Syed Haider - Publications

Affiliations: 
University of Oxford, Oxford, United Kingdom 

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Alexander J, Schipper K, Nash S, Brough R, Kemp H, Iacovacci J, Isacke C, Natrajan R, Sawyer E, Lord CJ, Haider S. Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer. British Journal of Cancer. PMID 38600325 DOI: 10.1038/s41416-024-02679-7  0.359
2023 Perkins DW, Steiner I, Haider S, Robertson D, Buus R, O'Leary L, Isacke CM. Therapy-induced normal tissue damage promotes breast cancer metastasis. Iscience. 27: 108503. PMID 38161426 DOI: 10.1016/j.isci.2023.108503  0.347
2023 Fitzpatrick A, Iravani M, Mills A, Vicente D, Alaguthurai T, Roxanis I, Turner NC, Haider S, Tutt ANJ, Isacke CM. Genomic profiling and pre-clinical modelling of breast cancer leptomeningeal metastasis reveals acquisition of a lobular-like phenotype. Nature Communications. 14: 7408. PMID 37973922 DOI: 10.1038/s41467-023-43242-x  0.341
2023 Mehanna H, Rapozo D, von Zeidler SV, Harrington KJ, Winter SC, Hartley A, Nankivell P, Schache AG, Sloan P, Odell EW, Thavaraj S, Hunter KD, Shah KA, Thomas GJ, Long A, ... ... Haider S, et al. Developing and validating a multivariable prognostic-predictive classifier for treatment escalation of oropharyngeal squamous cell carcinoma: the PREDICTR-OPC study. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37870417 DOI: 10.1158/1078-0432.CCR-23-1013  0.51
2023 Soosainathan A, Iravani M, El-Botty R, Alexander J, Sourd L, Morisset L, Painsec P, Orha R, Nikitorowicz-Buniak J, Pancholi S, Haider S, Dowsett M, Marangoni E, Martin LA, Isacke CM. Targeting transcriptional regulation with a CDK9 inhibitor suppresses growth of endocrine- and palbociclib-resistant ER+ breast cancers. Cancer Research. PMID 37801608 DOI: 10.1158/0008-5472.CAN-23-0650  0.329
2023 Thakur S, Haider S, Natrajan R. Implications of tumour heterogeneity on cancer evolution and therapy resistance: lessons from breast cancer. The Journal of Pathology. PMID 37587096 DOI: 10.1002/path.6158  0.408
2023 Tovey H, Sipos O, Parker JS, Hoadley KA, Quist J, Kernaghan S, Kilburn L, Salgado R, Loi S, Kennedy RD, Roxanis I, Gazinska P, Pinder SE, Bliss J, Perou CM, ... Haider S, et al. Integrated Multimodal Analyses of DNA Damage Response and Immune Markers as Predictors of Response in Metastatic Triple-Negative Breast Cancer in the TNT Trial (NCT00532727). Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. OF1-OF15. PMID 37574209 DOI: 10.1158/1078-0432.CCR-23-0370  0.313
2023 Turrell FK, Orha R, Guppy NJ, Gillespie A, Guelbert M, Starling C, Haider S, Isacke CM. Age-associated microenvironmental changes highlight the role of PDGF-C in ER breast cancer metastatic relapse. Nature Cancer. PMID 36914817 DOI: 10.1038/s43018-023-00525-y  0.338
2022 Llorca-Cardenosa MJ, Aronson LI, Krastev DB, Nieminuszczy J, Alexander J, Song F, Dylewska M, Broderick R, Brough R, Zimmermann A, Zenke FT, Gurel B, Riisnaes R, Ferreira A, Roumeliotis T, ... ... Haider S, et al. SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance. Cancer Research. OF1-OF12. PMID 36273494 DOI: 10.1158/0008-5472.CAN-21-4339  0.308
2022 Gazinska P, Milton C, Iacovacci J, Ward J, Buus R, Alaguthurai T, Graham R, Akarca A, Lips E, Naidoo K, Wesseling J, Marafioti T, Cheang M, Gillett C, Wu Y, ... ... Haider S, et al. Dynamic Changes in the NK-, Neutrophil-, and B-cell Immunophenotypes Relevant in High Metastatic Risk Post Neoadjuvant Chemotherapy-Resistant Early Breast Cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. OF1-OF15. PMID 36161312 DOI: 10.1158/1078-0432.CCR-22-0543  0.386
