Daphne Holt - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
psychiatry, functional neuroanatomy

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Babadi B, Dokholyan K, DeTore NR, Tootell RBH, Sussman RF, Zapetis SL, Holt DJ. Arousal responses to personal space intrusions in psychotic illness: A virtual reality study. Schizophrenia Research. 274: 158-170. PMID 39305791 DOI: 10.1016/j.schres.2024.09.004  0.335
2024 Holt DJ. Personal space as a model neurobehavioral system for investigating schizophrenia. Schizophrenia Research. 267: 396-397. PMID 38640850 DOI: 10.1016/j.schres.2024.04.010  0.332
2024 Deng W, Tuominen L, Sussman R, Leathem L, Vinke LN, Holt DJ. Changes in responses of the amygdala and hippocampus during fear conditioning are associated with persecutory beliefs. Scientific Reports. 14: 8173. PMID 38589562 DOI: 10.1038/s41598-024-57746-z  0.319
2022 Eryilmaz H, Pax M, O'Neill AG, Vangel M, Diez I, Holt DJ, Camprodon JA, Sepulcre J, Roffman JL. Network hub centrality and working memory performance in schizophrenia. Schizophrenia (Heidelberg, Germany). 8: 76. PMID 36151201 DOI: 10.1038/s41537-022-00288-y  0.328
2022 Zapetis SL, Nasiriavanaki Z, Luther L, Holt DJ. Neural Correlates of Variation in Personal Space and Social Functioning in Schizophrenia and Healthy Individuals. Schizophrenia Bulletin. PMID 35661903 DOI: 10.1093/schbul/sbac052  0.41
2022 Di Biase MA, Geaghan MP, Reay WR, Seidlitz J, Weickert CS, Pébay A, Green MJ, Quidé Y, Atkins JR, Coleman MJ, Bouix S, Knyazhanskaya EE, Lyall AE, Pasternak O, Kubicki M, ... ... Holt DJ, et al. Cell type-specific manifestations of cortical thickness heterogeneity in schizophrenia. Molecular Psychiatry. PMID 35145230 DOI: 10.1038/s41380-022-01460-7  0.311
2021 Tuominen L, Romaniuk L, Milad MR, Goff DC, Hall J, Holt DJ. Impairment in acquisition of conditioned fear in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34588608 DOI: 10.1038/s41386-021-01193-1  0.366
2021 Wang J, Hart KL, Qi W, Ardekani BA, Li C, Marx J, Freudenreich O, Cather C, Holt D, Bello I, Diminich ED, Tang Y, Worthington M, Zeng B, Wu R, et al. Association of Aripiprazole With Reduced Hippocampal Atrophy During Maintenance Treatment of First-Episode Schizophrenia. Journal of Clinical Psychopharmacology. PMID 33814546 DOI: 10.1097/JCP.0000000000001391  0.353
2021 Tuominen L, DeCross SN, Boeke E, Cassidy CM, Freudenreich O, Shinn AK, Tootell RBH, Holt DJ. Neural abnormalities in fear generalization in schizophrenia and associations with negative symptoms. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 33524600 DOI: 10.1016/j.bpsc.2021.01.006  0.786
2020 Worthington MA, Petkova E, Freudenreich O, Cather C, Holt D, Bello I, Diminich E, Tang Y, Ardekani BA, Zeng B, Wu R, Fan X, Zhao J, Wang J, Goff DC. Air pollution and hippocampal atrophy in first episode schizophrenia. Schizophrenia Research. PMID 32169403 DOI: 10.1016/J.Schres.2020.03.001  0.34
2020 Zhang R, Yang Z, Huang J, Wang Y, Zhou H, Wang Y, Lui SSY, Cheung E, Ongur D, Holt D, Chan R. M141. INDIVIDUALS WITH SCHIZOTYPAL TRAITS SHOW A UNIQUE PATTERN OF CAUDATE ACTIVATION IN PROSPECTION OF POSITIVE EMOTION COMPARED TO HEALTHY CONTROLS Schizophrenia Bulletin. 46: S189-S189. DOI: 10.1093/Schbul/Sbaa030.453  0.399
