Shane Antony Liddelow - Publications

Affiliations: 
2018- New York University School of Medicine, New York, NY, United States 
Area:
glia, astrocytes, reactive astrocytes, blood-brain barrier, development
Website:
https://med.nyu.edu/faculty/shane-a-liddelow

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Saunders NR, Dziegielewska KM, Fame RM, Lehtinen MK, Liddelow SA. The choroid plexus: a missing link in our understanding of brain development and function. Physiological Reviews. PMID 36173801 DOI: 10.1152/physrev.00060.2021  0.342
2022 Labib D, Wang Z, Prakash P, Zimmer M, Smith MD, Frazel PW, Barbar L, Sapar ML, Calabresi PA, Peng J, Liddelow SA, Fossati V. Proteomic Alterations and Novel Markers of Neurotoxic Reactive Astrocytes in Human Induced Pluripotent Stem Cell Models. Frontiers in Molecular Neuroscience. 15: 870085. PMID 35592112 DOI: 10.3389/fnmol.2022.870085  0.784
2022 Sadick JS, O'Dea MR, Hasel P, Dykstra T, Faustin A, Liddelow SA. Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer's disease. Neuron. PMID 35381189 DOI: 10.1016/j.neuron.2022.03.008  0.798
2022 Wareham LK, Liddelow SA, Temple S, Benowitz LI, Di Polo A, Wellington C, Goldberg JL, He Z, Duan X, Bu G, Davis AA, Shekhar K, Torre A, Chan DC, Canto-Soler MV, et al. Solving neurodegeneration: common mechanisms and strategies for new treatments. Molecular Neurodegeneration. 17: 23. PMID 35313950 DOI: 10.1186/s13024-022-00524-0  0.511
2022 Kleffman K, Levinson G, Rose IVL, Blumenberg LM, Shadaloey SAA, Dhabaria A, Wong E, Galan-Echevarria F, Karz A, Argibay D, Von Itter R, Floristan A, Baptiste G, Eskow NM, Tranos JA, ... ... Liddelow SA, et al. Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis. Cancer Discovery. PMID 35262173 DOI: 10.1158/2159-8290.CD-21-1006  0.303
2021 Bandler RC, Vitali I, Delgado RN, Ho MC, Dvoretskova E, Ibarra Molinas JS, Frazel PW, Mohammadkhani M, Machold R, Maedler S, Liddelow SA, Nowakowski TJ, Fishell G, Mayer C. Single-cell delineation of lineage and genetic identity in the mouse brain. Nature. PMID 34912118 DOI: 10.1038/s41586-021-04237-0  0.793
2021 Guttenplan KA, Weigel MK, Prakash P, Wijewardhane PR, Hasel P, Rufen-Blanchette U, Münch AE, Blum JA, Fine J, Neal MC, Bruce KD, Gitler AD, Chopra G, Liddelow SA, Barres BA. Neurotoxic reactive astrocytes induce cell death via saturated lipids. Nature. PMID 34616039 DOI: 10.1038/s41586-021-03960-y  0.761
2021 Prakash P, Jethava KP, Korte N, Izquierdo P, Favuzzi E, Rose IVL, Guttenplan KA, Manchanda P, Dutta S, Rochet JC, Fishell G, Liddelow SA, Attwell D, Chopra G. Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time. Chemical Science. 12: 10901-10918. PMID 34476070 DOI: 10.1039/d1sc03486c  0.694
2021 Hasel P, Rose IVL, Sadick JS, Kim RD, Liddelow SA. Neuroinflammatory astrocyte subtypes in the mouse brain. Nature Neuroscience. PMID 34413515 DOI: 10.1038/s41593-021-00905-6  0.799
2021 Kwon AHK, Liddelow SA. Astrocytes have a license to kill inflammatory T cells. Immunity. 54: 614-616. PMID 33852828 DOI: 10.1016/j.immuni.2021.03.015  0.789
2021 Escartin C, Galea E, Lakatos A, O'Callaghan JP, Petzold GC, Serrano-Pozo A, Steinhäuser C, Volterra A, Carmignoto G, Agarwal A, Allen NJ, Araque A, Barbeito L, Barzilai A, Bergles DE, ... ... Liddelow SA, et al. Reactive astrocyte nomenclature, definitions, and future directions. Nature Neuroscience. PMID 33589835 DOI: 10.1038/s41593-020-00783-4  0.502
