| Year |
Citation |
Score |
| 2024 |
Mulas C, Stammers M, Salomaa SI, Heinzen C, Suter DM, Smith A, Chalut KJ. ERK signalling eliminates Nanog and maintains Oct4 to drive the formative pluripotency transition. Development (Cambridge, England). 151. PMID 39069943 DOI: 10.1242/dev.203106 |
0.366 |
|
| 2024 |
Radley A, Boeing S, Smith A. Branching topology of the human embryo transcriptome revealed by entropy sort feature weighting. Development (Cambridge, England). PMID 38691188 DOI: 10.1242/dev.202832 |
0.466 |
|
| 2023 |
Agostinho de Sousa J, Wong CW, Dunkel I, Owens T, Voigt P, Hodgson A, Baker D, Schulz EG, Reik W, Smith A, Rostovskaya M, von Meyenn F. Epigenetic dynamics during capacitation of naïve human pluripotent stem cells. Science Advances. 9: eadg1936. PMID 37774033 DOI: 10.1126/sciadv.adg1936 |
0.407 |
|
| 2023 |
Ludwig TE, Andrews PW, Barbaric I, Benvenisty N, Bhattacharyya A, Crook JM, Daheron LM, Draper JS, Healy LE, Huch M, Inamdar MS, Jensen KB, Kurtz A, Lancaster MA, Liberali P, ... ... Smith AG, et al. ISSCR standards for the use of human stem cells in basic research. Stem Cell Reports. 18: 1744-1752. PMID 37703820 DOI: 10.1016/j.stemcr.2023.08.003 |
0.447 |
|
| 2023 |
Miroshnikova YA, Shahbazi MN, Negrete J, Chalut KJ, Smith A. Cell state transitions: catch them if you can. Development (Cambridge, England). 150. PMID 36930528 DOI: 10.1242/dev.201139 |
0.407 |
|
| 2022 |
Dattani A, Huang T, Liddle C, Smith A, Guo G. Suppression of YAP safeguards human naïve pluripotency. Development (Cambridge, England). PMID 36398796 DOI: 10.1242/dev.200988 |
0.329 |
|
| 2022 |
Radley A, Corujo-Simon E, Nichols J, Smith A, Dunn SJ. Entropy sorting of single-cell RNA sequencing data reveals the inner cell mass in the human pre-implantation embryo. Stem Cell Reports. PMID 36240776 DOI: 10.1016/j.stemcr.2022.09.007 |
0.369 |
|
| 2022 |
Huth M, Santini L, Galimberti E, Ramesmayer J, Titz-Teixeira F, Sehlke R, Oberhuemer M, Stummer S, Herzog V, Garmhausen M, Romeike M, Chugunova A, Leesch F, Holcik L, Weipoltshammer K, ... ... Smith A, et al. NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation. Genes & Development. 36: 348-367. PMID 35241478 DOI: 10.1101/gad.347690.120 |
0.349 |
|
| 2021 |
Mulas C, Chaigne A, Smith A, Chalut KJ. Cell state transitions: definitions and challenges. Development (Cambridge, England). 148. PMID 34932803 DOI: 10.1242/dev.199950 |
0.302 |
|
| 2021 |
Kinoshita M, Kobayashi T, Planells B, Klisch D, Spindlow D, Masaki H, Bornelöv S, Stirparo GG, Matsunari H, Uchikura A, Lamas-Toranzo I, Nichols J, Nakauchi H, Nagashima H, Alberio R, ... Smith A, et al. Pluripotent stem cells related to embryonic disc exhibit common self-renewal requirements in diverse livestock species. Development (Cambridge, England). 148. PMID 34874452 DOI: 10.1242/dev.199901 |
0.594 |
|
| 2021 |
Kinoshita M, Barber M, Mansfield W, Cui Y, Spindlow D, Stirparo GG, Dietmann S, Nichols J, Smith A. Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency. Cell Stem Cell. 28: 2180. PMID 34861148 DOI: 10.1016/j.stem.2021.11.002 |
0.506 |
|
| 2021 |
Kinoshita M, Li MA, Barber M, Mansfield W, Dietmann S, Smith A. Disabling de novo DNA methylation in embryonic stem cells allows an illegitimate fate trajectory. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34518230 DOI: 10.1073/pnas.2109475118 |
0.427 |
|
| 2021 |
Yanagida A, Spindlow D, Nichols J, Dattani A, Smith A, Guo G. Naive stem cell blastocyst model captures human embryo lineage segregation. Cell Stem Cell. 28: 1016-1022.e4. PMID 33957081 DOI: 10.1016/j.stem.2021.04.031 |
0.459 |
|
| 2021 |
Guo G, Stirparo GG, Strawbridge SE, Spindlow D, Yang J, Clarke J, Dattani A, Yanagida A, Li MA, Myers S, Özel BN, Nichols J, Smith A. Human naive epiblast cells possess unrestricted lineage potential. Cell Stem Cell. PMID 33831366 DOI: 10.1016/j.stem.2021.02.025 |
0.577 |
|
| 2021 |
Lackner A, Sehlke R, Garmhausen M, Giuseppe Stirparo G, Huth M, Titz-Teixeira F, van der Lelij P, Ramesmayer J, Thomas HF, Ralser M, Santini L, Galimberti E, Sarov M, Stewart AF, Smith A, et al. Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency. The Embo Journal. e105776. PMID 33687089 DOI: 10.15252/embj.2020105776 |
0.401 |
|
| 2020 |
Stirparo GG, Smith A, Guo G. Cancer-Related Mutations Are Not Enriched in Naive Human Pluripotent Stem Cells. Cell Stem Cell. PMID 33321074 DOI: 10.1016/j.stem.2020.11.014 |
0.422 |
|
| 2020 |
