☰

cached image

Marie E. Egan, M.D. - Publications

Affiliations: 
Yale University, New Haven, CT 
Tree Info Similar researchers PubMed Report error

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Piotrowski-Daspit AS, Barone C, Lin CY, Deng Y, Wu D, Binns TC, Xu E, Ricciardi AS, Putman R, Garrison A, Nguyen R, Gupta A, Fan R, Glazer PM, Saltzman WM, ... Egan ME, et al. In vivo correction of cystic fibrosis mediated by PNA nanoparticles. Science Advances. 8: eabo0522. PMID 36197984 DOI: 10.1126/sciadv.abo0522  0.702
2022 Luks VL, Mandl H, DiRito J, Barone C, Freedman-Weiss MR, Ricciardi AS, Tietjen GG, Egan ME, Saltzman WM, Stitelman DH. Surface conjugation of antibodies improves nanoparticle uptake in bronchial epithelial cells. Plos One. 17: e0266218. PMID 35385514 DOI: 10.1371/journal.pone.0266218  0.568
2021 Ullrich SJ, Freedman-Weiss M, Ahle S, Mandl HK, Piotrowski-Daspit AS, Roberts K, Yung N, Maassel N, Bauer-Pisani T, Ricciardi AS, Egan ME, Glazer PM, Saltzman WM, Stitelman DH. Nanoparticles for Delivery of Agents to Fetal Lungs. Acta Biomaterialia. PMID 33484911 DOI: 10.1016/j.actbio.2021.01.024  0.627
2020 Egan ME. Emerging Technologies for Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Restoration in all People with CF. Pediatric Pulmonology. PMID 32681713 DOI: 10.1002/Ppul.24965  0.371
2020 Schupp JC, Khanal S, Gomez JL, Sauler M, Adams TS, Chupp GL, Yan X, Poli S, Zhao Y, Montgomery RR, Rosas IO, Dela Cruz CS, Bruscia EM, Egan ME, Kaminski N, et al. Single Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 32603604 DOI: 10.1164/Rccm.202004-0991Oc  0.402
2020 Egan ME. Cystic fibrosis transmembrane conductance receptor modulator therapy in cystic fibrosis, an update. Current Opinion in Pediatrics. 32: 384-388. PMID 32374578 DOI: 10.1097/Mop.0000000000000892  0.37
2020 Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, ... ... Egan M, et al. Global chemical effects of the microbiome include new bile-acid conjugations. Nature. PMID 32103176 DOI: 10.1038/S41586-020-2047-9  0.301
2017 Di Pietro C, Zhang PX, O'Rourke TK, Murray TS, Wang L, Britto CJ, Koff JL, Krause DS, Egan ME, Bruscia EM. Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophages. Scientific Reports. 7: 10882. PMID 28883468 DOI: 10.1038/S41598-017-11012-7  0.343
2017 Egan ME. Effects of Lumacaftor/Ivacaftor in a Pediatric Cohort Homozygous for F508del-CFTR. American Journal of Respiratory and Critical Care Medicine. 195: 849-850. PMID 28362199 DOI: 10.1164/Rccm.201611-2290Ed  0.314
2016 Knauf F, Thomson RB, Heneghan JF, Jiang Z, Adebamiro A, Thomson CL, Barone C, Asplin JR, Egan ME, Alper SL, Aronson PS. Loss of Cystic Fibrosis Transmembrane Regulator Impairs Intestinal Oxalate Secretion. Journal of the American Society of Nephrology : Jasn. PMID 27313231 DOI: 10.1681/Asn.2016030279  0.377
2016 Hegan PS, Chandhoke SK, Barone C, Egan M, Bähler M, Mooseker MS. Mice lacking myosin IXb, an inflammatory bowel disease susceptibility gene, have impaired intestinal barrier function and superficial ulceration in the ileum. Cytoskeleton (Hoboken, N.J.). PMID 26972322 DOI: 10.1002/Cm.21292  0.304
2016 Egan ME. Genetics of Cystic Fibrosis: Clinical Implications. Clinics in Chest Medicine. 37: 9-16. PMID 26857764 DOI: 10.1016/J.Ccm.2015.11.002  0.458
2016 Bruscia E, Zhang PX, Barone C, Scholte B, Homer RJ, Krause D, Egan ME. Increased susceptibility of cftr-/- mice to LPS-induced lung remodeling. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00284.2015. PMID 26851259 DOI: 10.1152/Ajplung.00284.2015  0.434
2015 McNeer NA, Anandalingam K, Fields RJ, Caputo C, Kopic S, Gupta A, Quijano E, Polikoff L, Kong Y, Bahal R, Geibel JP, Glazer PM, Saltzman WM, Egan ME. Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium. Nature Communications. 6: 6952. PMID 25914116 DOI: 10.1038/Ncomms7952  0.689
2015 Zhang PX, Cheng J, Zou S, D'Souza AD, Koff JL, Lu J, Lee PJ, Krause DS, Egan ME, Bruscia EM. Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation. Nature Communications. 6: 6221. PMID 25665524 DOI: 10.1038/Ncomms7221  0.37
