Xiaoguang Li - Publications

Affiliations: 
2015-2021 SBP Medical Discovery Institute 

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang X, Xie J, Tan L, Lu Y, Shen N, Li J, Hu H, Li H, Li X, Cheng L. N6-methyladenosine-modified circRIMS2 mediates synaptic and memory impairments by activating GluN2B ubiquitination in Alzheimer's disease. Translational Neurodegeneration. 12: 53. PMID 38012808 DOI: 10.1186/s40035-023-00386-6  0.31
2021 Jiang L, Li X, Myers S, Huang T, Kaufman RJ. Astroglial ER protein Membralin is an essential neuroinflammation regulator. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058566. PMID 34971195 DOI: 10.1002/alz.058566  0.651
2020 Liu T, Zhu B, Liu Y, Zhang X, Yin J, Li X, Jiang L, Hodges AP, Rosenthal SB, Zhou L, Yancey J, McQuade A, Blurton-Jones M, Tanzi RE, Huang TY, et al. Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE. The Journal of Experimental Medicine. 217. PMID 32941599 DOI: 10.1084/Jem.20200474  0.744
2019 Feng Q, Luo Y, Zhang XN, Yang XF, Hong XY, Sun DS, Li XC, Hu Y, Li XG, Zhang JF, Li X, Yang Y, Wang Q, Liu GP, Wang JZ. MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration. Autophagy. PMID 31223056 DOI: 10.1080/15548627.2019.1633862  0.38
2019 Jiang LL, Zhu B, Zhao Y, Li X, Liu T, Pina-Crespo J, Zhou L, Xu W, Rodriguez MJ, Yu H, Cleveland DW, Ravits J, Da Cruz S, Long T, Huang TY, et al. Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment. The Journal of Clinical Investigation. 130. PMID 31112137 DOI: 10.1172/Jci127695  0.694
2019 Li XG, Hong XY, Wang YL, Zhang SJ, Zhang JF, Li XC, Liu YC, Sun DS, Feng Q, Ye JW, Gao Y, Ke D, Wang Q, Li HL, Ye K, et al. Tau accumulation triggers STAT1-dependent memory deficits by suppressing NMDA receptor expression. Embo Reports. PMID 31085626 DOI: 10.15252/embr.201847202  0.348
2018 Zhang Z, Li XG, Wang ZH, Song M, Yu SP, Kang SS, Liu X, Zhang Z, Xie M, Liu GP, Wang JZ, Ye K. δ-Secretase-cleaved Tau stimulates Aβ production via upregulating STAT1-BACE1 signaling in Alzheimer's disease. Molecular Psychiatry. PMID 30382187 DOI: 10.1038/s41380-018-0286-z  0.402
2018 Gao Y, Liu EJ, Wang WJ, Wang YL, Li XG, Wang X, Li SH, Zhang SJ, Li MZ, Zhou QZ, Long XB, Zhang HQ, Wang JZ. Microglia CREB-Phosphorylation Mediates Amyloid-β-Induced Neuronal Toxicity. Journal of Alzheimer's Disease : Jad. PMID 30282353 DOI: 10.3233/JAD-180286  0.367
2018 Lee CYD, Daggett A, Gu X, Jiang LL, Langfelder P, Li X, Wang N, Zhao Y, Park CS, Cooper Y, Ferando I, Mody I, Coppola G, Xu H, Yang XW. Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models. Neuron. 97: 1032-1048.e5. PMID 29518357 DOI: 10.1016/J.Neuron.2018.02.002  0.695
2018 Zhao Y, Wu X, Li X, Jiang LL, Gui X, Liu Y, Sun Y, Zhu B, Piña-Crespo JC, Zhang M, Zhang N, Chen X, Bu G, An Z, Huang TY, et al. TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function. Neuron. 97: 1023-1031.e7. PMID 29518356 DOI: 10.1016/J.Neuron.2018.01.031  0.757
2017 Zhao Y, Li X, Huang T, Jiang LL, Tan Z, Zhang M, Cheng IH, Wang X, Bu G, Zhang YW, Wang Q, Xu H. Intracellular trafficking of TREM2 is regulated by presenilin 1. Experimental & Molecular Medicine. 49: e405. PMID 29611543 DOI: 10.1038/Emm.2017.200  0.75
2017 Zhu B, Jiang L, Huang T, Zhao Y, Liu T, Zhong Y, Li X, Campos A, Pomeroy K, Masliah E, Zhang D, Xu H. ER-associated degradation regulates Alzheimer's amyloid pathology and memory function by modulating γ-secretase activity. Nature Communications. 8: 1472. PMID 29133892 DOI: 10.1038/S41467-017-01799-4  0.746
2017 Huang TY, Zhao Y, Jiang LL, Li X, Liu Y, Sun Y, Piña-Crespo JC, Zhu B, Masliah E, Willnow TE, Pasquale EB, Xu H. SORLA attenuates EphA4 signaling and amyloid β-induced neurodegeneration. The Journal of Experimental Medicine. PMID 29114064 DOI: 10.1084/Jem.20171413  0.755
2017 Zhang Z, Obianyo O, Dall E, Du Y, Fu H, Liu X, Kang SS, Song M, Yu SP, Cabrele C, Schubert M, Li X, Wang JZ, Brandstetter H, Ye K. Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease. Nature Communications. 8: 14740. PMID 28345579 DOI: 10.1038/Ncomms14740  0.386
2016 Huang TY, Zhao Y, Li X, Wang X, Tseng IC, Thompson R, Tu S, Willnow TE, Zhang YW, Xu H. SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7996-8011. PMID 27466343 DOI: 10.1523/Jneurosci.0206-16.2016  0.721
2015 Yang C, Li X, Mo Y, Liu S, Zhao L, Ma X, Fang Z, Chen J, Chen Y, Yu X, Fang S, Zhang Y, Xian S, Wang Q. β-Asarone Mitigates Amyloidosis and Downregulates RAGE in a Transgenic Mouse Model of Alzheimer's Disease. Cellular and Molecular Neurobiology. PMID 26271288 DOI: 10.1007/s10571-015-0226-2  0.396
2014 Xu ZP, Li L, Bao J, Wang ZH, Zeng J, Liu EJ, Li XG, Huang RX, Gao D, Li MZ, Zhang Y, Liu GP, Wang JZ. Magnesium protects cognitive functions and synaptic plasticity in streptozotocin-induced sporadic Alzheimer's model. Plos One. 9: e108645. PMID 25268773 DOI: 10.1371/journal.pone.0108645  0.36
2005 Luo HM, Deng H, Xiao F, Gao Q, Weng W, Zhang PF, Li XG. Down-regulation amyloid beta-protein 42 production by interfering with transcript of presenilin 1 gene with siRNA. Acta Pharmacologica Sinica. 25: 1613-8. PMID 15569405  0.301
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