Kinoshita M, Barber M, Mansfield W, Cui Y, Spindlow D, Stirparo GG, Dietmann S, Nichols J, Smith A. Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency. Cell Stem Cell. PMID 33271069 DOI: 10.1016/j.stem.2020.11.005 |
0.597 |
|
| 2020 |
Vitillo L, Durance C, Hewitt Z, Moore H, Smith A, Vallier L. GMP-grade neural progenitor derivation and differentiation from clinical-grade human embryonic stem cells. Stem Cell Research & Therapy. 11: 406. PMID 32948237 DOI: 10.1186/s13287-020-01915-0 |
0.414 |
|
| 2020 |
Mulas C, Hodgson AC, Kohler TN, Agley CC, Humphreys P, Kleine-Brüggeney H, Hollfelder F, Smith A, Chalut KJ. Microfluidic platform for 3D cell culture with live imaging and clone retrieval. Lab On a Chip. PMID 32573646 DOI: 10.1039/D0Lc00165A |
0.418 |
|
| 2019 |
Mayer D, Stadler MB, Rittirsch M, Hess D, Lukonin I, Winzi M, Smith A, Buchholz F, Betschinger J. Zfp281 orchestrates interconversion of pluripotent states by engaging Ehmt1 and Zic2. The Embo Journal. e102591. PMID 31782544 DOI: 10.15252/embj.2019102591 |
0.461 |
|
| 2019 |
Bredenkamp N, Yang J, Clarke J, Stirparo GG, von Meyenn F, Dietmann S, Baker D, Drummond R, Ren Y, Li D, Wu C, Rostovskaya M, Eminli-Meissner S, Smith A, Guo G. Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency. Stem Cell Reports. PMID 31708477 DOI: 10.1016/j.stemcr.2019.10.009 |
0.506 |
|
| 2019 |
Ostermann L, Ladewig J, Müller FJ, Kesevan J, Tailor J, Smith A, Brüstle O, Koch P. In vitro recapitulation of developmental transitions in human neural stem cells. Stem Cells (Dayton, Ohio). PMID 31339593 DOI: 10.1002/stem.3065 |
0.595 |
|
| 2019 |
Huang M, Tailor J, Zhen Q, Gillmor AH, Miller ML, Weishaupt H, Chen J, Zheng T, Nash EK, McHenry LK, An Z, Ye F, Takashima Y, Clarke J, Ayetey H, ... ... Smith A, et al. Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis. Cell Stem Cell. PMID 31204176 DOI: 10.1016/J.Stem.2019.05.013 |
0.533 |
|
| 2019 |
Bredenkamp N, Stirparo GG, Nichols J, Smith A, Guo G. The Cell-Surface Marker Sushi Containing Domain 2 Facilitates Establishment of Human Naive Pluripotent Stem Cells. Stem Cell Reports. PMID 31031191 DOI: 10.1016/j.stemcr.2019.03.014 |
0.54 |
|
| 2019 |
Kalkan T, Bornelöv S, Mulas C, Diamanti E, Lohoff T, Ralser M, Middelkamp S, Lombard P, Nichols J, Smith A. Complementary Activity of ETV5, RBPJ, and TCF3 Drives Formative Transition from Naive Pluripotency. Cell Stem Cell. 24: 785-801.e7. PMID 31031137 DOI: 10.1016/j.stem.2019.03.017 |
0.344 |
|
| 2019 |
Mulas C, Kalkan T, von Meyenn F, Leitch HG, Nichols J, Smith A. Correction: Defined conditions for propagation and manipulation of mouse embryonic stem cells (doi:10.1242/dev.173146). Development (Cambridge, England). 146. PMID 30975648 DOI: 10.1242/dev.178970 |
0.509 |
|
| 2019 |
Rostovskaya M, Stirparo GG, Smith A. Capacitation of human naïve pluripotent stem cells for multi-lineage differentiation. Development (Cambridge, England). 146. PMID 30944104 DOI: 10.1242/dev.172916 |
0.484 |
|
| 2019 |
Mulas C, Kalkan T, von Meyenn F, Leitch HG, Nichols J, Smith A. Defined conditions for propagation and manipulation of mouse embryonic stem cells. Development (Cambridge, England). 146. PMID 30914406 DOI: 10.1242/dev.173146 |
0.523 |
|
| 2018 |
Kleine-Brüggeney H, van Vliet LD, Mulas C, Gielen F, Agley CC, Silva JCR, Smith A, Chalut K, Hollfelder F. Long-Term Perfusion Culture of Monoclonal Embryonic Stem Cells in 3D Hydrogel Beads for Continuous Optical Analysis of Differentiation. Small (Weinheim An Der Bergstrasse, Germany). e1804576. PMID 30570812 DOI: 10.1002/Smll.201804576 |
0.481 |
|
| 2018 |
Dunn SJ, Li MA, Carbognin E, Smith A, Martello G. A common molecular logic determines embryonic stem cell self-renewal and reprogramming. The Embo Journal. PMID 30482756 DOI: 10.15252/embj.2018100003 |
0.395 |
|
| 2018 |
Boroviak T, Stirparo GG, Dietmann S, Hernando-Herraez I, Mohammed H, Reik W, Smith A, Sasaki E, Nichols J, Bertone P. Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development. Development (Cambridge, England). 145. PMID 30413530 DOI: 10.1242/Dev.167833 |
0.329 |
|
| 2018 |
Sutherland L, Ruhe M, Gattegno-Ho D, Mann K, Greaves J, Koscielniak M, Meek S, Lu Z, Waterfall M, Taylor R, Tsakiridis A, Brown H, Maciver SK, Joshi A, Clinton M, ... ... Smith A, et al. LIF-dependent survival of embryonic stem cells is regulated by a novel palmitoylated Gab1 signalling protein. Journal of Cell Science. PMID 30154213 DOI: 10.1242/jcs.222257 |
0.327 |
|
| 2018 |
Nett IR, Mulas C, Gatto L, Lilley KS, Smith A. Negative feedback via RSK modulates Erk-dependent progression from naïve pluripotency. Embo Reports. PMID 29895711 DOI: 10.15252/embr.201745642 |
