Blood. PMID 34315173 DOI: 10.1182/blood.2021011871  0.645
2021 Gaspar RS, Mansilla S, Vieira VA, da Silva LB, Gibbins JM, Castro L, Trostchansky A, Marcus de A Paes A. The protein disulphide isomerase inhibitor CxxCpep modulates oxidative burst and mitochondrial function in platelets. Free Radical Biology & Medicine. PMID 34252541 DOI: 10.1016/j.freeradbiomed.2021.07.011  0.824
2021 Gaspar RS, Mansilla S, Vieira VA, da Silva LB, Gibbins JM, Castro L, Trostchansky A, Marcus de A Paes A. The protein disulphide isomerase inhibitor CxxCpep modulates oxidative burst and mitochondrial function in platelets. Free Radical Biology & Medicine. PMID 34252541 DOI: 10.1016/j.freeradbiomed.2021.07.011  0.824
2021 Gaspar RS, Gibbins JM. Thiol isomerases orchestrate thrombosis and haemostasis. Antioxidants & Redox Signaling. PMID 33940944 DOI: 10.1089/ars.2021.0086  0.832
2021 Taylor KA, Little G, Gibbins JM. Mind the gap: connexins and pannexins in platelet function. Platelets. 1-7. PMID 33818243 DOI: 10.1080/09537104.2021.1902971  0.585
2021 Gaspar RS, Sage T, Little G, Kriek N, Pula G, Gibbins JM. Protein Disulphide Isomerase and NADPH Oxidase 1 Cooperate to Control Platelet Function and Are Associated with Cardiometabolic Disease Risk Factors. Antioxidants (Basel, Switzerland). 10. PMID 33806982 DOI: 10.3390/antiox10030497  0.817
2021 Soriano Jerez EM, Gibbins JM, Hughes CE. Targeting platelet inhibition receptors for novel therapies: PECAM-1 and G6b-B. Platelets. 1-9. PMID 33646086 DOI: 10.1080/09537104.2021.1882668  0.686
2021 Gaspar RS, Ferreira P, Mitchell JL, Pula G, Gibbins JM. Platelet-derived extracellular vesicles express NADPH oxidase-1 (Nox-1), generate superoxide and modulate platelet function. Free Radical Biology & Medicine. PMID 33548451 DOI: 10.1016/j.freeradbiomed.2021.01.051  0.845
2021 Gaspar RS, Unsworth AJ, Al-Dibouni A, Bye AP, Sage T, Stewart M, Wells S, Cox RD, Gibbins JM, Sellayah D, E Hughes C. Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring. Scientific Reports. 11: 1473. PMID 33446734 DOI: 10.1038/s41598-020-80373-3  0.773
2021 Majeed KR, Al-Fahad D, Jalood HH, Hantosh HA, Ali MK, Sakthivel S, Williams HF, Gibbins JM, Patel K, Baksh MF, Vaiyapuri S. RhD blood type significantly influences susceptibility to contract COVID-19 among a study population in Iraq F1000research. 10: 38. DOI: 10.12688/F1000RESEARCH.27777.1  0.491
2021 Gwozdz A, Black S, Morris R, Messiha S, Ikram M, Bye A, Gibbins J, Rand M, Patel A, Modarai B, Smith A, Saha P. Investigating a Role for Platelets in Venous In-Stent Stenosis in Patients with Post-Thrombotic Syndrome Journal of Vascular Surgery: Venous and Lymphatic Disorders. 9: 549. DOI: 10.1016/J.JVSV.2020.12.037  0.599
2020 Ferreira PM, Bozbas E, Tannetta SD, Alroqaiba N, Zhou R, Crawley JTB, Gibbins JM, Jones CI, Ahnström J, Yaqoob P. Mode of induction of platelet-derived extracellular vesicles is a critical determinant of their phenotype and function. Scientific Reports. 10: 18061. PMID 33093473 DOI: 10.1038/s41598-020-73005-3  0.661
2020 Holbrook LM, Keeton SJ, Sasikumar P, Nock S, Gelzinis J, Brunt E, Ryan S, Pantos MM, Verbetsky CA, Gibbins JM, Kennedy DR. Zafirlukast is a broad-spectrum thiol isomerase inhibitor that inhibits thrombosis without altering bleeding times. British Journal of Pharmacology. PMID 33080041 DOI: 10.1111/bph.15291  0.629
2020 Sahli K, Flora GD, Sasikumar P, Maghrabi AH, Holbrook LM, AlOuda SK, Elgheznawy A, Sage T, Stainer AR, Adiyaman R, AboHassan M, Crescente M, Kriek N, Vaiyapuri S, Bye AP, ... ... Gibbins JM, et al. Structural, Functional and Mechanistic Insights Uncover the Fundamental Role of Orphan Connexin62 in Platelets. Blood. PMID 32822477 DOI: 10.1182/blood.2019004575  0.643
2020 Mazet F, Tindall MJ, Gibbins JM, Fry MJ. A model of the PI cycle reveals the regulating roles of lipid-binding proteins and pitfalls of using mosaic biological data. Scientific Reports. 10: 13244. PMID 32764630 DOI: 10.1038/s41598-020-70215-7  0.517
2020 Al-Dibouni A, Gaspar R, Ige S, Boateng S, Cagampang FR, Gibbins J, Cox RD, Sellayah D. Unique Genetic and Histological Signatures of Mouse Pericardial Adipose Tissue. Nutrients. 12. PMID 32580292 DOI: 10.3390/Nu12061855  0.446
2020 Unsworth AJ, Bye AP, Sage T, Gaspar RS, Eaton N, Drew C, Stainer A, Kriek N, Volberding PJ, Hutchinson JL, Riley R, Jones S, Mundell SJ, Cui W, Falet H, ... Gibbins JM, et al. Anti-platelet properties of Pim kinase inhibition is mediated through disruption of thromboxane A2 receptor signalling. Haematologica. PMID 32467143 DOI: 10.3324/haematol.2019.223529  0.804
2020 Martyanov AA, Balabin FA, Dunster JL, Panteleev MA, Gibbins JM, Sveshnikova AN. Control of Platelet CLEC-2-Mediated Activation by Receptor Clustering and Tyrosine Kinase Signaling. Biophysical Journal. 118: 2641-2655. PMID 32396849 DOI: 10.1016/j.bpj.2020.04.023  0.681
2020 Lopes-Pires ME, Ahmed NS, Vara D, Gibbins JM, Pula G, Pugh N. Zinc regulates reactive oxygen species generation in platelets. Platelets. 1-10. PMID 32248725 DOI: 10.1080/09537104.2020.1742311  0.671
2020 Bye AP, Gibbins JM, Mahaut-Smith MP. Ca waves coordinate purinergic receptor-evoked integrin activation and polarization. Science Signaling. 13. PMID 31964805 DOI: 10.1126/scisignal.aav7354  0.532
