Sanja Sever, Ph.D. - Publications

Affiliations: 
Massachusetts General Hospital, Boston, MA 

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhu K, Mukherjee K, Wei C, Hayek SS, Collins A, Gu C, Corapi K, Altintas MM, Wang Y, Waikar SS, Bianco AC, Koch A, Tacke F, Reiser J, Sever S. The D2D3 form of uPAR acts as an immunotoxin and may cause diabetes and kidney disease. Science Translational Medicine. 15: eabq6492. PMID 37729431 DOI: 10.1126/scitranslmed.abq6492  0.428
2022 Mukherjee K, Gu C, Collins A, Mettlen M, Samelko B, Altintas MM, Sudhini YR, Wang X, Bouley R, Brown D, Pedro BP, Bane SL, Gupta V, Brinkkoetter PT, Hagmann H, ... ... Sever S, et al. Simultaneous stabilization of actin cytoskeleton in multiple nephron-specific cells protects the kidney from diverse injury. Nature Communications. 13: 2422. PMID 35504916 DOI: 10.1038/s41467-022-30101-4  0.485
2020 Sever S. Role of actin cytoskeleton in podocytes. Pediatric Nephrology (Berlin, Germany). PMID 33188449 DOI: 10.1007/s00467-020-04812-z  0.328
2020 Hayek SS, Leaf DE, Samman Tahhan A, Raad M, Sharma S, Waikar SS, Sever S, Camacho A, Wang X, Dande RR, Ibrahim NE, Baron RM, Altintas MM, Wei C, Sheikh-Hamad D, et al. Soluble Urokinase Receptor and Acute Kidney Injury. The New England Journal of Medicine. 382: 416-426. PMID 31995687 DOI: 10.1056/Nejmoa1911481  0.32
2019 Wei C, Li J, Adair BD, Zhu K, Cai J, Merchant M, Samelko B, Liao Z, Koh KH, Tardi NJ, Dande RR, Liu S, Ma J, DiBartolo S, Hägele S, ... ... Sever S, et al. uPAR isoform 2 forms a dimer and induces severe kidney disease in mice. The Journal of Clinical Investigation. PMID 30730305 DOI: 10.1172/Jci124793  0.368
2018 Sever S, Schiffer M. Actin dynamics at focal adhesions: a common endpoint and putative therapeutic target for proteinuric kidney diseases. Kidney International. PMID 29678354 DOI: 10.1016/J.Kint.2017.12.028  0.44
2017 Hayek SS, Ko YA, Awad M, Ahmed H, Gray B, Hosny KM, Aida H, Tracy MJ, Wei C, Sever S, Reiser J, Quyyumi AA. Cardiovascular Disease Biomarkers and suPAR in Predicting Decline in Renal Function: A Prospective Cohort Study. Kidney International Reports. 2: 425-432. PMID 29142970 DOI: 10.1016/J.Ekir.2017.02.001  0.31
2017 Sever S, Gu C. Podocytes and the actin cytoskeleton as a feasible therapeutic target Periodicum Biologorum. 118: 381-384. DOI: 10.18054/Pb.V118I4.4576  0.371
2016 Hahm E, Wei C, Fernandez I, Li J, Tardi NJ, Tracy M, Wadhwani S, Cao Y, Peev V, Zloza A, Lusciks J, Hayek SS, O'Connor C, Bitzer M, Gupta V, ... Sever S, et al. Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease. Nature Medicine. PMID 27941791 DOI: 10.1038/Nm.4242  0.372
2016 Lee H, Noh H, Mun J, Gu C, Sever S, Park S. Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis. Nature Communications. 7: 12799. PMID 27619642 DOI: 10.1038/Ncomms12799  0.492
2016 Gu C, Lee HW, Garborcauskas G, Reiser J, Gupta V, Sever S. Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation. Journal of the American Society of Nephrology : Jasn. PMID 27432739 DOI: 10.1681/Asn.2016010008  0.56
2015 Hayek SS, Sever S, Ko YA, Trachtman H, Awad M, Wadhwani S, Altintas MM, Wei C, Hotton AL, French AL, Sperling LS, Lerakis S, Quyyumi AA, Reiser J. Soluble Urokinase Receptor and Chronic Kidney Disease. The New England Journal of Medicine. 373: 1916-25. PMID 26539835 DOI: 10.1056/Nejmoa1506362  0.324
2015 Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, ... ... Sever S, et al. Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nature Medicine. 21: 601-9. PMID 25962121 DOI: 10.1038/Nm.3843  0.723
