Gail E. Besner, M.D. - Publications

Affiliations: 
Nationwide Children's Hospital, Columbus, Ohio, United States 

98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Shelby RD, Cromeens B, Rager TM, Besner GE. Influence of Growth Factors on the Development of Necrotizing Enterocolitis. Clinics in Perinatology. 46: 51-64. PMID 30771819 DOI: 10.1016/J.Clp.2018.10.005  0.4
2018 Olson JK, Navarro JB, Allen JM, McCulloh CJ, Mashburn-Warren L, Wang Y, Varaljay VA, Bailey MT, Goodman SD, Besner GE. An Enhanced Lactobacillus reuteri Biofilm Formulation that Increases Protection Against Experimental Necrotizing Enterocolitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 29848024 DOI: 10.1152/Ajpgi.00078.2018  0.304
2018 Cromeens BP, Wang Y, Liu Y, Johnson J, Besner GE. Critical intestinal cells originate from the host in enteroid-derived tissue-engineered intestine. The Journal of Surgical Research. 223: 155-164. PMID 29433868 DOI: 10.1016/J.Jss.2017.11.015  0.306
2017 McCulloh CJ, Olson JK, Wang Y, Vu J, Gartner S, Besner GE. Evaluating the efficacy of different types of stem cells in preserving gut barrier function in necrotizing enterocolitis. The Journal of Surgical Research. 214: 278-285. PMID 28624056 DOI: 10.1016/J.Jss.2017.03.026  0.301
2017 Zhou Y, Wang Y, Olson J, Yang J, Besner GE. Heparin-binding EGF like growth factor promotes neuronal nitric oxide synthase expression and protects the enteric nervous system after necrotizing enterocolitis. Pediatric Research. PMID 28422949 DOI: 10.1038/Pr.2017.68  0.342
2016 Liu Y, Nelson T, Cromeens B, Rager T, Lannutti J, Johnson J, Besner GE. HB-EGF embedded in PGA/PLLA scaffolds via subcritical CO2 augments the production of tissue engineered intestine. Biomaterials. 103: 150-159. PMID 27380441 DOI: 10.1016/J.Biomaterials.2016.06.039  0.322
2015 Wei J, Zhou Y, Besner GE. Heparin-binding EGF-like growth factor and enteric neural stem cell transplantation in the prevention of experimental necrotizing enterocolitis in mice. Pediatric Research. 78: 29-37. PMID 25806717 DOI: 10.1038/Pr.2015.63  0.403
2015 Liu Y, Rager T, Johnson J, Enmark J, Besner GE. Enriched Intestinal Stem Cell Seeding Improves the Architecture of Tissue-Engineered Intestine. Tissue Engineering. Part C, Methods. PMID 25603285 DOI: 10.1089/Ten.Tec.2014.0389  0.313
2015 Besner GE. A pain in the NEC: research challenges and opportunities. Journal of Pediatric Surgery. 50: 23-9. PMID 25598088 DOI: 10.1016/J.Jpedsurg.2014.10.024  0.384
2014 Yang J, Su Y, Besner GE. Stem cell therapy for necrotizing enterocolitis: innovative techniques and procedures for pediatric translational research. Methods in Molecular Biology (Clifton, N.J.). 1213: 121-37. PMID 25173379 DOI: 10.1007/978-1-4939-1453-1_11  0.315
2014 Watkins DJ, Zhou Y, Matthews MA, Chen L, Besner GE. HB-EGF augments the ability of mesenchymal stem cells to attenuate intestinal injury. Journal of Pediatric Surgery. 49: 938-44; discussion 9. PMID 24888839 DOI: 10.1016/J.Jpedsurg.2014.01.030  0.387
2014 Chen CL, Yang J, James IO, Zhang HY, Besner GE. Heparin-binding epidermal growth factor-like growth factor restores Wnt/β-catenin signaling in intestinal stem cells exposed to ischemia/reperfusion injury. Surgery. 155: 1069-80. PMID 24856127 DOI: 10.1016/J.Surg.2014.01.013  0.43