2022 Zois CE, Hendriks AM, Haider S, Pires E, Bridges E, Kalamida D, Voukantsis D, Lagerholm BC, Fehrmann RSN, den Dunnen WFA, Tarasov AI, Baba O, Morris J, Buffa FM, McCullagh JSO, et al. Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation. Cell Death & Disease. 13: 573. PMID 35764612 DOI: 10.1038/s41419-022-05005-2  0.447
2022 Jenkins L, Jungwirth U, Avgustinova A, Iravani M, Mills AP, Haider S, Harper J, Isacke CM. Cancer-associated fibroblasts suppress CD8+ T cell infiltration and confer resistance to immune checkpoint blockade. Cancer Research. PMID 35749591 DOI: 10.1158/0008-5472.CAN-21-4141  0.303
2022 Gómez-Cuadrado L, Bullock E, Mabruk Z, Zhao H, Souleimanova M, Noer PR, Turnbull AK, Oxvig C, Bertos N, Byron A, Dixon JM, Park M, Haider S, Natrajan R, Sims AH, et al. Characterisation of the Stromal Microenvironment in Lobular Breast Cancer. Cancers. 14. PMID 35205651 DOI: 10.3390/cancers14040904  0.352
2022 Schilling K, Harris AL, Halliday AN, Schofield CJ, Sheldon H, Haider S, Larner F. Investigations on Zinc Isotope Fractionation in Breast Cancer Tissue Using Cell Culture Uptake-Efflux Experiments. Frontiers in Medicine. 8: 746532. PMID 35127740 DOI: 10.3389/fmed.2021.746532  0.489
2021 Fitzpatrick A, Iravani M, Mills A, Childs L, Alaguthurai T, Clifford A, Garcia-Murillas I, Van Laere S, Dirix L, Harries M, Okines A, Turner NC, Haider S, Tutt ANJ, Isacke CM. Assessing CSF ctDNA to improve diagnostic accuracy and therapeutic monitoring in breast cancer leptomeningeal metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34921020 DOI: 10.1158/1078-0432.CCR-21-3017  0.315
2021 Romualdo Cardoso S, Gillespie A, Haider S, Fletcher O. Functional annotation of breast cancer risk loci: current progress and future directions. British Journal of Cancer. PMID 34741135 DOI: 10.1038/s41416-021-01612-6  0.302
2021 Sheldon H, Alexander J, Bridges E, Moreira L, Reilly S, Ang KH, Wang D, Lin S, Haider S, Banham AH, Harris AL. ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype. International Journal of Molecular Sciences. 22. PMID 34681953 DOI: 10.3390/ijms222011293  0.764
2021 Goedegebuure RSA, Kleibeuker EA, Buffa FM, Castricum KCM, Haider S, Schulkens IA, Ten Kroode L, van den Berg J, Jacobs MAJM, van Berkel AM, van Grieken NCT, Derks S, Slotman BJ, Verheul HMW, Harris AL, et al. Interferon- and STING-independent induction of type I interferon stimulated genes during fractionated irradiation. Journal of Experimental & Clinical Cancer Research : Cr. 40: 161. PMID 33964942 DOI: 10.1186/s13046-021-01962-2  0.747
2021 Peck B, Bland P, Mavrommati I, Muirhead G, Cottom H, Wai PT, Maguire SL, Barker HE, Morrison E, Kriplani D, Yu L, Gibson A, Falgari G, Brennan K, Farnie G, ... ... Haider S, et al. 3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer. Cancer Research. PMID 33509944 DOI: 10.1158/0008-5472.CAN-20-1822  0.367
2020 Morotti M, Zois CE, El-Ansari R, Craze ML, Rakha EA, Fan SJ, Valli A, Haider S, Goberdhan DCI, Green AR, Harris AL. Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer. British Journal of Cancer. PMID 33028955 DOI: 10.1038/s41416-020-01113-y  0.802
2020 Oliemuller E, Newman R, Tsang SM, Foo S, Muirhead G, Noor F, Haider S, Aurrekoetxea-Rodríguez I, Vivanco MD, Howard BA. SOX11 promotes epithelial/mesenchymal hybrid state and alters tropism of invasive breast cancer cells. Elife. 9. PMID 32909943 DOI: 10.7554/eLife.58374  0.36
