Year |
Citation |
Score |
2024 |
Varela Martins T, Silva de Melo BM, Toller-Kawahisa JE, Silva GV, Anibal-Silva CE, Paiva IM, Publio GA, Rosa MH, da Silva Souza C, Zamboni DS, Cunha FQ, Cunha TM, Ryffel B, Riteau N, Alves-Filho JC. The DNA sensor AIM2 mediates psoriasiform inflammation by inducing type 3 immunity. Jci Insight. PMID 39352743 DOI: 10.1172/jci.insight.171894 |
0.489 |
|
2024 |
Silva RL, Lopes AH, Becerra A, Fonseca MM, Manganin A, Saraiva ALL, Cunha FQ, Alves-Filho JC, Zamboni DS, Cunha TM. Molecular mechanisms of zymosan-induced inflammasome activation in macrophages. Cellular Signalling. 111418. PMID 39304096 DOI: 10.1016/j.cellsig.2024.111418 |
0.771 |
|
2024 |
Lee SH, Bonifacio F, Prudente AS, Choi Y, Roh J, Adjafre BL, Park CK, Jung SJ, Cunha TM, Berta T. STING recognition of viral dsDNA by nociceptors mediates pain in mice. Brain, Behavior, and Immunity. PMID 39025416 DOI: 10.1016/j.bbi.2024.07.013 |
0.803 |
|
2024 |
Brum ES, Fialho MFP, Souza Monteiro de Araújo D, Landini L, Marini M, Titiz M, Kuhn BL, Frizzo CP, Araújo PHS, Guimarães RM, Cunha TM, Silva CR, Trevisan G, Geppetti P, Nassini R, et al. Schwann cell TRPA1 elicits reserpine-induced fibromyalgia pain in mice. British Journal of Pharmacology. PMID 38772415 DOI: 10.1111/bph.16413 |
0.737 |
|
2024 |
Lessa TLADS, Correia TML, Santos TCD, da Silva RP, Silva BPD, Cavallini MCM, Rocha LS, Souza Peixoto A, Cugnasca BS, Cervi G, Correra TC, Gonçalves AC, Festuccia WTL, Cunha TM, Yatsuda R, et al. A novel diselenide attenuates the carrageenan-induced inflammation by reducing neutrophil infiltration and the resulting tissue damage in mice. Free Radical Research. 1-20. PMID 38588405 DOI: 10.1080/10715762.2024.2336566 |
0.317 |
|
2023 |
Dos Ramos Almeida CJL, Veras FP, Paiva IM, Schneider AH, Silva JDC, Gomes GF, Costa VF, Silva BMS, Caetite DB, Silva CMS, Salina ACG, Martins R, Bonilha CS, Cunha LD, Jamur MC, ... ... Cunha TM, et al. Neutrophil virucidal activity against SARS-CoV-2 is mediated by NETs. The Journal of Infectious Diseases. PMID 38015657 DOI: 10.1093/infdis/jiad526 |
0.416 |
|
2023 |
Colón DF, Wanderley CW, Turato WM, Borges VF, Franchin M, Castanheira FVS, Nascimento D, Prado D, Haruo Fernandes de Lima M, Volpon LC, Kavaguti SK, Carlotti AP, Carmona F, Franklin BS, Cunha TM, et al. Pediatric sepsis survivors are resistant to sepsis-induced long-term immune dysfunction. British Journal of Pharmacology. PMID 37990806 DOI: 10.1111/bph.16286 |
0.41 |
|
2023 |
Córneo ES, Veras FP, Gomes GF, Schneider AH, Manuella B, Almeida CJLR, Silva CM, Martins RB, Batah SS, Simon CS, Prestes GDS, Alves-Filho JC, Arruda E, Louzada-Junior P, de Oliveira RDR, ... ... Cunha TM, et al. Enoxaparin improves COVID-19 by reducing Neutrophils Extracellular Traps (NETs) production. Clinical Immunology (Orlando, Fla.). 257: 109836. PMID 37951516 DOI: 10.1016/j.clim.2023.109836 |
0.449 |
|
2023 |
Damasceno LEA, Cunha TM, Cunha FQ, Sparwasser T, Alves-Filho JC. A clinically-relevant STING agonist restrains human T17 cell inflammatory profile. International Immunopharmacology. 124: 111007. PMID 37778170 DOI: 10.1016/j.intimp.2023.111007 |
0.418 |
|
2023 |
Schneider AH, Taira TM, Públio GA, da Silva Prado D, Yabuta PBD, Dos Santos JC, Machado CC, de Souza FFL, Venturini LGR, de Oliveira RDR, Cunha TM, Alves-Filho JC, Louzada-Júnior P, da Silva TA, Fukada SY, et al. Neutrophil extracellular traps mediate bone erosion in rheumatoid arthritis by enhancing RANKL-induced osteoclastogenesis. British Journal of Pharmacology. PMID 37625900 DOI: 10.1111/bph.16227 |
0.415 |
|
2023 |
de Lima MHF, Machado CC, Nascimento DC, Silva CMS, Toller-Kawahisa JE, Rodrigues TS, Veras FP, Pontelli MC, Castro IA, Zamboni DS, Filho JA, Cunha TM, Arruda E, da Cunha LD, Oliveira RDR, et al. The TIGIT T regulatory cells subset associates with nosocomial infection and fatal outcome in COVID-19 patients under mechanical ventilation. Scientific Reports. 13: 13599. PMID 37604833 DOI: 10.1038/s41598-023-39924-7 |
0.4 |
|
2023 |
Toller-Kawahisa JE, Hiroki CH, Silva CMS, Nascimento DC, Públio GA, Martins TV, Damasceno LEA, Veras FP, Viacava PR, Sukesada FY, Day EA, Zotta A, Ryan TAJ, Moreira da Silva R, Cunha TM, et al. The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils. Nature Communications. 14: 4280. PMID 37460614 DOI: 10.1038/s41467-023-40021-6 |
0.399 |
|
2023 |
Guimarães RM, Aníbal-Silva CE, Davoli-Ferreira M, Gomes FIF, Mendes AS, Cavallini MCM, Fonseca MM, Damasceno S, Andrade LP, Colonna M, Rivat C, Cunha FQ, Alves-Filho JC, Cunha TM. Neuron-associated macrophage proliferation in the sensory ganglia is associated with peripheral nerve injury-induced neuropathic pain involving CX3CR1 signaling. Elife. 12. PMID 37254842 DOI: 10.7554/eLife.78515 |
0.809 |
|
2023 |
Barreto EA, Cruz AS, Veras FP, Martins R, Bernardelli RS, Paiva IM, Lima TM, Singh Y, Guimarães RC, Damasceno S, Pereira N, Alves JM, Gonçalves TT, Forato J, Muraro SP, ... ... Cunha TM, et al. COVID-19-related hyperglycemia is associated with infection of hepatocytes and stimulation of gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217119120. PMID 37186819 DOI: 10.1073/pnas.2217119120 |
0.351 |
|
2023 |
Silva BM, Gomes GF, Veras FP, Cambier S, Silva GV, Quadros AU, Caetité DB, Nascimento DC, Silva CM, Costa Silva JC, Damasceno S, Schneider AH, Beretta F, Batah SS, Castro IM, ... ... Cunha TM, et al. C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps. The Journal of Clinical Investigation. PMID 37104043 DOI: 10.1172/JCI163105 |
0.411 |
|
2023 |
de Melo BMS, Veras FP, Zwicky P, Lima D, Ingelfinger F, Varela T, da Silva Prado D, Schärli S, Publio G, Hiroki CH, Melo PH, Saraiva A, Norbiato T, Lima L, Ryffel B, ... ... Cunha TM, et al. S100A9 drives the chronification of psoriasiform inflammation by inducing IL-23/type 3 immunity. The Journal of Investigative Dermatology. PMID 36921684 DOI: 10.1016/j.jid.2023.02.026 |
0.48 |
|
2023 |
Veras FP, Gomes GF, Silva BMS, Caetité DB, Almeida CJLR, Silva CMS, Schneider AH, Corneo ES, Bonilha CS, Batah SS, Martins R, Arruda E, Fabro AT, Alves-Filho JC, Cunha TM, et al. Targeting neutrophils extracellular traps (NETs) reduces multiple organ injury in a COVID-19 mouse model. Respiratory Research. 24: 66. PMID 36864506 DOI: 10.1186/s12931-023-02336-2 |
0.374 |
|
2023 |
Rodrigues TS, Caetano CCS, de Sá KSG, Almeida L, Becerra A, Gonçalves AV, de Sousa Lopes L, Oliveira S, Mascarenhas DPA, Batah SS, Silva BM, Gomes GF, Castro R, Martins RB, Avila J, ... ... Cunha TM, et al. CASP4/11 contributes to NLRP3 activation and COVID-19 exacerbation. The Journal of Infectious Diseases. PMID 36763010 DOI: 10.1093/infdis/jiad037 |
0.48 |
|
2023 |
Borghi SM, Zaninelli TH, Saraiva-Santos T, Bertozzi MM, Cardoso RDR, Carvalho TT, Ferraz CR, Camilios-Neto D, Cunha FQ, Cunha TM, Pinho-Ribeiro FA, Casagrande R, Verri WA. Brief research report: Repurposing pentoxifylline to treat intense acute swimming-Induced delayed-onset muscle soreness in mice: Targeting peripheral and spinal cord nociceptive mechanisms. Frontiers in Pharmacology. 13: 950314. PMID 36703752 DOI: 10.3389/fphar.2022.950314 |
0.612 |
|
2023 |
Oliveira I, Costa V, Veras F, Ferreira I, Cunha F, Cunha T, Monteiro W, Arantes E, Pucca M. A Promising Biomolecule Able to Degrade Neutrophil Extracellular Traps: PDE, a Rattlesnake Phosphodiesterase. Toxins. 15. PMID 36668864 DOI: 10.3390/toxins15010044 |
0.41 |
|
2022 |
Veras FP, Publio GA, Melo BM, Prado DS, Norbiato T, Cecilio NT, Hiroki C, Damasceno LEA, Jung R, Toller-Kawahisa JE, Martins TV, Assunção SF, Lima D, Alves MG, Vieira GV, ... ... Cunha TM, et al. Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation. Cell Reports. 41: 111897. PMID 36577385 DOI: 10.1016/j.celrep.2022.111897 |
0.509 |
|
2022 |
Borges VF, Galant LS, Kanashiro A, Castanheira FVES, Monteiro VVS, Duarte DÂ, Rodrigues FC, Silva CMS, Schneider AH, Cebinelli GCM, de Lima MHF, Viola JPB, Cunha TM, da Costa Neto CM, Alves-Filho JCF, et al. FK506 impairs neutrophil migration that results in increased polymicrobial sepsis susceptibility. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 36401631 DOI: 10.1007/s00011-022-01669-w |
0.496 |
|
2022 |
Franchin M, Taira TM, da Silva Prado D, Hernandez CAS, de Andrade FB, Abdalla HB, Napimoga MH, Cunha TM, Fukada SY, Rosalen PL. PI3Kγ controls IL-17A expression and attenuates alveolar bone loss in an experimental periodontitis model. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 36333479 DOI: 10.1007/s00011-022-01662-3 |
0.774 |
|
2022 |
Maganin AG, Souza GR, Fonseca MD, Lopes AH, Mano Guimarães RM, Dagostin A, Cecilio NT, Mendes AS, Gonçalves WA, Silva CE, Fernandes Gomes FI, Mauriz Marques LM, Silva RL, Arruda LM, Santana DA, ... ... Cunha T, et al. Meningeal dendritic cells drive neuropathic pain through elevation of the kynurenine metabolic pathway in mice. The Journal of Clinical Investigation. PMID 36227694 DOI: 10.1172/JCI153805 |
0.783 |
|
2022 |
Vieira TN, Saraiva ALL, Guimarães RM, Luiz JPM, Pinto LG, de Melo Rodrigues Ávila V, Goulart LR, Cunha-Junior JP, McNaughton PA, Cunha TM, Ferreira J, Silva CR. Angiotensin type 2 receptor antagonism as a new target to manage gout. Inflammopharmacology. PMID 36173505 DOI: 10.1007/s10787-022-01076-x |
0.726 |
|
2022 |
Bertozzi MM, Saraiva-Santos T, Zaninelli TH, Pinho-Ribeiro FA, Fattori V, Staurengo-Ferrari L, Ferraz CR, Domiciano TP, Calixto-Campos C, Borghi SM, Zarpelon AC, Cunha TM, Casagrande R, Verri WA. Ehrlich Tumor Induces TRPV1-Dependent Evoked and Non-Evoked Pain-like Behavior in Mice. Brain Sciences. 12. PMID 36138983 DOI: 10.3390/brainsci12091247 |
0.585 |
|
2022 |
de Almeida L, da Silva ALN, Rodrigues TS, Oliveira S, Ishimoto AY, Seribelli AA, Becerra A, Andrade WA, Ataide MA, Caetano CCS, de Sá KSG, Pelisson N, Martins RB, de Paula Souza J, Arruda E, ... ... Cunha TM, et al. Identification of immunomodulatory drugs that inhibit multiple inflammasomes and impair SARS-CoV-2 infection. Science Advances. 8: eabo5400. PMID 36103544 DOI: 10.1126/sciadv.abo5400 |
0.493 |
|
2022 |
Puhl AC, Gomes GF, Damasceno S, Fritch EJ, Levi JA, Johnson NJ, Scholle F, Premkumar L, Hurst BL, Lee-Montiel F, Veras FP, Batah SS, Fabro AT, Moorman NJ, Yount BL, ... ... Cunha TM, et al. Vandetanib Blocks the Cytokine Storm in SARS-CoV-2-Infected Mice. Acs Omega. 7: 31935-31944. PMID 36097511 DOI: 10.1021/acsomega.2c02794 |
0.535 |
|
2022 |