2015 Vanstone MB, Egan ME, Zhang JH, Carpenter TO. Association between serum 25-hydroxyvitamin D level and pulmonary exacerbations in cystic fibrosis. Pediatric Pulmonology. 50: 441-6. PMID 25657016 DOI: 10.1002/Ppul.23161  0.324
2015 Conrad C, Lymp J, Thompson V, Dunn C, Davies Z, Chatfield B, Nichols D, Clancy J, Vender R, Egan ME, Quittell L, Michelson P, Antony V, Spahr J, Rubenstein RC, et al. Long-term treatment with oral N-acetylcysteine: affects lung function but not sputum inflammation in cystic fibrosis subjects. A phase II randomized placebo-controlled trial. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 14: 219-27. PMID 25228446 DOI: 10.1016/J.Jcf.2014.08.008  0.329
2015 Fields RJ, Quijano E, McNeer NA, Caputo C, Bahal R, Anandalingam K, Egan ME, Glazer PM, Saltzman WM. Modified poly(lactic-co-glycolic acid) nanoparticles for enhanced cellular uptake and gene editing in the lung. Advanced Healthcare Materials. 4: 361-6. PMID 25156908 DOI: 10.1002/Adhm.201400355  0.67
2013 Zhang PX, Murray TS, Villella VR, Ferrari E, Esposito S, D'Souza A, Raia V, Maiuri L, Krause DS, Egan ME, Bruscia EM. Reduced caveolin-1 promotes hyperinflammation due to abnormal heme oxygenase-1 localization in lipopolysaccharide-challenged macrophages with dysfunctional cystic fibrosis transmembrane conductance regulator. Journal of Immunology (Baltimore, Md. : 1950). 190: 5196-206. PMID 23606537 DOI: 10.4049/Jimmunol.1201607  0.388
2012 Fields RJ, Cheng CJ, Quijano E, Weller C, Kristofik N, Duong N, Hoimes C, Egan ME, Saltzman WM. Surface modified poly(β amino ester)-containing nanoparticles for plasmid DNA delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 164: 41-8. PMID 23041278 DOI: 10.1016/J.Jconrel.2012.09.020  0.577
2012 Kravtsov DV, Caputo C, Collaco A, Hoekstra N, Egan ME, Mooseker MS, Ameen NA. Myosin Ia is required for CFTR brush border membrane trafficking and ion transport in the mouse small intestine. Traffic (Copenhagen, Denmark). 13: 1072-82. PMID 22510086 DOI: 10.1111/J.1600-0854.2012.01368.X  0.323
2011 Shenoy A, Kopic S, Murek M, Caputo C, Geibel JP, Egan ME. Calcium-modulated chloride pathways contribute to chloride flux in murine cystic fibrosis-affected macrophages. Pediatric Research. 70: 447-52. PMID 21796019 DOI: 10.1203/Pdr.0B013E31822F2448  0.385
2011 Bruscia EM, Zhang PX, Satoh A, Caputo C, Medzhitov R, Shenoy A, Egan ME, Krause DS. Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis. Journal of Immunology (Baltimore, Md. : 1950). 186: 6990-8. PMID 21593379 DOI: 10.4049/Jimmunol.1100396  0.362
2010 Lu M, Dong K, Egan ME, Giebisch GH, Boulpaep EL, Hebert SC. Mouse cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct. Proceedings of the National Academy of Sciences of the United States of America. 107: 6082-7. PMID 20231442 DOI: 10.1073/Pnas.0902661107  0.325
2010 Cartiera MS, Ferreira EC, Caputo C, Egan ME, Caplan MJ, Saltzman WM. Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin. Molecular Pharmaceutics. 7: 86-93. PMID 19886674 DOI: 10.1021/Mp900138A  0.632
2009 Bruscia EM, Zhang PX, Ferreira E, Caputo C, Emerson JW, Tuck D, Krause DS, Egan ME. Macrophages directly contribute to the exaggerated inflammatory response in cystic fibrosis transmembrane conductance regulator-/- mice. American Journal of Respiratory Cell and Molecular Biology. 40: 295-304. PMID 18776130 DOI: 10.1165/Rcmb.2008-0170Oc  0.347
2009 Egan ME. How useful are cystic fibrosis mouse models? Drug Discovery Today: Disease Models. 6: 35-41. DOI: 10.1016/J.Ddmod.2009.03.009  0.405
2008 Weiner SA, Caputo C, Bruscia E, Ferreira EC, Price JE, Krause DS, Egan ME. Rectal potential difference and the functional expression of CFTR in the gastrointestinal epithelia in cystic fibrosis mouse models. Pediatric Research. 63: 73-8. PMID 18043508 DOI: 10.1203/Pdr.0B013E31815B4Bc6  0.433
2007 Sidani SM, Kirchhoff P, Socrates T, Stelter L, Ferreira E, Caputo C, Roberts KE, Bell RL, Egan ME, Geibel JP. DeltaF508 mutation results in impaired gastric acid secretion. The Journal of Biological Chemistry. 282: 6068-74. PMID 17178714 DOI: 10.1074/Jbc.M608427200  0.34
