Jonathan Lytton - Publications

Affiliations: 
University of Calgary, Calgary, Alberta, Canada 

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chan B, Cheng IC, Rozita J, Gorshteyn I, Huang Y, Shaffer I, Chang C, Li W, Lytton J, Den Besten P, Zhang Y. Sodium/(calcium + potassium) exchanger NCKX4 optimizes KLK4 activity in the enamel matrix microenvironment to regulate ECM modeling. Frontiers in Physiology. 14: 1116091. PMID 36814474 DOI: 10.3389/fphys.2023.1116091  0.373
2022 Al-Khannaq M, Lytton J. Regulation of K-Dependent Na/Ca-Exchangers (NCKX). International Journal of Molecular Sciences. 24. PMID 36614039 DOI: 10.3390/ijms24010598  0.51
2022 Cuomo O, Sirabella R, Boscia F, Casamassa A, Lytton J, Annunziato L, Pignataro G. K-Dependent Na/Ca Exchanger Isoform 2, Nckx2, Takes Part in the Neuroprotection Elicited by Ischemic Preconditioning in Brain Ischemia. International Journal of Molecular Sciences. 23. PMID 35806133 DOI: 10.3390/ijms23137128  0.396
2020 Thibodeau S, Yang W, Sharma S, Lytton J. Calmodulin binds and modulates K-dependent Na/Ca-exchanger isoform 4, NCKX4. The Journal of Biological Chemistry. PMID 33199372 DOI: 10.1074/jbc.RA120.015037  0.597
2019 Hassan MT, Lytton J. Potassium-dependent sodium-calcium exchanger (NCKX) isoforms and neuronal function. Cell Calcium. 86: 102135. PMID 31846835 DOI: 10.1016/j.ceca.2019.102135  0.471
2016 Bronckers AL, Jalali R, Lytton J. Reduced Protein Expression of the Na/Ca+K-Exchanger (SLC24A4) in Apical Plasma Membranes of Maturation Ameloblasts of Fluorotic Mice. Calcified Tissue International. 100: 80-86. PMID 27752731 DOI: 10.1007/s00223-016-0197-4  0.411
2015 Zhang Y, Sharma S, Lytton J. Anatomical evidence for a non-synaptic influence of the K(+)-Dependent Na(+)/Ca(2+)-exchanger, NCKX2, on hippocampal plasticity. Neuroscience. PMID 26410028 DOI: 10.1016/j.neuroscience.2015.09.049  0.479
2014 Li XF, Lytton J. An essential role for the K+-dependent Na+/Ca2+-exchanger, NCKX4, in melanocortin-4-receptor-dependent satiety. The Journal of Biological Chemistry. 289: 25445-59. PMID 25096581 DOI: 10.1074/jbc.M114.564450  0.567
2013 Yang X, Lytton J. Purinergic stimulation of K+-dependent Na+/Ca2+ exchanger isoform 4 requires dual activation by PKC and CaMKII. Bioscience Reports. 33. PMID 24224486 DOI: 10.1042/BSR20130099  0.547
2011 Zhang Y, Turner RW, Lytton J. Analyzing the Role of NCKX2 in Hippocampal Long Term Potentiation Biophysical Journal. 100: 548a. DOI: 10.1016/J.BPJ.2010.12.3192  0.495
2009 Chandrasekera PC, Kargacin ME, Deans JP, Lytton J. Determination of apparent calcium affinity for endogenously expressed human sarco(endo)plasmic reticulum calcium-ATPase isoform SERCA3. American Journal of Physiology. Cell Physiology. 296: C1105-14. PMID 19225163 DOI: 10.1152/ajpcell.00650.2008  0.56
2008 Cuomo O, Gala R, Pignataro G, Boscia F, Secondo A, Scorziello A, Pannaccione A, Viggiano D, Adornetto A, Molinaro P, Li XF, Lytton J, Di Renzo G, Annunziato L. A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2053-63. PMID 18305240 DOI: 10.1523/JNEUROSCI.4912-07.2008  0.463