2019 Barbour T, Holmes AJ, Farabaugh AH, DeCross SN, Coombs G, Boeke EA, Wolthusen RPF, Nyer M, Pedrelli P, Fava M, Holt DJ. Elevated Amygdala Activity in Young Adults With Familial Risk for Depression: A Potential Marker of Low Resilience. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 31948836 DOI: 10.1016/J.Bpsc.2019.10.010  0.733
2019 Pelletier-Baldelli A, Holt DJ. At Issue: Are Negative Symptoms Merely the "Real World" Consequences of Deficits in Social Cognition? Schizophrenia Bulletin. PMID 31598707 DOI: 10.1093/schbul/sbz095  0.306
2019 DeCross SN, Farabaugh AH, Holmes AJ, Ward M, Boeke EA, Wolthusen RPF, Coombs G, Nyer M, Fava M, Buckner RL, Holt DJ. Increased amygdala-visual cortex connectivity in youth with persecutory ideation. Psychological Medicine. 1-11. PMID 30744715 DOI: 10.1017/S0033291718004221  0.77
2019 Goff DC, Freudenreich O, Cather C, Holt D, Bello I, Diminich E, Tang Y, Ardekani BA, Worthington M, Zeng B, Wu R, Fan X, Li C, Troxel A, Wang J, et al. Citalopram in first episode schizophrenia: The DECIFER trial. Schizophrenia Research. PMID 30709746 DOI: 10.1016/J.Schres.2019.01.028  0.41
2019 Holt D, DeCross S, Coman D, Shapero B, Holmes A, Buckner R, Fava M, Farabaugh A. 3.4 CHANGES IN AMYGDALA AND HIPPOCAMPAL FUNCTIONAL CONNECTIVITY IN SUBCLINICAL PSYCHOSIS: RELATIONSHIP TO SYMPTOM PERSISTENCE, PARANOIA AND ABERRANT SALIENCE Schizophrenia Bulletin. 45: S90-S91. DOI: 10.1093/Schbul/Sbz022.006  0.382
2019 Tuominen L, Deng W, Leathem L, Mow J, Barbour T, Holt D. S77. ANHEDONIA IN NON-PSYCHOTIC INDIVIDUALS IS ASSOCIATED WITH DIMINISHED FEAR GENERALIZATION Schizophrenia Bulletin. 45: S336-S337. DOI: 10.1093/SCHBUL/SBZ020.622  0.318
2019 Deng Y, Tuominen L, Leathem L, Mow J, Barbour T, Holt D. T187. Persecutory Beliefs are Associated With Abnormal Medial Temporal Lobe Responses During Fear Learning Biological Psychiatry. 85: S202. DOI: 10.1016/j.biopsych.2019.03.510  0.311
2018 Tuominen L, Boeke E, DeCross S, Wolthusen RP, Nasr S, Milad M, Vangel M, Tootell R, Holt D. The relationship of perceptual discrimination to neural mechanisms of fear generalization. Neuroimage. 188: 445-455. PMID 30572112 DOI: 10.1016/j.neuroimage.2018.12.034  0.754
2018 Shapero BG, Farabaugh A, Terechina O, DeCross S, Cheung JC, Fava M, Holt DJ. Understanding the effects of emotional reactivity on depression and suicidal thoughts and behaviors: Moderating effects of childhood adversity and resilience. Journal of Affective Disorders. 245: 419-427. PMID 30423470 DOI: 10.1016/j.jad.2018.11.033  0.741
2018 Wolthusen RPF, Coombs G, Boeke EA, Ehrlich S, DeCross SN, Nasr S, Holt DJ. Correlation Between Levels of Delusional Beliefs and Perfusion of the Hippocampus and an Associated Network in a Non-Help-Seeking Population. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 3: 178-186. PMID 29529413 DOI: 10.1016/J.Bpsc.2017.06.007  0.779
2018 Tuominen L, Vettermann R, Ge T, Ho N, Holmes A, Sabuncu M, Smoller J, Lee P, Buckner R, Roffman J, Holt D. T242. Genetic Risk Loading for Schizophrenia, Bipolar Disorder, and Major Depression and Hippocampal Subregion Volumes Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.579  0.397
