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Aaron A. Goodarzi, Ph.D. - Publications

Affiliations: 
Biochemistry and Molecular Biology University of Calgary, Calgary, Alberta, Canada 
Area:
DNA Repair, Chromatin Remodelling
Website:
http://ucalgary.ca/bmb/profiles/dr-aaron-goodarzi
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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Danforth JM, Provencher L, Goodarzi AA. Chromatin and the Cellular Response to Particle Radiation-Induced Oxidative and Clustered DNA Damage. Frontiers in Cell and Developmental Biology. 10: 910440. PMID 35912116 DOI: 10.3389/fcell.2022.910440  0.526
2022 Berger ND, Brownlee PM, Chen MJ, Morrison H, Osz K, Ploquin NP, Chan JA, Goodarzi AA. High replication stress and limited Rad51-mediated DNA repair capacity, but not oxidative stress, underlie oligodendrocyte precursor cell radiosensitivity. Nar Cancer. 4: zcac012. PMID 35425901 DOI: 10.1093/narcan/zcac012  0.442
2020 Stanley FKT, Berger ND, Pearson DD, Danforth JM, Morrison H, Johnston JE, Warnock TS, Brenner DR, Chan JA, Pierce G, Cobb JA, Ploquin NP, Goodarzi AA. A high-throughput alpha particle irradiation system for monitoring DNA damage repair, genome instability and screening in human cell and yeast model systems. Nucleic Acids Research. PMID 33010172 DOI: 10.1093/nar/gkaa782  0.376
2019 Stanley FKT, Irvine JL, Jacques WR, Salgia SR, Innes DG, Winquist BD, Torr D, Brenner DR, Goodarzi AA. Radon exposure is rising steadily within the modern North American residential environment, and is increasingly uniform across seasons. Scientific Reports. 9: 18472. PMID 31796862 DOI: 10.1038/S41598-019-54891-8  0.322
2019 Moore S, Berger ND, Luijsterburg MS, Piett CG, Stanley FKT, Schräder CU, Fang S, Chan JA, Schriemer DC, Nagel ZD, van Attikum H, Goodarzi AA. The CHD6 chromatin remodeler is an oxidative DNA damage response factor. Nature Communications. 10: 241. PMID 30651562 DOI: 10.1038/S41467-018-08111-Y  0.553
2017 Berger ND, Stanley FKT, Moore S, Goodarzi AA. ATM-dependent pathways of chromatin remodelling and oxidative DNA damage responses. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28847820 DOI: 10.1098/Rstb.2016.0283  0.616
2017 Klement K, Goodarzi AA. Analyzing Heterochromatic DNA Double Strand Break (DSB) Repair in Response to Ionizing Radiation. Methods in Molecular Biology (Clifton, N.J.). 1599: 303-315. PMID 28477128 DOI: 10.1007/978-1-4939-6955-5_22  0.618
2017 Stanley FK, Zarezadeh S, Dumais CD, Dumais K, MacQueen R, Clement F, Goodarzi AA. Comprehensive survey of household radon gas levels and risk factors in southern Alberta. Cmaj Open. 5: E255-E264. PMID 28401142 DOI: 10.9778/cmajo.20160142  0.737
2016 Hansen RK, Mund A, Poulsen SL, Sandoval M, Klement K, Tsouroula K, Tollenaere MA, Räschle M, Soria R, Offermanns S, Worzfeld T, Grosse R, Brandt DT, Rozell B, Mann M, ... ... Goodarzi AA, et al. SCAI promotes DNA double-strand break repair in distinct chromosomal contexts. Nature Cell Biology. PMID 27820601 DOI: 10.1038/Ncb3436  0.59
2014 Klement K, Luijsterburg MS, Pinder JB, Cena CS, Del Nero V, Wintersinger CM, Dellaire G, van Attikum H, Goodarzi AA. Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repair. The Journal of Cell Biology. 207: 717-33. PMID 25533843 DOI: 10.1083/Jcb.201405077  0.582
2014 Klement K, Goodarzi AA. DNA double strand break responses and chromatin alterations within the aging cell. Experimental Cell Research. 329: 42-52. PMID 25218945 DOI: 10.1016/J.Yexcr.2014.09.003  0.55
2014 Moore S, Stanley FK, Goodarzi AA. The repair of environmentally relevant DNA double strand breaks caused by high linear energy transfer irradiation--no simple task. Dna Repair. 17: 64-73. PMID 24565812 DOI: 10.1016/J.Dnarep.2014.01.014  0.806
2013 Kakarougkas A, Ismail A, Klement K, Goodarzi AA, Conrad S, Freire R, Shibata A, Lobrich M, Jeggo PA. Opposing roles for 53BP1 during homologous recombination. Nucleic Acids Research. 41: 9719-31. PMID 23969417 DOI: 10.1093/Nar/Gkt729  0.662