2007 Lytton J. Na+/Ca2+ exchangers: three mammalian gene families control Ca2+ transport. The Biochemical Journal. 406: 365-82. PMID 17716241 DOI: 10.1042/BJ20070619  0.649
2007 Visser F, Lytton J. K+ -dependent Na+/Ca2+ exchangers: key contributors to Ca2+ signaling. Physiology (Bethesda, Md.). 22: 185-92. PMID 17557939 DOI: 10.1152/physiol.00001.2007  0.612
2007 Cuomo O, Pignataro G, Gala R, Boscia F, Tortiglione A, Molinaro P, Di Renzo G, Lytton J, Annunziato L. Involvement of the potassium-dependent sodium/calcium exchanger gene product NCKX2 in the brain insult induced by permanent focal cerebral ischemia. Annals of the New York Academy of Sciences. 1099: 486-9. PMID 17446491 DOI: 10.1196/annals.1387.051  0.364
2007 Visser F, Valsecchi V, Annunziato L, Lytton J. Exchangers NCKX2, NCKX3, and NCKX4: identification of Thr-551 as a key residue in defining the apparent K(+) affinity of NCKX2. The Journal of Biological Chemistry. 282: 4453-4462. PMID 17172467 DOI: 10.1074/jbc.M610582200  0.566
2006 Lee JY, Visser F, Lee JS, Lee KH, Soh JW, Ho WK, Lytton J, Lee SH. Protein kinase C-dependent enhancement of activity of rat brain NCKX2 heterologously expressed in HEK293 cells. The Journal of Biological Chemistry. 281: 39205-16. PMID 17038313 DOI: 10.1074/Jbc.M606287200  0.435
2006 Riedel MJ, Baczkó I, Searle GJ, Webster N, Fercho M, Jones L, Lang J, Lytton J, Dyck JR, Light PE. Metabolic regulation of sodium-calcium exchange by intracellular acyl CoAs. The Embo Journal. 25: 4605-14. PMID 16977318 DOI: 10.1038/sj.emboj.7601321  0.368
2006 Dong H, Jiang Y, Triggle CR, Li X, Lytton J. Novel role for K+-dependent Na+/Ca2+ exchangers in regulation of cytoplasmic free Ca2+ and contractility in arterial smooth muscle. American Journal of Physiology. Heart and Circulatory Physiology. 291: H1226-35. PMID 16617138 DOI: 10.1152/Ajpheart.00196.2006  0.618
2006 Li XF, Kiedrowski L, Tremblay F, Fernandez FR, Perizzolo M, Winkfein RJ, Turner RW, Bains JS, Rancourt DE, Lytton J. Importance of K+-dependent Na+/Ca2+-exchanger 2, NCKX2, in motor learning and memory. The Journal of Biological Chemistry. 281: 6273-82. PMID 16407245 DOI: 10.1074/jbc.M512137200  0.564
2006 Zhang XQ, Song J, Tadros GM, Rothblum LI, Dunn J, Lytton J, Cheung JY. Na+/Ca2+ exchanger is functional in both Ca2+ influx and efflux modes in rat myocytes Annals of the New York Academy of Sciences. 976: 528-529. DOI: 10.1111/J.1749-6632.2002.Tb04787.X  0.561
2004 Kiedrowski L, Czyz A, Baranauskas G, Li XF, Lytton J. Differential contribution of plasmalemmal Na/Ca exchange isoforms to sodium-dependent calcium influx and NMDA excitotoxicity in depolarized neurons. Journal of Neurochemistry. 90: 117-28. PMID 15198672 DOI: 10.1111/j.1471-4159.2004.02462.x  0.557
2004 Cai X, Lytton J. The cation/Ca(2+) exchanger superfamily: phylogenetic analysis and structural implications. Molecular Biology and Evolution. 21: 1692-703. PMID 15163769 DOI: 10.1093/molbev/msh177  0.698
2004 Cai X, Lytton J. Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6. The Journal of Biological Chemistry. 279: 5867-76. PMID 14625281 DOI: 10.1074/jbc.M310908200  0.709