2014 Su Y, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) promotes cell migration and adhesion via focal adhesion kinase. The Journal of Surgical Research. 189: 222-31. PMID 24703506 DOI: 10.1016/J.Jss.2014.02.055  0.381
2014 Yang J, Su Y, Zhou Y, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) therapy for intestinal injury: Application and future prospects. Pathophysiology : the Official Journal of the International Society For Pathophysiology / Isp. 21: 95-104. PMID 24345808 DOI: 10.1016/J.Pathophys.2013.11.008  0.44
2014 Wei J, Zhou Y, Besner G. Heparin-Binding EGF-like Growth Factor and Enteric Neural Stem Cell Transplantation Act Synergistically to Prevent Experimental Necrotizing Enterocolitis Journal of Surgical Research. 186: 623-624. DOI: 10.1016/J.Jss.2013.11.622  0.369
2013 Zhou Y, Yang J, Watkins DJ, Boomer LA, Matthews MA, Su Y, Besner GE. Enteric nervous system abnormalities are present in human necrotizing enterocolitis: potential neurotransplantation therapy. Stem Cell Research & Therapy. 4: 157. PMID 24423414 DOI: 10.1186/Scrt387  0.347
2013 Watkins DJ, Yang J, Matthews MA, Besner GE. Synergistic effects of HB-EGF and mesenchymal stem cells in a murine model of intestinal ischemia/reperfusion injury. Journal of Pediatric Surgery. 48: 1323-9. PMID 23845626 DOI: 10.1016/J.Jpedsurg.2013.03.032  0.409
2013 Matthews MA, Watkins D, Darbyshire A, Carson WE, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) protects the intestines from radiation therapy-induced intestinal injury. Journal of Pediatric Surgery. 48: 1316-22. PMID 23845625 DOI: 10.1016/J.Jpedsurg.2013.03.030  0.405
2013 Lutmer J, Watkins D, Chen CL, Velten M, Besner G. Heparin-binding epidermal growth factor-like growth factor attenuates acute lung injury and multiorgan dysfunction after scald burn. The Journal of Surgical Research. 185: 329-37. PMID 23777985 DOI: 10.1016/J.Jss.2013.05.064  0.389
2013 Matthews MA, Adler BH, Arnold MA, Kumar S, Carvalho R, Besner GE. Diffuse intestinal ganglioneuromatosis in a child. Journal of Pediatric Surgery. 48: 1129-33. PMID 23701793 DOI: 10.1016/J.Jpedsurg.2013.03.066  0.3
2013 Watkins DJ, Besner GE. The role of the intestinal microcirculation in necrotizing enterocolitis. Seminars in Pediatric Surgery. 22: 83-7. PMID 23611611 DOI: 10.1053/J.Sempedsurg.2013.01.004  0.345
2013 Su Y, Yang J, Besner GE. HB-EGF promotes intestinal restitution by affecting integrin-extracellular matrix interactions and intercellular adhesions. Growth Factors (Chur, Switzerland). 31: 39-55. PMID 23305395 DOI: 10.3109/08977194.2012.755966  0.349
2013 Yang J, Radulescu A, Chen CL, Zhang HY, James IO, Besner GE. Heparin-binding epidermal growth factor-like growth factor improves intestinal barrier function and reduces mortality in a murine model of peritonitis. Surgery. 153: 52-62. PMID 22703966 DOI: 10.1016/J.Surg.2012.04.002  0.404
2013 Zhou Y, Su Y, Yang J, Watkins D, Besner G. Heparin-Binding Egf-Like Growth Factor Promotes Enteric Neurogenesis Via the Preservation of Glial Integrity After Necrotizing Enterocolitis Journal of Surgical Research. 179: 318. DOI: 10.1016/J.Jss.2012.10.639  0.373
2012 Zhou Y, James I, Besner GE. Heparin-binding epidermal growth factor-like growth factor promotes murine enteric nervous system development and enteric neural crest cell migration. Journal of Pediatric Surgery. 47: 1865-73. PMID 23084199 DOI: 10.1016/J.Jpedsurg.2012.05.008  0.398
