| Year |
Citation |
Score |
| 2022 |
Rawat V, Banik A, Amaradhi R, Rojas A, Taval S, Nagy T, Dingledine R, Ganesh T. Pharmacological antagonism of EP2 receptor does not modify basal cardiovascular and respiratory function, blood cell counts, and bone morphology in animal models. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 147: 112646. PMID 35091236 DOI: 10.1016/j.biopha.2022.112646 |
0.751 |
|
| 2021 |
Bonilla-Jaime H, Zeleke H, Rojas A, Espinosa-Garcia C. Sleep Disruption Worsens Seizures: Neuroinflammation as a Potential Mechanistic Link. International Journal of Molecular Sciences. 22. PMID 34830412 DOI: 10.3390/ijms222212531 |
0.698 |
|
| 2021 |
Espinosa-Garcia C, Zeleke H, Rojas A. Impact of Stress on Epilepsy: Focus on Neuroinflammation-A Mini Review. International Journal of Molecular Sciences. 22. PMID 33920037 DOI: 10.3390/ijms22084061 |
0.708 |
|
| 2021 |
Rojas A, Amaradhi R, Banik A, Jiang C, Abreu-Melon J, Wang S, Dingledine R, Ganesh T. A Novel Second-Generation EP2 Receptor Antagonist Reduces Neuroinflammation and Gliosis After Status Epilepticus in Rats. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33410110 DOI: 10.1007/s13311-020-00969-5 |
0.815 |
|
| 2020 |
Rojas A, Wang J, Glover A, Dingledine R. Urethane attenuates early neuropathology of diisopropylfluorophosphate-induced status epilepticus in rats. Neurobiology of Disease. 104863. PMID 32283202 DOI: 10.1016/J.Nbd.2020.104863 |
0.624 |
|
| 2020 |
Amaradhi R, Banik A, Mohammed S, Patro V, Rojas A, Wang W, Motati DR, Dingledine R, Ganesh T. Potent, selective, water soluble, brain-permeable EP2 receptor antagonist for use in central nervous system disease models. Journal of Medicinal Chemistry. PMID 31904232 DOI: 10.1021/Acs.Jmedchem.9B01218 |
0.793 |
|
| 2019 |
Rojas A, Banik A, Chen D, Flood K, Ganesh T, Dingledine R. A novel microglia cell line expressing the human EP2 receptor. Acs Chemical Neuroscience. PMID 31469538 DOI: 10.1021/Acschemneuro.9B00311 |
0.781 |
|
| 2019 |
Manji Z, Rojas A, Wang W, Dingledine R, Varvel NH, Ganesh N. 5xFAD Mice Display Sex-Dependent Inflammatory Gene Induction During the Prodromal Stage of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31322556 DOI: 10.3233/Jad-180678 |
0.75 |
|
| 2019 |
Rojas A, Ganesh T, Wang W, Wang J, Dingledine R. A rat model of organophosphate-induced status epilepticus and the beneficial effects of EP2 receptor inhibition. Neurobiology of Disease. PMID 30818067 DOI: 10.1016/J.Nbd.2019.02.010 |
0.78 |
|
| 2018 |
Rojas A, Chen D, Ganesh T, Varvel NH, Dingledine R. The COX-2/prostanoid signaling cascades in seizure disorders. Expert Opinion On Therapeutic Targets. PMID 30484341 DOI: 10.1080/14728222.2019.1554056 |
0.802 |
|
| 2018 |
Rojas A, Wang W, Glover A, Manji Z, Fu Y, Dingledine R. Beneficial Outcome of Urethane Treatment Following Status Epilepticus in a Rat Organophosphorus Toxicity Model. Eneuro. 5. PMID 29766039 DOI: 10.1523/ENEURO.0070-18.2018 |
0.557 |
|
| 2017 |
Rojas A, Ganesh T, Walker A, Dingledine R. Ethylatropine bromide as a peripherally-restricted muscarinic antagonist. Acs Chemical Neuroscience. PMID 28044440 DOI: 10.1021/Acschemneuro.6B00334 |
0.75 |
|
| 2016 |
