Brandon C. McKinney, M.D., Ph.D. - Related publications

2010- Psychiatry University of Pittsburgh School of Medicine, Pittsburgh, PA, United States 
schizophrenia, aging, epigenetic, DNA methylation
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Kajitani GS, Brace L, Trevino-Villarreal JH, Trocha K, MacArthur MR, Vose S, Vargas D, Bronson R, Mitchell SJ, Menck CFM, Mitchell JR. Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model. Aging. 13: 22710-22731. PMID 34628368 DOI: 10.18632/aging.203617   
2021 Börner JH, Rawashdeh O, Rami A. Exacerbated Age-Related Hippocampal Alterations of Microglia Morphology, β-Amyloid and Lipofuscin Deposition and Presenilin Overexpression in -Mice. Antioxidants (Basel, Switzerland). 10. PMID 34572962 DOI: 10.3390/antiox10091330   
2021 Wen S, Ye L, Wang X, Liu D, Yang B, Man MQ. Aged and Young Mice Differentially Respond to Tape-Stripping in Epidermal Gene Expression. Experimental Dermatology. PMID 34585796 DOI: 10.1111/exd.14463   
2021 An JN, Kim H, Kim EN, Cho A, Cho Y, Choi YW, Kim JH, Yang SH, Choi BS, Lim CS, Kim YS, Kim KP, Lee JP. Effects of periostin deficiency on kidney aging and lipid metabolism. Aging. 13. PMID 34607314 DOI: 10.18632/aging.203580   
2021 Khang R, Jo A, Kang H, Kim H, Kwag E, Lee JY, Koo O, Park J, Kim HK, Jo DG, Hwang I, Ahn JY, Lee Y, Choi JY, Lee YS, et al. Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation. Scientific Reports. 11: 22745. PMID 34815492 DOI: 10.1038/s41598-021-02218-x   
2021 Ke S, Mitchell SJ, MacArthur MR, Kane AE, Sinclair DA, Venable EM, Chadaideh KS, Carmody RN, Grodstein F, Mitchell JR, Liu Y. Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice. Nutrients. 13. PMID 34579167 DOI: 10.3390/nu13093290   
2021 Tanaka Y, Onozato M, Mikami T, Kohwi-Shigematsu T, Fukushima T, Kondo M. Increased Indoleamine 2,3-Dioxygenase Levels at the Onset of Sjögren's Syndrome in SATB1-Conditional Knockout Mice. International Journal of Molecular Sciences. 22. PMID 34576286 DOI: 10.3390/ijms221810125   
2021 Li X, Tang X, Liu B, Zhang J, Zhang Y, Lv H, Liu D, Mehta JL, Wang X. LOX-1 Deletion Attenuates Myocardial Fibrosis in the Aged Mice, Particularly Those With Hypertension. Frontiers in Cardiovascular Medicine. 8: 736215. PMID 34712709 DOI: 10.3389/fcvm.2021.736215   
2021 Kim JE, Kwon EY, Han Y. Allulose Attenuated Age-Associated Sarcopenia via Regulating IGF-1 and Myostatin in Aged Mice. Molecular Nutrition & Food Research. e2100549. PMID 34710274 DOI: 10.1002/mnfr.202100549   
2021 Li R, Shen Y, Li X, Lu L, Wang Z, Sheng H, Hoffmann U, Yang W. Activation of the XBP1s/O-GlcNAcylation Pathway Improves Functional Outcome After Cardiac Arrest and Resuscitation in Young and Aged Mice. Shock (Augusta, Ga.). 56: 755-761. PMID 34652341 DOI: 10.1097/SHK.0000000000001732   
2021 Zhao Y, Liu X, Zheng Y, Liu W, Ding C. Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota. Scientific Reports. 11: 20558. PMID 34663844 DOI: 10.1038/s41598-021-00071-6   
2021 Krambs JR, Monlish DA, Gao F, Schuettpelz LG, Link DC. Microbiota Signals Suppress B Lymphopoiesis With Aging in Mice. Frontiers in Immunology. 12: 767267. PMID 34737755 DOI: 10.3389/fimmu.2021.767267   
2021 Wang Z, Yu W, Liu L, Niu J, Zhang X, Nan F, Xu L, Jiang B, Ke D, Zhu W, Tian Z, Wang Y, Wang B. Human Cytomegalovirus Immediate Early Protein 2 Protein Causes Cognitive Disorder by Damaging Synaptic Plasticity in Human Cytomegalovirus-UL122-Tg Mice. Frontiers in Aging Neuroscience. 13: 720582. PMID 34790111 DOI: 10.3389/fnagi.2021.720582   
