Nicholas A. Castello, Ph.D. - Related publications

Affiliations: 
Neurobiology & Behavior University of California, Irvine, Irvine, CA 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Kim TW, Park SS, Park JY, Park HS. Infusion of Plasma from Exercised Mice Ameliorates Cognitive Dysfunction by Increasing Hippocampal Neuroplasticity and Mitochondrial Functions in 3xTg-AD Mice. International Journal of Molecular Sciences. 21. PMID 32384696 DOI: 10.3390/ijms21093291   
2020 Pérez-González M, Mendioroz M, Badesso S, Sucunza D, Roldan M, Espelosín M, Ursua S, Luján R, Cuadrado-Tejedor M, Garcia-Osta A. PLA2G4E, a candidate gene for resilience in Alzheimer´s disease and a new target for dementia treatment. Progress in Neurobiology. 101818. PMID 32380223 DOI: 10.1016/j.pneurobio.2020.101818   
2020 Ferreiro E, Lanzillo M, Canhoto D, Carvalho da Silva AM, Mota SI, Dias IS, Ferreira IL, Fontes AR, Mastrella G, Pinheiro P, Valero J, Rego AC. Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer's disease mouse model. Neurobiology of Aging. 92: 98-113. PMID 32417750 DOI: 10.1016/j.neurobiolaging.2020.04.003   
2020 Vyas Y, Montgomery JM, Cheyne JE. Hippocampal Deficits in Amyloid-β-Related Rodent Models of Alzheimer's Disease. Frontiers in Neuroscience. 14: 266. PMID 32317913 DOI: 10.3389/fnins.2020.00266   
2020 Kim KY, Suh YH, Chang KA. Therapeutic Effects of Human Amniotic Epithelial Stem Cells in a Transgenic Mouse Model of Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32290355 DOI: 10.3390/ijms21072658   
2020 Tan YX, Liu GC, Chen HL, Lu MN, Chen B, Hu T, Zhang L, Mao R, Li S, Mei R, Wang XY, Xiyang YB. Exercise-Induced Cognitive Improvement Is Associated with Sodium Channel-Mediated Excitability in APP/PS1 Mice. Neural Plasticity. 2020: 9132720. PMID 32256560 DOI: 10.1155/2020/9132720   
2020 Liu B, Kou J, Li F, Huo D, Xu J, Zhou X, Meng D, Ghulam M, Artyom B, Gao X, Ma N, Han D. Lemon essential oil ameliorates age-associated cognitive dysfunction via modulating hippocampal synaptic density and inhibiting acetylcholinesterase. Aging. 12. PMID 32392535 DOI: 10.18632/aging.103179   
2020 Lu MH, Zhao XY, Xu DE, Chen JB, Ji WL, Huang ZP, Pan TT, Xue LL, Wang F, Li QF, Zhang Y, Wang TH, Yanagawa Y, Liu CF, Xu RX, et al. Transplantation of GABAergic Interneuron Progenitor Attenuates Cognitive Deficits of Alzheimer's Disease Model Mice. Journal of Alzheimer's Disease : Jad. PMID 32280096 DOI: 10.3233/JAD-200010   
2020 Gee MS, Son SH, Jeon SH, Do J, Kim N, Ju YJ, Lee SJ, Chung EK, Inn KS, Kim NJ, Lee JK. A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse. Alzheimer's Research & Therapy. 12: 45. PMID 32317025 DOI: 10.1186/s13195-020-00617-2   
2020 Ghosh S, Durgvanshi S, Agarwal S, Raghunath M, Sinha JK. Current status of drug targets and emerging therapeutic strategies in the management of Alzheimer's disease. Current Neuropharmacology. PMID 32348223 DOI: 10.2174/1570159X18666200429011823   
2020 Abd-Elrahman KS, Hamilton A, Albaker A, Ferguson SSG. mGluR5 Contribution to Neuropathology in Alzheimer Mice Is Disease Stage-Dependent. Acs Pharmacology & Translational Science. 3: 334-344. PMID 32296772 DOI: 10.1021/acsptsci.0c00013   
2020 Li N, Wang G, Lu H. Development of Alzheimer's Disease after Myocardial Infarction. Journal of Alzheimer's Disease : Jad. PMID 32280100 DOI: 10.3233/JAD-200068   