2020 Darling TK, Schenk MP, Zhou CC, Maloba FM, Mimche PN, Gibbins JM, Jobe SM, Lamb TJ. Platelet α-granules contribute to organ-specific pathologies in a mouse model of severe malaria. Blood Advances. 4: 1-8. PMID 31891656 DOI: 10.1182/bloodadvances.2019000773  0.584
2020 Khan D, Mitchell J, Rana R, Kriek N, Unsworth A, Sage T, Laffan M, Shapiro S, Thakurta A, Ramasamy K, Gibbins J. Prospective Study Reveals Increased Platelet Function Associated with Multiple Myeloma and Its Treatment Blood. 136: 21-21. DOI: 10.1182/blood-2020-140821  0.673
2020 Mansilla S, Gaspar R, Vieira VA, Bezerra da Silva L, Gibbins J, Castro L, Paes A, Trostchansky A. Platelet ROS Generation and Mitochondrial Function are Modulated by the Protein Disulfide Isomerase-targeted Peptide CxxCpep Free Radical Biology and Medicine. 159: S70. DOI: 10.1016/j.freeradbiomed.2020.10.184  0.574
2019 Gaspar RS, da Silva SA, Stapleton J, Fontelles JLL, Sousa HR, Chagas VT, Alsufyani S, Trostchansky A, Gibbins JM, Paes AMA. Myricetin, the Main Flavonoid in Leaf, Is a Novel Inhibitor of Platelet Thiol Isomerases PDI and ERp5. Frontiers in Pharmacology. 10: 1678. PMID 32116678 DOI: 10.3389/fphar.2019.01678  0.789
2019 Flora GD, Sahli KA, Sasikumar P, Holbrook LM, Stainer AR, AlOuda SK, Crescente M, Sage T, Unsworth AJ, Gibbins JM. Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis. Scientific Reports. 9: 17210. PMID 31748641 DOI: 10.1038/s41598-019-53218-x  0.691
2019 Dunster JL, Unsworth AJ, Bye AP, Haining EJ, Sowa MA, Di Y, Sage T, Pallini C, Pike JA, Hardy AT, Nieswandt B, García Á, Watson SP, Poulter NS, Gibbins JM, et al. Interspecies differences in protein expression do not impact the spatiotemporal regulation of GPVI mediated activation. Journal of Thrombosis and Haemostasis : Jth. PMID 31680418 DOI: 10.1111/jth.14673  0.657
2019 Stainer AR, Sasikumar P, Bye AP, Unsworth AJ, Holbrook LM, Tindall M, Lovegrove JA, Gibbins JM. The Metabolites of the Dietary Flavonoid Quercetin Possess Potent Antithrombotic Activity, and Interact with Aspirin to Enhance Antiplatelet Effects. Th Open : Companion Journal to Thrombosis and Haemostasis. 3: e244-e258. PMID 31367693 DOI: 10.1055/s-0039-1694028  0.651
2019 Salamah MF, Ravishankar D, Vaiyapuri R, Moraes LA, Patel K, Perretti M, Gibbins JM, Vaiyapuri S. The formyl peptide fMLF primes platelet activation and augments thrombus formation. Journal of Thrombosis and Haemostasis : Jth. PMID 31033193 DOI: 10.1111/jth.14466  0.564
2019 Waller AK, Lantos L, Sammut A, Salgin B, McKinney H, Foster HR, Kriek N, Gibbins JM, Stanworth SJ, Garner SF, Venkatesh V, Curley A, Belteki G, Ghevaert C. Flow cytometry for near-patient testing in premature neonates reveals variation in platelet function: a novel approach to guide platelet transfusion. Pediatric Research. PMID 30742030 DOI: 10.1038/s41390-019-0316-9  0.676
2019 Macwan AS, Boknäs N, Ntzouni MP, Ramström S, Gibbins JM, Faxälv L, Lindahl TL. Gradient-dependent inhibition of stimulatory signaling from platelet G protein-coupled receptors. Haematologica. PMID 30630981 DOI: 10.3324/haematol.2018.205815  0.682
2019 Unsworth AJ, Bye AP, Kriek N, Sage T, Osborne AA, Donaghy D, Gibbins JM. Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction. Platelets. 30: 762-772. PMID 30252580 DOI: 10.1080/09537104.2018.1514107  0.709
2018 Salamah MF, Ravishankar D, Kodji X, Moraes LA, Williams HF, Vallance TM, Albadawi DA, Vaiyapuri R, Watson K, Gibbins JM, Brain SD, Perretti M, Vaiyapuri S. The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation. Blood Advances. 2: 2973-2985. PMID 30413433 DOI: 10.1182/bloodadvances.2018021758  0.684
2018 Belyaev AV, Dunster JL, Gibbins JM, Panteleev MA, Volpert V. Advancing research on blood coagulation and thrombosis: Reply to the comments on "Modeling thrombosis in silico: Frontiers, challenges, unresolved problems and milestones". Physics of Life Reviews. PMID 30297158 DOI: 10.1016/j.plrev.2018.09.006  0.503
2018 Dunster JL, Panteleev MA, Gibbins JM, Sveshnikova AN. Mathematical Techniques for Understanding Platelet Regulation and the Development of New Pharmacological Approaches. Methods in Molecular Biology (Clifton, N.J.). 1812: 255-279. PMID 30171583 DOI: 10.1007/978-1-4939-8585-2_15  0.58
2018 Bye AP, Unsworth AJ, Gibbins JM. Screening and High-Throughput Platelet Assays. Methods in Molecular Biology (Clifton, N.J.). 1812: 81-94. PMID 30171573 DOI: 10.1007/978-1-4939-8585-2_5  0.633
2018 Stefanini L, Lee RH, Paul DS, O'Shaughnessy EC, Ghalloussi D, Jones CI, Boulaftali Y, Poe KO, Piatt R, Kechele DO, Caron KM, Hahn KM, Gibbins JM, Bergmeier W. Functional redundancy between RAP1 isoforms in murine platelet production and function. Blood. PMID 30131434 DOI: 10.1182/Blood-2018-03-838714  0.723
2018 Bye AP, Gibbins JM. Move along, nothing to see here: Btk inhibitors stop platelets sticking to plaques. Journal of Thrombosis and Haemostasis : Jth. PMID 30030898 DOI: 10.1111/jth.14201  0.681
2018 Huang Z, Barker D, Gibbins JM, Dash PR. Talin is a substrate for SUMOylation in migrating cancer cells. Experimental Cell Research. PMID 30003879 DOI: 10.1016/j.yexcr.2018.07.005  0.529
