Year |
Citation |
Score |
2023 |
Zhu N, LeDuc CA, Fennoy I, Laferrère B, Doege CA, Shen Y, Chung WK, Leibel RL. Rare predicted loss of function alleles in Bassoon (BSN) are associated with obesity. Npj Genomic Medicine. 8: 33. PMID 37865656 DOI: 10.1038/s41525-023-00376-7 |
0.508 |
|
2023 |
Zhu N, LeDuc CA, Fennoy I, Laferr Re B, Doege CA, Shen Y, Chung WK, Leibel RL. Predicted loss of function alleles in Bassoon (BSN) are associated with obesity. Medrxiv : the Preprint Server For Health Sciences. PMID 36865254 DOI: 10.1101/2023.02.19.23285978 |
0.5 |
|
2022 |
González BJ, Zhao H, Niu J, Williams DJ, Lee J, Goulbourne CN, Xing Y, Wang Y, Oberholzer J, Blumenkrantz MH, Chen X, LeDuc CA, Chung WK, Colecraft HM, Gromada J, ... ... Leibel RL, et al. Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency. Communications Biology. 5: 779. PMID 35918471 DOI: 10.1038/s42003-022-03696-z |
0.402 |
|
2021 |
De Rosa MC, Glover HJ, Stratigopoulos G, LeDuc CA, Su Q, Shen Y, Sleeman MW, Chung WK, Leibel RL, Altarejos JY, Doege CA. Gene expression atlas of energy balance brain regions. Jci Insight. PMID 34283813 DOI: 10.1172/jci.insight.149137 |
0.49 |
|
2021 |
Breidbart E, Deng L, Lanzano P, Fan X, Guo J, Leibel RL, LeDuc CA, Chung WK. Frequency and characterization of mutations in genes in a large cohort of patients referred to MODY registry. Journal of Pediatric Endocrinology & Metabolism : Jpem. 34: 633-638. PMID 33852230 DOI: 10.1515/jpem-2020-0501 |
0.374 |
|
2020 |
Yaghootkar H, Zhang Y, Spracklen CN, Karaderi T, Huang LO, Bradfield J, Schurmann C, Fine RS, Preuss MH, Kutalik Z, Wittemans LB, Lu Y, Metz S, Willems SM, Li-Gao R, ... ... Leibel RL, et al. Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. Diabetes. PMID 32917775 DOI: 10.2337/Db20-0070 |
0.382 |
|
2020 |
Lugo-Candelas C, Pang Y, Lee S, Cha J, Hong S, Ranzenhofer L, Korn R, Davis H, McInerny H, Schebendach J, Chung WK, Leibel RL, Walsh BT, Posner J, Rosenbaum M, et al. Differences in brain structure and function in children with the obesity-risk allele. Obesity Science & Practice. 6: 409-424. PMID 32874676 DOI: 10.1002/Osp4.417 |
0.486 |
|
2020 |
Skowronski AA, LeDuc CA, Foo KS, Goffer Y, Burnett LC, Egli D, Leibel RL. Physiological consequences of transient hyperleptinemia during discrete developmental periods on body weight in mice. Science Translational Medicine. 12. PMID 31894105 DOI: 10.1126/Scitranslmed.Aax6629 |
0.321 |
|
2020 |
LeDuc CA, Leibel RL. Auto-Regulation of Leptin Neurobiology. Cell Metabolism. 30: 614-616. PMID 31577926 DOI: 10.1016/j.cmet.2019.09.006 |
0.336 |
|
2019 |
Ranzenhofer LM, Mayer LES, Davis HA, Mielke-Maday HK, McInerney H, Korn R, Gupta N, Brown AJ, Schebendach J, Tanofsky-Kraff M, Thaker V, Chung WK, Leibel RL, Walsh BT, Rosenbaum M. The FTO Gene and Measured Food Intake in 5- to 10-Year-Old Children Without Obesity. Obesity (Silver Spring, Md.). 27: 1023-1029. PMID 31119882 DOI: 10.1002/Oby.22464 |
0.499 |
|
2018 |
Melhorn SJ, Askren MK, Chung WK, Kratz M, Bosch TA, Tyagi V, Webb MF, De Leon MRB, Grabowski TJ, Leibel RL, Schur EA. FTO genotype impacts food intake and corticolimbic activation. The American Journal of Clinical Nutrition. 107: 145-154. PMID 29529147 DOI: 10.1093/Ajcn/Nqx029 |
0.426 |
|
2018 |
Carli JFM, LeDuc CA, Zhang Y, Stratigopoulos G, Leibel RL. The role of Rpgrip1l, a component of the primary cilium, in adipocyte development and function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701216R. PMID 29466054 DOI: 10.1096/fj.201701216R |
0.324 |
|
2017 |
Schwartz MW, Seeley RJ, Zeltser LM, Drewnowski A, Ravussin E, Redman LM, Leibel RL. Obesity Pathogenesis: An Endocrine Society Scientific Statement. Endocrine Reviews. 38: 267-296. PMID 28898979 DOI: 10.1210/Er.2017-00111 |
0.335 |
|
2017 |