2021 Xi W, Song N, Yan Q, Liang H, Zhang W. The analysis of the effects of Liuwei Dihuang decoction on aging-related metabolites and metabolic pathways in naturally aging mice by ultra-performance liquid chromatography quadruple time-of-light mass spectrometry. Journal of Physiology and Pharmacology : An Official Journal of the Polish Physiological Society. 72. PMID 34810292 DOI: 10.26402/jpp.2021.3.09   
2021 Tapella L, Dematteis G, Ruffinatti FA, Ponzoni L, Fiordaliso F, Corbelli A, Albanese E, Pistolato B, Pagano J, Barberis E, Marengo E, Balducci C, Forloni G, Verpelli C, Sala C, et al. Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer's disease and epilepsy and predisposes to seizures. Cell Calcium. 100: 102480. PMID 34607180 DOI: 10.1016/j.ceca.2021.102480   
2021 Castro-Torres RD, Olloquequi J, Etchetto M, Caruana P, Steele L, Leighton KM, Ureña J, Beas-Zarate C, Camins A, Verdaguer E, Auladell C. Dual and Gene Deletion in Adult Mouse Causes an Impairment of Hippocampal Immature Granule Cells. International Journal of Molecular Sciences. 22. PMID 34502457 DOI: 10.3390/ijms22179545   
2021 Aqul AA, Ramirez CM, Lopez AM, Burns DK, Repa JJ, Turley SD. Molecular markers of brain cholesterol homeostasis are unchanged despite a smaller brain mass in a mouse model of cholesteryl ester storage disease. Lipids. PMID 34618372 DOI: 10.1002/lipd.12325   
2021 Kim EJ, Ham YR, Shin JA, Jeong JY, Na KR, Lee KW, Kim JJ, Choi DE. Omega-3 Polyunsaturated Fatty Acid Attenuates Uremia-Induced Brain Damage in Mice. International Journal of Molecular Sciences. 22. PMID 34769231 DOI: 10.3390/ijms222111802   
2021 Hayward GC, Caceres D, Copeland EN, Baranowski BJ, Mohammad A, Whitley KC, Fajardo VA, MacPherson RE. Characterization of Alzheimer's Disease-like neuropathology in Duchenne's Muscular Dystrophy using the DBA/2J mdx mouse model. Febs Open Bio. PMID 34668666 DOI: 10.1002/2211-5463.13317   
2021 Yang Z, Wei ML, Dong XY. Effects of Yu Linzhu on ovarian function and oocyte mitochondria in natural aging mice. Aging. 13. PMID 34648463 DOI: 10.18632/aging.203626   
2021 Liu XL, Zhao YC, Zhu HY, Wu M, Zheng YN, Yang M, Cheng ZQ, Ding CB, Liu WC. Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice. Food & Function. PMID 34788354 DOI: 10.1039/d1fo01349a   
2021 Gao Y, Ma L, Gao F, Sun Z, Zhang Z, Li Y, Li R. Endogenous Estrogen Influences Predator Odor-Induced Impairment of Cognitive and Social Behaviors in Aromatase Gene Deficiency Mice. Behavioural Neurology. 2021: 5346507. PMID 34594430 DOI: 10.1155/2021/5346507   
2021 Gigliucci V, Teutsch J, Woodbury-Smith M, Luoni M, Busnelli M, Chini B, Banerjee A. Region-Specific KCC2 Rescue by rhIGF-1 and Oxytocin in a Mouse Model of Rett Syndrome. Cerebral Cortex (New York, N.Y. : 1991). PMID 34791112 DOI: 10.1093/cercor/bhab388   
2021 Liu Y, Masternak MM, Schneider A, Zhi X. Dwarf mice as models for reproductive ageing research. Reproductive Biomedicine Online. PMID 34794884 DOI: 10.1016/j.rbmo.2021.09.016   
2021 Bony BA, Tarudji AW, Miller HA, Gowrikumar S, Roy S, Curtis ET, Gee CC, Vecchio A, Dhawan P, Kievit FM. Claudin-1-Targeted Nanoparticles for Delivery to Aging-Induced Alterations in the Blood-Brain Barrier. Acs Nano. PMID 34748307 DOI: 10.1021/acsnano.1c08432   
