Year |
Citation |
Score |
2023 |
Falco JA, Wynia-Smith SL, McCoy J, Smith BC, Weerapana E. Identification of Protein Targets of -Nitroso-Coenzyme A-Mediated -Nitrosation Using Chemoproteomics. Acs Chemical Biology. PMID 38159293 DOI: 10.1021/acschembio.3c00654 |
0.327 |
|
2022 |
Canarelli SE, Swalm BM, Larson ET, Morrison MJ, Weerapana E. Monitoring GAPDH activity and inhibition with cysteine-reactive chemical probes. Rsc Chemical Biology. 3: 972-982. PMID 35866162 DOI: 10.1039/d2cb00091a |
0.359 |
|
2021 |
Bak DW, Weerapana E. Chemoproteomic interrogation of selenocysteine by low-pH isoTOP-ABPP. Methods in Enzymology. 662: 187-225. PMID 35101210 DOI: 10.1016/bs.mie.2021.10.003 |
0.303 |
|
2021 |
Isor A, Chartier BV, Abo M, Currens ER, Weerapana E, McCulla RD. Identifying cysteine residues susceptible to oxidation by photoactivatable atomic oxygen precursors using a proteome-wide analysis. Rsc Chemical Biology. 2: 577-591. PMID 34458801 DOI: 10.1039/d0cb00200c |
0.501 |
|
2020 |
Annand JR, Henderson AR, Cole KS, Maurais AJ, Becerra J, Liu Y, Weerapana E, Koehler AN, Mapp AK, Schindler CS. Gibberellin JRA-003: A Selective Inhibitor of Nuclear Translocation of IKKα. Acs Medicinal Chemistry Letters. 11: 1913-1918. PMID 33062173 DOI: 10.1021/Acsmedchemlett.9B00613 |
0.615 |
|
2020 |
Perez M, Bak DW, Bergholtz SE, Crooks DR, Arimilli BS, Yang Y, Weerapana E, Linehan WM, Meier JL. Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite. The Journal of Biological Chemistry. PMID 32820045 DOI: 10.1074/Jbc.Ac120.014993 |
0.395 |
|
2020 |
Peeler JC, Falco JA, Kelemen RE, Abo M, Chartier BV, Edinger LC, Chen J, Chatterjee A, Weerapana E. Generation of Recombinant Mammalian Selenoproteins through Genetic Code Expansion with Photocaged Selenocysteine. Acs Chemical Biology. PMID 32330002 DOI: 10.1021/Acschembio.0C00147 |
0.555 |
|
2020 |
Keller LJ, Lentz CS, Chen YE, Metivier RJ, Weerapana E, Fischbach M, Bogyo M. Characterization of serine hydrolases across clinical isolates of commensal skin bacteria Staphylococcus epidermidis using activity-based protein profiling. Acs Infectious Diseases. PMID 32298574 DOI: 10.1021/Acsinfecdis.0C00095 |
0.333 |
|
2020 |
Italia JS, Peeler JC, Hillenbrand CM, Latour C, Weerapana E, Chatterjee A. Genetically encoded protein sulfation in mammalian cells. Nature Chemical Biology. 16: 379-382. PMID 32198493 DOI: 10.1038/S41589-020-0493-1 |
0.36 |
|
2020 |
Yoo E, Schulze CJ, Stokes BH, Onguka O, Yeo T, Mok S, Gnädig NF, Zhou Y, Kurita K, Foe IT, Terrell SM, Boucher MJ, Cieplak P, Kumpornsin K, Lee MCS, ... ... Weerapana E, et al. The Antimalarial Natural Product Salinipostin A Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites. Cell Chemical Biology. PMID 31978322 DOI: 10.1016/J.Chembiol.2020.01.001 |
0.647 |
|
2020 |
Bechtel TJ, Li C, Kisty EA, Maurais AJ, Weerapana E. Profiling cysteine reactivity and oxidation in the endoplasmic reticulum. Acs Chemical Biology. PMID 31899610 DOI: 10.1021/Acschembio.9B01014 |
0.378 |
|
2019 |
Morimoto K, Cole KS, Kourelis J, Witt CH, Brown D, Krahn D, Stegmann M, Kaschani F, Kaiser M, Burton J, Mohammed S, Yamaguchi-Shinozaki K, Weerapana E, van der Hoorn RAL. Triazine Probes Target Ascorbate Peroxidases in Plants. Plant Physiology. 180: 1848-1859. PMID 33885892 DOI: 10.1104/pp.19.00481 |
0.587 |
|
2019 |
Peeler JC, Weerapana E. Chemical Biology Approaches to Interrogate the Selenoproteome. Accounts of Chemical Research. PMID 31523956 DOI: 10.1021/Acs.Accounts.9B00379 |