0.365 |
|
| 2018 |
Dorn T, Kornherr J, Parrotta EI, Zawada D, Ayetey H, Santamaria G, Iop L, Mastantuono E, Sinnecker D, Goedel A, Dirschinger RJ, My I, Laue S, Bozoglu T, Baarlink C, ... ... Smith AG, et al. Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity. The Embo Journal. PMID 29764980 DOI: 10.15252/Embj.201798133 |
0.384 |
|
| 2018 |
Stirparo GG, Boroviak T, Guo G, Nichols J, Smith A, Bertone P. Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human preimplantation epiblast. Development (Cambridge, England). PMID 29361568 DOI: 10.1242/Dev.158501 |
0.521 |
|
| 2018 |
Kinoshita M, Smith A. Pluripotency Deconstructed. Development, Growth & Differentiation. PMID 29359419 DOI: 10.1111/dgd.12419 |
0.429 |
|
| 2018 |
Zhang M, Leitch HG, Tang WWC, Festuccia N, Hall-Ponsele E, Nichols J, Surani MA, Smith A, Chambers I. Esrrb Complementation Rescues Development of Nanog-Null Germ Cells. Cell Reports. 22: 332-339. PMID 29320730 DOI: 10.1016/j.celrep.2017.12.060 |
0.454 |
|
| 2017 |
Chen Y, Spitzer S, Agathou S, Karadottir RT, Smith A. Gene Editing in Rat Embryonic Stem Cells to Produce In Vitro Models and In Vivo Reporters. Stem Cell Reports. 9: 1262-1274. PMID 29020614 DOI: 10.1016/j.stemcr.2017.09.005 |
0.528 |
|
| 2017 |
Greaves RB, Dietmann S, Smith A, Stepney S, Halley JD. A conceptual and computational framework for modelling and understanding the non-equilibrium gene regulatory networks of mouse embryonic stem cells. Plos Computational Biology. 13: e1005713. PMID 28863148 DOI: 10.1371/journal.pcbi.1005713 |
0.417 |
|
| 2017 |
Guo G, von Meyenn F, Rostovskaya M, Clarke J, Dietmann S, Baker D, Sahakyan A, Myers S, Bertone P, Reik W, Plath K, Smith A. Epigenetic resetting of human pluripotency. Development (Cambridge, England). 144: 2748-2763. PMID 28765214 DOI: 10.1242/Dev.146811 |
0.468 |
|
| 2017 |
Mulas C, Kalkan T, Smith A. NODAL Secures Pluripotency upon Embryonic Stem Cell Progression from the Ground State. Stem Cell Reports. PMID 28669603 DOI: 10.1016/j.stemcr.2017.05.033 |
0.54 |
|
| 2017 |
Ying QL, Smith A. The Art of Capturing Pluripotency: Creating the Right Culture. Stem Cell Reports. 8: 1457-1464. PMID 28591647 DOI: 10.1016/J.Stemcr.2017.05.020 |
0.587 |
|
| 2017 |
Kalkan T, Olova N, Roode M, Mulas C, Lee HJ, Nett I, Marks H, Walker R, Stunnenberg HG, Lilley KS, Nichols J, Reik W, Bertone P, Smith A. Tracking the embryonic stem cell transition from ground state pluripotency. Development (Cambridge, England). PMID 28174249 DOI: 10.1242/Dev.142711 |
0.516 |
|
| 2017 |
Smith A. Formative pluripotency: the executive phase in a developmental continuum. Development (Cambridge, England). 144: 365-373. PMID 28143843 DOI: 10.1242/dev.142679 |
0.33 |
|
| 2016 |
Guo G, von Meyenn F, Santos F, Chen Y, Reik W, Bertone P, Smith A, Nichols J. Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass. Stem Cell Reports. PMID 26947977 DOI: 10.1016/J.Stemcr.2016.02.005 |
0.609 |
|
| 2016 |
Scognamiglio R, Cabezas-Wallscheid N, Thier MC, Altamura S, Reyes A, Prendergast ÁM, Baumgärtner D, Carnevalli LS, Atzberger A, Haas S, von Paleske L, Boroviak T, Wörsdörfer P, Essers MA, Kloz U, ... ... Smith A, et al. Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause. Cell. 164: 668-80. PMID 26871632 DOI: 10.1016/J.Cell.2015.12.033 |
0.418 |
|
| 2016 |
Rostovskaya M, Bredenkamp N, Smith A. Towards consistent generation of pancreatic lineage progenitors from human pluripotent stem cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370: 20140365. PMID 26416676 DOI: 10.1098/rstb.2014.0365 |
0.563 |
|
| 2015 |
Boroviak T, Loos R, Lombard P, Okahara J, Behr R, Sasaki E, Nichols J, Smith A, Bertone P. Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis. Developmental Cell. 35: 366-82. PMID 26555056 DOI: 10.1016/J.Devcel.2015.10.011 |
0.426 |
|
| 2015 |
Kalkan T, Smith A. Mapping the route from naive pluripotency to lineage specification. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369. PMID 25349449 DOI: 10.1098/rstb.2013.0540 |
0.397 |
|
| 2015 |
Martello G, Smith A. The nature of embryonic stem cells. Annual Review of Cell and Developmental Biology. 30: 647-75. PMID 25288119 DOI: 10.1146/annurev-cellbio-100913-013116 |
0.569 |
|
| 2014 |
Takashima Y, Guo G, Loos R, Nichols J, Ficz G, Krueger F, Oxley D, Santos F, Clarke J, Mansfield W, Reik W, Bertone P, Smith A. Resetting transcription factor control circuitry toward ground-state pluripotency in human. Cell. 158: 1254-69. PMID 25215486 DOI: 10.1016/J.Cell.2014.08.029 |