2018 Molica F, Figueroa XF, Kwak BR, Isakson BE, Gibbins JM. Connexins and Pannexins in Vascular Function and Disease. International Journal of Molecular Sciences. 19. PMID 29874791 DOI: 10.3390/Ijms19061663  0.509
2018 Fuentes E, Gibbins JM, Holbrook LM, Palomo I. NADPH oxidase 2 (NOX2): A key target of oxidative stress-mediated platelet activation and thrombosis. Trends in Cardiovascular Medicine. PMID 29661712 DOI: 10.1016/j.tcm.2018.03.001  0.664
2018 Belyaev AV, Dunster JL, Gibbins JM, Panteleev MA, Volpert V. Modeling thrombosis in silico: Frontiers, challenges, unresolved problems and milestones. Physics of Life Reviews. PMID 29550179 DOI: 10.1016/j.plrev.2018.02.005  0.598
2018 Sasikumar P, AlOuda KS, Kaiser WJ, Holbrook LM, Kriek N, Unsworth JA, Bye AP, Sage T, Ushioda R, Nagata K, Farndale RW, Gibbins JM. The Chaperone Protein HSP47: A Platelet Collagen Binding Protein that Contributes to Thrombosis and Haemostasis. Journal of Thrombosis and Haemostasis : Jth. PMID 29512284 DOI: 10.1111/Jth.13998  0.626
2018 Unsworth AJ, Flora GD, Gibbins JM. Non-genomic effects of nuclear receptors: insights from the anucleate platelet. Cardiovascular Research. 114: 645-655. PMID 29452349 DOI: 10.1093/cvr/cvy044  0.581
2018 Holbrook LM, Sandhar GK, Sasikumar P, Schenk MP, Stainer AR, Sahli KA, Flora GD, Bicknell AB, Gibbins JM. A humanized monoclonal antibody that inhibits platelet-surface ERp72 reveals a role for ERp72 in thrombosis. Journal of Thrombosis and Haemostasis : Jth. 16: 367-377. PMID 29052936 DOI: 10.1111/jth.13878  0.649
2018 Gibbins J, Rana R, Khan D, Shapiro S, Grech H, Ramasamy K. Multiple Myeloma Treatment Is Associated with Enhanced Platelet Reactivity Blood. 132: 3300-3300. DOI: 10.1182/BLOOD-2018-99-116006  0.671
2017 Bye AP, Unsworth AJ, Desborough MJ, Hildyard CAT, Appleby N, Bruce D, Kriek N, Nock SH, Sage T, Hughes CE, Gibbins JM. Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib. Blood Advances. 1: 2610-2623. PMID 29296914 DOI: 10.1182/bloodadvances.2017011999  0.706
2017 Lopes Pires ME, Clarke SR, Marcondes S, Gibbins JM. Lipopolysaccharide potentiates platelet responses via toll-like receptor 4-stimulated Akt-Erk-PLA2 signalling. Plos One. 12: e0186981. PMID 29136006 DOI: 10.1371/journal.pone.0186981  0.635
2017 Ravishankar D, Salamah M, Attina A, Pothi R, Vallance TM, Javed M, Williams HF, Alzahrani EMS, Kabova E, Vaiyapuri R, Shankland K, Gibbins J, Strohfeldt K, Greco F, Osborn HMI, et al. Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy. Scientific Reports. 7: 5738. PMID 28720875 DOI: 10.1038/s41598-017-05936-3  0.685
2017 Unsworth AJ, Bye AP, Tannetta DS, Desborough MJR, Kriek N, Sage T, Allan HE, Crescente M, Yaqoob P, Warner TD, Jones CI, Gibbins JM. Farnesoid X Receptor and Liver X Receptor Ligands Initiate Formation of Coated Platelets. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28619996 DOI: 10.1161/ATVBAHA.117.309135  0.625
2017 Ilkan Z, Wright JR, Goodall AH, Gibbins JM, Jones CI, Mahaut-Smith MP. Evidence for Shear-mediated Ca(2+) Entry Through Mechanosensitive Cation Channels in Human Platelets and a Megakaryocytic Cell Line. The Journal of Biological Chemistry. PMID 28416610 DOI: 10.1074/jbc.M116.766196  0.61
2017 Unsworth AJ, Flora GD, Sasikumar P, Bye AP, Sage T, Kriek N, Crescente M, Gibbins JM. RXR Ligands Negatively Regulate Thrombosis and Hemostasis. Arteriosclerosis, Thrombosis, and Vascular Biology. 37: 812-822. PMID 28254816 DOI: 10.1161/ATVBAHA.117.309207  0.682
2017 Williams HF, Vaiyapuri R, Gajjeraman P, Hutchinson G, Gibbins JM, Bicknell A, Vaiyapuri S. Challenges in diagnosing and treating snakebites in a rural population of Tamil Nadu, India: The views of clinicians. Toxicon : Official Journal of the International Society On Toxinology. PMID 28238804 DOI: 10.1016/j.toxicon.2017.02.025  0.445
2017 Unsworth AJ, Kriek N, Bye AP, Naran K, Sage T, Flora GD, Gibbins JM. PPARγ agonists negatively regulate αIIbβ3 integrin outside-in signaling and platelet function through up-regulation of protein kinase A activity. Journal of Thrombosis and Haemostasis : Jth. 15: 356-369. PMID 27896950 DOI: 10.1111/jth.13578  0.653
2017 Gibbins J, Pollitt A, Jones C, Hughes C, Vaiyapuri S. European Platelet Summer School: A Biochemical Society Supported Independent Meeting The Biochemist. 39: 53. DOI: 10.1042/bio03906053  0.595
2016 Moraes LA, Unsworth AJ, Vaiyapuri S, Ali MS, Sasikumar P, Sage T, Flora GD, Bye AP, Kriek N, Dorchies E, Molendi-Coste O, Dombrowicz D, Staels B, Bishop-Bailey D, Gibbins JM. Farnesoid X Receptor and Its Ligands Inhibit the Function of Platelets. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27758768 DOI: 10.1161/Atvbaha.116.308093  0.649
2016 Crescente M, Pluthero FG, Li L, Lo RW, Walsh TG, Louriero S, Ali MS, Vaiyapuri S, Schenk MP, Holbrook LM, Falet H, Jones IM, Poole AW, Kahr WH, Gibbins JM. Intracellular Trafficking, Localization, and Mobilization of Platelet-Borne Thiol Isomerases. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27079884 DOI: 10.1161/ATVBAHA.116.307461  0.698
2016 Gibbins JM. Platelets stop us leaking. Blood. 127: 1528-9. PMID 27013214 DOI: 10.1182/blood-2016-01-692186  0.671