0.399 |
|
2019 |
Engelberg K, Chen CT, Bechtel T, Sánchez Guzmán V, Drozda AA, Chavan S, Weerapana E, Gubbels MJ. The apical annuli of Toxoplasma gondii are composed of coiled-coil and signaling proteins embedded in the IMC sutures. Cellular Microbiology. e13112. PMID 31470470 DOI: 10.1111/Cmi.13112 |
0.368 |
|
2019 |
Hoffman KS, Vargas-Rodriguez O, Bak DW, Mukai T, Woodward LK, Weerapana E, Söll D, Reynolds NM. A cysteinyl-tRNA synthetase variant confers resistance against selenite toxicity and decreases selenocysteine misincorporation. The Journal of Biological Chemistry. PMID 31296657 DOI: 10.1074/Jbc.Ra119.008219 |
0.351 |
|
2019 |
Mondal S, Gong X, Zhang X, Salinger AJ, Zheng L, Sen S, Weerapana E, Zhang X, Thompson P. Halogen Bonding Increases the Potency and Isozyme-selectivity of Protein Arginine Deiminase 1 Inhibitors. Angewandte Chemie (International Ed. in English). PMID 31276611 DOI: 10.1002/Anie.201906334 |
0.42 |
|
2019 |
Zheng L, Nagar M, Maurais AJ, Slade DJ, Parelkar SS, Coonrod SA, Weerapana E, Thompson PR. Calcium Regulates the Nuclear Localization of Protein Arginine Deiminase 2. Biochemistry. PMID 31243954 DOI: 10.1021/Acs.Biochem.9B00225 |
0.328 |
|
2019 |
Morimoto K, Cole KS, Kourelis J, Witt CH, Brown D, Krahn D, Stegmann M, Kaschani F, Kaiser M, Burton J, Mohammed S, Yamaguchi-Shinozaki K, Weerapana E, van der Hoorn RAL. Triazine probes targeting ascorbate peroxidases in plants. Plant Physiology. PMID 31138623 DOI: 10.1104/Pp.19.00481 |
0.621 |
|
2019 |
Llabani E, Hicklin RW, Lee HY, Motika SE, Crawford LA, Weerapana E, Hergenrother PJ. Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis. Nature Chemistry. PMID 31086302 DOI: 10.1038/S41557-019-0261-6 |
0.347 |
|
2019 |
Bak DW, Weerapana E. Interrogation of Functional Mitochondrial Cysteine Residues by Quantitative Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 1967: 211-227. PMID 31069773 DOI: 10.1007/978-1-4939-9187-7_13 |
0.34 |
|
2019 |
Sen S, Mondal S, Zheng L, Salinger AJ, Fast W, Weerapana E, Thompson PR. Development of a Suicide Inhibition Based Protein Labeling (SIBLing) Strategy for Nicotinamide N-methyltransferase. Acs Chemical Biology. PMID 30933557 DOI: 10.1021/Acschembio.9B00211 |
0.407 |
|
2019 |
Italia JS, Addy PS, Erickson SB, Peeler JC, Weerapana E, Chatterjee A. Mutually orthogonal nonsense-suppression systems and conjugation chemistries for precise protein labeling at up to three distinct sites. Journal of the American Chemical Society. PMID 30909694 DOI: 10.1021/Jacs.8B12954 |
0.397 |
|
2019 |
Maurais AJ, Weerapana E. Reactive-cysteine profiling for drug discovery. Current Opinion in Chemical Biology. 50: 29-36. PMID 30897495 DOI: 10.1016/J.Cbpa.2019.02.010 |
0.443 |
|
2019 |
Kulkarni RA, Bak DW, Wei D, Bergholtz SE, Briney CA, Shrimp JH, Alpsoy A, Thorpe AL, Bavari AE, Crooks DR, Levy M, Florens L, Washburn MP, Frizzell N, Dykhuizen EC, ... Weerapana E, et al. A chemoproteomic portrait of the oncometabolite fumarate. Nature Chemical Biology. PMID 30718813 DOI: 10.1038/S41589-018-0217-Y |
0.343 |
|
2019 |
Bergholtz SE, Briney CA, Kulkarni RA, Wei D, Bak DW, Shrimp JH, Weerapana E, Linehan WM, Meier JL. Abstract 2759: Chemoproteomic profiling of the oncometabolite fumarate Cancer Research. 79: 2759-2759. DOI: 10.1158/1538-7445.Am2019-2759 |
0.35 |
|
2018 |