0.452 |
|
| 2014 |
Yang SH, Kalkan T, Morissroe C, Marks H, Stunnenberg H, Smith A, Sharrocks AD. Otx2 and Oct4 drive early enhancer activation during embryonic stem cell transition from naive pluripotency. Cell Reports. 7: 1968-81. PMID 24931607 DOI: 10.1016/J.Celrep.2014.05.037 |
0.472 |
|
| 2014 |
Boroviak T, Loos R, Bertone P, Smith A, Nichols J. The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. Nature Cell Biology. 16: 516-28. PMID 24859004 DOI: 10.1038/Ncb2965 |
0.544 |
|
| 2014 |
Herberg M, Kalkan T, Glauche I, Smith A, Roeder I. A model-based analysis of culture-dependent phenotypes of mESCs. Plos One. 9: e92496. PMID 24643025 DOI: 10.1371/journal.pone.0092496 |
0.404 |
|
| 2014 |
Smith A. Cell biology: Potency unchained. Nature. 505: 622-3. PMID 24476883 DOI: 10.1038/505622a |
0.424 |
|
| 2014 |
Leeb M, Dietmann S, Paramor M, Niwa H, Smith A. Genetic exploration of the exit from self-renewal using haploid embryonic stem cells. Cell Stem Cell. 14: 385-93. PMID 24412312 DOI: 10.1016/j.stem.2013.12.008 |
0.452 |
|
| 2014 |
Mohsen-Kanson T, Hafner AL, Wdziekonski B, Takashima Y, Villageois P, Carrière A, Svensson M, Bagnis C, Chignon-Sicard B, Svensson PA, Casteilla L, Smith A, Dani C. Differentiation of human induced pluripotent stem cells into brown and white adipocytes: role of Pax3. Stem Cells (Dayton, Ohio). 32: 1459-67. PMID 24302443 DOI: 10.1002/stem.1607 |
0.388 |
|
| 2014 |
Smith A. Nanog heterogeneity: tilting at windmills? Cell Stem Cell. 13: 6-7. PMID 23827703 DOI: 10.1016/j.stem.2013.06.016 |
0.427 |
|
| 2013 |
Chen Y, Blair K, Smith A. Robust self-renewal of rat embryonic stem cells requires fine-tuning of glycogen synthase kinase-3 inhibition. Stem Cell Reports. 1: 209-17. PMID 24319657 DOI: 10.1016/j.stemcr.2013.07.003 |
0.444 |
|
| 2013 |
Danovi D, Folarin A, Gogolok S, Ender C, Elbatsh AM, Engström PG, Stricker SH, Gagrica S, Georgian A, Yu D, U KP, Harvey KJ, Ferretti P, Paddison PJ, Preston JE, ... ... Smith A, et al. A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1. Plos One. 8: e77053. PMID 24204733 DOI: 10.1371/Journal.Pone.0077053 |
0.496 |
|
| 2013 |
Leitch HG, Nichols J, Humphreys P, Mulas C, Martello G, Lee C, Jones K, Surani MA, Smith A. Rebuilding pluripotency from primordial germ cells. Stem Cell Reports. 1: 66-78. PMID 24052943 DOI: 10.1016/j.stemcr.2013.03.004 |
0.522 |
|
| 2013 |
Martello G, Bertone P, Smith A. Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor. The Embo Journal. 32: 2561-74. PMID 23942233 DOI: 10.1038/Emboj.2013.177 |
0.398 |
|
| 2013 |
Tailor J, Kittappa R, Leto K, Gates M, Borel M, Paulsen O, Spitzer S, Karadottir RT, Rossi F, Falk A, Smith A. Stem cells expanded from the human embryonic hindbrain stably retain regional specification and high neurogenic potency. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12407-22. PMID 23884946 DOI: 10.1523/JNEUROSCI.0130-13.2013 |
0.555 |
|
| 2013 |
Leitch HG, Smith A. The mammalian germline as a pluripotency cycle. Development (Cambridge, England). 140: 2495-501. PMID 23715543 DOI: 10.1242/dev.091603 |
0.52 |
|
| 2013 |
Pourquié O, Bruneau B, Götz M, Keller G, Smith A. Stem cells and regeneration: a special issue. Development (Cambridge, England). 140: 2445. PMID 23715535 DOI: 10.1242/Dev.098350 |
0.448 |
|
| 2013 |
Bianco P, Barker R, Brüstle O, Cattaneo E, Clevers H, Daley GQ, De Luca M, Goldstein L, Lindvall O, Mummery C, Robey PG, Sattler de Sousa E Brito C, Smith A. Regulation of stem cell therapies under attack in Europe: for whom the bell tolls. The Embo Journal. 32: 1489-95. PMID 23644381 DOI: 10.1038/Emboj.2013.114 |
0.34 |
|
| 2013 |
Betschinger J, Nichols J, Dietmann S, Corrin PD, Paddison PJ, Smith A. Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3. Cell. 153: 335-47. PMID 23582324 DOI: 10.1016/j.cell.2013.03.012 |
0.415 |
|
| 2013 |
Stricker SH, Feber A, Engström PG, Carén H, Kurian KM, Takashima Y, Watts C, Way M, Dirks P, Bertone P, Smith A, Beck S, Pollard SM. Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner. Genes & Development. 27: 654-69. PMID 23512659 DOI: 10.1101/Gad.212662.112 |
0.394 |
|
| 2013 |
Leitch HG, McEwen KR, Turp A, Encheva V, Carroll T, Grabole N, Mansfield W, Nashun B, Knezovich JG, Smith A, Surani MA, Hajkova P. Naive pluripotency is associated with global DNA hypomethylation. Nature Structural & Molecular Biology. 20: 311-6. PMID 23416945 DOI: 10.1038/nsmb.2510 |
