Dorothy P. Schafer, Ph.D. - Publications

Affiliations: 
Neurobiology UMASS Medical School, Worcester, MA, United States 

32/60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Faust TE, Lee YH, O'Connor CD, Boyle MA, Gunner G, Badimon A, Ayata P, Schaefer A, Schafer DP. Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling. Biorxiv : the Preprint Server For Biology. PMID 38370645 DOI: 10.1101/2024.02.08.579178  0.381
2024 Durán Laforet V, Schafer DP. Microglia: Activity-dependent regulators of neural circuits. Annals of the New York Academy of Sciences. PMID 38294960 DOI: 10.1111/nyas.15105  0.4
2023 Zipp F, Bittner S, Schafer DP. Cytokines as emerging regulators of central nervous system synapses. Immunity. 56: 914-925. PMID 37163992 DOI: 10.1016/j.immuni.2023.04.011  0.351
2022 Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, ... ... Schafer DP, et al. Microglia states and nomenclature: A field at its crossroads. Neuron. 110: 3458-3483. PMID 36327895 DOI: 10.1016/j.neuron.2022.10.020  0.595
2022 Feinberg PA, Becker SC, Chung L, Ferrari L, Stellwagen D, Anaclet C, Durán-Laforet V, Faust TE, Sumbria RK, Schafer DP. Elevated TNF-α leads to neural circuit instability in the absence of Interferon Regulatory Factor 8. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35790400 DOI: 10.1523/JNEUROSCI.0601-22.2022  0.306
2021 Faust TE, Gunner G, Schafer DP. Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS. Nature Reviews. Neuroscience. PMID 34545240 DOI: 10.1038/s41583-021-00507-y  0.377
2020 Mondo E, Becker SC, Kautzman AG, Schifferer M, Baer CE, Chen J, Huang EJ, Simons M, Schafer DP. A developmental analysis of juxtavascular microglia dynamics and interactions with the vasculature. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32661024 DOI: 10.1523/Jneurosci.3006-19.2020  0.772
2019 Werneburg S, Jung J, Kunjamma RB, Ha SK, Luciano NJ, Willis CM, Gao G, Biscola NP, Havton LA, Crocker SJ, Popko B, Reich DS, Schafer DP. Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease. Immunity. PMID 31883839 DOI: 10.1016/J.Immuni.2019.12.004  0.689
2019 Schirmer L, Velmeshev D, Holmqvist S, Kaufmann M, Werneburg S, Jung D, Vistnes S, Stockley JH, Young A, Steindel M, Tung B, Goyal N, Bhaduri A, Mayer S, Engler JB, ... ... Schafer DP, et al. Neuronal vulnerability and multilineage diversity in multiple sclerosis. Nature. PMID 31316211 DOI: 10.1038/S41586-019-1404-Z  0.342
2019 Gunner G, Cheadle L, Johnson KM, Ayata P, Badimon A, Mondo E, Nagy MA, Liu L, Bemiller SM, Kim KW, Lira SA, Lamb BT, Tapper AR, Ransohoff RM, Greenberg ME, ... ... Schafer DP, et al. Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling. Nature Neuroscience. PMID 31209379 DOI: 10.1038/S41593-019-0419-Y  0.783
2019 Baror R, Neumann B, Segel M, Chalut KJ, Fancy SPJ, Schafer DP, Franklin RJM. Transforming growth factor-beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors. Glia. PMID 30861188 DOI: 10.1002/Glia.23612  0.341
2019 Anderson SR, Zhang J, Steele MR, Romero CO, Kautzman AG, Schafer DP, Vetter ML. Complement targets newborn retinal ganglion cells for phagocytic elimination by microglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30647151 DOI: 10.1523/Jneurosci.1854-18.2018  0.767
2018 Stevens B, Schafer DP. Roles of microglia in nervous system development, plasticity, and disease. Developmental Neurobiology. PMID 29704318 DOI: 10.1002/Dneu.22594  0.592
2017 Werneburg S, Feinberg PA, Johnson KM, Schafer DP. A microglia-cytokine axis to modulate synaptic connectivity and function. Current Opinion in Neurobiology. 47: 138-145. PMID 29096242 DOI: 10.1016/J.Conb.2017.10.002  0.791
2016 Schafer DP, Heller CT, Gunner G, Heller M, Gordon C, Hammond T, Wolf Y, Jung S, Stevens B. Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression. Elife. 5. PMID 27458802 DOI: 10.7554/Elife.15224  0.767
