Michael J. Difilippantonio, Ph.D. - Publications

Affiliations: 
1998- National Cancer Institute, Rockville, MD, United States 
Area:
Cancer, Molecular Cytogenetics

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Patkar S, Heselmeyer-Haddad K, Auslander N, Hirsch D, Camps J, Bronder D, Brown M, Chen WD, Lokanga R, Wangsa D, Wangsa D, Hu Y, Lischka A, Braun R, Emons G, ... ... Difilippantonio MJ, et al. Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies. Genome Medicine. 13: 93. PMID 34034815 DOI: 10.1186/s13073-021-00905-y  0.96
2017 McNamara G, Difilippantonio M, Ried T, Bieber FR. Microscopy and Image Analysis. Current Protocols in Human Genetics. 94: 4.4.1-4.4.89. PMID 28696557 DOI: 10.1002/cphg.42  0.96
2015 Grade M, Difilippantonio MJ, Camps J. Patterns of chromosomal aberrations in solid tumors Recent Results in Cancer Research. 200: 115-142. PMID 26376875 DOI: 10.1007/978-3-319-20291-4_6  0.96
2013 Padilla-Nash HM, McNeil NE, Yi M, Nguyen QT, Hu Y, Wangsa D, Mack DL, Hummon AB, Case C, Cardin E, Stephens R, Difilippantonio MJ, Ried T. Aneuploidy, oncogene amplification and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells. Carcinogenesis. 34: 1929-39. PMID 23619298 DOI: 10.1093/Carcin/Bgt138  0.96
2013 Camps J, Pitt JJ, Emons G, Hummon AB, Case CM, Grade M, Jones TL, Nguyen QT, Ghadimi BM, Beissbarth T, Difilippantonio MJ, Caplen NJ, Ried T. Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer. Cancer Research. 73: 2003-13. PMID 23319804 DOI: 10.1158/0008-5472.CAN-12-3159  0.96
2012 Gaedcke J, Grade M, Camps J, Søkilde R, Kaczkowski B, Schetter AJ, Difilippantonio MJ, Harris CC, Ghadimi BM, Møller S, Beissbarth T, Ried T, Litman T. The rectal cancer microRNAome--microRNA expression in rectal cancer and matched normal mucosa. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4919-30. PMID 22850566 DOI: 10.1158/1078-0432.Ccr-12-0016  0.96
2012 Ried T, Hu Y, Difilippantonio MJ, Ghadimi BM, Grade M, Camps J. The consequences of chromosomal aneuploidy on the transcriptome of cancer cells. Biochimica Et Biophysica Acta. 1819: 784-93. PMID 22426433 DOI: 10.1016/J.Bbagrm.2012.02.020  0.96
2012 Hummon AB, Pitt JJ, Camps J, Emons G, Skube SB, Huppi K, Jones TL, Beissbarth T, Kramer F, Grade M, Difilippantonio MJ, Ried T, Caplen NJ. Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells. Molecular Cancer. 11: 1. PMID 22216762 DOI: 10.1186/1476-4598-11-1  0.96
2011 Derfoul A, Juan AH, Difilippantonio MJ, Palanisamy N, Ried T, Sartorelli V. Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase. Carcinogenesis. 32: 1607-14. PMID 21828058 DOI: 10.1093/carcin/bgr184  0.96
2011 Gemoll T, Roblick UJ, Szymczak S, Braunschweig T, Becker S, Igl BW, Bruch HP, Ziegler A, Hellman U, Difilippantonio MJ, Ried T, Jörnvall H, Auer G, Habermann JK. HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers. Cellular and Molecular Life Sciences : Cmls. 68: 3261-74. PMID 21290163 DOI: 10.1007/S00018-011-0628-3  0.96
2011 Grade M, Hummon AB, Camps J, Emons G, Spitzner M, Gaedcke J, Hoermann P, Ebner R, Becker H, Difilippantonio MJ, Ghadimi BM, Beissbarth T, Caplen NJ, Ried T. A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets. International Journal of Cancer. Journal International Du Cancer. 128: 1069-79. PMID 20473941 DOI: 10.1002/Ijc.25453  0.96
2010 Knutsen T, Padilla-Nash HM, Wangsa D, Barenboim-Stapleton L, Camps J, McNeil N, Difilippantonio MJ, Ried T. Definitive molecular cytogenetic characterization of 15 colorectal cancer cell lines. Genes, Chromosomes & Cancer. 49: 204-23. PMID 19927377 DOI: 10.1002/Gcc.20730  0.96
2009 Gertz EM, Sengupta K, Difilippantonio MJ, Ried T, Schäffer AA. Evaluating annotations of an Agilent expression chip suggests that many features cannot be interpreted. Bmc Genomics. 10: 566. PMID 19948035 DOI: 10.1186/1471-2164-10-566  0.96
