Jorge E Contreras, PhD - Publications

2020- Physiology & Membrane Biology University of California, Davis, Davis, CA 
Large Pore Channels, Connexins, Pannexin, Gap Junction Channels, Connexin Hemichannels, Cardiac Physiology, Arrhythmias

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Jiang W, Lin YC, Botello-Smith W, Contreras J, Harris AL, Maragliano L, Luo YL. Free energy and kinetics of cAMP permeation through connexin26 via applied voltage and milestoning. Biophysical Journal. PMID 34214529 DOI: 10.1016/j.bpj.2021.06.024  0.494
2021 Gaete PS, Contreras JE. A method for assessing ionic and molecular permeation in connexin hemichannels. Methods in Enzymology. 654: 271-293. PMID 34120717 DOI: 10.1016/bs.mie.2021.01.009  0.377
2021 Seo JH, Dalal MS, Contreras JE. Pannexin-1 Channels as Mediators of Neuroinflammation. International Journal of Molecular Sciences. 22. PMID 34068881 DOI: 10.3390/ijms22105189  0.311
2021 Narahari AK, Kreutzberger AJB, Gaete PS, Chiu YH, Leonhardt SA, Medina CB, Jin X, Oleniacz PW, Kiessling V, Barrett PQ, Ravichandran KS, Yeager M, Contreras JE, Tamm LK, Bayliss D. ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels. Elife. 10. PMID 33410749 DOI: 10.7554/eLife.64787  0.442
2020 Gaete PS, Lillo MA, López W, Liu Y, Jiang W, Luo Y, Harris AL, Contreras JE. A novel voltage-clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels. The Journal of General Physiology. 152. PMID 33074302 DOI: 10.1085/jgp.202012607  0.552
2020 Naulin PA, Lozano B, Fuentes C, Liu Y, Schmidt C, Contreras JE, Barrera NP. Polydisperse molecular architecture of connexin 26/30 heteromeric hemichannels revealed by AFM imaging. The Journal of Biological Chemistry. PMID 32887797 DOI: 10.1074/Jbc.Ra119.012128  0.422
2020 Seo JH, Dalal MS, Calderon F, Contreras JE. Myeloid Pannexin-1 mediates acute leukocyte infiltration and leads to worse outcomes after brain trauma. Journal of Neuroinflammation. 17: 245. PMID 32819386 DOI: 10.1186/s12974-020-01917-y  0.353
2020 Gaete PS, Contreras JE. Taking a close look at a large-pore channel. Elife. 9. PMID 32228857 DOI: 10.7554/eLife.56114  0.369
2019 Gaete PS, Contreras JE. Uncoupled permeation through large-pore channels: ions and molecules don't always ride together. The Journal of Physiology. PMID 31785170 DOI: 10.1113/JP279263  0.31
2018 Valdez Capuccino JM, Chatterjee P, García IE, Botello-Smith WM, Zhang H, Harris AL, Luo Y, Contreras JE. The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening. The Journal of General Physiology. PMID 30530766 DOI: 10.1085/Jgp.201812219  0.502
2018 García IE, Villanelo F, Contreras GF, Pupo A, Pinto BI, Contreras JE, Pérez-Acle T, Alvarez O, Latorre R, Martínez AD, González C. The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels. The Journal of General Physiology. PMID 29643172 DOI: 10.1085/Jgp.201711782  0.308
2018 Garg C, Seo JH, Ramachandran J, Loh JM, Calderon F, Contreras JE. Trovafloxacin attenuates neuroinflammation and improves outcome after traumatic brain injury in mice. Journal of Neuroinflammation. 15: 42. PMID 29439712 DOI: 10.1186/s12974-018-1069-9  0.306
2016 Lopez W, Ramachandran J, Alsamarah A, Luo Y, Harris AL, Contreras JE. Mechanism of gating by calcium in connexin hemichannels. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872296 DOI: 10.1073/Pnas.1609378113  0.509
2015 Tong X, Lopez W, Ramachandran J, Ayad WA, Liu Y, Lopez-Rodriguez A, Harris AL, Contreras JE. Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules. The Journal of General Physiology. 146: 245-54. PMID 26324677 DOI: 10.1085/Jgp.201511375  0.582
2015 García IE, Maripillán J, Jara O, Ceriani R, Palacios-Muñoz A, Ramachandran J, Olivero P, Perez-Acle T, González C, Sáez JC, Contreras JE, Martínez AD. Keratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43. The Journal of Investigative Dermatology. 135: 1338-47. PMID 25625422 DOI: 10.1038/Jid.2015.20  0.531