Wanderley CWS, Maganin A, Adjafre B, Mendes AS, Anibal Silva CE, Quadros AU, Luiz JPM, Silva CMS, Silva NR, Oliveira FF, Gomes FIF, Restrepo JLJ, Speck-Hernandez CA, Turaça F, Silva GVL, ... ... Cunha TM, et al. PD-1/PD-L1 inhibition enhances chemotherapy-induced neuropathic pain by suppressing neuroimmune antinociceptive signaling. Cancer Immunology Research. PMID 36083496 DOI: 10.1158/2326-6066.CIR-22-0003 |
0.77 |
|
2022 |
Crunfli F, Carregari VC, Veras FP, Silva LS, Nogueira MH, Antunes ASLM, Vendramini PH, Valença AGF, Brandão-Teles C, Zuccoli GDS, Reis-de-Oliveira G, Silva-Costa LC, Saia-Cereda VM, Smith BJ, Codo AC, ... ... Cunha TM, et al. Morphological, cellular, and molecular basis of brain infection in COVID-19 patients. Proceedings of the National Academy of Sciences of the United States of America. 119: e2200960119. PMID 35951647 DOI: 10.1073/pnas.2200960119 |
0.738 |
|
2022 |
Silva CMS, Wanderley CWS, Veras FP, Gonçalves AV, Lima MHF, Toller-Kawahisa JE, Gomes GF, Nascimento DC, Monteiro VVS, Paiva IM, Almeida CJLR, Caetité DB, Silva JC, Lopes MIF, Bonjorno LP, ... ... Cunha TM, et al. Gasdermin-D activation by SARS-CoV-2 triggers NET and mediate COVID-19 immunopathology. Critical Care (London, England). 26: 206. PMID 35799268 DOI: 10.1186/s13054-022-04062-5 |
0.473 |
|
2022 |
Franchin M, Luiz Rosalen P, da Silva Prado D, César Paraluppi M, Leal Silva R, Damasceno LEA, Morelo DFC, Napimoga MH, Cunha FQ, Alves-Filho JC, Cunha TM. Cinnamoyloxy-mammeisin, a coumarin from propolis of stingless bees, attenuates Th17 cell differentiation and autoimmune inflammation via STAT3 inhibition. European Journal of Pharmacology. 929: 175127. PMID 35787889 DOI: 10.1016/j.ejphar.2022.175127 |
0.555 |
|
2022 |
Salina ACG, Dos Santos D, Rodrigues TS, Fortes-Rocha M, Freitas-Filho EG, Alzamora-Terrel DL, Castro IMS, Fraga-Silva TF, de Lima MHF, Nascimento DC, Silva CM, Toller-Kawahisa JE, Becerra A, Oliveira S, Caetite DB, ... ... Cunha TM, et al. Efferocytosis of SARS-CoV-2-infected dying cells impairs macrophage anti-inflammatory functions and clearance of apoptotic cells. Elife. 11. PMID 35666101 DOI: 10.7554/eLife.74443 |
0.549 |
|
2022 |
Brandolini L, d'Angelo M, Novelli R, Castelli V, Giorgio C, Sirico A, Cocchiaro P, D'Egidio F, Benedetti E, Cristiano C, Bugatti A, Ruocco A, Amendola PG, Talarico C, Manelfi C, ... ... Cunha TM, et al. Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions. Cell Death & Disease. 13: 500. PMID 35614037 DOI: 10.1038/s41419-022-04964-w |
0.323 |
|
2022 |
Damasceno LEA, Cebinelli GCM, Fernandes MF, Nascimento DC, Públio GA, Vinolo MAR, Oliveira SC, Sparwasser T, Cunha TM, Cunha FQ, Alves-Filho JC. STING is an intrinsic checkpoint inhibitor that restrains the T17 cell pathogenic program. Cell Reports. 39: 110838. PMID 35613599 DOI: 10.1016/j.celrep.2022.110838 |
0.443 |
|
2022 |
Puhl AC, Gomes GF, Damasceno S, Godoy AS, Noske GD, Nakamura AM, Gawriljuk VO, Fernandes RS, Monakhova N, Riabova O, Lane TR, Makarov V, Veras FP, Batah SS, Fabro AT, ... ... Cunha TM, et al. Pyronaridine Protects against SARS-CoV-2 Infection in Mouse. Acs Infectious Diseases. PMID 35609344 DOI: 10.1021/acsinfecdis.2c00091 |
0.437 |
|
2022 |
Pontelli MC, Castro IA, Martins RB, La Serra L, Veras FP, Nascimento DC, Silva CM, Cardoso RS, Rosales R, Gomes R, Lima TM, Souza JP, Vitti BC, Caetité DB, de Lima MHF, ... ... Cunha TM, et al. SARS-CoV-2 productively infects primary human immune system cells in vitro and in COVID-19 patients. Journal of Molecular Cell Biology. PMID 35451490 DOI: 10.1093/jmcb/mjac021 |
0.391 |
|
2022 |
Castro PATS, Machanocker DH, Luna GF, Barbosa GM, Cunha JE, Cunha TM, Cunha FQ, Russo TL, Salvini TF. Clinical-Like Cryotherapy in Acute Knee Arthritis Protects Neuromuscular Junctions of Quadriceps and Reduces Joint Inflammation in Mice. Biomed Research International. 2022: 7442289. PMID 35103239 DOI: 10.1155/2022/7442289 |
0.424 |
|
2022 |
Batah SS, Benatti MN, Siyuan L, Telini WM, Barboza JO, Menezes MB, Nadai TR, Sá KSG, Vaswani CM, Gupta S, Zamboni DS, Wada DT, Calado RT, Oliveira RDR, Louzada-Junior P, ... ... Cunha TM, et al. COVID-19 bimodal clinical and pathological phenotypes. Clinical and Translational Medicine. 12: e648. PMID 35075808 DOI: 10.1002/ctm2.648 |
0.304 |
|
2022 |
Borghi SM, Bussulo SKD, Pinho-Ribeiro FA, Fattori V, Carvalho TT, Rasquel-Oliveira FS, Zaninelli TH, Ferraz CR, Casella AMB, Cunha FQ, Cunha TM, Casagrande R, Verri WA. Intense Acute Swimming Induces Delayed-Onset Muscle Soreness Dependent on Spinal Cord Neuroinflammation. Frontiers in Pharmacology. 12: 734091. PMID 35069187 DOI: 10.3389/fphar.2021.734091 |
0.627 |
|
2022 |
Castro PATS, Barbosa GM, Machanocker DH, Peres RS, Cunha TM, Cunha JE, Oliveira FFB, Ramalho FS, Russo TL, Cunha FQ, Salvini TF. Clinical-like cryotherapy in acute knee arthritis of the knee improves inflammation signs, pain, joint swelling, and motor performance in mice. Plos One. 17: e0261667. PMID 35061737 DOI: 10.1371/journal.pone.0261667 |
0.469 |
|
2022 |
Raymondi Silva J, Iftinca M, Fernandes Gomes FI, Segal JP, Smith OMA, Bannerman CA, Silva Mendes A, Defaye M, Robinson MEC, Gilron I, Cunha TM, Altier C, Ghasemlou N. Skin-resident dendritic cells mediate postoperative pain via CCR4 on sensory neurons. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35046040 DOI: 10.1073/pnas.2118238119 |
0.306 |
|
2021 |
Puhl AC, Gomes GF, Damasceno S, Fritch EJ, Levi JA, Johnson NJ, Scholle F, Premkumar L, Hurst BL, LeeMontiel F, Veras FP, Batah SS, Fabro AT, Moorman NJ, Yount BL, ... ... Cunha TM, et al. Vandetanib Reduces Inflammatory Cytokines and Ameliorates COVID-19 in Infected Mice. Biorxiv : the Preprint Server For Biology. PMID 34981062 DOI: 10.1101/2021.12.16.472155 |
0.462 |
|
2021 |
Ventura Fernandes BH, Feitosa NM, Barbosa AP, Bomfim CG, Garnique AMB, Rosa IF, Rodrigues MS, Doretto LB, Costa DF, Santos BC, Franco GA, Neto JF, Lunardi JS, Bellot MS, Alves NPC, ... ... Cunha TM, et al. Toxicity of spike fragments SARS-CoV-2 S protein for zebrafish: A tool to study its hazardous for human health? The Science of the Total Environment. 152345. PMID 34942250 DOI: 10.1016/j.scitotenv.2021.152345 |
0.356 |
|
2021 |
Silva NR, Gomes FIF, Lopes AHP, Cortez IL, Dos Santos JC, Silva CEA, Mechoulam R, Gomes FV, Cunha TM, Guimarães FS. The Cannabidiol Analog PECS-101 Prevents Chemotherapy-Induced Neuropathic Pain via PPARγ Receptors. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 19: 434-449. PMID 34904193 DOI: 10.1007/s13311-021-01164-w |
0.361 |
|
2021 |
Silva NR, Gomes FIF, Lopes AHP, Cortez IL, Dos Santos JC, Silva CEA, Mechoulam R, Gomes FV, Cunha TM, Guimarães FS. The Cannabidiol Analog PECS-101 Prevents Chemotherapy-Induced Neuropathic Pain via PPARγ Receptors. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 19: 434-449. PMID 34904193 DOI: 10.1007/s13311-021-01164-w |
0.361 |
|
2021 |
Almeida GM, Souza JP, Mendes ND, Pontelli MC, Pinheiro NR, Nogueira GO, Cardoso RS, Paiva IM, Ferrari GD, Veras FP, Cunha FQ, Horta-Junior JAC, Alberici LC, Cunha TM, Podolsky-Gondim GG, et al. Neural Infection by Oropouche Virus in Adult Human Brain Slices Induces an Inflammatory and Toxic Response. Frontiers in Neuroscience. 15: 674576. PMID 34887719 DOI: 10.3389/fnins.2021.674576 |
0.385 |
|
2021 |
Saraiva AL, Peres RS, Veras FP, Talbot J, de Lima KA, Luiz JPM, Cunha TM, Louzada-Junior P, Cunha FQ, Alves-Filho JC. Citrullinated human fibrinogen triggers arthritis through an inflammatory response mediated by IL-23/IL-17 immune axis. International Immunopharmacology. 101: 108363. PMID 34810129 DOI: 10.1016/j.intimp.2021.108363 |
0.51 |
|
2021 |
Nascimento DC, Viacava PR, Ferreira RG, Damaceno MA, Piñeros AR, Melo PH, Donate PB, Toller-Kawahisa JE, Zoppi D, Veras FP, Peres RS, Menezes-Silva L, Caetité D, Oliveira AER, Castro ÍMS, ... ... Cunha TM, et al. Sepsis expands a CD39 plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity. Immunity. PMID 34473957 DOI: 10.1016/j.immuni.2021.08.005 |
0.417 |
|
2021 |
Silva CM, Wanderley CWS, Veras FP, Sonego F, Nascimento DC, Gonçalves AV, Martins TV, Colón DF, Borges VF, Brauer VS, Damasceno LEA, Silva KP, Toller-Kawahisa JE, Batah SS, Souza ALJ, ... ... Cunha TM, et al. Gasdermin D inhibition prevents multiple organ dysfunction during sepsis by blocking NET formation. Blood. PMID 34407544 DOI: 10.1182/blood.2021011525 |
0.41 |
|
2021 |
de Lima MHF, Hiroki CH, de Fátima Borges V, Cebinelli GCM, Santos J, Rosa MH, Silva CMS, Wanderley CWS, Gonçalves AV, Silva Quirino GF, Zamboni DS, Cunha TM, Filho JA, Cunha FQ. Sepsis-induced immunosuppression is marked by an expansion of a highly suppressive repertoire of FOXP3 +T regulatory cells-expressing TIGIT. The Journal of Infectious Diseases. PMID 34379757 DOI: 10.1093/infdis/jiab405 |
0.359 |
|
2021 |
Trevelin SC, Sag CM, Zhang M, Alves-Filho JC, Cunha TM, Santos CXD, Sawyer G, Murray T, Brewer A, Laurindo FRM, Protti A, Lopes LR, Ivetic A, Cunha FQ, Shah AM. Endothelial Nox2 Limits Systemic Inflammation and Hypotension in Endotoxemia by Controlling Expression of Toll-Like Receptor 4. Shock (Augusta, Ga.). 56: 268-277. PMID 34276040 DOI: 10.1097/SHK.0000000000001706 |
0.465 |
|
2021 |
Silva CEA, Guimarães RM, Cunha TM. Sensory neuron-associated macrophages as novel modulators of neuropathic pain. Pain Reports. 6: e873. PMID 33981924 DOI: 10.1097/PR9.0000000000000873 |
0.777 |
|
2021 |
Abdalla HB, Napimoga MH, de Macedo Maganin AG, Lopes AH, Cunha TM, Gill HS, Clemente-Napimoga JT. The role of adenosine A receptor in the peripheral tramadol's effect in the temporomandibular joint of rats. International Immunopharmacology. 97: 107680. PMID 33932698 DOI: 10.1016/j.intimp.2021.107680 |
0.814 |
|
2021 |
Ferraz CR, Carvalho TT, Fattori V, Saraiva-Santos T, Pinho-Ribeiro FA, Borghi SM, Manchope MF, Zaninelli TH, Cunha TM, Casagrande R, Clissa PB, Verri WA. Jararhagin, a snake venom metalloproteinase, induces mechanical hyperalgesia in mice with the neuroinflammatory contribution of spinal cord microglia and astrocytes. International Journal of Biological Macromolecules. PMID 33662422 DOI: 10.1016/j.ijbiomac.2021.02.178 |
0.584 |
|
2021 |
Lopes MI, Bonjorno LP, Giannini MC, Amaral NB, Menezes PI, Dib SM, Gigante SL, Benatti MN, Rezek UC, Emrich-Filho LL, Sousa BAA, Almeida SCL, Luppino Assad R, Veras FP, Schneider A, ... ... Cunha TM, et al. Beneficial effects of colchicine for moderate to severe COVID-19: a randomised, double-blinded, placebo-controlled clinical trial. Rmd Open. 7. PMID 33542047 DOI: 10.1136/rmdopen-2020-001455 |