Long MJC, Lawson AP, Baggio R, Qian Y, Rozhansky L, Fasci D, El Oualid F, Weerapana E, Hedstrom L. Diarylcarbonates are a new class of deubiquitinating enzyme inhibitor. Bioorganic & Medicinal Chemistry Letters. PMID 30528168 DOI: 10.1016/J.Bmcl.2018.11.055 |
0.417 |
|
2018 |
Bak DW, Bechtel TJ, Falco JA, Weerapana E. Cysteine reactivity across the subcellular universe. Current Opinion in Chemical Biology. 48: 96-105. PMID 30508703 DOI: 10.1016/J.Cbpa.2018.11.002 |
0.413 |
|
2018 |
Gao J, Yang F, Che J, Han Y, Wang Y, Chen N, Bak DW, Lai S, Xie X, Weerapana E, Wang C. Selenium-Encoded Isotopic Signature Targeted Profiling. Acs Central Science. 4: 960-970. PMID 30159393 DOI: 10.1021/Acscentsci.8B00112 |
0.524 |
|
2018 |
Luo W, Guo F, McMahon A, Couvertier S, Jin H, Diaz M, Fieldsend A, Weerapana E, Rosbash M. NonA and CPX Link the Circadian Clockwork to Locomotor Activity in Drosophila. Neuron. PMID 30057203 DOI: 10.1016/J.Neuron.2018.07.001 |
0.303 |
|
2018 |
Nemmara VV, Tilvawala R, Salinger AJ, Miller L, Nguyen SH, Weerapana E, Thompson PR. Citrullination Inactivates Nicotinamide-N-methyltransferase. Acs Chemical Biology. PMID 30044909 DOI: 10.1021/Acschembio.8B00578 |
0.314 |
|
2018 |
Bak DW, Gao J, Wang C, Weerapana E. A Quantitative Chemoproteomic Platform to Monitor Selenocysteine Reactivity within a Complex Proteome. Cell Chemical Biology. PMID 29983274 DOI: 10.1016/J.Chembiol.2018.05.017 |
0.505 |
|
2018 |
Lentz CS, Sheldon JR, Crawford LA, Cooper R, Garland M, Amieva MR, Weerapana E, Skaar EP, Bogyo M. Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP). Nature Chemical Biology. PMID 29769740 DOI: 10.1038/S41589-018-0060-1 |
0.383 |
|
2018 |
Tilvawala R, Nguyen SH, Maurais AJ, Nemmara VV, Nagar M, Salinger AJ, Nagpal S, Weerapana E, Thompson PR. The Rheumatoid Arthritis-Associated Citrullinome. Cell Chemical Biology. PMID 29628436 DOI: 10.1016/J.Chembiol.2018.03.002 |
0.341 |
|
2018 |
Cole KS, Grandjean JMD, Chen K, Witt CH, O'Day J, Shoulders MD, Wiseman RL, Weerapana E. Characterization of an A-Site Selective Protein Disulfide Isomerase A1 Inhibitor. Biochemistry. PMID 29521097 DOI: 10.1021/Acs.Biochem.8B00178 |
0.674 |
|
2018 |
Nemmara VJ, Subramanian V, Muth A, Mondal S, Salinger AJ, Maurais AJ, Tilvawala R, Weerapana E, Thompson PR. The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs). Acs Chemical Biology. PMID 29341591 DOI: 10.1021/Acschembio.7B00957 |
0.399 |
|
2017 |
Abo M, Li C, Weerapana E. Isotopically-Labeled Iodoacetamide-Alkyne Probes for Quantitative Cysteine-Reactivity Profiling. Molecular Pharmaceutics. PMID 29172527 DOI: 10.1021/Acs.Molpharmaceut.7B00832 |
0.584 |
|
2017 |
Abo M, Li C, Weerapana E. Isotopically-Labeled Iodoacetamide-Alkyne Probes for Quantitative Cysteine-Reactivity Profiling. Molecular Pharmaceutics. PMID 29172527 DOI: 10.1021/Acs.Molpharmaceut.7B00832 |
0.584 |
|
2017 |
Gorelenkova Miller O, Cole KS, Emerson CC, Allimuthu D, Golczak M, Stewart PL, Weerapana E, Adams DJ, Mieyal JJ. Novel chloroacetamido compound CWR-J02 is an anti-inflammatory glutaredoxin-1 inhibitor. Plos One. 12: e0187991. PMID 29155853 DOI: 10.1371/Journal.Pone.0187991 |
0.632 |
|
2017 |
Abo M, Weerapana E. Chemical Probes for Redox Signaling and Oxidative Stress. Antioxidants & Redox Signaling. PMID 29132214 DOI: 10.1089/Ars.2017.7408 |
0.572 |
|
2017 |
Lawson AP, Bak DW, Shannon DA, Long MJC, Vijaykumar T, Yu R, Oualid FE, Weerapana E, Hedstrom L. Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry. Oncotarget. 8: 51296-51316. PMID 28881649 DOI: 10.18632/Oncotarget.17261 |