2014 Harris AL, Contreras JE. Motifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensing. Frontiers in Physiology. 5: 113. PMID 24744733 DOI: 10.3389/Fphys.2014.00113  0.612
2014 Lopez W, Liu Y, Harris AL, Contreras JE. Divalent regulation and intersubunit interactions of human connexin26 (Cx26) hemichannels. Channels (Austin, Tex.). 8: 1-4. PMID 24126106 DOI: 10.4161/Chan.26789  0.444
2013 Lopez W, Gonzalez J, Liu Y, Harris AL, Contreras JE. Insights on the mechanisms of Ca(2+) regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y). The Journal of General Physiology. 142: 23-35. PMID 23797420 DOI: 10.1085/Jgp.201210893  0.514
2013 Miranda P, Contreras JE, Plested AJ, Sigworth FJ, Holmgren M, Giraldez T. State-dependent FRET reports calcium- and voltage-dependent gating-ring motions in BK channels. Proceedings of the National Academy of Sciences of the United States of America. 110: 5217-22. PMID 23479636 DOI: 10.1073/Pnas.1219611110  0.399
2010 Contreras JE, Chen J, Lau AY, Jogini V, Roux B, Holmgren M. Voltage profile along the permeation pathway of an open channel. Biophysical Journal. 99: 2863-9. PMID 21044583 DOI: 10.1016/J.Bpj.2010.08.053  0.323
2008 Contreras JE, Srikumar D, Holmgren M. Gating at the selectivity filter in cyclic nucleotide-gated channels. Proceedings of the National Academy of Sciences of the United States of America. 105: 3310-4. PMID 18287006 DOI: 10.1073/Pnas.0709809105  0.362
2006 Contreras JE, Holmgren M. Access of quaternary ammonium blockers to the internal pore of cyclic nucleotide-gated channels: implications for the location of the gate. The Journal of General Physiology. 127: 481-94. PMID 16606688 DOI: 10.1085/Jgp.200509440  0.423
2004 Contreras JE, Sánchez HA, Véliz LP, Bukauskas FF, Bennett MV, Sáez JC. Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue. Brain Research. Brain Research Reviews. 47: 290-303. PMID 15572178 DOI: 10.1016/J.Brainresrev.2004.08.002  0.7
2003 Contreras JE, Sáez JC, Bukauskas FF, Bennett MV. Functioning of cx43 hemichannels demonstrated by single channel properties. Cell Communication & Adhesion. 10: 245-9. PMID 14681024 DOI: 10.1080/Cac.10.4-6.245.249  0.7
2003 Bennett MV, Contreras JE, Bukauskas FF, Sáez JC. New roles for astrocytes: gap junction hemichannels have something to communicate. Trends in Neurosciences. 26: 610-7. PMID 14585601 DOI: 10.1016/J.Tins.2003.09.008  0.707
2003 Contreras JE, Sáez JC, Bukauskas FF, Bennett MV. Gating and regulation of connexin 43 (Cx43) hemichannels. Proceedings of the National Academy of Sciences of the United States of America. 100: 11388-93. PMID 13130072 DOI: 10.1073/Pnas.1434298100  0.689
2003 Sáez JC, Contreras JE, Bukauskas FF, Retamal MA, Bennett MV. Gap junction hemichannels in astrocytes of the CNS. Acta Physiologica Scandinavica. 179: 9-22. PMID 12940934 DOI: 10.1046/J.1365-201X.2003.01196.X  0.674
2002 Branes MC, Contreras JE, Sáez JC. Activation of human polymorphonuclear cells induces formation of functional gap junctions and expression of connexins. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 8: BR313-23. PMID 12165735  0.531
2002 De Maio A, Vega VL, Contreras JE. Gap junctions, homeostasis, and injury. Journal of Cellular Physiology. 191: 269-82. PMID 12012322 DOI: 10.1002/jcp.10108  0.346
2002 Contreras JE, Sánchez HA, Eugenin EA, Speidel D, Theis M, Willecke K, Bukauskas FF, Bennett MV, Sáez JC. Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture. Proceedings of the National Academy of Sciences of the United States of America. 99: 495-500. PMID 11756680 DOI: 10.1073/Pnas.012589799  0.637
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