Srikant Rangaraju - Publications

Affiliations: 
Neurology Emory University, Atlanta, GA 

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kumar P, Goettemoeller AM, Espinosa-Garcia C, Tobin BR, Tfaily A, Nelson RS, Natu A, Dammer EB, Santiago JV, Malepati S, Cheng L, Xiao H, Duong DD, Seyfried NT, Wood LB, ... ... Rangaraju S, et al. Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology. Nature Communications. 15: 2823. PMID 38561349 DOI: 10.1038/s41467-024-47028-7  0.773
2024 Wojtas AM, Dammer EB, Guo Q, Ping L, Shantaraman A, Duong DM, Yin L, Fox EJ, Seifar F, Lee EB, Johnson ECB, Lah JJ, Levey AI, Levites Y, Rangaraju S, et al. Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. Medrxiv : the Preprint Server For Health Sciences. PMID 38260316 DOI: 10.1101/2024.01.10.24301099  0.795
2024 Wang E, Pan AL, Bagchi P, Rangaraju S, Seyfried NT, Ehrlich ME, Salton SR, Zhang B. Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease. Biomolecules. 14. PMID 38254666 DOI: 10.3390/biom14010066  0.535
2023 Rowan M, Goettemoeller A, Banks E, McCann K, Kumar P, South K, Olah V, Ramelow C, Duong D, Seyfried N, Rangaraju S, Weinshenker D. Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology. Research Square. PMID 37987015 DOI: 10.21203/rs.3.rs-3370607/v1  0.58
2023 Santiago JV, Natu A, Ramelow CC, Rayaprolu S, Xiao H, Kumar V, Kumar P, Seyfried NT, Rangaraju S. Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles. Molecular & Cellular Proteomics : McP. 100678. PMID 37952696 DOI: 10.1016/j.mcpro.2023.100678  0.563
2023 Santiago JV, Natu A, Ramelow CC, Rayaprolu S, Xiao H, Kumar V, Seyfried NT, Rangaraju S. Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles. Biorxiv : the Preprint Server For Biology. PMID 37546899 DOI: 10.1101/2023.07.28.551012  0.563
2023 Pybus AF, Bitarafan S, Brothers RO, Rohrer A, Khaitan A, Moctezuma FR, Udeshi K, Davies B, Triplett S, Dammer E, Rangaraju S, Buckley EM, Wood LB. Profiling the neuroimmune cascade in 3xTg mice exposed to successive mild traumatic brain injuries. Biorxiv : the Preprint Server For Biology. PMID 37397993 DOI: 10.1101/2023.06.13.544838  0.675
2023 Kumar P, Goettemoeller AM, Espinosa-Garcia C, Tobin BR, Tfaily A, Nelson RS, Natu A, Dammer EB, Santiago JV, Malepati S, Cheng L, Xiao H, Duong D, Seyfried NT, Wood LB, ... ... Rangaraju S, et al. Native-state proteomics of Parvalbumin interneurons identifies novel molecular signatures and metabolic vulnerabilities to early Alzheimer's disease pathology. Biorxiv : the Preprint Server For Biology. PMID 37292756 DOI: 10.1101/2023.05.17.541038  0.782
2023 Wynne ME, Ogunbona O, Lane AR, Gokhale A, Zlatic SA, Xu C, Wen Z, Duong DM, Rayaprolu S, Ivanova A, Ortlund EA, Dammer EB, Seyfried NT, Roberts BR, Crocker A, ... ... Rangaraju S, et al. APOE expression and secretion are modulated by mitochondrial dysfunction. Elife. 12. PMID 37171075 DOI: 10.7554/eLife.85779  0.759
2023 Sunna S, Bowen C, Zeng H, Rayaprolu S, Kumar P, Bagchi P, Dammer EB, Guo Q, Duong DM, Bitarafan S, Natu A, Wood L, Seyfried NT, Rangaraju S. Cellular proteomic profiling using proximity labelling by TurboID-NES in microglial and neuronal cell lines. Molecular & Cellular Proteomics : McP. 100546. PMID 37061046 DOI: 10.1016/j.mcpro.2023.100546  0.749
2023 Sunna S, Bowen CA, Ramelow CC, Santiago JV, Kumar P, Rangaraju S. Advances in proteomic phenotyping of microglia in neurodegeneration. Proteomics. e2200183. PMID 37060300 DOI: 10.1002/pmic.202200183  0.371
