| Year |
Citation |
Score |
| 2023 |
York JM, Borghese CM, George AA, Cannatella DC, Zakon HH. A potential cost of evolving epibatidine resistance in poison frogs. Biorxiv : the Preprint Server For Biology. PMID 36711899 DOI: 10.1101/2023.01.04.522789 |
0.314 |
|
| 2022 |
Arias HR, Borghese CM, Germann AL, Pierce SR, Bonardi A, Nocentini A, Gratteri P, Thodati TM, Lim NJ, Harris RA, Akk G. (+)-Catharanthine potentiates the GABA receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loop. Biochemical Pharmacology. 199: 114993. PMID 35304861 DOI: 10.1016/j.bcp.2022.114993 |
0.404 |
|
| 2021 |
Borghese CM, Wang HL, McHardy SF, Messing RO, Trudell JR, Harris RA, Bertaccini EJ. Modulation of α1β3γ2 GABA receptors expressed in oocytes using a propofol photoswitch tethered to the transmembrane helix. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33593898 DOI: 10.1073/pnas.2008178118 |
0.531 |
|
| 2020 |
Blednov YA, Borghese CM, Dugan MP, Pradhan S, Thodati TM, Kichili NR, Harris RA, Messing RO. Apremilast regulates acute effects of ethanol and other GABAergic drugs via protein kinase A-dependent signaling. Neuropharmacology. 108220. PMID 32736086 DOI: 10.1016/J.Neuropharm.2020.108220 |
0.512 |
|
| 2017 |
Tarvin RD, Borghese CM, Sachs W, Santos JC, Lu Y, O'Connell LA, Cannatella DC, Harris RA, Zakon HH. Interacting amino acid replacements allow poison frogs to evolve epibatidine resistance. Science (New York, N.Y.). 357: 1261-1266. PMID 28935799 DOI: 10.1126/Science.Aan5061 |
0.448 |
|
| 2017 |
Borghese CM, Herman M, Snell LD, Lawrence KJ, Lee HY, Backos DS, Vanderlinden LA, Harris RA, Roberto M, Hoffman PL, Tabakoff B. Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes. Scientific Reports. 7: 6230. PMID 28740086 DOI: 10.1038/S41598-017-05966-X |
0.654 |
|
| 2017 |
Blednov YA, Borghese CM, Ruiz CI, Cullins MA, Da Costa A, Osterndorff-Kahanek EA, Homanics GE, Harris RA. Mutation of the inhibitory ethanol site in GABAA ρ1 receptors promotes tolerance to ethanol-induced motor incoordination. Neuropharmacology. PMID 28623169 DOI: 10.1016/J.Neuropharm.2017.06.013 |
0.543 |
|
| 2015 |
Borghese CM, Ruiz CI, Lee US, Cullins MA, Bertaccini EJ, Trudell JR, Harris RA. Identification of an Inhibitory Alcohol Binding Site in GABAA ρ1 Receptors. Acs Chemical Neuroscience. PMID 26571107 DOI: 10.1021/Acschemneuro.5B00246 |
0.553 |
|
| 2014 |
Blednov YA, Benavidez JM, Black M, Leiter CR, Osterndorff-Kahanek E, Johnson D, Borghese CM, Hanrahan JR, Johnston GA, Chebib M, Harris RA. GABAA receptors containing ρ1 subunits contribute to in vivo effects of ethanol in mice. Plos One. 9: e85525. PMID 24454882 DOI: 10.1371/Journal.Pone.0085525 |
0.535 |
|
| 2014 |
Borghese CM, Hicks JA, Lapid DJ, Trudell JR, Harris RA. GABA(A) receptor transmembrane amino acids are critical for alcohol action: disulfide cross-linking and alkyl methanethiosulfonate labeling reveal relative location of binding sites. Journal of Neurochemistry. 128: 363-75. PMID 24117469 DOI: 10.1111/Jnc.12476 |
0.54 |
|
| 2013 |
Heusser SA, Howard RJ, Borghese CM, Cullins MA, Broemstrup T, Lee US, Lindahl E, Carlsson J, Harris RA. Functional validation of virtual screening for novel agents with general anesthetic action at ligand-gated ion channels. Molecular Pharmacology. 84: 670-8. PMID 23950219 DOI: 10.1124/Mol.113.087692 |
0.572 |
|
| 2012 |
Borghese CM, Harris RA. Alcohol Dependence and Genes Encoding α2 and γ1 GABAA Receptor Subunits: Insights from Humans and Mice. Alcohol Research : Current Reviews. 34: 345-53. PMID 23134051 |
0.513 |
|
| 2012 |