0.374 |
|
| 2013 |
McLaren D, Gorba T, Marguerie de Rotrou A, Pillai G, Chappell C, Stacey A, Lingard S, Falk A, Smith A, Koch P, Brüstle O, Vickers R, Tinsley J, Flanders D, Bello P, et al. Automated large-scale culture and medium-throughput chemical screen for modulators of proliferation and viability of human induced pluripotent stem cell-derived neuroepithelial-like stem cells. Journal of Biomolecular Screening. 18: 258-68. PMID 23042076 DOI: 10.1177/1087057112461446 |
0.506 |
|
| 2013 |
Brilli E, Reitano E, Conti L, Conforti P, Gulino R, Consalez GG, Cesana E, Smith A, Rossi F, Cattaneo E. Neural stem cells engrafted in the adult brain fuse with endogenous neurons. Stem Cells and Development. 22: 538-47. PMID 23009360 DOI: 10.1089/Scd.2012.0530 |
0.41 |
|
| 2012 |
Yang SH, Kalkan T, Morrisroe C, Smith A, Sharrocks AD. A genome-wide RNAi screen reveals MAP kinase phosphatases as key ERK pathway regulators during embryonic stem cell differentiation. Plos Genetics. 8: e1003112. PMID 23271975 DOI: 10.1371/Journal.Pgen.1003112 |
0.472 |
|
| 2012 |
Blair K, Leitch HG, Mansfield W, Dumeau CÉ, Humphreys P, Smith AG. Culture parameters for stable expansion, genetic modification and germline transmission of rat pluripotent stem cells. Biology Open. 1: 58-65. PMID 23213369 DOI: 10.1242/bio.2011029 |
0.517 |
|
| 2012 |
Martello G, Sugimoto T, Diamanti E, Joshi A, Hannah R, Ohtsuka S, Göttgens B, Niwa H, Smith A. Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal. Cell Stem Cell. 11: 491-504. PMID 23040478 DOI: 10.1016/j.stem.2012.06.008 |
0.428 |
|
| 2012 |
Leeb M, Walker R, Mansfield B, Nichols J, Smith A, Wutz A. Germline potential of parthenogenetic haploid mouse embryonic stem cells. Development (Cambridge, England). 139: 3301-5. PMID 22912412 DOI: 10.1242/dev.083675 |
0.55 |
|
| 2012 |
Nichols J, Smith A. Pluripotency in the embryo and in culture. Cold Spring Harbor Perspectives in Biology. 4: a008128. PMID 22855723 DOI: 10.1101/cshperspect.a008128 |
0.581 |
|
| 2012 |
van Oosten AL, Costa Y, Smith A, Silva JC. JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency. Nature Communications. 3: 817. PMID 22569365 DOI: 10.1038/ncomms1822 |
0.479 |
|
| 2012 |
Marks H, Kalkan T, Menafra R, Denissov S, Jones K, Hofemeister H, Nichols J, Kranz A, Stewart AF, Smith A, Stunnenberg HG. The transcriptional and epigenomic foundations of ground state pluripotency. Cell. 149: 590-604. PMID 22541430 DOI: 10.1016/j.cell.2012.03.026 |
0.416 |
|
| 2012 |
Fujimoto Y, Abematsu M, Falk A, Tsujimura K, Sanosaka T, Juliandi B, Semi K, Namihira M, Komiya S, Smith A, Nakashima K. Treatment of a mouse model of spinal cord injury by transplantation of human induced pluripotent stem cell-derived long-term self-renewing neuroepithelial-like stem cells. Stem Cells (Dayton, Ohio). 30: 1163-73. PMID 22419556 DOI: 10.1002/stem.1083 |
0.48 |
|
| 2012 |
Camnasio S, Delli Carri A, Lombardo A, Grad I, Mariotti C, Castucci A, Rozell B, Lo Riso P, Castiglioni V, Zuccato C, Rochon C, Takashima Y, Diaferia G, Biunno I, Gellera C, ... ... Smith A, et al. The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity. Neurobiology of Disease. 46: 41-51. PMID 22405424 DOI: 10.1016/J.Nbd.2011.12.042 |
0.475 |
|
| 2012 |
Falk A, Koch P, Kesavan J, Takashima Y, Ladewig J, Alexander M, Wiskow O, Tailor J, Trotter M, Pollard S, Smith A, Brüstle O. Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons. Plos One. 7: e29597. PMID 22272239 DOI: 10.1371/journal.pone.0029597 |
0.532 |
|
| 2012 |
Roode M, Blair K, Snell P, Elder K, Marchant S, Smith A, Nichols J. Human hypoblast formation is not dependent on FGF signalling. Developmental Biology. 361: 358-63. PMID 22079695 DOI: 10.1016/j.ydbio.2011.10.030 |
0.412 |
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| 2011 |
Gómez-López S, Wiskow O, Favaro R, Nicolis SK, Price DJ, Pollard SM, Smith A. Sox2 and Pax6 maintain the proliferative and developmental potential of gliogenic neural stem cells In vitro. Glia. 59: 1588-99. PMID 21766338 DOI: 10.1002/Glia.21201 |
0.577 |
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| 2011 |
Wray J, Kalkan T, Gomez-Lopez S, Eckardt D, Cook A, Kemler R, Smith A. Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nature Cell Biology. 13: 838-45. PMID 21685889 DOI: 10.1038/ncb2267 |
0.421 |
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| 2011 |
Sun Y, Hu J, Zhou L, Pollard SM, Smith A. Interplay between FGF2 and BMP controls the self-renewal, dormancy and differentiation of rat neural stem cells. Journal of Cell Science. 124: 1867-77. PMID 21558414 DOI: 10.1242/jcs.085506 |