2022 Nelson RS, Dammer EB, Santiago JV, Seyfried NT, Rangaraju S. Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms. Frontiers in Neuroscience. 16: 902146. PMID 35784845 DOI: 10.3389/fnins.2022.902146  0.747
2022 Olah VJ, Goettemoeller AM, Rayaprolu S, Dammer EB, Seyfried NT, Rangaraju S, Dimidschstein J, Rowan MJM. Biophysical Kv3 channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer's. Elife. 11. PMID 35727131 DOI: 10.7554/eLife.75316  0.753
2022 Rayaprolu S, Bitarafan S, Santiago JV, Betarbet R, Sunna S, Cheng L, Xiao H, Nelson RS, Kumar P, Bagchi P, Duong DM, Goettemoeller AM, Oláh VJ, Rowan M, Levey AI, ... ... Rangaraju S, et al. Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain. Nature Communications. 13: 2927. PMID 35614064 DOI: 10.1038/s41467-022-30623-x  0.637
2022 Sudwarts A, Ramesha S, Gao T, Ponnusamy M, Wang S, Hansen M, Kozlova A, Bitarafan S, Kumar P, Beaulieu-Abdelahad D, Zhang X, Collier L, Szekeres C, Wood LB, Duan J, ... ... Rangaraju S, et al. BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia. Molecular Neurodegeneration. 17: 33. PMID 35526014 DOI: 10.1186/s13024-022-00535-x  0.371
2022 Raza SA, Rangaraju S. Prognostic Scores for Large Vessel Occlusion Strokes. Neurology. 97: S79-S90. PMID 34785607 DOI: 10.1212/WNL.0000000000012797  0.615
2021 Chen MJ, Ramesha S, Weinstock LD, Gao T, Ping L, Xiao H, Dammer EB, Duong DD, Levey AI, Lah JJ, Seyfried NT, Wood LB, Rangaraju S. Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease. Journal of Neuroscience Research. PMID 33729626 DOI: 10.1002/jnr.24829  0.787
2021 Ramesha S, Rayaprolu S, Bowen CA, Giver CR, Bitarafan S, Nguyen HM, Gao T, Chen MJ, Nwabueze N, Dammer EB, Engstrom AK, Xiao H, Pennati A, Seyfried NT, Katz DJ, ... ... Rangaraju S, et al. Unique molecular characteristics and microglial origin of Kv1.3 channel-positive brain myeloid cells in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33649184 DOI: 10.1073/pnas.2013545118  0.787
2020 Sarkar S, Murphy MA, Dammer EB, Olsen AL, Rangaraju S, Fraenkel E, Feany MB. Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy. Npj Parkinson's Disease. 6: 40. PMID 33311497 DOI: 10.1038/s41531-020-00143-w  0.698
2020 Rayaprolu S, Higginbotham L, Bagchi P, Watson CM, Zhang T, Levey AI, Rangaraju S, Seyfried NT. Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32898852 DOI: 10.1038/S41386-020-00840-3  0.685
2020 Ramesha S, Rayaprolu S, Rangaraju S. Flow Cytometry Approach to Characterize Phagocytic Properties of Acutely-Isolated Adult Microglia and Brain Macrophages In Vitro. Journal of Visualized Experiments : Jove. PMID 32658196 DOI: 10.3791/61467  0.32
2020 Rayaprolu S, Gao T, Xiao H, Ramesha S, Weinstock LD, Shah J, Duong DM, Dammer EB, Webster JA, Lah JJ, Wood LB, Betarbet R, Levey AI, Seyfried NT, Rangaraju S. Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease. Molecular Neurodegeneration. 15: 28. PMID 32381088 DOI: 10.1186/S13024-020-00377-5  0.781
2020 Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, ... ... Rangaraju S, et al. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature Medicine. PMID 32284590 DOI: 10.1038/S41591-020-0815-6  0.804
2020 Sarkar S, Dammer EB, Malovic E, Olsen AL, Raza SA, Gao T, Xiao H, Oliver DL, Duong D, Joers V, Seyfried N, Huang M, Kukar T, Tansey MG, Kanthasamy AG, ... Rangaraju S, et al. Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells. Frontiers in Immunology. 11: 33. PMID 32082315 DOI: 10.1096/Fasebj.2020.34.S1.00630  0.773