0.357 |
|
2017 |
Quinti L, Dayalan Naidu S, Träger U, Chen X, Kegel-Gleason K, Llères D, Connolly C, Chopra V, Low C, Moniot S, Sapp E, Tousley AR, Vodicka P, Van Kanegan MJ, Kaltenbach LS, ... ... Weerapana E, et al. KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533375 DOI: 10.1073/Pnas.1614943114 |
0.339 |
|
2017 |
Casas-Selves M, Zhang A, Dowling JE, Hallen S, Kawatkar A, Pace NJ, Denz C, Pontz T, Garahdaghi F, Cao Q, Sabirsh A, Thakur K, O'Connell N, Hu J, Cornella-Taracido I, ... Weerapana E, et al. Target deconvolution efforts on Wnt pathway screen reveal dual modulation of oxidative phosphorylation and SERCA2. Chemmedchem. PMID 28371485 DOI: 10.1002/Cmdc.201700028 |
0.378 |
|
2017 |
Child MA, Garland M, Foe I, Madzelan P, Treeck M, van der Linden WA, Oresic Bender K, Weerapana E, Wilson MA, Boothroyd JC, Reese ML, Bogyo M. Toxoplasma DJ-1 Regulates Organelle Secretion by a Direct Interaction with Calcium-Dependent Protein Kinase 1. Mbio. 8. PMID 28246362 DOI: 10.1128/Mbio.02189-16 |
0.355 |
|
2017 |
Bak DW, Pizzagalli MD, Weerapana E. Identifying Functional Cysteine Residues in the Mitochondria. Acs Chemical Biology. PMID 28157297 DOI: 10.1021/Acschembio.6B01074 |
0.346 |
|
2017 |
Weerapana E. Redox regulation: Taking AKTion on HNEs. Nature Chemical Biology. PMID 28114275 DOI: 10.1038/Nchembio.2311 |
0.301 |
|
2017 |
Bechtel TJ, Weerapana E. From structure to redox: the diverse functional roles of disulfides and implications in disease. Proteomics. PMID 28044432 DOI: 10.1002/Pmic.201600391 |
0.388 |
|
2017 |
Qian Y, Weerapana E. A Quantitative Mass-Spectrometry Platform to Monitor Changes in Cysteine Reactivity. Methods in Molecular Biology (Clifton, N.J.). 1491: 11-22. PMID 27778278 DOI: 10.1007/978-1-4939-6439-0_2 |
0.43 |
|
2017 |
Casás-Selves M, Zhang AX, Dowling JE, Hallén S, Kawatkar A, Pace NJ, Denz CR, Pontz T, Garahdaghi F, Cao Q, Sabirsh A, Thakur K, O'Connell N, Hu J, Cornella-Taracido I, ... Weerapana E, et al. Cover Picture: Target Deconvolution Efforts on Wnt Pathway Screen Reveal Dual Modulation of Oxidative Phosphorylation and SERCA2 (ChemMedChem 12/2017) Chemmedchem. 12: 860-860. DOI: 10.1002/Cmdc.201700341 |
0.302 |
|
2016 |
Abo M, Bak DW, Weerapana E. Optimization of Caged Electrophiles for Improved Monitoring of Cysteine Reactivity in Living Cells. Chembiochem : a European Journal of Chemical Biology. PMID 27813293 DOI: 10.1002/Cbic.201600524 |
0.632 |
|
2016 |
Martell J, Seo Y, Bak DW, Kingsley SF, Tissenbaum HA, Weerapana E. Global Cysteine-Reactivity Profiling during Impaired Insulin/IGF-1 Signaling in C. elegans Identifies Uncharacterized Mediators of Longevity. Cell Chemical Biology. PMID 27499530 DOI: 10.1016/J.Chembiol.2016.06.015 |
0.367 |
|
2016 |
Zhou Y, Wynia-Smith SL, Couvertier SM, Kalous KS, Marletta MA, Smith BC, Weerapana E. Chemoproteomic Strategy to Quantitatively Monitor Transnitrosation Uncovers Functionally Relevant S-Nitrosation Sites on Cathepsin D and HADH2. Cell Chemical Biology. PMID 27291402 DOI: 10.1016/J.Chembiol.2016.05.008 |
0.439 |
|
2016 |
Samarasinghe KT, Munkanatta Godage DN, Zhou Y, Ndombera FT, Weerapana E, Ahn YH. A clickable glutathione approach for identification of protein glutathionylation in response to glucose metabolism. Molecular Biosystems. PMID 27216279 DOI: 10.1039/C6Mb00175K |
0.313 |
|
2016 |