0.581 |
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| 2011 |
Guo G, Huang Y, Humphreys P, Wang X, Smith A. A PiggyBac-based recessive screening method to identify pluripotency regulators. Plos One. 6: e18189. PMID 21533166 DOI: 10.1371/Journal.Pone.0018189 |
0.374 |
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| 2011 |
Smith A. 'No' to ban on stem-cell patents. Nature. 472: 418. PMID 21525916 DOI: 10.1038/472418a |
0.536 |
|
| 2011 |
Blair K, Wray J, Smith A. The liberation of embryonic stem cells. Plos Genetics. 7: e1002019. PMID 21490948 DOI: 10.1371/journal.pgen.1002019 |
0.569 |
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| 2011 |
Theunissen TW, van Oosten AL, Castelo-Branco G, Hall J, Smith A, Silva JC. Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions. Current Biology : Cb. 21: 65-71. PMID 21194951 DOI: 10.1016/J.Cub.2010.11.074 |
0.508 |
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| 2011 |
Nichols J, Smith A. The origin and identity of embryonic stem cells. Development (Cambridge, England). 138: 3-8. PMID 21138972 DOI: 10.1242/dev.050831 |
0.545 |
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| 2011 |
Andrews PW, Moore H, Smith A. Human embryonic stem cells: prospects for human health - a 1-day international symposium held at the University of Sheffield. Journal of Anatomy. 200: 221-3. PMID 17103711 DOI: 10.1046/J.1469-7580.2002.00027.X |
0.399 |
|
| 2010 |
Guo G, Smith A. A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency. Development (Cambridge, England). 137: 3185-92. PMID 20823062 DOI: 10.1242/dev.052753 |
0.441 |
|
| 2010 |
Yang J, van Oosten AL, Theunissen TW, Guo G, Silva JC, Smith A. Stat3 activation is limiting for reprogramming to ground state pluripotency. Cell Stem Cell. 7: 319-28. PMID 20804969 DOI: 10.1016/j.stem.2010.06.022 |
0.409 |
|
| 2010 |
Danovi D, Falk A, Humphreys P, Vickers R, Tinsley J, Smith AG, Pollard SM. Imaging-based chemical screens using normal and glioma-derived neural stem cells. Biochemical Society Transactions. 38: 1067-71. PMID 20659005 DOI: 10.1042/BST0381067 |
0.537 |
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| 2010 |
Leitch HG, Blair K, Mansfield W, Ayetey H, Humphreys P, Nichols J, Surani MA, Smith A. Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state. Development (Cambridge, England). 137: 2279-87. PMID 20519324 DOI: 10.1242/dev.050427 |
0.615 |
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| 2010 |
Smith A. Pluripotent stem cells: private obsession and public expectation. Embo Molecular Medicine. 2: 113-6. PMID 20373283 DOI: 10.1002/emmm.201000065 |
0.479 |
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| 2010 |
Kawaguchi J, Nichols J, Gierl MS, Faial T, Smith A. Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos. Development (Cambridge, England). 137: 693-704. PMID 20147374 DOI: 10.1242/dev.046896 |
0.526 |
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| 2010 |
Moretti A, Bellin M, Jung CB, Thies TM, Takashima Y, Bernshausen A, Schiemann M, Fischer S, Moosmang S, Smith AG, Lam JT, Laugwitz KL. Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 700-11. PMID 19850773 DOI: 10.1096/Fj.09-139477 |
0.555 |
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| 2009 |
Hall J, Guo G, Wray J, Eyres I, Nichols J, Grotewold L, Morfopoulou S, Humphreys P, Mansfield W, Walker R, Tomlinson S, Smith A. Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal. Cell Stem Cell. 5: 597-609. PMID 19951688 DOI: 10.1016/j.stem.2009.11.003 |
0.429 |
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| 2009 |
Nichols J, Silva J, Roode M, Smith A. Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Development (Cambridge, England). 136: 3215-22. PMID 19710168 DOI: 10.1242/dev.038893 |
0.474 |
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| 2009 |
Silva J, Nichols J, Theunissen TW, Guo G, van Oosten AL, Barrandon O, Wray J, Yamanaka S, Chambers I, Smith A. Nanog is the gateway to the pluripotent ground state. Cell. 138: 722-37. PMID 19703398 DOI: 10.1016/j.cell.2009.07.039 |
0.435 |
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| 2009 |
Pollard SM, Yoshikawa K, Clarke ID, Danovi D, Stricker S, Russell R, Bayani J, Head R, Lee M, Bernstein M, Squire JA, Smith A, Dirks P. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Cell Stem Cell. 4: 568-80. PMID 19497285 DOI: 10.1016/J.Stem.2009.03.014 |
