John V. Moran - Publications

Affiliations: 
Human Genetics University of Michigan Medical School Ann Arbor 

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Ward JR, Khan A, Torres S, Crawford B, Nock S, Frisbie T, Moran JV, Longworth MS. Condensin I and condensin II proteins form a LINE-1 dependent super condensin complex and cooperate to repress LINE-1. Nucleic Acids Research. PMID 36169232 DOI: 10.1093/nar/gkac802  0.429
2021 Halo JV, Pendleton AL, Shen F, Doucet AJ, Derrien T, Hitte C, Kirby LE, Myers B, Sliwerska E, Emery S, Moran JV, Boyko AR, Kidd JM. Long-read assembly of a Great Dane genome highlights the contribution of GC-rich sequence and mobile elements to canine genomes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33836575 DOI: 10.1073/pnas.2016274118  0.343
2021 Zhu X, Zhou B, Pattni R, Gleason K, Tan C, Kalinowski A, Sloan S, Fiston-Lavier AS, Mariani J, Petrov D, Barres BA, Duncan L, Abyzov A, Vogel H, ... Moran JV, et al. Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia. Nature Neuroscience. PMID 33432196 DOI: 10.1038/s41593-020-00767-4  0.422
2019 Zhou W, Emery SB, Flasch DA, Wang Y, Kwan KY, Kidd JM, Moran JV, Mills RE. Identification and characterization of occult human-specific LINE-1 insertions using long-read sequencing technology. Nucleic Acids Research. PMID 31853540 DOI: 10.1093/Nar/Gkz1173  0.347
2019 Moldovan JB, Wang Y, Shuman S, Mills RE, Moran JV. RNA ligation precedes the retrotransposition of U6/LINE-1 chimeric RNA. Proceedings of the National Academy of Sciences of the United States of America. PMID 31548405 DOI: 10.1073/Pnas.1805404116  0.306
2019 Miyoshi T, Makino T, Moran JV. Poly(ADP-Ribose) Polymerase 2 Recruits Replication Protein A to Sites of LINE-1 Integration to Facilitate Retrotransposition. Molecular Cell. PMID 31473101 DOI: 10.1016/j.molcel.2019.07.018  0.505
2019 Flasch DA, Macia Á, Sánchez L, Ljungman M, Heras SR, García-Pérez JL, Wilson TE, Moran JV. Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication. Cell. PMID 30955886 DOI: 10.1016/J.Cell.2019.02.050  0.568
2018 Larson PA, Moldovan JB, Jasti N, Kidd JM, Beck CR, Moran JV. Spliced integrated retrotransposed element (SpIRE) formation in the human genome. Plos Biology. 16: e2003067. PMID 29505568 DOI: 10.1371/Journal.Pbio.2003067  0.676
2017 Ward JR, Vasu K, Deutschman E, Halawani D, Larson PA, Zhang D, Willard B, Fox PL, Moran JV, Longworth MS. Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells. Plos Genetics. 13: e1007051. PMID 29028794 DOI: 10.1371/journal.pgen.1007051  0.4
2017 Kazazian HH, Moran JV. Mobile DNA in Health and Disease. The New England Journal of Medicine. 377: 361-370. PMID 28745987 DOI: 10.1056/Nejmra1510092  0.491
2016 Kopera HC, Flasch DA, Nakamura M, Miyoshi T, Doucet AJ, Moran JV. LEAP: L1 Element Amplification Protocol. Methods in Molecular Biology (Clifton, N.J.). 1400: 339-55. PMID 26895063 DOI: 10.1007/978-1-4939-3372-3_21  0.47
2015 Richardson SR, Doucet AJ, Kopera HC, Moldovan JB, Garcia-Perez JL, Moran JV. The Influence of LINE-1 and SINE Retrotransposons on Mammalian Genomes. Microbiology Spectrum. 3: MDNA3-0061-2014. PMID 26104698 DOI: 10.1128/microbiolspec.MDNA3-0061-2014  0.396
2015 Moldovan JB, Moran JV. The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition. Plos Genetics. 11: e1005121. PMID 25951186 DOI: 10.1371/journal.pgen.1005121  0.501
2014 Singh PK, Bourque G, Craig NL, Dubnau JT, Feschotte C, Flasch DA, Gunderson KL, Malik HS, Moran JV, Peters JE, Slotkin RK, Levin HL. Mobile genetic elements and genome evolution 2014. Mobile Dna. 5: 26. PMID 30117500 DOI: 10.1186/1759-8753-5-26  0.338
2014 Richardson SR, Narvaiza I, Planegger RA, Weitzman MD, Moran JV. APOBEC3A deaminates transiently exposed single-strand DNA during LINE-1 retrotransposition. Elife. 3: e02008. PMID 24843014 DOI: 10.7554/Elife.02008  0.506