0.317 |
|
2021 |
Donate PB, Alves de Lima K, Peres RS, Almeida F, Fukada SY, Silva TA, Nascimento DC, Cecilio NT, Talbot J, Oliveira RD, Passos GA, Alves-Filho JC, Cunha TM, Louzada-Junior P, Liew FY, et al. Cigarette smoke induces in Th17 cells that enhance osteoclastogenesis in inflammatory arthritis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33443169 DOI: 10.1073/pnas.2017120118 |
0.426 |
|
2021 |
Rodrigues TS, de Sá KSG, Ishimoto AY, Becerra A, Oliveira S, Almeida L, Gonçalves AV, Perucello DB, Andrade WA, Castro R, Veras FP, Toller-Kawahisa JE, Nascimento DC, de Lima MHF, Silva CMS, ... ... Cunha TM, et al. Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients. The Journal of Experimental Medicine. 218. PMID 33231615 DOI: 10.1084/jem.20201707 |
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Pontelli MC, Castro IA, Martins RB, Veras FP, Serra L, Nascimento DC, Cardoso RS, Rosales R, Lima TM, Souza JP, Caetité DB, de Lima MHF, Kawahisa JT, Giannini MC, Bonjorno LP, ... ... Cunha TM, et al. Infection of human lymphomononuclear cells by SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 34013264 DOI: 10.1101/2020.07.28.225912 |
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Borghi SM, Fattori V, Carvalho TT, Tatakihara VLH, Zaninelli TH, Pinho-Ribeiro FA, Ferraz CR, Staurengo-Ferrari L, Casagrande R, Pavanelli WR, Cunha FQ, Cunha TM, Pinge-Filho P, Verri WA. Experimental Infection Induces Pain in Mice Dependent on Early Spinal Cord Glial Cells and NFκB Activation and Cytokine Production. Frontiers in Immunology. 11: 539086. PMID 33574810 DOI: 10.3389/fimmu.2020.539086 |
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2020 |
Schneider AH, Machado CC, Veras FP, Maganin AGM, de Souza FFL, Barroso LC, de Oliveira RDR, Alves-Filho JC, Cunha TM, Fukada SY, Louzada-Júnior P, da Silva TA, Cunha FQ. Neutrophil extracellular traps mediate joint hyperalgesia induced by immune inflammation. Rheumatology (Oxford, England). PMID 33367912 DOI: 10.1093/rheumatology/keaa794 |
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Correa LB, Seito LN, Manchope MF, Verri WA, Cunha TM, Henriques MG, Rosas EC. Methyl gallate attenuates inflammation induced by Toll-like receptor ligands by inhibiting MAPK and NF-Κb signaling pathways. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 33037469 DOI: 10.1007/s00011-020-01407-0 |
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Machado VF, Parra RS, Leite CA, Minto SB, Cunha TM, Cunha FQ, Garcia SB, Feitosa MR, da Rocha JJR, Feres O. Experimental Model of Rectal Carcinogenesis Induced by N-Methyl-N-Nitrosoguanidine in Mice with Endoscopic Evaluation. International Journal of Medical Sciences. 17: 2505-2510. PMID 33029093 DOI: 10.7150/ijms.48231 |
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2020 |
Cebinelli GCM, de Lima KA, Silva Castanheira FVE, Hiroki CH, Monteiro VVS, de Lima MHF, Nascimento DCB, Alves Filho JC, Cunha TM, Cunha FQ. CCR2-deficient mice are protected to sepsis by the disruption of the inflammatory monocytes emigration from the bone marrow. Journal of Leukocyte Biology. PMID 33020963 DOI: 10.1002/JLB.4MR0820-049RR |
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Cecílio NT, Souza GR, Alves-Filho JC, Cunha FQ, Cunha TM. 9The PI3Kγ/AKT signaling pathway mediates peripheral antinociceptive action of dipyrone. Fundamental & Clinical Pharmacology. PMID 32979233 DOI: 10.1111/fcp.12606 |
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2020 |
Zanata GC, Pinto LG, da Silva NR, Lopes AHP, de Oliveira FFB, Schivo IRS, Cunha FQ, McNaughton P, Cunha TM, Silva RL. Blockade of Bradykinin Receptors or Angiotensin II Type 2 Receptor Prevents Paclitaxel-Associated Acute Pain Syndrome in Mice. European Journal of Pain (London, England). PMID 32965065 DOI: 10.1002/ejp.1660 |
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2020 |
Veras FP, Pontelli MC, Silva CM, Toller-Kawahisa JE, de Lima M, Nascimento DC, Schneider AH, Caetité D, Tavares LA, Paiva IM, Rosales R, Colón D, Martins R, Castro IA, Almeida GM, ... ... Cunha TM, et al. SARS-CoV-2-triggered neutrophil extracellular traps mediate COVID-19 pathology. The Journal of Experimental Medicine. 217. PMID 32926098 DOI: 10.1084/Jem.20201129 |
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2020 |
Lopes AH, Silva RL, Fonseca MD, Gomes FI, Maganin AG, Ribeiro LS, Marques LMM, Cunha FQ, Alves-Filho JC, Zamboni DS, Lopes NP, Franklin BS, Gombault A, Ramalho FS, Quesniaux VFJ, ... ... Cunha TM, et al. Molecular basis of carrageenan-induced cytokines production in macrophages. Cell Communication and Signaling : Ccs. 18: 141. PMID 32894139 DOI: 10.1186/S12964-020-00621-X |
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Fattori V, Staurengo-Ferrari L, Zaninelli TH, Casagrande R, Oliveira RD, Louzada-Junior P, Cunha TM, Alves-Filho JC, Teixeira MM, Cunha FQ, Amaral FA, Verri WA. IL-33 enhances macrophage release of IL-1β and promotes pain and inflammation in gouty arthritis. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 32886146 DOI: 10.1007/S00011-020-01399-X |
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Luiz JPM, Toller-Kawahisa JE, Viacava PR, Nascimento DC, Pereira PT, Saraiva AL, Prado DS, LeBert M, Giurisato E, Tournier C, Cunha TM, Cunha FQ, Quesniaux V, Ryffel B, Alves-Filho JC. MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression. Journal of Leukocyte Biology. PMID 32745297 DOI: 10.1002/Jlb.1Ma0520-016R |
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2020 |
Davoli-Ferreira M, de Lima KA, Fonseca MM, Guimarães RM, Gomes FI, Cavallini MC, Quadros AU, Kusuda R, Cunha FQ, Alves-Filho JC, Cunha TM. Regulatory T cells counteract neuropathic pain through inhibition of the Th1 response at the site of peripheral nerve injury. Pain. 161: 1730-1743. PMID 32701834 DOI: 10.1097/J.Pain.0000000000001879 |
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2020 |
Damasceno LEA, Prado DS, Veras FP, Fonseca MM, Toller-Kawahisa JE, Rosa MH, Públio GA, Martins TV, Ramalho FS, Waisman A, Cunha FQ, Cunha TM, Alves-Filho JC. PKM2 promotes Th17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation. The Journal of Experimental Medicine. 217. PMID 32697823 DOI: 10.1084/Jem.20190613 |
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2020 |
Prado DS, Veras FP, Ferreira RG, Damasceno LEA, Melo PH, Zamboni DS, Cunha TM, Cunha FQ, Alves-Filho JC. NLRP12 controls arthritis severity by acting as a checkpoint inhibitor of Th17 cell differentiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32632939 DOI: 10.1096/Fj.202000795R |
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2020 |
Abdalla HB, Napimoga MH, Lopes AH, de Macedo Maganin AG, Cunha TM, Van Dyke TE, Clemente Napimoga JT. Activation of PPAR-γ induces macrophage polarization and reduces neutrophil migration mediated by heme oxygenase 1. International Immunopharmacology. 84: 106565. PMID 32388213 DOI: 10.1016/j.intimp.2020.106565 |
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Silva CR, Melo BMS, Silva JR, Lopes AH, Pereira JA, Cecilio NT, Berlink J, Souza GG, Lucas G, Vogl T, Cunha FQ, Alves-Filho JC, Cunha TM. S100A9 plays a pivotal role in a mouse model of herpetic neuralgia via TLR4/TNF pathway. Brain, Behavior, and Immunity. PMID 32243898 DOI: 10.1016/J.Bbi.2020.03.033 |
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Dos Santos RS, Veras FP, Ferreira DW, Sant'Anna MB, Lollo PC, Cunha TM, Galdino G. Involvement of the Hsp70/TLR4/IL-6 and TNF-α pathways in delayed-onset muscle soreness. Journal of Neurochemistry. PMID 32173863 DOI: 10.1111/jnc.15006 |
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F Gomes FI, Cunha FQ, Cunha TM. Peripheral nitric oxide signaling directly blocks inflammatory pain. Biochemical Pharmacology. 113862. PMID 32081790 DOI: 10.1016/J.Bcp.2020.113862 |
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2020 |
Barbosa GM, Cunha JE, Russo TL, Cunha TM, Castro PATS, Oliveira FFB, Cunha FQ, Ramalho FS, Salvini TF. Thirty days after anterior cruciate ligament transection is sufficient to induce signs of knee osteoarthritis in rats: pain, functional impairment, and synovial inflammation. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 69: 279-288. PMID 32006078 DOI: 10.1007/S00011-020-01317-1 |
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2019 |
Fonseca MM, Davoli-Ferreira M, Santa-Cecília F, Guimarães RM, Oliveira FFB, Kusuda R, Ferreira DW, Alves-Filho JC, Cunha FQ, Cunha TM. IL-27 Counteracts Neuropathic Pain Development Through Induction of IL-10. Frontiers in Immunology. 10: 3059. PMID 32047492 DOI: 10.3389/Fimmu.2019.03059 |
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2019 |
Gonçalves WA, Rezende BM, de Oliveira MPE, Ribeiro LS, Fattori V, da Silva WN, Prazeres PHDM, Queiroz-Junior CM, Santana KTO, Costa WC, Beltrami VA, Costa VV, Birbrair A, Verri WA, Lopes F, ... Cunha TM, et al. Sensory Ganglia-Specific TNF Expression Is Associated With Persistent Nociception After Resolution of Inflammation. Frontiers in Immunology. 10: 3120. PMID 32038637 DOI: 10.3389/Fimmu.2019.03120 |
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2019 |
Kanashiro A, Hiroki CH, da Fonseca DM, Birbrair A, Ferreira RG, Bassi GS, Fonseca MD, Kusuda R, Cebinelli G, da Silva KP, Wanderley CW, Menezes GB, Filho JCA, Oliveira AG, Cunha TM, et al. THE ROLE OF NEUTROPHILS IN NEURO-IMMUNE MODULATION. Pharmacological Research. 104580. PMID 31786317 DOI: 10.1016/J.Phrs.2019.104580 |
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2019 |
Kusuda R, Carreira EU, Ulloa L, Cunha FQ, Kanashiro A, Cunha TM. Choline attenuates inflammatory hyperalgesia activating nitric oxide/cGMP/ATP-sensitive potassium channels pathway. Brain Research. 146567. PMID 31783002 DOI: 10.1016/J.Brainres.2019.146567 |
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2019 |
Ferreira DW, Ulecia-Morón C, Alvarado-Vázquez PA, Cunnane K, Moracho-Vilriales C, Grosick RL, Cunha TM, Romero-Sandoval EA. CD163 overexpression using a macrophage-directed gene therapy approach improves wound healing in ex vivo and in vivo human skin models. Immunobiology. PMID 31711674 DOI: 10.1016/j.imbio.2019.10.011 |
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2019 |
