Michael J. Difilippantonio, Ph.D. - Related publications

Affiliations: 
1998- National Cancer Institute, Rockville, MD, United States 
Area:
Cancer, Molecular Cytogenetics
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Wu S, Bafna V, Chang HY, Mischel PS. Extrachromosomal DNA: An Emerging Hallmark in Human Cancer. Annual Review of Pathology. PMID 34752712 DOI: 10.1146/annurev-pathmechdis-051821-114223   
2021 Chu X, Wang J. Deciphering the molecular mechanism of the cancer formation by chromosome structural dynamics. Plos Computational Biology. 17: e1009596. PMID 34752443 DOI: 10.1371/journal.pcbi.1009596   
2021 Yu SH, Cai JH, Chen DL, Liao SH, Lin YZ, Chung YT, Tsai JJP, Wang CCN. LASSO and Bioinformatics Analysis in the Identification of Key Genes for Prognostic Genes of Gynecologic Cancer. Journal of Personalized Medicine. 11. PMID 34834529 DOI: 10.3390/jpm11111177   
2021 Wen J, Mao X, Cheng Q, Liu Z, Liu F. A pan-cancer analysis revealing the role of TIGIT in tumor microenvironment. Scientific Reports. 11: 22502. PMID 34795387 DOI: 10.1038/s41598-021-01933-9   
2021 Contreras-Trujillo H, Eerdeng J, Akre S, Jiang D, Contreras J, Gala B, Vergel-Rodriguez MC, Lee Y, Jorapur A, Andreasian A, Harton L, Bramlett CS, Nogalska A, Xiao G, Lee JW, et al. Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses. Nature Communications. 12: 6522. PMID 34764253 DOI: 10.1038/s41467-021-26771-1   
2021 Hao N, Zhou Y, Li Y, Zhang H, Wang B, Liu X, Ren Y, He J, Zhou C, Tang X. Clinical Value and Potential Mechanisms of Oxysterol-Binding Protein Like 3 (OSBPL3) in Human Tumors. Frontiers in Molecular Biosciences. 8: 739978. PMID 34738015 DOI: 10.3389/fmolb.2021.739978   
2021 Zboril E, Yoo H, Chen L, Liu Z. Dynamic Interactions of Transcription Factors and Enhancer Reprogramming in Cancer Progression. Frontiers in Oncology. 11: 753051. PMID 34616687 DOI: 10.3389/fonc.2021.753051   
2021 Yan Y, Liang Q, Xu Z, Yi Q. Integrative bioinformatics and experimental analysis revealed down-regulated CDC42EP3 as a novel prognostic target for ovarian cancer and its roles in immune infiltration. Peerj. 9: e12171. PMID 34616622 DOI: 10.7717/peerj.12171   
2021 Guo Z, Liang E, Li W, Jiang L, Zhi F. Essential meiotic structure-specific endonuclease1 () promotes malignant features in gastric cancer cells via the Akt/GSK3B/CCND1 pathway. Bioengineered. PMID 34719326 DOI: 10.1080/21655979.2021.1999371   
2021 Bajrai LH, Sohrab SS, Mobashir M, Kamal MA, Rizvi MA, Azhar EI. Understanding the role of potential pathways and its components including hypoxia and immune system in case of oral cancer. Scientific Reports. 11: 19576. PMID 34599215 DOI: 10.1038/s41598-021-98031-7   
2021 Wu Y, Chen Q, Zhang Q, Li M, Li H, Jia L, Huang Y, Zhang J. Analysis of whole-exome data of cfDNA and the tumor tissue of non-small cell lung cancer. Annals of Translational Medicine. 9: 1453. PMID 34734005 DOI: 10.21037/atm-21-4117   
2021 Farhana A, Koh AE, Kothandan S, Alsrhani A, Mok PL, Subbiah SK. Treatment of HT29 Human Colorectal Cancer Cell Line with Nanocarrier-Encapsulated Camptothecin Reveals Histone Modifier Genes in the Signaling Pathway as Important Molecular Cues for Colon Cancer Targeting. International Journal of Molecular Sciences. 22. PMID 34830168 DOI: 10.3390/ijms222212286   
