Morgan Wirthlin, Ph.D. - Publications

Affiliations: 
2005-2009 Biological Sciences University of Chicago, Chicago, IL 
 2010-2016 Behavioral Neuroscience Oregon Health and Science University, Portland, OR 
 2016-2022 Computational Biology Carnegie Mellon University, Pittsburgh, PA 
 2022- Human Cell Types Allen Institute for Brain Science, Seattle, WA, United States 
Area:
vocal learning, evolution of behavior, neurogenomics
Website:
https://www.researchgate.net/profile/Morgan_Wirthlin

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wirthlin ME, Schmid TA, Elie JE, Zhang X, Kowalczyk A, Redlich R, Shvareva VA, Rakuljic A, Ji MB, Bhat NS, Kaplow IM, Schäffer DE, Lawler AJ, Wang AZ, Phan BN, ... ... Wirthlin ME, et al. Vocal learning-associated convergent evolution in mammalian proteins and regulatory elements. Science (New York, N.Y.). eabn3263. PMID 38422184 DOI: 10.1126/science.abn3263  0.363
2023 Kaplow IM, Lawler AJ, Schäffer DE, Srinivasan C, Sestili HH, Wirthlin ME, Phan BN, Prasad K, Brown AR, Zhang X, Foley K, Genereux DP, Karlsson EK, Lindblad-Toh K, Meyer WK, ... ... Wirthlin ME, et al. Relating enhancer genetic variation across mammals to complex phenotypes using machine learning. Science (New York, N.Y.). 380: eabm7993. PMID 37104615 DOI: 10.1126/science.abm7993  0.802
2023 Sullivan PF, Meadows JRS, Gazal S, Phan BN, Li X, Genereux DP, Dong MX, Bianchi M, Andrews G, Sakthikumar S, Nordin J, Roy A, Christmas MJ, Marinescu VD, Wang C, ... ... Wirthlin ME, et al. Leveraging base-pair mammalian constraint to understand genetic variation and human disease. Science (New York, N.Y.). 380: eabn2937. PMID 37104612 DOI: 10.1126/science.abn2937  0.78
2023 Keough KC, Whalen S, Inoue F, Przytycki PF, Fair T, Deng C, Steyert M, Ryu H, Lindblad-Toh K, Karlsson E, Nowakowski T, Ahituv N, Pollen A, Pollard KS, Andrews G, ... ... Wirthlin ME, et al. Three-dimensional genome rewiring in loci with human accelerated regions. Science (New York, N.Y.). 380: eabm1696. PMID 37104607 DOI: 10.1126/science.abm1696  0.366
2023 Kirilenko BM, Munegowda C, Osipova E, Jebb D, Sharma V, Blumer M, Morales AE, Ahmed AW, Kontopoulos DG, Hilgers L, Lindblad-Toh K, Karlsson EK, Hiller M, Andrews G, Armstrong JC, ... ... Wirthlin ME, et al. Integrating gene annotation with orthology inference at scale. Science (New York, N.Y.). 380: eabn3107. PMID 37104600 DOI: 10.1126/science.abn3107  0.318
2023 Christmas MJ, Kaplow IM, Genereux DP, Dong MX, Hughes GM, Li X, Sullivan PF, Hindle AG, Andrews G, Armstrong JC, Bianchi M, Breit AM, Diekhans M, Fanter C, Foley NM, ... ... Wirthlin ME, ... ... Wirthlin ME, et al. Evolutionary constraint and innovation across hundreds of placental mammals. Science (New York, N.Y.). 380: eabn3943. PMID 37104599 DOI: 10.1126/science.abn3943  0.792
2023 Xue JR, Mackay-Smith A, Mouri K, Garcia MF, Dong MX, Akers JF, Noble M, Li X, Lindblad-Toh K, Karlsson EK, Noonan JP, Capellini TD, Brennand KJ, Tewhey R, Sabeti PC, ... ... Wirthlin ME, et al. The functional and evolutionary impacts of human-specific deletions in conserved elements. Science (New York, N.Y.). 380: eabn2253. PMID 37104592 DOI: 10.1126/science.abn2253  0.351
2023 Osmanski AB, Paulat NS, Korstian J, Grimshaw JR, Halsey M, Sullivan KAM, Moreno-Santillán DD, Crookshanks C, Roberts J, Garcia C, Johnson MG, Densmore LD, Stevens RD, Rosen J, Storer JM, ... ... Wirthlin ME, et al. Insights into mammalian TE diversity through the curation of 248 genome assemblies. Science (New York, N.Y.). 380: eabn1430. PMID 37104570 DOI: 10.1126/science.abn1430  0.31