2020 Yeow ZY, Lambrus BG, Marlow R, Zhan KH, Durin MA, Evans LT, Scott PM, Phan T, Park E, Ruiz LA, Moralli D, Knight EG, Badder LM, Novo D, Haider S, et al. Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer. Nature. PMID 32908313 DOI: 10.1038/S41586-020-2690-1  0.391
2019 Lord SR, Collins JM, Cheng WC, Haider S, Wigfield S, Gaude E, Fielding BA, Pinnick KE, Harjes U, Segaran A, Jha P, Hoefler G, Pollak MN, Thompson AM, Roy PG, et al. Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin. British Journal of Cancer. PMID 31819193 DOI: 10.1038/s41416-019-0665-5  0.782
2019 Favara DM, Zois CE, Haider S, Pires E, Sheldon H, McCullagh J, Banham AH, Harris AL. ADGRL4/ELTD1 Silencing in Endothelial Cells Induces ACLY and SLC25A1 and Alters the Cellular Metabolic Profile. Metabolites. 9. PMID 31775252 DOI: 10.3390/metabo9120287  0.773
2019 Fox NS, Haider S, Harris AL, Boutros PC. Landscape of transcriptomic interactions between breast cancer and its microenvironment. Nature Communications. 10: 3116. PMID 31308365 DOI: 10.1038/s41467-019-10929-z  0.475
2019 Morotti M, Bridges E, Valli A, Choudhry H, Sheldon H, Wigfield S, Gray N, Zois CE, Grimm F, Jones D, Teoh EJ, Cheng WC, Lord S, Anastasiou D, Haider S, et al. Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 31152137 DOI: 10.1073/Pnas.1818521116  0.751
2019 Valli A, Morotti M, Zois CE, Albers PK, Soga T, Feldinger K, Fischer R, Frejno M, McIntyre A, Bridges E, Haider S, Buffa FM, Baban D, Rodriguez M, Yanes O, et al. Adaptation to HIF1α deletion in hypoxic cancer cells by upregulation of GLUT14 and creatine metabolism. Molecular Cancer Research : McR. PMID 30885992 DOI: 10.1158/1541-7786.MCR-18-0315  0.749
2018 Chabanon RM, Muirhead G, Krastev DB, Adam J, Morel D, Garrido M, Lamb A, Hénon C, Dorvault N, Rouanne M, Marlow R, Bajrami I, Cardeñosa ML, Konde A, Besse B, ... ... Haider S, et al. PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer. The Journal of Clinical Investigation. PMID 30589644 DOI: 10.1172/JCI123319  0.333
2018 Jones DT, Valli A, Haider S, Zhang Q, Smethurst EA, Schug ZT, Peck B, Aboagye EO, Critchlow SE, Schulze A, Gottlieb E, Wakelam MJO, Harris AL. 3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers. Molecular Cancer Therapeutics. 18: 376-388. PMID 30478149 DOI: 10.1158/1535-7163.MCT-17-0857  0.769
2018 Lord SR, Cheng WC, Liu D, Gaude E, Haider S, Metcalf T, Patel N, Teoh EJ, Gleeson F, Bradley K, Wigfield S, Zois C, McGowan DR, Ah-See ML, Thompson AM, et al. Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer. Cell Metabolism. PMID 30244975 DOI: 10.1016/J.Cmet.2018.08.021  0.784
2018 Brough R, Gulati A, Haider S, Kumar R, Campbell J, Knudsen E, Pettitt SJ, Ryan CJ, Lord CJ. Identification of highly penetrant Rb-related synthetic lethal interactions in triple negative breast cancer. Oncogene. PMID 29915391 DOI: 10.1038/s41388-018-0368-z  0.33
2018 Yang L, Roberts D, Takhar M, Erho N, Bibby BAS, Thiruthaneeswaran N, Bhandari V, Cheng WC, Haider S, McCorry AMB, McArt D, Jain S, Alshalalfa M, Ross A, Schaffer E, et al. Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer. Ebiomedicine. PMID 29729848 DOI: 10.1016/J.Ebiom.2018.04.019  0.428
2018 Baxter JS, Leavy OC, Dryden NH, Maguire S, Johnson N, Fedele V, Simigdala N, Martin LA, Andrews S, Wingett SW, Assiotis I, Fenwick K, Chauhan R, Rust AG, Orr N, ... ... Haider S, et al. Capture Hi-C identifies putative target genes at 33 breast cancer risk loci. Nature Communications. 9: 1028. PMID 29531215 DOI: 10.1038/s41467-018-03411-9  0.312
