| Year |
Citation |
Score |
| 2022 |
Morton SB, Finger LD, van der Sluijs R, Mulcrone WD, Hodskinson M, Millington CL, Vanhinsbergh C, Patel KJ, Dickman MJ, Knipscheer P, Grasby JA, Williams DM. Efficient Synthesis of DNA Duplexes Containing Reduced Acetaldehyde Interstrand Cross-Links. Journal of the American Chemical Society. PMID 36584283 DOI: 10.1021/jacs.2c10070 |
0.456 |
|
| 2021 |
Mulderrig L, Garaycoechea JI, Tuong ZK, Millington CL, Dingler FA, Ferdinand JR, Gaul L, Tadross JA, Arends MJ, O'Rahilly S, Crossan GP, Clatworthy MR, Patel KJ. Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response. Nature. 600: 158-163. PMID 34819667 DOI: 10.1038/s41586-021-04133-7 |
0.36 |
|
| 2020 |
Hodskinson MR, Bolner A, Sato K, Kamimae-Lanning AN, Rooijers K, Witte M, Mahesh M, Silhan J, Petek M, Williams DM, Kind J, Chin JW, Patel KJ, Knipscheer P. Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms. Nature. PMID 32132710 DOI: 10.1038/S41586-020-2059-5 |
0.46 |
|
| 2020 |
Alcón P, Shakeel S, Chen ZA, Rappsilber J, Patel KJ, Passmore LA. FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair. Nature Structural & Molecular Biology. PMID 32066963 DOI: 10.1038/S41594-020-0380-1 |
0.485 |
|
| 2019 |
Shakeel S, Rajendra E, Alcón P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, et al. Structure of the Fanconi anaemia monoubiquitin ligase complex. Nature. PMID 31666700 DOI: 10.1038/S41586-019-1703-4 |
0.367 |
|
| 2019 |
Wu RA, Semlow DR, Kamimae-Lanning AN, Kochenova OV, Chistol G, Hodskinson MR, Amunugama R, Sparks JL, Wang M, Deng L, Mimoso CA, Low E, Patel KJ, Walter JC. TRAIP is a master regulator of DNA interstrand crosslink repair. Nature. PMID 30842657 DOI: 10.1038/S41586-019-1002-0 |
0.478 |
|
| 2018 |
Garaycoechea JI, Crossan GP, Langevin F, Mulderrig L, Louzada S, Yang F, Guilbaud G, Park N, Roerink S, Nik-Zainal S, Stratton MR, Patel KJ. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 553: 171-177. PMID 29323295 DOI: 10.1038/nature25154 |
0.371 |
|
| 2017 |
Dingler FA, Patel KJ. Of sizzling steaks and DNA repair. Science (New York, N.Y.). 357: 130-131. PMID 28706026 DOI: 10.1126/science.aan8293 |
0.467 |
|
| 2015 |
Pontel LB, Rosado IV, Burgos-Barragan G, Garaycoechea JI, Yu R, Arends MJ, Chandrasekaran G, Broecker V, Wei W, Liu L, Swenberg JA, Crossan GP, Patel KJ. Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen. Molecular Cell. PMID 26412304 DOI: 10.1016/J.Molcel.2015.08.020 |
0.437 |
|
| 2015 |
Gibbs-Seymour I, Oka Y, Rajendra E, Weinert BT, Passmore LA, Patel KJ, Olsen JV, Choudhary C, Bekker-Jensen S, Mailand N. Ubiquitin-SUMO circuitry controls activated fanconi anemia ID complex dosage in response to DNA damage. Molecular Cell. 57: 150-64. PMID 25557546 DOI: 10.1016/J.Molcel.2014.12.001 |
0.407 |
|
| 2014 |
Rajendra E, Garaycoechea JI, Patel KJ, Passmore LA. Abundance of the Fanconi anaemia core complex is regulated by the RuvBL1 and RuvBL2 AAA+ ATPases. Nucleic Acids Research. 42: 13736-48. PMID 25428364 DOI: 10.1093/nar/gku1230 |
0.45 |
|
| 2014 |
Rajendra E, Oestergaard VH, Langevin F, Wang M, Dornan GL, Patel KJ, Passmore LA. The genetic and biochemical basis of FANCD2 monoubiquitination. Molecular Cell. 54: 858-69. PMID 24905007 DOI: 10.1016/j.molcel.2014.05.001 |
0.421 |
|
| 2014 |
Hodskinson MR, Silhan J, Crossan GP, Garaycoechea JI, Mukherjee S, Johnson CM, Schärer OD, Patel KJ. Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair. Molecular Cell. 54: 472-84. PMID 24726326 DOI: 10.1016/J.Molcel.2014.03.014 |
0.496 |
|
| 2013 |
Sale JE, Patel KJ, Batista FD. Retrospective. Michael Neuberger (1953-2013). Science (New York, N.Y.). 342: 1335. PMID 24337288 DOI: 10.1126/Science.1248808 |
0.496 |
|
| 2012 |
Garaycoechea JI, Crossan GP, Langevin F, Daly M, Arends MJ, Patel KJ. Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function. Nature. 489: 571-5. PMID 22922648 DOI: 10.1038/nature11368 |
0.452 |
|
| 2012 |