2012 Yang J, Watkins D, Chen CL, Bhushan B, Zhou Y, Besner GE. Heparin-binding epidermal growth factor-like growth factor and mesenchymal stem cells act synergistically to prevent experimental necrotizing enterocolitis. Journal of the American College of Surgeons. 215: 534-45. PMID 22819639 DOI: 10.1016/J.Jamcollsurg.2012.05.037  0.424
2012 Watkins DJ, Zhou Y, Chen CL, Darbyshire A, Besner GE. Heparin-binding epidermal growth factor-like growth factor protects mesenchymal stem cells. The Journal of Surgical Research. 177: 359-64. PMID 22658491 DOI: 10.1016/J.Jss.2012.05.016  0.44
2012 Huang G, Besner GE, Brigstock DR. Heparin-binding epidermal growth factor-like growth factor suppresses experimental liver fibrosis in mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 703-12. PMID 22330337 DOI: 10.1038/Labinvest.2012.3  0.33
2012 Chen CL, Yu X, James IO, Zhang HY, Yang J, Radulescu A, Zhou Y, Besner GE. Heparin-binding EGF-like growth factor protects intestinal stem cells from injury in a rat model of necrotizing enterocolitis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 331-44. PMID 22157721 DOI: 10.1038/Labinvest.2011.167  0.432
2012 Zhang HY, James I, Chen CL, Besner GE. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) preserves gut barrier function by blocking neutrophil-endothelial cell adhesion after hemorrhagic shock and resuscitation in mice. Surgery. 151: 594-605. PMID 22153812 DOI: 10.1016/J.Surg.2011.10.001  0.44
2012 Yu X, Radulescu A, Chen CL, James IO, Besner GE. Heparin-binding EGF-like growth factor protects pericytes from injury. The Journal of Surgical Research. 172: 165-76. PMID 20863525 DOI: 10.1016/J.Jss.2010.07.058  0.405
2012 Watkins D, Chen C, Besner G. Heparin-Binding EGF-Like Growth Factor (HB-EGF) Promotes Mesenchymal Stem Cell (MSC) Proliferation and Migration and Protects MSC from Injury Journal of Surgical Research. 172: 261. DOI: 10.1016/J.Jss.2011.11.427  0.408
2012 Watkins DJ, Zhang H, Besner GE. Synergistic effects of heparin-binding EGF-like growth factor and mesenchymal stem cells in a murine model of intestinal ischemia-reperfusion injury Journal of the American College of Surgeons. 215: S94. DOI: 10.1016/J.Jamcollsurg.2012.06.251  0.43
2012 Matthews MAB, Watkins DJ, Darbyshire A, Besner GE. Heparin-binding EGF-like growth factor protects the intestines from radiation therapy-induced intestinal injury Journal of the American College of Surgeons. 215. DOI: 10.1016/J.Jamcollsurg.2012.06.075  0.403
2011 Giannone PJ, Alcamo AA, Schanbacher BL, Nankervis CA, Besner GE, Bauer JA. Poly(ADP-ribose) polymerase-1: a novel therapeutic target in necrotizing enterocolitis. Pediatric Research. 70: 67-71. PMID 21399558 DOI: 10.1203/Pdr.0B013E31821928Ff  0.31
2011 Zhang HY, Radulescu A, Chen CL, Olson JK, Darbyshire AK, Besner GE. Mice overexpressing the gene for heparin-binding epidermal growth factor-like growth factor (HB-EGF) have increased resistance to hemorrhagic shock and resuscitation. Surgery. 149: 276-83. PMID 20965535 DOI: 10.1016/J.Surg.2010.08.003  0.411
2011 Radulescu A, Zhang HY, Chen CL, Chen Y, Zhou Y, Yu X, Otabor I, Olson JK, Besner GE. Heparin-binding EGF-like growth factor promotes intestinal anastomotic healing. The Journal of Surgical Research. 171: 540-50. PMID 20850767 DOI: 10.1016/J.Jss.2010.06.036  0.426