2013 Stanley FK, Moore S, Goodarzi AA. CHD chromatin remodelling enzymes and the DNA damage response. Mutation Research. 750: 31-44. PMID 23954449 DOI: 10.1016/J.Mrfmmm.2013.07.008  0.789
2013 Goodarzi AA, Jeggo PA. The repair and signaling responses to DNA double-strand breaks. Advances in Genetics. 82: 1-45. PMID 23721719 DOI: 10.1016/B978-0-12-407676-1.00001-9  0.72
2012 Goodarzi AA, Jeggo PA. The heterochromatic barrier to DNA double strand break repair: how to get the entry visa. International Journal of Molecular Sciences. 13: 11844-60. PMID 23109886 DOI: 10.3390/Ijms130911844  0.733
2012 Lee DH, Goodarzi AA, Adelmant GO, Pan Y, Jeggo PA, Marto JA, Chowdhury D. Phosphoproteomic analysis reveals that PP4 dephosphorylates KAP-1 impacting the DNA damage response. The Embo Journal. 31: 2403-15. PMID 22491012 DOI: 10.1038/Emboj.2012.86  0.693
2012 Goodarzi AA, Jeggo PA. Irradiation induced foci (IRIF) as a biomarker for radiosensitivity. Mutation Research. 736: 39-47. PMID 21651917 DOI: 10.1016/J.Mrfmmm.2011.05.017  0.632
2011 Noon AT, Goodarzi AA. 53BP1-mediated DNA double strand break repair: insert bad pun here. Dna Repair. 10: 1071-6. PMID 21868291 DOI: 10.1016/J.Dnarep.2011.07.012  0.632
2011 Brunton H, Goodarzi AA, Noon AT, Shrikhande A, Hansen RS, Jeggo PA, Shibata A. Analysis of human syndromes with disordered chromatin reveals the impact of heterochromatin on the efficacy of ATM-dependent G2/M checkpoint arrest. Molecular and Cellular Biology. 31: 4022-35. PMID 21791604 DOI: 10.1128/Mcb.05289-11  0.67
2011 Goodarzi AA, Kurka T, Jeggo PA. KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response. Nature Structural & Molecular Biology. 18: 831-9. PMID 21642969 DOI: 10.1038/Nsmb.2077  0.718
2011 Woodbine L, Brunton H, Goodarzi AA, Shibata A, Jeggo PA. Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair. Nucleic Acids Research. 39: 6986-97. PMID 21596788 DOI: 10.1093/Nar/Gkr331  0.74
2011 Lobrich M, Goodarzi AA, Stiff T, Jeggo PA. Checkpoint control following radiation exposure Current Cancer Research. 19: 53-77. DOI: 10.1007/978-1-4419-8044-1_3  0.488
2010 Goodarzi AA, Jeggo P, Lobrich M. The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax. Dna Repair. 9: 1273-82. PMID 21036673 DOI: 10.1016/J.Dnarep.2010.09.013  0.739
2010 Woodbine L, Grigoriadou S, Goodarzi AA, Riballo E, Tape C, Oliver AW, van Zelm MC, Buckland MS, Davies EG, Pearl LH, Jeggo PA. An Artemis polymorphic variant reduces Artemis activity and confers cellular radiosensitivity. Dna Repair. 9: 1003-10. PMID 20674517 DOI: 10.1016/J.Dnarep.2010.07.001  0.57
2010 Shibata A, Barton O, Noon AT, Dahm K, Deckbar D, Goodarzi AA, Löbrich M, Jeggo PA. Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest. Molecular and Cellular Biology. 30: 3371-83. PMID 20421415 DOI: 10.1128/Mcb.01644-09  0.703
2010 Löbrich M, Shibata A, Beucher A, Fisher A, Ensminger M, Goodarzi AA, Barton O, Jeggo PA. gammaH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization. Cell Cycle (Georgetown, Tex.). 9: 662-9. PMID 20139725 DOI: 10.4161/Cc.9.4.10764  0.715
2010 Noon AT, Shibata A, Rief N, Löbrich M, Stewart GS, Jeggo PA, Goodarzi AA. 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. Nature Cell Biology. 12: 177-84. PMID 20081839 DOI: 10.1038/Ncb2017  0.71
2010 Lee JH, Goodarzi AA, Jeggo PA, Paull TT. 53BP1 promotes ATM activity through direct interactions with the MRN complex. The Embo Journal. 29: 574-85. PMID 20010693 DOI: 10.1038/Emboj.2009.372  0.673
2009 Goodarzi AA, Jeggo PA. 'A mover and a shaker': 53BP1 allows DNA doublestrand breaks a chance to dance and unite. F1000 Biology Reports. 1: 21. PMID 20948664 DOI: 10.3410/B1-21  0.719
2009 Beucher A, Birraux J, Tchouandong L, Barton O, Shibata A, Conrad S, Goodarzi AA, Krempler A, Jeggo PA, Löbrich M. ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2. The Embo Journal. 28: 3413-27. PMID 19779458 DOI: 10.1038/Emboj.2009.276  0.704