2021 Han RT, Kim RD, Molofsky AV, Liddelow SA. Astrocyte-immune cell interactions in physiology and pathology. Immunity. 54: 211-224. PMID 33567261 DOI: 10.1016/j.immuni.2021.01.013  0.602
2020 Joshi AU, Minhas PS, Liddelow SA, Haileselassie B, Andreasson KI, Dorn GW, Mochly-Rosen D. Author Correction: Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration. Nature Neuroscience. PMID 33324000 DOI: 10.1038/s41593-020-00774-5  0.423
2020 Ineichen BV, Di Palma S, Laczko E, Liddelow SA, Neumann S, Schwab ME, Mosberger AC. Regional Differences in Penetration of the Protein Stabilizer Trimethoprim (TMP) in the Rat Central Nervous System. Frontiers in Molecular Neuroscience. 13: 167. PMID 33013318 DOI: 10.3389/Fnmol.2020.00167  0.413
2020 Zhang J, Velmeshev D, Hashimoto K, Huang YH, Hofmann JW, Shi X, Chen J, Leidal AM, Dishart JG, Cahill MK, Kelley KW, Liddelow SA, Seeley WW, Miller BL, Walther TC, et al. Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. Nature. PMID 32866962 DOI: 10.1038/S41586-020-2709-7  0.679
2020 Liddelow SA, Marsh SE, Stevens B. Microglia and Astrocytes in Disease: Dynamic Duo or Partners in Crime? Trends in Immunology. PMID 32819809 DOI: 10.1016/J.It.2020.07.006  0.59
2020 Guttenplan KA, Weigel MK, Adler DI, Couthouis J, Liddelow SA, Gitler AD, Barres BA. Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model. Nature Communications. 11: 3753. PMID 32719333 DOI: 10.1038/S41467-020-17514-9  0.556
2020 Guttenplan KA, Stafford BK, El-Danaf RN, Adler DI, Münch AE, Weigel MK, Huberman AD, Liddelow SA. Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury. Cell Reports. 31: 107776. PMID 32579912 DOI: 10.1016/J.Celrep.2020.107776  0.652
2020 Gibson EM, Bennett FC, Gillespie SM, Güler AD, Gutmann DH, Halpern CH, Kucenas SC, Kushida CA, Lemieux M, Liddelow S, Macauley SL, Li Q, Quinn MA, Roberts LW, Saligrama N, et al. How Support of Early Career Researchers Can Reset Science in the Post-COVID19 World. Cell. PMID 32533917 DOI: 10.1016/J.Cell.2020.05.045  0.696
2020 Barbar L, Jain T, Zimmer M, Kruglikov I, Sadick JS, Wang M, Kalpana K, Rose IVL, Burstein SR, Rusielewicz T, Nijsure M, Guttenplan KA, di Domenico A, Croft G, Zhang B, ... ... Liddelow SA, et al. CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes. Neuron. PMID 32485136 DOI: 10.1016/J.Neuron.2020.05.014  0.802
2020 Sadick JS, Crawford LA, Cramer HC, Franck C, Liddelow SA, Darling EM. Generating Cell Type-Specific Protein Signatures from Non-symptomatic and Diseased Tissues. Annals of Biomedical Engineering. PMID 32303872 DOI: 10.1007/S10439-020-02507-Y  0.789
2019 Joshi AU, Minhas PS, Liddelow SA, Haileselassie B, Andreasson KI, Dorn GW, Mochly-Rosen D. Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration. Nature Neuroscience. 22: 1635-1648. PMID 31551592 DOI: 10.1038/S41593-019-0486-0  0.54
2019 Bennett FC, Liddelow SA. Microglia Metabolic Breakdown Drives Alzheimer's Pathology. Cell Metabolism. 30: 405-406. PMID 31484050 DOI: 10.1016/J.Cmet.2019.08.017  0.322
2019 Hartmann K, Sepulveda-Falla D, Rose IVL, Madore C, Muth C, Matschke J, Butovsky O, Liddelow S, Glatzel M, Krasemann S. Complement 3-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia. Acta Neuropathologica Communications. 7: 83. PMID 31118110 DOI: 10.1186/S40478-019-0735-1  0.37
2019 Liddelow SA, Sofroniew MV. Astrocytes usurp neurons as a disease focus. Nature Neuroscience. PMID 30858602 DOI: 10.1038/S41593-019-0367-6  0.333
2019 Liddelow SA. Modern approaches to investigating non-neuronal aspects of Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 33: 1528-1535. PMID 30703873 DOI: 10.1096/Fj.201802592  0.324