Barbosa GM, Cunha JE, Cunha TM, Martinho LB, Castro PATS, Oliveira FFB, Cunha FQ, Ramalho FS, Salvini TF. Clinical-like cryotherapy improves footprint patterns and reduces synovial inflammation in a rat model of post-traumatic knee osteoarthritis. Scientific Reports. 9: 14518. PMID 31601862 DOI: 10.1038/S41598-019-50958-8 |
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2019 |
de Castro-Jorge LA, de Carvalho RVH, Klein TM, Hiroki CH, Lopes AH, Guimarães RM, Fumagalli MJ, Floriano VG, Agostinho MR, Slhessarenko RD, Ramalho FS, Cunha TM, Cunha FQ, da Fonseca BAL, Zamboni DS. The NLRP3 inflammasome is involved with the pathogenesis of Mayaro virus. Plos Pathogens. 15: e1007934. PMID 31479495 DOI: 10.1371/Journal.Ppat.1007934 |
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2019 |
Fonseca RC, Bassi GS, Brito CC, Rosa LB, David BA, Araújo AM, Nóbrega N, Diniz AB, Jesus ICG, Barcelos LS, Fontes MAP, Bonaventura D, Kanashiro A, Cunha TM, Guatimosim S, et al. Vagus nerve regulates the phagocytic and secretory activity of resident macrophages in the liver. Brain, Behavior, and Immunity. PMID 31271871 DOI: 10.1016/j.bbi.2019.06.041 |
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2019 |
Guimarães RM, Davoli-Ferreira M, Fonseca MM, Damasceno LEA, Santa-Cecilia FV, Kusuda R, Menezes GB, Cunha FQ, Alves-Filho JC, Cunha TM. Frontline Science: Blood-circulating leukocytes fail to infiltrate the spinal cord parenchyma after spared nerve injury. Journal of Leukocyte Biology. PMID 31150565 DOI: 10.1002/Jlb.Hi1118-458R |
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2019 |
Borghi SM, Fattori V, Pinho-Ribeiro FA, Domiciano TP, Miranda-Sapla MM, Zaninelli TH, Casagrande R, Pinge-Filho P, Pavanelli WR, Alves-Filho JC, Cunha FQ, Cunha TM, Verri WA. Contribution of spinal cord glial cells to L. amazonensis experimental infection-induced pain in BALB/c mice. Journal of Neuroinflammation. 16: 113. PMID 31138231 DOI: 10.1186/S12974-019-1496-2 |
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Spiller F, de Oliveira Formiga R, Fernandes da Silva Coimbra J, Alves-Filho JC, Cunha TM, Cunha FQ. Targeting nitric oxide as a key modulator of sepsis, arthritis and pain. Nitric Oxide : Biology and Chemistry. PMID 31051258 DOI: 10.1016/J.Niox.2019.04.011 |
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2019 |
Lourenco-Gonzalez Y, Fattori V, Domiciano TP, Rossaneis AC, Borghi SM, Zaninelli TH, Bernardy CCF, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA. Repurposing of the Nootropic Drug Vinpocetine as an Analgesic and Anti-Inflammatory Agent: Evidence in a Mouse Model of Superoxide Anion-Triggered Inflammation. Mediators of Inflammation. 2019: 6481812. PMID 31049025 DOI: 10.1155/2019/6481812 |
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2019 |
Cunha JE, Barbosa GM, Castro PATS, Luiz BLF, Silva ACA, Russo TL, Vasilceac FA, Cunha TM, Cunha FQ, Salvini TF. Knee osteoarthritis induces atrophy and neuromuscular junction remodeling in the quadriceps and tibialis anterior muscles of rats. Scientific Reports. 9: 6366. PMID 31019213 DOI: 10.1038/S41598-019-42546-7 |
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2019 |
Wong DVT, Ribeiro-Filho HV, Wanderley CWS, Leite CAVG, Lima JB, Assef ANB, Cajado AG, Batista GLP, González RH, Silva KO, Borges LPC, Alencar NMN, Wilke DV, Cunha TM, Figueira ACM, et al. SN-38, the active metabolite of irinotecan, inhibits the acute inflammatory response by targeting toll-like receptor 4. Cancer Chemotherapy and Pharmacology. PMID 31011814 DOI: 10.1007/S00280-019-03844-Z |
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2019 |
Silva RL, Silveira GT, Wanderlei CW, Cecilio TN, Maganin AGM, Franchin M, Marques LMM, Lopes NP, Crippa JA, Guimarães FS, Alves-Filho JCF, Cunha FQ, Cunha TM. DMH-cannabidiol, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity by activating A receptor and inhibiting p38. Toxicology and Applied Pharmacology. PMID 30796934 DOI: 10.1016/J.Taap.2019.02.011 |
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2019 |
Pinto LG, Souza GR, Kusuda R, Lopes AH, Sant'Anna MB, Cunha FQ, Ferreira SH, Cunha TM. Non-Peptidergic Nociceptive Neurons Are Essential for Mechanical Inflammatory Hypersensitivity in Mice. Molecular Neurobiology. PMID 30674034 DOI: 10.1007/S12035-019-1494-5 |
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2018 |
Castanheira FVES, de Lima KA, Cebinelli GCM, Sônego F, Kanashiro A, Colon DF, Borges V, Czaikoski PG, Mota JM, Cunha TM, Alves-Filho JC, Liew FY, Cunha FQ. CCR5-Positive Inflammatory Monocytes are Crucial for Control of Sepsis. Shock (Augusta, Ga.). PMID 30724784 DOI: 10.1097/Shk.0000000000001301 |
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Lima KAd, Donate PB, Talbot J, Davoli-Ferreira M, Peres RS, Cunha TM, Alves-Filho JC, Cunha FQ. TGFβ1 signaling sustains aryl hydrocarbon receptor (AHR) expression and restrains the pathogenic potential of TH17 cells by an AHR-independent mechanism. Cell Death and Disease. 9: 1130-1130. PMID 30425241 DOI: 10.1038/S41419-018-1107-7 |
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2018 |
Manchope MF, Artero NA, Fattori V, Mizokami SS, Pitol DL, Issa JPM, Fukada SY, Cunha TM, Alves-Filho JC, Cunha FQ, Casagrande R, Verri WA. Naringenin mitigates titanium dioxide (TiO)-induced chronic arthritis in mice: role of oxidative stress, cytokines, and NFκB. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 67: 997-1012. PMID 30370484 DOI: 10.1007/S00011-018-1195-Y |
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Staurengo-Ferrari L, Ruiz-Miyazawa KW, Pinho-Ribeiro FA, Fattori V, Zaninelli TH, Badaro-Garcia S, Borghi SM, Carvalho TT, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA. -Chalcone Attenuates Pain and Inflammation in Experimental Acute Gout Arthritis in Mice. Frontiers in Pharmacology. 9: 1123. PMID 30333752 DOI: 10.3389/Fphar.2018.01123 |
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2018 |
Fattori V, Zarpelon AC, Staurengo-Ferrari L, Borghi SM, Zaninelli TH, Da Costa FB, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Arakawa NS, Verri WA. Budlein A, a Sesquiterpene Lactone From , Alleviates Pain and Inflammation in a Model of Acute Gout Arthritis in Mice. Frontiers in Pharmacology. 9: 1076. PMID 30319413 DOI: 10.3389/Fphar.2018.01076 |
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2018 |
Ruiz-Miyazawa KW, Staurengo-Ferrari L, Pinho-Ribeiro FA, Fattori V, Zaninelli TH, Badaro-Garcia S, Borghi SM, Andrade KC, Clemente-Napimoga JT, Alves-Filho JC, Cunha TM, Fraceto LF, Cunha FQ, Napimoga MH, Casagrande R, et al. 15d-PGJ-loaded nanocapsules ameliorate experimental gout arthritis by reducing pain and inflammation in a PPAR-gamma-sensitive manner in mice. Scientific Reports. 8: 13979. PMID 30228306 DOI: 10.1038/S41598-018-32334-0 |
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2018 |
Sonego AB, Prado DS, Vale GT, Sepulveda-Diaz JE, Cunha TM, Tirapelli CR, Del Bel EA, Raisman-Vozari R, Guimarães FS. Cannabidiol prevents haloperidol-induced vacuos chewing movements and inflammatory changes in mice via PPARγ receptors. Brain, Behavior, and Immunity. PMID 30217539 DOI: 10.1016/J.Bbi.2018.09.014 |
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2018 |
Santa-Cecília FV, Ferreira DW, Guimaraes RM, Cecilio NT, Fonseca MM, Lopes AH, Davoli-Ferreira M, Kusuda R, Souza GR, Nachbur U, Alves-Filho JC, Teixeira MM, Zamboni DS, Cunha FQ, Cunha TM. The NOD2 signaling in peripheral macrophages contributes to neuropathic pain development. Pain. PMID 30169421 DOI: 10.1097/J.Pain.0000000000001383 |
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Wanderley CW, Colon DF, Luiz JPM, Oliveira FF, Viacava PR, Leite CA, Pereira JA, Silva CM, Silva CR, Silva RL, Speck-Hernandez CA, Mota JM, Alves-Filho JC, Lima-Júnior RC, Cunha TM, et al. Paclitaxel reduces tumor growth by reprogramming tumor-associated macrophages to an M1- profile in a TLR4-dependent manner. Cancer Research. PMID 30104241 DOI: 10.1158/0008-5472.Can-17-3480 |
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Saraiva AL, Veras FP, Peres RS, Talbot J, de Lima KA, Luiz JP, Carballido JM, Cunha TM, Cunha FQ, Ryffel B, Alves-Filho JC. Succinate receptor deficiency attenuates arthritis by reducing dendritic cell traffic and expansion of T17 cells in the lymph nodes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800285. PMID 29894669 DOI: 10.1096/Fj.201800285 |
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Staurengo-Ferrari L, Trevelin SC, Fattori V, Nascimento DC, de Lima KA, Pelayo JS, Figueiredo F, Casagrande R, Fukada SY, Teixeira MM, Cunha TM, Liew FY, Oliveira RD, Louzada-Junior P, Cunha FQ, et al. Interleukin-33 Receptor (ST2) Deficiency Improves the Outcome of -Induced Septic Arthritis. Frontiers in Immunology. 9: 962. PMID 29867945 DOI: 10.3389/Fimmu.2018.00962 |
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Ruiz-Miyazawa KW, Pinho-Ribeiro FA, Borghi SM, Staurengo-Ferrari L, Fattori V, Amaral F, Teixeira MM, Alves-Filho JCF, Cunha TM, Cunha FQ, Casagrande R, Verri WA. Hesperidin methylchalcone suppresses experimental gout arthritis in mice by inhibiting NF-kB activation. Journal of Agricultural and Food Chemistry. PMID 29852732 DOI: 10.1021/Acs.Jafc.8B00959 |
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Rocha LW, Sonza DR, Broering MF, Nunes R, de Campos-Buzzi F, Corrêa R, Silva RL, Cunha TM, Santin JR, Quintão NLM. Synthetic chalcones as potential tool for acute- and chronic-pain control. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 104: 437-450. PMID 29787991 DOI: 10.1016/j.biopha.2018.05.075 |
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Silva MC, Davoli-Ferreira M, Medina TS, Sesti-Costa R, Silva GK, Lopes CD, Cardozo LE, Gava FN, Lyroni K, Dias FC, Frade AF, Baron M, Nakaya HI, Figueiredo F, Alves-Filho JC, ... ... Cunha TM, et al. Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis. Nature Communications. 9: 1513. PMID 29666415 DOI: 10.1038/S41467-018-03986-3 |
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Bassi GS, Ulloa L, Santos VR, Del Vecchio F, Delfino-Pereira P, Rodrigues GJ, Castania JA, Cunha FQ, Salgado HC, Cunha TM, Garcia-Cairasco N, Kanashiro A. Cortical stimulation in conscious rats controls joint inflammation. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29522782 DOI: 10.1016/J.Pnpbp.2018.02.013 |