2009 Difilippantonio MJ, Ghadimi BM, Howard T, Camps J, Nguyen QT, Ferris DK, Sackett DL, Ried T. Nucleation capacity and presence of centrioles define a distinct category of centrosome abnormalities that induces multipolar mitoses in cancer cells. Environmental and Molecular Mutagenesis. 50: 672-96. PMID 19768832 DOI: 10.1002/Em.20532  0.96
2009 Camps J, Nguyen QT, Padilla-Nash HM, Knutsen T, McNeil NE, Wangsa D, Hummon AB, Grade M, Ried T, Difilippantonio MJ. Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer. Genes, Chromosomes & Cancer. 48: 1002-17. PMID 19691111 DOI: 10.1002/Gcc.20699  0.96
2009 Grade M, Gaedcke J, Wangsa D, Varma S, Beckmann J, Liersch T, Hess C, Becker H, Difilippantonio MJ, Ried T, Ghadimi BM. Chromosomal copy number changes of locally advanced rectal cancers treated with preoperative chemoradiotherapy. Cancer Genetics and Cytogenetics. 193: 19-28. PMID 19602460 DOI: 10.1016/j.cancergencyto.2009.03.016  0.96
2009 Callén E, Bunting S, Huang CY, Difilippantonio MJ, Wong N, Khor B, Mahowald G, Kruhlak MJ, Ried T, Sleckman BP, Nussenzweig A. Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG. Cell Cycle (Georgetown, Tex.). 8: 2408-12. PMID 19556863 DOI: 10.4161/Cc.8.15.9085  0.96
2009 Liersch T, Grade M, Gaedcke J, Varma S, Difilippantonio MJ, Langer C, Hess CF, Becker H, Ried T, Ghadimi BM. Preoperative chemoradiotherapy in locally advanced rectal cancer: correlation of a gene expression-based response signature with recurrence. Cancer Genetics and Cytogenetics. 190: 57-65. PMID 19380020 DOI: 10.1016/j.cancergencyto.2008.11.011  0.96
2008 Sengupta K, Camps J, Mathews P, Barenboim-Stapleton L, Nguyen QT, Difilippantonio MJ, Ried T. Position of human chromosomes is conserved in mouse nuclei indicating a species-independent mechanism for maintaining genome organization. Chromosoma. 117: 499-509. PMID 18563425 DOI: 10.1007/s00412-008-0171-7  0.96
2008 Camps J, Grade M, Nguyen QT, Hörmann P, Becker S, Hummon AB, Rodriguez V, Chandrasekharappa S, Chen Y, Difilippantonio MJ, Becker H, Ghadimi BM, Ried T. Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome. Cancer Research. 68: 1284-95. PMID 18316590 DOI: 10.1158/0008-5472.Can-07-2864  0.96
2008 Xu M, Yu Q, Subrahmanyam R, Difilippantonio MJ, Ried T, Sen JM. Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo. Molecular and Cellular Biology. 28: 1713-23. PMID 18160717 DOI: 10.1128/Mcb.01360-07  0.96
2007 Hummon AB, Lim SR, Difilippantonio MJ, Ried T. Isolation and solubilization of proteins after TRIzol extraction of RNA and DNA from patient material following prolonged storage. Biotechniques. 42: 467-70, 472. PMID 17489233 DOI: 10.2144/000112401  0.96
2007 Difilippantonio S, Celeste A, Kruhlak MJ, Lee Y, Difilippantonio MJ, Feigenbaum L, Jackson SP, McKinnon PJ, Nussenzweig A. Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis. The Journal of Experimental Medicine. 204: 1003-11. PMID 17485521 DOI: 10.1084/Jem.20070319  0.64
2007 Xiao C, Sharp JA, Kawahara M, Davalos AR, Difilippantonio MJ, Hu Y, Li W, Cao L, Buetow K, Ried T, Chadwick BP, Deng CX, Panning B. The XIST noncoding RNA functions independently of BRCA1 in X inactivation. Cell. 128: 977-89. PMID 17350580 DOI: 10.1016/J.Cell.2007.01.034  0.96
2007 Sengupta K, Upender MB, Barenboim-Stapleton L, Nguyen QT, Wincovitch SM, Garfield SH, Difilippantonio MJ, Ried T. Artificially introduced aneuploid chromosomes assume a conserved position in colon cancer cells. Plos One. 2: e199. PMID 17332847 DOI: 10.1371/journal.pone.0000199  0.96
2007 Grade M, Hörmann P, Becker S, Hummon AB, Wangsa D, Varma S, Simon R, Liersch T, Becker H, Difilippantonio MJ, Ghadimi BM, Ried T. Gene expression profiling reveals a massive, aneuploidy-dependent transcriptional deregulation and distinct differences between lymph node-negative and lymph node-positive colon carcinomas. Cancer Research. 67: 41-56. PMID 17210682 DOI: 10.1158/0008-5472.Can-06-1514  0.96