2020 Sultan S, Taimuri U, Basnan SA, Ai-Orabi WK, Awadallah A, Almowald F, Hazazi A. Low Vitamin D and Its Association with Cognitive Impairment and Dementia. Journal of Aging Research. 2020: 6097820. PMID 32399297 DOI: 10.1155/2020/6097820   
2020 Zameer S, Alam M, Hussain S, Vohora D, Ali J, Akhtar M. Neuroprotective role of alendronate against APP processing and neuroinflammation in mice fed a high fat diet. Brain Research Bulletin. PMID 32389800 DOI: 10.1016/j.brainresbull.2020.04.010   
2020 Wilson GD, Wilson TG, Hanna A, Kulchycki J, Buelow K, Pruetz BL, Michael DB, Chinnaiyan P, Maddens ME, Martinez AA, Fontanesi J. Low Dose Brain Irradiation Reduces Amyloid-β and Tau in 3xTg-AD Mice. Journal of Alzheimer's Disease : Jad. PMID 32280098 DOI: 10.3233/JAD-200030   
2020 Andrade V, Cortés N, Pastor G, Gonzalez A, Ramos-Escobar N, Pastene E, Rojo LE, Maccioni RB. N-Acetyl Cysteine and Catechin-Derived Polyphenols: A Path Toward Multi-Target Compounds Against Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32390631 DOI: 10.3233/JAD-200067   
2020 Kou X, Chen D, Chen N. The Regulation of microRNAs in Alzheimer's Disease. Frontiers in Neurology. 11: 288. PMID 32362867 DOI: 10.3389/fneur.2020.00288   
2020 Yang Y, Zhou J, Li J. Regulation of exosome for Alzheimer's disease derived from mesenchymal stem cells. Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences. 45: 169-175. PMID 32386043 DOI: 10.11817/j.issn.1672-7347.2020.180779   
2020 Hongo N, Takamura Y, Nishimaru H, Matsumoto J, Tobe K, Saito T, Saido TC, Nishijo H. Astaxanthin Ameliorated Parvalbumin-Positive Neuron Deficits and Alzheimer's Disease-Related Pathological Progression in the Hippocampus of Mice. Frontiers in Pharmacology. 11: 307. PMID 32218736 DOI: 10.3389/fphar.2020.00307   
2020 Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. The presubiculum links incipient amyloid and tau pathology to memory function in older persons. Neurology. PMID 32273431 DOI: 10.1212/WNL.0000000000009362   
2020 Yang ZX, Tang CL, Li XH, Zhu ZW, Qiu L, An HY, Wu MJ, Yang YH. [Effect of electroacupuncture combined with Donepezil on learning-memory ability and expression of hippocampal β-amyloid clearance-related genes in SAMP8 mice]. Zhen Ci Yan Jiu = Acupuncture Research. 45: 281-6. PMID 32333532 DOI: 10.13702/j.1000-0607.190081   
2020 Song YY, Xu WT, Zhang XC, Ni GX. Mechanisms of Electroacupuncture on Alzheimer's Disease: A Review of Animal Studies. Chinese Journal of Integrative Medicine. PMID 32318906 DOI: 10.1007/s11655-020-3092-9   
2020 Meng Q, Lin MS, Tzeng IS. Relationship Between Exercise and Alzheimer's Disease: A Narrative Literature Review. Frontiers in Neuroscience. 14: 131. PMID 32273835 DOI: 10.3389/fnins.2020.00131   
2020 Xu Y, Hu R, He D, Zhou G, Wu H, Xu C, He B, Wu L, Wang Y, Chang Y, Ma R, Xie M, Xiao Z. Bisdemethoxycurcumin inhibits oxidative stress and antagonizes Alzheimer's disease by up-regulating SIRT1. Brain and Behavior. e01655. PMID 32441492 DOI: 10.1002/brb3.1655   
2020 Li Z, Chen Q, Liu J, Du Y. Physical Exercise Ameliorates the Cognitive Function and Attenuates the Neuroinflammation of Alzheimer's Disease via miR-129-5p. Dementia and Geriatric Cognitive Disorders. 1-7. PMID 32434194 DOI: 10.1159/000507285   
2020 Xu XD, Teng Y, Zou JY, Ye Y, Song H, Wang ZY. Effects of lycopene on vascular remodeling through the LXR-PI3K-AKT signaling pathway in APP/PS1 mice. Biochemical and Biophysical Research Communications. PMID 32253029 DOI: 10.1016/j.bbrc.2020.02.063   