2016 Frost JL, Schafer DP. Microglia: Architects of the Developing Nervous System. Trends in Cell Biology. PMID 27004698 DOI: 10.1016/J.Tcb.2016.02.006  0.48
2016 Schafer DP, Heller CT, Gunner G, Heller M, Gordon C, Hammond T, Wolf Y, Jung S, Stevens B. Author response: Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression Elife. DOI: 10.7554/Elife.15224.019  0.729
2015 Ransohoff RM, Schafer D, Vincent A, Blachère NE, Bar-Or A. Neuroinflammation: Ways in Which the Immune System Affects the Brain. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 896-909. PMID 26306439 DOI: 10.1007/S13311-015-0385-3  0.431
2015 Schafer DP, Stevens B. Microglia Function in Central Nervous System Development and Plasticity. Cold Spring Harbor Perspectives in Biology. 7. PMID 26187728 DOI: 10.1101/Cshperspect.A020545  0.606
2015 Schafer DP, Stevens B. Brains, Blood, and Guts: MeCP2 Regulates Microglia, Monocytes, and Peripheral Macrophages. Immunity. 42: 600-2. PMID 25902477 DOI: 10.1016/J.Immuni.2015.04.002  0.533
2014 Schafer DP, Lehrman EK, Heller CT, Stevens B. An engulfment assay: a protocol to assess interactions between CNS phagocytes and neurons. Journal of Visualized Experiments : Jove. PMID 24962472 DOI: 10.3791/51482  0.589
2013 Schafer DP, Stevens B. Phagocytic glial cells: sculpting synaptic circuits in the developing nervous system. Current Opinion in Neurobiology. 23: 1034-40. PMID 24157239 DOI: 10.1016/J.Conb.2013.09.012  0.632
2013 Schafer DP, Lehrman EK, Stevens B. The "quad-partite" synapse: microglia-synapse interactions in the developing and mature CNS. Glia. 61: 24-36. PMID 22829357 DOI: 10.1002/Glia.22389  0.674
2012 Schafer DP, Lehrman EK, Kautzman AG, Koyama R, Mardinly AR, Yamasaki R, Ransohoff RM, Greenberg ME, Barres BA, Stevens B. Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner. Neuron. 74: 691-705. PMID 22632727 DOI: 10.1016/J.Neuron.2012.03.026  0.757
2012 Susuki K, Yuki N, Schafer DP, Hirata K, Zhang G, Funakoshi K, Rasband MN. Dysfunction of nodes of Ranvier: a mechanism for anti-ganglioside antibody-mediated neuropathies. Experimental Neurology. 233: 534-42. PMID 22178332 DOI: 10.1016/J.Expneurol.2011.11.039  0.541
2012 Schafer D, Lehrman EK, Kautzman AG, Koyama R, Mardinly AR, Greenberg ME, Barres BA, Stevens B. MICROGLIA AND THE COMPLEMENT CASCADE: SHAPING NEURAL CIRCUITS IN THE DEVELOPING BRAIN Schizophrenia Research. 136: S11-S12. DOI: 10.1016/S0920-9964(12)70039-7  0.723
2010 Schafer DP, Stevens B. Synapse elimination during development and disease: immune molecules take centre stage. Biochemical Society Transactions. 38: 476-81. PMID 20298206 DOI: 10.1042/Bst0380476  0.629
2009 Schafer DP, Jha S, Liu F, Akella T, McCullough LD, Rasband MN. Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 13242-54. PMID 19846712 DOI: 10.1523/Jneurosci.3376-09.2009  0.721
2006 Schafer DP, Rasband MN. Glial regulation of the axonal membrane at nodes of Ranvier. Current Opinion in Neurobiology. 16: 508-14. PMID 16945520 DOI: 10.1016/J.Conb.2006.08.003  0.568
2006 Ogawa Y, Schafer DP, Horresh I, Bar V, Hales K, Yang Y, Susuki K, Peles E, Stankewich MC, Rasband MN. Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5230-9. PMID 16687515 DOI: 10.1523/Jneurosci.0425-06.2006  0.585
2006 Schafer DP, Custer AW, Shrager P, Rasband MN. Early events in node of Ranvier formation during myelination and remyelination in the PNS. Neuron Glia Biology. 2: 69-79. PMID 16652168 DOI: 10.1017/S1740925X06000093  0.677
2004 Schafer DP, Bansal R, Hedstrom KL, Pfeiffer SE, Rasband MN. Does paranode formation and maintenance require partitioning of neurofascin 155 into lipid rafts? The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3176-85. PMID 15056697 DOI: 10.1523/Jneurosci.5427-03.2004  0.578
