Ralph Kehlenbach - Publications

Affiliations: 
2000 Georg-August-University Göttingen 

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kehlenbach RH, Neumann P, Ficner R, Dickmanns A. Interaction of nucleoporins with nuclear transport receptors: a structural perspective. Biological Chemistry. PMID 37210735 DOI: 10.1515/hsz-2023-0155  0.695
2023 Pörschke M, Rodríguez-González I, Parfentev I, Urlaub H, Kehlenbach RH. Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein. The Journal of Biological Chemistry. 102932. PMID 36690276 DOI: 10.1016/j.jbc.2023.102932  0.416
2021 Lagadec F, Carlon-Andres I, Ragues J, Port S, Wodrich H, Kehlenbach RH. CRM1 promotes capsid disassembly and nuclear envelope translocation of adenovirus independently of its export function. Journal of Virology. JVI0127321. PMID 34757845 DOI: 10.1128/JVI.01273-21  0.728
2021 Baade I, Hutten S, Sternburg EL, Pörschke M, Hofweber M, Dormann D, Kehlenbach RH. The RNA-binding protein FUS is chaperoned and imported into the nucleus by a network of import receptors. The Journal of Biological Chemistry. 296: 100659. PMID 33857479 DOI: 10.1016/j.jbc.2021.100659  0.424
2021 Hamed M, Caspar B, Port SA, Kehlenbach RH. A nuclear export sequence in Nup214 promotes CRM1-dependent targeting of the nucleoporin to the nuclear pore complex. Journal of Cell Science. PMID 33589493 DOI: 10.1242/jcs.258095  0.5
2021 Chizhik AI, Chizhik AM, Ruhlandt D, Pfaff J, Karedla N, Gregor I, Kehlenbach RH, Enderlein J. Dual-Color Metal-Induced Energy Transfer (MIET) Imaging for Three-Dimensional Reconstruction of Nuclear Envelope Architecture. Methods in Molecular Biology (Clifton, N.J.). 2175: 33-45. PMID 32681482 DOI: 10.1007/978-1-0716-0763-3_4  0.337
2020 Carlon-Andres I, Lagadec F, Pied N, Rayne F, Lafon ME, Kehlenbach RH, Wodrich H. Nup358 and Transportin 1 Cooperate in Adenoviral Genome Import. Journal of Virology. 94. PMID 32161167 DOI: 10.1128/JVI.00164-20  0.7
2019 James C, Müller M, Goldberg MW, Lenz C, Urlaub H, Kehlenbach RH. Proteomic mapping by rapamycin-dependent targeting of APEX2 identifies binding partners of VAPB at the inner nuclear membrane. The Journal of Biological Chemistry. PMID 31519755 DOI: 10.1074/jbc.RA118.007283  0.338
2019 Kindermann B, Valkova C, Krämer A, Perner B, Engelmann C, Behrendt L, Kritsch D, Jungnickel B, Kehlenbach RH, Oswald F, Englert C, Kaether C. The nuclear pore proteins Nup88/214 and T-cell acute lymphatic leukemia-associated NUP214 fusion proteins regulate Notch signaling. The Journal of Biological Chemistry. 294: 11741-11750. PMID 31186352 DOI: 10.1074/jbc.RA118.006357  0.335
2019 Blenski M, Kehlenbach RH. Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane. International Journal of Molecular Sciences. 20. PMID 30650545 DOI: 10.3390/ijms20020334  0.328
2019 Baade I, Kehlenbach RH. The cargo spectrum of nuclear transport receptors. Current Opinion in Cell Biology. 58: 1-7. PMID 30530239 DOI: 10.1016/j.ceb.2018.11.004  0.415
2018 Bonnin E, Cabochette P, Filosa A, Jühlen R, Komatsuzaki S, Hezwani M, Dickmanns A, Martinelli V, Vermeersch M, Supply L, Martins N, Pirenne L, Ravenscroft G, Lombard M, Port S, ... ... Kehlenbach RH, et al. Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence. Plos Genetics. 14: e1007845. PMID 30543681 DOI: 10.1371/journal.pgen.1007845  0.6