2021 He Y, Wu Y, Liu Z, Li B, Jiang N, Xu P, Xu A. Identification of Signature Genes Associated With Invasiveness and the Construction of a Prognostic Model That Predicts the Overall Survival of Bladder Cancer. Frontiers in Genetics. 12: 694777. PMID 34589112 DOI: 10.3389/fgene.2021.694777   
2021 Bezrookove V, Patino JM, Nosrati M, Desprez PY, McAllister S, Soroceanu L, Baron A, Osorio R, Kashani-Sabet M, Dar AA. Niraparib Suppresses Cholangiocarcinoma Tumor Growth by Inducing Oxidative and Replication Stress. Cancers. 13. PMID 34503215 DOI: 10.3390/cancers13174405   
2021 Kaushik Tiwari M, Colon-Rios DA, Tumu HCR, Liu Y, Quijano E, Krysztofiak A, Chan C, Song E, Braddock DT, Suh HW, Saltzman WM, Rogers FA. Direct targeting of amplified gene loci for proapoptotic anticancer therapy. Nature Biotechnology. PMID 34711990 DOI: 10.1038/s41587-021-01057-5   
2021 Sanghi A, Gruber JJ, Metwally A, Jiang L, Reynolds W, Sunwoo J, Orloff L, Chang HY, Kasowski M, Snyder MP. Chromatin accessibility associates with protein-RNA correlation in human cancer. Nature Communications. 12: 5732. PMID 34593797 DOI: 10.1038/s41467-021-25872-1   
2021 Lin JC, Liu TP, Andriani V, Athoillah M, Wang CY, Yang PM. Bioinformatics Analysis Identifies Precision Treatment with Paclitaxel for Hepatocellular Carcinoma Patients Harboring Mutant or Wild-Type Gene. Journal of Personalized Medicine. 11. PMID 34834551 DOI: 10.3390/jpm11111199   
2021 Chen M, Linstra R, Van Vugt MATM. Genomic instability, inflammatory signaling and response to cancer immunotherapy. Biochimica Et Biophysica Acta. Reviews On Cancer. 188661. PMID 34800547 DOI: 10.1016/j.bbcan.2021.188661   
2021 Du H, Tang J, Li X, Wang X, Wu L, Zhang R, Hu P, Yang Y. Siglec-15 Is an Immune Suppressor and Potential Target for Immunotherapy in the Pre-Metastatic Lymph Node of Colorectal Cancer. Frontiers in Cell and Developmental Biology. 9: 691937. PMID 34722496 DOI: 10.3389/fcell.2021.691937   
2021 Guo ZS, Qu Z. PDLIM2: Signaling pathways and functions in cancer suppression and host immunity. Biochimica Et Biophysica Acta. Reviews On Cancer. 1876: 188630. PMID 34571051 DOI: 10.1016/j.bbcan.2021.188630   
2021 Shen S, Wang Y, Zhang Y, Dong Z, Xing J. Long Non-coding RNA Small Nucleolar RNA Host Gene 14, a Promising Biomarker and Therapeutic Target in Malignancy. Frontiers in Cell and Developmental Biology. 9: 746714. PMID 34631721 DOI: 10.3389/fcell.2021.746714   
2021 Wu H, Zhou Y, Wu H, Xu L, Yan Y, Tong X, Yan H. CENPN Acts as a Novel Biomarker that Correlates With the Malignant Phenotypes of Glioma Cells. Frontiers in Genetics. 12: 732376. PMID 34646306 DOI: 10.3389/fgene.2021.732376   
2021 Zhao X, Li J, Liu Z, Powers S. Combinatorial CRISPR/Cas9 Screening Reveals Epistatic Networks of Interacting Tumor Suppressor Genes and Therapeutic Targets in Human Breast Cancer. Cancer Research. PMID 34561273 DOI: 10.1158/0008-5472.CAN-21-2555   
2021 Gorji-Bahri G, Moradtabrizi N, Hashemi A. Uncovering the stability status of the reputed reference genes in breast and hepatic cancer cell lines. Plos One. 16: e0259669. PMID 34752497 DOI: 10.1371/journal.pone.0259669   
2021 Xu Z, Hu K, Bailey P, Springfeld C, Roth S, Kurilov R, Brors B, Gress T, Buchholz M, An J, Wei K, Peccerella T, Büchler MW, Hackert T, Neoptolemos JP. Clinical Impact of Molecular Subtyping of Pancreatic Cancer. Frontiers in Cell and Developmental Biology. 9: 743908. PMID 34805152 DOI: 10.3389/fcell.2021.743908   