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Peres RS, Donate PB, Talbot J, Cecilio NT, Lobo PR, Machado CC, Lima KWA, Oliveira RD, Carregaro V, Nakaya HI, Cunha TM, Alves-Filho JC, Liew FY, Louzada-Junior P, Cunha FQ. TGF-β signalling defect is linked to low CD39 expression on regulatory T cells and methotrexate resistance in rheumatoid arthritis. Journal of Autoimmunity. PMID 29426578 DOI: 10.1016/J.Jaut.2018.01.004 |
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2017 |
Castanheira FVES, Borges V, Sônego F, Kanashiro A, Donate PB, Melo PH, Pallas K, Russo RC, Amaral FA, Teixeira MM, Ramalho FS, Cunha TM, Liew FY, Alves-Filho JC, Graham GJ, et al. The Atypical Chemokine Receptor ACKR2 is Protective Against Sepsis. Shock (Augusta, Ga.). PMID 29589840 DOI: 10.1097/Shk.0000000000000969 |
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Azevedo PO, Sena IFG, Andreotti JP, Carvalho-Tavares J, Alves-Filho JC, Cunha TM, Cunha FQ, Mintz A, Birbrair A. Pericytes modulate myelination in the central nervous system. Journal of Cellular Physiology. PMID 29215724 DOI: 10.1002/Jcp.26348 |
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Kanashiro A, Franchin M, Bassi GS, Reis Santana DA, Cunha TM, Cunha FQ, Ulloa L, Rodrigues GJ. Inhibition of spinal p38 MAPK prevents articular neutrophil infiltration in experimental arthritis via sympathetic activation. Fundamental & Clinical Pharmacology. 32: 155-162. PMID 29206314 DOI: 10.1111/Fcp.12338 |
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Fattori V, Hohmann MSN, Rossaneis AC, Manchope MF, Alves-Filho JC, Cunha TM, Cunha FQ, Verri WA. Targeting IL-33/ST2 signaling: regulation of immune function and analgesia. Expert Opinion On Therapeutic Targets. 21: 1141-1152. PMID 29076792 DOI: 10.1080/14728222.2017.1398734 |
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2017 |
Zarpelon AC, Fattori V, Souto FO, Pinto LG, Pinho-Ribeiro FA, Ruiz-Miyazawa KW, Turato WM, Cunha TM, Da Costa FB, Cunha FQ, Casagrande R, Arakawa NS, Verri WA. Erratum to: The Sesquiterpene Lactone, Budlein A, Inhibits Antigen-Induced Arthritis in Mice: Role of NF-κB and Cytokines. Inflammation. PMID 28879563 DOI: 10.1007/s10753-017-0663-9 |
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Zarpelon AC, Fattori V, Souto FO, Pinto LG, Pinho-Ribeiro FA, Ruiz-Miyazawa KW, Turato WM, Cunha TM, da Costa FB, Cunha FQ, Casagrande R, Arakawa NS, Verri WA. The Sesquiterpene Lactone, Budlein A, Inhibits Antigen-Induced Arthritis in Mice: Role of NF-κB and Cytokines. Inflammation. PMID 28780730 DOI: 10.1007/S10753-017-0642-1 |
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Santos-Almeida FM, Domingos-Souza G, Meschiari CA, Fávaro LC, Becari C, Castania JA, Lopes A, Cunha TM, Moraes DJA, Cunha FQ, Ulloa L, Kanashiro A, Tezini GCSV, Salgado HC. Carotid sinus nerve electrical stimulation in conscious rats attenuates systemic inflammation via chemoreceptor activation. Scientific Reports. 7: 6265. PMID 28740186 DOI: 10.1038/s41598-017-06703-0 |
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Bertozzi MM, Rossaneis AC, Fattori V, Longhi-Balbinot DT, Freitas A, Cunha FQ, Alves-Filho JC, Cunha TM, Casagrande R, Verri WA. Diosmin reduces chronic constriction injury-induced neuropathic pain in mice. Chemico-Biological Interactions. 273: 180-189. PMID 28625489 DOI: 10.1016/J.Cbi.2017.06.014 |
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Silva RL, Lopes AH, Guimarães RM, Cunha TM. CXCL1/CXCR2 signaling in pathological pain: Role in peripheral and central sensitization. Neurobiology of Disease. 105: 109-116. PMID 28587921 DOI: 10.1016/j.nbd.2017.06.001 |
0.815 |
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2017 |
Silva JR, Lopes AH, Talbot J, Cecilio NT, Rossato MF, Silva RL, Souza GR, Silva CR, Lucas G, Fonseca BA, Arruda E, Alves-Filho JC, Cunha FQ, Cunha TM. Neuro-immune-glia interactions in the sensory ganglia account for the development of acute herpetic neuralgia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28576938 DOI: 10.1523/Jneurosci.2233-16.2017 |
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2017 |
Zucoloto AZ, Manchope MF, Staurengo-Ferrari L, Pinho-Ribeiro FA, Zarpelon AC, Saraiva ALL, Cecílio TN, Alves-Filho JC, Cunha TM, Menezes GB, Cunha FQ, Casagrande R, Verri WA. Probucol attenuates lipopolysaccharide-induced leukocyte recruitment and inflammatory hyperalgesia: effect on NF-кB activation and cytokine production. European Journal of Pharmacology. PMID 28501577 DOI: 10.1016/j.ejphar.2017.05.016 |
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2017 |
Bassi GS, Dias DP, Franchin M, Talbot J, Reis DG, Menezes GB, Castania JA, Garcia-Cairasco N, Resstel L, Salgado HC, Cunha FQ, Cunha TM, Ulloa L, Kanashiro A. Modulation of Experimental Arthritis by Vagal Sensory and Central Brain Stimulation. Brain, Behavior, and Immunity. PMID 28392428 DOI: 10.1016/J.Bbi.2017.04.003 |
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2017 |
Zucoloto AZ, Manchope MF, Staurengo-Ferrari L, Alves-Filho JC, Cunha TM, Antunes MM, Menezes GB, Cunha FQ, Casagrande R, Verri WA. Probucol attenuates overt pain-like behavior and carrageenan-induced inflammatory hyperalgesia and leukocyte recruitment by inhibiting NF-кB activation and cytokine production without antioxidant effects. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 28386622 DOI: 10.1007/S00011-017-1040-8 |
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2017 |
Peres RS, Santos GB, Cecilio NT, Jabor VA, Niehues M, Torres BG, Buqui G, Silva CH, Costa TD, Lopes NP, Nonato MC, Ramalho FS, Louzada-Júnior P, Cunha TM, Cunha FQ, et al. Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis. Arthritis Research & Therapy. 19: 47. PMID 28270195 DOI: 10.1186/S13075-017-1236-X |
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2017 |
Fattori V, Serafim KG, Zarpelon AC, Borghi SM, Pinho-Ribeiro FA, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA. Differential regulation of oxidative stress and cytokine production by endothelin ET and ET receptors in superoxide anion-induced inflammation and pain in mice. Journal of Drug Targeting. 25: 264-274. PMID 27701898 DOI: 10.1080/1061186X.2016.1245308 |
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2016 |
Carregaro V, Napimoga MH, Peres RS, Benevides L, Sacramento LA, Pinto LG, Grespan R, Cunha TM, da Silva JS, Cunha FQ. Therapeutic Treatment of Arthritic Mice with 15-Deoxy Δ(12,14)-Prostaglandin J2 (15d-PGJ2) Ameliorates Disease through the Suppression of Th17 Cells and the Induction of CD4(+)CD25(-)FOXP3(+) Cells. Mediators of Inflammation. 2016: 9626427. PMID 27872515 DOI: 10.1155/2016/9626427 |
0.42 |
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2016 |
Franchin M, Colón DF, da Cunha MG, Castanheira FV, Saraiva AL, Bueno-Silva B, Alencar SM, Cunha TM, Rosalen PL. Neovestitol, an isoflavonoid isolated from Brazilian red propolis, reduces acute and chronic inflammation: involvement of nitric oxide and IL-6. Scientific Reports. 6: 36401. PMID 27819273 DOI: 10.1038/srep36401 |
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2016 |
Trevelin SC, Dos Santos CX, Ferreira RG, de Sá Lima L, Silva RL, Scavone C, Curi R, Alves-Filho JC, Cunha TM, Roxo-Júnior P, Cervi MC, Laurindo FR, Hothersall JS, Cobb AM, Zhang M, et al. Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state. Scientific Reports. 6: 34581. PMID 27698473 DOI: 10.1038/Srep34581 |
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2016 |
Guerrero AT, Pinto LG, Cunha FQ, Ferreira SH, Alves-Filho JC, Verri WA, Cunha TM. Mechanisms underlying the hyperalgesic responses triggered by joint activation of TLR4. Pharmacological Reports : Pr. 68: 1293-1300. PMID 27689757 DOI: 10.1016/J.Pharep.2016.08.006 |
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2016 |
Nascimento MS, Ferreira MD, Quirino GF, Maruyama SR, Krishnaswamy JK, Liu D, Berlink J, Fonseca DM, Zamboni DS, Carregaro V, Almeida RP, Cunha TM, Eisenbarth SS, Silva JS. NOD2-RIP2-mediated signalling contributes to shape adaptive immunity in visceral leishmaniasis. The Journal of Infectious Diseases. PMID 27651416 DOI: 10.1093/infdis/jiw446 |
0.8 |
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2016 |
Vilela FM, Oliveira FM, Vicentini FT, Casagrande R, Verri WA, Cunha TM, Fonseca MJ. Commercial sunscreen formulations: UVB irradiation stability and effect on UVB irradiation-induced skin oxidative stress and inflammation. Journal of Photochemistry and Photobiology. B, Biology. 163: 413-420. PMID 27627683 DOI: 10.1016/j.jphotobiol.2016.09.007 |
0.488 |
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2016 |
Silva DF, Alves CQ, Brandão HN, David JM, David JP, Silva RL, Franchin M, Cunha TM, Martins FT, Oliveira CM. Poligalen, a new coumarin from Polygala boliviensis, reduces the release of TNF and IL-6 independent of NF-kB downregulation. Fitoterapia. PMID 27491751 DOI: 10.1016/J.Fitote.2016.07.021 |
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2016 |
Franchin M, Rosalen PL, da Cunha MG, Silva RL, Colón DF, Bassi GS, de Alencar SM, Ikegaki M, Alves-Filho JC, Cunha FQ, Beutler JA, Cunha TM. Cinnamoyloxy-mammeisin Isolated from Geopropolis Attenuates Inflammatory Process by Inhibiting Cytokine Production: Involvement of MAPK, AP-1, and NF-κB. Journal of Natural Products. PMID 27367493 DOI: 10.1021/Acs.Jnatprod.6B00263 |
0.82 |
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2016 |
Longhi-Balbinot DT, Rossaneis AC, Pinho-Ribeiro FA, Bertozzi MM, Cunha FQ, Alves-Filho JC, Cunha TM, Peron JP, Miranda KM, Casagrande R, Verri WA. The nitroxyl donor, Angeli's salt, reduces chronic constriction injury-induced neuropathic pain. Chemico-Biological Interactions. PMID 27287419 DOI: 10.1016/J.Cbi.2016.06.009 |
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2016 |
Silva RL, Castanheira FV, Figueiredo JG, Bassi GS, Ferreira SH, Cunha FQ, Cunha TM, Kanashiro A. Pharmacological Beta-Adrenergic Receptor Activation Attenuates Neutrophil Recruitment by a Mechanism Dependent on Nicotinic Receptor and the Spleen. Inflammation. PMID 27262431 DOI: 10.1007/s10753-016-0372-9 |
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2016 |
Pinho-Ribeiro FA, Zarpelon AC, Mizokami SS, Borghi SM, Bordignon J, Silva RL, Cunha TM, Alves-Filho JC, Cunha FQ, Casagrande R, Verri WA. The citrus flavonone naringenin reduces lipopolysaccharide-induced inflammatory pain and leukocyte recruitment by inhibiting NF-κB activation. The Journal of Nutritional Biochemistry. 33: 8-14. PMID 27260463 DOI: 10.1016/J.Jnutbio.2016.03.013 |