2016 Bye AP, Unsworth AJ, Gibbins JM. Platelet signaling: a complex interplay between inhibitory and activatory networks. Journal of Thrombosis and Haemostasis : Jth. 14: 918-30. PMID 26929147 DOI: 10.1111/jth.13302  0.677
2015 Mazet F, Dunster JL, Jones CI, Vaiyapuri S, Tindall MJ, Fry MJ, Gibbins JM. A high-density immunoblotting methodology for quantification of total protein levels and phosphorylation modifications. Scientific Reports. 5: 16995. PMID 26592927 DOI: 10.1038/srep16995  0.541
2015 Dunster JL, Mazet F, Fry MJ, Gibbins JM, Tindall MJ. Regulation of Early Steps of GPVI Signal Transduction by Phosphatases: A Systems Biology Approach. Plos Computational Biology. 11: e1004589. PMID 26584182 DOI: 10.1371/journal.pcbi.1004589  0.619
2015 Tannetta DS, Hunt K, Jones CI, Davidson N, Coxon CH, Ferguson D, Redman CW, Gibbins JM, Sargent IL, Tucker KL. Syncytiotrophoblast Extracellular Vesicles from Pre-Eclampsia Placentas Differentially Affect Platelet Function. Plos One. 10: e0142538. PMID 26551971 DOI: 10.1371/Journal.Pone.0142538  0.66
2015 Bye AP, Unsworth AJ, Vaiyapuri S, Stainer AR, Fry MJ, Gibbins JM. Ibrutinib Inhibits Platelet Integrin αIIbβ3 Outside-In Signaling and Thrombus Stability But Not Adhesion to Collagen. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 2326-35. PMID 26359510 DOI: 10.1161/ATVBAHA.115.306130  0.683
2015 Wright B, Watson KA, McGuffin LJ, Lovegrove JA, Gibbins JM. GRID and docking analyses reveal a molecular basis for flavonoid inhibition of Src family kinase activity. The Journal of Nutritional Biochemistry. PMID 26140983 DOI: 10.1016/j.jnutbio.2015.05.004  0.544
2015 Vaiyapuri S, Flora GD, Gibbins JM. Gap junctions and connexin hemichannels in the regulation of haemostasis and thrombosis. Biochemical Society Transactions. 43: 489-94. PMID 26009196 DOI: 10.1042/BST20150055  0.688
2015 Vaiyapuri S, Roweth H, Ali MS, Unsworth AJ, Stainer AR, Flora GD, Crescente M, Jones CI, Moraes LA, Gibbins JM. Pharmacological actions of nobiletin in the modulation of platelet function. British Journal of Pharmacology. 172: 4133-45. PMID 25988959 DOI: 10.1111/bph.13191  0.688
2015 Vaiyapuri S, Sage T, Rana RH, Schenk MP, Ali MS, Unsworth AJ, Jones CI, Stainer AR, Kriek N, Moraes LA, Gibbins JM. EphB2 regulates contact-dependent and contact-independent signaling to control platelet function. Blood. 125: 720-30. PMID 25370417 DOI: 10.1182/blood-2014-06-585083  0.701
2014 Taylor L, Vasudevan SR, Jones CI, Gibbins JM, Churchill GC, Campbell RD, Coxon CH. Discovery of novel GPVI receptor antagonists by structure-based repurposing. Plos One. 9: e101209. PMID 24971515 DOI: 10.1371/Journal.Pone.0101209  0.65
2014 Jones CI, Sage T, Moraes LA, Vaiyapuri S, Hussain U, Tucker KL, Barrett NE, Gibbins JM. Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin αIIbβ3. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1968-76. PMID 24969778 DOI: 10.1161/Atvbaha.114.304097  0.702
2014 Jones CI, Tucker KL, Sasikumar P, Sage T, Kaiser WJ, Moore C, Emerson M, Gibbins JM. Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi. Journal of Thrombosis and Haemostasis : Jth. 12: 1342-52. PMID 24888521 DOI: 10.1111/Jth.12620  0.706
2014 Dannoura A, Giraldo A, Pereira I, Gibbins JM, Dash PR, Bicknell KA, Brooks G. Ibuprofen inhibits migration and proliferation of human coronary artery smooth muscle cells by inducing a differentiated phenotype: role of peroxisome proliferator-activated receptor γ. The Journal of Pharmacy and Pharmacology. 66: 779-92. PMID 24438071 DOI: 10.1111/jphp.12203  0.5
2014 Ambily A, Kaiser WJ, Pierro C, Chamberlain EV, Li Z, Jones CI, Kassouf N, Gibbins JM, Authi KS. The role of plasma membrane STIM1 and Ca2+entry in platelet aggregation. STIM1 binds to novel proteins in human platelets Cellular Signalling. 26: 502-511. PMID 24308967 DOI: 10.1016/J.Cellsig.2013.11.025  0.635
2014 Stainer A, Lovegrove J, Gibbins J. THE RELATIONSHIP BETWEEN THE METABOLITES OF THE DIETARY FLAVONOID QUERCETIN AND HAEMOSTASIS, THROMBOSIS AND PLATELET FUNCTION Heart. 100: A15.4-A16. DOI: 10.1136/heartjnl-2014-306916.47  0.663
2014 Dunster J, Mazet F, Tindall M, Fry MJ, Gibbins JM. THE ROLE OF PHOSPHATASES IN REGULATING GPVI SIGNAL TRANSDUCTION: A SYSTEMS BIOLOGY APPROACH Heart. 100: A14.3-A15. DOI: 10.1136/heartjnl-2014-306916.43  0.481
2013 Wright B, Tindall MJ, Lovegrove JA, Gibbins JM. Investigating flavonoids as molecular templates for the design of small-molecule inhibitors of cell signaling. Journal of Food Science. 78: N1921-8. PMID 24329957 DOI: 10.1111/1750-3841.12293  0.559
2013 Vaiyapuri S, Vaiyapuri R, Ashokan R, Ramasamy K, Nattamaisundar K, Jeyaraj A, Chandran V, Gajjeraman P, Baksh MF, Gibbins JM, Hutchinson EG. Snakebite and its socio-economic impact on the rural population of Tamil Nadu, India. Plos One. 8: e80090. PMID 24278244 DOI: 10.1371/journal.pone.0080090  0.447
2013 Gibbins JM. Platelets using proteins creatively. Blood. 122: 3553-4. PMID 24263955 DOI: 10.1182/blood-2013-09-527663  0.676
2013 Vaiyapuri S, Ali MS, Moraes LA, Sage T, Lewis KR, Jones CI, Gibbins JM. Tangeretin regulates platelet function through inhibition of phosphoinositide 3-kinase and cyclic nucleotide signaling. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2740-9. PMID 24135020 DOI: 10.1161/ATVBAHA.113.301988  0.655