2020 Pichet Binette A, Vachon-Presseau É, Morris J, Bateman R, Benzinger T, Collins DL, Poirier J, Breitner JCS, Villeneuve S, , . Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease. Biological Psychiatry. PMID 32228870 DOI: 10.1016/j.biopsych.2020.01.023   
2020 Zetterberg H, Bendlin BB. Biomarkers for Alzheimer's disease-preparing for a new era of disease-modifying therapies. Molecular Psychiatry. PMID 32251378 DOI: 10.1038/s41380-020-0721-9   
2020 Lim KH, Joo JY. Predictive Potential of Circulating Ube2h mRNA as an E2 Ubiquitin-Conjugating Enzyme for Diagnosis or Treatment of Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32403399 DOI: 10.3390/ijms21093398   
2020 Haque RU, Pongos AL, Manzaneres CM, Lah JJ, Levey AI, Clifford GD. Deep convolutional neural networks and transfer learning for measuring cognitive impairment using eye-tracking in a distributed tablet-based environment. Ieee Transactions On Bio-Medical Engineering. PMID 32340935 DOI: 10.1109/TBME.2020.2990734   
2020 Liu B, Huang B, Liu J, Shi JS. Dendrobium nobile Lindl alkaloid and metformin ameliorate cognitive dysfunction in senescence-accelerated mice via suppression of endoplasmic reticulum stress. Brain Research. 146871. PMID 32380088 DOI: 10.1016/j.brainres.2020.146871   
2020 Wang F, Wang F, Chen T. Secondary metabolites of from ameliorate cognitive deficits and brain oxidative stress in D-galactose induced Alzheimer's disease mouse model. Natural Product Research. 1-6. PMID 32292060 DOI: 10.1080/14786419.2020.1753738   
2020 Barthet G, Mulle C. Presynaptic failure in Alzheimer's disease. Progress in Neurobiology. 101801. PMID 32428558 DOI: 10.1016/j.pneurobio.2020.101801   
2020 Wu L, Zheng Q, Guo YY, Zhang KN, Luo J, Xiao S, Li WJ, Yang M. Effect of Zhenxin Xingshui Yizhi Fang on Aβ induced expression of related transporters in HBMEC cell model. Journal of Ethnopharmacology. 112783. PMID 32240783 DOI: 10.1016/j.jep.2020.112783   
2020 Kong Y, Peng Q, Lv N, Yuan J, Deng Z, Liang X, Chen S, Wang L. Paeoniflorin exerts neuroprotective effects in a transgenic mouse model of Alzheimer's disease via activation of adenosine A receptor. Neuroscience Letters. 135016. PMID 32371159 DOI: 10.1016/j.neulet.2020.135016   
2020 Chen Y, Bian Y, Wang JW, Gong TT, Ying YM, Ma LF, Shan WG, Xie XQ, Zhan ZJ. Effects of α-Mangostin Derivatives on the Alzheimer's Disease Model of Rats and Their Mechanism: A Combination of Experimental Study and Computational Systems Pharmacology Analysis. Acs Omega. 5: 9846-9863. PMID 32391472 DOI: 10.1021/acsomega.0c00057   
2020 Zhou F, Yan XD, Wang C, He YX, Li YY, Zhang J, Wang ZJ, Cai HY, Qi JS, Wu MN. Suvorexant ameliorates cognitive impairments and pathology in APP/PS1 transgenic mice. Neurobiology of Aging. PMID 32224066 DOI: 10.1016/j.neurobiolaging.2020.02.020   
2020 Qin T, Prins S, Groeneveld GJ, Van Westen G, de Vries HE, Wong YC, Bischoff LJM, de Lange ECM. Utility of Animal Models to Understand Human Alzheimer's Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals. International Journal of Molecular Sciences. 21. PMID 32365768 DOI: 10.3390/ijms21093158   
2020 Xiao H, Wang Y, Wu Y, Li H, Liang X, Lin Y, Kong L, Ni YN, Deng Y, Li Y, Li W, Yang J. Osthole ameliorates cognitive impairments via augmenting neuronal population in APP / PS1 transgenic mice. Neuroscience Research. PMID 32302734 DOI: 10.1016/j.neures.2020.04.001   