2011 Zhang HY, Radulescu A, Chen Y, Besner GE. HB-EGF improves intestinal microcirculation after hemorrhagic shock. The Journal of Surgical Research. 171: 218-25. PMID 20421109 DOI: 10.1016/J.Jss.2010.01.024  0.407
2011 Besner GE, Yang J, Watkins D, Zhou Y, Chen C. Heparin-Binding EGF-Like Growth Factor (HB-EGF): Can We Add this to Breast Milk in the Future to Prevent Necrotizing Enterocolitis Pediatric Research. 70: 2-2. DOI: 10.1038/Pr.2011.227  0.349
2011 Yang J, Chen C, Watkins D, Zhang H, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) and mesenchymal stem cells (MSC) act synergistically to prevent experimental necrotizing enterocolitis Journal of the American College of Surgeons. 213: S79-S80. DOI: 10.1016/J.Jamcollsurg.2011.06.187  0.416
2010 Radulescu A, Zhang HY, Yu X, Olson JK, Darbyshire AK, Chen Y, Besner GE. Heparin-binding epidermal growth factor-like growth factor overexpression in transgenic mice increases resistance to necrotizing enterocolitis. Journal of Pediatric Surgery. 45: 1933-9. PMID 20920709 DOI: 10.1016/J.Jpedsurg.2010.05.002  0.406
2010 James IA, Chen CL, Huang G, Zhang HY, Velten M, Besner GE. HB-EGF protects the lungs after intestinal ischemia/reperfusion injury. The Journal of Surgical Research. 163: 86-95. PMID 20599214 DOI: 10.1016/J.Jss.2010.03.062  0.388
2010 Christensen RD, Gordon PV, Besner GE. Can we cut the incidence of necrotizing enterocolitis in half--today? Fetal and Pediatric Pathology. 29: 185-98. PMID 20594142 DOI: 10.3109/15513815.2010.483874  0.345
2010 Radulescu A, Yu X, Orvets ND, Chen Y, Zhang HY, Besner GE. Deletion of the heparin-binding epidermal growth factor-like growth factor gene increases susceptibility to necrotizing enterocolitis. Journal of Pediatric Surgery. 45: 729-34. PMID 20385279 DOI: 10.1016/J.Jpedsurg.2009.06.035  0.407
2010 Chen CL, Mehta VB, Zhang HY, Wu D, Otabor I, Radulescu A, El-Assal ON, Feng J, Chen Y, Besner GE. Intestinal phenotype in mice overexpressing a heparin-binding EGF-like growth factor transgene in enterocytes. Growth Factors (Chur, Switzerland). 28: 82-97. PMID 19939201 DOI: 10.3109/08977190903407365  0.409
2010 Radulescu A, Zhang H, Chen C, Chen Y, Zhou Y, Olson J, Besner G. Expression Levels of Heparin-Binding EGF-Like Growth Factor Affect Intestinal Anastomotic Wound Healing Journal of Surgical Research. 158: 184-185. DOI: 10.1016/J.Jss.2009.11.051  0.396
2010 Radulescu A, Zhang H, Yu X, Olson JK, Darbyshire AK, Chen Y, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) overexpression in transgenic mice increases resistance to necrotizing enterocolitis Journal of the American College of Surgeons. 211: S73-S74. DOI: 10.1016/J.Jamcollsurg.2010.06.192  0.342
2009 Zhang HY, Radulescu A, Besner GE. Heparin-binding epidermal growth factor-like growth factor is essential for preservation of gut barrier function after hemorrhagic shock and resuscitation in mice. Surgery. 146: 334-9. PMID 19628093 DOI: 10.1016/J.Surg.2009.02.020  0.395
2009 Zhou Y, Brigstock D, Besner GE. Heparin-binding EGF-like growth factor is a potent dilator of terminal mesenteric arterioles. Microvascular Research. 78: 78-85. PMID 19389413 DOI: 10.1016/J.Mvr.2009.04.006  0.43