Louie SM, Grossman EA, Crawford LA, Ding L, Camarda R, Huffman TR, Miyamoto DK, Goga A, Weerapana E, Nomura DK. GSTP1 Is a Driver of Triple-Negative Breast Cancer Cell Metabolism and Pathogenicity. Cell Chemical Biology. PMID 27185638 DOI: 10.1016/J.Chembiol.2016.03.017 |
0.549 |
|
2016 |
Crawford LA, Weerapana E. A tyrosine-reactive irreversible inhibitor for glutathione S-transferase Pi (GSTP1). Molecular Biosystems. PMID 27113843 DOI: 10.1039/C6Mb00250A |
0.387 |
|
2016 |
Hatzios SK, Abel S, Martell J, Hubbard T, Sasabe J, Munera D, Clark L, Bachovchin DA, Qadri F, Ryan ET, Davis BM, Weerapana E, Waldor MK. Chemoproteomic profiling of host and pathogen enzymes active in cholera. Nature Chemical Biology. PMID 26900865 DOI: 10.1038/Nchembio.2025 |
0.331 |
|
2015 |
Lawson AP, Long MJ, Coffey RT, Qian Y, Weerapana E, El Oualid F, Hedstrom L. Naturally occurring isothiocyanates exert anticancer effects by inhibiting deubiquitinating enzymes. Cancer Research. PMID 26542215 DOI: 10.1158/0008-5472.Can-15-1544 |
0.392 |
|
2015 |
Clancy KW, Weerapana E, Thompson PR. Detection and identification of protein citrullination in complex biological systems. Current Opinion in Chemical Biology. 30: 1-6. PMID 26517730 DOI: 10.1016/J.Cbpa.2015.10.014 |
0.409 |
|
2015 |
Lewallen DM, Bicker KL, Subramanian V, Clancy KW, Slade DJ, Martell J, Dreyton CJ, Sokolove J, Weerapana E, Thompson PR. Chemical Proteomic Platform To Identify Citrullinated Proteins. Acs Chemical Biology. PMID 26360112 DOI: 10.1021/Acschembio.5B00438 |
0.351 |
|
2015 |
Abo M, Weerapana E. A Caged Electrophilic Probe for Global Analysis of Cysteine Reactivity in Living Cells. Journal of the American Chemical Society. 137: 7087-90. PMID 26020833 DOI: 10.1021/Jacs.5B04350 |
0.603 |
|
2015 |
Bertozzi CR, Stockwell BR, Kubicek S, Dickinson BC, Chang CJ, Schultz C, Silver PA, Gestwicki JE, Chiosis G, Chattopadhyay A, Butcher RA, Park SB, Shoichet BK, Flitsch SL, Zhang J, ... ... Weerapana E, et al. Voices of chemical biology Nature Chemical Biology. 11: 378-379. PMID 25978987 DOI: 10.1038/Nchembio.1820 |
0.462 |
|
2015 |
Bak DW, Weerapana E. Cysteine-mediated redox signalling in the mitochondria. Molecular Biosystems. 11: 678-97. PMID 25519845 DOI: 10.1039/C4Mb00571F |
0.338 |
|
2015 |
Shannon DA, Weerapana E. Covalent protein modification: the current landscape of residue-specific electrophiles. Current Opinion in Chemical Biology. 24: 18-26. PMID 25461720 DOI: 10.1016/J.Cbpa.2014.10.021 |
0.454 |
|
2015 |
Wei Y, Stec B, Redfield AG, Weerapana E, Roberts MF. Phospholipid-binding sites of phosphatase and tensin homolog (PTEN): exploring the mechanism of phosphatidylinositol 4,5-bisphosphate activation. The Journal of Biological Chemistry. 290: 1592-606. PMID 25429968 DOI: 10.1074/Jbc.M114.588590 |
0.349 |
|
2014 |
Couvertier SM, Zhou Y, Weerapana E. Chemical-proteomic strategies to investigate cysteine posttranslational modifications. Biochimica Et Biophysica Acta. 1844: 2315-2330. PMID 25291386 DOI: 10.1016/J.Bbapap.2014.09.024 |
0.493 |
|
2014 |
Shannon DA, Banerjee R, Webster ER, Bak DW, Wang C, Weerapana E. Investigating the proteome reactivity and selectivity of aryl halides. Journal of the American Chemical Society. 136: 3330-3. PMID 24548313 DOI: 10.1021/Ja4116204 |
0.679 |
|
2014 |
Zhuang J, Kuo CH, Chou LY, Liu DY, Weerapana E, Tsung CK. Optimized metal-organic-framework nanospheres for drug delivery: evaluation of small-molecule encapsulation. Acs Nano. 8: 2812-9. PMID 24506773 DOI: 10.1021/Nn406590Q |
0.478 |
