Vincent Seutin, Ph.D. / M.D - Publications

Affiliations: 
GIGA - Neurosciences University of Liège, Liège, Wallonie, Belgium 
Area:
Ventral tegmental area, substantia nigra, dorsal raphe, locus coeruleus
Website:
https://www.giganeurophy.uliege.be/cms/c_4242093/en/giganeurophy

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Porquet F, Weidong L, Jehasse K, Gazon H, Kondili M, Blacher S, Massotte L, Di Valentin E, Furling D, Gillet NA, Klein AF, Seutin V, Willems L. Specific -promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy. Nucleic Acids. 32: 857-871. PMID 37273786 DOI: 10.1016/j.omtn.2023.05.007  0.658
2023 van Herck IGM, Seutin V, Bentzen BH, Marrion NV, Edwards AG. Gating kinetics and pharmacological properties of small conductance calcium-activated potassium channels. Biophysical Journal. PMID 36760125 DOI: 10.1016/j.bpj.2023.02.004  0.319
2021 Jehasse K, Massotte L, Hartmann S, Vitello R, Ringlet S, Vitello M, Chua HC, Pless SA, Engel D, Liégeois JF, Lakaye B, Roeper J, Seutin V. The gating pore blocker 1-(2,4-xylyl)guanidinium selectively inhibits pacemaking of midbrain dopaminergic neurons. Neuropharmacology. 108722. PMID 34273387 DOI: 10.1016/j.neuropharm.2021.108722  0.795
2021 Jehasse K, Jacquerie K, de Froidmont A, Lemoine C, Grisar T, Stouffs K, Lakaye B, Seutin V. Functional analysis of the F337C mutation in the CLCN1 gene associated with dominant myotonia congenita reveals an alteration of the macroscopic conductance and voltage dependence. Molecular Genetics & Genomic Medicine. 9: e1588. PMID 33507632 DOI: 10.1002/mgg3.1588  0.761
2019 Destreel G, Seutin V, Engel D. Subsaturation of the NMDAR glycine site allows the regulation of bursting activity in juvenile rat nigral dopamine neurons. The European Journal of Neuroscience. PMID 31206829 DOI: 10.1111/Ejn.14491  0.505
2016 Philippart F, Destreel G, Merino-Sepúlveda P, Henny P, Engel D, Seutin V. Differential Somatic Ca2+ Channel Profile in Midbrain Dopaminergic Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7234-45. PMID 27383597 DOI: 10.1523/Jneurosci.0459-16.2016  0.793
2016 de Vrind V, Scuvée-Moreau J, Drion G, Hmaied C, Philippart F, Engel D, Seutin V. Interactions between calcium channels and SK channels in midbrain dopamine neurons and their impact on pacemaker regularity: contrasting roles of N- and l-type channels. European Journal of Pharmacology. PMID 27364758 DOI: 10.1016/J.Ejphar.2016.06.046  0.703
2016 Koulchitsky S, Delairesse C, Beeken T, Monteforte A, Dethier J, Quertemont E, Findeisen R, Bullinger E, Seutin V. Activation of D2 autoreceptors alters cocaine-induced locomotion and slows down local field oscillations in the rat ventral tegmental area. Neuropharmacology. 108: 120-7. PMID 27130904 DOI: 10.1016/j.neuropharm.2016.04.034  0.717
2015 Engel D, Seutin V. High dendritic expression of Ih in the proximity of the axon origin controls the integrative properties of nigral dopamine neurons. The Journal of Physiology. PMID 26350173 DOI: 10.1113/Jp271052  0.443
2014 Badarau E, Dilly S, Wouters J, Seutin V, Liégeois JF. Chemical modifications of the N-methyl-laudanosine scaffold point to new directions for SK channels exploration. Bioorganic & Medicinal Chemistry Letters. 24: 5616-20. PMID 25466186 DOI: 10.1016/j.bmcl.2014.10.083  0.395
2014 Alix P, Venkatesan K, Scuvée-Moreau J, Massotte L, Nguyen Trung ML, Cornil CA, Seutin V. Mechanism of the medium-duration afterhyperpolarization in rat serotonergic neurons. The European Journal of Neuroscience. 39: 186-96. PMID 24188044 DOI: 10.1111/ejn.12408  0.482
2013 Franci A, Drion G, Seutin V, Sepulchre R. A balance equation determines a switch in neuronal excitability. Plos Computational Biology. 9: e1003040. PMID 23717194 DOI: 10.1371/Journal.Pcbi.1003040  0.378