0.556 |
|
| 2009 |
Nichols J, Smith A. Naive and primed pluripotent states. Cell Stem Cell. 4: 487-92. PMID 19497275 DOI: 10.1016/j.stem.2009.05.015 |
0.474 |
|
| 2009 |
Nichols J, Jones K, Phillips JM, Newland SA, Roode M, Mansfield W, Smith A, Cooke A. Validated germline-competent embryonic stem cell lines from nonobese diabetic mice. Nature Medicine. 15: 814-8. PMID 19491843 DOI: 10.1038/Nm.1996 |
0.302 |
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| 2009 |
Sun Y, Kong W, Falk A, Hu J, Zhou L, Pollard S, Smith A. CD133 (Prominin) negative human neural stem cells are clonogenic and tripotent. Plos One. 4: e5498. PMID 19430532 DOI: 10.1371/journal.pone.0005498 |
0.307 |
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| 2009 |
Guo G, Yang J, Nichols J, Hall JS, Eyres I, Mansfield W, Smith A. Klf4 reverts developmentally programmed restriction of ground state pluripotency Development. 136: 1063-1069. PMID 19224983 DOI: 10.1242/dev.030957 |
0.548 |
|
| 2009 |
Silva J, Barrandon O, Nichols J, Kawaguchi J, Theunissen TW, Smith A. Promotion of reprogramming to ground state pluripotency by signal inhibition. Plos Biology. 6: e253. PMID 18942890 DOI: 10.1371/journal.pbio.0060253 |
0.58 |
|
| 2009 |
Batlle-Morera L, Smith A, Nichols J. Parameters influencing derivation of embryonic stem cells from murine embryos. Genesis (New York, N.Y. : 2000). 46: 758-67. PMID 18837461 DOI: 10.1002/dvg.20442 |
0.392 |
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| 2008 |
Buehr M, Meek S, Blair K, Yang J, Ure J, Silva J, McLay R, Hall J, Ying QL, Smith A. Capture of authentic embryonic stem cells from rat blastocysts. Cell. 135: 1287-98. PMID 19109897 DOI: 10.1016/j.cell.2008.12.007 |
0.545 |
|
| 2008 |
Pollard SM, Wallbank R, Tomlinson S, Grotewold L, Smith A. Fibroblast growth factor induces a neural stem cell phenotype in foetal forebrain progenitors and during embryonic stem cell differentiation. Molecular and Cellular Neurosciences. 38: 393-403. PMID 18504136 DOI: 10.1016/j.mcn.2008.03.012 |
0.552 |
|
| 2008 |
Ying QL, Wray J, Nichols J, Batlle-Morera L, Doble B, Woodgett J, Cohen P, Smith A. The ground state of embryonic stem cell self-renewal. Nature. 453: 519-23. PMID 18497825 DOI: 10.1038/Nature06968 |
0.483 |
|
| 2008 |
Sun Y, Pollard S, Conti L, Toselli M, Biella G, Parkin G, Willatt L, Falk A, Cattaneo E, Smith A. Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture. Molecular and Cellular Neurosciences. 38: 245-58. PMID 18450476 DOI: 10.1016/J.Mcn.2008.02.014 |
0.538 |
|
| 2008 |
Silva J, Smith A. Capturing pluripotency. Cell. 132: 532-6. PMID 18295569 DOI: 10.1016/j.cell.2008.02.006 |
0.539 |
|
| 2008 |
Chambers I, Silva J, Colby D, Nichols J, Nijmeijer B, Robertson M, Vrana J, Jones K, Grotewold L, Smith A. Nanog safeguards pluripotency and mediates germline development. Nature. 450: 1230-4. PMID 18097409 DOI: 10.1038/nature06403 |
0.604 |
|
| 2007 |
Kunath T, Saba-El-Leil MK, Almousailleakh M, Wray J, Meloche S, Smith A. FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. Development (Cambridge, England). 134: 2895-902. PMID 17660198 DOI: 10.1242/Dev.02880 |
0.464 |
|
| 2007 |
Takashima Y, Era T, Nakao K, Kondo S, Kasuga M, Smith AG, Nishikawa S. Neuroepithelial cells supply an initial transient wave of MSC differentiation. Cell. 129: 1377-88. PMID 17604725 DOI: 10.1016/j.cell.2007.04.028 |
0.305 |
|
| 2007 |
Johnson CE, Crawford BE, Stavridis M, Ten Dam G, Wat AL, Rushton G, Ward CM, Wilson V, van Kuppevelt TH, Esko JD, Smith A, Gallagher JT, Merry CL. Essential alterations of heparan sulfate during the differentiation of embryonic stem cells to Sox1-enhanced green fluorescent protein-expressing neural progenitor cells. Stem Cells (Dayton, Ohio). 25: 1913-23. PMID 17464092 DOI: 10.1634/Stemcells.2006-0445 |
0.463 |
|
| 2007 |
Glaser T, Pollard SM, Smith A, Brüstle O. Tripotential differentiation of adherently expandable neural stem (NS) cells. Plos One. 2: e298. PMID 17356704 DOI: 10.1371/journal.pone.0000298 |
0.497 |
|
| 2006 |
Pollard S, Conti L, Smith A. Exploitation of adherent neural stem cells in basic and applied neurobiology Regenerative Medicine. 1: 111-118. PMID 17465825 DOI: 10.2217/17460751.1.1.111 |
0.543 |
|
| 2006 |
Silva J, Chambers I, Pollard S, Smith A. Nanog promotes transfer of pluripotency after cell fusion. Nature. 441: 997-1001. PMID 16791199 DOI: 10.1038/nature04914 |
0.545 |
|
| 2006 |