|
2014 |
Martell J, Weerapana E. Applications of copper-catalyzed click chemistry in activity-based protein profiling. Molecules (Basel, Switzerland). 19: 1378-93. PMID 24473203 DOI: 10.3390/Molecules19021378 |
0.444 |
|
2014 |
Wang C, Weerapana E, Blewett MM, Cravatt BF. A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles. Nature Methods. 11: 79-85. PMID 24292485 DOI: 10.1038/Nmeth.2759 |
0.655 |
|
2014 |
Pace NJ, Weerapana E. A competitive chemical-proteomic platform to identify zinc-binding cysteines. Acs Chemical Biology. 9: 258-65. PMID 24111988 DOI: 10.1021/Cb400622Q |
0.357 |
|
2014 |
Shannon DA, Weerapana E. Orphan PTMs: Rare, yet functionally important modifications of cysteine. Biopolymers. 101: 156-64. PMID 23564220 DOI: 10.1002/Bip.22252 |
0.412 |
|
2014 |
Tamburini F, Kelly T, Weerapana E, Byers JA. Paper to Plastics: An Interdisciplinary Summer Outreach Project in Sustainability Journal of Chemical Education. 91: 1574-1579. DOI: 10.1021/Ed400892T |
0.49 |
|
2013 |
Schwaid AG, Shannon DA, Ma J, Slavoff SA, Levin JZ, Weerapana E, Saghatelian A. Chemoproteomic discovery of cysteine-containing human short open reading frames. Journal of the American Chemical Society. 135: 16750-3. PMID 24152191 DOI: 10.1021/Ja406606J |
0.587 |
|
2013 |
Child MA, Hall CI, Beck JR, Ofori LO, Albrow VE, Garland M, Bowyer PW, Bradley PJ, Powers JC, Boothroyd JC, Weerapana E, Bogyo M. Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion. Nature Chemical Biology. 9: 651-6. PMID 23934245 DOI: 10.1038/Nchembio.1315 |
0.343 |
|
2013 |
Lee BC, Péterfi Z, Hoffmann FW, Moore RE, Kaya A, Avanesov A, Tarrago L, Zhou Y, Weerapana E, Fomenko DE, Hoffmann PR, Gladyshev VN. MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation. Molecular Cell. 51: 397-404. PMID 23911929 DOI: 10.1016/J.Molcel.2013.06.019 |
0.355 |
|
2013 |
Qian Y, Martell J, Pace NJ, Ballard TE, Johnson DS, Weerapana E. An isotopically tagged azobenzene-based cleavable linker for quantitative proteomics. Chembiochem : a European Journal of Chemical Biology. 14: 1410-4. PMID 23861326 DOI: 10.1002/Cbic.201300396 |
0.335 |
|
2013 |
Gu C, Shannon DA, Colby T, Wang Z, Shabab M, Kumari S, Villamor JG, McLaughlin CJ, Weerapana E, Kaiser M, Cravatt BF, van der Hoorn RA. Chemical proteomics with sulfonyl fluoride probes reveals selective labeling of functional tyrosines in glutathione transferases. Chemistry & Biology. 20: 541-8. PMID 23601643 DOI: 10.1016/J.Chembiol.2013.01.016 |
0.58 |
|
2013 |
Deng X, Weerapana E, Ulanovskaya O, Sun F, Liang H, Ji Q, Ye Y, Fu Y, Zhou L, Li J, Zhang H, Wang C, Alvarez S, Hicks LM, Lan L, et al. Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria. Cell Host & Microbe. 13: 358-70. PMID 23498960 DOI: 10.1016/J.Chom.2013.02.004 |
0.606 |
|
2013 |
Banerjee R, Pace NJ, Brown DR, Weerapana E. 1,3,5-Triazine as a modular scaffold for covalent inhibitors with streamlined target identification. Journal of the American Chemical Society. 135: 2497-500. PMID 23379904 DOI: 10.1021/Ja400427E |
0.619 |
|
2013 |
Pace NJ, Weerapana E. Diverse functional roles of reactive cysteines. Acs Chemical Biology. 8: 283-96. PMID 23163700 DOI: 10.1021/Cb3005269 |
0.435 |
|
2013 |
Ramya TN, Weerapana E, Cravatt BF, Paulson JC. Glycoproteomics enabled by tagging sialic acid- or galactose-terminated glycans. Glycobiology. 23: 211-21. PMID 23070960 DOI: 10.1093/Glycob/Cws144 |
0.536 |
|
2013 |