2023 Fuxjager MJ, Ryder TB, Moody NM, Alfonso C, Balakrishnan CN, Barske J, Bosholn M, Boyle WA, Braun EL, Chiver I, Dakin R, Day LB, Driver R, Fusani L, Horton BM, ... ... Wirthlin M, et al. Systems biology as a framework to understand the physiological and endocrine bases of behavior and its evolution-From concepts to a case study in birds. Hormones and Behavior. 151: 105340. PMID 36933440 DOI: 10.1016/j.yhbeh.2023.105340  0.491
2022 Lawler AJ, Ramamurthy E, Brown AR, Shin N, Kim Y, Toong N, Kaplow IM, Wirthlin M, Zhang X, Phan BN, Fox GA, Wade K, He J, Ozturk BE, Byrne LC, et al. Machine learning sequence prioritization for cell type-specific enhancer design. Elife. 11. PMID 35576146 DOI: 10.7554/eLife.69571  0.772
2022 Kaplow IM, Schäffer DE, Wirthlin ME, Lawler AJ, Brown AR, Kleyman M, Pfenning AR. Inferring mammalian tissue-specific regulatory conservation by predicting tissue-specific differences in open chromatin. Bmc Genomics. 23: 291. PMID 35410163 DOI: 10.1186/s12864-022-08450-7  0.716
2021 He J, Kleyman M, Chen J, Alikaya A, Rothenhoefer KM, Ozturk BE, Wirthlin M, Bostan AC, Fish K, Byrne LC, Pfenning AR, Stauffer WR. Transcriptional and anatomical diversity of medium spiny neurons in the primate striatum. Current Biology : Cb. PMID 34727523 DOI: 10.1016/j.cub.2021.10.015  0.728
2021 Srinivasan C, Phan BN, Lawler AJ, Ramamurthy E, Kleyman M, Brown AR, Kaplow IM, Wirthlin ME, Pfenning AR. Addiction-associated genetic variants implicate brain cell type- and region-specific cis-regulatory elements in addiction neurobiology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34462306 DOI: 10.1523/JNEUROSCI.2534-20.2021  0.789
2021 Feng S, Stiller J, Deng Y, Armstrong J, Fang Q, Reeve AH, Xie D, Chen G, Guo C, Faircloth BC, Petersen B, Wang Z, Zhou Q, Diekhans M, Chen W, ... ... Wirthlin M, et al. Author Correction: Dense sampling of bird diversity increases power of comparative genomics. Nature. PMID 33833441 DOI: 10.1038/s41586-021-03473-8  0.646
2020 Feng S, Stiller J, Deng Y, Armstrong J, Fang Q, Reeve AH, Xie D, Chen G, Guo C, Faircloth BC, Petersen B, Wang Z, Zhou Q, Diekhans M, Chen W, ... ... Wirthlin M, et al. Dense sampling of bird diversity increases power of comparative genomics. Nature. 587: 252-257. PMID 33177665 DOI: 10.1038/s41586-020-2873-9  0.701
2020 Nevue AA, Lovell PV, Wirthlin M, Mello CV. Molecular specializations of deep cortical layer analogs in songbirds. Scientific Reports. 10: 18767. PMID 33127988 DOI: 10.1038/s41598-020-75773-4  0.762
2020 Zhang X, Kaplow IM, Wirthlin M, Park TY, Pfenning AR. HALPER facilitates the identification of regulatory element orthologs across species. Bioinformatics (Oxford, England). PMID 32407523 DOI: 10.1093/Bioinformatics/Btaa493  0.75
2020 Lovell PV, Wirthlin M, Kaser T, Buckner AA, Carleton JB, Snider BR, McHugh AK, Tolpygo A, Mitra PP, Mello CV. ZEBrA - Zebra finch Expression Brain Atlas: a resource for comparative molecular neuroanatomy and brain evolution studies. The Journal of Comparative Neurology. PMID 32037563 DOI: 10.1002/Cne.24879  0.713
2019 Wirthlin M, Chang EF, Knörnschild M, Krubitzer LA, Mello CV, Miller CT, Pfenning AR, Vernes SC, Tchernichovski O, Yartsev MM. A Modular Approach to Vocal Learning: Disentangling the Diversity of a Complex Behavioral Trait. Neuron. 104: 87-99. PMID 31600518 DOI: 10.1016/J.Neuron.2019.09.036  0.764
