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Doug E. Frantz, Ph.D. - Publications

Affiliations: 
Chemistry The University of Texas at San Antonio, San Antonio, TX, United States 
Area:
Practical Synthetic Methodology
Website:
http://www.utsa.edu/chem/faculty/dougfrantz/Frantz_Research_Group/Home.html
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Munteanu C, Spiller TE, Qiu J, DelMonte AJ, Wisniewski SR, Simmons EM, Frantz DE. Pd- and Ni-Based Systems for the Catalytic Borylation of Aryl (Pseudo)Halides with B2(OH)4. The Journal of Organic Chemistry. PMID 32662636 DOI: 10.1021/Acs.Joc.0C00929  0.364
2018 Neff RK, Frantz DE. The Cationic Alkynyl Heck Reaction Towards Substituted Allenes Using BobCat: A New Hybrid Pd(0)-Catalyst Incorporating a Water-Soluble dba Ligand. Journal of the American Chemical Society. PMID 30521312 DOI: 10.1021/Jacs.8B11759  0.392
2018 Stevens JM, Parra-Rivera AC, Dixon DD, Beutner GL, DelMonte AJ, Frantz DE, Janey JM, Paulson J, Talley MR. Direct Lewis Acid-Catalyzed Conversion of Enantioenriched N-Acyl Oxazolidinones to Chiral Esters, Amides, and Acids. The Journal of Organic Chemistry. PMID 30412670 DOI: 10.1021/Acs.Joc.8B02451  0.338
2018 El Arba M, Dibrell SE, Meece F, Frantz DE. Ru(II)-Catalyzed Synthesis of Substituted Furans and Their Conversion to Butenolides. Organic Letters. 20: 5886-5888. PMID 30204453 DOI: 10.1021/Acs.Orglett.8B02554  0.416
2017 El Arba M, Dibrell SE, Crouch IT, Frantz DE. Unified Approach to Substituted Allenoates via Pd-Catalyzed β-Hydride Elimination of (E)-Enol Triflates. Organic Letters. PMID 28953409 DOI: 10.1021/Acs.Orglett.7B02736  0.752
2016 Munteanu C, Frantz DE. Palladium-Catalyzed Synthesis of Alkynes via a Tandem Decarboxylation/Elimination of (E)-Enol Triflates. Organic Letters. PMID 27456435 DOI: 10.1021/Acs.Orglett.6B01904  0.445
2016 Rivera AC, Still R, Frantz DE. Iron-Catalyzed Stereoselective Cross-Coupling Reactions of Stereodefined Enol Carbamates with Grignard Reagents. Angewandte Chemie (International Ed. in English). PMID 27088754 DOI: 10.1002/Anie.201601899  0.368
2015 Neff RK, Frantz DE. Recent applications of chiral allenes in axial-to-central chirality transfer reactions Tetrahedron. 71: 7-18. DOI: 10.1016/J.Tet.2014.08.030  0.329
2014 Neff RK, Frantz DE. Recent advances in the catalytic syntheses of allenes: A critical assessment Acs Catalysis. 4: 519-528. DOI: 10.1021/Cs401007M  0.379
2013 Valentim CL, Cioli D, Chevalier FD, Cao X, Taylor AB, Holloway SP, Pica-Mattoccia L, Guidi A, Basso A, Tsai IJ, Berriman M, Carvalho-Queiroz C, Almeida M, Aguilar H, Frantz DE, et al. Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites. Science (New York, N.Y.). 342: 1385-9. PMID 24263136 DOI: 10.1126/Science.1243106  0.685
2013 Risinger AL, Peng J, Rohena CC, Aguilar HR, Frantz DE, Mooberry SL. The bat flower: a source of microtubule-destabilizing and -stabilizing compounds with synergistic antiproliferative actions. Journal of Natural Products. 76: 1923-9. PMID 24087857 DOI: 10.1021/Np4005079  0.696
2013 Wang L, Chang J, Varghese D, Dellinger M, Kumar S, Best AM, Ruiz J, Bruick R, Peña-Llopis S, Xu J, Babinski DJ, Frantz DE, Brekken RA, Quinn AM, Simeonov A, et al. A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nature Communications. 4: 2035. PMID 23792809 DOI: 10.1038/Ncomms3035  0.724