2013 Wright B, Spencer JP, Lovegrove JA, Gibbins JM. Flavonoid inhibitory pharmacodynamics on platelet function in physiological environments. Food & Function. 4: 1803-10. PMID 24121953 DOI: 10.1039/c3fo60272a  0.647
2013 Vaiyapuri S, Moraes LA, Sage T, Ali MS, Lewis KR, Mahaut-Smith MP, Oviedo-Orta E, Simon AM, Gibbins JM. Connexin40 regulates platelet function. Nature Communications. 4: 2564. PMID 24096827 DOI: 10.1038/ncomms3564  0.712
2013 Moraes LA, Vaiyapuri S, Sasikumar P, Ali MS, Kriek N, Sage T, Gibbins JM. Antithrombotic actions of statins involve PECAM-1 signaling. Blood. 122: 3188-96. PMID 24030383 DOI: 10.1182/blood-2013-04-491845  0.712
2013 Waller AK, Sage T, Kumar C, Carr T, Gibbins JM, Clarke SR. Staphylococcus aureus lipoteichoic acid inhibits platelet activation and thrombus formation via the Paf receptor. The Journal of Infectious Diseases. 208: 2046-57. PMID 23911710 DOI: 10.1093/infdis/jit398  0.708
2013 Kim K, Hahm E, Li J, Holbrook LM, Sasikumar P, Stanley RG, Ushio-Fukai M, Gibbins JM, Cho J. Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice. Blood. 122: 1052-61. PMID 23788140 DOI: 10.1182/Blood-2013-03-492504  0.719
2013 Wright B, Stanley RG, Kaiser WJ, Gibbins JM. The integration of proteomics and systems approaches to map regulatory mechanisms underpinning platelet function. Proteomics. Clinical Applications. 7: 144-54. PMID 23184887 DOI: 10.1002/Prca.201200095  0.688
2013 Wright B, Spencer JP, Lovegrove JA, Gibbins JM. Insights into dietary flavonoids as molecular templates for the design of anti-platelet drugs. Cardiovascular Research. 97: 13-22. PMID 23024269 DOI: 10.1093/cvr/cvs304  0.57
2013 Gibbins J, Steinhardt K, Beinart H. A systematic review of qualitative studies exploring the experience of parents whose child is diagnosed and treated for cancer. Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses. 29: 253-71. PMID 22907681 DOI: 10.1177/1043454212452791  0.447
2012 Vaiyapuri S, Thiyagarajan N, Hutchinson EG, Gibbins JM. Sequence and phylogenetic analysis of viper venom serine proteases. Bioinformation. 8: 763-72. PMID 23055627 DOI: 10.6026/97320630008763  0.493
2012 Vaiyapuri S, Hutchinson EG, Ali MS, Dannoura A, Stanley RG, Harrison RA, Bicknell AB, Gibbins JM. Rhinocetin, a venom-derived integrin-specific antagonist inhibits collagen-induced platelet and endothelial cell functions. The Journal of Biological Chemistry. 287: 26235-44. PMID 22689571 DOI: 10.1074/jbc.M112.381483  0.697
2012 Bertling A, Niemann S, Hussain M, Holbrook L, Stanley RG, Brodde MF, Pohl S, Schifferdecker T, Roth J, Jurk K, Müller A, Lahav J, Peters G, Heilmann C, Gibbins JM, et al. Staphylococcal extracellular adherence protein induces platelet activation by stimulation of thiol isomerases. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1979-90. PMID 22539594 DOI: 10.1161/ATVBAHA.112.246249  0.711
2012 Vaiyapuri S, Jones CI, Sasikumar P, Moraes LA, Munger SJ, Wright JR, Ali MS, Sage T, Kaiser WJ, Tucker KL, Stain CJ, Bye AP, Jones S, Oviedo-Orta E, Simon AM, ... ... Gibbins JM, et al. Gap junctions and connexin hemichannels underpin hemostasis and thrombosis. Circulation. 125: 2479-91. PMID 22528526 DOI: 10.1161/Circulationaha.112.101246  0.565
2012 Gibbins JM. JAMming the signals. Blood. 119: 3197-8. PMID 22493215 DOI: 10.1182/blood-2012-02-409060  0.643
2012 Holbrook LM, Sasikumar P, Stanley RG, Simmonds AD, Bicknell AB, Gibbins JM. The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function. Journal of Thrombosis and Haemostasis : Jth. 10: 278-88. PMID 22168334 DOI: 10.1111/j.1538-7836.2011.04593.x  0.668
2012 Jones CI, Barrett NE, Moraes LA, Gibbins JM, Jackson DE. Endogenous inhibitory mechanisms and the regulation of platelet function. Methods in Molecular Biology (Clifton, N.J.). 788: 341-66. PMID 22130718 DOI: 10.1007/978-1-61779-307-3_23  0.683
2012 Tucker KL, Sage T, Gibbins JM. Clot retraction. Methods in Molecular Biology (Clifton, N.J.). 788: 101-7. PMID 22130703 DOI: 10.1007/978-1-61779-307-3_8  0.666
2012 Jones CI, Moraes LA, Gibbins JM. Regulation of platelet biology by platelet endothelial cell adhesion molecule-1. Platelets. 23: 331-5. PMID 22035359 DOI: 10.3109/09537104.2011.626091  0.706
2012 Coxon CH, Lewis AM, Sadler AJ, Vasudevan SR, Thomas A, Dundas KA, Taylor L, Campbell RD, Gibbins JM, Churchill GC, Tucker KL. NAADP regulates human platelet function. The Biochemical Journal. 441: 435-42. PMID 21967541 DOI: 10.1042/Bj20111175  0.679
2012 Mitchell HL, Gibbins JM, Griffin BA, Lovegrove JA, Stowell JD, Foot E. Food and health forum meeting - nutritional approaches to cardiovascular health: Workshop report Nutrition Bulletin. 37: 270-284. DOI: 10.1111/j.1467-3010.2012.01984.x  0.437
2011 Wright B, Stanley RG, Kaiser WJ, Mills DJ, Gibbins JM. Analysis of protein networks in resting and collagen receptor (GPVI)-stimulated platelet sub-proteomes. Proteomics. 11: 4588-92. PMID 22114104 DOI: 10.1002/Pmic.201100410  0.636
2011 Vaiyapuri S, Wagstaff SC, Harrison RA, Gibbins JM, Hutchinson EG. Evolutionary analysis of novel serine proteases in the venom gland transcriptome of Bitis gabonica rhinoceros. Plos One. 6: e21532. PMID 21731776 DOI: 10.1371/journal.pone.0021532  0.518