2019 Mello CV, Kaser T, Buckner AA, Wirthlin M, Lovell PV. Molecular architecture of the zebra finch arcopallium. The Journal of Comparative Neurology. PMID 30919954 DOI: 10.1002/Cne.24688  0.712
2018 Wirthlin M, Lima NCB, Guedes RLM, Soares AER, Almeida LGP, Cavaleiro NP, Loss de Morais G, Chaves AV, Howard JT, Teixeira MM, Schneider PN, Santos FR, Schatz MC, Felipe MS, Miyaki CY, et al. Parrot Genomes and the Evolution of Heightened Longevity and Cognition. Current Biology : Cb. PMID 30528582 DOI: 10.1016/J.Cub.2018.10.050  0.746
2018 Lovell PV, Huizinga NA, Getachew A, Mees B, Friedrich SR, Wirthlin M, Mello CV. Curation of microarray oligonucleotides and corresponding ESTs/cDNAs used for gene expression analysis in zebra finches. Bmc Research Notes. 11: 309. PMID 29776372 DOI: 10.1186/S13104-018-3402-X  0.733
2018 Lovell PV, Huizinga NA, Friedrich SR, Wirthlin M, Mello CV. The constitutive differential transcriptome of a brain circuit for vocal learning. Bmc Genomics. 19: 231. PMID 29614959 DOI: 10.1186/S12864-018-4578-0  0.736
2016 Warren WC, Hillier LW, Tomlinson C, Minx P, Kremitzki M, Graves T, Markovic C, Bouk N, Pruitt KD, Thibaud-Nissen F, Schneider V, Mansour TA, Brown CT, Zimin A, Hawken R, ... ... Wirthlin M, et al. A New Chicken Genome Assembly Provides Insight into Avian Genome Structure. G3 (Bethesda, Md.). PMID 27852011 DOI: 10.1534/G3.116.035923  0.718
2015 de Lima JL, Soares FA, Remedios AC, Thom G, Wirthlin M, Aleixo A, Schneider MP, Mello CV, Schneider PN. A putative RA-like region in the brain of the scale-backed antbird, Willisornis poecilinotus (Furnariides, Suboscines, Passeriformes, Thamnophilidae). Genetics and Molecular Biology. 38: 249-54. PMID 26500428 DOI: 10.1590/S1415-475738320150010  0.563
2015 Lovell PV, Wirthlin M, Carbone L, Warren WC, Mello CV. Response to Hron et al. Genome Biology. 16: 165. PMID 26281829 DOI: 10.1186/S13059-015-0725-Y  0.648
2015 Lovell PV, Wirthlin M, Carbone L, Warren WC, Mello CV. Response to Hron et al. Genome Biology. 16. DOI: 10.1186/s13059-015-0725-y  0.586
2014 Lovell PV, Wirthlin M, Wilhelm L, Minx P, Lazar NH, Carbone L, Warren WC, Mello CV. Conserved syntenic clusters of protein coding genes are missing in birds. Genome Biology. 15: 565. PMID 25518852 DOI: 10.1186/S13059-014-0565-1  0.739
2014 Pfenning AR, Hara E, Whitney O, Rivas MV, Wang R, Roulhac PL, Howard JT, Wirthlin M, Lovell PV, Ganapathy G, Mouncastle J, Moseley MA, Thompson JW, Soderblom EJ, Iriki A, et al. Convergent transcriptional specializations in the brains of humans and song-learning birds. Science (New York, N.Y.). 346: 1256846. PMID 25504733 DOI: 10.1126/Science.1256846  0.77
2014 Jarvis ED, Mirarab S, Aberer AJ, Li B, Houde P, Li C, Ho SY, Faircloth BC, Nabholz B, Howard JT, Suh A, Weber CC, da Fonseca RR, Li J, Zhang F, ... ... Wirthlin M, et al. Whole-genome analyses resolve early branches in the tree of life of modern birds. Science (New York, N.Y.). 346: 1320-31. PMID 25504713 DOI: 10.1126/Science.1253451  0.769
2014 Wirthlin M, Lovell PV, Jarvis ED, Mello CV. Comparative genomics reveals molecular features unique to the songbird lineage. Bmc Genomics. 15: 1082. PMID 25494627 DOI: 10.1186/1471-2164-15-1082  0.784
2014 Olson CR, Wirthlin M, Lovell PV, Mello CV. Proper care, husbandry, and breeding guidelines for the zebra finch, Taeniopygia guttata. Cold Spring Harbor Protocols. 2014: 1243-8. PMID 25342067 DOI: 10.1101/Pdb.Prot084780  0.743
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