2003 Chandrasekera CP, Lytton J. Inhibition of human SERCA3 by PL/IM430. Molecular analysis of the interaction. The Journal of Biological Chemistry. 278: 12482-8. PMID 12540840 DOI: 10.1074/jbc.M212745200  0.472
2002 Lytton J, Li XF, Dong H, Kraev A. K+-dependent Na+/Ca2+ exchangers in the brain. Annals of the New York Academy of Sciences. 976: 382-93. PMID 12502585 DOI: 10.1111/j.1749-6632.2002.tb04765.x  0.614
2002 Lytton J, Dong H. Rat heart NCX1.1 stoichiometry measured in a transfected cell system. Annals of the New York Academy of Sciences. 976: 137-41. PMID 12502552 DOI: 10.1111/j.1749-6632.2002.tb04732.x  0.542
2002 Cai X, Zhang K, Lytton J. Topological studies of the rat brain K+-dependent Na+/Ca2+ exchanger NCKX2. Annals of the New York Academy of Sciences. 976: 90-3. PMID 12502542 DOI: 10.1111/j.1749-6632.2002.tb04722.x  0.67
2002 Li XF, Lytton J. Differential expression of Na/Ca exchanger and Na/Ca + K exchanger transcripts in rat brain. Annals of the New York Academy of Sciences. 976: 64-6. PMID 12502535 DOI: 10.1111/j.1749-6632.2002.tb04715.x  0.622
2002 Cai X, Zhang K, Lytton J. A novel topology and redox regulation of the rat brain K+-dependent Na+/Ca2+ exchanger, NCKX2. The Journal of Biological Chemistry. 277: 48923-30. PMID 12377762 DOI: 10.1074/jbc.M208818200  0.639
2002 Tadros GM, Zhang XQ, Song J, Carl LL, Rothblum LI, Tian Q, Dunn J, Lytton J, Cheung JY. Effects of Na(+)/Ca(2+) exchanger downregulation on contractility and [Ca(2+)](i) transients in adult rat myocytes. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1616-26. PMID 12234816 DOI: 10.1152/Ajpheart.00186.2002  0.557
2002 Kiedrowski L, Czyz A, Li XF, Lytton J. Preferential expression of plasmalemmal K-dependent Na+/Ca2+ exchangers in neurons versus astrocytes. Neuroreport. 13: 1529-32. PMID 12218699 DOI: 10.1097/00001756-200208270-00008  0.535
2002 Dunn J, Elias CL, Le HD, Omelchenko A, Hryshko LV, Lytton J. The molecular determinants of ionic regulatory differences between brain and kidney Na+/Ca2+ exchanger (NCX1) isoforms. The Journal of Biological Chemistry. 277: 33957-62. PMID 12118014 DOI: 10.1074/jbc.M206677200  0.571
2002 Dong H, Dunn J, Lytton J. Stoichiometry of the Cardiac Na+/Ca2+ exchanger NCX1.1 measured in transfected HEK cells. Biophysical Journal. 82: 1943-52. PMID 11916852 DOI: 10.1016/S0006-3495(02)75543-4  0.552
2001 Zhang XQ, Song J, Rothblum LI, Lun M, Wang X, Ding F, Dunn J, Lytton J, McDermott PJ, Cheung JY. Overexpression of Na+/Ca2+ exchanger alters contractility and SR Ca2+ content in adult rat myocytes American Journal of Physiology-Heart and Circulatory Physiology. 281. PMID 11668069 DOI: 10.1152/Ajpheart.2001.281.5.H2079  0.504
2001 Dong H, Light PE, French RJ, Lytton J. Electrophysiological characterization and ionic stoichiometry of the rat brain K(+)-dependent NA(+)/CA(2+) exchanger, NCKX2. The Journal of Biological Chemistry. 276: 25919-28. PMID 11342562 DOI: 10.1074/jbc.M103401200  0.545
2001 Kraev A, Quednau BD, Leach S, Li XF, Dong H, Winkfein R, Perizzolo M, Cai X, Yang R, Philipson KD, Lytton J. Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3. The Journal of Biological Chemistry. 276: 23161-72. PMID 11294880 DOI: 10.1074/JBC.M102314200  0.71
