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Karen J. Tonsfeldt, Ph.D. - Publications

Affiliations: 
Reproductive Medicine University of California, San Diego, La Jolla, CA 
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Van Loh BM, Yaw AM, Breuer JA, Jackson B, Nguyen D, Jang K, Ramos F, Ho EV, Cui LJ, Gillette DLM, Sempere LF, Gorman MR, Tonsfeldt KJ, Mellon PL, Hoffmann HM. The transcription factor VAX1 in VIP neurons of the suprachiasmatic nucleus impacts circadian rhythm generation, depressive-like behavior, and the reproductive axis in a sex-specific manner in mice. Frontiers in Endocrinology. 14: 1269672. PMID 38205198 DOI: 10.3389/fendo.2023.1269672  0.65
2023 Cassin J, Stamou MI, Keefe KW, Sung K, Bojo C, Tonsfeldt KJ, Rojas RA, Ferreira Lopes V, Plummer L, Salnikov KB, Keefe DL, Ozata M, Genel M, Georgopoulos NA, Hall JE, et al. Heterozygous mutations in SOX2 may cause idiopathic hypogonadotropic hypogonadism via dominant-negative mechanisms. Jci Insight. PMID 36602867 DOI: 10.1172/jci.insight.164324  0.491
2022 Tonsfeldt KJ, Cui LJ, Lee J, Walbeek TJ, Brusman LE, Jin Y, Mieda M, Gorman MR, Mellon PL. Female fertility does not require in suprachiasmatic nucleus neurons expressing arginine vasopressin, vasoactive intestinal peptide, or neuromedin-S. Frontiers in Endocrinology. 13: 956169. PMID 35992114 DOI: 10.3389/fendo.2022.956169  0.653
2022 Lavalle SN, Chou T, Hernandez J, Naing NCP, He MY, Tonsfeldt KJ, Mellon PL. Deletion of the homeodomain gene Six3 from kisspeptin neurons causes subfertility in female mice. Molecular and Cellular Endocrinology. 546: 111577. PMID 35121076 DOI: 10.1016/j.mce.2022.111577  0.624
2021 Tonsfeldt KJ, Mellon PL, Hoffmann HM. Circadian Rhythms in the Neuronal Network Timing the Luteinizing Hormone Surge. Endocrinology. PMID 34967900 DOI: 10.1210/endocr/bqab268  0.585
2021 Ho EV, Shi C, Cassin J, He MY, Nguyen RD, Ryan GE, Tonsfeldt KJ, Mellon PL. Reproductive Deficits Induced by Prenatal Anti-Mullerian Hormone Exposure Require Androgen Receptor in Kisspeptin Cells. Endocrinology. PMID 34529765 DOI: 10.1210/endocr/bqab197  0.581
2021 Hoffmann HM, Meadows JD, Breuer JA, Yaw AM, Nguyen D, Tonsfeldt KJ, Chin AY, Devries BM, Trang C, Oosterhouse HJ, Lee JS, Doser JW, Gorman MR, Welsh DK, Mellon PL. The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice. Journal of Neuroscience Research. PMID 34212416 DOI: 10.1002/jnr.24864  0.639
2021 Lavalle SN, Chou T, Hernandez J, Naing NCP, Tonsfeldt KJ, Hoffmann HM, Mellon PL. Kiss1 is differentially regulated in male and female mice by the homeodomain transcription factor VAX1. Molecular and Cellular Endocrinology. 111358. PMID 34098016 DOI: 10.1016/j.mce.2021.111358  0.635
2021 Schoeller EL, Tonsfeldt KJ, Sinkovich M, Shi R, Mellon PL. Growth Hormone Pulses and Liver Gene Expression are Differentially Regulated by the Circadian Clock Gene Bmal1. Endocrinology. PMID 33539533 DOI: 10.1210/endocr/bqab023  0.548
2020 Nicholas DA, Knight VS, Tonsfeldt KJ, Terasaka T, Molinar-Inglis O, Stephens SBZ, Trejo J, Kauffman AS, Mellon PL, Lawson MA. GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes. Scientific Reports. 10: 13063. PMID 32747664 DOI: 10.1038/S41598-020-69913-Z  0.664
2020 Nicholas D, Knight V, Tonsfeldt K, Terasaka T, Molinar-Inglis O, Stephens SBZ, Trejo J, Kauffman AS, Mellon PL, Lawson MA. MON-009 GLUT1-Mediated Glycolysis Facilitates GnRH-Induced Secretion of Luteinizing Hormone Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1694  0.612