2018 Komatsu T, Quentin-Froignant C, Carlon-Andres I, Lagadec F, Rayne F, Ragues J, Kehlenbach RH, Zhang W, Ehrhardt A, Bystricky K, Morin R, Lagarde JM, Gallardo F, Wodrich H. labelling of adenovirus DNA identifies chromatin anchoring and biphasic genome replication. Journal of Virology. PMID 29997215 DOI: 10.1128/JVI.00795-18  0.59
2018 Ederle H, Funk C, Abou-Ajram C, Hutten S, Funk EBE, Kehlenbach RH, Bailer SM, Dormann D. Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1. Scientific Reports. 8: 7084. PMID 29728564 DOI: 10.1038/s41598-018-25007-5  0.434
2018 Baade I, Spillner C, Schmitt K, Valerius O, Kehlenbach RH. Extensive Identification and In-depth Validation of Importin 13 Cargoes. Molecular & Cellular Proteomics : McP. 17: 1337-1353. PMID 29666159 DOI: 10.1074/mcp.RA118.000623  0.379
2017 Chizhik AM, Ruhlandt D, Pfaff J, Karedla N, Chizhik AI, Gregor I, Kehlenbach RH, Enderlein J. Three-Dimensional Reconstruction of Nuclear Envelope Architecture Using Dual-Color Metal-Induced Energy Transfer Imaging. Acs Nano. 11: 11839-11846. PMID 28921961 DOI: 10.1021/acsnano.7b04671  0.327
2016 Landry-Voyer AM, Bilodeau S, Bergeron D, Dionne KL, Port SA, Rouleau C, Boisvert FM, Kehlenbach RH, Bachand F. Human PDCD2L is an export substrate of CRM1 that associates with 40S ribosomal subunit precursors. Molecular and Cellular Biology. PMID 27697862 DOI: 10.1128/Mcb.00303-16  0.348
2016 Port SA, Mendes A, Valkova C, Spillner C, Fahrenkrog B, Kaether C, Kehlenbach RH. The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)+ RNA Export. The Journal of Biological Chemistry. 291: 23068-23083. PMID 27613868 DOI: 10.1074/jbc.M116.735340  0.431
2016 Kehlenbach RH, Port SA. Analysis of CRM1-Dependent Nuclear Export in Permeabilized Cells. Methods in Molecular Biology (Clifton, N.J.). 1411: 489-501. PMID 27147061 DOI: 10.1007/978-1-4939-3530-7_30  0.388
2016 Ficner R, Monecke T, Port SA, Weiß MS, Kehlenbach RH, Dickmanns A. Crystal structure of the 239 kDa nuclear export complex CRM1 - RanGTP - Snurportin1 - Nup214 - MBP Acta Crystallographica Section a Foundations and Advances. 72: s30-s30. DOI: 10.1107/S2053273316099526  0.632
2015 Monecke T, Dickmanns A, Weiss MS, Port SA, Kehlenbach RH, Ficner R. Combining dehydration, construct optimization and improved data collection to solve the crystal structure of a CRM1-RanGTP-SPN1-Nup214 quaternary nuclear export complex. Acta Crystallographica. Section F, Structural Biology Communications. 71: 1481-7. PMID 26625290 DOI: 10.1107/S2053230X15021524  0.661
2015 Dickmanns A, Kehlenbach RH, Fahrenkrog B. Nuclear Pore Complexes and Nucleocytoplasmic Transport: From Structure to Function to Disease. International Review of Cell and Molecular Biology. 320: 171-233. PMID 26614874 DOI: 10.1016/bs.ircmb.2015.07.010  0.689
2015 Port SA, Monecke T, Dickmanns A, Spillner C, Hofele R, Urlaub H, Ficner R, Kehlenbach RH. Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export. Cell Reports. 13: 690-702. PMID 26489467 DOI: 10.1016/j.celrep.2015.09.042  0.707