Low-probability matches (unlikely to be authored by this person)
2023 Stillman JM, Lopes FM, Lin JP, Hu K, Reich DS, Schafer DP. Lipofuscin-like autofluorescence within microglia and its impact on studying microglial engulfment. Biorxiv : the Preprint Server For Biology. PMID 36909485 DOI: 10.1101/2023.02.28.530224  0.299
2023 Stillman JM, Mendes Lopes F, Lin JP, Hu K, Reich DS, Schafer DP. Lipofuscin-like autofluorescence within microglia and its impact on studying microglial engulfment. Nature Communications. 14: 7060. PMID 37923732 DOI: 10.1038/s41467-023-42809-y  0.293
2014 Goldey GJ, Roumis DK, Glickfeld LL, Kerlin AM, Reid RC, Bonin V, Schafer DP, Andermann ML. Removable cranial windows for long-term imaging in awake mice. Nature Protocols. 9: 2515-38. PMID 25275789 DOI: 10.1038/Nprot.2014.165  0.281
2023 Lin JP, Brake A, Donadieu M, Lee A, Kawaguchi R, Sati P, Geschwind DH, Jacobson S, Schafer DP, Reich DS. A 4D transcriptomic map for the evolution of multiple sclerosis-like lesions in the marmoset brain. Biorxiv : the Preprint Server For Biology. PMID 37808784 DOI: 10.1101/2023.09.25.559371  0.253
2022 Jiang D, Burger CA, Akhanov V, Liang JH, Mackin RD, Albrecht NE, Andrade P, Schafer DP, Samuel MA. Neuronal signal-regulatory protein alpha drives microglial phagocytosis by limiting microglial interaction with CD47 in the retina. Immunity. PMID 36379210 DOI: 10.1016/j.immuni.2022.10.018  0.251
2023 Beccari S, Sierra-Torre V, Valero J, Pereira-Iglesias M, García-Zaballa M, Soria FN, De Las Heras-Garcia L, Carretero-Guillen A, Capetillo-Zarate E, Domercq M, Huguet PR, Ramonet D, Osman A, Han W, Dominguez C, ... ... Schafer D, et al. Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy. Autophagy. PMID 36622892 DOI: 10.1080/15548627.2023.2165313  0.25
2021 Schirmer L, Schafer DP, Bartels T, Rowitch DH, Calabresi PA. Diversity and Function of Glial Cell Types in Multiple Sclerosis. Trends in Immunology. PMID 33593693 DOI: 10.1016/j.it.2021.01.005  0.241
2022 Ivshina MP, van 't Spijker HM, Jung S, Ponny SR, Schafer DP, Richter JD. CPEB1 regulates the inflammatory immune response, phagocytosis, and alternative polyadenylation in microglia. Glia. PMID 35635122 DOI: 10.1002/glia.24222  0.23
2021 Absinta M, Maric D, Gharagozloo M, Garton T, Smith MD, Jin J, Fitzgerald KC, Song A, Liu P, Lin JP, Wu T, Johnson KR, McGavern DB, Schafer DP, Calabresi PA, et al. A lymphocyte-microglia-astrocyte axis in chronic active multiple sclerosis. Nature. PMID 34497421 DOI: 10.1038/s41586-021-03892-7  0.223
2020 Xie Z, Janczyk PŁ, Zhang Y, Liu A, Shi X, Singh S, Facemire L, Kubow K, Li Z, Jia Y, Schafer D, Mandell JW, Abounader R, Li H. A cytoskeleton regulator AVIL drives tumorigenesis in glioblastoma. Nature Communications. 11: 3457. PMID 32651364 DOI: 10.1038/S41467-020-17279-1  0.211
2023 Faust TE, Feinberg PA, Oâ Connor C, Kawaguchi R, Chan A, Strasburger H, Masuda T, Amann L, Knobeloch KP, Prinz M, Schaefer A, Schafer DP. A comparative analysis of microglial inducible Cre lines. Biorxiv : the Preprint Server For Biology. PMID 36711492 DOI: 10.1101/2023.01.09.523268  0.211
2009 Liu F, Schafer DP, McCullough LD. TTC, fluoro-Jade B and NeuN staining confirm evolving phases of infarction induced by middle cerebral artery occlusion. Journal of Neuroscience Methods. 179: 1-8. PMID 19167427 DOI: 10.1016/J.Jneumeth.2008.12.028  0.211
2023 Faust TE, Feinberg PA, O'Connor C, Kawaguchi R, Chan A, Strasburger H, Frosch M, Boyle MA, Masuda T, Amann L, Knobeloch KP, Prinz M, Schaefer A, Schafer DP. A comparative analysis of microglial inducible Cre lines. Cell Reports. 42: 113031. PMID 37635351 DOI: 10.1016/j.celrep.2023.113031  0.205