2009 Yu X, Radulescu A, Zorko N, Besner GE. Heparin-binding EGF-like growth factor increases intestinal microvascular blood flow in necrotizing enterocolitis. Gastroenterology. 137: 221-30. PMID 19361505 DOI: 10.1053/J.Gastro.2009.03.060  0.414
2009 Radulescu A, Zorko NA, Yu X, Besner GE. Preclinical neonatal rat studies of heparin-binding EGF-like growth factor in protection of the intestines from necrotizing enterocolitis. Pediatric Research. 65: 437-42. PMID 19127210 DOI: 10.1203/Pdr.0B013E3181994Fa0  0.385
2009 Radulescu A, Yu X, Zorko N, Orvets N, Khalfoun S, Besner G. 75. Prophylactic Therapy for Necrotizing Enterocolitis Using Heparin-Binding EGF-Like Growth Factor Journal of Surgical Research. 151: 205. DOI: 10.1016/J.Jss.2008.11.089  0.363
2009 Zhang H, Radulescu A, Chen Y, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) improves gut microcirculation after hemorrhagic shock and resuscitation (HS/R) in mice Journal of the American College of Surgeons. 209: S70. DOI: 10.1016/J.Jamcollsurg.2009.06.169  0.372
2009 Zhou Y, Radulescu A, Chen Y, Besner GE. Deletion of the heparin-binding EGF-like growth factor (HB-EGF) gene in mice impairs intestinal transit Journal of the American College of Surgeons. 209: S69. DOI: 10.1016/J.Jamcollsurg.2009.06.166  0.362
2008 Mehta VB, Zhou Y, Radulescu A, Besner GE. HB-EGF stimulates eNOS expression and nitric oxide production and promotes eNOS dependent angiogenesis. Growth Factors (Chur, Switzerland). 26: 301-15. PMID 18925469 DOI: 10.1080/08977190802393596  0.306
2008 El-Assal ON, Paddock H, Marquez A, Besner GE. Heparin-binding epidermal growth factor-like growth factor gene disruption is associated with delayed intestinal restitution, impaired angiogenesis, and poor survival after intestinal ischemia in mice. Journal of Pediatric Surgery. 43: 1182-90. PMID 18558204 DOI: 10.1016/J.Jpedsurg.2008.02.053  0.436
2008 Zhou Y, Besner GE. 57. Heparin-Binding EGF-Like Growth Factor Is a Potent Vasodilator of Terminal Mesenteric Arterioles Journal of Surgical Research. 144: 201. DOI: 10.1016/J.Jss.2007.12.066  0.373
2008 Radulescu A, Yu X, Chen Y, Besner GE. HB-EGF knockout mice have increased susceptibility to necrotizing enterocolitis Journal of the American College of Surgeons. 207: S54. DOI: 10.1016/J.Jamcollsurg.2008.06.115  0.366
2007 Mehta VB, Besner GE. HB-EGF promotes angiogenesis in endothelial cells via PI3-kinase and MAPK signaling pathways. Growth Factors (Chur, Switzerland). 25: 253-63. PMID 18092233 DOI: 10.1080/08977190701773070  0.354
2007 El-Assal ON, Radulescu A, Besner GE. Heparin-binding EGF-like growth factor preserves mesenteric microcirculatory blood flow and protects against intestinal injury in rats subjected to hemorrhagic shock and resuscitation. Surgery. 142: 234-42. PMID 17689691 DOI: 10.1016/J.Surg.2007.04.003  0.392
2007 Rocourt DV, Mehta VB, Wu D, Besner GE. Heparin-binding EGF-like growth factor decreases neutrophil-endothelial cell interactions. The Journal of Surgical Research. 141: 262-6. PMID 17574583 DOI: 10.1016/J.Jss.2007.01.004  0.361
2007 Rocourt DV, Mehta VB, Besner GE. Heparin-binding EGF-like growth factor decreases inflammatory cytokine expression after intestinal ischemia/reperfusion injury. The Journal of Surgical Research. 139: 269-73. PMID 17291530 DOI: 10.1016/J.Jss.2006.10.047  0.329