2017 Naidoo K, Wai PT, Maguire SL, Daley F, Haider S, Kriplani D, Campbell J, Mirza H, Grigoriadis A, Tutt A, Moseley PM, Abdel-Fatah TMA, Chan SY, Madhusudan S, Rakha EA, et al. Evaluation of CDK12 Protein Expression as a Potential Novel Biomarker for DNA Damage Response Targeted Therapies in Breast Cancer. Molecular Cancer Therapeutics. PMID 29133620 DOI: 10.1158/1535-7163.MCT-17-0760  0.388
2017 Oliemuller E, Kogata N, Bland P, Kriplani D, Daley F, Haider S, Shah V, Sawyer EJ, Howard BA. SOX11 promotes invasive growth and DCIS progression. The Journal of Pathology. PMID 28707729 DOI: 10.1002/path.4939  0.302
2017 Bayani J, Yao CQ, Quintayo MA, Yan F, Haider S, D'Costa A, Brookes CL, van de Velde CJH, Hasenburg A, Kieback DG, Markopoulos C, Dirix L, Seynaeve C, Rea D, Boutros PC, et al. Molecular stratification of early breast cancer identifies drug targets to drive stratified medicine. Npj Breast Cancer. 3: 3. PMID 28649643 DOI: 10.1038/s41523-016-0003-5  0.313
2017 Ali J, Sabiha B, Jan HU, Haider SA, Khan AA, Ali SS. Genetic etiology of oral cancer. Oral Oncology. 70: 23-28. PMID 28622887 DOI: 10.1016/j.oraloncology.2017.05.004  0.307
2017 Erdal E, Haider S, Rehwinkel J, Harris AL, McHugh PJ. A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1. Genes & Development. PMID 28279982 DOI: 10.1101/gad.289769.116  0.742
2016 Lalonde E, Alkallas R, Chua ML, Fraser M, Haider S, Meng A, Zheng J, Yao CQ, Picard V, Orain M, Hovington H, Murgic J, Berlin A, Lacombe L, Bergeron A, et al. Translating a Prognostic DNA Genomic Classifier into the Clinic: Retrospective Validation in 563 Localized Prostate Tumors. European Urology. PMID 27815082 DOI: 10.1016/J.Eururo.2016.10.013  0.387
2016 Haider S, McIntyre A, van Stiphout RG, Winchester LM, Wigfield S, Harris AL, Buffa FM. Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia. Genome Biology. 17: 140. PMID 27358048 DOI: 10.1186/s13059-016-0999-8  0.789
2016 Choudhry H, Albukhari A, Morotti M, Haider S, Moralli D, Schödel J, Green C, Camps C, Buffa F, Ratcliffe P, Ragoussis I, Mole D, Harris A. Abstract A29: Hypoxia regulated long noncoding RNAs and antisense transcripts in breast cancer: Novel insights of noncoding transcriptional regulation in hypoxic microenvironment Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-A29  0.811
2016 Lord S, Liu D, Cheng W, Haider S, Gaude E, Teoh E, Patel N, Metcalf T, McGowan D, Roxanis I, Qifeng Z, Roy P, Gleeson F, Thompson A, Pollak M, et al. Metformin increases 18F-FDG flux and inhibits fatty acid oxidation at clinical doses in breast cancer: Results of a phase 0 clinical trial European Journal of Surgical Oncology (Ejso). 42: S230. DOI: 10.1016/J.Ejso.2016.07.060  0.689
2015 Choudhry H, Schodel J, Albukhari A, Haider S, Buffa F, Ratcliffe PJ, Mole DR, Ragousis I, Harris AL. Abstract P2-05-01: The non-coding transcriptome of hypoxic breast cancer: Novel insights of clinical relevant long non-coding RNA in hypoxia signalling Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P2-05-01  0.712
2014 Singleton DC, Rouhi P, Zois CE, Haider S, Li JL, Kessler BM, Cao Y, Harris AL. Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis. Oncogene. PMID 25486436 DOI: 10.1038/onc.2014.396  0.788
2014 Giatromanolaki A, Sivridis E, Mitrakas A, Kalamida D, Zois CE, Haider S, Piperidou C, Pappa A, Gatter KC, Harris AL, Koukourakis MI. Autophagy and lysosomal related protein expression patterns in human glioblastoma. Cancer Biology & Therapy. 15: 1468-78. PMID 25482944 DOI: 10.4161/15384047.2014.955719  0.567