2001 Wu KD, Bungard D, Lytton J. Regulation of SERCA Ca2+ pump expression by cytoplasmic [Ca2+] in vascular smooth muscle cells American Journal of Physiology - Cell Physiology. 280. PMID 11245601 DOI: 10.1152/AJPCELL.2001.280.4.C843  0.474
2000 DUNN J, Elias C, Hryshko L, Lytton J. Residues involved in the isoform specific ionic regulation of Na+/Ca2+ exchanger function Biochemical Society Transactions. 28: A389-A389. DOI: 10.1042/BST028A389B  0.584
1999 Horiguchi M, Kimura M, Lytton J, Poch E, Aviv A. The relationship between Ca2+-ATPase and freely exchangeable Ca2+ in the dense tubules: a study in platelets from women. American Journal of Hypertension. 12: 120-7. PMID 10090338 DOI: 10.1016/S0895-7061(98)00214-3  0.412
1999 Li XF, Lytton J. A circularized sodium-calcium exchanger exon 2 transcript. The Journal of Biological Chemistry. 274: 8153-60. PMID 10075718 DOI: 10.1074/jbc.274.12.8153  0.412
1998 Poch E, Leach S, Snape S, Cacic T, MacLennan DH, Lytton J. Functional characterization of alternatively spliced human SERCA3 transcripts. The American Journal of Physiology. 275: C1449-58. PMID 9843705 DOI: 10.1152/Ajpcell.1998.275.6.C1449  0.656
1998 Loukianov E, Ji Y, Grupp IL, Kirkpatrick DL, Baker DL, Loukianova T, Grupp G, Lytton J, Walsh RA, Periasamy M. Enhanced myocardial contractility and increased Ca2+ transport function in transgenic hearts expressing the fast-twitch skeletal muscle sarcoplasmic reticulum Ca2+-ATPase. Circulation Research. 83: 889-97. PMID 9797337 DOI: 10.1161/01.RES.83.9.889  0.379
1998 Tsoi M, Rhee KH, Bungard D, Li XF, Lee SL, Auer RN, Lytton J. Molecular cloning of a novel potassium-dependent sodium-calcium exchanger from rat brain. The Journal of Biological Chemistry. 273: 4155-62. PMID 9461611 DOI: 10.1074/jbc.273.7.4155  0.362
1998 Horiguchi M, Kimura M, Lytton J, Skurnick J, Nash F, Awad G, Poch E, Aviv A. Ca2+ in the dense tubules: a model of platelet Ca2+ load. Hypertension. 31: 595-602. PMID 9461227 DOI: 10.1161/01.HYP.31.2.595  0.462
1997 Zhao M, Lytton J, Burchiel SW. Inhibition of sarco-endoplasmic reticulum calcium ATPases (SERCA) by polycyclic aromatic hydrocarbons: lack of evidence for direct effects on cloned rat enzymes. International Journal of Immunopharmacology. 18: 589-98. PMID 9080252 DOI: 10.1016/S0192-0561(96)00063-X  0.418
1997 Van Baal J, Yu A, Hartog A, Fransen JA, Willems PH, Lytton J, Bindels RJ. Localization and regulation by vitamin D of calcium transport proteins in rabbit cortical collecting system. The American Journal of Physiology. 271: F985-93. PMID 8945992 DOI: 10.1152/AJPRENAL.1996.271.5.F985  0.581
1996 Kaplan MR, Plotkin MD, Lee WS, Xu ZC, Lytton J, Hebert SC. Apical localization of the Na-K-Cl cotransporter, rBSC1, on rat thick ascending limbs. Kidney International. 49: 40-7. PMID 8770947  0.337
1995 Krieger JA, Davila DR, Lytton J, Born JL, Burchiel SW. Inhibition of sarcoplasmic/endoplasmic reticulum calcium ATPases (SERCA) by polycyclic aromatic hydrocarbons in HPB-ALL human T cells and other tissues. Toxicology and Applied Pharmacology. 133: 102-8. PMID 7597699 DOI: 10.1006/Taap.1995.1131  0.54