2007 Feng J, Besner GE. Heparin-binding epidermal growth factor-like growth factor promotes enterocyte migration and proliferation in neonatal rats with necrotizing enterocolitis. Journal of Pediatric Surgery. 42: 214-20. PMID 17208569 DOI: 10.1016/J.Jpedsurg.2006.09.055  0.439
2006 Feng J, El-Assal ON, Besner GE. Heparin-binding epidermal growth factor-like growth factor reduces intestinal apoptosis in neonatal rats with necrotizing enterocolitis. Journal of Pediatric Surgery. 41: 742-7; discussion 74. PMID 16567187 DOI: 10.1016/J.Jpedsurg.2005.12.020  0.397
2006 Feng J, El-Assal ON, Besner GE. Heparin-binding epidermal growth factor-like growth factor decreases the incidence of necrotizing enterocolitis in neonatal rats. Journal of Pediatric Surgery. 41: 144-9; discussion 14. PMID 16410124 DOI: 10.1016/J.Jpedsurg.2005.10.018  0.402
2006 Feng J, Mehta VB, El-Assal ON, Wu D, Besner GE. Tissue distribution and plasma clearance of heparin-binding EGF-like growth factor (HB-EGF) in adult and newborn rats. Peptides. 27: 1589-96. PMID 16364500 DOI: 10.1016/J.Peptides.2005.11.013  0.38
2006 Rocourt D, Mehta V, Besner G. Heparin-binding EGF-like growth factor (HB-EGF) reduces systemic pro-inflammatory cyokine production after intestinal ischemia-reperfusion injury Journal of Surgical Research. 130: 254-255. DOI: 10.1016/J.Jss.2005.11.267  0.41
2005 Martin AE, Luquette MH, Besner GE. Timing, route, and dose of administration of heparin-binding epidermal growth factor-like growth factor in protection against intestinal ischemia-reperfusion injury. Journal of Pediatric Surgery. 40: 1741-7. PMID 16291163 DOI: 10.1016/J.Jpedsurg.2005.07.064  0.414
2005 Feng J, El-Assal ON, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) and necrotizing enterocolitis. Seminars in Pediatric Surgery. 14: 167-74. PMID 16084404 DOI: 10.1053/J.Sempedsurg.2005.05.005  0.45
2005 El-Assal ON, Besner GE. HB-EGF enhances restitution after intestinal ischemia/reperfusion via PI3K/Akt and MEK/ERK1/2 activation. Gastroenterology. 129: 609-25. PMID 16083716 DOI: 10.1053/J.Gastro.2005.05.054  0.427
2005 Mehta VB, Besner GE. Heparin-binding epidermal growth factor-like growth factor inhibits cytokine-induced NF-kappa B activation and nitric oxide production via activation of the phosphatidylinositol 3-kinase pathway. Journal of Immunology (Baltimore, Md. : 1950). 175: 1911-8. PMID 16034135 DOI: 10.4049/Jimmunol.175.3.1911  0.32
2005 Provenzano AP, Besner GE, James PF, Harding PA. Heparin-binding EGF-like growth factor (HB-EGF) overexpression in transgenic mice downregulates insulin-like growth factor binding protein (IGFBP)-3 and -4 mRNA. Growth Factors (Chur, Switzerland). 23: 19-31. PMID 16019424 DOI: 10.1080/08977140512331344012  0.304
2004 El-Assal ON, Besner GE. Heparin-binding epidermal growth factor-like growth factor and intestinal ischemia-reperfusion injury. Seminars in Pediatric Surgery. 13: 2-10. PMID 14765365 DOI: 10.1053/J.Sempedsurg.2003.09.002  0.431
2003 Mehta VB, Besner GE. Inhibition of NF-kappa B activation and its target genes by heparin-binding epidermal growth factor-like growth factor. Journal of Immunology (Baltimore, Md. : 1950). 171: 6014-22. PMID 14634113 DOI: 10.4049/Jimmunol.171.11.6014  0.324