2021 Zhang S, Wan J, Chen M, Cai D, Xu J, Chen Q. Tumor-Infiltrating CD8+ T Cells Driven by the Immune Checkpoint-Associated Gene IDO1 Are Associated With Cervical Cancer Prognosis. Frontiers in Oncology. 11: 720447. PMID 34778035 DOI: 10.3389/fonc.2021.720447   
2021 Boldrini L, Faviana P, Galli L, Paolieri F, Erba PA, Bardi M. Multi-Dimensional Scaling Analysis of Key Regulatory Genes in Prostate Cancer Using the TCGA Database. Genes. 12. PMID 34573332 DOI: 10.3390/genes12091350   
2021 Bagheri-Yarmand R, Busaidy NL, McBeath E, Danysh BP, Evans KW, Moss TJ, Akcakanat A, Ng PKS, Knippler CM, Golden JA, Williams MD, Multani AS, Cabanillas ME, Shaw KR, Meric-Bernstam F, et al. Alterations Induce Acquired Dabrafenib Resistance in Association with Anaplastic Transformation in a Papillary Thyroid Cancer Patient. Cancers. 13. PMID 34638434 DOI: 10.3390/cancers13194950   
2021 Garrido MA, Perea F, Vilchez JR, Rodríguez T, Anderson P, Garrido F, Ruiz-Cabello F, Aptsiauri N. Copy Neutral LOH Affecting the Entire Chromosome 6 Is a Frequent Mechanism of Class I Alterations in Cancer. Cancers. 13. PMID 34680201 DOI: 10.3390/cancers13205046   
2021 Jin L, Zheng D, Chen D, Xia E, Guan Y, Wen J, Bhandari A, Wang O. SYT12 is a novel oncogene that promotes thyroid carcinoma progression and metastasis. Journal of Cancer. 12: 6851-6860. PMID 34659573 DOI: 10.7150/jca.62555   
2021 Chen L, Qian J, You Q, Ma J. LIM domain-containing 2 (LIMD2) promotes the progress of ovarian cancer via the focal adhesion signaling pathway. Bioengineered. PMID 34724866 DOI: 10.1080/21655979.2021.2000732   
2021 Cheng L, Creasy T, Pilataxi F, Greenlees L, Vence L, Sridhar S, Streicher K. Effects of combination treatment with durvalumab plus tremelimumab on the tumor microenvironment in non-small-cell lung carcinoma. Cancer Immunology, Immunotherapy : Cii. PMID 34623465 DOI: 10.1007/s00262-021-03065-5   
2021 Shi J, Bao M, Wang W, Wu X, Li Y, Zhao C, Liu W. Integrated Profiling Identifies as a Potential Prognostic and Immunotherapy Relevant Biomarker in Colorectal Cancer. Frontiers in Immunology. 12: 722807. PMID 34646265 DOI: 10.3389/fimmu.2021.722807   
2021 Feng C, Xu Y, Liu Y, Zhu L, Wang L, Cui X, Lu J, Zhang Y, Zhou L, Chen M, Zhang Z, Li P. Gene Expression Subtyping Reveals Immune alterations:TCGA Database for Prognosis in Ovarian Serous Cystadenocarcinoma. Frontiers in Molecular Biosciences. 8: 619027. PMID 34631788 DOI: 10.3389/fmolb.2021.619027   
2021 Shao W, Ding Q, Guo Y, Xing J, Huo Z, Wang Z, Xu Q, Guo Y. A Pan-Cancer Landscape of HOX-Related lncRNAs and Their Association With Prognosis and Tumor Microenvironment. Frontiers in Molecular Biosciences. 8: 767856. PMID 34805277 DOI: 10.3389/fmolb.2021.767856   
2021 Zakir U, Siddiqui NN, Naqvi FU, Khan R. Aberrant STAT1 methylation as a non-invasive biomarker in blood of HCV induced hepatocellular carcinoma. Cancer Biomarkers : Section a of Disease Markers. PMID 34657877 DOI: 10.3233/CBM-210216   
2021 Li X, Liang W, Zhao H, Jin Z, Shi G, Xie W, Wang H, Wu X. Immune Cell Infiltration Landscape of Ovarian Cancer to Identify Prognosis and Immunotherapy-Related Genes to Aid Immunotherapy. Frontiers in Cell and Developmental Biology. 9: 749157. PMID 34805159 DOI: 10.3389/fcell.2021.749157   