2013 Crouch IT, Neff RK, Frantz DE. Pd-catalyzed asymmetric β-hydride elimination en route to chiral allenes. Journal of the American Chemical Society. 135: 4970-3. PMID 23488914 DOI: 10.1021/Ja401606E  0.758
2013 Wang L, Chang J, Varghese D, Dellinger M, Kumar S, Best AM, Ruiz J, Bruick R, Penã-Llopis S, Xu J, Babinski DJ, Frantz DE, Brekken RA, Quinn AM, Simeonov A, et al. Erratum: A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth Nature Communications. 4. DOI: 10.1038/Ncomms3639  0.713
2012 Babinski DJ, Bao X, El Arba M, Chen B, Hrovat DA, Borden WT, Frantz DE. Synchronized aromaticity as an enthalpic driving force for the aromatic Cope rearrangement. Journal of the American Chemical Society. 134: 16139-42. PMID 22963196 DOI: 10.1021/Ja307213M  0.74
2012 Russell JL, Goetsch SC, Aguilar HR, Coe H, Luo X, Liu N, van Rooij E, Frantz DE, Schneider JW. Regulated expression of pH sensing G Protein-coupled receptor-68 identified through chemical biology defines a new drug target for ischemic heart disease. Acs Chemical Biology. 7: 1077-83. PMID 22462679 DOI: 10.1021/Cb300001M  0.698
2012 Russell JL, Goetsch SC, Aguilar HR, Frantz DE, Schneider JW. Targeting native adult heart progenitors with cardiogenic small molecules. Acs Chemical Biology. 7: 1067-76. PMID 22413910 DOI: 10.1021/Cb200525Q  0.698
2011 Babinski DJ, Aguilar HR, Still R, Frantz DE. Synthesis of substituted pyrazoles via tandem cross-coupling/electrocyclization of enol triflates and diazoacetates. The Journal of Organic Chemistry. 76: 5915-23. PMID 21682322 DOI: 10.1021/Jo201042C  0.745
2011 Crouch IT, Dreier T, Frantz DE. Palladium-catalyzed elimination/isomerization of enol triflates into 1,3-dienes. Angewandte Chemie (International Ed. in English). 50: 6128-32. PMID 21574234 DOI: 10.1002/Anie.201101820  0.765
2011 Zhang L, Li P, Hsu T, Aguilar HR, Frantz DE, Schneider JW, Bachoo RM, Hsieh J. Small-molecule blocks malignant astrocyte proliferation and induces neuronal gene expression. Differentiation; Research in Biological Diversity. 81: 233-42. PMID 21419563 DOI: 10.1016/J.Diff.2011.02.005  0.695
2011 Carreira EM, Frantz DE. ChemInform Abstract: Enantioselective Addition of Acetylide Nucleophiles to Carbonyl Compounds Cheminform. 42: no-no. DOI: 10.1002/chin.201140208  0.363
2010 Peng J, Jackson EM, Babinski DJ, Risinger AL, Helms G, Frantz DE, Mooberry SL. Evelynin, a cytotoxic benzoquinone-type Retro-dihydrochalcone from Tacca chantrieri. Journal of Natural Products. 73: 1590-2. PMID 20715765 DOI: 10.1021/Np100350S  0.718
2010 Faessler R, Frantz DE, Oetiker J, Carreira EM. ChemInform Abstract: First Synthesis of Optically Pure Propargylic N-Hydroxylamines by Direct, Highly Diastereoselective Addition of Terminal Alkynes to Nitrones. Cheminform. 33: no-no. DOI: 10.1002/chin.200251086  0.365
2010 Frantz DE, Faessler R, Tomooka CS, Carreira EM. ChemInform Abstract: The Discovery of Novel Reactivity in the Development of C-C Bond-Forming Reactions: In situ Generation of Zinc Acetylides with ZnII/R3N Cheminform. 31: no-no. DOI: 10.1002/chin.200036268  0.352
2010 Frantz DE, Faessler R, Carreira EM. ChemInform Abstract: Facile Enantioselective Synthesis of Propargylic Alcohols by Direct Addition of Terminal Alkynes to Aldehydes. Cheminform. 31: no-no. DOI: 10.1002/chin.200021040  0.366