2021 Chen J, Fan ZX, Zhu DC, Guo YL, Ye K, Dai D, Guo Z, Hu ZQ, Miao Y, Qu Q. Emerging Role of Dermal White Adipose Tissue in Modulating Hair Follicle Development During Aging. Frontiers in Cell and Developmental Biology. 9: 728188. PMID 34722509 DOI: 10.3389/fcell.2021.728188   
2021 Mitchell J, Kim SJ, Howe C, Lee S, Her JY, Patel M, Kim G, Lee J, Im E, Rhee SH. Chronic intestinal inflammation suppresses brain activity by inducing neuroinflammation in mice. The American Journal of Pathology. PMID 34619134 DOI: 10.1016/j.ajpath.2021.09.006   
2021 Adayev T, LaFauci G, Xu W, Dobkin C, Kascsak R, Brown WT, Goodman JH. Development of a Quantitative FMRP Assay for Mouse Tissue Applications. Genes. 12. PMID 34680911 DOI: 10.3390/genes12101516   
2021 Aires R, Porto ML, de Assis LM, Pereira PAN, Carvalho GR, Côco LZ, Vasquez EC, Pereira TMC, Campagnaro BP, Meyrelles SS. DNA damage and aging on hematopoietic stem cells: Impact of oxidative stress in ApoE/ mice. Experimental Gerontology. 156: 111607. PMID 34715304 DOI: 10.1016/j.exger.2021.111607   
2021 Yeh CH, Chou YJ, Chu TK, Tsai TF. Rejuvenating the Aging Heart by Enhancing the Expression of the Prolongevity Gene. International Journal of Molecular Sciences. 22. PMID 34768917 DOI: 10.3390/ijms222111487   
2021 Inoue M, Nakahama T, Yamasaki R, Shibuya T, Kim JI, Todo H, Xing Y, Kato Y, Morii E, Kawahara Y. An Aicardi-Goutières Syndrome-Causative Point Mutation in Gene Invokes Multiorgan Inflammation and Late-Onset Encephalopathy in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 34772697 DOI: 10.4049/jimmunol.2100526   
2021 Wang Y, Sun Z, Du S, Wei H, Li X, Li X, Shen J, Chen X, Cai Z. The increase of α-synuclein and alterations of dynein in A53T transgenic and aging mouse. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 34810061 DOI: 10.1016/j.jocn.2021.11.002   
2021 Liang T, Xu Q, Zhang H, Wang S, Diekwisch TGH, Qin C, Lu Y. Enamel Defects Associated With Dentin Sialophosphoprotein Mutation in Mice. Frontiers in Physiology. 12: 724098. PMID 34630144 DOI: 10.3389/fphys.2021.724098   
2021 Ling Q, Rioux M, Hu Y, Lee M, Gray SJ. Adeno-associated viral vector serotype 9-based gene replacement therapy for -related Leigh syndrome. Molecular Therapy. Methods & Clinical Development. 23: 158-168. PMID 34703839 DOI: 10.1016/j.omtm.2021.09.001   
2021 Thapa D, Valente JS, Barrett B, Smith MJ, Argunhan F, Lee SY, Nikitochkina S, Kodji X, Brain SD. Dysfunctional TRPM8 signalling in the vascular response to environmental cold in ageing. Elife. 10. PMID 34726597 DOI: 10.7554/eLife.70153   
2021 F Martins ML, Loos NHC, Mucuk S, de Jong D, Lebre MC, Rosing H, Tibben M, Beijnen JH, Schinkel AH. P-Glycoprotein (ABCB1/MDR1) Controls Brain Penetration and Intestinal Disposition of the PARP1/2 Inhibitor Niraparib. Molecular Pharmaceutics. PMID 34730366 DOI: 10.1021/acs.molpharmaceut.1c00553   
2021 Li Y, Tai HC, Sladojevic N, Kim HH, Liao JK. Vascular Stiffening Mediated by Rho-Associated Coiled-Coil Containing Kinase Isoforms. Journal of the American Heart Association. e022568. PMID 34612053 DOI: 10.1161/JAHA.121.022568   
2021 Mittelstaedt RA, Dad A, Pearce MG, Heflich RH, Cao X. Effect of life stage and target tissue on dose-response assessment of ethyl methane sulfonate-induced genotoxicity. Environmental and Molecular Mutagenesis. PMID 34647641 DOI: 10.1002/em.22465   