2015 Lee HW, Khan SQ, Faridi MH, Wei C, Tardi NJ, Altintas MM, Elshabrawy HA, Mangos S, Quick KL, Sever S, Reiser J, Gupta V. A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules. Journal of the American Society of Nephrology : Jasn. PMID 25858967 DOI: 10.1681/Asn.2014090859  0.31
2014 Trachtman H, Benzing T, Sever S, Harris RC, Reiser J. The grand challenge of nephrology. Frontiers in Medicine. 1: 28. PMID 25593903 DOI: 10.3389/Fmed.2014.00028  0.332
2014 Gu C, Chang J, Shchedrina VA, Pham VA, Hartwig JH, Suphamungmee W, Lehman W, Hyman BT, Bacskai BJ, Sever S. Regulation of dynamin oligomerization in cells: the role of dynamin-actin interactions and its GTPase activity. Traffic (Copenhagen, Denmark). 15: 819-38. PMID 24891099 DOI: 10.1111/Tra.12178  0.723
2014 Altintas MM, Moriwaki K, Wei C, Möller CC, Flesche J, Li J, Yaddanapudi S, Faridi MH, Gödel M, Huber TB, Preston RA, Jiang JX, Kerjaschki D, Sever S, Reiser J. Reduction of proteinuria through podocyte alkalinization. The Journal of Biological Chemistry. 289: 17454-67. PMID 24817115 DOI: 10.1074/Jbc.M114.568998  0.345
2013 Kistler AD, Singh G, Altintas MM, Yu H, Fernandez IC, Gu C, Wilson C, Srivastava SK, Dietrich A, Walz K, Kerjaschki D, Ruiz P, Dryer S, Sever S, Dinda AK, et al. Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease. The Journal of Biological Chemistry. 288: 36598-609. PMID 24194522 DOI: 10.1074/Jbc.M113.488122  0.536
2013 Sever S, Chang J, Gu C. Dynamin rings: not just for fission. Traffic (Copenhagen, Denmark). 14: 1194-9. PMID 23980695 DOI: 10.1111/Tra.12116  0.565
2013 Reiser J, Sever S. Podocyte biology and pathogenesis of kidney disease. Annual Review of Medicine. 64: 357-66. PMID 23190150 DOI: 10.1146/Annurev-Med-050311-163340  0.366
2012 Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst AL, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, ... ... Sever S, et al. CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival (The Journal of Clinical Investigation (2011) 121, 10, (3965-3980) DOI: 10.1172/JCI58552) Journal of Clinical Investigation. 122: 780. DOI: 10.1172/Jci62812  0.454
2012 Rayego-Mateos S, Rodrigues-Díez R, Rodrigues-Díez RR, Lavoz-Barria C, Alique M, Mas S, Pato J, Keri G, Egido J, Ortiz A, Ruiz-Ortega M, Ying L, Tepel M, Frank E, Florian T, ... ... Sever S, et al. Mechanisms and targets of glomerular damage Nephrology Dialysis Transplantation. 27. DOI: 10.1093/Ndt/Gfs229  0.437
2011 Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst AL, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, ... ... Sever S, et al. CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival. The Journal of Clinical Investigation. 121: 3965-80. PMID 21911934 DOI: 10.1172/Jci58552  0.56
2010 Gu C, Yaddanapudi S, Weins A, Osborn T, Reiser J, Pollak M, Hartwig J, Sever S. Direct dynamin-actin interactions regulate the actin cytoskeleton. The Embo Journal. 29: 3593-606. PMID 20935625 DOI: 10.1038/Emboj.2010.249  0.557
2010 Chiang WC, Geel TM, Altintas MM, Sever S, Ruiters MH, Reiser J. Establishment of protein delivery systems targeting podocytes. Plos One. 5: e11837. PMID 20686602 DOI: 10.1371/Journal.Pone.0011837  0.36
2010 Colvin RA, Means TK, Diefenbach TJ, Moita LF, Friday RP, Sever S, Campanella GS, Abrazinski T, Manice LA, Moita C, Andrews NW, Wu D, Hacohen N, Luster AD. Synaptotagmin-mediated vesicle fusion regulates cell migration. Nature Immunology. 11: 495-502. PMID 20473299 DOI: 10.1038/Ni.1878  0.331
2009 Adair BD, Altintas M, Möller CC, Flesche J, Wei C, Faul C, Campbell K, Gu C, Sever S, Shaw A, Mundel P, Reiser J. CD2AP Structure And Progression Of Renal Disease Biophysical Journal. 96: 132a-133a. DOI: 10.1016/J.Bpj.2008.12.601  0.539