Rojas A, Ganesh T, Manji Z, O'neill T, Dingledine R. Inhibition of the prostaglandin E2 receptor EP2 prevents status epilepticus-induced deficits in the novel object recognition task in rats. Neuropharmacology. PMID 27477533 DOI: 10.1016/J.Neuropharm.2016.07.028 |
0.754 |
|
| 2015 |
Rojas A, Ganesh T, Lelutiu N, Gueorguieva P, Dingledine R. Inhibition of the prostaglandin EP2 receptor is neuroprotective and accelerates functional recovery in a rat model of organophosphorus induced status epilepticus. Neuropharmacology. 93: 15-27. PMID 25656476 DOI: 10.1016/J.Neuropharm.2015.01.017 |
0.777 |
|
| 2014 |
Rojas A, Gueorguieva P, Lelutiu N, Quan Y, Shaw R, Dingledine R. The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus. Neurobiology of Disease. 70: 74-89. PMID 24952362 DOI: 10.1016/J.Nbd.2014.06.004 |
0.767 |
|
| 2014 |
Rojas A, Jiang J, Ganesh T, Yang MS, Lelutiu N, Gueorguieva P, Dingledine R. Cyclooxygenase-2 in epilepsy. Epilepsia. 55: 17-25. PMID 24446952 DOI: 10.1111/Epi.12461 |
0.749 |
|
| 2013 |
Rojas A, Dingledine R. Ionotropic glutamate receptors: regulation by G-protein-coupled receptors. Molecular Pharmacology. 83: 746-52. PMID 23348498 DOI: 10.1124/Mol.112.083352 |
0.59 |
|
| 2013 |
Rojas A, Wetherington J, Shaw R, Serrano G, Swanger S, Dingledine R. Activation of group I metabotropic glutamate receptors potentiates heteromeric kainate receptors. Molecular Pharmacology. 83: 106-21. PMID 23066089 DOI: 10.1124/Mol.112.081802 |
0.789 |
|
| 2012 |
Jiang J, Ganesh T, Du Y, Quan Y, Serrano G, Qui M, Speigel I, Rojas A, Lelutiu N, Dingledine R. Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2. Proceedings of the National Academy of Sciences of the United States of America. 109: 3149-54. PMID 22323596 DOI: 10.1073/Pnas.1120195109 |
0.797 |
|
| 2011 |
Serrano GE, Lelutiu N, Rojas A, Cochi S, Shaw R, Makinson CD, Wang D, FitzGerald GA, Dingledine R. Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14850-60. PMID 22016518 DOI: 10.1523/Jneurosci.3922-11.2011 |
0.67 |
|
| 2010 |
Jiang J, Ganesh T, Du Y, Thepchatri P, Rojas A, Lewis I, Kurtkaya S, Li L, Qui M, Serrano G, Shaw R, Sun A, Dingledine R. Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor. Proceedings of the National Academy of Sciences of the United States of America. 107: 2307-12. PMID 20080612 DOI: 10.1073/Pnas.0909310107 |
0.786 |
|
| 2010 |
Mott DD, Rojas A, Fisher JL, Dingledine RJ, Benveniste M. Subunit-specific desensitization of heteromeric kainate receptors. The Journal of Physiology. 588: 683-700. PMID 20026616 DOI: 10.1113/Jphysiol.2009.185207 |
0.74 |
|
| 2008 |
Rojas A, Su J, Yang L, Lee M, Cui N, Zhang X, Fountain D, Jiang C. Modulation of the heteromeric Kir4.1-Kir5.1 channel by multiple neurotransmitters via Galphaq-coupled receptors. Journal of Cellular Physiology. 214: 84-95. PMID 17559083 DOI: 10.1002/Jcp.21169 |
0.33 |
|
| 2007 |
Shi Y, Wu Z, Cui N, Shi W, Yang Y, Zhang X, Rojas A, Ha BT, Jiang C. PKA phosphorylation of SUR2B subunit underscores vascular KATP channel activation by beta-adrenergic receptors. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R1205-14. PMID 17596331 DOI: 10.1152/Ajpregu.00337.2007 |
0.302 |
|
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