2012 Dilly S, Philippart F, Lamy C, Poncin S, Snyders D, Seutin V, Liégeois JF. The interactions of apamin and tetraethylammonium are differentially affected by single mutations in the pore mouth of small conductance calcium-activated potassium (SK) channels. Biochemical Pharmacology. 85: 560-9. PMID 23270990 DOI: 10.1016/J.Bcp.2012.12.015  0.683
2012 Drion G, Franci A, Seutin V, Sepulchre R. A novel phase portrait for neuronal excitability. Plos One. 7: e41806. PMID 22905107 DOI: 10.1371/Journal.Pone.0041806  0.305
2012 Dilly S, Poncin S, Lamy C, Liégeois JF, Seutin V. [Physiology, pharmacology and modelling of potassium channels: focus on SK channels]. Medecine Sciences : M/S. 28: 395-402. PMID 22549867 DOI: 10.1051/medsci/2012284017  0.462
2012 Koulchitsky S, De Backer B, Quertemont E, Charlier C, Seutin V. Differential effects of cocaine on dopamine neuron firing in awake and anesthetized rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1559-71. PMID 22298123 DOI: 10.1038/npp.2011.339  0.765
2011 Weatherall KL, Seutin V, Liégeois JF, Marrion NV. Crucial role of a shared extracellular loop in apamin sensitivity and maintenance of pore shape of small-conductance calcium-activated potassium (SK) channels Proceedings of the National Academy of Sciences of the United States of America. 108: 18494-18499. PMID 22025703 DOI: 10.1073/pnas.1110724108  0.431
2011 Badarau E, Dilly S, Dufour F, Poncin S, Seutin V, Liégeois JF. Synthesis and radioligand binding studies of bis-(8-isopropyl-isoquinolinium) derivatives as ligands for apamin-sensitive sites on cloned SK2 and SK3 channels. Bioorganic & Medicinal Chemistry Letters. 21: 6756-9. PMID 21978678 DOI: 10.1016/j.bmcl.2011.09.043  0.317
2011 Dilly S, Lamy C, Marrion NV, Liégeois JF, Seutin V. Ion-Channel Modulators: More Diversity Than Previously Thought Chembiochem. 12: 1808-1812. PMID 21726033 DOI: 10.1002/cbic.201100236  0.395
2011 Drion G, Massotte L, Sepulchre R, Seutin V. How modeling can reconcile apparently discrepant experimental results: the case of pacemaking in dopaminergic neurons. Plos Computational Biology. 7: e1002050. PMID 21637742 DOI: 10.1371/Journal.Pcbi.1002050  0.462
2010 Lamy C, Goodchild SJ, Weatherall KL, Jane DE, Liégeois JF, Seutin V, Marrion NV. Allosteric block of KCa2 channels by apamin. The Journal of Biological Chemistry. 285: 27067-77. PMID 20562108 DOI: 10.1074/Jbc.M110.110072  0.395
2010 Lamy C, Scuvée-Moreau J, Dilly S, Liégeois JF, Seutin V. The sigma agonist 1,3-di-o-tolyl-guanidine directly blocks SK channels in dopaminergic neurons and in cell lines. European Journal of Pharmacology. 641: 23-8. PMID 20546722 DOI: 10.1016/j.ejphar.2010.05.008  0.391
2010 Seutin V, Engel D. Differences in Na+ conductance density and Na+ channel functional properties between dopamine and GABA neurons of the rat substantia nigra. Journal of Neurophysiology. 103: 3099-114. PMID 20357070 DOI: 10.1152/Jn.00513.2009  0.599
2010 Drion G, Bonjean M, Waroux O, Scuvée-Moreau J, Liégeois JF, Sejnowski TJ, Sepulchre R, Seutin V. M-type channels selectively control bursting in rat dopaminergic neurons. The European Journal of Neuroscience. 31: 827-35. PMID 20180842 DOI: 10.1111/J.1460-9568.2010.07107.X  0.827
2009 Goodchild SJ, Lamy C, Seutin V, Marrion NV. Inhibition of KCa2.2 and KCa2.3 channel currents by protonation of outer pore histidine residues Journal of General Physiology. 134: 295-308. PMID 19786583 DOI: 10.1085/jgp.200910252  0.325
2008 Rouchet N, Waroux O, Lamy C, Massotte L, Scuvée-Moreau J, Liégeois JF, Seutin V. SK channel blockade promotes burst firing in dorsal raphe serotonergic neurons. The European Journal of Neuroscience. 28: 1108-15. PMID 18783364 DOI: 10.1111/j.1460-9568.2008.06430.x  0.817