2022 Schafer DP, Stillman JM. Microglia are SYK of Aβ and cell debris. Cell. 185: 4043-4045. PMID 36306731 DOI: 10.1016/j.cell.2022.09.043  0.204
2023 Zhong J, Gunner G, Henninger N, Schafer DP, Bosco DA. Intravital Imaging of Fluorescent Protein Expression in Mice with a Closed-Skull Traumatic Brain Injury and Cranial Window Using a Two-Photon Microscope. Journal of Visualized Experiments : Jove. PMID 37154548 DOI: 10.3791/64701  0.203
2023 Funes S, Gadd DH, Mosqueda M, Zhong J, Jung J, Unger M, Cameron D, Dawes P, Keagle PJ, McDonough JA, Boopathy S, Sena-Esteves M, Lutz C, Skarnes WC, Lim ET, ... Schafer DP, et al. Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia. Biorxiv : the Preprint Server For Biology. PMID 37398081 DOI: 10.1101/2023.06.01.541136  0.201
2023 Robert SM, Reeves BC, Kiziltug E, Duy PQ, Karimy JK, Mansuri MS, Marlier A, Allington G, Greenberg ABW, DeSpenza T, Singh AK, Zeng X, Mekbib KY, Kundishora AJ, Nelson-Williams C, ... ... Schafer DP, et al. The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus. Cell. 186: 764-785.e21. PMID 36803604 DOI: 10.1016/j.cell.2023.01.017  0.189
2023 Wayne CR, Bremner L, Faust TE, Durán-Laforet V, Ampatey N, Ho SJ, Feinberg PA, Arvanitis P, Ciric B, Ruan C, Elyaman W, Delaney SL, Vargas WS, Swedo S, Menon V, ... Schafer DP, et al. Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis. Biorxiv : the Preprint Server For Biology. PMID 37215000 DOI: 10.1101/2023.03.10.532135  0.176
2020 Lowe PP, Morel C, Ambade A, Iracheta-Vellve A, Kwiatkowski E, Satishchandran A, Furi I, Cho Y, Gyongyosi B, Catalano D, Lefebvre E, Fischer L, Seyedkazemi S, Schafer DP, Szabo G. Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations. Journal of Neuroinflammation. 17: 296. PMID 33036616 DOI: 10.1186/s12974-020-01972-5  0.168
2021 Faust TE, Schafer DP. IL-6 boosts synaptogenesis STAT! Immunity. 54: 2444-2446. PMID 34758335 DOI: 10.1016/j.immuni.2021.10.010  0.152
1997 Mestecky J, Moldoveanu Z, Michalek SM, Morrow CD, Compans RW, Schafer DP, Russell MW. Current options for vaccine delivery systems by mucosal routes Journal of Controlled Release. 48: 243-257. DOI: 10.1016/S0168-3659(97)00036-9  0.096
2022 Eitan C, Siany A, Barkan E, Olender T, van Eijk KR, Moisse M, Farhan SMK, Danino YM, Yanowski E, Marmor-Kollet H, Rivkin N, Yacovzada NS, Hung ST, Cooper-Knock J, Yu CH, ... ... Schafer DP, et al. Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS. Nature Neuroscience. PMID 35361972 DOI: 10.1038/s41593-022-01040-6  0.092
2022 Wang IH, Murray E, Andrews G, Jiang HC, Park SJ, Donnard E, Durán-Laforet V, Bear DM, Faust TE, Garber M, Baer CE, Schafer DP, Weng Z, Chen F, Macosko EZ, et al. Spatial transcriptomic reconstruction of the mouse olfactory glomerular map suggests principles of odor processing. Nature Neuroscience. 25: 484-492. PMID 35314823 DOI: 10.1038/s41593-022-01030-8  0.092
1996 Schafer DP. Towards a new world system: A cultural perspective Futures. 28: 285-299.  0.047
1993 Novak M, Moldoveanu Z, Schafer DP, Mestecky J, Compans RW. Murine model for evaluation of protective immunity to influenza virus. Vaccine. 11: 55-60. PMID 8427037 DOI: 10.1016/0264-410X(93)90339-Y  0.043
1994 Schafer DP. Cultures and economies. Irresistible forces encounter immovable objects Futures. 26: 830-845. DOI: 10.1016/0016-3287(94)90059-0  0.036
1996 Duncan JD, Wang PX, Harrington CM, Schafer DP, Matsuoka Y, Mestecky JF, Compans RW, Novak MJ. Comparative analysis of oral delivery systems for live rotavirus vaccines Journal of Controlled Release. 41: 237-247. DOI: 10.1016/0168-3659(96)01331-4  0.034
2002 Schafer DP. In-licensing as a business model. Nature Biotechnology. 20: BE36-9. PMID 12089585 DOI: 10.1038/nbt0602supp-BE36  0.01
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