2010 Frantz DE, Faessler R, Carreira EM. ChemInform Abstract: Catalytic in situ Generation of Zn(II)-Alkynilides under Mild Conditions: A Novel C=N Addition Process Utilizing Terminal Acetylenes. Cheminform. 31: no-no. DOI: 10.1002/chin.200010076  0.339
2009 Menzel K, Machrouhi F, Bodenstein M, Alorati A, Cowden C, Gibson AW, Bishop B, Ikemoto N, Nelson TD, Kress MH, Frantz DE. Process development of a potent bradykinin 1 antagonist Organic Process Research and Development. 13: 519-524. DOI: 10.1021/Op8003184  0.423
2008 Babinski D, Soltani O, Frantz DE. Stereoselective synthesis of acetoacetate-derived enol triflates. Organic Letters. 10: 2901-4. PMID 18540630 DOI: 10.1021/Ol8010002  0.753
2008 Menzel K, Mills PM, Frantz DE, Nelson TD, Kress MH. Substitution effect on the regioselective halogen/metal exchange of 3-substituted 1,2,5-tribromobenzenes Tetrahedron Letters. 49: 415-418. DOI: 10.1016/J.Tetlet.2007.11.124  0.312
2006 DiMichele L, Menzel K, Mills P, Frantz D, Nelson T. Halogen-metal exchange of 3-substituted 1,2-dibromoarenes: The use of long-range JCH coupling constants to determine regiochemistry Magnetic Resonance in Chemistry. 44: 1041-1043. PMID 16941579 DOI: 10.1002/Mrc.1891  0.312
2006 Menzel K, Fisher EL, Dimichele L, Frantz DE, Nelson TD, Kress MH. An improved method for the bromination of metalated haloarenes via lithium, zinc transmetalation: a convenient synthesis of 1,2-dibromoarenes. The Journal of Organic Chemistry. 71: 2188-91. PMID 16497017 DOI: 10.1021/Jo052515K  0.357
2006 Menzel K, Dimichele L, Mills P, Frantz DE, Nelson TD, Kress MH. Regioselective halogen-metal exchange reaction of 3-substituted 1,2-dibromo arenes: The synthesis of 2-substituted 5-bromobenzoic acids Synlett. 1948-1952. DOI: 10.1055/S-2006-947362  0.35
2004 Nelson TD, LeBlond CR, Frantz DE, Matty L, Mitten JV, Weaver DG, Moore JC, Kim JM, Boyd R, Kim PY, Gbewonyo K, Brower M, Sturr M, McLaughlin K, McMasters DR, et al. Stereoselective synthesis of a potent thrombin inhibitor by a novel P2-P3 lactone ring opening. The Journal of Organic Chemistry. 69: 3620-7. PMID 15152989 DOI: 10.1021/Jo035794P  0.383
2004 Fässler R, Tomooka CS, Frantz DE, Carreira EM. Infrared spectroscopic investigations on the metallation of terminal alkynes by Zn(OTf)2. Proceedings of the National Academy of Sciences of the United States of America. 101: 5843-5. PMID 15067111 DOI: 10.1073/Pnas.0308326101  0.388
2004 Frantz DE, Morency L, Soheili A, Murry JA, Grabowski EJ, Tillyer RD. Synthesis of substituted imidazoles via organocatalysis. Organic Letters. 6: 843-6. PMID 14986989 DOI: 10.1021/Ol0498803  0.407
2002 Frantz DE, Weaver DG, Carey JP, Kress MH, Dolling UH. Practical synthesis of aryl triflates under aqueous conditions. Organic Letters. 4: 4717-8. PMID 12489969 DOI: 10.1021/Ol027154Z  0.362
2002 Fässler R, Frantz DE, Oetiker J, Carreira EM. First synthesis of optically pure propargylic N-hydroxylamines by direct, highly diastereoselective addition of terminal alkynes to nitrones. Angewandte Chemie (International Ed. in English). 41: 3054-6. PMID 12203456 DOI: 10.1002/1521-3773(20020816)41:16<3054::Aid-Anie3054>3.0.Co;2-B  0.442