2008 Graulich A, Lamy C, Alleva L, Dilly S, Chavatte P, Wouters J, Seutin V, Liégeois JF. Bis-tetrahydroisoquinoline derivatives: AG525E1, a new step in the search for non-quaternary non-peptidic small conductance Ca(2+)-activated K(+) channel blockers. Bioorganic & Medicinal Chemistry Letters. 18: 3440-5. PMID 18436444 DOI: 10.1016/j.bmcl.2008.03.069  0.337
2008 Hansen HH, Waroux O, Seutin V, Jentsch TJ, Aznar S, Mikkelsen JD. Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS. The Journal of Physiology. 586: 1823-32. PMID 18174210 DOI: 10.1113/Jphysiol.2007.149450  0.817
2007 Graulich A, Dilly S, Farce A, Scuvée-Moreau J, Waroux O, Lamy C, Chavatte P, Seutin V, Liégeois JF. Synthesis and radioligand binding studies of bis-isoquinolinium derivatives as small conductance Ca(2+)-activated K(+) channel blockers. Journal of Medicinal Chemistry. 50: 5070-5. PMID 17867663 DOI: 10.1021/jm070412j  0.8
2007 Seutin V, Liégeois JF. SK channels are on the move. British Journal of Pharmacology. 151: 568-70. PMID 17486139 DOI: 10.1038/sj.bjp.0707282  0.432
2006 Graulich A, Scuvée-Moreau J, Alleva L, Lamy C, Waroux O, Seutin V, Liégeois JF. Synthesis and radioligand binding studies of methoxylated 1,2,3,4-tetrahydroisoquinolinium derivatives as ligands of the apamin-sensitive Ca2+-activated K+ channels. Journal of Medicinal Chemistry. 49: 7208-14. PMID 17125273 DOI: 10.1021/jm0607395  0.763
2006 Hansen HH, Ebbesen C, Mathiesen C, Weikop P, Rønn LC, Waroux O, Scuvée-Moreau J, Seutin V, Mikkelsen JD. The KCNQ channel opener retigabine inhibits the activity of mesencephalic dopaminergic systems of the rat. The Journal of Pharmacology and Experimental Therapeutics. 318: 1006-19. PMID 16775195 DOI: 10.1124/jpet.106.106757  0.836
2005 Dilly S, Graulich A, Farce A, Seutin V, Liegeois JF, Chavatte P. Identification of a pharmacophore of SKCa channel blockers. Journal of Enzyme Inhibition and Medicinal Chemistry. 20: 517-23. PMID 16408787 DOI: 10.1080/14756360500210989  0.395
2005 Waroux O, Massotte L, Alleva L, Graulich A, Thomas E, Liégeois JF, Scuvée-Moreau J, Seutin V. SK channels control the firing pattern of midbrain dopaminergic neurons in vivo. The European Journal of Neuroscience. 22: 3111-21. PMID 16367777 DOI: 10.1111/j.1460-9568.2005.04484.x  0.811
2005 Seutin V. Dopaminergic neurones: much more than dopamine? British Journal of Pharmacology. 146: 167-9. PMID 16025140 DOI: 10.1038/sj.bjp.0706328  0.303
2005 Graulich A, Mercier F, Scuvée-Moreau J, Seutin V, Liégeois JF. Synthesis and biological evaluation of N-methyl-laudanosine iodide analogues as potential SK channel blockers. Bioorganic & Medicinal Chemistry. 13: 1201-9. PMID 15670929 DOI: 10.1016/J.BMC.2004.11.025  0.475
2004 Cornil CA, Seutin V, Motte P, Balthazart J. Electrophysiological and neurochemical characterization of neurons of the medial preoptic area in Japanese quail (Coturnix japonica). Brain Research. 1029: 224-40. PMID 15542078 DOI: 10.1016/j.brainres.2004.09.047  0.334
2004 Scuvée-Moreau J, Boland A, Graulich A, Van Overmeire L, D'hoedt D, Graulich-Lorge F, Thomas E, Abras A, Stocker M, Liégeois JF, Seutin V. Electrophysiological characterization of the SK channel blockers methyl-laudanosine and methyl-noscapine in cell lines and rat brain slices. British Journal of Pharmacology. 143: 753-64. PMID 15504758 DOI: 10.1038/sj.bjp.0705979  0.375
2003 Liégeois JF, Mercier F, Graulich A, Graulich-Lorge F, Scuvée-Moreau J, Seutin V. Modulation of small conductance calcium-activated potassium (SK) channels: a new challenge in medicinal chemistry. Current Medicinal Chemistry. 10: 625-47. PMID 12678783 DOI: 10.2174/0929867033457908  0.484
2002 Scuvee-Moreau J, Liegeois JF, Massotte L, Seutin V. Methyl-laudanosine: a new pharmacological tool to investigate the function of small-conductance Ca(2+)-activated K(+) channels. The Journal of Pharmacology and Experimental Therapeutics. 302: 1176-83. PMID 12183678 DOI: 10.1124/jpet.302.3.1176  0.492