Mosialou I, Shikhel S, Liu JM, Maurizi A, Luo N, He Z, Huang Y, Zong H, Friedman RA, Barasch J, Lanzano P, Deng L, Leibel RL, Rubin M, Nicholas T, et al. MC4R-dependent suppression of appetite by bone-derived lipocalin 2. Nature. PMID 28273060 DOI: 10.1038/Nature21697 |
0.392 |
|
2017 |
Hua H, Shang L, Martinez H, Freeby M, Gallagher MP, Ludwig T, Deng L, Greenberg E, LeDuc C, Chung WK, Goland R, Leibel RL, Egli D. iPSC-derived β cells model diabetes due to glucokinase deficiency. The Journal of Clinical Investigation. PMID 28094769 DOI: 10.1172/JCI92775 |
0.334 |
|
2016 |
Burnett LC, LeDuc CA, Sulsona CR, Paull D, Rausch R, Eddiry S, Carli JF, Morabito MV, Skowronski AA, Hubner G, Zimmer M, Wang L, Day R, Levy B, Fennoy I, ... ... Leibel RL, et al. Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome. The Journal of Clinical Investigation. PMID 27941249 DOI: 10.1172/Jci88648 |
0.319 |
|
2016 |
Stratigopoulos G, Burnett LC, Rausch R, Gill R, Penn DB, Skowronski AA, LeDuc CA, Lanzano AJ, Zhang P, Storm DR, Egli D, Leibel RL. Hypomorphism of Fto and Rpgrip1l causes obesity in mice. The Journal of Clinical Investigation. PMID 27064284 DOI: 10.1172/Jci85526 |
0.392 |
|
2016 |
Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, ... ... Leibel RL, et al. Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nature Communications. 7: 10494. PMID 26833098 DOI: 10.1038/Ncomms10494 |
0.352 |
|
2014 |
Stratigopoulos G, Martin Carli JF, O'Day DR, Wang L, Leduc CA, Lanzano P, Chung WK, Rosenbaum M, Egli D, Doherty DA, Leibel RL. Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice. Cell Metabolism. 19: 767-79. PMID 24807221 DOI: 10.1016/J.Cmet.2014.04.009 |
0.51 |
|
2014 |
Shang L, Hua H, Foo K, Martinez H, Watanabe K, Zimmer M, Kahler DJ, Freeby M, Chung W, LeDuc C, Goland R, Leibel RL, Egli D. β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome. Diabetes. 63: 923-33. PMID 24227685 DOI: 10.2337/Db13-0717 |
0.39 |
|
2014 |
Gill R, Cheung YH, Shen Y, Lanzano P, Mirza NM, Ten S, MacLaren NK, Motaghedi R, Han JC, Yanovski JA, Leibel RL, Chung WK. Whole-Exome sequencing identifies novel LEPR mutations in individuals with severe early onset obesity Obesity. 22: 576-584. PMID 23616257 DOI: 10.1002/Oby.20492 |
0.488 |
|
2013 |
Hua H, Shang L, Martinez H, Freeby M, Gallagher MP, Ludwig T, Deng L, Greenberg E, Leduc C, Chung WK, Goland R, Leibel RL, Egli D. iPSC-derived β cells model diabetes due to glucokinase deficiency. The Journal of Clinical Investigation. 123: 3146-53. PMID 23778137 DOI: 10.1172/Jci67638 |
0.395 |
|
2011 |
Tiwari HK, Patki A, Lieberman J, Stroup TS, Allison DB, Leibel RL, Chung WK. Association of Allelic Variation in Genes Mediating Aspects of Energy Homeostasis with Weight Gain during Administration of Antipsychotic Drugs (CATIE Study). Frontiers in Genetics. 2: 56. PMID 22039372 DOI: 10.3389/Fgene.2011.00056 |
0.418 |
|
2011 |
Stratigopoulos G, LeDuc CA, Cremona ML, Chung WK, Leibel RL. Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling. The Journal of Biological Chemistry. 286: 2155-70. PMID 21037323 DOI: 10.1074/jbc.M110.188482 |
0.454 |
|
2011 |
Carmody JS, Wan P, Accili D, Zeltser LM, Leibel RL. Respective contributions of maternal insulin resistance and diet to metabolic and hypothalamic phenotypes of progeny. Obesity (Silver Spring, Md.). 19: 492-9. PMID 20948526 DOI: 10.1038/Oby.2010.245 |
0.354 |
|
2010 |
Myers MG, Leibel RL, Seeley RJ, Schwartz MW. Obesity and leptin resistance: distinguishing cause from effect. Trends in Endocrinology and Metabolism: Tem. 21: 643-51. PMID 20846876 DOI: 10.1016/J.Tem.2010.08.002 |
0.331 |
|
2009 |
Chung WK, Shin M, Jaramillo TC, Leibel RL, LeDuc CA, Fischer SG, Tzilianos E, Gheith AA, Lewis AS, Chetkovich DM. Absence epilepsy in apathetic, a spontaneous mutant mouse lacking the h channel subunit, HCN2. Neurobiology of Disease. 33: 499-508. PMID 19150498 DOI: 10.1016/j.nbd.2008.12.004 |