2011 Spyridon M, Moraes LA, Jones CI, Sage T, Sasikumar P, Bucci G, Gibbins JM. LXR as a novel antithrombotic target. Blood. 117: 5751-61. PMID 21411760 DOI: 10.1182/blood-2010-09-306142  0.693
2011 Passam FH, Lin L, Huang M, Gibbins JM, Furie B, Furie BC. Role of Thiol Isomerase ERp5 in Thrombus Formation Blood. 118: 370-370. DOI: 10.1182/Blood.V118.21.370.370  0.576
2011 Stanley RG, Tucker KL, Barrett NE, Gibbins JM. Platelets and their Role in Thrombotic and Cardiovascular Disease: The Impact of Proteomic Analysis Platelet Proteomics: Principles, Analysis, and Applications. 1-26. DOI: 10.1002/9780470940297.ch1  0.679
2010 Moraes LA, Barrett NE, Jones CI, Holbrook LM, Spyridon M, Sage T, Newman DK, Gibbins JM. Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells. Journal of Thrombosis and Haemostasis : Jth. 8: 2530-41. PMID 20723025 DOI: 10.1111/j.1538-7836.2010.04025.x  0.674
2010 Vaiyapuri S, Wagstaff SC, Watson KA, Harrison RA, Gibbins JM, Hutchinson EG. Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros. Plos Neglected Tropical Diseases. 4: e796. PMID 20706583 DOI: 10.1371/journal.pntd.0000796  0.497
2010 Glen A, Evans CA, Gan CS, Cross SS, Hamdy FC, Gibbins J, Lippitt J, Eaton CL, Noirel J, Wright PC, Rehman I. Eight-plex iTRAQ analysis of variant metastatic human prostate cancer cells identifies candidate biomarkers of progression: An exploratory study. The Prostate. 70: 1313-32. PMID 20623638 DOI: 10.1002/pros.21167  0.44
2010 Wright B, Gibson T, Spencer J, Lovegrove JA, Gibbins JM. Platelet-mediated metabolism of the common dietary flavonoid, quercetin. Plos One. 5: e9673. PMID 20300638 DOI: 10.1371/journal.pone.0009673  0.634
2010 Vaiyapuri S, Harrison RA, Bicknell AB, Gibbins JM, Hutchinson G. Purification and functional characterisation of rhinocerase, a novel serine protease from the venom of Bitis gabonica rhinoceros. Plos One. 5: e9687. PMID 20300193 DOI: 10.1371/journal.pone.0009687  0.553
2010 Wright B, Moraes LA, Kemp CF, Mullen W, Crozier A, Lovegrove JA, Gibbins JM. A structural basis for the inhibition of collagen-stimulated platelet function by quercetin and structurally related flavonoids. British Journal of Pharmacology. 159: 1312-25. PMID 20148891 DOI: 10.1111/j.1476-5381.2009.00632.x  0.651
2010 Moraes LA, Spyridon M, Kaiser WJ, Jones CI, Sage T, Atherton REL, Gibbins JM. Non-genomic effects of PPARγ ligands: Inhibition of GPVI-stimulated platelet activation Journal of Thrombosis and Haemostasis. 8: 577-587. PMID 20040043 DOI: 10.1111/J.1538-7836.2009.03732.X  0.696
2010 Holbrook LM, Watkins NA, Simmonds AD, Jones CI, Ouwehand WH, Gibbins JM. Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation. British Journal of Haematology. 148: 627-37. PMID 19995400 DOI: 10.1111/j.1365-2141.2009.07994.x  0.705
2010 Kaiser WJ, Sage T, Sasikumar P, Kemp F, Pugh N, Dobson L, Holbrook L, Gibbins JM. Heat Shock Protein 47: A New Platelet Collagen Receptor Blood. 116: 158-158. DOI: 10.1182/Blood.V116.21.158.158  0.679
2009 Jones CI, Garner SF, Moraes LA, Kaiser WJ, Rankin A, Ouwehand WH, Goodall AH, Gibbins JM. PECAM-1 expression and activity negatively regulate multiple platelet signaling pathways. Febs Letters. 583: 3618-24. PMID 19850043 DOI: 10.1016/J.Febslet.2009.10.037  0.712
2009 Tucker KL, Kaiser WJ, Bergeron AL, Hu H, Dong JF, Tan TH, Gibbins JM. Proteomic analysis of resting and thrombin-stimulated platelets reveals the translocation and functional relevance of HIP-55 in platelets. Proteomics. 9: 4340-54. PMID 19725075 DOI: 10.1002/Pmic.200900024  0.696
2009 Kaiser WJ, Holbrook LM, Tucker KL, Stanley RG, Gibbins JM. A functional proteomic method for the enrichment of peripheral membrane proteins reveals the collagen binding protein Hsp47 is exposed on the surface of activated human platelets. Journal of Proteome Research. 8: 2903-14. PMID 19341245 DOI: 10.1021/Pr900027J  0.682
2009 Gibbins JM. Tweaking the gain on platelet regulation: the tachykinin connection. Atherosclerosis. 206: 1-7. PMID 19150714 DOI: 10.1016/j.atherosclerosis.2008.12.010  0.729
2009 Holbrook L, Jones K, Watkins N, Ouwehand W, Gibbins JM. Characterisation of novel platelet surface thiol isomerase enzymes Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 153: S160-S161. DOI: 10.1016/j.cbpa.2009.04.325  0.612
2008 Tucker KL, Sage T, Stevens JM, Jordan PA, Jones S, Barrett NE, St-Arnaud R, Frampton J, Dedhar S, Gibbins JM. A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion. Blood. 112: 4523-31. PMID 18772455 DOI: 10.1182/Blood-2008-03-148502  0.699
2008 Barrett NE, Holbrook L, Jones S, Kaiser WJ, Moraes LA, Rana R, Sage T, Stanley RG, Tucker KL, Wright B, Gibbins JM. Future innovations in anti-platelet therapies. British Journal of Pharmacology. 154: 918-39. PMID 18587441 DOI: 10.1038/Bjp.2008.151  0.694
2008 Jones S, Gibbins JM. The neurokinin 1 receptor: a potential new target for anti-platelet therapy? Current Opinion in Pharmacology. 8: 114-9. PMID 18296119 DOI: 10.1016/j.coph.2008.01.004  0.665