2021 Yang Y, Zhang X, Lei Y, Chang G, Zou Y, Yu S, Wu H, Rong H, Lei Z, Xu C. The effects of H22 tumor on the quality of oocytes and the development of early embryos from host mice: A single-cell RNA sequencing approach. Theriogenology. 179: 45-59. PMID 34826707 DOI: 10.1016/j.theriogenology.2021.11.006   
2021 Jiang J, Yuan J, Hu Z, Xu M, Zhang Y, Long M, Fan Y, Montone K, Tanyi JL, Tavana O, Chan HM, Zhang L, Hu X. Systematic pan-cancer characterization of nuclear receptors identifies potential cancer biomarkers and therapeutic targets. Cancer Research. PMID 34750098 DOI: 10.1158/0008-5472.CAN-20-3458   
2021 Pan W, Wang K, Li J, Li H, Cai Y, Zhang M, Wang A, Wu Y, Gao W, Weng W. Restoring Exhibits Therapeutic Potential for Ameliorating Malignant Progression and 5-Fluorouracil Resistance in Colorectal Cancer. Frontiers in Oncology. 11: 771528. PMID 34790580 DOI: 10.3389/fonc.2021.771528   
2021 Chen X, Song J, Wang X, Sun D, Liu Y, Jiang Y. LncRNA LINC00460: Function and mechanism in human cancer. Thoracic Cancer. PMID 34821482 DOI: 10.1111/1759-7714.14238   
2021 Rivas MA, Durmaz C, Kloetgen A, Chin CR, Chen Z, Bhinder B, Koren A, Viny AD, Scharer CD, Boss JM, Elemento O, Mason CE, Melnick AM. Cohesin Core Complex Gene Dosage Contributes to Germinal Center Derived Lymphoma Phenotypes and Outcomes. Frontiers in Immunology. 12: 688493. PMID 34621263 DOI: 10.3389/fimmu.2021.688493   
2021 Huang J, Wang Y, Liu J, Chu M, Wang Y. TFDP3 as E2F Unique Partner, Has Crucial Roles in Cancer Cells and Testis. Frontiers in Oncology. 11: 742462. PMID 34745961 DOI: 10.3389/fonc.2021.742462   
2021 Spillane CD, Cooke NM, Ward MP, Kenny D, Blackshields G, Kelly T, Bates M, Huang Y, Martin C, Skehan S, Canney A, Gallagher M, Smyth P, Brady N, Clarke A, et al. The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon. Translational Oncology. 14: 101229. PMID 34592589 DOI: 10.1016/j.tranon.2021.101229   
2021 Liu H, Xu R, Gao C, Zhu T, Liu L, Yang Y, Zeng H, Huang Y, Wang H. Metabolic Molecule PLA2G2D Is a Potential Prognostic Biomarker Correlating With Immune Cell Infiltration and the Expression of Immune Checkpoint Genes in Cervical Squamous Cell Carcinoma. Frontiers in Oncology. 11: 755668. PMID 34733790 DOI: 10.3389/fonc.2021.755668   
2021 Sweat Y, Ries RJ, Sweat M, Su D, Shao F, Eliason S, Amendt BA. acts as a tumor suppressor by negatively regulating the cluster. Molecular Therapy. Nucleic Acids. 26: 1148-1158. PMID 34853714 DOI: 10.1016/j.omtn.2021.10.021   
2021 Zhao Z, Wan J, Guo M, Wang Y, Yang Z, Zhou F, Li Z, Ming L. Expression and prognostic significance of m6A-related genes in TP53-mutant non-small-cell lung cancer. Journal of Clinical Laboratory Analysis. e24118. PMID 34812534 DOI: 10.1002/jcla.24118   
2021 Hu J, Xu J, Feng X, Li Y, Hua F, Xu G. Differential Expression of the Gene in Pan-Cancer and Its Related Mechanism. Frontiers in Cell and Developmental Biology. 9: 700661. PMID 34631699 DOI: 10.3389/fcell.2021.700661   
2021 Andersson A, Larsson L, Stenbeck L, Salmén F, Ehinger A, Wu SZ, Al-Eryani G, Roden D, Swarbrick A, Borg Å, Frisén J, Engblom C, Lundeberg J. Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions. Nature Communications. 12: 6012. PMID 34650042 DOI: 10.1038/s41467-021-26271-2   
2021 Zhong A, Chen T, Zhou T, Zhang Z, Shi M. TPD52L2 Is a Prognostic Biomarker and Correlated With Immune Infiltration in Lung Adenocarcinoma. Frontiers in Pharmacology. 12: 728420. PMID 34744715 DOI: 10.3389/fphar.2021.728420