2006 Padilla-Nash HM, Barenboim-Stapleton L, Difilippantonio MJ, Ried T. Spectral karyotyping analysis of human and mouse chromosomes. Nature Protocols. 1: 3129-42. PMID 17406576 DOI: 10.1038/nprot.2006.358  0.96
2006 Pisitkun P, Deane JA, Difilippantonio MJ, Tarasenko T, Satterthwaite AB, Bolland S. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science (New York, N.Y.). 312: 1669-72. PMID 16709748 DOI: 10.1126/Science.1124978  0.96
2006 Grade M, Ghadimi BM, Varma S, Simon R, Wangsa D, Barenboim-Stapleton L, Liersch T, Becker H, Ried T, Difilippantonio MJ. Aneuploidy-dependent massive deregulation of the cellular transcriptome and apparent divergence of the Wnt/beta-catenin signaling pathway in human rectal carcinomas. Cancer Research. 66: 267-82. PMID 16397240 DOI: 10.1158/0008-5472.Can-05-2533  0.96
2005 McNamara G, Difilippantonio MJ, Ried T. Microscopy and image analysis. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 4.4. PMID 18428379 DOI: 10.1002/0471142905.hg0404s46  0.96
2005 Simonson SJ, Difilippantonio MJ, Lambert PF. Two distinct activities contribute to human papillomavirus 16 E6's oncogenic potential. Cancer Research. 65: 8266-73. PMID 16166303 DOI: 10.1158/0008-5472.Can-05-1651  0.96
2005 Desper R, Difilippantonio MJ, Ried T, Schäffer AA. A comprehensive continuous-time model for the appearance of CGH signal due to chromosomal missegregations during mitosis Mathematical Biosciences. 197: 67-87. PMID 16043196 DOI: 10.1016/j.mbs.2005.05.005  0.96
2005 Ghadimi BM, Grade M, Difilippantonio MJ, Varma S, Simon R, Montagna C, Füzesi L, Langer C, Becker H, Liersch T, Ried T. Effectiveness of gene expression profiling for response prediction of rectal adenocarcinomas to preoperative chemoradiotherapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 1826-38. PMID 15774776 DOI: 10.1200/JCO.2005.00.406  0.96
2004 Ried T, Dorritie K, Weaver Z, Wangsa D, Difilippantonio MJ, Montagna C. Molecular cytogenetics of mouse models of breast cancer. Breast Disease. 19: 59-67. PMID 15687698 DOI: 10.3233/Bd-2004-19108  0.96
2004 Upender MB, Habermann JK, McShane LM, Korn EL, Barrett JC, Difilippantonio MJ, Ried T. Chromosome transfer induced aneuploidy results in complex dysregulation of the cellular transcriptome in immortalized and cancer cells Cancer Research. 64: 6941-6949. PMID 15466185 DOI: 10.1158/0008-5472.Can-04-0474  0.96
2004 Dorritie K, Montagna C, Difilippantonio MJ, Ried T. Advanced molecular cytogenetics in human and mouse Expert Review of Molecular Diagnostics. 4: 663-676. PMID 15347260 DOI: 10.1586/14737159.4.5.663  0.96
2004 Schaeffer AJ, Nguyen M, Liem A, Lee D, Montagna C, Lambert PF, Ried T, Difilippantonio MJ. E6 and E7 Oncoproteins Induce Distinct Patterns of Chromosomal Aneuploidy in Skin Tumors from Transgenic Mice Cancer Research. 64: 538-546. PMID 14744767 DOI: 10.1158/0008-5472.Can-03-0124  0.96
2004 Schaeffer AJ, Nguyen M, Liem A, Lee D, Montagna C, Lambert PF, Ried T, Difilippantonio MJ. E6 and E7 Oncoproteins Induce Distinct Patterns of Chromosomal Aneuploidy in Skin Tumors from Transgenic Mice Cancer Research. 64: 538-546. PMID 14744767 DOI: 10.1158/0008-5472.Can-03-0124  0.96
2003 Celeste A, Difilippantonio S, Difilippantonio MJ, Fernandez-Capetillo O, Pilch DR, Sedelnikova OA, Eckhaus M, Ried T, Bonner WM, Nussenzweig A. H2AX haploinsufficiency modifies genomic stability and tumor susceptibility Cell. 114: 371-383. PMID 12914701 DOI: 10.1016/S0092-8674(03)00567-1  0.96
2003 Forgues M, Difilippantonio MJ, Linke SP, Ried T, Nagashima K, Feden J, Valerie K, Fukasawa K, Wang XW. Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles. Molecular and Cellular Biology. 23: 5282-92. PMID 12861014 DOI: 10.1128/Mcb.23.15.5282-5292.2003  0.96