2006 Bruscia EM, Ziegler EC, Price JE, Weiner S, Egan ME, Krause DS. Engraftment of donor-derived epithelial cells in multiple organs following bone marrow transplantation into newborn mice. Stem Cells (Dayton, Ohio). 24: 2299-308. PMID 16794262 DOI: 10.1634/Stemcells.2006-0166  0.32
2006 Bruscia EM, Price JE, Cheng EC, Weiner S, Caputo C, Ferreira EC, Egan ME, Krause DS. Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation. Proceedings of the National Academy of Sciences of the United States of America. 103: 2965-70. PMID 16481627 DOI: 10.1073/Pnas.0510758103  0.353
2006 Lu M, Leng Q, Egan ME, Caplan MJ, Boulpaep EL, Giebisch GH, Hebert SC. CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney. The Journal of Clinical Investigation. 116: 797-807. PMID 16470247 DOI: 10.1172/Jci26961  0.329
2004 Egan ME, Pearson M, Weiner SA, Rajendran V, Rubin D, Glöckner-Pagel J, Canny S, Du K, Lukacs GL, Caplan MJ. Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects. Science (New York, N.Y.). 304: 600-2. PMID 15105504 DOI: 10.1126/Science.1093941  0.446
2002 Egan ME, Glöckner-Pagel J, Ambrose C, Cahill PA, Pappoe L, Balamuth N, Cho E, Canny S, Wagner CA, Geibel J, Caplan MJ. Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells. Nature Medicine. 8: 485-92. PMID 11984593 DOI: 10.1038/Nm0502-485  0.351
2001 Wagner CA, Ott M, Klingel K, Beck S, Melzig J, Friedrich B, Wild KN, Bröer S, Moschen I, Albers A, Waldegger S, Tümmler B, Egan ME, Geibel JP, Kandolf R, et al. Effects of the serine/threonine kinase SGK1 on the epithelial Na(+) channel (ENaC) and CFTR: implications for cystic fibrosis. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 11: 209-18. PMID 11509829 DOI: 10.1159/000051935  0.413
2000 Cahill P, Nason MW, Ambrose C, Yao TY, Thomas P, Egan ME. Identification of the cystic fibrosis transmembrane conductance regulator domains that are important for interactions with ROMK2. The Journal of Biological Chemistry. 275: 16697-701. PMID 10748197 DOI: 10.1074/Jbc.M910205199  0.304
1999 Weyler RT, Yurko-Mauro KA, Rubenstein R, Kollen WJ, Reenstra W, Altschuler SM, Egan M, Mulberg AE. CFTR is functionally active in GnRH-expressing GT1-7 hypothalamic neurons. The American Journal of Physiology. 277: C563-71. PMID 10484343 DOI: 10.1152/Ajpcell.1999.277.3.C563  0.37
1999 Schwiebert EM, Benos DJ, Egan ME, Stutts MJ, Guggino WB. CFTR is a conductance regulator as well as a chloride channel. Physiological Reviews. 79: S145-66. PMID 9922379 DOI: 10.1152/Physrev.1999.79.1.S145  0.368
1998 Schwiebert EM, Egan ME, Guggino WB. Assays of dynamics, mechanisms, and regulation of ATP transport and release: implications for study of ABC transporter function. Methods in Enzymology. 292: 664-75. PMID 9711590 DOI: 10.1016/S0076-6879(98)92051-1  0.307
1998 Schwiebert EM, Morales MM, Devidas S, Egan ME, Guggino WB. Chloride channel and chloride conductance regulator domains of CFTR, the cystic fibrosis transmembrane conductance regulator. Proceedings of the National Academy of Sciences of the United States of America. 95: 2674-9. PMID 9482946 DOI: 10.1073/Pnas.95.5.2674  0.348
1997 McNicholas CM, Nason MW, Guggino WB, Schwiebert EM, Hebert SC, Giebisch G, Egan ME. A functional CFTR-NBF1 is required for ROMK2-CFTR interaction. The American Journal of Physiology. 273: F843-8. PMID 9374850 DOI: 10.1152/Ajprenal.1997.273.5.F843  0.338
1997 Rubenstein RC, Egan ME, Zeitlin PL. In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR. The Journal of Clinical Investigation. 100: 2457-65. PMID 9366560 DOI: 10.1172/Jci119788  0.385
1996 McNicholas CM, Guggino WB, Schwiebert EM, Hebert SC, Giebisch G, Egan ME. Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator. Proceedings of the National Academy of Sciences of the United States of America. 93: 8083-8. PMID 8755607 DOI: 10.1073/Pnas.93.15.8083  0.32
1995 Egan ME, Schwiebert EM, Guggino WB. Differential expression of ORCC and CFTR induced by low temperature in CF airway epithelial cells. The American Journal of Physiology. 268: C243-51. PMID 7530908 DOI: 10.1152/Ajpcell.1995.268.1.C243  0.4
Show low-probability matches.