2003 Xia G, Rachfal AW, Martin AE, Besner GE. Upregulation of endogenous heparin-binding EGF-like growth factor (HB-EGF) expression after intestinal ischemia/reperfusion injury. Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. 16: 57-63. PMID 12746188 DOI: 10.1080/08941930390194389  0.377
2003 Xia G, Martin AE, Besner GE. Heparin-binding EGF-like growth factor downregulates expression of adhesion molecules and infiltration of inflammatory cells after intestinal ischemia/reperfusion injury. Journal of Pediatric Surgery. 38: 434-9. PMID 12632363 DOI: 10.1053/Jpsu.2003.50075  0.426
2002 Kuhn MA, Xia G, Mehta VB, Glenn S, Michalsky MP, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) decreases oxygen free radical production in vitro and in vivo. Antioxidants & Redox Signaling. 4: 639-46. PMID 12230876 DOI: 10.1089/15230860260220148  0.397
2002 Xia G, Martin AE, Michalsky MP, Besner GE. Heparin-binding EGF-like growth factor preserves crypt cell proliferation and decreases bacterial translocation after intestinal ischemia/reperfusion injury. Journal of Pediatric Surgery. 37: 1081-7; discussion 1. PMID 12077776 DOI: 10.1053/Jpsu.2002.33881  0.413
2002 Lara-Marquez ML, Mehta V, Michalsky MP, Fleming JB, Besner GE. Heparin-binding EGF-like growth factor down regulates proinflammatory cytokine-induced nitric oxide and inducible nitric oxide synthase production in intestinal epithelial cells. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 6: 142-52. PMID 11890738 DOI: 10.1006/Niox.2001.0393  0.376
2002 Cribbs RK, Harding PA, Luquette MH, Besner GE. Endogenous production of heparin-binding EGF-like growth factor during murine partial-thickness burn wound healing. The Journal of Burn Care & Rehabilitation. 23: 116-25. PMID 11882801 DOI: 10.1097/00004630-200203000-00008  0.357
2002 Michalsky MP, Lara-Marquez M, Chun L, Besner GE. Heparin-binding EGF-like growth factor is present in human amniotic fluid and breast milk. Journal of Pediatric Surgery. 37: 1-6. PMID 11781977 DOI: 10.1053/Jpsu.2002.29415  0.426
2001 Davis-Fleische KM, Brigstock DR, Besner GE. Site-directed mutagenesis of heparin-binding EGF-like growth factor (HB-EGF): analysis of O-glycosylation sites and properties. Growth Factors (Chur, Switzerland). 19: 127-43. PMID 11769972 DOI: 10.3109/08977190109001081  0.309
2001 Xia G, Lara-Marquez M, Luquette MH, Glenn S, Haque A, Besner GE. Heparin-binding EGF-like growth factor decreases inducible nitric oxide synthase and nitric oxide production after intestinal ischemia/reperfusion injury. Antioxidants & Redox Signaling. 3: 919-30. PMID 11761337 DOI: 10.1089/15230860152665073  0.387
2001 Michalsky MP, Kuhn A, Mehta V, Besner GE. Heparin-binding EGF-like growth factor decreases apoptosis in intestinal epithelial cells in vitro. Journal of Pediatric Surgery. 36: 1130-5. PMID 11479841 DOI: 10.1053/Jpsu.2001.25730  0.439
1999 Pillai SB, Hinman CE, Luquette MH, Nowicki PT, Besner GE. Heparin-binding epidermal growth factor-like growth factor protects rat intestine from ischemia/reperfusion injury. The Journal of Surgical Research. 87: 225-31. PMID 10600353 DOI: 10.1006/Jsre.1999.5764  0.422
1999 Harding PA, Davis-Fleischer KM, Crissman-Combs MA, Miller MT, Brigstock DR, Besner GE. Induction of anchorage independent growth by heparin-binding EGF-like growth factor (HB-EGF). Growth Factors (Chur, Switzerland). 17: 49-61. PMID 10495962 DOI: 10.3109/08977199909001062  0.394