2003 Forgues M, Difilippantonio MJ, Linke SP, Ried T, Nagashima K, Feden J, Valerie K, Fukasawa K, Wang XW. Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles. Molecular and Cellular Biology. 23: 5282-92. PMID 12861014 DOI: 10.1128/Mcb.23.15.5282-5292.2003  0.96
2002 Difilippantonio MJ, Petersen S, Chen HT, Johnson R, Jasin M, Kanaar R, Ried T, Nussenzweig A. Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification Journal of Experimental Medicine. 196: 469-480. PMID 12186839 DOI: 10.1084/Jem.20020851  0.96
2002 Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA, Reina-San-Martin B, Coppola V, Meffre E, Difilippantonio MJ, Redon C, Pilch DR, Olaru A, Eckhaus M, Camerini-Otero RD, et al. Genomic instability in mice lacking histone H2AX. Science (New York, N.Y.). 296: 922-7. PMID 11934988 DOI: 10.1126/Science.1069398  0.96
2001 Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, Wilson PC, Hanitsch L, Celeste A, Muramatsu M, Pilch DR, Redon C, Ried T, Bonner WM, Honjo T, Nussenzweig MC, et al. AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching Nature. 414: 660-665. PMID 11740565 DOI: 10.1038/414660A  0.96
2001 Davodeau F, Difilippantonio M, Roldan E, Malissen M, Casanova JL, Couedel C, Morcet JF, Merkenschlager M, Nussenzweig A, Bonneville M, Malissen B. The tight interallelic positional coincidence that distinguishes T-cell receptor Jalpha usage does not result from homologous chromosomal pairing during ValphaJalpha rearrangement. The Embo Journal. 20: 4717-29. PMID 11532936 DOI: 10.1093/Emboj/20.17.4717  0.96
2000 Chen HT, Bhandoola A, Difilippantonio MJ, Zhu J, Brown MJ, Tai X, Rogakou EP, Brotz TM, Bonner WM, Ried T, Nussenzweig A. Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX. Science (New York, N.Y.). 290: 1962-5. PMID 11110662 DOI: 10.1126/Science.290.5498.1962  0.96
2000 Ghadimi BM, Sackett DL, Difilippantonio MJ, Schröck E, Neumann T, Jauho A, Auer G, Ried T. Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations Genes Chromosomes and Cancer. 27: 183-190. PMID 10612807 DOI: 10.1002/(SICI)1098-2264(200002)27:2<183::AID-GCC10>3.0.CO;2-P  0.96
2000 Ghadimi BM, Sackett DL, Difilippantonio MJ, Schröck E, Neumann T, Jauho A, Auer G, Ried T. Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations Genes Chromosomes and Cancer. 27: 183-190. PMID 10612807 DOI: 10.1002/(SICI)1098-2264(200002)27:2<183::AID-GCC10>3.0.CO;2-P  0.96
1997 McMahan CJ, Difilippantonio MJ, Rao N, Spanopoulou E, Schatz DG. A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity. Molecular and Cellular Biology. 17: 4544-52. PMID 9234712 DOI: 10.1128/Mcb.17.8.4544  0.96
1996 Difilippantonio MJ, McMahan CJ, Eastman QM, Spanopoulou E, Schatz DG. RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination. Cell. 87: 253-62. PMID 8861909 DOI: 10.1016/S0092-8674(00)81343-4  0.96
1995 Shockett P, Difilippantonio M, Hellman N, Schatz DG. A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 92: 6522-6. PMID 7604026 DOI: 10.1073/Pnas.92.14.6522  0.96
1993 Otsu K, Fujii J, Periasamy M, Difilippantonio M, Uppender M, Ward DC, MacLennan DH. Chromosome mapping of five human cardiac and skeletal muscle sarcoplasmic reticulum protein genes. Genomics. 17: 507-9. PMID 8406504 DOI: 10.1006/Geno.1993.1357  0.96
1993 Lichter JB, Difilippantonio MJ, Pakstis AJ, Goodfellow PJ, Ward DC, Kidd KK. Physical and genetic maps for chromosome 10. Genomics. 16: 320-4. PMID 8314570 DOI: 10.1006/Geno.1993.1192  0.96
1992 Lichter JB, Difilippantonio M, Wu J, Miller D, Ward DC, Goodfellow PJ, Kidd KK. Localization of the gene for MEN 2A. Henry Ford Hospital Medical Journal. 40: 199-204. PMID 1362405  0.96
1991 Doucette-Stamm LA, Riba L, Handelin B, Difilippantonio M, Ward DC, Wasmuth JJ, Gusella JF, Housman DE. Generation and characterization of irradiation hybrids of human chromosome 4. Somatic Cell and Molecular Genetics. 17: 471-80. PMID 1837181 DOI: 10.1007/Bf01233171  0.4
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