2007 Sever S, Altintas MM, Nankoe SR, Möller CC, Ko D, Wei C, Henderson J, del Re EC, Hsing L, Erickson A, Cohen CD, Kretzler M, Kerjaschki D, Rudensky A, Nikolic B, et al. Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease. The Journal of Clinical Investigation. 117: 2095-104. PMID 17671649 DOI: 10.1172/Jci32022  0.379
2006 Nankoe SR, Sever S. Dynasore puts a new spin on dynamin: a surprising dual role during vesicle formation. Trends in Cell Biology. 16: 607-9. PMID 17064900 DOI: 10.1016/J.Tcb.2006.10.004  0.325
2006 Sever S, Skoch J, Newmyer S, Ramachandran R, Ko D, McKee M, Bouley R, Ausiello D, Hyman BT, Bacskai BJ. Physical and functional connection between auxilin and dynamin during endocytosis. The Embo Journal. 25: 4163-74. PMID 16946707 DOI: 10.1038/Sj.Emboj.7601298  0.393
2005 Sever S, Skoch J, Bacskai BJ, Newmyer SL. Assays and functional properties of auxilin-dynamin interactions. Methods in Enzymology. 404: 570-85. PMID 16413301 DOI: 10.1016/S0076-6879(05)04050-4  0.346
2003 Sever S. AP-2 makes room for rivals. Developmental Cell. 5: 530-2. PMID 14536052 DOI: 10.1016/S1534-5807(03)00304-6  0.312
2003 Newmyer SL, Christensen A, Sever S. Auxilin-dynamin interactions link the uncoating ATPase chaperone machinery with vesicle formation. Developmental Cell. 4: 929-40. PMID 12791276 DOI: 10.1016/S1534-5807(03)00157-6  0.368
2002 Sever S. Dynamin and endocytosis. Current Opinion in Cell Biology. 14: 463-7. PMID 12383797 DOI: 10.1016/S0955-0674(02)00347-2  0.358
2001 Damke H, Muhlberg AB, Sever S, Sholly S, Warnock DE, Schmid SL. Expression, purification, and functional assays for self-association of dynamin-1. Methods in Enzymology. 329: 447-57. PMID 11210565 DOI: 10.1016/S0076-6879(01)29106-X  0.639
2000 Sever S, Damke H, Schmid SL. Garrotes, springs, ratchets, and whips: putting dynamin models to the test. Traffic (Copenhagen, Denmark). 1: 385-92. PMID 11208124 DOI: 10.1034/J.1600-0854.2000.010503.X  0.501
2000 Sever S, Damke H, Schmid SL. Dynamin:GTP controls the formation of constricted coated pits, the rate limiting step in clathrin-mediated endocytosis. The Journal of Cell Biology. 150: 1137-48. PMID 10974001 DOI: 10.1083/Jcb.150.5.1137  0.541
1999 Ibba M, Sever S, Praetorius-Ibba M, Söll D. Transfer RNA identity contributes to transition state stabilization during aminoacyl-tRNA synthesis. Nucleic Acids Research. 27: 3631-7. PMID 10471730 DOI: 10.1093/Nar/27.18.3631  0.426
1999 Sever S, Muhlberg AB, Schmid SL. Impairment of dynamin's GAP domain stimulates receptor-mediated endocytosis. Nature. 398: 481-6. PMID 10206643 DOI: 10.1038/19024  0.552
1996 Ibba M, Hong KW, Sherman JM, Sever S, Söll D. Interactions between tRNA identity nucleotides and their recognition sites in glutaminyl-tRNA synthetase determine the cognate amino acid affinity of the enzyme. Proceedings of the National Academy of Sciences of the United States of America. 93: 6953-8. PMID 8692925 DOI: 10.1073/Pnas.93.14.6953  0.439
1996 Sever S, Rogers K, Rogers MJ, Carter C, Söll D. Escherichia coli tryptophanyl-tRNA synthetase mutants selected for tryptophan auxotrophy implicate the dimer interface in optimizing amino acid binding. Biochemistry. 35: 32-40. PMID 8555191 DOI: 10.1021/Bi952103D  0.461
1995 Ibba M, Thomann HU, Hong KW, Sherman JM, Weygand-Durasevic I, Sever S, Stange-Thomann N, Praetorius M, Söll D. Substrate selection by aminoacyl-tRNA synthetases. Nucleic Acids Symposium Series. 40-2. PMID 8643392  0.38
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