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Maureen McKeague, PhD - Publications

Affiliations: 
2007-2012 Chemistry Carleton University, Ottawa, Canada 
 2012-2016 Bioengineering Stanford University, Palo Alto, CA 
 2016-2018 Health Sciences and Technology Eidgenössische Technische Hochschule Zürich, Zürich, ZH, Switzerland 
Area:
toxicology, DNA damage, aptamers, in vitro selection, small molecules, metabolic engineering, natural products, RNA devices, mycotoxins, biosensors
Website:
http://openwetware.org/wiki/User:Maureen_McKeague
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jiang Y, Mingard C, Huber SM, Takhaveev V, McKeague M, Kizaki S, Schneider M, Ziegler N, Hürlimann V, Hoeng J, Sierro N, Ivanov NV, Sturla SJ. Quantification and Mapping of Alkylation in the Human Genome Reveal Single Nucleotide Resolution Precursors of Mutational Signatures. Acs Central Science. 9: 362-372. PMID 36968528 DOI: 10.1021/acscentsci.2c01100  0.5
2020 Mingard C, Wu J, McKeague M, Sturla SJ. Next-generation DNA damage sequencing. Chemical Society Reviews. PMID 32968744 DOI: 10.1039/d0cs00647e  0.503
2020 Oteng EK, Gu W, McKeague M. High-efficiency enrichment enables identification of aptamers to circulating Plasmodium falciparum-infected erythrocytes. Scientific Reports. 10: 9706. PMID 32546848 DOI: 10.1038/S41598-020-66537-1  0.368
2019 Xiang JS, Kaplan M, Dykstra P, Hinks M, McKeague M, Smolke CD. Massively parallel RNA device engineering in mammalian cells with RNA-Seq. Nature Communications. 10: 4327. PMID 31548547 DOI: 10.1038/S41467-019-12334-Y  0.639
2019 Smith M, McKeague M, DeRosa MC. Synthesis, transfer, and characterization of core-shell gold-coated magnetic nanoparticles. Methodsx. 6: 333-354. PMID 30859070 DOI: 10.1016/J.Mex.2019.02.006  0.527
2018 Kraus A, McKeague M, Seiwert N, Nagel G, Geisen SM, Ziegler N, Trantakis IA, Kaina B, Thomas AD, Sturla SJ, Fahrer J. Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O-methylguanine in vivo. Archives of Toxicology. PMID 30446773 DOI: 10.1007/S00204-018-2355-0  0.505
2018 McKeague M, Otto C, Räz MH, Angelov T, Sturla SJ. Base-pairing partner modulates alkylguanine alkyltransferase. Acs Chemical Biology. PMID 30040894 DOI: 10.1021/Acschembio.8B00446  0.539
2018 Wu J, Mckeague M, Sturla SJ. Nucleotide-resolution genome-wide mapping of oxidative DNA damage by click-code-seq. Journal of the American Chemical Society. PMID 29944356 DOI: 10.1021/Jacs.8B03715  0.549
2018 Dahlmann HA, Berger FD, Kung RW, Wyss LA, Gubler I, McKeague M, Wetmore SD, Sturla SJ. Fluorescent Nucleobase Analogues with Extended Pi Surfaces Stabilize DNA Duplexes Containing O 6 -Alkylguanine Adducts Helvetica Chimica Acta. 101: e1800066. DOI: 10.1002/Hlca.201800066  0.522
2017 Ruscito A, McConnell EM, Koudrina A, Velu R, Mattice C, Hunt V, McKeague M, DeRosa MC. In Vitro Selection and Characterization of DNA Aptamers to a Small Molecule Target. Current Protocols in Chemical Biology. 9: 233-268. PMID 29241295 DOI: 10.1002/cpch.28  0.361
2017 Ruscito A, McConnell EM, Koudrina A, Velu R, Mattice C, Hunt V, McKeague M, DeRosa MC. In Vitro Selection and Characterization of DNA Aptamers to a Small Molecule Target. Current Protocols in Chemical Biology. 9: 233-268. PMID 29241295 DOI: 10.1002/Cpch.28  0.663
2017 McKeague M. Aptamers for DNA Damage and Repair. International Journal of Molecular Sciences. 18. PMID 29065503 DOI: 10.3390/Ijms18102212  0.332
2017 Alsaafin A, McKeague M. Functional nucleic acids as in vivo metabolite and ion biosensors. Biosensors & Bioelectronics. 94: 94-106. PMID 28262613 DOI: 10.1016/J.Bios.2017.02.030  0.326
2016 McKeague M, Velu R, De Girolamo A, Valenzano S, Pascale M, Smith M, DeRosa MC. Comparison of In-Solution Biorecognition Properties of Aptamers against Ochratoxin A. Toxins. 8. PMID 27854269 DOI: 10.3390/Toxins8110336  0.649
2016 Wang YH, McKeague M, Hsu TM, Smolke CD. Design and Construction of Generalizable RNA-Protein Hybrid Controllers by Level-Matched Genetic Signal Amplification. Cell Systems. PMID 27840078 DOI: 10.1016/J.Cels.2016.10.008  0.621