2008 Jones S, Tucker KL, Sage T, Kaiser WJ, Barrett NE, Lowry PJ, Zimmer A, Hunt SP, Emerson M, Gibbins JM. Peripheral tachykinins and the neurokinin receptor NK1 are required for platelet thrombus formation. Blood. 111: 605-12. PMID 17895403 DOI: 10.1182/Blood-2007-07-103424  0.683
2007 Guerrero JA, Navarro-Nuñez L, Lozano ML, Martínez C, Vicente V, Gibbins JM, Rivera J. Flavonoids inhibit the platelet TxA(2) signalling pathway and antagonize TxA(2) receptors (TP) in platelets and smooth muscle cells. British Journal of Clinical Pharmacology. 64: 133-44. PMID 17425630 DOI: 10.1111/j.1365-2125.2007.02881.x  0.685
2007 Gumireddy K, Sun F, Klein-Szanto AJ, Gibbins JM, Gimotty PA, Saunders AJ, Schultz PG, Huang Q. In vivo selection for metastasis promoting genes in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 104: 6696-701. PMID 17420453 DOI: 10.1073/Pnas.0701145104  0.499
2007 Moraes LA, Swales KE, Wray JA, Damazo A, Gibbins JM, Warner TD, Bishop-Bailey D. Nongenomic signaling of the retinoid X receptor through binding and inhibiting Gq in human platelets. Blood. 109: 3741-4. PMID 17213293 DOI: 10.1182/Blood-2006-05-022566  0.631
2007 Tucker KL, Stevens JM, Jordan PA, Sage T, Jones S, Barrett NE, St-Arnaud R, Frampton J, Dedhar S, Gibbins JM. Integrin Linked Kinase Is Important in Platelet Signalling and Function. Blood. 110: 420-420. DOI: 10.1182/Blood.V110.11.420.420  0.696
2006 Hubbard GP, Wolffram S, de Vos R, Bovy A, Gibbins JM, Lovegrove JA. Ingestion of onion soup high in quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in man: a pilot study. The British Journal of Nutrition. 96: 482-8. PMID 16925853  0.673
2006 Patel B, Sharifi M, Milward AD, Oberprieler NG, Gibbins JM, Parkin S, Naseem KM. Platelet nitric oxide synthase is activated by tyrosine dephosphorylation: possible role for SHP-1 phosphatase. Journal of Thrombosis and Haemostasis : Jth. 4: 2423-32. PMID 16898954 DOI: 10.1111/j.1538-7836.2006.02160.x  0.614
2006 Jordan PA, Gibbins JM. Extracellular disulfide exchange and the regulation of cellular function. Antioxidants & Redox Signaling. 8: 312-24. PMID 16677077 DOI: 10.1089/ars.2006.8.312  0.593
2006 Falati S, Patil S, Gross PL, Stapleton M, Merrill-Skoloff G, Barrett NE, Pixton KL, Weiler H, Cooley B, Newman DK, Newman PJ, Furie BC, Furie B, Gibbins JM. Platelet PECAM-1 inhibits thrombus formation in vivo Blood. 107: 535-541. PMID 16166583 DOI: 10.1182/Blood-2005-04-1512  0.633
2005 Hubbard GP, Wolffram S, Lovegrove JA, Gibbins JM. Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humans. Journal of Thrombosis and Haemostasis : Jth. 2: 2138-45. PMID 15613018 DOI: 10.1111/j.1538-7836.2004.01067.x  0.684
2005 Jordan PA, Stevens JM, Hubbard GP, Barrett NE, Sage T, Authi KS, Gibbins JM. A role for the thiol isomerase protein ERP5 in platelet function. Blood. 105: 1500-7. PMID 15466936 DOI: 10.1182/blood-2004-02-0608  0.716
2004 Gibbins JM. Study of tyrosine kinases and protein tyrosine phosphorylation. Methods in Molecular Biology (Clifton, N.J.). 273: 153-68. PMID 15308800 DOI: 10.1385/1-59259-783-1:153  0.494
2004 Gibbins JM. Techniques for analysis of proteins by SDS-polyacrylamide gel electrophoresis and Western blotting. Methods in Molecular Biology (Clifton, N.J.). 273: 139-52. PMID 15308799 DOI: 10.1385/1-59259-783-1:139  0.471
2004 Stevens JM, Jordan PA, Sage T, Gibbins JM. The regulation of integrin-linked kinase in human platelets: evidence for involvement in the regulation of integrin alpha 2 beta 1. Journal of Thrombosis and Haemostasis : Jth. 2: 1443-52. PMID 15304053 DOI: 10.1111/j.1538-7836.2004.00870.x  0.569
2004 Jones ML, Craik JD, Gibbins JM, Poole AW. Regulation of SHP-1 tyrosine phosphatase in human platelets by serine phosphorylation at its C terminus. The Journal of Biological Chemistry. 279: 40475-83. PMID 15269224 DOI: 10.1074/jbc.M402970200  0.567
2004 Gibbins JM. Platelet adhesion signalling and the regulation of thrombus formation. Journal of Cell Science. 117: 3415-25. PMID 15252124 DOI: 10.1242/jcs.01325  0.675
2004 Coffey MJ, Jarvis GE, Gibbins JM, Coles B, Barrett NE, Wylie OR, O'Donnell VB. Platelet 12-lipoxygenase activation via glycoprotein VI: involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis. Circulation Research. 94: 1598-605. PMID 15142951 DOI: 10.1161/01.RES.0000132281.78948.65  0.603
2004 Graham GJ, Stevens JM, Page NM, Grant AD, Brain SD, Lowry PJ, Gibbins JM. Tachykinins regulate the function of platelets Blood. 104: 1058-1065. PMID 15130944 DOI: 10.1182/blood-2003-11-3979  0.664
2004 Batuwangala T, Leduc M, Gibbins JM, Bon C, Jones EY. Structure of the snake-venom toxin convulxin. Acta Crystallographica. Section D, Biological Crystallography. 60: 46-53. PMID 14684891 DOI: 10.1107/s0907444903021620  0.599
2004 Hubbard GP, Wolffram S, Lovegrove JA, Gibbins JM. The role of polyphenolic compounds in the diet as inhibitors of platelet function. The Proceedings of the Nutrition Society. 62: 469-78. PMID 14506895 DOI: 10.1079/PNS2003253  0.706
2003 Barry FA, Graham GJ, Fry MJ, Gibbins JM. Regulation of glycogen synthase kinase 3 in human platelets: a possible role in platelet function? Febs Letters. 553: 173-8. PMID 14550568 DOI: 10.1016/S0014-5793(03)01015-9  0.709