2019 Pandolfi EC, Tonsfeldt KJ, Hoffmann HM, Mellon PL. Deletion of the Homeodomain Protein Six6 from GnRH Neurons Decreases GnRH Gene Expression Resulting in Infertility. Endocrinology. PMID 31211355 DOI: 10.1210/En.2019-00113  0.661
2019 Tonsfeldt KJ, Schoeller EL, Brusman LE, Cui LJ, Lee J, Mellon PL. The Contribution of the Circadian Gene to Female Fertility and the Generation of the Preovulatory Luteinizing Hormone Surge. Journal of the Endocrine Society. 3: 716-733. PMID 30906911 DOI: 10.1210/Js.2018-00228  0.722
2019 Tonsfeldt K, Cui L, Mellon P. SUN-473 The Contribution of Bmal1 Expression in the Suprachiasmatic Nucleus to Female Fertility Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sun-473  0.581
2016 Tonsfeldt KJ, Suchland KL, Beeson KA, Lowe JD, Li MH, Ingram SL. Sex Differences in GABAA Signaling in the Periaqueductal Gray Induced by Persistent Inflammation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1669-81. PMID 26843648 DOI: 10.1523/Jneurosci.1928-15.2016  0.62
2013 Zhang C, Tonsfeldt KJ, Qiu J, Bosch MA, Kobayashi K, Steiner RA, Kelly MJ, Rønnekleiv OK. Molecular mechanisms that drive estradiol-dependent burst firing of Kiss1 neurons in the rostral periventricular preoptic area. American Journal of Physiology. Endocrinology and Metabolism. 305: E1384-97. PMID 24105416 DOI: 10.1152/Ajpendo.00406.2013  0.487
2013 Bosch MA, Tonsfeldt KJ, Rønnekleiv OK. mRNA expression of ion channels in GnRH neurons: subtype-specific regulation by 17β-estradiol. Molecular and Cellular Endocrinology. 367: 85-97. PMID 23305677 DOI: 10.1016/J.Mce.2012.12.021  0.415
2012 Tonsfeldt KJ, Chappell PE. Clocks on top: the role of the circadian clock in the hypothalamic and pituitary regulation of endocrine physiology. Molecular and Cellular Endocrinology. 349: 3-12. PMID 21787834 DOI: 10.1016/J.Mce.2011.07.003  0.7
2011 Gottsch ML, Popa SM, Lawhorn JK, Qiu J, Tonsfeldt KJ, Bosch MA, Kelly MJ, Rønnekleiv OK, Sanz E, McKnight GS, Clifton DK, Palmiter RD, Steiner RA. Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouse. Endocrinology. 152: 4298-309. PMID 21933870 DOI: 10.1210/En.2011-1521  0.518
2011 Tonsfeldt KJ, Goodall CP, Latham KL, Chappell PE. Oestrogen induces rhythmic expression of the Kisspeptin-1 receptor GPR54 in hypothalamic gonadotrophin-releasing hormone-secreting GT1-7 cells. Journal of Neuroendocrinology. 23: 823-30. PMID 21756268 DOI: 10.1111/J.1365-2826.2011.02188.X  0.747
2011 Tonsfeldt K, Qiu J, Gottsch ML, Clifton DK, Steiner RA, Kelly MJ, Ronnekleiv OK. Kisspeptin Neurons in the Anteroventral Periventricular Nucleus as Temporal Gate-Keepers to the Preovulatory Gonadotropin-Releasing Hormone Surge. Biology of Reproduction. 85: 610-610. DOI: 10.1093/Biolreprod/85.S1.610  0.509
2011 Tolson KP, Tonsfeldt K, Goodall C, Palermini A, Chappell PE. Disruption of Endogenous Circadian Clocks in Immortalized GT1-7 Cells Blocks Estrogen Positive Feedback-Stimulated GnRH Secretion In Vitro. Biology of Reproduction. 85: 192-192. DOI: 10.1093/Biolreprod/85.S1.192  0.689
2009 Chappell PE, Goodall CP, Tonsfeldt KJ, White RS, Bredeweg E, Latham KL. Modulation of gonadotrophin-releasing hormone secretion by an endogenous circadian clock. Journal of Neuroendocrinology. 21: 339-45. PMID 19187466 DOI: 10.1111/J.1365-2826.2009.01845.X  0.745
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