2014 Zhang A, Dong B, Doucet AJ, Moldovan JB, Moran JV, Silverman RH. RNase L restricts the mobility of engineered retrotransposons in cultured human cells. Nucleic Acids Research. 42: 3803-20. PMID 24371271 DOI: 10.1093/nar/gkt1308  0.522
2013 Macfarlane CM, Collier P, Rahbari R, Beck CR, Wagstaff JF, Igoe S, Moran JV, Badge RM. Transduction-specific ATLAS reveals a cohort of highly active L1 retrotransposons in human populations. Human Mutation. 34: 974-85. PMID 23553801 DOI: 10.1002/humu.22327  0.647
2012 Wissing S, Muñoz-Lopez M, Macia A, Yang Z, Montano M, Collins W, Garcia-Perez JL, Moran JV, Greene WC. Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility. Human Molecular Genetics. 21: 208-18. PMID 21989055 DOI: 10.1093/Hmg/Ddr455  0.582
2011 Coufal NG, Garcia-Perez JL, Peng GE, Marchetto MC, Muotri AR, Mu Y, Carson CT, Macia A, Moran JV, Gage FH. Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 20382-7. PMID 22159035 DOI: 10.1073/Pnas.1100273108  0.519
2011 Kopera HC, Moldovan JB, Morrish TA, Garcia-Perez JL, Moran JV. Similarities between long interspersed element-1 (LINE-1) reverse transcriptase and telomerase. Proceedings of the National Academy of Sciences of the United States of America. 108: 20345-50. PMID 21940498 DOI: 10.1073/pnas.1100275108  0.418
2011 Wissing S, Montano M, Garcia-Perez JL, Moran JV, Greene WC. Endogenous APOBEC3B restricts LINE-1 retrotransposition in transformed cells and human embryonic stem cells. The Journal of Biological Chemistry. 286: 36427-37. PMID 21878639 DOI: 10.1074/Jbc.M111.251058  0.395
2011 Beck CR, Garcia-Perez JL, Badge RM, Moran JV. LINE-1 elements in structural variation and disease. Annual Review of Genomics and Human Genetics. 12: 187-215. PMID 21801021 DOI: 10.1146/annurev-genom-082509-141802  0.653
2010 Doucet AJ, Hulme AE, Sahinovic E, Kulpa DA, Moldovan JB, Kopera HC, Athanikar JN, Hasnaoui M, Bucheton A, Moran JV, Gilbert N. Characterization of LINE-1 ribonucleoprotein particles. Plos Genetics. 6. PMID 20949108 DOI: 10.1371/Journal.Pgen.1001150  0.462
2010 Garcia-Perez JL, Morell M, Scheys JO, Kulpa DA, Morell S, Carter CC, Hammer GD, Collins KL, O'Shea KS, Menendez P, Moran JV. Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells. Nature. 466: 769-73. PMID 20686575 DOI: 10.1038/Nature09209  0.48
2010 Beck CR, Collier P, Macfarlane C, Malig M, Kidd JM, Eichler EE, Badge RM, Moran JV. LINE-1 retrotransposition activity in human genomes. Cell. 141: 1159-70. PMID 20602998 DOI: 10.1016/J.Cell.2010.05.021  0.713
2009 Moran JV, Malik HS. Diamonds and rust: how transposable elements influence mammalian genomes. Conference on Mobile Elements in Mammalian Genomes. Embo Reports. 10: 1306-10. PMID 19949412 DOI: 10.1038/embor.2009.248  0.374
2009 Coufal NG, Garcia-Perez JL, Peng GE, Yeo GW, Mu Y, Lovci MT, Morell M, O'Shea KS, Moran JV, Gage FH. L1 retrotransposition in human neural progenitor cells. Nature. 460: 1127-31. PMID 19657334 DOI: 10.1038/Nature08248  0.503
2008 Bennett EA, Keller H, Mills RE, Schmidt S, Moran JV, Weichenrieder O, Devine SE. Active Alu retrotransposons in the human genome. Genome Research. 18: 1875-83. PMID 18836035 DOI: 10.1101/Gr.081737.108  0.429
2007 Garcia-Perez JL, Marchetto MC, Muotri AR, Coufal NG, Gage FH, O'Shea KS, Moran JV. LINE-1 retrotransposition in human embryonic stem cells. Human Molecular Genetics. 16: 1569-77. PMID 17468180 DOI: 10.1093/Hmg/Ddm105  0.32
2007 Garcia-Perez JL, Doucet AJ, Bucheton A, Moran JV, Gilbert N. Distinct mechanisms for trans-mediated mobilization of cellular RNAs by the LINE-1 reverse transcriptase. Genome Research. 17: 602-11. PMID 17416749 DOI: 10.1101/Gr.5870107  0.42