2002 Boyall D, Frantz DE, Carreira EM. Efficient enantioselective additions of terminal alkynes and aldehydes under operationally convenient conditions. Organic Letters. 4: 2605-6. PMID 12123387 DOI: 10.1021/Ol026282K  0.505
2002 Fässler R, Frantz DE, Oetiker J, Carreira EM. First Synthesis of Optically Pure Propargylic N-Hydroxylamines by Direct, Highly Diastereoselective Addition of Terminal Alkynes to Nitrones We thank the ETH, Roche Research Foundation, the Swiss National Science Foundation, Merck, and Aventis for their generous support. Angewandte Chemie. 114: 3180. DOI: 10.1002/1521-3757(20020816)114:16<3180::Aid-Ange3180>3.0.Co;2-L  0.426
2001 Murry JA, Frantz DE, Soheili A, Tillyer R, Grabowski EJ, Reider PJ. Synthesis of alpha-amido ketones via organic catalysis: thiazolium-catalyzed cross-coupling of aldehydes with acylimines. Journal of the American Chemical Society. 123: 9696-7. PMID 11572700 DOI: 10.1021/Ja0165943  0.336
2001 Frey LF, Marcantonio K, Frantz DE, Murry JA, Tillyer RD, Grabowski EJJ, Reider PJ. Practical routes toward the synthesis of 2-halo- and 2-alkylamino-4-pyridinecarboxaldehydes Tetrahedron Letters. 42: 6815-6818. DOI: 10.1016/S0040-4039(01)01428-9  0.324
2000 Boyall D, López F, Sasaki H, Frantz D, Carreira EM. Enantioselective addition of 2-methyl-3-butyn-2-ol to aldehydes: preparation of 3-hydroxy-1-butynes Organic Letters. 2: 4233-4236. PMID 11150207 DOI: 10.1021/Ol006791R  0.509
2000 Aschwanden P, Frantz DE, Carreira EM. Synthesis of 2,3-dihydroisoxazoles from propargylic N-hydroxylamines via Zn(II)-catalyzed ring-closure reaction Organic Letters. 2: 2331-3. PMID 10930276 DOI: 10.1021/Ol006095R  0.497
2000 Frantz DE, Fassler R, Tomooka CS, Carreira EM. The discovery of novel reactivity in the development of C-C bond-forming reactions: in situ generation of zinc acetylides with Zn(II)/R(3)N. Accounts of Chemical Research. 33: 373-81. PMID 10891055 DOI: 10.1021/Ar990078O  0.474
2000 Frantz DE, Fässler R, Carreira EM. Facile enantioselective synthesis of propargylic alcohols by direct addition of terminal alkynes to aldehydes [3] Journal of the American Chemical Society. 122: 1806-1807. DOI: 10.1021/Ja993838Z  0.442
2000 Frantz DE, Singleton DA. Isotope effects and the mechanism of chlorotrimethylsilane-mediated addition of cuprates to enones Journal of the American Chemical Society. 122: 3288-3295. DOI: 10.1021/Ja993373C  0.588
1999 Frantz DE, Singleton DA. Carbometalations of simple alkenes with allyldibromoborane Organic Letters. 1: 485-486. PMID 10822588 DOI: 10.1021/Ol990673Q  0.63
1999 Frantz DE, Fässler R, Carreira EM. Catalytic in situ generation of Zn(II)-alkynilides under mild conditions: A novel C=N addition process utilizing terminal acetylenes [12] Journal of the American Chemical Society. 121: 11245-11246. DOI: 10.1021/Ja993074N  0.418
1997 Frantz DE, Singleton DA, Snyder JP. 13C kinetic isotope effects for the addition of lithium dibutylcuprate to cyclohexenone. Reductive elimination is rate-determining Journal of the American Chemical Society. 119: 3383-3384. DOI: 10.1021/Ja9636348  0.556
1996 Singleton DA, Waller SC, Zhang Z, Frantz DE, Leung SW. Allylboration of alkenes with allyldihaloboranes Journal of the American Chemical Society. 118: 9986-9987. DOI: 10.1021/Ja961616K  0.634
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