Pollard SM, Conti L, Sun Y, Goffredo D, Smith A. Adherent neural stem (NS) cells from fetal and adult forebrain. Cerebral Cortex (New York, N.Y. : 1991). 16: i112-20. PMID 16766697 DOI: 10.1093/cercor/bhj167 |
0.586 |
|
| 2006 |
Blelloch R, Wang Z, Meissner A, Pollard S, Smith A, Jaenisch R. Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus. Stem Cells (Dayton, Ohio). 24: 2007-13. PMID 16709876 DOI: 10.1634/Stemcells.2006-0050 |
0.486 |
|
| 2006 |
Lowell S, Benchoua A, Heavey B, Smith AG. Notch promotes neural lineage entry by pluripotent embryonic stem cells. Plos Biology. 4: e121. PMID 16594731 DOI: 10.1371/journal.pbio.0040121 |
0.52 |
|
| 2006 |
Smith A. The battlefield of pluripotency. Cell. 123: 757-60. PMID 16325569 DOI: 10.1016/j.cell.2005.11.012 |
0.516 |
|
| 2005 |
Wilmut I, West MD, Lanza RP, Gearhart JD, Smith A, Colman A, Trounson AO, Campbell KH. Human embryonic stem cells. Science (New York, N.Y.). 310: 1903. PMID 16352868 DOI: 10.1126/Science.1123832 |
0.318 |
|
| 2005 |
Conti L, Pollard SM, Gorba T, Reitano E, Toselli M, Biella G, Sun Y, Sanzone S, Ying QL, Cattaneo E, Smith A. Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. Plos Biology. 3: e283. PMID 16086633 DOI: 10.1371/Journal.Pbio.0030283 |
0.599 |
|
| 2005 |
Matveeva NM, Pristyazhnyuk IE, Temirova SA, Menzorov AG, Vasilkova A, Shilov AG, Smith A, Serov OL. Unequal segregation of parental chromosomes in embryonic stem cell hybrids. Molecular Reproduction and Development. 71: 305-14. PMID 15806559 DOI: 10.1002/Mrd.20266 |
0.307 |
|
| 2005 |
Kawaguchi J, Mee PJ, Smith AG. Osteogenic and chondrogenic differentiation of embryonic stem cells in response to specific growth factors. Bone. 36: 758-69. PMID 15794925 DOI: 10.1016/j.bone.2004.07.019 |
0.448 |
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| 2004 |
Zhao S, Nichols J, Smith AG, Li M. SoxB transcription factors specify neuroectodermal lineage choice in ES cells. Molecular and Cellular Neurosciences. 27: 332-42. PMID 15519247 DOI: 10.1016/J.Mcn.2004.08.002 |
0.488 |
|
| 2004 |
Chambers I, Smith A. Self-renewal of teratocarcinoma and embryonic stem cells. Oncogene. 23: 7150-60. PMID 15378075 DOI: 10.1038/sj.onc.1207930 |
0.457 |
|
| 2003 |
Ying QL, Smith AG. Defined conditions for neural commitment and differentiation. Methods in Enzymology. 365: 327-41. PMID 14696356 DOI: 10.1016/S0076-6879(03)65023-8 |
0.4 |
|
| 2003 |
Ying QL, Nichols J, Chambers I, Smith A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell. 115: 281-92. PMID 14636556 |
0.466 |
|
| 2003 |
Buehr M, Smith A. Genesis of embryonic stem cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 358: 1397-402; discussion. PMID 14511487 DOI: 10.1098/rstb.2003.1327 |
0.564 |
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| 2003 |
Aubert J, Stavridis MP, Tweedie S, O'Reilly M, Vierlinger K, Li M, Ghazal P, Pratt T, Mason JO, Roy D, Smith A. Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 11836-11841. PMID 12923295 DOI: 10.1073/Pnas.1734197100 |
0.444 |
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| 2003 |
Chambers I, Colby D, Robertson M, Nichols J, Lee S, Tweedie S, Smith A. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell. 113: 643-55. PMID 12787505 |
0.564 |
|
| 2003 |
Medvinsky A, Smith A. Stem cells: Fusion brings down barriers. Nature. 422: 823-5. PMID 12712184 DOI: 10.1038/422823a |
0.51 |
|
| 2003 |
Ying QL, Stavridis M, Griffiths D, Li M, Smith A. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nature Biotechnology. 21: 183-6. PMID 12524553 DOI: 10.1038/Nbt780 |
0.545 |
|
| 2003 |
Burdon T, Smith A, Savatier P. Signalling, cell cycle and pluripotency in embryonic stem cells. Trends in Cell Biology. 12: 432-8. PMID 12220864 DOI: 10.1016/s0962-8924(02)02352-8 |
0.486 |
|
| 2002 |
Aubert J, Dunstan H, Chambers I, Smith A. Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation. Nature Biotechnology. 20: 1240-5. PMID 12447396 DOI: 10.1038/nbt763 |
0.534 |
|
| 2002 |
Billon N, Jolicoeur C, Ying QL, Smith A, Raff M. Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells. Journal of Cell Science. 115: 3657-65. PMID 12186951 DOI: 10.1242/jcs.00049 |
0.544 |
|
| 2002 |
Ying QL, Nichols J, Evans EP, Smith AG. Changing potency by spontaneous fusion. Nature. 416: 545-8. PMID 11932748 DOI: 10.1038/Nature729 |
0.596 |
|
| 2002 |
Niwa H, Masui S, Chambers I, Smith AG, Miyazaki J. Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells. Molecular and Cellular Biology. 22: 1526-36. PMID 11839818 |
0.459 |
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