2007 Morrish TA, Garcia-Perez JL, Stamato TD, Taccioli GE, Sekiguchi J, Moran JV. Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres. Nature. 446: 208-12. PMID 17344853 DOI: 10.1038/nature05560  0.401
2007 Hulme AE, Bogerd HP, Cullen BR, Moran JV. Selective inhibition of Alu retrotransposition by APOBEC3G. Gene. 390: 199-205. PMID 17079095 DOI: 10.1016/J.Gene.2006.08.032  0.477
2007 Gasior SL, Preston G, Hedges DJ, Gilbert N, Moran JV, Deininger PL. Characterization of pre-insertion loci of de novo L1 insertions. Gene. 390: 190-8. PMID 17067767 DOI: 10.1016/J.Gene.2006.08.024  0.567
2007 Batzer MA, Deininger PL, Jurka J, Moran JV. Introduction for the Gene special issue dedicated to the meeting "Genomic impact of eukaryotic transposable elements" at Asilomar. Gene. 390: 1-2. PMID 17027200 DOI: 10.1016/J.Gene.2006.07.036  0.305
2006 Kulpa DA, Moran JV. Cis-preferential LINE-1 reverse transcriptase activity in ribonucleoprotein particles. Nature Structural & Molecular Biology. 13: 655-60. PMID 16783376 DOI: 10.1038/nsmb1107  0.498
2006 Bogerd HP, Wiegand HL, Hulme AE, Garcia-Perez JL, O'Shea KS, Moran JV, Cullen BR. Cellular inhibitors of long interspersed element 1 and Alu retrotransposition. Proceedings of the National Academy of Sciences of the United States of America. 103: 8780-5. PMID 16728505 DOI: 10.1073/Pnas.0603313103  0.405
2006 Kubo S, Seleme MC, Soifer HS, Perez JL, Moran JV, Kazazian HH, Kasahara N. L1 retrotransposition in nondividing and primary human somatic cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 8036-41. PMID 16698926 DOI: 10.1073/Pnas.0601954103  0.63
2006 Alisch RS, Garcia-Perez JL, Muotri AR, Gage FH, Moran JV. Unconventional translation of mammalian LINE-1 retrotransposons. Genes & Development. 20: 210-24. PMID 16418485 DOI: 10.1101/gad.1380406  0.408
2005 Kulpa DA, Moran JV. Ribonucleoprotein particle formation is necessary but not sufficient for LINE-1 retrotransposition. Human Molecular Genetics. 14: 3237-48. PMID 16183655 DOI: 10.1093/hmg/ddi354  0.428
2005 Gilbert N, Lutz S, Morrish TA, Moran JV. Multiple fates of L1 retrotransposition intermediates in cultured human cells. Molecular and Cellular Biology. 25: 7780-95. PMID 16107723 DOI: 10.1128/Mcb.25.17.7780-7795.2005  0.576
2005 Muotri AR, Chu VT, Marchetto MC, Deng W, Moran JV, Gage FH. Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition. Nature. 435: 903-10. PMID 15959507 DOI: 10.1038/Nature03663  0.322
2003 Deininger PL, Moran JV, Batzer MA, Kazazian HH. Mobile elements and mammalian genome evolution. Current Opinion in Genetics & Development. 13: 651-8. PMID 14638329 DOI: 10.1016/J.Gde.2003.10.013  0.552
2003 Lutz SM, Vincent BJ, Kazazian HH, Batzer MA, Moran JV. Allelic heterogeneity in LINE-1 retrotransposition activity. American Journal of Human Genetics. 73: 1431-7. PMID 14610717 DOI: 10.1086/379744  0.663
2003 Brouha B, Schustak J, Badge RM, Lutz-Prigge S, Farley AH, Moran JV, Kazazian HH. Hot L1s account for the bulk of retrotransposition in the human population. Proceedings of the National Academy of Sciences of the United States of America. 100: 5280-5. PMID 12682288 DOI: 10.1073/Pnas.0831042100  0.706
2003 Badge RM, Alisch RS, Moran JV. ATLAS: a system to selectively identify human-specific L1 insertions. American Journal of Human Genetics. 72: 823-38. PMID 12632328 DOI: 10.1086/373939  0.608
2002 Gilbert N, Lutz-Prigge S, Moran JV. Genomic deletions created upon LINE-1 retrotransposition. Cell. 110: 315-25. PMID 12176319 DOI: 10.1016/S0092-8674(02)00828-0  0.583
2002 Myers JS, Vincent BJ, Udall H, Watkins WS, Morrish TA, Kilroy GE, Swergold GD, Henke J, Henke L, Moran JV, Jorde LB, Batzer MA. A comprehensive analysis of recently integrated human Ta L1 elements. American Journal of Human Genetics. 71: 312-26. PMID 12070800 DOI: 10.1086/341718  0.587
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