2001 Seutin V, Massotte L, Renette MF, Dresse A. Evidence for a modulatory role of Ih on the firing of a subgroup of midbrain dopamine neurons. Neuroreport. 12: 255-8. PMID 11209930 DOI: 10.1097/00001756-200102120-00015  0.381
2000 Seutin V, Mkahli F, Massotte L, Dresse A. Calcium release from internal stores is required for the generation of spontaneous hyperpolarizations in dopaminergic neurons of neonatal rats. Journal of Neurophysiology. 83: 192-7. PMID 10634866 DOI: 10.1152/JN.2000.83.1.192  0.379
1999 Seutin V, Massotte L, Scuvée-Moreau J, Dresse A. Spontaneous apamin-sensitive hyperpolarizations in dopaminergic neurons of neonatal rats. Journal of Neurophysiology. 80: 3361-4. PMID 9862933 DOI: 10.1152/JN.1998.80.6.3361  0.337
1998 Scuvée-Moreau J, Seutin V, Vrijens B, Pirotte B, De Tullio P, Massotte L, Albert A, Delarge J, Dresse A. Effect of potassium channel openers on the firing rate of hippocampal pyramidal cells and A10 dopaminergic neurons in vitro. Archives of Physiology and Biochemistry. 105: 421-8. PMID 9439778 DOI: 10.1076/APAB.105.5.421.3285  0.407
1997 Johnson SW, Seutin V. Bicuculline methiodide potentiates NMDA-dependent burst firing in rat dopamine neurons by blocking apamin-sensitive Ca2+-activated K+ currents. Neuroscience Letters. 231: 13-6. PMID 9280156 DOI: 10.1016/S0304-3940(97)00508-9  0.348
1996 Seutin V, Shen KZ, North RA, Johnson SW. Sulfonylurea-sensitive potassium current evoked by sodium-loading in rat midbrain dopamine neurons. Neuroscience. 71: 709-19. PMID 8867043 DOI: 10.1016/0306-4522(95)00489-0  0.486
1995 Seutin V, Scuvée-Moreau J, Massotte L, Dresse A. Hydrogen peroxide hyperpolarizes rat CA1 pyramidal neurons by inducing an increase in potassium conductance. Brain Research. 683: 275-8. PMID 7552366 DOI: 10.1016/0006-8993(95)00436-T  0.408
1994 Seutin V, Johnson SW, North RA. Effect of dopamine and baclofen on N-methyl-D-aspartate-induced burst firing in rat ventral tegmental neurons. Neuroscience. 58: 201-6. PMID 8159294 DOI: 10.1016/0306-4522(94)90167-8  0.533
1993 Seutin V, Johnson SW, North RA. Apamin increases NMDA-induced burst-firing of rat mesencephalic dopamine neurons. Brain Research. 630: 341-4. PMID 8118703 DOI: 10.1016/0006-8993(93)90675-D  0.554
1992 Johnson SW, Seutin V, North RA. Burst firing in dopamine neurons induced by N-methyl-D-aspartate: role of electrogenic sodium pump. Science (New York, N.Y.). 258: 665-7. PMID 1329209 DOI: 10.1126/SCIENCE.1329209  0.533
1991 Seutin V, Scuvée-Moreau J, Giesbers I, Massotte L, Dresse A. Effect of BHT 920 on monoaminergic neurons of the rat brain: an electrophysiological in vivo and in vitro study. Naunyn-Schmiedeberg's Archives of Pharmacology. 342: 502-7. PMID 1982557 DOI: 10.1007/BF00169036  0.322
1991 Seutin V, Verbanck P, Massotte L, Dresse A. Acute amphetamine-induced subsensitivity of A10 dopamine autoreceptors in vitro. Brain Research. 558: 141-4. PMID 1933376 DOI: 10.1016/0006-8993(91)90731-A  0.33
1990 Seutin V, Franchimont N, Massotte L, Dresse A. Comparison of the effect of morphine on locus coeruleus noradrenergic and ventral tegmental area dopaminergic neurons in vitro. Life Sciences. 46: 1879-85. PMID 2163482 DOI: 10.1016/0024-3205(90)90241-I  0.321
1989 Seutin V, Massotte L, Dresse A. Electrophysiological effects of neurotensin on dopaminergic neurones of the ventral tegmental area of the rat in vitro. Neuropharmacology. 28: 949-54. PMID 2572997 DOI: 10.1016/0028-3908(89)90194-9  0.337
1989 Seutin V, Verbanck P, Massotte L, Dresse A. Galanin decreases the activity of locus coeruleus neurons in vitro. European Journal of Pharmacology. 164: 373-6. PMID 2474450 DOI: 10.1016/0014-2999(89)90481-0  0.312
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