2014 van den Beucken T, Koch E, Chu K, Rupaimoole R, Prickaerts P, Adriaens M, Voncken JW, Harris AL, Buffa FM, Haider S, Starmans MH, Yao CQ, Ivan M, Ivan C, Pecot CV, et al. Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER. Nature Communications. 5: 5203. PMID 25351418 DOI: 10.1038/Ncomms6203  0.5
2014 Pettersen EO, Ebbesen P, Gieling RG, Williams KJ, Dubois L, Lambin P, Ward C, Meehan J, Kunkler IH, Langdon SP, Ree AH, Flatmark K, Lyng H, Calzada MJ, Peso LD, ... ... Haider S, et al. Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-33. PMID 25347767 DOI: 10.3109/14756366.2014.966704  0.787
2014 Mohd Nafi SN, Generali D, Kramer-Marek G, Gijsen M, Strina C, Cappelletti M, Andreis D, Haider S, Li JL, Bridges E, Capala J, Ioannis R, Harris AL, Kong A. Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer. Oncotarget. 5: 5934-49. PMID 25153719  0.807
2014 Moore KM, Thomas GJ, Duffy SW, Warwick J, Gabe R, Chou P, Ellis IO, Green AR, Haider S, Brouilette K, Saha A, Vallath S, Bowen R, Chelala C, Eccles D, et al. Therapeutic targeting of integrin αvβ6 in breast cancer. Journal of the National Cancer Institute. 106. PMID 24974129 DOI: 10.1093/jnci/dju169  0.4
2014 Goard CA, Chan-Seng-Yue M, Mullen PJ, Quiroga AD, Wasylishen AR, Clendening JW, Sendorek DH, Haider S, Lehner R, Boutros PC, Penn LZ. Identifying molecular features that distinguish fluvastatin-sensitive breast tumor cells. Breast Cancer Research and Treatment. 143: 301-12. PMID 24337703 DOI: 10.1007/S10549-013-2800-Y  0.365
2014 Choudhry H, Schodel J, Albukhari A, Oikonomopoulos S, Haider S, Buffa F, Ragousis I, Mole DR, Harris AL. Unlocking the complexity of hypoxia non-coding transcriptome landscape of breast cancer Bmc Genomics. 15. DOI: 10.1186/1471-2164-15-S2-P40  0.674
2014 Choudhry H, Schodel J, Albukhari A, Oikonomopoulos S, Haider S, Buffa F, Ragousis I, Mole DR, Harris AL. Unlocking the complexity of hypoxia non-coding transcriptome landscape of breast cancer Bmc Genomics. 15. DOI: 10.1186/1471-2164-15-S2-O17  0.693
2014 Choudhry H, Schodel J, Albukhari A, Oikonomopoulos S, Haider S, Moralli D, Camps C, Buffa F, Ratcliffe P, Ragousis I, Mole DR, Harris AL. Unlocking the complexity of hypoxia non-coding transcriptome landscape of breast cancer Bmc Genomics. 15. DOI: 10.1186/1471-2164-15-S2-O17  0.674
2013 Awada Z, Haider S, Tfayli A, Bazarbachi A, El-Saghir NS, Salem Z, Shamseddine A, Taher A, Zgheib NK. Pharmacogenomics variation in drug metabolizing enzymes and transporters in relation to docetaxel toxicity in Lebanese breast cancer patients: paving the way for OMICs in low and middle income countries. Omics : a Journal of Integrative Biology. 17: 353-67. PMID 23758476 DOI: 10.1089/omi.2013.0019  0.303
2012 Yu M, Lin G, Arshadi N, Kalatskaya I, Xue B, Haider S, Nguyen F, Boutros PC, Elson A, Muthuswamy LB, Tonks NK, Muthuswamy SK. Expression profiling during mammary epithelial cell three-dimensional morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2-mediated transformation. Molecular and Cellular Biology. 32: 3913-24. PMID 22851698 DOI: 10.1128/Mcb.00068-12  0.378
2012 Starmans MH, Chu KC, Haider S, Nguyen F, Seigneuric R, Magagnin MG, Koritzinsky M, Kasprzyk A, Boutros PC, Wouters BG, Lambin P. The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 102: 436-43. PMID 22356756 DOI: 10.1016/J.Radonc.2012.02.002  0.367
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