2017 Blokland GAM, Del Re EC, Mesholam-Gately RI, Jovicich J, Trampush JW, Keshavan MS, DeLisi LE, Walters JTR, Turner JA, Malhotra AK, Lencz T, Shenton ME, Voineskos AN, Rujescu D, Giegling I, ... ... Holt DJ, et al. The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) consortium: A collaborative cognitive and neuroimaging genetics project. Schizophrenia Research. PMID 28982554 DOI: 10.1016/J.Schres.2017.09.024  0.587
2017 Tuominen L, DeCross S, Nasr S, Boeke E, Wolthusen R, Tootell R, Freudenreich O, Shinn A, Holt D. 52. Abnormal Anterior Insula Activity During Fear Generalization in Schizophrenia Schizophrenia Bulletin. 43: S27-S27. DOI: 10.1093/schbul/sbx021.071  0.485
2016 Holt DJ. A Pathway to Understanding Emotional Dysfunction in Schizophrenia. Jama Psychiatry. PMID 27145062 DOI: 10.1001/jamapsychiatry.2016.0172  0.316
2016 Holt DJ, Boeke EA, Coombs G, DeCross SN, Cassidy BS, Stufflebeam S, Rauch SL, Tootell RB. Corrigendum to abnormalities in personal space and parietal-frontal function in schizophrenia. Neuroimage. Clinical. 11: 538. PMID 27144121 DOI: 10.1016/J.Nicl.2016.03.018  0.754
2016 Ho NF, Iglesias JE, Sum MY, Kuswanto CN, Sitoh YY, De Souza J, Hong Z, Fischl B, Roffman JL, Zhou J, Sim K, Holt DJ. Progression from selective to general involvement of hippocampal subfields in schizophrenia. Molecular Psychiatry. PMID 26903271 DOI: 10.1038/Mp.2016.4  0.354
2015 Brent BK, Rosso IM, Thermenos HW, Holt DJ, Faraone SV, Makris N, Tsuang MT, Seidman LJ. Alterations of lateral temporal cortical gray matter and facial memory as vulnerability indicators for schizophrenia: An MRI study in youth at familial high-risk for schizophrenia. Schizophrenia Research. PMID 26621001 DOI: 10.1016/J.Schres.2015.11.013  0.373
2015 Holt DJ, Boeke EA, Coombs G, DeCross SN, Cassidy BS, Stufflebeam S, Rauch SL, Tootell RB. Abnormalities in personal space and parietal-frontal function in schizophrenia. Neuroimage. Clinical. 9: 233-43. PMID 26484048 DOI: 10.1016/J.Nicl.2015.07.008  0.773
2015 Maher S, Ekstrom T, Holt D, Ongur D, Chen Y. The Core Brain Region for Face Processing in Schizophrenia Lacks Face Selectivity. Schizophrenia Bulletin. PMID 26453911 DOI: 10.1093/schbul/sbv140  0.416
2015 Wolthusen RP, Hass J, Walton E, Turner JA, Rössner V, Sponheim SR, Ho BC, Holt DJ, Gollub RL, Calhoun V, Ehrlich S. Genetic underpinnings of left superior temporal gyrus thickness in patients with schizophrenia. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-11. PMID 26305511 DOI: 10.3109/15622975.2015.1062915  0.608
2015 Wolthusen RP, Hass J, Walton E, Turner JA, Rössner V, Sponheim SR, Ho BC, Holt DJ, Gollub RL, Calhoun V, Ehrlich S. Genetic underpinnings of left superior temporal gyrus thickness in patients with schizophrenia. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-11. PMID 26249676 DOI: 10.3109/15622975.2015.1062915  0.614
2015 Mueller S, Wang D, Pan R, Holt DJ, Liu H. Abnormalities in hemispheric specialization of caudate nucleus connectivity in schizophrenia. Jama Psychiatry. 72: 552-60. PMID 25830688 DOI: 10.1001/jamapsychiatry.2014.3176  0.324
2015 Hass J, Walton E, Kirsten H, Turner J, Wolthusen R, Roessner V, Sponheim SR, Holt D, Gollub R, Calhoun VD, Ehrlich S. Complexin2 modulates working memory-related neural activity in patients with schizophrenia. European Archives of Psychiatry and Clinical Neuroscience. 265: 137-45. PMID 25297695 DOI: 10.1007/S00406-014-0550-4  0.677