2015 Halder K, Dölker N, Van Q, Gregor I, Dickmanns A, Baade I, Kehlenbach RH, Ficner R, Enderlein J, Grubmüller H, Neumann H. MD simulations and FRET reveal an environment-sensitive conformational plasticity of importin-β. Biophysical Journal. 109: 277-86. PMID 26200863 DOI: 10.1016/J.Bpj.2015.06.014  0.675
2014 Kimura M, Thakar K, Karaca S, Imamoto N, Kehlenbach RH. Novel approaches for the identification of nuclear transport receptor substrates. Methods in Cell Biology. 122: 353-78. PMID 24857738 DOI: 10.1016/B978-0-12-417160-2.00016-3  0.459
2014 Furuta M, Kose S, Kehlenbach RH, Imamoto N. Analysis of nucleocytoplasmic transport in digitonin-permeabilized cells under different cellular conditions Methods in Cell Biology. 122: 331-352. PMID 24857737 DOI: 10.1016/B978-0-12-417160-2.00015-1  0.39
2014 Frohnert C, Hutten S, Wälde S, Nath A, Kehlenbach RH. Importin 7 and Nup358 promote nuclear import of the protein component of human telomerase. Plos One. 9: e88887. PMID 24586428 DOI: 10.1371/journal.pone.0088887  0.483
2013 Snow CJ, Dar A, Dutta A, Kehlenbach RH, Paschal BM. Defective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport. The Journal of Cell Biology. 201: 541-57. PMID 23649804 DOI: 10.1083/Jcb.201212117  0.722
2013 Roloff S, Spillner C, Kehlenbach RH. Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1. The Journal of Biological Chemistry. 288: 3952-63. PMID 23264634 DOI: 10.1074/jbc.M112.433243  0.473
2013 Thakar K, Karaca S, Port SA, Urlaub H, Kehlenbach RH. Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry. Molecular & Cellular Proteomics : McP. 12: 664-78. PMID 23242554 DOI: 10.1074/mcp.M112.024877  0.379
2012 Malik P, Tabarraei A, Kehlenbach RH, Korfali N, Iwasawa R, Graham SV, Schirmer EC. Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathways. The Journal of Biological Chemistry. 287: 12277-92. PMID 22334672 DOI: 10.1074/Jbc.M111.331777  0.706
2012 Waldmann I, Spillner C, Kehlenbach RH. The nucleoporin-like protein NLP1 (hCG1) promotes CRM1-dependent nuclear protein export. Journal of Cell Science. 125: 144-54. PMID 22250199 DOI: 10.1242/jcs.090316  0.539
2012 Wälde S, Thakar K, Hutten S, Spillner C, Nath A, Rothbauer U, Wiemann S, Kehlenbach RH. The nucleoporin Nup358/RanBP2 promotes nuclear import in a cargo- and transport receptor-specific manner. Traffic (Copenhagen, Denmark). 13: 218-33. PMID 21995724 DOI: 10.1111/j.1600-0854.2011.01302.x  0.495
2011 Hamada M, Haeger A, Jeganathan KB, van Ree JH, Malureanu L, Wälde S, Joseph J, Kehlenbach RH, van Deursen JM. Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability. The Journal of Cell Biology. 194: 597-612. PMID 21859863 DOI: 10.1083/Jcb.201102018  0.498
2010 Wälde S, Kehlenbach RH. The Part and the Whole: functions of nucleoporins in nucleocytoplasmic transport. Trends in Cell Biology. 20: 461-9. PMID 20627572 DOI: 10.1016/j.tcb.2010.05.001  0.406
2009 Hutten S, Wälde S, Spillner C, Hauber J, Kehlenbach RH. The nuclear pore component Nup358 promotes transportin-dependent nuclear import. Journal of Cell Science. 122: 1100-10. PMID 19299463 DOI: 10.1242/jcs.040154  0.414