Kelsall IR, Langenick J, MacKay C, Patel KJ, Alpi AF. The Fanconi anaemia components UBE2T and FANCM are functionally linked to nucleotide excision repair. Plos One. 7: e36970. PMID 22615860 DOI: 10.1371/journal.pone.0036970 |
0.487 |
|
| 2012 |
Sarkies P, Murat P, Phillips LG, Patel KJ, Balasubramanian S, Sale JE. FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA. Nucleic Acids Research. 40: 1485-98. PMID 22021381 DOI: 10.1093/Nar/Gkr868 |
0.655 |
|
| 2012 |
Crossan GP, Patel KJ. The Fanconi anaemia pathway orchestrates incisions at sites of crosslinked DNA. The Journal of Pathology. 226: 326-37. PMID 21956823 DOI: 10.1002/path.3002 |
0.524 |
|
| 2012 |
Patel KJ. Links Between DNA Damage and Metabolism, Pathways Causing Bone Marrow Failure in Fanconi Anemia, and Therapeutic Implications Blood. 120: SCI-3-SCI-3. DOI: 10.1182/BLOOD.V120.21.SCI-3.SCI-3 |
0.371 |
|
| 2011 |
Rosado IV, Langevin F, Crossan GP, Takata M, Patel KJ. Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway. Nature Structural & Molecular Biology. 18: 1432-4. PMID 22081012 DOI: 10.1038/nsmb.2173 |
0.495 |
|
| 2011 |
Crossan GP, van der Weyden L, Rosado IV, Langevin F, Gaillard PH, McIntyre RE, Gallagher F, Kettunen MI, Lewis DY, Brindle K, Arends MJ, Adams DJ, Patel KJ. Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia. Nature Genetics. 43: 147-52. PMID 21240276 DOI: 10.1038/Ng.752 |
0.474 |
|
| 2010 |
Pace P, Mosedale G, Hodskinson MR, Rosado IV, Sivasubramaniam M, Patel KJ. Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway. Science (New York, N.Y.). 329: 219-23. PMID 20538911 DOI: 10.1126/science.1192277 |
0.519 |
|
| 2009 |
Rosado IV, Niedzwiedz W, Alpi AF, Patel KJ. The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair. Nucleic Acids Research. 37: 4360-70. PMID 19465393 DOI: 10.1093/nar/gkp365 |
0.699 |
|
| 2009 |
Alpi AF, Patel KJ. Monoubiquitylation in the Fanconi anemia DNA damage response pathway. Dna Repair. 8: 430-5. PMID 19264559 DOI: 10.1016/j.dnarep.2009.01.019 |
0.402 |
|
| 2007 |
Oestergaard VH, Langevin F, Kuiken HJ, Pace P, Niedzwiedz W, Simpson LJ, Ohzeki M, Takata M, Sale JE, Patel KJ. Deubiquitination of FANCD2 is required for DNA crosslink repair. Molecular Cell. 28: 798-809. PMID 18082605 DOI: 10.1016/J.Molcel.2007.09.020 |
0.718 |
|
| 2007 |
Patel KJ, Joenje H. Fanconi anemia and DNA replication repair. Dna Repair. 6: 885-90. PMID 17481966 DOI: 10.1016/j.dnarep.2007.02.002 |
0.389 |
|
| 2006 |
Simpson LJ, Ross AL, Szüts D, Alviani CA, Oestergaard VH, Patel KJ, Sale JE. RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40. Embo Reports. 7: 927-32. PMID 16888649 DOI: 10.1038/Sj.Embor.7400777 |
0.638 |
|
| 2005 |
Mosedale G, Niedzwiedz W, Alpi A, Perrina F, Pereira-Leal JB, Johnson M, Langevin F, Pace P, Patel KJ. The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway. Nature Structural & Molecular Biology. 12: 763-71. PMID 16116434 DOI: 10.1038/Nsmb981 |
0.71 |
|
| 2005 |
Niedzwiedz W, Patel KJ. "Dub"bing a tumor suppressor pathway. Cancer Cell. 7: 114-5. PMID 15710323 DOI: 10.1016/j.ccr.2005.01.018 |
0.68 |
|
| 2004 |
Niedzwiedz W, Mosedale G, Johnson M, Ong CY, Pace P, Patel KJ. The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair. Molecular Cell. 15: 607-20. PMID 15327776 DOI: 10.1016/j.molcel.2004.08.009 |
0.727 |
|
| 2003 |
Vandenberg CJ, Gergely F, Ong CY, Pace P, Mallery DL, Hiom K, Patel KJ. BRCA1-independent ubiquitination of FANCD2. Molecular Cell. 12: 247-54. PMID 12887909 |
0.434 |
|
| 2001 |
Joenje H, Patel KJ. The emerging genetic and molecular basis of Fanconi anaemia. Nature Reviews. Genetics. 2: 446-57. PMID 11389461 DOI: 10.1038/35076590 |
0.321 |
|
| 1998 |
Patel KJ, Yu VP, Lee H, Corcoran A, Thistlethwaite FC, Evans MJ, Colledge WH, Friedman LS, Ponder BA, Venkitaraman AR. Involvement of Brca2 in DNA repair. Molecular Cell. 1: 347-57. PMID 9660919 DOI: 10.1016/S1097-2765(00)80035-0 |
0.718 |
|
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