Borghese CM, Xiong W, Oh SI, Ho A, Mihic SJ, Zhang L, Lovinger DM, Homanics GE, Eger EI, Harris RA. Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice. Anesthesiology. 117: 765-71. PMID 22885675 DOI: 10.1097/Aln.0B013E31826A0D93 |
0.686 |
|
| 2012 |
Borghese CM, Blednov YA, Quan Y, Iyer SV, Xiong W, Mihic SJ, Zhang L, Lovinger DM, Trudell JR, Homanics GE, Harris RA. Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols. The Journal of Pharmacology and Experimental Therapeutics. 340: 304-16. PMID 22037201 DOI: 10.1124/Jpet.111.185116 |
0.7 |
|
| 2010 |
McCracken ML, Borghese CM, Trudell JR, Harris RA. A transmembrane amino acid in the GABAA receptor β2 subunit critical for the actions of alcohols and anesthetics. The Journal of Pharmacology and Experimental Therapeutics. 335: 600-6. PMID 20826568 DOI: 10.1124/Jpet.110.170472 |
0.602 |
|
| 2008 |
Reilly MT, Lobo IA, McCracken LM, Borghese CM, Gong D, Horishita T, Harris RA. Effects of acamprosate on neuronal receptors and ion channels expressed in Xenopus oocytes. Alcoholism, Clinical and Experimental Research. 32: 188-96. PMID 18226119 DOI: 10.1111/J.1530-0277.2007.00569.X |
0.618 |
|
| 2007 |
Borghese CM, Harris RA. Studies of ethanol actions on recombinant delta-containing gamma-aminobutyric acid type A receptors yield contradictory results. Alcohol (Fayetteville, N.Y.). 41: 155-62. PMID 17521845 DOI: 10.1016/J.Alcohol.2007.03.006 |
0.584 |
|
| 2006 |
Werner DF, Blednov YA, Ariwodola OJ, Silberman Y, Logan E, Berry RB, Borghese CM, Matthews DB, Weiner JL, Harrison NL, Harris RA, Homanics GE. Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol. The Journal of Pharmacology and Experimental Therapeutics. 319: 219-27. PMID 16785315 DOI: 10.1124/Jpet.106.106161 |
0.56 |
|
| 2006 |
Borghese CM, Stórustovu SÃ, Ebert B, Herd MB, Belelli D, Lambert JJ, Marshall G, Wafford KA, Harris RA. The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol. The Journal of Pharmacology and Experimental Therapeutics. 316: 1360-8. PMID 16272217 DOI: 10.1124/Jpet.105.092452 |
0.484 |
|
| 2005 |
Liao M, Sonner JM, Jurd R, Rudolph U, Borghese CM, Harris RA, Laster MJ, Eger EI. Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane. Anesthesia and Analgesia. 101: 412-8, table of cont. PMID 16037154 DOI: 10.1213/01.Ane.0000154196.86587.35 |
0.569 |
|
| 2003 |
Borghese CM, Henderson LA, Bleck V, Trudell JR, Harris RA. Sites of excitatory and inhibitory actions of alcohols on neuronal alpha2beta4 nicotinic acetylcholine receptors. The Journal of Pharmacology and Experimental Therapeutics. 307: 42-52. PMID 14500778 DOI: 10.1124/Jpet.102.053710 |
0.486 |
|
| 2003 |
Borghese CM, Wang L, Bleck V, Harris RA. Mutation in neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes blocks ethanol action. Addiction Biology. 8: 313-8. PMID 13129833 DOI: 10.1080/13556210310001602220 |
0.497 |
|
| 2003 |
Lopreato GF, Phelan R, Borghese CM, Beckstead MJ, Mihic SJ. Inhaled drugs of abuse enhance serotonin-3 receptor function. Drug and Alcohol Dependence. 70: 11-5. PMID 12681521 DOI: 10.1016/S0376-8716(02)00330-7 |
0.684 |
|
| 2003 |
Borghese CM, Ali DN, Bleck V, Harris RA. Acetylcholine and alcohol sensitivity of neuronal nicotinic acetylcholine receptors: mutations in transmembrane domains. Alcoholism, Clinical and Experimental Research. 26: 1764-72. PMID 12500099 DOI: 10.1097/01.ALC.0000042012.58231.D9 |
0.535 |
|
| 2002 |
Borghese CM, Harris RA. Anesthetic-induced immobility: Neuronal nicotinic acetylcholine receptors are no longer in the picture Anesthesia and Analgesia. 95: 509-511. PMID 12198026 |
0.449 |
|
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