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2016 |
Sant'Anna MB, Kusuda R, Bozzo TA, Bassi GS, Alves-Filho JC, Cunha FQ, Ferreira SH, Souza GR, Cunha TM. Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization. Scientific Reports. 6: 26955. PMID 27230787 DOI: 10.1038/Srep26955 |
0.822 |
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2016 |
Pinho-Ribeiro FA, Fattori V, Zarpelon AC, Borghi SM, Staurengo-Ferrari L, Carvalho TT, Alves-Filho JC, Cunha FQ, Cunha TM, Casagrande R, Verri WA. Pyrrolidine dithiocarbamate inhibits superoxide anion-induced pain and inflammation in the paw skin and spinal cord by targeting NF-κB and oxidative stress. Inflammopharmacology. 24: 97-107. PMID 27160222 DOI: 10.1007/s10787-016-0266-3 |
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2016 |
Bassi GS, do C Malvar D, Cunha TM, Cunha FQ, Kanashiro A. Spinal GABA-B receptor modulates neutrophil recruitment to the knee joint in zymosan-induced arthritis. Naunyn-Schmiedeberg's Archives of Pharmacology. 389: 851-61. PMID 27106212 DOI: 10.1007/s00210-016-1248-0 |
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2016 |
Kanashiro A, Talbot J, Peres RS, Pinto LG, Bassi GS, Cunha TM, de Q Cunha F. Neutrophil Recruitment and Articular Hyperalgesia in Antigen-Induced Arthritis is Modulated by the Cholinergic Anti-Inflammatory Pathway. Basic & Clinical Pharmacology & Toxicology. PMID 27098245 DOI: 10.1111/Bcpt.12611 |
0.76 |
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2016 |
Franchin M, Cólon DF, Castanheira FV, da Cunha MG, Bueno-Silva B, Alencar SM, Cunha TM, Rosalen PL. Vestitol Isolated from Brazilian Red Propolis Inhibits Neutrophils Migration in the Inflammatory Process: Elucidation of the Mechanism of Action. Journal of Natural Products. 79: 954-60. PMID 26938776 DOI: 10.1021/acs.jnatprod.5b00938 |
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2016 |
Santa-Cecília FV, Socias B, Ouidja MO, Sepulveda-Diaz JE, Acuña L, Silva RL, Michel PP, Del-Bel E, Cunha TM, Raisman-Vozari R. Doxycycline Suppresses Microglial Activation by Inhibiting the p38 MAPK and NF-kB Signaling Pathways. Neurotoxicity Research. 29: 447-59. PMID 26745968 DOI: 10.1007/s12640-015-9592-2 |
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2015 |
Lopes AH, Brandolini L, Aramini A, Bianchini G, Silva RL, Zaperlon AC, Verri WA, Alves-Filho JC, Cunha FQ, Teixeira MM, Allegretti M, Cunha TM. DF2755A, a novel non-competitive allosteric inhibitor of CXCR1/2, reduces inflammatory and post-operative pain. Pharmacological Research. PMID 26592483 DOI: 10.1016/J.Phrs.2015.11.005 |
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2015 |
Quadros AU, Pinto LG, Fonseca MM, Kusuda R, Cunha FQ, Cunha TM. Dynamic weight bearing is an efficient and predictable method for evaluation of arthritic nociception and its pathophysiological mechanisms in mice. Scientific Reports. 5: 14648. PMID 26511791 DOI: 10.1038/Srep14648 |
0.467 |
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2015 |
Veras FP, Peres RS, Saraiva AL, Pinto LG, Louzada-Junior P, Cunha TM, Paschoal JA, Cunha FQ, Alves-Filho JC. Fructose 1,6-bisphosphate, a high-energy intermediate of glycolysis, attenuates experimental arthritis by activating anti-inflammatory adenosinergic pathway. Scientific Reports. 5: 15171. PMID 26478088 DOI: 10.1038/Srep15171 |
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2015 |
Fattori V, Pinho-Ribeiro FA, Borghi SM, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA. Curcumin inhibits superoxide anion-induced pain-like behavior and leukocyte recruitment by increasing Nrf2 expression and reducing NF-κB activation. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 64: 993-1003. PMID 26456836 DOI: 10.1007/S00011-015-0885-Y |
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2015 |
Wong DV, Lima-Júnior RC, Carvalho CB, Borges VF, Wanderley CW, Bem AX, Leite CA, Teixeira MA, Batista GL, Silva RL, Cunha TM, Brito GA, Almeida PR, Cunha FQ, Ribeiro RA. The Adaptor Protein Myd88 Is a Key Signaling Molecule in the Pathogenesis of Irinotecan-Induced Intestinal Mucositis. Plos One. 10: e0139985. PMID 26440613 DOI: 10.1371/Journal.Pone.0139985 |
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2015 |
Pinto LG, Talbot J, Peres RS, Franca RF, Ferreira SH, Ryffel B, Aves-Filho JC, Figueiredo F, Cunha TM, Cunha FQ. Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production. Arthritis Research & Therapy. 17: 235. PMID 26330334 DOI: 10.1186/S13075-015-0759-2 |
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2015 |
Vaz ER, Fujimura PT, Araujo GR, da Silva CA, Silva RL, Cunha TM, Lopes-Ferreira M, Lima C, Ferreira MJ, Cunha-Junior JP, Taketomi EA, Goulart LR, Ueira-Vieira C. A Short Peptide That Mimics the Binding Domain of TGF-β1 Presents Potent Anti-Inflammatory Activity. Plos One. 10: e0136116. PMID 26312490 DOI: 10.1371/journal.pone.0136116 |
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2015 |
Zarpelon AC, Rodrigues FC, Lopes AH, Souza GR, Carvalho TT, Pinto LG, Xu D, Ferreira SH, Alves-Filho JC, McInnes IB, Ryffel B, Quesniaux VF, Reverchon F, Mortaud S, Menuet A, ... ... Cunha TM, et al. Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26310268 DOI: 10.1096/Fj.14-267146 |
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2015 |
Yamacita-Borin FY, Zarpelon AC, Pinho-Ribeiro FA, Fattori V, Alves-Filho JC, Cunha FQ, Cunha TM, Casagrande R, Verri WA. Superoxide anion-induced pain and inflammation depends on TNFα/TNFR1 signaling in mice. Neuroscience Letters. 605: 53-8. PMID 26291484 DOI: 10.1016/J.Neulet.2015.08.015 |
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2015 |
Serafim KG, Navarro SA, Zarpelon AC, Pinho-Ribeiro FA, Fattori V, Cunha TM, Alves-Filho JC, Cunha FQ, Casagrande R, Verri WA. Bosentan, a mixed endothelin receptor antagonist, inhibits superoxide anion-induced pain and inflammation in mice. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 26246053 DOI: 10.1007/S00210-015-1160-Z |
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2015 |
Fonseca MD, Cunha FQ, Kashfi K, Cunha TM. NOSH-aspirin (NBS-1120), a dual nitric oxide and hydrogen sulfide-releasing hybrid, reduces inflammatory pain. Pharmacology Research & Perspectives. 3: e00133. PMID 26236481 DOI: 10.1002/Prp2.133 |
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2015 |
Bassi GS, Brognara F, Castania JA, Talbot J, Cunha TM, Cunha FQ, Ulloa L, Kanashiro A, Dias DP, Salgado HC. Baroreflex activation in conscious rats modulates the joint inflammatory response via sympathetic function. Brain, Behavior, and Immunity. 49: 140-7. PMID 25986215 DOI: 10.1016/j.bbi.2015.05.002 |
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2015 |
Ruiz-Miyazawa KW, Pinho-Ribeiro FA, Zarpelon AC, Staurengo-Ferrari L, Silva RL, Alves-Filho JC, Cunha TM, Cunha FQ, Casagrande R, Verri WA. Vinpocetine reduces lipopolysaccharide-induced inflammatory pain and neutrophil recruitment in mice by targeting oxidative stress, cytokines and NF-κB. Chemico-Biological Interactions. 237: 9-17. PMID 25980587 DOI: 10.1016/J.Cbi.2015.05.007 |
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2015 |
Freitas CS, Roveda AC, Truzzi DR, Garcia AC, Cunha TM, Cunha FQ, Franco DW. Anti-inflammatory and Anti-nociceptive Activity of Ruthenium Complexes with Isonicotinic and Nicotinic Acids (Niacin) as Ligands. Journal of Medicinal Chemistry. 58: 4439-48. PMID 25973517 DOI: 10.1021/Acs.Jmedchem.5B00133 |
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2015 |
Parra RS, Lopes AH, Carreira EU, Feitosa MR, Cunha FQ, Garcia SB, Cunha TM, da Rocha JJ, Féres O. Hyperbaric oxygen therapy ameliorates TNBS-induced acute distal colitis in rats. Medical Gas Research. 5: 6. PMID 25926972 DOI: 10.1186/S13618-015-0026-2 |
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2015 |
Souza GR, Cunha TM, Silva RL, Lotufo CM, Verri WA, Funez MI, Villarreal CF, Talbot J, Sousa LP, Parada CA, Cunha FQ, Ferreira SH. Involvement of nuclear factor kappa B in the maintenance of persistent inflammatory hypernociception. Pharmacology, Biochemistry, and Behavior. 134: 49-56. PMID 25902407 DOI: 10.1016/J.Pbb.2015.04.005 |
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2015 |
Talbot J, Bianchini FJ, Nascimento DC, Oliveira RD, Souto FO, Pinto LG, Peres RS, Silva JR, Almeida SC, Louzada-Junior P, Cunha TM, Cunha FQ, Alves-Filho JC. CCR2 Expression in Neutrophils Plays a Critical Role in Their Migration Into the Joints in Rheumatoid Arthritis. Arthritis & Rheumatology (Hoboken, N.J.). 67: 1751-9. PMID 25779331 DOI: 10.1002/Art.39117 |
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2015 |
Borghi SM, Pinho-Ribeiro FA, Zarpelon AC, Cunha TM, Alves-Filho JC, Ferreira SH, Cunha FQ, Casagrande R, Verri WA. Interleukin-10 limits intense acute swimming-induced muscle mechanical hyperalgesia in mice. Experimental Physiology. 100: 531-44. PMID 25711612 DOI: 10.1113/Ep085026 |
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2015 |
Lopes AH, Talbot J, Silva RL, Lima JB, França RO, Verri WA, Mascarenhas DP, Ryffel B, Cunha FQ, Zamboni DS, Cunha TM. Peripheral NLCR4 inflammasome participates in the genesis of acute inflammatory pain. Pain. 156: 451-9. PMID 25687541 DOI: 10.1097/01.J.Pain.0000460322.72396.53 |
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2015 |
Peres RS, Liew FY, Talbot J, Carregaro V, Oliveira RD, Almeida SL, França RF, Donate PB, Pinto LG, Ferreira FI, Costa DL, Demarque DP, Gouvea DR, Lopes NP, Queiroz RH, ... ... Cunha TM, et al. Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America. 112: 2509-14. PMID 25675517 DOI: 10.1073/Pnas.1424792112 |
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2015 |
Silva RL, Lopes AH, França RO, Vieira SM, Silva EC, Amorim RC, Cunha FQ, Pohlit AM, Cunha TM. The quassinoid isobrucein B reduces inflammatory hyperalgesia and cytokine production by post-transcriptional modulation. Journal of Natural Products. 78: 241-9. PMID 25667960 DOI: 10.1021/Np500796F |
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2015 |