1998 Pillai SB, Luquette MH, Nowicki PT, Besner GE. Segmental intestinal ischemia: an improved method of producing small bowel injury. Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. 11: 123-8. PMID 9700620 DOI: 10.3109/08941939809032191  0.336
1998 Pillai SB, Turman MA, Besner GE. Heparin-binding EGF-like growth factor is cytoprotective for intestinal epithelial cells exposed to hypoxia Journal of Pediatric Surgery. 33: 973-979. PMID 9694080 DOI: 10.1016/S0022-3468(98)90517-6  0.445
1998 Cribbs RK, Luquette MH, Besner GE. Acceleration of partial-thickness burn wound healing with topical application of heparin-binding EGF-like growth factor (HB-EGF) Journal of Burn Care and Rehabilitation. 19: 95-101. PMID 9556308 DOI: 10.1097/00004630-199803000-00002  0.39
1997 Downing MT, Brigstock DR, Luquette MH, Crissman-Combs M, Besner GE. Immunohistochemical localization of heparin-binding epidermal growth factor-like growth factor in normal skin and skin cancers Histochemical Journal. 29: 735-744. PMID 9429077 DOI: 10.1023/A:1026417202351  0.36
1996 Davis KM, Brigstock DR, Johnson PR, Crissman-Combs MA, McCarthy DW, Downing MT, Besner GE. Production of glycosylated heparin-binding EGF-like growth factor in HeLa cells using vaccinia virus Protein Expression and Purification. 8: 57-67. PMID 8812835 DOI: 10.1006/Prep.1996.0074  0.312
1996 Bensard DD, Beaver BL, Besner GE, Cooney DR. Small bowel injury in children after blunt abdominal trauma: is diagnostic delay important? The Journal of Trauma. 41: 476-83. PMID 8810966 DOI: 10.1097/00005373-199609000-00015  0.304
1996 Harding PA, Brigstock DR, Shen L, Crissman-Combs MA, Besner GE. Characterization of the gene encoding murine heparin-binding epidermal growth factor-like growth factor Gene. 169: 291-292. PMID 8647467 DOI: 10.1016/0378-1119(95)00861-6  0.325
1996 McCarthy DW, Downing MT, Brigstock DR, Luquette MH, Brown KD, Abad MS, Besner GE. Production of heparin-binding epidermal growth factor-like growth factor (HB-EGF) at sites of thermal injury in pediatric patients Journal of Investigative Dermatology. 106: 49-56. PMID 8592081 DOI: 10.1111/1523-1747.Ep12327214  0.411
1995 Kim GY, Besner GE, Steffen CL, McCarthy DW, Downing MT, Luquette MH, Abad MS, Brigstock DR. Purification of heparin-binding epidermal growth factor-like growth factor from pig uterine luminal flushings, and its production by endometrial tissues Biology of Reproduction. 52: 561-571. PMID 7538797 DOI: 10.1095/Biolreprod52.3.561  0.371
1992 Besner GE, Whelton D, Crissman-Combs MA, Steffen CL, Kim GY, Brigstock DR. Interaction of heparin-binding EGF-like growth factor (HB-EGF) with the epidermal growth factor receptor: Modulation by heparin, heparinase, or synthetic heparin-binding HB-EGF fragments Growth Factors. 7: 289-296. PMID 1306684 DOI: 10.3109/08977199209046411  0.363
1991 Besner G, Higashiyama S, Klagsbrun M. Isolation and characterization of a macrophage-derived heparin-binding growth factor. Cell Regulation. 1: 811-9. PMID 2088527 DOI: 10.1091/Mbc.1.11.811  0.349
1991 Besner GE, Klagsbrun M. Macrophages secrete a heparin-binding inhibitor of endothelial cell growth Microvascular Research. 42: 187-197. PMID 1719354 DOI: 10.1016/0026-2862(91)90086-Q  0.327
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