2019 Gao T, Jernigan J, Raza SA, Dammer EB, Xiao H, Seyfried NT, Levey AI, Rangaraju S. Transcriptional regulation of homeostatic and disease-associated-microglial genes by IRF1, LXRβ, and CEBPα. Glia. PMID 31301160 DOI: 10.1002/Glia.23678  0.758
2019 Gao T, Raza SA, Ramesha S, Nwabueze NV, Tomkins AJ, Cheng L, Xiao H, Yepes M, Rangaraju S. Temporal profiling of Kv1.3 channel expression in brain mononuclear phagocytes following ischemic stroke. Journal of Neuroinflammation. 16: 116. PMID 31153377 DOI: 10.1186/s12974-019-1510-8  0.668
2018 Ellis D, Rangaraju S, Duncan A, Hoskins M, Raza SA, Rahman H, Winningham M, Belagaje S, Bianchi N, Mohamed GA, Obideen M, Sharashidze V, Belair T, Henriquez L, Nahab F. Coagulation markers and echocardiography predict atrial fibrillation, malignancy or recurrent stroke after cryptogenic stroke. Medicine. 97: e13830. PMID 30572550 DOI: 10.1097/MD.0000000000013830  0.615
2018 Raza SA, Barreira CM, Rodrigues GM, Frankel MR, Haussen DC, Nogueira RG, Rangaraju S. Prognostic importance of CT ASPECTS and CT perfusion measures of infarction in anterior emergent large vessel occlusions. Journal of Neurointerventional Surgery. PMID 30530773 DOI: 10.1136/neurintsurg-2018-014461  0.596
2018 Rangaraju S, Dammer EB, Raza SA, Gao T, Xiao H, Betarbet R, Duong DM, Webster JA, Hales CM, Lah JJ, Levey AI, Seyfried NT. Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins. Molecular Neurodegeneration. 13: 34. PMID 29954413 DOI: 10.1186/S13024-018-0266-4  0.791
2018 Rangaraju S, Dammer EB, Raza SA, Rathakrishnan P, Xiao H, Gao T, Duong DM, Pennington MW, Lah JJ, Seyfried NT, Levey AI. Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease. Molecular Neurodegeneration. 13: 24. PMID 29784049 DOI: 10.1186/S13024-018-0254-8  0.788
2018 Raza SA, Rangaraju S. A Review of Pre-Intervention Prognostic Scores for Early Prognostication and Patient Selection in Endovascular Management of Large Vessel Occlusion Stroke. Interventional Neurology. 7: 171-181. PMID 29719555 DOI: 10.1159/000486539  0.613
2018 Rangaraju S, Raza SA, Li NX, Betarbet R, Dammer EB, Duong D, Lah JJ, Seyfried NT, Levey AI. Differential Phagocytic Properties of CD45Microglia and CD45Brain Mononuclear Phagocytes-Activation and Age-Related Effects. Frontiers in Immunology. 9: 405. PMID 29552013 DOI: 10.3389/Fimmu.2018.00405  0.789
2017 Maezawa I, Nguyen HM, Di Lucente J, Jenkins DP, Singh V, Hilt S, Kim K, Rangaraju S, Levey AI, Wulff H, Jin LW. Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer's disease: preclinical proof of concept. Brain : a Journal of Neurology. PMID 29272333 DOI: 10.1093/Brain/Awx346  0.557
2017 Raza SA, Frankel MR, Rangaraju S. Abbreviation of the Follow-Up NIH Stroke Scale Using Factor Analysis. Cerebrovascular Diseases Extra. 7: 120-129. PMID 28968607 DOI: 10.1159/000479933  0.61
2017 Rangaraju S, Raza SA, Pennati A, Deng Q, Dammer EB, Duong D, Pennington MW, Tansey MG, Lah JJ, Betarbet R, Seyfried NT, Levey AI. A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation. Journal of Neuroinflammation. 14: 128. PMID 28651603 DOI: 10.1186/S12974-017-0906-6  0.759
2015 Rangaraju S, Gearing M, Jin LW, Levey A. Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 44: 797-808. PMID 25362031 DOI: 10.3233/Jad-141704  0.552
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