2009 Goodarzi AA, Noon AT, Jeggo PA. The impact of heterochromatin on DSB repair. Biochemical Society Transactions. 37: 569-76. PMID 19442252 DOI: 10.1042/Bst0370569  0.719
2009 Riballo E, Woodbine L, Stiff T, Walker SA, Goodarzi AA, Jeggo PA. XLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligation. Nucleic Acids Research. 37: 482-92. PMID 19056826 DOI: 10.1093/Nar/Gkn957  0.681
2008 Goodarzi AA, Noon AT, Deckbar D, Ziv Y, Shiloh Y, Löbrich M, Jeggo PA. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Molecular Cell. 31: 167-77. PMID 18657500 DOI: 10.1016/J.Molcel.2008.05.017  0.693
2008 Shibata A, Barton O, Noon AT, Dahm K, Deckbar D, Goodarzi AA, Löbrich M, Jeggo PA. The maintenance of ATM dependent G2/M checkpoint arrest following exposure to ionizing radiation Acta Medica Nagasakiensia. 53: 19-21.  0.526
2008 Goodarzi AA, Noon AT, Jeggo PA. Heterochromatic DNA double strand break repair Acta Medica Nagasakiensia. 53: 13-17.  0.683
2007 Goodarzi AA, Douglas P, Moorhead GB, Lees-Miller SP. Utilizing protein phosphatase inhibitors to define PP2A as a regulator of ataxia-telangiectasia mutated. Methods in Molecular Biology (Clifton, N.J.). 365: 47-59. PMID 17200553 DOI: 10.1385/1-59745-267-X:47  0.646
2006 Stiff T, Walker SA, Cerosaletti K, Goodarzi AA, Petermann E, Concannon P, O'Driscoll M, Jeggo PA. ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling. The Embo Journal. 25: 5775-82. PMID 17124492 DOI: 10.1038/Sj.Emboj.7601446  0.7
2006 Goodarzi AA, Yu Y, Riballo E, Douglas P, Walker SA, Ye R, Härer C, Marchetti C, Morrice N, Jeggo PA, Lees-Miller SP. DNA-PK autophosphorylation facilitates Artemis endonuclease activity. The Embo Journal. 25: 3880-9. PMID 16874298 DOI: 10.1038/Sj.Emboj.7601255  0.79
2004 Goodarzi AA, Jonnalagadda JC, Douglas P, Young D, Ye R, Moorhead GB, Lees-Miller SP, Khanna KK. Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A. The Embo Journal. 23: 4451-61. PMID 15510216 DOI: 10.1038/Sj.Emboj.7600455  0.641
2004 Goodarzi AA, Lees-Miller SP. Biochemical characterization of the ataxia-telangiectasia mutated (ATM) protein from human cells. Dna Repair. 3: 753-67. PMID 15177184 DOI: 10.1016/J.Dnarep.2004.03.041  0.702
2004 Ye R, Goodarzi AA, Kurz EU, Saito S, Higashimoto Y, Lavin MF, Appella E, Anderson CW, Lees-Miller SP. The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX. Dna Repair. 3: 235-44. PMID 15177039 DOI: 10.1016/J.Dnarep.2003.10.014  0.742
2003 Goodarzi AA, Block WD, Lees-Miller SP. The role of ATM and ATR in DNA damage-induced cell cycle control. Progress in Cell Cycle Research. 5: 393-411. PMID 14593734  0.714
2002 Sapkota GP, Deak M, Kieloch A, Morrice N, Goodarzi AA, Smythe C, Shiloh Y, Lees-Miller SP, Alessi DR. Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366. The Biochemical Journal. 368: 507-16. PMID 12234250 DOI: 10.1042/Bj20021284  0.69
2002 Douglas P, Sapkota GP, Morrice N, Yu Y, Goodarzi AA, Merkle D, Meek K, Alessi DR, Lees-Miller SP. Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase. The Biochemical Journal. 368: 243-51. PMID 12186630 DOI: 10.1042/Bj20020973  0.746
2002 Saito S, Goodarzi AA, Higashimoto Y, Noda Y, Lees-Miller SP, Appella E, Anderson CW. ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation. The Journal of Biological Chemistry. 277: 12491-4. PMID 11875057 DOI: 10.1074/Jbc.C200093200  0.688
2001 Curman D, Cinel B, Williams DE, Rundle N, Block WD, Goodarzi AA, Hutchins JR, Clarke PR, Zhou BB, Lees-Miller SP, Andersen RJ, Roberge M. Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine. The Journal of Biological Chemistry. 276: 17914-9. PMID 11279124 DOI: 10.1074/Jbc.M100728200  0.705
2000 Chan DW, Son SC, Block W, Ye R, Khanna KK, Wold MS, Douglas P, Goodarzi AA, Pelley J, Taya Y, Lavin MF, Lees-Miller SP. Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase. The Journal of Biological Chemistry. 275: 7803-10. PMID 10713094 DOI: 10.1074/Jbc.275.11.7803  0.654
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