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Joseph B. O'Brien - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Dwyer TS, O'Brien JB, Ptak CP, LaVigne JE, Flaherty DP, Watts VJ, Roman DL. Protein-protein interaction-based high throughput screening for adenylyl cyclase 1 inhibitors: Design, implementation, and discovery of a novel chemotype. Frontiers in Pharmacology. 13: 977742. PMID 36147328 DOI: 10.3389/fphar.2022.977742  0.671
2021 Cagle BS, Sturgeon ML, O'Brien JB, Wilkinson JC, Cornell RA, Roman DL, Doorn JA. Stable expression of the human dopamine transporter in N27 cells as an in vitro model for dopamine cell trafficking and metabolism. Toxicology in Vitro : An International Journal Published in Association With Bibra. 76: 105210. PMID 34252731 DOI: 10.1016/j.tiv.2021.105210  0.5
2021 O'Brien JB, Roman DL. Novel treatments for chronic pain: moving beyond opioids. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 33727192 DOI: 10.1016/j.trsl.2021.03.008  0.529
2021 Hayes MP, O'Brien J, Fowler CA, Yu L, Roman DL, Crawford R, Doorn JA. Fragment-based nuclear magnetic resonance screen against a Regulator of G Protein Signaling identifies a binding "hot spot". Chembiochem : a European Journal of Chemical Biology. PMID 33480159 DOI: 10.1002/cbic.202000740  0.747
2019 O'Brien JB, Wilkinson JC, Roman DL. Regulator of G protein signaling (RGS) proteins as drug targets: Progress and future potentials. The Journal of Biological Chemistry. PMID 31636120 DOI: 10.1074/Jbc.Rev119.007060  0.753
2019 Sieng M, Hayes MP, O'Brien JB, Fowler CA, Houtman JC, Roman DL, Lyon AM. High-resolution structure of RGS17 suggests a role for Ca2+ in promoting the GTPase activating protein activity by RZ subfamily members. The Journal of Biological Chemistry. PMID 30940727 DOI: 10.1074/Jbc.Ra118.006059  0.71
2018 Bodle CR, Schamp JH, O'Brien JB, Hayes MP, Wu M, Doorn JA, Roman DL. Screen Targeting Lung and Prostate Cancer Oncogene Identifies Novel Inhibitors of RGS17 and Problematic Chemical Substructures. Slas Discovery : Advancing Life Sciences R & D. 2472555217752301. PMID 29351497 DOI: 10.1177/2472555217752301  0.665
2017 Bodle CR, Hayes MP, O'Brien JB, Roman DL. "Development of bimolecular luminescence complementation assay for RGS: G protein interactions in cells." Analytical Biochemistry. PMID 28115169 DOI: 10.1016/j.ab.2017.01.013  0.666
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