Carvalho TT, Borghi SM, Pinho-Ribeiro FA, Mizokami SS, Cunha TM, Ferreira SH, Cunha FQ, Casagrande R, Verri WA. Granulocyte-colony stimulating factor (G-CSF)-induced mechanical hyperalgesia in mice: Role for peripheral TNFα, IL-1β and IL-10. European Journal of Pharmacology. 749: 62-72. PMID 25584775 DOI: 10.1016/J.Ejphar.2014.12.023 |
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2014 |
Moriconi A, Cunha TM, Souza GR, Lopes AH, Cunha FQ, Carneiro VL, Pinto LG, Brandolini L, Aramini A, Bizzarri C, Bianchini G, Beccari AR, Fanton M, Bruno A, Costantino G, et al. Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief. Proceedings of the National Academy of Sciences of the United States of America. 111: 16937-42. PMID 25385614 DOI: 10.1073/Pnas.1417365111 |
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2014 |
Staurengo-Ferrari L, Zarpelon AC, Longhi-Balbinot DT, Marchesi M, Cunha TM, Alves-Filho JC, Cunha FQ, Ferreira SH, Casagrande R, Miranda KM, Verri WA. Nitroxyl inhibits overt pain-like behavior in mice: role of cGMP/PKG/ATP-sensitive potassium channel signaling pathway. Pharmacological Reports : Pr. 66: 691-8. PMID 24948073 DOI: 10.1016/J.Pharep.2014.04.003 |
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2014 |
Ivan AL, Campanini MZ, Martinez RM, Ferreira VS, Steffen VS, Vicentini FT, Vilela FM, Martins FS, Zarpelon AC, Cunha TM, Fonseca MJ, Baracat MM, Georgetti SR, Verri WA, Casagrande R. Pyrrolidine dithiocarbamate inhibits UVB-induced skin inflammation and oxidative stress in hairless mice and exhibits antioxidant activity in vitro. Journal of Photochemistry and Photobiology. B, Biology. 138: 124-33. PMID 24927233 DOI: 10.1016/j.jphotobiol.2014.05.010 |
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2014 |
Barragán-Iglesias P, Rocha-González HI, Pineda-Farias JB, Murbartián J, Godínez-Chaparro B, Reinach PS, Cunha TM, Cunha FQ, Granados-Soto V. Inhibition of peripheral anion exchanger 3 decreases formalin-induced pain. European Journal of Pharmacology. 738: 91-100. PMID 24877687 DOI: 10.1016/J.Ejphar.2014.05.029 |
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2014 |
Borghi SM, Zarpelon AC, Pinho-Ribeiro FA, Cardoso RD, Cunha TM, Alves-Filho JC, Ferreira SH, Cunha FQ, Casagrande R, Verri WA. Targeting interleukin-1β reduces intense acute swimming-induced muscle mechanical hyperalgesia in mice. The Journal of Pharmacy and Pharmacology. 66: 1009-20. PMID 24697255 DOI: 10.1111/Jphp.12226 |
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2014 |
Calil IL, Zarpelon AC, Guerrero AT, Alves-Filho JC, Ferreira SH, Cunha FQ, Cunha TM, Verri WA. Lipopolysaccharide induces inflammatory hyperalgesia triggering a TLR4/MyD88-dependent cytokine cascade in the mice paw. Plos One. 9: e90013. PMID 24595131 DOI: 10.1371/Journal.Pone.0090013 |
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2014 |
Vieira SM, Silva RL, Lemos HP, Amorim RC, Silva EC, Reinach PS, Cunha FQ, Pohlit AM, Cunha TM. Gastro-protective effects of isobrucein B, a quassinoid isolated from Picrolemma sprucei. Fitoterapia. 95: 8-15. PMID 24594240 DOI: 10.1016/J.Fitote.2014.02.008 |
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2014 |
Borghi SM, Zarpelon AC, Pinho-Ribeiro FA, Cardoso RD, Martins-Pinge MC, Tatakihara RI, Cunha TM, Ferreira SH, Cunha FQ, Casagrande R, Verri WA. Role of TNF-α/TNFR1 in intense acute swimming-induced delayed onset muscle soreness in mice. Physiology & Behavior. 128: 277-87. PMID 24518865 DOI: 10.1016/J.Physbeh.2014.01.023 |
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2013 |
de Luca B, Xavier-Elsas P, Barradas M, Luz RA, Queto T, Jones C, Arruda MA, Cunha TM, Cunha FQ, Gaspar-Elsas MI. Essential roles of PKA, iNOS, CD95/CD95L, and terminal caspases in suppression of eosinopoiesis by PGE2 and other cAMP-elevating agents. Thescientificworldjournal. 2013: 208705. PMID 24376378 DOI: 10.1155/2013/208705 |
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2013 |
Hohmann MS, Cardoso RD, Pinho-Ribeiro FA, Crespigio J, Cunha TM, Alves-Filho JC, da Silva RV, Pinge-Filho P, Ferreira SH, Cunha FQ, Casagrande R, Verri WA. 5-lipoxygenase deficiency reduces acetaminophen-induced hepatotoxicity and lethality. Biomed Research International. 2013: 627046. PMID 24288682 DOI: 10.1155/2013/627046 |
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2013 |
Souza GR, Talbot J, Lotufo CM, Cunha FQ, Cunha TM, Ferreira SH. Fractalkine mediates inflammatory pain through activation of satellite glial cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 11193-8. PMID 23776243 DOI: 10.1073/Pnas.1307445110 |
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2013 |
Vercelino R, Cunha TM, Ferreira ES, Cunha FQ, Ferreira SH, de Oliveira MG. Skin vasodilation and analgesic effect of a topical nitric oxide-releasing hydrogel. Journal of Materials Science. Materials in Medicine. 24: 2157-69. PMID 23756965 DOI: 10.1007/S10856-013-4973-7 |
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2013 |
dos Santos DS, Marta IE, Cárnio EC, de Quadros AU, Cunha TM, de Carvalho EC. Using an experimental model for the study of therapeutic touch. Revista Latino-Americana De Enfermagem. 21: 442-9. PMID 23546330 |
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2013 |
Zarpelon AC, Souza GR, Cunha TM, Schivo IR, Marchesi M, Casagrande R, Pinge-Filho P, Cunha FQ, Ferreira SH, Miranda KM, Verri WA. The nitroxyl donor, Angeli's salt, inhibits inflammatory hyperalgesia in rats. Neuropharmacology. 71: 1-9. PMID 23541720 DOI: 10.1016/J.Neuropharm.2013.03.009 |
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2013 |
Donate PB, Fornari TA, Macedo C, Cunha TM, Nascimento DC, Sakamoto-Hojo ET, Donadi EA, Cunha FQ, Passos GA. T cell post-transcriptional miRNA-mRNA interaction networks identify targets associated with susceptibility/resistance to collagen-induced arthritis. Plos One. 8: e54803. PMID 23359619 DOI: 10.1371/journal.pone.0054803 |
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2013 |
Figueiredo J, Ferreira AE, Silva RL, Ulloa L, Grieco P, Cunha TM, Ferreira SH, Cunha Fde Q, Kanashiro A. NDP-MSH inhibits neutrophil migration through nicotinic and adrenergic receptors in experimental peritonitis. Naunyn-Schmiedeberg's Archives of Pharmacology. 386: 311-8. PMID 23338711 DOI: 10.1007/s00210-013-0834-7 |
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2013 |
Guerrero AT, Zarpelon AC, Zaperlon AC, Vieira SM, Pinto LG, Ferreira SH, Cunha FQ, Verri WA, Cunha TM. The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia. Naunyn-Schmiedeberg's Archives of Pharmacology. 386: 51-9. PMID 23187752 DOI: 10.1007/S00210-012-0813-4 |
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2012 |
Franchin M, da Cunha MG, Denny C, Napimoga MH, Cunha TM, Koo H, de Alencar SM, Ikegaki M, Rosalen PL. Geopropolis from Melipona scutellaris decreases the mechanical inflammatory hypernociception by inhibiting the production of IL-1β and TNF-α. Journal of Ethnopharmacology. 143: 709-15. PMID 22885134 DOI: 10.1016/j.jep.2012.07.040 |
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|
2012 |
Trevelin SC, Alves-Filho JC, Sônego F, Turato W, Nascimento DC, Souto FO, Cunha TM, Gazzinelli RT, Cunha FQ. Toll-like receptor 9 activation in neutrophils impairs chemotaxis and reduces sepsis outcome. Critical Care Medicine. 40: 2631-7. PMID 22732279 DOI: 10.1097/CCM.0b013e318258fb70 |
0.422 |
|
2012 |
Mizokami SS, Arakawa NS, Ambrosio SR, Zarpelon AC, Casagrande R, Cunha TM, Ferreira SH, Cunha FQ, Verri WA. Kaurenoic acid from Sphagneticola trilobata Inhibits Inflammatory Pain: effect on cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway. Journal of Natural Products. 75: 896-904. PMID 22574649 DOI: 10.1021/Np200989T |
0.774 |
|
2012 |
Junqueira C, Guerrero AT, Galvão-Filho B, Andrade WA, Salgado AP, Cunha TM, Ropert C, Campos MA, Penido ML, Mendonça-Previato L, Previato JO, Ritter G, Cunha FQ, Gazzinelli RT. Trypanosoma cruzi adjuvants potentiate T cell-mediated immunity induced by a NY-ESO-1 based antitumor vaccine. Plos One. 7: e36245. PMID 22567144 DOI: 10.1371/Journal.Pone.0036245 |
0.404 |
|
2012 |
Vieira SM, Cunha TM, França RF, Pinto LG, Talbot J, Turato WM, Lemos HP, Lima JB, Verri WA, Almeida SC, Ferreira SH, Louzada-Junior P, Zamboni DS, Cunha FQ. Joint NOD2/RIPK2 signaling regulates IL-17 axis and contributes to the development of experimental arthritis. Journal of Immunology (Baltimore, Md. : 1950). 188: 5116-22. PMID 22491249 DOI: 10.4049/Jimmunol.1004190 |
0.772 |
|
2012 |
Zarpelon AC, Pinto LG, Cunha TM, Vieira SM, Carregaro V, Souza GR, Silva JS, Ferreira SH, Cunha FQ, Verri WA. Endothelin-1 induces neutrophil recruitment in adaptive inflammation via TNFα and CXCL1/CXCR2 in mice. Canadian Journal of Physiology and Pharmacology. 90: 187-99. PMID 22320712 DOI: 10.1139/Y11-116 |
0.729 |
|
2012 |
Cunha TM, Souza GR, Domingues AC, Carreira EU, Lotufo CM, Funez MI, Verri WA, Cunha FQ, Ferreira SH. Stimulation of peripheral kappa opioid receptors inhibits inflammatory hyperalgesia via activation of the PI3Kγ/AKT/nNOS/NO signaling pathway. Molecular Pain. 8: 10. PMID 22316281 DOI: 10.1186/1744-8069-8-10 |
0.811 |
|
2012 |
Pavao-de-Souza GF, Zarpelon AC, Tedeschi GC, Mizokami SS, Sanson JS, Cunha TM, Ferreira SH, Cunha FQ, Casagrande R, Verri WA. Acetic acid- and phenyl-p-benzoquinone-induced overt pain-like behavior depends on spinal activation of MAP kinases, PI(3)K and microglia in mice. Pharmacology, Biochemistry, and Behavior. 101: 320-8. PMID 22306747 DOI: 10.1016/J.Pbb.2012.01.018 |
0.731 |
|
2012 |
Donate PB, Cunha TM, Verri WA, Junta CM, Lima FO, Vieira SM, Peres RS, Bombonato-Prado KF, Louzada P, Ferreira SH, Donadi EA, Passos GA, Cunha FQ. Bosentan, an endothelin receptor antagonist, ameliorates collagen-induced arthritis: the role of TNF-α in the induction of endothelin system genes. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 61: 337-48. PMID 22249931 DOI: 10.1007/S00011-011-0415-5 |
0.745 |
|
2012 |
Guerrero AT, Cunha TM, Verri WA, Gazzinelli RT, Teixeira MM, Cunha FQ, Ferreira SH. Toll-like receptor 2/MyD88 signaling mediates zymosan-induced joint hypernociception in mice: participation of TNF-α, IL-1β and CXCL1/KC. European Journal of Pharmacology. 674: 51-7. PMID 22051147 DOI: 10.1016/J.Ejphar.2011.10.023 |
0.785 |
|
2012 |
Amaral FA, Costa VV, Tavares LD, Sachs D, Coelho FM, Fagundes CT, Soriani FM, Silveira TN, Cunha LD, Zamboni DS, Quesniaux V, Peres RS, Cunha TM, Cunha FQ, Ryffel B, et al. NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout. Arthritis and Rheumatism. 64: 474-84. PMID 21952942 DOI: 10.1002/Art.33355 |