1995 Wu KD, Lee WS, Wey J, Bungard D, Lytton J. Localization and quantification of endoplasmic reticulum Ca2+-ATPase isoform transcripts American Journal of Physiology - Cell Physiology. 269. PMID 7573409 DOI: 10.1152/AJPCELL.1995.269.3.C775  0.458
1993 Gamba G, Saltzberg SN, Lombardi M, Miyanoshita A, Lytton J, Hediger MA, Brenner BM, Hebert SC. Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter Proceedings of the National Academy of Sciences of the United States of America. 90: 2749-2753. PMID 8464884  0.351
1993 Wu KD, Lytton J. Molecular cloning and quantification of sarcoplasmic reticulum Ca2+- ATPase isoforms in rat muscles American Journal of Physiology - Cell Physiology. 264. PMID 8447366 DOI: 10.1152/AJPCELL.1993.264.2.C333  0.358
1993 Brown EM, Gamba G, Riccardi D, Lombardi M, Butters R, Kifor O, Sun A, Hediger MA, Lytton J, Hebert SC. Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid Nature. 366: 575-580. PMID 8255296  0.443
1992 Yu ASL, Hebert SC, Lee SL, Brenner BM, Lytton J. Identification and localization of renal Na+-Ca2+ exchanger by polymerase chain reaction American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 263. PMID 1415740  0.529
1992 MacLennan DH, Toyofuku T, Lytton J. Structure-function relationships in sarcoplasmic or endoplasmic reticulum type Ca2+ pumps. Annals of the New York Academy of Sciences. 671: 1-10. PMID 1337665 DOI: 10.1111/J.1749-6632.1992.Tb43779.X  0.613
1992 Yu ASL, Hebert SC, Brenner BM, Lytton J. Molecular characterization and nephron distribution of a family of transcripts encoding the pore-forming subunit of Ca2+ channels in the kidney Proceedings of the National Academy of Sciences of the United States of America. 89: 10494-10498. PMID 1279681  0.493
1992 Toyofuku T, Kurzydlowski K, Lytton J, MacLennan D. The nucleotide binding/hinge domain plays a crucial role in determining isoform-specific Ca2+ dependence of organellar Ca(2+)-ATPases. Journal of Biological Chemistry. 267: 14490-14496. DOI: 10.1016/S0021-9258(19)49739-1  0.506
1991 Lytton J, Westlin M, Hanley MR. Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. The Journal of Biological Chemistry. 266: 17067-71. PMID 1832668  0.335
1989 Lytton J, Zarain-Herzberg A, Periasamy M, MacLennan DH. Molecular Cloning of the Mammalian Smooth Muscle Sarco(endo)plasmic Reticulum Ca2+-ATPase Journal of Biological Chemistry. 264: 7059-7065. DOI: 10.1016/s0021-9258(18)83540-2  0.455
1989 Burk SE, Lytton J, MacLennan DH, Shull GE. cDNA Cloning, functional expression, and mRNA Tissue Distribution of a Third Organellar Ca2+ Pump Journal of Biological Chemistry. 264: 18561-18568. DOI: 10.1016/s0021-9258(18)51504-0  0.437
1988 Fujii J, Lytton J, Tada M, MacLennan DH. Rabbit cardiac and slow-twitch muscle express the same phospholamban gene. Febs Letters. 227: 51-5. PMID 2962883 DOI: 10.1016/0014-5793(88)81412-1  0.448
1988 Lytton J, MacLennan DH. Molecular cloning of cDNAs from human kidney coding for two alternatively spliced products of the cardiac Ca2+-ATPase gene. Journal of Biological Chemistry. 263: 15024-15031. DOI: 10.1016/s0021-9258(18)68141-4  0.406
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