2019 Sadick JS, Liddelow SA. DonꞋt forget astrocytes when targeting AlzheimerꞋs disease. British Journal of Pharmacology. PMID 30636042 DOI: 10.1111/Bph.14568  0.787
2019 Guttenplan KA, Liddelow SA. Astrocytes and microglia: Models and tools. The Journal of Experimental Medicine. 216: 71-83. PMID 30541903 DOI: 10.1084/Jem.20180200  0.363
2019 Liddelow SA. PL-03-01: INGE GRUNDKE-IQBAL AWARD FOR ALZHEIMER'S RESEARCH: NEUROTOXIC REACTIVE ASTROCYTES ARE INDUCED BY ACTIVATED MICROGLIA Alzheimer's & Dementia. 15: P872-P872. DOI: 10.1016/J.Jalz.2019.06.4616  0.301
2018 Liddelow SA, Eroglu C, Clandinin TR. Ben Barres (1954-2017). Neuron. 97: 1211-1213. PMID 33245869 DOI: 10.1016/j.neuron.2018.03.005  0.448
2018 Gibson EM, Nagaraja S, Ocampo A, Tam LT, Wood LS, Pallegar PN, Greene JJ, Geraghty AC, Goldstein AK, Ni L, Woo PJ, Barres BA, Liddelow S, Vogel H, Monje M. Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment. Cell. PMID 30528430 DOI: 10.1016/J.Cell.2018.10.049  0.561
2018 Lananna BV, Nadarajah CJ, Izumo M, Cedeño MR, Xiong DD, Dimitry J, Tso CF, McKee CA, Griffin P, Sheehan PW, Haspel JA, Barres BA, Liddelow SA, Takahashi JS, Karatsoreos IN, et al. Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1. Cell Reports. 25: 1-9.e5. PMID 30282019 DOI: 10.1016/J.Celrep.2018.09.015  0.64
2018 Yun SP, Kam TI, Panicker N, Kim S, Oh Y, Park JS, Kwon SH, Park YJ, Karuppagounder SS, Park H, Kim S, Oh N, Kim NA, Lee S, Brahmachari S, ... ... Liddelow SA, et al. Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease. Nature Medicine. PMID 29892066 DOI: 10.1038/S41591-018-0051-5  0.561
2018 Clarke LE, Liddelow SA, Chakraborty C, Münch AE, Heiman M, Barres BA. Normal aging induces A1-like astrocyte reactivity. Proceedings of the National Academy of Sciences of the United States of America. PMID 29437957 DOI: 10.1073/Pnas.1800165115  0.601
2018 Vainchtein ID, Chin G, Cho FS, Kelley KW, Miller JG, Chien EC, Liddelow SA, Nguyen PT, Nakao-Inoue H, Dorman LC, Akil O, Joshita S, Barres BA, Paz JT, Molofsky AB, et al. Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development. Science (New York, N.Y.). PMID 29420261 DOI: 10.1126/Science.Aal3589  0.552
2018 Liddelow SA, Eroglu C, Clandinin TR. Ben Barres (1954–2017) Neuron. 97: 1211-1213. DOI: 10.1016/J.Neuron.2018.03.005  0.499
2017 Liddelow S. Bypassing the barrier: new routes for delivery of macromolecules to the central nervous system. The Journal of Physiology. 596: 361-362. PMID 29171665 DOI: 10.1113/Jp275499  0.303
2017 Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, et al. ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy. Nature. 549: 523-527. PMID 28959956 DOI: 10.1038/Nature24016  0.563
2017 Clarke LE, Liddelow SA. Neurobiology: Diversity reaches the stars. Nature. 548: 396-397. PMID 28836597 DOI: 10.1038/548396A  0.385
2017 Liddelow SA, Barres BA. Reactive Astrocytes: Production, Function, and Therapeutic Potential. Immunity. 46: 957-967. PMID 28636962 DOI: 10.1016/J.Immuni.2017.06.006  0.629
2017 Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Münch AE, Chung WS, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature. PMID 28099414 DOI: 10.1038/Nature21029  0.667
2016 Liddelow SA, Barres BA. Regeneration: Not everything is scary about a glial scar. Nature. PMID 27027287 DOI: 10.1038/Nature17318  0.533
2016 Stolp HB, Liddelow SA, Saunders NR. Editorial: Ontogeny and Phylogeny of Brain Barrier Mechanisms. Frontiers in Neuroscience. 10: 41. PMID 26909020 DOI: 10.3389/Fnins.2016.00041  0.793