0.748 |
|
2011 |
Carregaro V, Sá-Nunes A, Cunha TM, Grespan R, Oliveira CJ, Lima-Junior DS, Costa DL, Verri WA, Milanezi CM, Pham VM, Brand DD, Valenzuela JG, Silva JS, Ribeiro JM, Cunha FQ. Nucleosides from Phlebotomus papatasi salivary gland ameliorate murine collagen-induced arthritis by impairing dendritic cell functions. Journal of Immunology (Baltimore, Md. : 1950). 187: 4347-59. PMID 21930966 DOI: 10.4049/Jimmunol.1003404 |
0.647 |
|
2011 |
Souto FO, Zarpelon AC, Staurengo-Ferrari L, Fattori V, Casagrande R, Fonseca MJ, Cunha TM, Ferreira SH, Cunha FQ, Verri WA. Quercetin reduces neutrophil recruitment induced by CXCL8, LTB4, and fMLP: inhibition of actin polymerization. Journal of Natural Products. 74: 113-8. PMID 21275387 DOI: 10.1021/Np1003017 |
0.742 |
|
2011 |
Carvalho TT, Flauzino T, Otaguiri ES, Batistela AP, Zarpelon AC, Cunha TM, Ferreira SH, Cunha FQ, Verri WA. Granulocyte-colony stimulating factor (G-CSF) induces mechanical hyperalgesia via spinal activation of MAP kinases and PI3K in mice. Pharmacology, Biochemistry, and Behavior. 98: 188-95. PMID 21236293 DOI: 10.1016/J.Pbb.2010.12.027 |
0.729 |
|
2011 |
Donate PB, Fornari TA, Junta CM, Magalhães DA, Macedo C, Cunha TM, Nguyen C, Cunha FQ, Passos GA. Collagen induced arthritis (CIA) in mice features regulatory transcriptional network connecting major histocompatibility complex (MHC H2) with autoantigen genes in the thymus. Immunobiology. 216: 591-603. PMID 21168240 DOI: 10.1016/J.Imbio.2010.09.007 |
0.35 |
|
2010 |
Cunha TM, Talbot J, Pinto LG, Vieira SM, Souza GR, Guerrero AT, Sonego F, Verri WA, Zamboni DS, Ferreira SH, Cunha FQ. Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation. Molecular Pain. 6: 63. PMID 20920345 DOI: 10.1186/1744-8069-6-63 |
0.775 |
|
2010 |
Lima FO, Souza GR, Verri WA, Parada CA, Ferreira SH, Cunha FQ, Cunha TM. Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: involvement of the NO/cGMP/PKG/KATP signaling pathway. Pain. 151: 506-515. PMID 20813459 DOI: 10.1016/J.Pain.2010.08.014 |
0.756 |
|
2010 |
Figueiredo JG, Bitencourt FS, Cunha TM, Luz PB, Nascimento KS, Mota MRL, Sampaio AH, Cavada BS, Cunha FQ, Alencar NMN. Agglutinin isolated from the red marine alga Hypnea cervicornis J. Agardh reduces inflammatory hypernociception: Involvement of nitric oxide Pharmacology, Biochemistry and Behavior. 96: 371-377. PMID 20600247 DOI: 10.1016/J.Pbb.2010.06.008 |
0.516 |
|
2010 |
Verri WA, Souto FO, Vieira SM, Almeida SC, Fukada SY, Xu D, Alves-Filho JC, Cunha TM, Guerrero AT, Mattos-Guimaraes RB, Oliveira FR, Teixeira MM, Silva JS, McInnes IB, Ferreira SH, et al. IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Annals of the Rheumatic Diseases. 69: 1697-703. PMID 20472598 DOI: 10.1136/Ard.2009.122655 |
0.749 |
|
2010 |
Cunha TM, Roman-Campos D, Lotufo CM, Duarte HL, Souza GR, Verri WA, Funez MI, Dias QM, Schivo IR, Domingues AC, Sachs D, Chiavegatto S, Teixeira MM, Hothersall JS, Cruz JS, et al. Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 4442-7. PMID 20147620 DOI: 10.1073/Pnas.0914733107 |
0.795 |
|
2010 |
Pinto LG, Cunha TM, Vieira SM, Lemos HP, Verri WA, Cunha FQ, Ferreira SH. IL-17 mediates articular hypernociception in antigen-induced arthritis in mice. Pain. 148: 247-56. PMID 19969421 DOI: 10.1016/J.Pain.2009.11.006 |
0.769 |
|
2009 |
Valério DA, Georgetti SR, Magro DA, Casagrande R, Cunha TM, Vicentini FT, Vieira SM, Fonseca MJ, Ferreira SH, Cunha FQ, Verri WA. Quercetin reduces inflammatory pain: inhibition of oxidative stress and cytokine production. Journal of Natural Products. 72: 1975-9. PMID 19899776 DOI: 10.1021/Np900259Y |
0.788 |
|
2009 |
Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ. Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production. Proceedings of the National Academy of Sciences of the United States of America. 106: 5954-9. PMID 19289819 DOI: 10.1073/Pnas.0812782106 |
0.754 |
|
2009 |
Verri WA, Cunha TM, Magro DA, Guerrero AT, Vieira SM, Carregaro V, Souza GR, Henriques Md, Ferreira SH, Cunha FQ. Targeting endothelin ETA and ETB receptors inhibits antigen-induced neutrophil migration and mechanical hypernociception in mice. Naunyn-Schmiedeberg's Archives of Pharmacology. 379: 271-9. PMID 18854982 DOI: 10.1007/S00210-008-0360-1 |
0.755 |
|
2008 |
Dal-Secco D, Cunha TM, Freitas A, Alves-Filho JC, Souto FO, Fukada SY, Grespan R, Alencar NM, Neto AF, Rossi MA, Ferreira SH, Hothersall JS, Cunha FQ. Hydrogen sulfide augments neutrophil migration through enhancement of adhesion molecule expression and prevention of CXCR2 internalization: role of ATP-sensitive potassium channels. Journal of Immunology (Baltimore, Md. : 1950). 181: 4287-98. PMID 18768887 DOI: 10.4049/jimmunol.181.6.4287 |
0.688 |
|
2008 |
Cunha TM, Dal-Secco D, Verri WA, Guerrero AT, Souza GR, Vieira SM, Lotufo CM, Neto AF, Ferreira SH, Cunha FQ. Dual role of hydrogen sulfide in mechanical inflammatory hypernociception. European Journal of Pharmacology. 590: 127-35. PMID 18585702 DOI: 10.1016/J.Ejphar.2008.05.048 |
0.756 |
|
2008 |
Verri WA, Cunha TM, Magro DA, Domingues AC, Vieira SM, Souza GR, Liew FY, Ferreira SH, Cunha FQ. Role of IL-18 in overt pain-like behaviour in mice. European Journal of Pharmacology. 588: 207-12. PMID 18511039 DOI: 10.1016/J.Ejphar.2008.04.010 |
0.776 |
|
2008 |
Rocha FA, Leite AK, Pompeu MM, Cunha TM, Verri WA, Soares FM, Castro RR, Cunha FQ. Protective effect of an extract from Ascaris suum in experimental arthritis models. Infection and Immunity. 76: 2736-45. PMID 18411290 DOI: 10.1128/Iai.01085-07 |
0.617 |
|
2008 |
Carregaro V, Valenzuela JG, Cunha TM, Verri WA, Grespan R, Matsumura G, Ribeiro JM, Elnaiem DE, Silva JS, Cunha FQ. Phlebotomine salivas inhibit immune inflammation-induced neutrophil migration via an autocrine DC-derived PGE2/IL-10 sequential pathway. Journal of Leukocyte Biology. 84: 104-14. PMID 18390928 DOI: 10.1189/Jlb.1107797 |
0.677 |
|
2008 |
Cunha TM, Verri WA, Valério DA, Guerrero AT, Nogueira LG, Vieira SM, Souza DG, Teixeira MM, Poole S, Ferreira SH, Cunha FQ. Role of cytokines in mediating mechanical hypernociception in a model of delayed-type hypersensitivity in mice. European Journal of Pain (London, England). 12: 1059-68. PMID 18372199 DOI: 10.1016/J.Ejpain.2008.02.003 |
0.772 |
|
2008 |
Verri WA, Guerrero AT, Fukada SY, Valerio DA, Cunha TM, Xu D, Ferreira SH, Liew FY, Cunha FQ. IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 2723-8. PMID 18250323 DOI: 10.1073/Pnas.0712116105 |
0.756 |
|
2008 |
Cunha TM, Verri WA, Schivo IR, Napimoga MH, Parada CA, Poole S, Teixeira MM, Ferreira SH, Cunha FQ. Crucial role of neutrophils in the development of mechanical inflammatory hypernociception. Journal of Leukocyte Biology. 83: 824-32. PMID 18203872 DOI: 10.1189/Jlb.0907654 |
0.778 |
|
2008 |
Guerrero AT, Verri WA, Cunha TM, Silva TA, Schivo IR, Dal-Secco D, Canetti C, Rocha FA, Parada CA, Cunha FQ, Ferreira SH. Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE2. Journal of Leukocyte Biology. 83: 122-30. PMID 17913976 DOI: 10.1189/Jlb.0207123 |
0.767 |
|
2007 |
Verri WA, Cunha TM, Ferreira SH, Wei X, Leung BP, Fraser A, McInnes IB, Liew FY, Cunha FQ. IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production. European Journal of Immunology. 37: 3373-80. PMID 17979156 DOI: 10.1002/Eji.200737488 |
0.758 |
|
2007 |
Napimoga MH, Souza GR, Cunha TM, Ferrari LF, Clemente-Napimoga JT, Parada CA, Verri WA, Cunha FQ, Ferreira SH. 15d-prostaglandin J2 inhibits inflammatory hypernociception: involvement of peripheral opioid receptor. The Journal of Pharmacology and Experimental Therapeutics. 324: 313-21. PMID 17928570 DOI: 10.1124/Jpet.107.126045 |
0.808 |
|
2007 |
Cunha TM, Verri WA, Fukada SY, Guerrero AT, Santodomingo-Garzón T, Poole S, Parada CA, Ferreira SH, Cunha FQ. TNF-alpha and IL-1beta mediate inflammatory hypernociception in mice triggered by B1 but not B2 kinin receptor. European Journal of Pharmacology. 573: 221-9. PMID 17669394 DOI: 10.1016/J.Ejphar.2007.07.007 |
0.767 |
|
2007 |
Cunha TM, Verri WA. Hydrogen sulfide, is it a promise analgesic drug or another inflammatory pain mediator? Pain. 130: 300-302. PMID 17553618 DOI: 10.1016/j.pain.2007.04.036 |
0.537 |
|
2007 |
Valério DA, Cunha TM, Arakawa NS, Lemos HP, Da Costa FB, Parada CA, Ferreira SH, Cunha FQ, Verri WA. Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism. European Journal of Pharmacology. 562: 155-63. PMID 17320857 DOI: 10.1016/J.Ejphar.2007.01.029 |
0.78 |
|
2007 |
Verri WA, Cunha TM, Parada CA, Poole S, Liew FY, Ferreira SH, Cunha FQ. Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18. Brain Behavior and Immunity. 21: 535-543. PMID 17194566 DOI: 10.1016/J.Bbi.2006.11.005 |
0.768 |
|
2006 |
Guerrero AT, Verri WA, Cunha TM, Silva TA, Rocha FA, Ferreira SH, Cunha FQ, Parada CA. Hypernociception elicited by tibio-tarsal joint flexion in mice: a novel experimental arthritis model for pharmacological screening. Pharmacology, Biochemistry, and Behavior. 84: 244-51. PMID 16797062 DOI: 10.1016/J.Pbb.2006.05.008 |
0.75 |
|
2006 |
Verri WA, Cunha TM, Parada CA, Wei XQ, Ferreira SH, Liew FY, Cunha FQ. IL-15 mediates immune inflammatory hypernociception by triggering a sequential release of IFN-gamma, endothelin, and prostaglandin. Proceedings of the National Academy of Sciences of the United States of America. 103: 9721-5. PMID 16766656 DOI: 10.1073/Pnas.0603286103 |
0.762 |
|
2006 |
Verri WA, Cunha TM, Parada CA, Poole S, Cunha FQ, Ferreira SH. Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development? Pharmacology & Therapeutics. 112: 116-38. PMID 16730375 DOI: 10.1016/J.Pharmthera.2006.04.001 |
0.796 |
|
2005 |
Verri WA, Molina RO, Schivo IR, Cunha TM, Parada CA, Poole S, Ferreira SH, Cunha FQ. Nociceptive effect of subcutaneously injected interleukin-12 is mediated by endothelin (ET) acting on ETB receptors in rats. The Journal of Pharmacology and Experimental Therapeutics. 315: 609-15. PMID 16024732 DOI: 10.1124/Jpet.105.089409 |
0.762 |
|
2004 |
Verri WA, Schivo IR, Cunha TM, Liew FY, Ferreira SH, Cunha FQ. Interleukin-18 induces mechanical hypernociception in rats via endothelin acting on ETB receptors in a morphine-sensitive manner. The Journal of Pharmacology and Experimental Therapeutics. 310: 710-7. PMID 15075358 DOI: 10.1124/Jpet.103.063990 |
0.762 |
|
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