0.324 |
|
2009 |
Chung WK, Patki A, Matsuoka N, Boyer BB, Liu N, Musani SK, Goropashnaya AV, Tan PL, Katsanis N, Johnson SB, Gregersen PK, Allison DB, Leibel RL, Tiwari HK. Analysis of 30 genes (355 SNPS) related to energy homeostasis for association with adiposity in European-American and Yup'ik Eskimo populations. Human Heredity. 67: 193-205. PMID 19077438 DOI: 10.1159/000181158 |
0.476 |
|
2009 |
Stratigopoulos G, LeDuc CA, Matsuoka N, Gutman R, Rausch R, Robertson SA, Myers MG, Chung WK, Chua SC, Leibel RL. Functional consequences of the human leptin receptor (LEPR) Q223R transversion. Obesity (Silver Spring, Md.). 17: 126-35. PMID 18997673 DOI: 10.1038/oby.2008.489 |
0.462 |
|
2008 |
Chung WK, Leibel RL. Considerations regarding the genetics of obesity Obesity. 16. PMID 19037210 DOI: 10.1038/oby.2008.514 |
0.508 |
|
2008 |
Dokmanovic-Chouinard M, Chung WK, Chevre JC, Watson E, Yonan J, Wiegand B, Bromberg Y, Wakae N, Wright CV, Overton J, Ghosh S, Sathe GM, Ammala CE, Brown KK, Ito R, ... ... Leibel RL, et al. Positional cloning of "Lisch-Like", a candidate modifier of susceptibility to type 2 diabetes in mice. Plos Genetics. 4: e1000137. PMID 18654634 DOI: 10.1371/Journal.Pgen.1000137 |
0.422 |
|
2008 |
Weisberg SP, Leibel R, Tortoriello DV. Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity. Endocrinology. 149: 3549-58. PMID 18403477 DOI: 10.1210/en.2008-0262 |
0.324 |
|
2008 |
Stratigopoulos G, Padilla SL, LeDuc CA, Watson E, Hattersley AT, McCarthy MI, Zeltser LM, Chung WK, Leibel RL. Regulation of Fto/Ftm gene expression in mice and humans. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 294: R1185-96. PMID 18256137 DOI: 10.1152/Ajpregu.00839.2007 |
0.521 |
|
2007 |
Klein S, Allison DB, Heymsfield SB, Kelley DE, Leibel RL, Nonas C, Kahn R. Waist circumference and cardiometabolic risk: a consensus statement from Shaping America's Health: Association for Weight Management and Obesity Prevention; NAASO, The Obesity Society; the American Society for Nutrition; and the American Diabetes Association. The American Journal of Clinical Nutrition. 85: 1197-202. PMID 17490953 DOI: 10.1093/Ajcn/85.5.1197 |
0.323 |
|
2006 |
Chung WK, Leibel RL. The links between obesity, leptin, and prostate cancer Cancer Journal. 12: 178-181. PMID 16803674 DOI: 10.1097/00130404-200605000-00004 |
0.402 |
|
2006 |
Phan LK, Chung WK, Leibel RL. The mahoganoid mutation (Mgrn1md) improves insulin sensitivity in mice with mutations in the melanocortin signaling pathway independently of effects on adiposity. American Journal of Physiology. Endocrinology and Metabolism. 291: E611-20. PMID 16638826 DOI: 10.1152/ajpendo.00034.2006 |
0.504 |
|
2005 |
Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, Charo I, Leibel RL, Ferrante AW. CCR2 modulates inflammatory and metabolic effects of high-fat feeding. The Journal of Clinical Investigation. 116: 115-24. PMID 16341265 DOI: 10.1172/JCI24335 |
0.35 |
|
2005 |
Chung WK, Leibel RL. Molecular physiology of syndromic obesities in humans Trends in Endocrinology and Metabolism. 16: 267-272. PMID 16005242 DOI: 10.1016/j.tem.2005.06.009 |
0.472 |
|
2004 |
Guo KY, Halo P, Leibel RL, Zhang Y. Effects of obesity on the relationship of leptin mRNA expression and adipocyte size in anatomically distinct fat depots in mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 287: R112-9. PMID 15001430 DOI: 10.1152/ajpregu.00028.2004 |
0.338 |
|
2003 |
Phan LK, Lin F, LeDuc CA, Chung WK, Leibel RL. The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein. The Journal of Clinical Investigation. 110: 1449-59. PMID 12438443 DOI: 10.1172/JCI16131 |
0.459 |
|
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