2016 Bennett ML, Bennett FC, Liddelow SA, Ajami B, Zamanian JL, Fernhoff NB, Mulinyawe SB, Bohlen CJ, Adil A, Tucker A, Weissman IL, Chang EF, Li G, Grant GA, Hayden Gephart MG, et al. New tools for studying microglia in the mouse and human CNS. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884166 DOI: 10.1073/Pnas.1525528113  0.655
2016 Liddelow SA, Dziegielewska KM, Ek CJ, Habgood MD, Bauer H, Bauer HC, Lindsay H, Wakefield MJ, Strazielle N, Kratzer I, Møllgård K, Ghersi-Egea JF, Saunders NR. Correction: Mechanisms That Determine the Internal Environment of the Developing Brain: A Transcriptomic, Functional and Ultrastructural Approach. Plos One. 11: e0147680. PMID 26783757 DOI: 10.1371/journal.pone.0147680  0.779
2016 Liddelow S, Hoyer D. Astrocytes: adhesion molecules and immunomodulation. Current Drug Targets. PMID 26721411 DOI: 10.2174/1389450117666160101120703  0.432
2015 Liddelow S, Barres B. SnapShot: Astrocytes in Health and Disease Cell. 162: 1170-1170.e1. PMID 26317476 DOI: 10.1016/J.Cell.2015.08.029  0.63
2015 Saunders NR, Dziegielewska KM, Møllgård K, Habgood MD, Wakefield MJ, Lindsay H, Stratzielle N, Ghersi-Egea JF, Liddelow SA. Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study. Frontiers in Neuroscience. 9: 123. PMID 25972776 DOI: 10.3389/Fnins.2015.00123  0.787
2015 Liddelow SA. Development of the choroid plexus and blood-CSF barrier. Frontiers in Neuroscience. 9: 32. PMID 25784848 DOI: 10.3389/Fnins.2015.00032  0.506
2015 Whish S, Dziegielewska KM, Møllgård K, Noor NM, Liddelow SA, Habgood MD, Richardson SJ, Saunders NR. The inner CSF-brain barrier: developmentally controlled access to the brain via intercellular junctions. Frontiers in Neuroscience. 9: 16. PMID 25729345 DOI: 10.3389/Fnins.2015.00016  0.828
2014 Liddelow SA, Dzi?gielewska KM, Møllgård K, Whish SC, Noor NM, Wheaton BJ, Gehwolf R, Wagner A, Traweger A, Bauer H, Bauer HC, Saunders NR. Cellular specificity of the blood-CSF barrier for albumin transfer across the choroid plexus epithelium. Plos One. 9: e106592. PMID 25211495 DOI: 10.1371/Journal.Pone.0106592  0.708
2014 Zhang Y, Chen K, Sloan SA, Bennett ML, Scholze AR, O'Keeffe S, Phatnani HP, Guarnieri P, Caneda C, Ruderisch N, Deng S, Liddelow SA, Zhang C, Daneman R, Maniatis T, et al. An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11929-47. PMID 25186741 DOI: 10.1523/Jneurosci.1860-14.2014  0.772
2014 Saunders NR, Noor NM, Dziegielewska KM, Wheaton BJ, Liddelow SA, Steer DL, Ek CJ, Habgood MD, Wakefield MJ, Lindsay H, Truettner J, Miller RD, Smith AI, Dietrich WD. Age-dependent transcriptome and proteome following transection of neonatal spinal cord of Monodelphis domestica (South American grey short-tailed opossum). Plos One. 9: e99080. PMID 24914927 DOI: 10.1371/Journal.Pone.0099080  0.772
2013 Stolp HB, Liddelow SA, Sá-Pereira I, Dziegielewska KM, Saunders NR. Immune responses at brain barriers and implications for brain development and neurological function in later life. Frontiers in Integrative Neuroscience. 7: 61. PMID 23986663 DOI: 10.3389/Fnint.2013.00061  0.805
2013 Kratzer I, Liddelow SA, Saunders NR, Dziegielewska KM, Strazielle N, Ghersi-Egea JF. Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotection. Fluids and Barriers of the Cns. 10: 25. PMID 23915922 DOI: 10.1186/2045-8118-10-25  0.811