Banerjee R, Brown DR, Weerapana E. Recent developments in the synthesis of bioactive 2,4,6-trisubstituted 1,3,5-triazines Synlett. 24: 1599-1605. DOI: 10.1055/S-0033-1339284 |
0.563 |
|
2012 |
Shannon DA, Gu C, McLaughlin CJ, Kaiser M, van der Hoorn RA, Weerapana E. Sulfonyl fluoride analogues as activity-based probes for serine proteases. Chembiochem : a European Journal of Chemical Biology. 13: 2327-30. PMID 23008217 DOI: 10.1002/Cbic.201200531 |
0.383 |
|
2012 |
Pace NJ, Pimental DR, Weerapana E. An inhibitor of glutathione S-transferase omega 1 that selectively targets apoptotic cells. Angewandte Chemie (International Ed. in English). 51: 8365-8. PMID 22777685 DOI: 10.1002/Anie.201203730 |
0.342 |
|
2012 |
Tarrago L, Kaya A, Weerapana E, Marino SM, Gladyshev VN. Methionine sulfoxide reductases preferentially reduce unfolded oxidized proteins and protect cells from oxidative protein unfolding. The Journal of Biological Chemistry. 287: 24448-59. PMID 22628550 DOI: 10.1074/Jbc.M112.374520 |
0.42 |
|
2012 |
Shannon DA, Gu C, McLaughlin CJ, Kaiser M, van der Hoorn RAL, Weerapana E. Cover Picture: Sulfonyl Fluoride Analogues as Activity-Based Probes for Serine Proteases (ChemBioChem 16/2012) Chembiochem. 13: 2309-2309. DOI: 10.1002/Cbic.201290066 |
0.331 |
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2011 |
Hall CI, Reese ML, Weerapana E, Child MA, Bowyer PW, Albrow VE, Haraldsen JD, Phillips MR, Sandoval ED, Ward GE, Cravatt BF, Boothroyd JC, Bogyo M. Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion. Proceedings of the National Academy of Sciences of the United States of America. 108: 10568-73. PMID 21670272 DOI: 10.1073/Pnas.1105622108 |
0.497 |
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2011 |
Bachovchin DA, Zuhl AM, Speers AE, Wolfe MR, Weerapana E, Brown SJ, Rosen H, Cravatt BF. Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. Journal of Medicinal Chemistry. 54: 5229-36. PMID 21639134 DOI: 10.1021/Jm200502U |
0.772 |
|
2011 |
Ahn K, Smith SE, Liimatta MB, Beidler D, Sadagopan N, Dudley DT, Young T, Wren P, Zhang Y, Swaney S, Van Becelaere K, Blankman JL, Nomura DK, Bhattachar SN, Stiff C, ... ... Weerapana E, et al. Mechanistic and pharmacological characterization of PF-04457845: a highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and noninflammatory pain. The Journal of Pharmacology and Experimental Therapeutics. 338: 114-24. PMID 21505060 DOI: 10.1124/Jpet.111.180257 |
0.653 |
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2010 |
Weerapana E, Wang C, Simon GM, Richter F, Khare S, Dillon MB, Bachovchin DA, Mowen K, Baker D, Cravatt BF. Quantitative reactivity profiling predicts functional cysteines in proteomes. Nature. 468: 790-5. PMID 21085121 DOI: 10.1038/Nature09472 |
0.745 |
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2010 |
Wurdak H, Zhu S, Min KH, Aimone L, Lairson LL, Watson J, Chopiuk G, Demas J, Charette B, Halder R, Weerapana E, Cravatt BF, Cline HT, Peters EC, Zhang J, et al. A small molecule accelerates neuronal differentiation in the adult rat. Proceedings of the National Academy of Sciences of the United States of America. 107: 16542-7. PMID 20823227 DOI: 10.1073/Pnas.1010300107 |
0.453 |
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2010 |
Johnson DS, Weerapana E, Cravatt BF. Strategies for discovering and derisking covalent, irreversible enzyme inhibitors. Future Medicinal Chemistry. 2: 949-64. PMID 20640225 DOI: 10.4155/Fmc.10.21 |
0.568 |