2021 Maiolati M, Tarmati V, Latagliata C, Cabib S, Orsini C. Opposite genotype-specific effects of serotoninergic treatments on Pavlovian Conditioned Approach in mice of two inbred strains C57 BL/6J and DBA/2J. Behavioural Pharmacology. 32: 392-403. PMID 33709985 DOI: 10.1097/FBP.0000000000000629   
2021 Dhahbi JM, Chen JW, Bhupathy S, Atamna H, Cavalcante MB, Saccon TD, Nunes ADC, Mason JB, Schneider A, Masternak MM. Specific PIWI-Interacting RNAs and Related Small Noncoding RNAs Are Associated With Ovarian Aging in Ames Dwarf (df/df) Mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 76: 1561-1570. PMID 34387333 DOI: 10.1093/gerona/glab113   
2021 Sugimoto K, Liu J, Li M, Song Y, Zhang C, Zhai Z, Gao Y. Neuroprotective Effects of Shenqi Fuzheng Injection in a Transgenic SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis. Frontiers in Pharmacology. 12: 701886. PMID 34737697 DOI: 10.3389/fphar.2021.701886   
2021 Karlsen TR, Kong XY, Holm S, Quiles-Jiménez A, Dahl TB, Yang K, Sagen EL, Skarpengland T, S Øgaard JD, Holm K, Vestad B, Olsen MB, Aukrust P, Bjørås M, Hov JR, et al. NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype. Scientific Reports. 11: 19749. PMID 34611194 DOI: 10.1038/s41598-021-98820-0   
2021 Mohammed S, Thadathil N, Selvarani R, Nicklas EH, Wang D, Miller BF, Richardson A, Deepa SS. Necroptosis contributes to chronic inflammation and fibrosis in aging liver. Aging Cell. e13512. PMID 34761505 DOI: 10.1111/acel.13512   
2021 Qian Y, Berryman DE, Basu R, List EO, Okada S, Young JA, Jensen EA, Bell SRC, Kulkarni P, Duran-Ortiz S, Mora-Criollo P, Mathes SC, Brittain AL, Buchman M, Davis E, et al. Mice with gene alterations in the GH and IGF family. Pituitary. PMID 34797529 DOI: 10.1007/s11102-021-01191-y   
2021 Kaucsár T, Róka B, Tod P, Do PT, Hegedűs Z, Szénási G, Hamar P. Divergent regulation of lncRNA expression by ischemia in adult and aging mice. Geroscience. PMID 34697716 DOI: 10.1007/s11357-021-00460-9   
2021 Sproull M, Hayes J, Ishiniwa H, Nanba K, Shankavaram U, Camphausen K, Johnson TE. Proteomic Biomarker Analysis of Serum from Japanese Field Mice (Apodemus Speciosus) Collected within the Fukushima Difficult-to-return Zone. Health Physics. PMID 34618712 DOI: 10.1097/HP.0000000000001467   
2021 Li C, Li J, Tao H, Shan J, Liu F, Deng X, Lin Y, Lin X, Fu L, Wang B, Bi Y. Differential hippocampal protein expression between normal mice and mice with the perioperative neurocognitive disorder: a proteomic analysis. European Journal of Medical Research. 26: 130. PMID 34732255 DOI: 10.1186/s40001-021-00599-3   
2021 Wang Y, Mao J, Li L, Xiao B, Ruan Z, Liu Y, Zhang G, Wang D, Mi JQ, Fang C, Xi X, Shi X, Wang J. Characteristics of the Thrombus Formation in Transgenic Mice with Platelet-Targeted Factor VIII Expression. Thrombosis and Haemostasis. PMID 34587639 DOI: 10.1055/s-0041-1735531   
2021 Marbach-Breitrück E, Rohwer N, Infante-Duarte C, Romero-Suarez S, Labuz D, Machelska H, Kutzner L, Schebb NH, Rothe M, Reddanna P, Weylandt KH, Wieler LH, Heydeck D, Kuhn H. Knock-In Mice Expressing a 15-Lipoxygenating Alox5 Mutant Respond Differently to Experimental Inflammation Than Reported Mice. Metabolites. 11. PMID 34677413 DOI: 10.3390/metabo11100698   
2021 Ma X, Chen L, Song N, Qu L, Wang J, Xie J. Blood-Derived α-Synuclein Aggregated in the Substantia Nigra of Parabiotic Mice. Biomolecules. 11. PMID 34572500 DOI: 10.3390/biom11091287