2014 Brent BK, Seidman LJ, Coombs G, Keshavan MS, Moran JM, Holt DJ. Neural responses during social reflection in relatives of schizophrenia patients: relationship to subclinical delusions. Schizophrenia Research. 157: 292-8. PMID 24951401 DOI: 10.1016/J.Schres.2014.05.033  0.576
2014 Coombs G, Loggia ML, Greve DN, Holt DJ. Amygdala perfusion is predicted by its functional connectivity with the ventromedial prefrontal cortex and negative affect. Plos One. 9: e97466. PMID 24816735 DOI: 10.1371/Journal.Pone.0097466  0.497
2014 Holt DJ, Cassidy BS, Yue X, Rauch SL, Boeke EA, Nasr S, Tootell RB, Coombs G. Neural correlates of personal space intrusion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4123-34. PMID 24647934 DOI: 10.1523/Jneurosci.0686-13.2014  0.7
2014 Schneider CE, White T, Hass J, Geisler D, Wallace SR, Roessner V, Holt DJ, Calhoun VD, Gollub RL, Ehrlich S. Smoking status as a potential confounder in the study of brain structure in schizophrenia. Journal of Psychiatric Research. 50: 84-91. PMID 24373929 DOI: 10.1016/J.Jpsychires.2013.12.004  0.457
2014 Brent BK, Seidman LJ, Thermenos HW, Holt DJ, Keshavan MS. Self-disturbances as a possible premorbid indicator of schizophrenia risk: a neurodevelopmental perspective. Schizophrenia Research. 152: 73-80. PMID 23932148 DOI: 10.1016/J.Schres.2013.07.038  0.34
2014 Brent BK, Coombs G, Keshavan MS, Seidman LJ, Moran JM, Holt DJ. Subclinical delusional thinking predicts lateral temporal cortex responses during social reflection. Social Cognitive and Affective Neuroscience. 9: 273-82. PMID 23160817 DOI: 10.7490/F1000Research.1090655.1  0.571
2013 Pedrelli P, Nyer M, Holt D, Bakow BR, Fava M, Baer L, Cassiello C, Mulligan M, Cusin C, Farabaugh A. Correlates of irritability in college students with depressive symptoms. The Journal of Nervous and Mental Disease. 201: 953-8. PMID 24177482 DOI: 10.1097/Nmd.0000000000000038  0.328
2013 Linnman C, Coombs G, Goff DC, Holt DJ. Lack of insula reactivity to aversive stimuli in schizophrenia. Schizophrenia Research. 143: 150-7. PMID 23201307 DOI: 10.1016/J.Schres.2012.10.038  0.593
2012 Holt DJ, Coombs G, Zeidan MA, Goff DC, Milad MR. Failure of neural responses to safety cues in schizophrenia. Archives of General Psychiatry. 69: 893-903. PMID 22945619 DOI: 10.1001/Archgenpsychiatry.2011.2310  0.577
2012 Ehrlich S, Yendiki A, Greve DN, Manoach DS, Ho BC, White T, Schulz SC, Goff DC, Gollub RL, Holt DJ. Striatal function in relation to negative symptoms in schizophrenia. Psychological Medicine. 42: 267-82. PMID 21733291 DOI: 10.1017/S003329171100119X  0.376
2011 Michael AM, King MD, Ehrlich S, Pearlson G, White T, Holt DJ, Andreasen NC, Sakoglu U, Ho BC, Schulz SC, Calhoun VD. A Data-Driven Investigation of Gray Matter-Function Correlations in Schizophrenia during a Working Memory Task. Frontiers in Human Neuroscience. 5: 71. PMID 21886614 DOI: 10.3389/Fnhum.2011.00071  0.685
2011 Holt DJ, Cassidy BS, Andrews-Hanna JR, Lee SM, Coombs G, Goff DC, Gabrieli JD, Moran JM. An anterior-to-posterior shift in midline cortical activity in schizophrenia during self-reflection. Biological Psychiatry. 69: 415-23. PMID 21144498 DOI: 10.1016/J.Biopsych.2010.10.003  0.729
2011 Yue X, Cassidy BS, Devaney KJ, Holt DJ, Tootell RB. Lower-level stimulus features strongly influence responses in the fusiform face area. Cerebral Cortex (New York, N.Y. : 1991). 21: 35-47. PMID 20375074 DOI: 10.1093/Cercor/Bhq050  0.607