2003 Hubbard GP, Stevens JM, Cicmil M, Sage T, Jordan PA, Williams CM, Lovegrove JA, Gibbins JM. Quercetin inhibits collagen-stimulated platelet activation through inhibition of multiple components of the glycoprotein VI signaling pathway. Journal of Thrombosis and Haemostasis : Jth. 1: 1079-88. PMID 12871380 DOI: 10.1046/j.1538-7836.2003.00212.x  0.707
2003 Polanowska-Grabowska R, Gibbins JM, Gear AR. Platelet adhesion to collagen and collagen-related peptide under flow: roles of the [alpha]2[beta]1 integrin, GPVI, and Src tyrosine kinases. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1934-40. PMID 12869350 DOI: 10.1161/01.ATV.0000086937.46974.70  0.642
2002 Gibbins JM. The negative regulation of platelet function: extending the role of the ITIM. Trends in Cardiovascular Medicine. 12: 213-9. PMID 12161075 DOI: 10.1016/s1050-1738(02)00164-0  0.705
2002 Barry FA, Gibbins JM. Protein kinase B is regulated in platelets by the collagen receptor glycoprotein VI. The Journal of Biological Chemistry. 277: 12874-8. PMID 11825911 DOI: 10.1074/jbc.M200482200  0.685
2002 Cicmil M, Thomas JM, Leduc M, Bon C, Gibbins JM. Platelet endothelial cell adhesion molecule-1 signaling inhibits the activation of human platelets. Blood. 99: 137-44. PMID 11756163  0.726
2000 Cicmil M, Thomas JM, Sage T, Barry FA, Leduc M, Bon C, Gibbins JM. Collagen, convulxin, and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases. The Journal of Biological Chemistry. 275: 27339-47. PMID 10858437 DOI: 10.1074/jbc.M003196200  0.642
2000 Berlanga O, Bobe R, Becker M, Murphy G, Leduc M, Bon C, Barry FA, Gibbins JM, Garcia P, Frampton J, Watson SP. Expression of the collagen receptor glycoprotein VI during megakaryocyte differentiation. Blood. 96: 2740-2745. DOI: 10.1182/Blood.V96.8.2740.H8002740_2740_2745  0.551
1999 Gibbins JM, Briddon S, Shutes A, van Vugt MJ, van de Winkel JG, Saito T, Watson SP. The p85 subunit of phosphatidylinositol 3-kinase associates with the Fc receptor gamma-chain and linker for activitor of T cells (LAT) in platelets stimulated by collagen and convulxin. The Journal of Biological Chemistry. 273: 34437-43. PMID 9852111 DOI: 10.1074/JBC.273.51.34437  0.599
1999 Melford SK, Bunce CM, Gibbins J, Watson SP, Mountford JC. Collagen or Collagen-related Peptide Cause [Ca2+]i Elevation and Increased Tyrosine Phosphorylation in Human Megakaryocytes Thrombosis and Haemostasis. 82: 1153-1159. DOI: 10.1055/S-0037-1614345  0.649
1998 Watson SP, Gibbins J. Collagen receptor signalling in platelets extending the role of the ITAM Immunology Today. 19: 260-264. PMID 9639990 DOI: 10.1016/S0167-5699(98)01267-5  0.681
1997 Gibbins JM, Okuma M, Farndale R, Barnes M, Watson SP. Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor γ-chain Febs Letters. 413: 255-259. PMID 9280292 DOI: 10.1016/S0014-5793(97)00926-5  0.597
1997 Poole A, Gibbins JM, Turner M, van Vugt MJ, van de Winkel JG, Saito T, Tybulewicz VL, Watson SP. The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. The Embo Journal. 16: 2333-41. PMID 9171347 DOI: 10.1093/Emboj/16.9.2333  0.637
1997 Gibbins JM, Woods RJ, Lowry PJ. Affinity purification of 61- and 65-kDa rat brain corticotropin-releasing factor receptors and receptor-associated G proteins. The International Journal of Biochemistry & Cell Biology. 28: 1017-29. PMID 8930125 DOI: 10.1016/1357-2725(96)00041-6  0.521
1997 Asselin J, Gibbins JM, Achison M, Lee YH, Morton LF, Farndale RW, Barnes MJ, Watson SP. A Collagen-Like Peptide Stimulates Tyrosine Phosphorylation of syk and Phospholipase Cγ2 in Platelets Independent of the Integrin α2β1 Blood. 89: 1235-1242. DOI: 10.1182/Blood.V89.4.1235  0.674
1997 Gibbins JM, Okuma M, Farndale R, Barnes M, Watson SP. Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor ??-chain Blood Coagulation & Fibrinolysis. 8: 459. DOI: 10.1097/00001721-199710000-00016  0.609
1996 Gibbins J, Asselin J, Farndale R, Barnes M, Law CL, Watson SP. Tyrosine phosphorylation of the Fc receptor γ-chain in collagen- stimulated platelets Journal of Biological Chemistry. 271: 18095-18099. PMID 8663460 DOI: 10.1074/Jbc.271.30.18095  0.657
1996 Woods RJ, David J, Baigent S, Gibbins J, Lowry PJ. Elevated levels of corticotrophin-releasing factor binding protein in the blood of patients suffering from arthritis and septicaemia and the presence of novel ligands in synovial fluid. British Journal of Rheumatology. 35: 120-4. PMID 8612021 DOI: 10.1093/RHEUMATOLOGY/35.2.120  0.484
1996 Robinson A, Gibbins J, Rodriguez-Linares B, Finan P, Wilson L, Kellie S, Findell P, Watson S. Characterization of Grb2-binding proteins in human platelets activated by Fc gamma RIIA cross-linking Blood. 88: 522-530. DOI: 10.1182/BLOOD.V88.2.522.BLOODJOURNAL882522  0.647
1995 Watson S, Asselin J, Gibbins J, Poole A, Robinson A, Yanaga F. Collagen, wheat germ agglutinin and cross-linking of the platelet low affinity Fc receptor induce activation of the tyrosine kinase syk Blood Coagulation & Fibrinolysis. 6: 596. DOI: 10.1097/00001721-199509000-00032  0.645
1994 Woods RJ, Kennedy KM, Gibbins JM, Behan D, Vale W, Lowry PJ. Corticotropin-releasing factor binding protein dimerizes after association with ligand. Endocrinology. 135: 768-73. PMID 8033825 DOI: 10.1210/endo.135.2.8033825  0.52
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