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Joel O Melby, Ph.D. - Publications

Affiliations: 
2009-2015 Chemistry University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
 2015-2020 Chemistry GlaxoSmithKline, Collegeville, PA, United States 
 2021- Data Analysis TetraScience 
Area:
Chemical biology
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12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Melby JO, Li X, Mitchell DA. Correction to "Orchestration of Enzymatic Processing by Thiazole/Oxazole-Modified Microcin Dehydrogenases". Biochemistry. PMID 31855405 DOI: 10.1021/Acs.Biochem.9B01042  0.434
2015 Metelev M, Tietz JI, Melby JO, Blair PM, Zhu L, Livnat I, Severinov K, Mitchell DA. Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso Peptide from an understudied halophilic actinomycete. Chemistry & Biology. 22: 241-50. PMID 25601074 DOI: 10.1016/J.Chembiol.2014.11.017  0.572
2015 Tietz J, Zhu L, Mitchell D, Metelev M, Melby J, Blair P, Livnat I, Severinov K. Solution-state NMR structure of the lasso peptide streptomonomicin Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Mw3/Pdb  0.474
2014 Zhang Q, Ortega M, Shi Y, Wang H, Melby JO, Tang W, Mitchell DA, van der Donk WA. Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS. Proceedings of the National Academy of Sciences of the United States of America. 111: 12031-6. PMID 25092299 DOI: 10.1073/Pnas.1406418111  0.614
2014 Cox CL, Tietz JI, Sokolowski K, Melby JO, Doroghazi JR, Mitchell DA. Nucleophilic 1,4-additions for natural product discovery. Acs Chemical Biology. 9: 2014-22. PMID 24937678 DOI: 10.1021/Cb500324N  0.574
2014 Melby JO, Li X, Mitchell DA. Orchestration of enzymatic processing by thiazole/oxazole-modified microcin dehydrogenases. Biochemistry. 53: 413-22. PMID 24364559 DOI: 10.1021/Bi401529Y  0.586
2013 Lee J, Hao Y, Blair PM, Melby JO, Agarwal V, Burkhart BJ, Nair SK, Mitchell DA. Structural and functional insight into an unexpectedly selective N-methyltransferase involved in plantazolicin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 12954-9. PMID 23878226 DOI: 10.1073/Pnas.1306101110  0.54
2013 Deane CD, Melby JO, Molohon KJ, Susarrey AR, Mitchell DA. Engineering unnatural variants of plantazolicin through codon reprogramming. Acs Chemical Biology. 8: 1998-2008. PMID 23823732 DOI: 10.1021/Cb4003392  0.641
2012 Dunbar KL, Melby JO, Mitchell DA. YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations. Nature Chemical Biology. 8: 569-75. PMID 22522320 DOI: 10.1038/Nchembio.944  0.582
2012 Melby JO, Dunbar KL, Trinh NQ, Mitchell DA. Selectivity, directionality, and promiscuity in peptide processing from a Bacillus sp. Al Hakam cyclodehydratase. Journal of the American Chemical Society. 134: 5309-16. PMID 22401305 DOI: 10.1021/Ja211675N  0.63
2011 Molohon KJ, Melby JO, Lee J, Evans BS, Dunbar KL, Bumpus SB, Kelleher NL, Mitchell DA. Structure determination and interception of biosynthetic intermediates for the plantazolicin class of highly discriminating antibiotics. Acs Chemical Biology. 6: 1307-13. PMID 21950656 DOI: 10.1021/Cb200339D  0.697
2011 Melby JO, Nard NJ, Mitchell DA. Thiazole/oxazole-modified microcins: complex natural products from ribosomal templates. Current Opinion in Chemical Biology. 15: 369-78. PMID 21429787 DOI: 10.1016/J.Cbpa.2011.02.027  0.635
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