2016 McKeague M, Wang YH, Cravens A, Win MN, Smolke CD. Engineering a microbial platform for de novo biosynthesis of diverse methylxanthines. Metabolic Engineering. PMID 27519552 DOI: 10.1016/J.Ymben.2016.08.003  0.706
2016 Valenzano S, De Girolamo A, DeRosa MC, McKeague M, Schena R, Catucci L, Pascale M. Screening and identification of DNA aptamers to tyramine using in vitro selection and high-throughput sequencing. Acs Combinatorial Science. PMID 27057927 DOI: 10.1021/Acscombsci.5B00163  0.682
2016 McKeague M, Wong RS, Smolke CD. Opportunities in the design and application of RNA for gene expression control. Nucleic Acids Research. PMID 26969733 DOI: 10.1093/Nar/Gkw151  0.673
2015 McKeague M, McConnell EM, Cruz-Toledo J, Bernard ED, Pach A, Mastronardi E, Zhang X, Beking M, Francis T, Giamberardino A, Cabecinha A, Ruscito A, Aranda-Rodriguez R, Dumontier M, DeRosa MC. Analysis of In Vitro Aptamer Selection Parameters. Journal of Molecular Evolution. PMID 26530075 DOI: 10.1007/S00239-015-9708-6  0.629
2015 McKeague M, Wang YH, Smolke CD. In Vitro Screening and in Silico Modeling of RNA-Based Gene Expression Control. Acs Chemical Biology. PMID 26359915 DOI: 10.1021/Acschembio.5B00518  0.675
2015 Frost NR, McKeague M, Falcioni D, DeRosa MC. An in solution assay for interrogation of affinity and rational minimer design for small molecule-binding aptamers. The Analyst. 140: 6643-51. PMID 26336657 DOI: 10.1039/C5An01075F  0.656
2015 McKeague M, De Girolamo A, Valenzano S, Pascale M, Ruscito A, Velu R, Frost NR, Hill K, Smith M, McConnell EM, DeRosa MC. Comprehensive Analytical Comparison of Strategies Used for Small Molecule Aptamer Evaluation. Analytical Chemistry. PMID 26192270 DOI: 10.1021/Acs.Analchem.5B02102  0.664
2014 Chang AL, McKeague M, Smolke CD. Facile characterization of aptamer kinetic and equilibrium binding properties using surface plasmon resonance. Methods in Enzymology. 549: 451-66. PMID 25432760 DOI: 10.1016/B978-0-12-801122-5.00019-2  0.668
2014 McKeague M, Velu R, Hill K, Bardóczy V, Mészáros T, DeRosa MC. Selection and characterization of a novel DNA aptamer for label-free fluorescence biosensing of ochratoxin A. Toxins. 6: 2435-52. PMID 25153252 DOI: 10.3390/Toxins6082435  0.647
2014 Chang AL, McKeague M, Liang JC, Smolke CD. Kinetic and equilibrium binding characterization of aptamers to small molecules using a label-free, sensitive, and scalable platform. Analytical Chemistry. 86: 3273-8. PMID 24548121 DOI: 10.1021/Ac5001527  0.725
2013 Mastronardi E, Mckeague M, Monreal C, DeRosa M. 139 Development and application of crop exudate specific aptamers Journal of Biomolecular Structure and Dynamics. 31: 89-89. DOI: 10.1080/07391102.2013.786381  0.619
2013 McKeague M, Foster A, Miguel Y, Giamberardino A, Verdin C, Chan JYS, Derosa MC. Development of a DNA aptamer for direct and selective homocysteine detection in human serum Rsc Advances. 3: 24415-24422. DOI: 10.1039/C3Ra43893G  0.625
2012 McKeague M, Derosa MC. Challenges and opportunities for small molecule aptamer development. Journal of Nucleic Acids. 2012: 748913. PMID 23150810 DOI: 10.1155/2012/748913  0.648
2012 Cruz-Toledo J, McKeague M, Zhang X, Giamberardino A, McConnell E, Francis T, DeRosa MC, Dumontier M. Aptamer Base: a collaborative knowledge base to describe aptamers and SELEX experiments. Database : the Journal of Biological Databases and Curation. 2012: bas006. PMID 22434840 DOI: 10.1093/Database/Bas006  0.637
2011 De Girolamo A, McKeague M, Miller JD, DeRosa MC, Visconti A. Determination of ochratoxin A in wheat after clean-up through a DNA aptamer-based solid phase extraction column. Food Chemistry. 127: 1378-84. PMID 25214141 DOI: 10.1016/J.Foodchem.2011.01.107  0.576
2010 McKeague M, Bradley CR, De Girolamo A, Visconti A, Miller JD, Derosa MC. Screening and initial binding assessment of fumonisin b(1) aptamers. International Journal of Molecular Sciences. 11: 4864-81. PMID 21614178 DOI: 10.3390/Ijms11124864  0.633
2010 Luo X, McKeague M, Pitre S, Dumontier M, Green J, Golshani A, Derosa MC, Dehne F. Computational approaches toward the design of pools for the in vitro selection of complex aptamers. Rna (New York, N.Y.). 16: 2252-62. PMID 20870801 DOI: 10.1261/Rna.2102210  0.64
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