2008 Hutten S, Flotho A, Melchior F, Kehlenbach RH. The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import. Molecular Biology of the Cell. 19: 2300-10. PMID 18305100 DOI: 10.1091/mbc.e07-12-1279  0.698
2007 Waldmann I, Wälde S, Kehlenbach RH. Nuclear import of c-Jun is mediated by multiple transport receptors. The Journal of Biological Chemistry. 282: 27685-92. PMID 17652081 DOI: 10.1074/jbc.M703301200  0.344
2007 Hutten S, Kehlenbach RH. CRM1-mediated nuclear export: to the pore and beyond. Trends in Cell Biology. 17: 193-201. PMID 17317185 DOI: 10.1016/j.tcb.2007.02.003  0.498
2007 Kehlenbach R, Hutten S. The role of cytoplasmic nucleoporins and pore-associated RanGAP in nuclear import and export Gbm Fall Meeting Hamburg 2007. 2007. DOI: 10.1240/SAV_GBM_2007_H_001877  0.358
2006 Hutten S, Kehlenbach RH. Nup214 is required for CRM1-dependent nuclear protein export in vivo. Molecular and Cellular Biology. 26: 6772-85. PMID 16943420 DOI: 10.1128/MCB.00342-06  0.531
2006 Arnold M, Nath A, Hauber J, Kehlenbach RH. Multiple importins function as nuclear transport receptors for the Rev protein of human immunodeficiency virus type 1. The Journal of Biological Chemistry. 281: 20883-20890. PMID 16704975 DOI: 10.1074/jbc.M602189200  0.415
2006 Kehlenbach RH, Paschal BM. Analysis of Nuclear Protein Import and Export in Digitonin-Permeabilized Cells Cell Biology, Four-Volume Set. 2: 267-275. DOI: 10.1016/B978-012164730-8/50108-8  0.652
2003 Kehlenbach RH. In vitro analysis of nuclear mRNA export using molecular beacons for target detection. Nucleic Acids Research. 31: e64. PMID 12771228 DOI: 10.1093/nar/gng063  0.355
2002 Kehlenbach RH, Gerace L. Analysis of nuclear protein import and export in vitro using fluorescent cargoes. Methods in Molecular Biology (Clifton, N.J.). 189: 231-45. PMID 12094590 DOI: 10.1385/1-59259-281-3:231  0.581
2001 Kehlenbach RH, Assheuer R, Kehlenbach A, Becker J, Gerace L. Stimulation of nuclear export and inhibition of nuclear import by a Ran mutant deficient in binding to Ran-binding protein 1. The Journal of Biological Chemistry. 276: 14524-31. PMID 11278834 DOI: 10.1074/Jbc.M011087200  0.65
2000 Guan T, Kehlenbach RH, Schirmer EC, Kehlenbach A, Fan F, Clurman BE, Arnheim N, Gerace L. Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export. Molecular and Cellular Biology. 20: 5619-30. PMID 10891499 DOI: 10.1128/Mcb.20.15.5619-5630.2000  0.741
2000 Kehlenbach RH, Gerace L. Phosphorylation of the nuclear transport machinery down-regulates nuclear protein import in vitro. The Journal of Biological Chemistry. 275: 17848-56. PMID 10749866 DOI: 10.1074/Jbc.M001455200  0.664
1999 Kehlenbach RH, Dickmanns A, Kehlenbach A, Guan T, Gerace L. A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export. The Journal of Cell Biology. 145: 645-57. PMID 10330396 DOI: 10.1083/Jcb.145.4.645  0.757
1998 Kehlenbach RH, Dickmanns A, Gerace L. Nucleocytoplasmic shuttling factors including Ran and CRM1 mediate nuclear export of NFAT In vitro. The Journal of Cell Biology. 141: 863-74. PMID 9585406 DOI: 10.1083/Jcb.141.4.863  0.73
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