2011 Holt DJ, Lakshmanan B, Freudenreich O, Goff DC, Rauch SL, Kuperberg GR. Dysfunction of a cortical midline network during emotional appraisals in schizophrenia. Schizophrenia Bulletin. 37: 164-76. PMID 19605517 DOI: 10.1093/Schbul/Sbp067  0.365
2011 Kuperberg GR, Kreher DA, Swain A, Goff DC, Holt DJ. Selective emotional processing deficits to social vignettes in schizophrenia: an ERP study. Schizophrenia Bulletin. 37: 148-63. PMID 19564165 DOI: 10.1093/Schbul/Sbp018  0.311
2010 Tong SY, Lilliebridge RA, Holt DC, Coombs GW, Currie BJ, Giffard PM. Rapid detection of H and R Panton-Valentine leukocidin isoforms in Staphylococcus aureus by high-resolution melting analysis. Diagnostic Microbiology and Infectious Disease. 67: 399-401. PMID 20638613 DOI: 10.1016/j.diagmicrobio.2010.03.015  0.358
2010 Ehrlich S, Morrow EM, Roffman JL, Wallace SR, Naylor M, Bockholt HJ, Lundquist A, Yendiki A, Ho BC, White T, Manoach DS, Clark VP, Calhoun VD, Gollub RL, Holt DJ. The COMT Val108/158Met polymorphism and medial temporal lobe volumetry in patients with schizophrenia and healthy adults. Neuroimage. 53: 992-1000. PMID 20026221 DOI: 10.1016/J.Neuroimage.2009.12.046  0.474
2010 Holt DJ, Lebron-Milad K, Milad MR, Rauch SL, Pitman RK, Orr SP, Cassidy BS, Walsh JP, Goff DC. Extinction memory is impaired in schizophrenia | La memoria de extinción está deteriorada en la esquizofrenia Psiquiatria Biologica. 17: 22-31. DOI: 10.1016/J.Psiq.2010.01.005  0.567
2009 Holt DJ, Lebron-Milad K, Milad MR, Rauch SL, Pitman RK, Orr SP, Cassidy BS, Walsh JP, Goff DC. Extinction memory is impaired in schizophrenia. Biological Psychiatry. 65: 455-63. PMID 18986648 DOI: 10.1016/J.Biopsych.2008.09.017  0.694
2008 Kuperberg G, Kreher D, Goff D, Swain A, Holt D. SELECTIVE NEURAL DEFICITS IN COMPREHENDING EMOTIONAL INFORMATION WITHIN SOCIAL VIGNETTES IN SCHIZOPHRENIA Schizophrenia Research. 102: 21-22. DOI: 10.1016/S0920-9964(08)70069-0  0.421
2007 Kuperberg GR, Deckersbach T, Holt DJ, Goff D, West WC. Increased temporal and prefrontal activity in response to semantic associations in schizophrenia. Archives of General Psychiatry. 64: 138-51. PMID 17283282 DOI: 10.1001/Archpsyc.64.2.138  0.34
2006 Freudenreich O, Cather C, Holt D. Stimulant misuse in college for "pseudo-attention deficit disorder" during schizophrenia prodrome. The American Journal of Psychiatry. 163: 2019. PMID 17074965 DOI: 10.1176/Ajp.2006.163.11.2019  0.395
2006 Holt DJ, Kunkel L, Weiss AP, Goff DC, Wright CI, Shin LM, Rauch SL, Hootnick J, Heckers S. Increased medial temporal lobe activation during the passive viewing of emotional and neutral facial expressions in schizophrenia. Schizophrenia Research. 82: 153-62. PMID 16377154 DOI: 10.1016/J.Schres.2005.09.021  0.387
2005 Holt DJ, Weiss AP, Rauch SL, Wright CI, Zalesak M, Goff DC, Ditman T, Welsh RC, Heckers S. Sustained activation of the hippocampus in response to fearful faces in schizophrenia. Biological Psychiatry. 57: 1011-9. PMID 15860342 DOI: 10.1016/J.Biopsych.2005.01.033  0.395
2000 Bachus S, Holt D, Agrawal Y, Hyde T, Herman M, Saper C, Kleinman J. 505. Striatal preprosomatostatin mRNA in schizophrenia Biological Psychiatry. 47: S153. DOI: 10.1016/S0006-3223(00)00775-7  0.303
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