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2010 |
Ramya TN, Weerapana E, Liao L, Zeng Y, Tateno H, Liao L, Yates JR, Cravatt BF, Paulson JC. In situ trans ligands of CD22 identified by glycan-protein photocross-linking-enabled proteomics. Molecular & Cellular Proteomics : McP. 9: 1339-51. PMID 20172905 DOI: 10.1074/Mcp.M900461-Mcp200 |
0.435 |
|
2009 |
Ahn K, Johnson DS, Mileni M, Beidler D, Long JZ, McKinney MK, Weerapana E, Sadagopan N, Liimatta M, Smith SE, Lazerwith S, Stiff C, Kamtekar S, Bhattacharya K, Zhang Y, et al. Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. Chemistry & Biology. 16: 411-20. PMID 19389627 DOI: 10.1016/J.Chembiol.2009.02.013 |
0.757 |
|
2008 |
Weerapana E, Simon GM, Cravatt BF. Disparate proteome reactivity profiles of carbon electrophiles. Nature Chemical Biology. 4: 405-7. PMID 18488014 DOI: 10.1038/Nchembio.91 |
0.695 |
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2007 |
Chen MM, Weerapana E, Ciepichal E, Stupak J, Reid CW, Swiezewska E, Imperiali B. Polyisoprenol specificity in the Campylobacter jejuni N-linked glycosylation pathway. Biochemistry. 46: 14342-8. PMID 18034500 DOI: 10.1021/Bi701956X |
0.574 |
|
2007 |
Weerapana E, Speers AE, Cravatt BF. Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)--a general method for mapping sites of probe modification in proteomes. Nature Protocols. 2: 1414-25. PMID 17545978 DOI: 10.1038/Nprot.2007.194 |
0.773 |
|
2007 |
Hanson SR, Hsu TL, Weerapana E, Kishikawa K, Simon GM, Cravatt BF, Wong CH. Tailored glycoproteomics and glycan site mapping using saccharide-selective bioorthogonal probes. Journal of the American Chemical Society. 129: 7266-7. PMID 17506567 DOI: 10.1021/Ja0724083 |
0.697 |
|
2006 |
Glover KJ, Weerapana E, Chen MM, Imperiali B. Direct biochemical evidence for the utilization of UDP-bacillosamine by PglC, an essential glycosyl-1-phosphate transferase in the Campylobacter jejuni N-linked glycosylation pathway. Biochemistry. 45: 5343-50. PMID 16618123 DOI: 10.1021/Bi0602056 |
0.537 |
|
2006 |
Weerapana E, Imperiali B. Asparagine-linked protein glycosylation: from eukaryotic to prokaryotic systems. Glycobiology. 16: 91R-101R. PMID 16510493 DOI: 10.1093/Glycob/Cwj099 |
0.558 |
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2005 |
Glover KJ, Weerapana E, Numao S, Imperiali B. Chemoenzymatic synthesis of glycopeptides with PglB, a bacterial oligosaccharyl transferase from Campylobacter jejuni. Chemistry & Biology. 12: 1311-5. PMID 16356848 DOI: 10.1016/J.Chembiol.2005.10.004 |
0.577 |
|
2005 |
Weerapana E, Glover KJ, Chen MM, Imperiali B. Investigating bacterial N-linked glycosylation: synthesis and glycosyl acceptor activity of the undecaprenyl pyrophosphate-linked bacillosamine. Journal of the American Chemical Society. 127: 13766-7. PMID 16201778 DOI: 10.1021/Ja054265V |
0.583 |
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2005 |
Glover KJ, Weerapana E, Imperiali B. In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation. Proceedings of the National Academy of Sciences of the United States of America. 102: 14255-9. PMID 16186480 DOI: 10.1073/Pnas.0507311102 |
0.549 |
|
2003 |
Weerapana E, Imperiali B. Peptides to peptidomimetics: towards the design and synthesis of bioavailable inhibitors of oligosaccharyl transferase. Organic & Biomolecular Chemistry. 1: 93-9. PMID 12929394 DOI: 10.1039/B209342A |
0.576 |
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