2020 Lin SY, Wang TQ, Xu LT, Lai XX, Shen Y, Lin JW, Gao SY, Hu HY. Qingxin Kaiqiao Recipe Improves Cognitive Performance, Inhibits Apoptosis, and Reduces Pathological Deposits in APP/PS1 Double Transgenic Mice via the PI3K/Akt Pathway. Evidence-Based Complementary and Alternative Medicine : Ecam. 2020: 3019674. PMID 32419798 DOI: 10.1155/2020/3019674   
2020 Liu B, Liu J, Shi JS. SAMP8 Mice as a Model of Age-Related Cognition Decline with Underlying Mechanisms in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32310176 DOI: 10.3233/JAD-200063   
2020 Peng YS, Tang CW, Peng YY, Chang H, Chen CL, Guo SL, Wu LC, Huang MC, Lee HC. Comparative functional genomic analysis of Alzheimer's affected and naturally aging brains. Peerj. 8: e8682. PMID 32219020 DOI: 10.7717/peerj.8682   
2020 Kim DH, Kim HA, Han YS, Jeon WK, Han JS. Recognition memory impairments and amyloid-beta deposition of the retrosplenial cortex at the early stage of 5XFAD mice. Physiology & Behavior. 112891. PMID 32442584 DOI: 10.1016/j.physbeh.2020.112891   
2020 Demarest TG, Varma VR, Estrada D, Babbar M, Basu S, Mahajan UV, Moaddel R, Croteau DL, Thambisetty M, Mattson MP, Bohr VA. Biological sex and DNA repair deficiency drive Alzheimer's disease via systemic metabolic remodeling and brain mitochondrial dysfunction. Acta Neuropathologica. PMID 32333098 DOI: 10.1007/s00401-020-02152-8   
2020 Arora S, Sharma D, Singh J. GLUT-1 an effective target to deliver BDNF gene across blood brain barrier. Acs Chemical Neuroscience. PMID 32352752 DOI: 10.1021/acschemneuro.0c00076   
2020 Novak G, Streffer JR, Timmers M, Henley D, Brashear HR, Bogert J, Russu A, Janssens L, Tesseur I, Tritsmans L, Van Nueten L, Engelborghs S. Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer's disease spectrum patients: a randomized, double-blind, placebo-controlled study and a two-period extension study. Alzheimer's Research & Therapy. 12: 58. PMID 32410694 DOI: 10.1186/s13195-020-00614-5   
2020 Yasar S, Moored KD, Adam A, Zabel F, Chuang YF, Varma VR, Carlson MC. Angiotensin II Blood Levels Are Associated with Smaller Hippocampal and Cortical Volumes in Cognitively Normal Older Adults. Journal of Alzheimer's Disease : Jad. PMID 32280103 DOI: 10.3233/JAD-200118   
2020 Flores-Muñoz C, Gómez B, Mery E, Mujica P, Gajardo I, Córdova C, Lopez-Espíndola D, Durán-Aniotz C, Hetz C, Muñoz P, Gonzalez-Jamett AM, Ardiles ÁO. Acute Pannexin 1 Blockade Mitigates Early Synaptic Plasticity Defects in a Mouse Model of Alzheimer's Disease. Frontiers in Cellular Neuroscience. 14: 46. PMID 32265655 DOI: 10.3389/fncel.2020.00046   
2020 Müller-Thomsen L, Borgmann D, Morcinek K, Schröder S, Dengler B, Moser N, Neumaier F, Schneider T, Schröder H, Huggenberger S. Consequences of hyperphosphorylated tau on the morphology and excitability of hippocampal neurons in aged tau transgenic micew. Neurobiology of Aging. PMID 32278495 DOI: 10.1016/j.neurobiolaging.2020.03.007   
2020 Chen SY, Gao Y, Sun JY, Meng XL, Yang D, Fan LH, Xiang L, Wang P. Traditional Chinese Medicine: Role in Reducing β-Amyloid, Apoptosis, Autophagy, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction of Alzheimer's Disease. Frontiers in Pharmacology. 11: 497. PMID 32390843 DOI: 10.3389/fphar.2020.00497