2013 Liddelow SA, Dziegielewska KM, Ek CJ, Habgood MD, Bauer H, Bauer HC, Lindsay H, Wakefield MJ, Strazielle N, Kratzer I, MøllgÃ¥rd K, Ghersi-Egea JF, Saunders NR. Mechanisms that determine the internal environment of the developing brain: a transcriptomic, functional and ultrastructural approach. Plos One. 8: e65629. PMID 23843944 DOI: 10.1371/Journal.Pone.0065629  0.816
2013 Saunders NR, Daneman R, Dziegielewska KM, Liddelow SA. Transporters of the blood-brain and blood-CSF interfaces in development and in the adult. Molecular Aspects of Medicine. 34: 742-52. PMID 23506907 DOI: 10.1016/J.Mam.2012.11.006  0.811
2012 Saunders NR, Liddelow SA, Dziegielewska KM. Barrier mechanisms in the developing brain. Frontiers in Pharmacology. 3: 46. PMID 22479246 DOI: 10.3389/Fphar.2012.00046  0.822
2012 Liddelow SA, Temple S, MøllgÃ¥rd K, Gehwolf R, Wagner A, Bauer H, Bauer HC, Phoenix TN, Dziegielewska KM, Saunders NR. Molecular characterisation of transport mechanisms at the developing mouse blood-CSF interface: a transcriptome approach. Plos One. 7: e33554. PMID 22457777 DOI: 10.1371/Journal.Pone.0033554  0.821
2011 Liddelow SA, Dziegielewska KM, MøllgÃ¥rd K, Phoenix TN, Temple S, Vandeberg JL, Saunders NR. SPARC/osteonectin, an endogenous mechanism for targeting albumin to the blood-cerebrospinal fluid interface during brain development. The European Journal of Neuroscience. 34: 1062-73. PMID 21899600 DOI: 10.1111/J.1460-9568.2011.07821.X  0.818
2011 Liddelow SA. Fluids and barriers of the CNS: a historical viewpoint. Fluids and Barriers of the Cns. 8: 2. PMID 21349150 DOI: 10.1186/2045-8118-8-2  0.358
2011 Liddelow SA, Dziegielewska KM, VandeBerg JL, Noor NM, Potter AM, Saunders NR. Modification of protein transfer across blood/cerebrospinal fluid barrier in response to altered plasma protein composition during development. The European Journal of Neuroscience. 33: 391-400. PMID 21138490 DOI: 10.1111/J.1460-9568.2010.07509.X  0.806
2011 Saunders NR, Ek CJ, Habgood MD, Johansson P, Liddelow S, Dziegielewska KM. Assessing blood-cerebrospinal fluid barrier permeability in the rat embryo. Methods in Molecular Biology (Clifton, N.J.). 686: 247-65. PMID 21082375 DOI: 10.1007/978-1-60761-938-3_11  0.782
2010 Liddelow SA, Dziegielewska KM, Vandeberg JL, Saunders NR. Development of the lateral ventricular choroid plexus in a marsupial, Monodelphis domestica. Cerebrospinal Fluid Research. 7: 16. PMID 20920364 DOI: 10.1186/1743-8454-7-16  0.789
2010 Ek CJ, Wong A, Liddelow SA, Johansson PA, Dziegielewska KM, Saunders NR. Efflux mechanisms at the developing brain barriers: ABC-transporters in the fetal and postnatal rat. Toxicology Letters. 197: 51-9. PMID 20466047 DOI: 10.1016/J.Toxlet.2010.04.025  0.818
2009 Liddelow SA, Dziegielewska KM, Ek CJ, Johansson PA, Potter AM, Saunders NR. Cellular transfer of macromolecules across the developing choroid plexus of Monodelphis domestica. The European Journal of Neuroscience. 29: 253-66. PMID 19200232 DOI: 10.1111/J.1460-9568.2008.06571.X  0.813
2008 Johansson PA, Dziegielewska KM, Liddelow SA, Saunders NR. The blood-CSF barrier explained: when development is not immaturity. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 30: 237-48. PMID 18293362 DOI: 10.1002/Bies.20718  0.816
2006 Johansson PA, Dziegielewska KM, Ek CJ, Habgood MD, Liddelow SA, Potter AM, Stolp HB, Saunders NR. Blood-CSF barrier function in the rat embryo. The European Journal of Neuroscience. 24: 65-76. PMID 16800861 DOI: 10.1111/J.1460-9568.2006.04904.X  0.791
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